Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
TP53	62 (31%)	136	0.0061499	0.0579	0.92668	0.957	9.9999e-06	0.00032	0.02155	0.128	0.01714	0.126	0.00117	0.0156	0.23226	0.494	0.0247	0.141
CTNNB1	51 (26%)	147	0.03872	0.194	0.00092999	0.0135	9.9999e-06	0.00032	9.9999e-06	0.00032	0.04506	0.205	9.9999e-06	0.00032	5e-04	0.00889	9.9999e-06	0.00032
RB1	15 (8%)	183	0.72833	0.873	0.00084999	0.0135	0.0056499	0.0579	0.31048	0.528	0.21419	0.476	0.39092	0.632	0.2135	0.476	0.3038	0.523
ARID1A	17 (9%)	181	0.84502	0.92	0.16443	0.404	0.10034	0.336	0.04605	0.205	0.12367	0.378	0.6284	0.811	0.01737	0.126	0.65553	0.832
AXIN1	9 (5%)	189	0.27885	0.51	0.47574	0.716	0.01066	0.0925	0.18697	0.434	0.00471	0.0538	0.45757	0.704	0.0058799	0.0579	0.69513	0.856
BAP1	11 (6%)	187	0.7894	0.903	0.00392	0.0482	0.00038	0.0076	0.00012	0.00274	2e-05	0.000533	0.053199	0.23	0.01641	0.126	0.04337	0.204
ALB	18 (9%)	180	0.041	0.199	0.02102	0.128	0.40551	0.649	0.57492	0.78	0.82096	0.906	0.84264	0.92	0.50433	0.722	0.25107	0.508
TSC2	9 (5%)	189	0.90559	0.947	0.01869	0.128	0.10095	0.336	0.01986	0.128	0.76474	0.9	0.56595	0.774	0.78588	0.903	0.11049	0.347
IL6ST	7 (4%)	191	0.49099	0.721	0.29872	0.52	0.16669	0.404	0.13721	0.383	0.43868	0.688	0.10547	0.338	0.47883	0.716	1	1
APOB	25 (13%)	173	0.96043	0.979	0.89252	0.939	0.13876	0.383	0.13255	0.379	0.15911	0.404	0.072989	0.285	0.29655	0.52	0.02562	0.141
PTEN	7 (4%)	191	0.48914	0.721	0.26404	0.509	0.37158	0.619	0.50547	0.722	0.85944	0.929	0.27631	0.51	0.78391	0.903	0.28464	0.51
EEF1A1	5 (3%)	193	0.055689	0.234	0.73362	0.873	0.25399	0.508	0.1325	0.379	0.61115	0.809	0.25972	0.509	0.23795	0.494	0.61659	0.809
KIF19	10 (5%)	188	0.91771	0.953	0.10268	0.336	0.23367	0.494	0.23615	0.494	0.38177	0.63	0.80961	0.906	0.15254	0.4	0.10116	0.336
THADA	6 (3%)	192	0.14169	0.384	0.13126	0.379	0.056929	0.234	0.20161	0.461	0.88906	0.939	0.62226	0.809	0.12507	0.378	0.54729	0.761
PRKDC	11 (6%)	187	0.26396	0.509	0.28213	0.51	0.50202	0.722	0.6761	0.845	0.02864	0.153	0.28709	0.51	0.27547	0.51	0.10304	0.336
HNF1A	8 (4%)	190	0.16544	0.404	0.66409	0.837	0.072419	0.285	0.5301	0.744	0.095299	0.336	0.15186	0.4	0.01098	0.0925	0.28414	0.51
F5	4 (2%)	194	0.81964	0.906	0.17892	0.421	0.7991	0.904	0.61939	0.809	0.10159	0.336	0.93748	0.962	NA	NA	NA	NA
GNAS	7 (4%)	191	0.88921	0.939	0.23761	0.494	0.03054	0.158	0.17015	0.406	0.076579	0.292	0.44972	0.699	0.55361	0.764	0.72444	0.873
MLL4	10 (5%)	188	0.41479	0.657	0.16323	0.404	0.51638	0.731	0.88239	0.939	0.62219	0.809	0.39134	0.632	0.68803	0.853	0.79015	0.903
HIST1H1C	5 (3%)	193	0.72201	0.873	0.73699	0.873	0.47087	0.716	0.34941	0.588	0.80203	0.904	0.24821	0.508	0.6389	0.818	0.02068	0.128