Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.164 0.219 0.42 105.0 -9999.0 0.0 105.0 KIRREL -0.012 0.076 0.232 11.0 -0.558 1.0 12.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.165 0.219 -9999.0 0.0 -0.421 105.0 105.0 PLCG1 0.018 0.004 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.018 0.005 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.018 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.137 0.205 -9999.0 0.0 -0.354 110.0 110.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.141 0.177 -9999.0 0.0 -0.326 111.0 111.0 FYN -0.145 0.187 0.251 5.0 -0.337 110.0 115.0 mol:Ca2+ -0.136 0.203 -9999.0 0.0 -0.353 109.0 109.0 mol:DAG -0.136 0.204 -9999.0 0.0 -0.355 109.0 109.0 NPHS2 -0.095 0.181 -9999.0 0.0 -0.578 30.0 30.0 mol:IP3 -0.136 0.204 -9999.0 0.0 -0.355 109.0 109.0 regulation of endocytosis -0.128 0.181 -9999.0 0.0 -0.322 108.0 108.0 Nephrin/NEPH1/podocin/Cholesterol -0.142 0.201 -9999.0 0.0 -0.35 113.0 113.0 establishment of cell polarity -0.164 0.219 -9999.0 0.0 -0.42 105.0 105.0 Nephrin/NEPH1/podocin/NCK1-2 -0.125 0.197 -9999.0 0.0 -0.329 113.0 113.0 Nephrin/NEPH1/beta Arrestin2 -0.128 0.184 -9999.0 0.0 -0.326 108.0 108.0 NPHS1 -0.243 0.273 -9999.0 0.0 -0.561 107.0 107.0 Nephrin/NEPH1/podocin -0.133 0.194 -9999.0 0.0 -0.338 110.0 110.0 TJP1 0.019 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.019 0.002 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.019 0.002 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.136 0.206 -9999.0 0.0 -0.357 109.0 109.0 CD2AP 0.018 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.136 0.204 -9999.0 0.0 -0.352 111.0 111.0 GRB2 0.019 0.003 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.14 0.182 0.243 6.0 -0.323 112.0 118.0 cytoskeleton organization -0.182 0.209 0.187 2.0 -0.403 109.0 111.0 Nephrin/NEPH1 -0.114 0.157 -9999.0 0.0 -0.298 105.0 105.0 Nephrin/NEPH1/ZO-1 -0.126 0.182 -9999.0 0.0 -0.342 102.0 102.0