Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.045 0.172 0.332 1.0 -0.416 58.0 59.0 MAP3K8 0.02 0.018 0.244 1.0 -9999.0 0.0 1.0 FOS -0.037 0.138 0.239 2.0 -0.344 55.0 57.0 PRKCA 0.017 0.019 -9999.0 0.0 -0.039 1.0 1.0 PTPN7 0.026 0.052 0.244 22.0 -0.034 72.0 94.0 HRAS 0.028 0.025 0.244 6.0 -0.023 1.0 7.0 PRKCB 0.015 0.018 -9999.0 0.0 -0.032 2.0 2.0 NRAS 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.037 0.033 0.172 6.0 -9999.0 0.0 6.0 MAPK3 -0.009 0.091 -9999.0 0.0 -0.472 4.0 4.0 MAP2K1 -0.077 0.187 -9999.0 0.0 -0.39 107.0 107.0 ELK1 0.016 0.024 -9999.0 0.0 -0.04 40.0 40.0 BRAF -0.06 0.161 -9999.0 0.0 -0.369 89.0 89.0 mol:GTP -0.001 0.002 0.003 4.0 -0.004 84.0 88.0 MAPK1 -0.014 0.105 -9999.0 0.0 -0.45 12.0 12.0 RAF1 -0.067 0.165 -9999.0 0.0 -0.36 101.0 101.0 KRAS 0.024 0.008 -9999.0 0.0 -9999.0 0.0 0.0