Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
FLT3	52 (27%)	141	0.00033	0.0035	0.00037	0.00365	9.9999e-06	0.000197	0.00094999	0.00771	0.00197	0.0129	0.00075999	0.00699
DNMT3A	48 (25%)	145	0.85239	0.898	0.03805	0.146	0.02122	0.0861	0.00257	0.0148	0.0016	0.0123	0.00195	0.0129
NPM1	33 (17%)	160	0.0037	0.0196	0.00013	0.00224	9.9999e-06	0.000197	9.9999e-06	0.000197	9.9999e-06	0.000197	9.9999e-06	0.000197
IDH2	20 (10%)	173	0.10165	0.295	0.01711	0.0716	0.68359	0.786	0.34335	0.585	0.75841	0.83	0.18532	0.433
IDH1	18 (9%)	175	1	1	0.00487	0.024	0.27382	0.497	0.26475	0.487	0.23884	0.485	0.80522	0.855
TET2	17 (9%)	176	0.35788	0.588	0.45206	0.663	0.3108	0.55	0.58027	0.737	0.64192	0.764	0.75447	0.83
NRAS	15 (8%)	178	0.42579	0.639	0.94771	0.983	0.55768	0.737	0.92635	0.968	0.78616	0.842	0.58433	0.737
WT1	12 (6%)	181	0.42269	0.639	0.00329	0.0182	0.075509	0.237	0.37156	0.589	0.071569	0.237	0.25095	0.487
U2AF1	8 (4%)	185	1	1	0.061039	0.211	0.23256	0.485	0.26194	0.487	0.075919	0.237	0.47632	0.679
RUNX1	16 (8%)	177	0.5904	0.737	0.0039	0.0199	0.0086899	0.04	0.00025	0.00287	0.00172	0.0125	0.00236	0.0142
CEBPA	13 (7%)	180	0.59845	0.737	0.43404	0.644	0.21176	0.471	0.00019	0.00262	0.03939	0.147	0.01315	0.0585
TP53	15 (8%)	178	9.9999e-06	0.000197	9.9999e-06	0.000197	0.00089999	0.00771	0.00235	0.0142	0.00022	0.00276	0.00016	0.00245
KRAS	8 (4%)	185	0.077359	0.237	0.72695	0.819	0.32425	0.559	0.63302	0.76	0.25463	0.487	0.68172	0.786
PHF6	6 (3%)	187	1	1	0.63101	0.76	0.72976	0.819	0.47737	0.679	0.7261	0.819	0.34919	0.588
STAG2	6 (3%)	187	0.56592	0.737	0.17912	0.433	0.12919	0.355	0.02717	0.107	0.68293	0.786	0.04845	0.171
KIT	8 (4%)	185	0.10414	0.295	0.01396	0.0602	0.32287	0.559	0.0061699	0.0294	0.36746	0.589	0.22081	0.484
RAD21	5 (3%)	188	0.48443	0.682	0.36069	0.588	0.60215	0.737	0.18035	0.433	0.19826	0.452	0.60338	0.737
EZH2	3 (2%)	190	0.10459	0.295	NA	NA	0.26084	0.487	0.59276	0.737	0.15915	0.411	0.42069	0.639
SMC3	7 (4%)	186	1	1	0.19986	0.452	0.554	0.737	0.4561	0.663	0.23105	0.485	0.36248	0.588
ASXL1	5 (3%)	188	0.74042	0.824	0.075599	0.237	0.25941	0.487	0.59583	0.737	0.161	0.411	0.42049	0.639
SMC1A	6 (3%)	187	0.76342	0.83	0.13111	0.355	0.5714	0.737	0.22763	0.485	0.16419	0.412	0.57716	0.737
PTPN11	9 (5%)	184	0.6827	0.786	0.42356	0.639	0.04778	0.171	0.50633	0.706	0.083759	0.251	0.18491	0.433
SUZ12	3 (2%)	190	0.29275	0.525	0.78664	0.842	0.2582	0.487	0.59394	0.737	0.23921	0.485	0.13794	0.366