Clinical Features	Time to Death		YEARS_TO_BIRTH		GENDER		RADIATION_THERAPY		KARNOFSKY_PERFORMANCE_SCORE		HISTOLOGICAL_TYPE		RACE		ETHNICITY	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
IDH1	397 (78%)	115	1.1102e-16	7.46e-14	9.3811e-09	1.05e-06	1	1	0.0089458	0.215	0.002516	0.0769	0.0051299	0.138	0.02535	0.437	1	1
TP53	247 (48%)	265	0.05401	0.637	2.4689e-12	5.53e-10	0.28585	0.927	0.00016846	0.00708	0.27939	0.922	9.9999e-06	0.000611	0.03479	0.557	0.71481	1
ATRX	194 (38%)	318	0.088619	0.659	1.9692e-12	5.53e-10	0.78369	1	0.015577	0.317	0.79666	1	9.9999e-06	0.000611	0.43619	0.99	1	1
CIC	108 (21%)	404	0.00013564	0.00608	0.10745	0.72	0.32782	0.93	3.4586e-06	0.000332	0.23987	0.888	9.9999e-06	0.000611	0.75135	1	0.65645	1
NOTCH1	42 (8%)	470	0.12026	0.722	0.042354	0.574	0.74712	1	0.39231	0.952	0.86857	1	5e-05	0.0028	0.33583	0.931	1	1
IDH2	20 (4%)	492	0.059441	0.655	0.074031	0.659	1	1	0.47731	1	0.62068	1	0.00064999	0.0243	0.44992	0.999	0.12683	0.744
PIK3R1	22 (4%)	490	0.25902	0.888	0.079936	0.659	0.27452	0.913	0.48687	1	0.52169	1	0.35426	0.931	0.04555	0.598	0.62325	1
FUBP1	47 (9%)	465	0.12972	0.751	0.003014	0.0881	0.64464	1	0.069509	0.659	0.23608	0.888	9.9999e-06	0.000611	1	1	0.10029	0.702
NF1	33 (6%)	479	9.9515e-05	0.00514	0.012499	0.28	0.58967	1	0.45436	1	0.5485	1	0.01555	0.317	0.22071	0.883	0.25787	0.888
ARID1A	20 (4%)	492	0.03795	0.559	0.64848	1	0.49271	1	0.35146	0.931	0.96377	1	0.19528	0.836	1	1	1	1
PTEN	24 (5%)	488	0.00012976	0.00608	0.0017624	0.0623	0.29672	0.93	0.067138	0.659	0.58456	1	0.00245	0.0769	0.16275	0.787	1	1
EGFR	35 (7%)	477	1.2332e-11	2.07e-09	4.8386e-11	6.5e-09	1	1	0.014756	0.317	0.0049541	0.138	0.04837	0.608	0.18081	0.81	0.71757	1
GAGE2A	8 (2%)	504	0.50744	1	0.73266	1	0.7366	1	1	1	0.32282	0.93	1	1	0.053979	0.637	0.42798	0.978
NUDT11	11 (2%)	501	0.5249	1	0.32111	0.93	0.3599	0.941	1	1	0.64118	1	0.74475	1	1	1	1	1
PIK3CA	44 (9%)	468	0.65027	1	0.072862	0.659	0.87502	1	0.2561	0.888	0.10175	0.705	0.0182	0.34	0.62789	1	0.74256	1
STK19	10 (2%)	502	0.30684	0.93	0.31077	0.93	0.11982	0.722	0.68234	1	0.22991	0.888	0.075439	0.659	1	1	0.13958	0.769
EMG1	6 (1%)	506	0.53743	1	0.098145	0.694	0.41498	0.952	1	1	0.36576	0.948	0.35108	0.931	1	1	1	1
