Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.372 0.281 0.552 195.0 -9999.0 0.0 195.0 KIRREL -0.106 0.192 -9999.0 0.0 -0.694 26.0 26.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.373 0.282 -9999.0 0.0 -0.553 195.0 195.0 PLCG1 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.01 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.022 0.012 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.381 0.304 -9999.0 0.0 -0.535 212.0 212.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.317 0.252 -9999.0 0.0 -0.467 188.0 188.0 FYN -0.376 0.266 0.265 1.0 -0.507 212.0 213.0 mol:Ca2+ -0.373 0.297 -9999.0 0.0 -0.533 206.0 206.0 mol:DAG -0.375 0.3 -9999.0 0.0 -0.536 206.0 206.0 NPHS2 -0.289 0.312 -9999.0 0.0 -0.692 107.0 107.0 mol:IP3 -0.375 0.3 -9999.0 0.0 -0.536 206.0 206.0 regulation of endocytosis -0.341 0.269 -9999.0 0.0 -0.483 207.0 207.0 Nephrin/NEPH1/podocin/Cholesterol -0.387 0.297 -9999.0 0.0 -0.537 212.0 212.0 establishment of cell polarity -0.372 0.281 -9999.0 0.0 -0.552 195.0 195.0 Nephrin/NEPH1/podocin/NCK1-2 -0.352 0.29 -9999.0 0.0 -0.503 210.0 210.0 Nephrin/NEPH1/beta Arrestin2 -0.346 0.275 -9999.0 0.0 -0.49 207.0 207.0 NPHS1 -0.446 0.309 -9999.0 0.0 -0.671 187.0 187.0 Nephrin/NEPH1/podocin -0.367 0.284 -9999.0 0.0 -0.51 212.0 212.0 TJP1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.377 0.302 -9999.0 0.0 -0.539 206.0 206.0 CD2AP 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.379 0.302 -9999.0 0.0 -0.54 206.0 206.0 GRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.453 0.295 0.275 1.0 -0.567 229.0 230.0 cytoskeleton organization -0.392 0.303 -9999.0 0.0 -0.583 184.0 184.0 Nephrin/NEPH1 -0.273 0.215 -9999.0 0.0 -0.411 193.0 193.0 Nephrin/NEPH1/ZO-1 -0.302 0.244 -9999.0 0.0 -0.463 191.0 191.0