Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.081 0.16 0.29 134.0 -9999.0 0.0 134.0 KIRREL 0.002 0.05 -9999.0 0.0 -0.408 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.081 0.16 -9999.0 0.0 -0.291 134.0 134.0 PLCG1 0.033 0.01 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.034 0.009 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.032 0.011 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.035 0.132 -9999.0 0.0 -0.216 122.0 122.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.058 0.116 -9999.0 0.0 -0.223 119.0 119.0 FYN -0.051 0.129 0.253 18.0 -0.205 133.0 151.0 mol:Ca2+ -0.036 0.13 -9999.0 0.0 -0.214 123.0 123.0 mol:DAG -0.036 0.131 -9999.0 0.0 -0.215 123.0 123.0 NPHS2 -0.009 0.037 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.036 0.131 -9999.0 0.0 -0.215 123.0 123.0 regulation of endocytosis -0.04 0.118 -9999.0 0.0 -0.193 132.0 132.0 Nephrin/NEPH1/podocin/Cholesterol -0.049 0.126 -9999.0 0.0 -0.213 133.0 133.0 establishment of cell polarity -0.081 0.16 -9999.0 0.0 -0.29 134.0 134.0 Nephrin/NEPH1/podocin/NCK1-2 -0.023 0.134 -9999.0 0.0 -0.197 131.0 131.0 Nephrin/NEPH1/beta Arrestin2 -0.039 0.12 -9999.0 0.0 -0.195 132.0 132.0 NPHS1 -0.13 0.209 -9999.0 0.0 -0.406 133.0 133.0 Nephrin/NEPH1/podocin -0.048 0.121 -9999.0 0.0 -0.206 133.0 133.0 TJP1 0.035 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.035 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.036 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.035 0.132 -9999.0 0.0 -0.215 123.0 123.0 CD2AP 0.032 0.025 -9999.0 0.0 -0.4 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 -0.037 0.136 -9999.0 0.0 -0.215 130.0 130.0 GRB2 0.035 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.052 0.122 0.251 23.0 -0.196 124.0 147.0 cytoskeleton organization -0.078 0.139 0.204 5.0 -0.276 117.0 122.0 Nephrin/NEPH1 -0.051 0.112 -9999.0 0.0 -0.197 134.0 134.0 Nephrin/NEPH1/ZO-1 -0.049 0.137 -9999.0 0.0 -0.228 133.0 133.0