SMARCA4	26 (5%)	486	0.0071534	0.185	0.52333	1	0.31785	0.93	1	1	0.43213	0.984	0.78957	1	0.11505	0.72	0.64363	1
NIPBL	18 (4%)	494	0.057836	0.654	0.17614	0.803	0.15605	0.787	0.311	0.93	0.6044	1	0.069709	0.659	0.075619	0.659	0.11177	0.72
TCF12	15 (3%)	497	0.62474	1	0.22495	0.888	0.60092	1	1	1	0.91463	1	0.89536	1	1	1	0.6133	1
DNMT3A	10 (2%)	502	0.036435	0.559	0.47927	1	1	1	0.74703	1	0.99221	1	0.33697	0.931	0.4618	1	0.5033	1
TRERF1	6 (1%)	506	0.48187	1	0.28476	0.927	0.094062	0.672	0.68234	1	0.79787	1	0.16709	0.787	1	1	1	1
CREBZF	7 (1%)	505	0.95517	1	0.17099	0.787	0.25117	0.888	1	1	0.069895	0.659	0.03145	0.515	0.34992	0.931	0.38628	0.948
FAM47C	18 (4%)	494	0.077456	0.659	0.56223	1	0.47011	1	0.45992	1	0.64925	1	0.59465	1	1	1	1	1
MYST4	11 (2%)	501	0.092173	0.666	0.10839	0.72	1	1	1	1	0.92789	1	0.18922	0.831	0.14681	0.787	0.5033	1
MED9	3 (1%)	509	0.2301	0.888	0.87068	1	0.25689	0.888	0.28484	0.927	NA	NA	0.01618	0.32	1	1	1	1
IRS4	7 (1%)	505	0.16023	0.787	0.49528	1	1	1	1	1	0.66372	1	0.13728	0.769	1	1	0.38628	0.948
HTRA2	5 (1%)	507	0.33936	0.931	0.027938	0.469	1	1	0.38994	0.952	NA	NA	0.45056	0.999	1	1	0.29388	0.927
NRAS	4 (1%)	508	0.28002	0.922	0.88305	1	1	1	0.64505	1	0.47096	1	0.02297	0.406	1	1	1	1
TNRC18	9 (2%)	503	0.32087	0.93	0.94823	1	0.19777	0.841	0.49286	1	0.91501	1	0.15097	0.787	1	1	1	1
ZNF709	4 (1%)	508	0.08419	0.659	0.5946	1	0.13189	0.751	1	1	NA	NA	0.13942	0.769	0.22046	0.883	0.24276	0.888
PLXNA3	9 (2%)	503	0.09074	0.663	0.24852	0.888	0.31066	0.93	0.15776	0.787	0.5881	1	0.83433	1	0.10943	0.72	1	1
ROBO3	5 (1%)	507	0.48984	1	0.53254	1	0.66063	1	0.64505	1	0.66372	1	0.37765	0.948	1	1	0.29388	0.927
RB1	6 (1%)	506	0.82863	1	0.16464	0.787	0.41498	0.952	1	1	NA	NA	0.080669	0.659	0.31481	0.93	1	1
SRPX	4 (1%)	508	0.15062	0.787	0.042691	0.574	0.039439	0.561	1	1	0.55488	1	0.37724	0.948	0.21955	0.883	1	1
PDGFRA	10 (2%)	502	0.074082	0.659	0.70658	1	0.35412	0.931	0.74703	1	0.14194	0.775	0.11536	0.72	1	1	0.13958	0.769
ZNF512B	5 (1%)	507	0.080041	0.659	0.3006	0.93	1	1	1	1	NA	NA	1	1	1	1	0.29388	0.927
ZMIZ1	9 (2%)	503	0.071168	0.659	0.86164	1	0.52231	1	1	1	0.14892	0.787	0.44037	0.99	0.066059	0.659	0.017407	0.334
