Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.017 0.168 -9999.0 0.0 -0.46 6.0 6.0 MAP3K8 0.019 0.057 -9999.0 0.0 -0.5 1.0 1.0 FOS -0.006 0.132 -9999.0 0.0 -0.471 3.0 3.0 PRKCA 0.01 0.08 -9999.0 0.0 -0.499 2.0 2.0 PTPN7 0.013 0.045 -9999.0 0.0 -0.249 2.0 2.0 HRAS 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.005 0.078 -9999.0 0.0 -0.322 4.0 4.0 NRAS 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.045 0.023 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.024 0.058 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K1 -0.001 0.113 -9999.0 0.0 -0.448 4.0 4.0 ELK1 0.021 0.021 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.003 0.083 -9999.0 0.0 -0.364 4.0 4.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.004 21.0 21.0 MAPK1 -0.028 0.158 -9999.0 0.0 -0.429 9.0 9.0 RAF1 -0.005 0.087 -9999.0 0.0 -0.364 4.0 4.0 KRAS 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0