Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.02 0.159 -9999.0 0.0 -0.602 7.0 7.0 MAP3K8 0.028 0.002 -9999.0 0.0 -9999.0 0.0 0.0 FOS -0.033 0.154 -9999.0 0.0 -0.623 7.0 7.0 PRKCA 0.026 0.009 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.008 0.093 -9999.0 0.0 -0.429 7.0 7.0 HRAS 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.073 0.173 -9999.0 0.0 -0.371 41.0 41.0 NRAS 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.045 0.032 -9999.0 0.0 -0.198 2.0 2.0 MAPK3 -0.013 0.123 -9999.0 0.0 -0.687 4.0 4.0 MAP2K1 -0.063 0.161 -9999.0 0.0 -0.35 34.0 34.0 ELK1 0.027 0.009 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.06 0.15 -9999.0 0.0 -0.337 34.0 34.0 mol:GTP 0.0 0.001 -9999.0 0.0 -0.005 3.0 3.0 MAPK1 -0.032 0.165 -9999.0 0.0 -0.576 11.0 11.0 RAF1 -0.065 0.159 -9999.0 0.0 -0.335 39.0 39.0 KRAS 0.021 0.044 -9999.0 0.0 -0.371 2.0 2.0