TMEM216	3 (1%)	509	0.77121	1	0.81697	1	0.088825	0.659	1	1	NA	NA	0.36718	0.948	1	1	1	1
ARID2	11 (2%)	501	0.50987	1	0.10862	0.72	1	1	0.215	0.883	0.80697	1	0.20568	0.864	0.24407	0.888	1	1
RBPJ	7 (1%)	505	0.87327	1	0.053793	0.637	1	1	0.68234	1	0.33462	0.931	0.27433	0.913	1	1	1	1
CUL4B	10 (2%)	502	0.21138	0.882	0.82366	1	0.11982	0.722	0.32873	0.93	0.64118	1	0.33511	0.931	0.21919	0.883	1	1
SLC6A3	9 (2%)	503	0.64171	1	0.37732	0.948	0.52231	1	1	1	NA	NA	0.76126	1	1	1	0.38628	0.948
SETD2	10 (2%)	502	0.55957	1	0.007939	0.198	1	1	0.74703	1	0.30813	0.93	0.36246	0.944	0.46558	1	1	1
KRT3	4 (1%)	508	0.088298	0.659	0.85564	1	0.63189	1	1	1	0.10516	0.72	0.68413	1	1	1	0.24276	0.888
MYT1	6 (1%)	506	0.26764	0.899	0.40787	0.952	1	1	0.086121	0.659	0.73425	1	0.16988	0.787	1	1	1	1
SMOC1	3 (1%)	509	0.48943	1	0.44314	0.993	1	1	0.52323	1	0.97809	1	0.47485	1	1	1	1	1
ZBTB20	21 (4%)	491	0.22869	0.888	0.49549	1	0.37144	0.948	0.1612	0.787	0.79781	1	0.18207	0.81	0.12734	0.744	0.63596	1
PPL	6 (1%)	506	0.040076	0.561	0.72698	1	1	1	1	1	0.79787	1	0.40148	0.952	1	1	0.29388	0.927
PTPN11	7 (1%)	505	0.25302	0.888	0.34208	0.931	1	1	1	1	0.75474	1	0.30934	0.93	0.35448	0.931	1	1
RET	7 (1%)	505	0.65114	1	0.50018	1	0.25117	0.888	0.43946	0.99	0.6002	1	0.072439	0.659	1	1	1	1
ANKRD36	7 (1%)	505	0.089219	0.659	0.59267	1	0.70572	1	0.046309	0.598	0.069895	0.659	0.23661	0.888	0.069779	0.659	1	1
NEU2	5 (1%)	507	0.22684	0.888	0.16784	0.787	1	1	1	1	NA	NA	0.37992	0.948	1	1	0.29388	0.927
PRX	10 (2%)	502	0.76068	1	0.46263	1	0.35412	0.931	0.32873	0.93	0.32952	0.93	0.7814	1	1	1	0.5033	1
RBBP6	6 (1%)	506	0.19536	0.836	0.32062	0.93	1	1	0.68234	1	NA	NA	0.77336	1	0.12451	0.74	1	1
CIB1	4 (1%)	508	0.40729	0.952	1	1	1	1	1	1	0.75474	1	1	1	1	1	1	1
DDX5	5 (1%)	507	0.11408	0.72	0.85386	1	1	1	1	1	0.28879	0.927	0.85158	1	1	1	0.24276	0.888
NAP1L2	4 (1%)	508	0.26665	0.899	0.17756	0.803	1	1	0.64505	1	NA	NA	0.1954	0.836	1	1	1	1
SCN4A	6 (1%)	506	0.18711	0.827	0.26045	0.888	0.41498	0.952	0.68234	1	0.33313	0.931	0.77451	1	1	1	1	1
AGBL1	5 (1%)	507	0.25355	0.888	0.20261	0.856	0.38648	0.948	1	1	NA	NA	0.19217	0.836	1	1	1	1
TPX2	5 (1%)	507	0.23303	0.888	0.983	1	0.66063	1	1	1	NA	NA	1	1	1	1	0.038271	0.559
