Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.004	0.103	0.276	3.0	-0.443	20.0	23.0
IHH	0.042	0.059	0.232	32.0	-0.111	14.0	46.0
SHH Np/Cholesterol/GAS1	-0.006	0.069	0.109	37.0	-0.133	93.0	130.0
LRPAP1	0.025	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.006	0.068	0.132	93.0	-0.108	37.0	130.0
SMO/beta Arrestin2	0.012	0.092	-9999.0	0.0	-0.307	22.0	22.0
SMO	-0.003	0.081	-9999.0	0.0	-0.302	25.0	25.0
AKT1	-0.003	0.092	-9999.0	0.0	-0.36	16.0	16.0
ARRB2	0.024	0.007	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.024	0.006	-9999.0	0.0	-9999.0	0.0	0.0
ADRBK1	0.025	0.006	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.003	0.081	-9999.0	0.0	-0.299	25.0	25.0
STIL	-0.01	0.09	0.194	36.0	-0.254	19.0	55.0
DHH N/PTCH2	0.037	0.032	0.189	7.0	-0.161	8.0	15.0
DHH N/PTCH1	0.018	0.07	-9999.0	0.0	-0.211	34.0	34.0
PIK3CA	0.024	0.007	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.027	0.018	0.244	3.0	-9999.0	0.0	3.0
PTHLH	-0.008	0.135	0.352	2.0	-0.575	20.0	22.0
determination of left/right symmetry	-0.003	0.081	-9999.0	0.0	-0.299	25.0	25.0
PIK3R1	0.023	0.008	-9999.0	0.0	-9999.0	0.0	0.0
skeletal system development	-0.008	0.134	0.351	2.0	-0.57	20.0	22.0
IHH N/Hhip	0.022	0.09	0.168	32.0	-0.21	53.0	85.0
DHH N/Hhip	0.019	0.064	0.189	6.0	-0.161	51.0	57.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.003	0.081	-9999.0	0.0	-0.299	25.0	25.0
pancreas development	0.024	0.019	0.244	3.0	-9999.0	0.0	3.0
HHAT	0.024	0.006	-9999.0	0.0	-9999.0	0.0	0.0
PI3K	0.03	0.028	-9999.0	0.0	-0.182	6.0	6.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.023	0.014	0.244	1.0	-9999.0	0.0	1.0
somite specification	-0.003	0.081	-9999.0	0.0	-0.299	25.0	25.0
SHH Np/Cholesterol/PTCH1	-0.004	0.079	0.161	6.0	-0.227	29.0	35.0
SHH Np/Cholesterol/PTCH2	0.004	0.062	0.114	44.0	-0.125	70.0	114.0
SHH Np/Cholesterol/Megalin	-0.004	0.069	0.117	44.0	-0.129	90.0	134.0
SHH	0.0	0.046	0.144	43.0	-9999.0	0.0	43.0
catabolic process	0.005	0.072	0.193	1.0	-0.24	34.0	35.0
SMO/Vitamin D3	-0.005	0.088	0.284	2.0	-0.281	24.0	26.0
SHH Np/Cholesterol/Hhip	-0.005	0.074	0.112	43.0	-0.145	88.0	131.0
LRP2	0.026	0.031	0.244	9.0	-9999.0	0.0	9.0
receptor-mediated endocytosis	-0.019	0.093	0.234	1.0	-0.291	27.0	28.0
SHH Np/Cholesterol/BOC	0.002	0.061	0.108	41.0	-0.124	75.0	116.0
SHH Np/Cholesterol/CDO	0.005	0.059	0.11	44.0	-0.122	69.0	113.0
mesenchymal cell differentiation	0.005	0.074	0.144	88.0	-0.111	43.0	131.0
mol:Vitamin D3	0.005	0.091	0.194	26.0	-0.259	21.0	47.0
IHH N/PTCH2	0.039	0.059	0.173	33.0	-0.161	22.0	55.0
CDON	0.026	0.018	0.244	3.0	-9999.0	0.0	3.0
IHH N/PTCH1	0.019	0.081	0.263	3.0	-0.241	34.0	37.0
Megalin/LRPAP1	0.023	0.058	0.189	9.0	-0.16	39.0	48.0
PTCH2	0.027	0.02	0.244	4.0	-9999.0	0.0	4.0
SHH Np/Cholesterol	-0.019	0.047	0.072	43.0	-0.118	71.0	114.0
PTCH1	0.005	0.073	0.193	1.0	-0.24	34.0	35.0
HHIP	0.024	0.019	0.244	3.0	-9999.0	0.0	3.0