Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.003 0.095 0.318 38.0 -9999.0 0.0 38.0 KIRREL -0.009 0.121 -9999.0 0.0 -0.434 38.0 38.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.003 0.095 -9999.0 0.0 -0.318 38.0 38.0 PLCG1 0.025 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.02 0.011 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.029 0.08 -9999.0 0.0 -0.237 38.0 38.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.003 0.069 -9999.0 0.0 -0.245 32.0 32.0 FYN -0.009 0.076 0.181 22.0 -0.225 39.0 61.0 mol:Ca2+ 0.026 0.08 -9999.0 0.0 -0.235 39.0 39.0 mol:DAG 0.027 0.081 -9999.0 0.0 -0.236 39.0 39.0 NPHS2 0.001 0.033 -9999.0 0.0 -0.283 2.0 2.0 mol:IP3 0.027 0.081 -9999.0 0.0 -0.236 39.0 39.0 regulation of endocytosis 0.023 0.072 -9999.0 0.0 -0.214 39.0 39.0 Nephrin/NEPH1/podocin/Cholesterol 0.016 0.075 -9999.0 0.0 -0.234 39.0 39.0 establishment of cell polarity -0.003 0.095 -9999.0 0.0 -0.318 38.0 38.0 Nephrin/NEPH1/podocin/NCK1-2 0.04 0.082 -9999.0 0.0 -0.222 38.0 38.0 Nephrin/NEPH1/beta Arrestin2 0.025 0.074 -9999.0 0.0 -0.216 39.0 39.0 NPHS1 -0.001 0.053 -9999.0 0.0 -0.262 6.0 6.0 Nephrin/NEPH1/podocin 0.018 0.073 -9999.0 0.0 -0.226 39.0 39.0 TJP1 0.026 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.025 0.02 -9999.0 0.0 -0.428 1.0 1.0 NCK2 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.028 0.081 -9999.0 0.0 -0.237 39.0 39.0 CD2AP 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.027 0.08 -9999.0 0.0 -0.237 38.0 38.0 GRB2 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.014 0.086 0.188 26.0 -0.233 46.0 72.0 cytoskeleton organization -0.017 0.083 0.203 12.0 -0.269 32.0 44.0 Nephrin/NEPH1 0.009 0.067 -9999.0 0.0 -0.218 38.0 38.0 Nephrin/NEPH1/ZO-1 0.021 0.081 -9999.0 0.0 -0.252 38.0 38.0