Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.063 0.149 0.4 81.0 -9999.0 0.0 81.0 KIRREL -0.037 0.164 -9999.0 0.0 -0.594 41.0 41.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.063 0.15 -9999.0 0.0 -0.4 81.0 81.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.046 0.108 -9999.0 0.0 -0.337 42.0 42.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.004 0.096 -9999.0 0.0 -0.287 42.0 42.0 FYN -0.024 0.109 -9999.0 0.0 -0.321 42.0 42.0 mol:Ca2+ -0.045 0.108 -9999.0 0.0 -0.334 42.0 42.0 mol:DAG -0.045 0.108 -9999.0 0.0 -0.335 42.0 42.0 NPHS2 -0.006 0.039 -9999.0 0.0 -0.537 2.0 2.0 mol:IP3 -0.045 0.108 -9999.0 0.0 -0.335 42.0 42.0 regulation of endocytosis -0.015 0.103 -9999.0 0.0 -0.295 42.0 42.0 Nephrin/NEPH1/podocin/Cholesterol -0.047 0.112 -9999.0 0.0 -0.293 83.0 83.0 establishment of cell polarity -0.063 0.149 -9999.0 0.0 -0.4 81.0 81.0 Nephrin/NEPH1/podocin/NCK1-2 -0.041 0.099 -9999.0 0.0 -0.312 38.0 38.0 Nephrin/NEPH1/beta Arrestin2 -0.014 0.104 -9999.0 0.0 -0.299 42.0 42.0 NPHS1 -0.035 0.141 -9999.0 0.0 -0.494 44.0 44.0 Nephrin/NEPH1/podocin -0.027 0.109 -9999.0 0.0 -0.323 42.0 42.0 TJP1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.027 -9999.0 0.0 -0.593 1.0 1.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.046 0.108 -9999.0 0.0 -0.337 42.0 42.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.046 0.109 -9999.0 0.0 -0.335 43.0 43.0 GRB2 0.013 0.022 -9999.0 0.0 -0.489 1.0 1.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.043 0.134 -9999.0 0.0 -0.312 79.0 79.0 cytoskeleton organization -0.004 0.111 -9999.0 0.0 -0.327 42.0 42.0 Nephrin/NEPH1 -0.045 0.107 -9999.0 0.0 -0.283 81.0 81.0 Nephrin/NEPH1/ZO-1 -0.049 0.117 -9999.0 0.0 -0.311 81.0 81.0