Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.008 0.103 0.346 2.0 -0.584 8.0 10.0 MAP3K8 0.02 0.013 0.188 2.0 -9999.0 0.0 2.0 FOS 0.004 0.093 0.325 4.0 -0.498 10.0 14.0 PRKCA 0.019 0.008 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.028 0.046 0.187 33.0 -0.423 1.0 34.0 HRAS 0.02 0.009 0.188 1.0 -9999.0 0.0 1.0 PRKCB 0.018 0.031 0.175 3.0 -0.421 2.0 5.0 NRAS 0.019 0.007 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.035 0.015 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.003 0.083 -9999.0 0.0 -0.539 9.0 9.0 MAP2K1 -0.017 0.06 -9999.0 0.0 -0.319 8.0 8.0 ELK1 0.019 0.01 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.004 0.026 -9999.0 0.0 -0.326 3.0 3.0 mol:GTP -0.0 0.001 0.002 1.0 -0.006 12.0 13.0 MAPK1 0.004 0.084 -9999.0 0.0 -0.513 10.0 10.0 RAF1 0.003 0.027 -9999.0 0.0 -0.326 3.0 3.0 KRAS 0.019 0.007 -9999.0 0.0 -9999.0 0.0 0.0