Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.248 0.181 0.365 195.0 -9999.0 0.0 195.0 KIRREL -0.075 0.133 -9999.0 0.0 -0.48 27.0 27.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.248 0.182 -9999.0 0.0 -0.366 195.0 195.0 PLCG1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.01 0.001 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.244 0.182 -9999.0 0.0 -0.333 216.0 216.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.252 0.188 -9999.0 0.0 -0.342 216.0 216.0 FYN -0.234 0.17 -9999.0 0.0 -0.317 216.0 216.0 mol:Ca2+ -0.242 0.18 -9999.0 0.0 -0.33 216.0 216.0 mol:DAG -0.243 0.181 -9999.0 0.0 -0.331 216.0 216.0 NPHS2 -0.196 0.219 -9999.0 0.0 -0.478 109.0 109.0 mol:IP3 -0.243 0.181 -9999.0 0.0 -0.331 216.0 216.0 regulation of endocytosis -0.217 0.164 -9999.0 0.0 -0.297 216.0 216.0 Nephrin/NEPH1/podocin/Cholesterol -0.247 0.18 -9999.0 0.0 -0.334 216.0 216.0 establishment of cell polarity -0.248 0.181 -9999.0 0.0 -0.365 195.0 195.0 Nephrin/NEPH1/podocin/NCK1-2 -0.222 0.171 -9999.0 0.0 -0.304 216.0 216.0 Nephrin/NEPH1/beta Arrestin2 -0.22 0.166 -9999.0 0.0 -0.3 216.0 216.0 NPHS1 -0.305 0.219 -9999.0 0.0 -0.466 187.0 187.0 Nephrin/NEPH1/podocin -0.235 0.172 -9999.0 0.0 -0.318 216.0 216.0 TJP1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.244 0.182 -9999.0 0.0 -0.333 216.0 216.0 CD2AP 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.244 0.182 -9999.0 0.0 -0.333 216.0 216.0 GRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.281 0.187 -9999.0 0.0 -0.348 235.0 235.0 cytoskeleton organization -0.287 0.208 -9999.0 0.0 -0.389 216.0 216.0 Nephrin/NEPH1 -0.173 0.13 -9999.0 0.0 -0.256 195.0 195.0 Nephrin/NEPH1/ZO-1 -0.194 0.149 -9999.0 0.0 -0.289 195.0 195.0