KRT15	6 (1%)	506	0.7508	1	0.11566	0.72	0.69611	1	0.21463	0.883	0.40971	0.952	0.88599	1	0.31261	0.93	1	1
HTR3A	7 (1%)	505	0.403	0.952	0.54032	1	0.048857	0.608	0.43946	0.99	0.079391	0.659	0.89992	1	0.0092699	0.215	1	1
C14ORF4	3 (1%)	509	0.46681	1	0.73881	1	0.5891	1	1	1	NA	NA	0.78635	1	0.16964	0.787	1	1
R3HDM1	7 (1%)	505	0.058355	0.654	0.87198	1	1	1	1	1	0.75474	1	0.49433	1	1	1	0.38628	0.948
G6PC	6 (1%)	506	0.87793	1	0.40081	0.952	0.69611	1	0.41175	0.952	0.50982	1	0.40322	0.952	1	1	0.055023	0.638
DLC1	6 (1%)	506	0.56149	1	0.55254	1	0.41498	0.952	0.086121	0.659	NA	NA	0.66638	1	1	1	0.34165	0.931
SLC12A7	7 (1%)	505	0.17812	0.803	0.54032	1	0.70572	1	0.41175	0.952	0.52024	1	1	1	0.35034	0.931	1	1
SMARCB1	4 (1%)	508	0.31167	0.93	0.81053	1	0.63189	1	0.16006	0.787	0.75474	1	1	1	1	1	1	1
WRN	5 (1%)	507	0.084164	0.659	0.38058	0.948	0.66063	1	1	1	0.037929	0.559	0.55186	1	0.26602	0.899	0.0024969	0.0769
LAMA4	4 (1%)	508	0.79618	1	0.35355	0.931	0.13189	0.751	1	1	0.75474	1	0.066669	0.659	0.079549	0.659	0.24276	0.888
MAST2	5 (1%)	507	0.47167	1	0.70465	1	0.66063	1	0.16181	0.787	NA	NA	0.45015	0.999	1	1	1	1
ZMYM2	7 (1%)	505	0.15318	0.787	0.69991	1	1	1	0.25547	0.888	0.66372	1	1	1	1	1	0.38628	0.948
SLFN11	4 (1%)	508	0.11403	0.72	0.08624	0.659	0.63189	1	0.64505	1	NA	NA	0.56688	1	1	1	0.24276	0.888
C4BPA	6 (1%)	506	0.5277	1	0.64023	1	0.41498	0.952	0.41175	0.952	0.16615	0.787	0.88453	1	0.30682	0.93	0.34165	0.931
TMEM184A	3 (1%)	509	0.00052473	0.0207	0.15108	0.787	1	1	1	1	NA	NA	1	1	0.16988	0.787	1	1
KTELC1	5 (1%)	507	0.31163	0.93	0.65998	1	0.38648	0.948	0.65293	1	NA	NA	0.85151	1	1	1	1	1
ASXL2	3 (1%)	509	0.1196	0.722	0.41342	0.952	0.5891	1	1	1	NA	NA	0.62697	1	1	1	1	1
CCDC135	7 (1%)	505	0.23637	0.888	0.75703	1	0.25117	0.888	1	1	NA	NA	0.70605	1	1	1	0.38628	0.948
SLC25A5	4 (1%)	508	0.022868	0.406	0.57938	1	0.32944	0.93	1	1	0.25036	0.888	0.83749	1	0.22081	0.883	1	1
ABCA7	9 (2%)	503	0.7521	1	0.16255	0.787	0.73754	1	1	1	0.55903	1	0.53414	1	1	1	1	1
NKD2	4 (1%)	508	0.98858	1	0.68697	1	1	1	0.30423	0.93	NA	NA	0.45627	1	1	1	1	1
MAX	4 (1%)	508	0.80132	1	0.16635	0.787	0.32944	0.93	0.56338	1	0.97809	1	0.83766	1	1	1	1	1
VSIG4	6 (1%)	506	0.9146	1	0.94566	1	0.41498	0.952	1	1	NA	NA	1	1	1	1	1	1