Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.03 0.1 0.247 29.0 -9999.0 0.0 29.0 KIRREL -0.054 0.153 -9999.0 0.0 -0.401 29.0 29.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.03 0.1 -9999.0 0.0 -0.247 29.0 29.0 PLCG1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.014 0.074 -9999.0 0.0 -0.204 22.0 22.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.02 0.076 -9999.0 0.0 -0.21 22.0 22.0 FYN -0.008 0.08 -9999.0 0.0 -0.198 22.0 22.0 mol:Ca2+ -0.014 0.073 -9999.0 0.0 -0.203 22.0 22.0 mol:DAG -0.014 0.074 -9999.0 0.0 -0.204 22.0 22.0 NPHS2 -0.001 0.016 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.014 0.074 -9999.0 0.0 -0.204 22.0 22.0 regulation of endocytosis -0.011 0.068 -9999.0 0.0 -0.184 22.0 22.0 Nephrin/NEPH1/podocin/Cholesterol -0.019 0.072 -9999.0 0.0 -0.206 22.0 22.0 establishment of cell polarity -0.03 0.1 -9999.0 0.0 -0.247 29.0 29.0 Nephrin/NEPH1/podocin/NCK1-2 -0.007 0.069 -9999.0 0.0 -0.184 22.0 22.0 Nephrin/NEPH1/beta Arrestin2 -0.01 0.069 -9999.0 0.0 -0.186 22.0 22.0 NPHS1 0.002 0.015 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin -0.017 0.071 -9999.0 0.0 -0.198 22.0 22.0 TJP1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.014 0.074 -9999.0 0.0 -0.204 22.0 22.0 CD2AP 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.014 0.074 -9999.0 0.0 -0.204 22.0 22.0 GRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.006 0.076 -9999.0 0.0 -0.184 22.0 22.0 cytoskeleton organization -0.022 0.079 -9999.0 0.0 -0.22 22.0 22.0 Nephrin/NEPH1 -0.018 0.068 -9999.0 0.0 -0.195 22.0 22.0 Nephrin/NEPH1/ZO-1 -0.017 0.08 -9999.0 0.0 -0.222 22.0 22.0