Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.011 0.071 0.252 19.0 -9999.0 0.0 19.0 KIRREL 0.025 0.022 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.011 0.071 -9999.0 0.0 -0.253 19.0 19.0 PLCG1 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.039 0.064 -9999.0 0.0 -0.189 18.0 18.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.006 0.059 -9999.0 0.0 -0.214 18.0 18.0 FYN 0.004 0.072 0.155 32.0 -0.184 15.0 47.0 mol:Ca2+ 0.035 0.064 -9999.0 0.0 -0.189 19.0 19.0 mol:DAG 0.037 0.065 -9999.0 0.0 -0.189 19.0 19.0 NPHS2 -0.003 0.028 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.037 0.065 -9999.0 0.0 -0.189 19.0 19.0 regulation of endocytosis 0.033 0.06 -9999.0 0.0 -0.173 19.0 19.0 Nephrin/NEPH1/podocin/Cholesterol 0.025 0.059 -9999.0 0.0 -0.184 19.0 19.0 establishment of cell polarity 0.011 0.071 -9999.0 0.0 -0.252 19.0 19.0 Nephrin/NEPH1/podocin/NCK1-2 0.051 0.066 -9999.0 0.0 -0.177 18.0 18.0 Nephrin/NEPH1/beta Arrestin2 0.035 0.061 -9999.0 0.0 -0.174 19.0 19.0 NPHS1 -0.012 0.093 -9999.0 0.0 -0.351 20.0 20.0 Nephrin/NEPH1/podocin 0.026 0.059 -9999.0 0.0 -0.175 21.0 21.0 TJP1 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.038 0.065 -9999.0 0.0 -0.19 19.0 19.0 CD2AP 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.039 0.065 -9999.0 0.0 -0.189 19.0 19.0 GRB2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.001 0.08 0.159 32.0 -0.181 23.0 55.0 cytoskeleton organization -0.017 0.069 0.194 3.0 -0.26 18.0 21.0 Nephrin/NEPH1 0.012 0.05 -9999.0 0.0 -0.169 19.0 19.0 Nephrin/NEPH1/ZO-1 0.029 0.064 -9999.0 0.0 -0.2 19.0 19.0