Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.029 0.112 0.269 44.0 -9999.0 0.0 44.0 KIRREL 0.001 0.047 -9999.0 0.0 -0.356 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.029 0.113 -9999.0 0.0 -0.269 44.0 44.0 PLCG1 0.023 0.009 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.03 0.134 -9999.0 0.0 -0.237 61.0 61.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.046 0.108 -9999.0 0.0 -0.275 19.0 19.0 FYN -0.049 0.119 0.294 5.0 -0.226 61.0 66.0 mol:Ca2+ -0.029 0.125 -9999.0 0.0 -0.234 52.0 52.0 mol:DAG -0.029 0.126 -9999.0 0.0 -0.235 52.0 52.0 NPHS2 -0.072 0.173 -9999.0 0.0 -0.408 56.0 56.0 mol:IP3 -0.029 0.126 -9999.0 0.0 -0.235 52.0 52.0 regulation of endocytosis -0.031 0.117 -9999.0 0.0 -0.334 9.0 9.0 Nephrin/NEPH1/podocin/Cholesterol -0.041 0.127 -9999.0 0.0 -0.217 87.0 87.0 establishment of cell polarity -0.029 0.112 -9999.0 0.0 -0.269 44.0 44.0 Nephrin/NEPH1/podocin/NCK1-2 -0.019 0.13 -9999.0 0.0 -0.349 8.0 8.0 Nephrin/NEPH1/beta Arrestin2 -0.031 0.119 -9999.0 0.0 -0.338 9.0 9.0 NPHS1 -0.051 0.144 -9999.0 0.0 -0.371 44.0 44.0 Nephrin/NEPH1/podocin -0.037 0.122 -9999.0 0.0 -0.226 62.0 62.0 TJP1 0.026 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.026 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.026 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.028 0.127 -9999.0 0.0 -0.236 52.0 52.0 CD2AP 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.033 0.135 -9999.0 0.0 -0.237 62.0 62.0 GRB2 0.026 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.051 0.112 0.278 4.0 -0.28 16.0 20.0 cytoskeleton organization -0.06 0.12 0.212 3.0 -0.32 19.0 22.0 Nephrin/NEPH1 -0.015 0.078 -9999.0 0.0 -0.181 44.0 44.0 Nephrin/NEPH1/ZO-1 -0.009 0.096 -9999.0 0.0 -0.212 42.0 42.0