Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
FAM18B2	26 (18%)	121	0.70875	1	0.35673	0.968	0.7192	1	0.53	1	0.70218	1	0.49799	1	0.54205	1	0.45096	1	0.70038	1	0.85113	1
KIT	26 (18%)	121	0.00153	0.0531	0.00014	0.0059	9.9999e-06	0.00059	9.9999e-06	0.00059	9.9999e-06	0.00059	9.9999e-06	0.00059	9.9999e-06	0.00059	9.9999e-06	0.00059	9.9999e-06	0.00059	9.9999e-06	0.00059
KRAS	19 (13%)	128	0.0067299	0.173	0.00037	0.014	0.00389	0.121	0.00038	0.014	9.9999e-06	0.00059	0.00177	0.058	3e-05	0.00147	9.9999e-06	0.00059	2e-05	0.00107	4e-05	0.00182
FAM104B	7 (5%)	140	0.37686	0.968	0.49864	1	0.24939	0.962	0.71789	1	0.35446	0.968	0.26268	0.962	0.096129	0.683	0.25235	0.962	0.53864	1	0.54456	1
CSGALNACT2	5 (3%)	142	0.01263	0.248	0.1928	0.936	0.04615	0.489	0.02238	0.322	0.0084499	0.199	0.0112	0.236	0.03005	0.362	0.01503	0.269	0.02363	0.324	0.078829	0.643
NRAS	7 (5%)	140	0.052809	0.503	0.080689	0.643	0.15519	0.872	0.03559	0.389	0.01689	0.277	0.14578	0.852	0.01333	0.254	0.01682	0.277	0.070869	0.597	0.01162	0.236
DDX11	8 (5%)	139	1	1	0.27908	0.962	0.59017	1	0.14188	0.837	0.40862	1	0.36309	0.968	0.13258	0.82	0.29014	0.967	0.65253	1	0.10052	0.69
MUC6	15 (10%)	132	0.69556	1	0.62416	1	0.59284	1	0.070739	0.597	0.83534	1	0.96513	1	1	1	0.73497	1	0.77845	1	0.91707	1
PNPLA4	5 (3%)	142	0.51676	1	1	1	0.43973	1	0.72078	1	0.52374	1	0.55202	1	0.37351	0.968	0.44638	1	0.32063	0.968	0.47415	1
SERINC2	4 (3%)	143	0.46242	1	0.83386	1	0.16431	0.906	0.052199	0.503	0.81072	1	0.73786	1	1	1	0.58596	1	0.81221	1	0.84262	1
RHPN2	6 (4%)	141	0.8776	1	0.24942	0.962	0.78041	1	1	1	0.87925	1	0.92006	1	0.57634	1	1	1	1	1	0.85133	1
RBM10	5 (3%)	142	0.62073	1	0.27729	0.962	0.87735	1	0.71891	1	0.44741	1	0.71281	1	0.63348	1	0.59653	1	0.6007	1	0.55646	1
HSF4	6 (4%)	141	0.24721	0.962	0.2178	0.962	0.49748	1	1	1	0.42016	1	0.14061	0.837	0.20321	0.959	0.36911	0.968	0.27662	0.962	0.28178	0.962
CDC27	6 (4%)	141	0.03317	0.384	0.77483	1	0.21263	0.962	0.18373	0.936	0.17105	0.917	0.057899	0.534	0.32921	0.968	0.13525	0.823	0.16761	0.916	0.04917	0.499
MLLT3	4 (3%)	143	0.55746	1	0.83497	1	NA	NA	NA	NA	0.80922	1	0.27989	0.962	1	1	0.58435	1	0.46533	1	0.84514	1
ERC1	7 (5%)	140	0.88647	1	0.79478	1	0.90815	1	0.86433	1	1	1	0.56306	1	1	1	1	1	1	1	0.95404	1
MEF2A	3 (2%)	144	1	1	1	1	NA	NA	NA	NA	1	1	0.32803	0.968	1	1	1	1	1	1	0.89277	1
SP8	6 (4%)	141	0.089679	0.676	0.51633	1	0.076309	0.634	0.02085	0.315	0.01626	0.277	0.0066599	0.173	0.04643	0.489	0.02181	0.322	0.02425	0.325	0.087449	0.676
NAT10	4 (3%)	143	0.38346	0.968	1	1	0.86552	1	0.59877	1	1	1	0.2573	0.962	0.83013	1	1	1	1	1	0.49449	1
SPIN2A	3 (2%)	144	0.63191	1	1	1	NA	NA	NA	NA	1	1	0.37141	0.968	1	1	1	1	1	1	0.89109	1
DEK	5 (3%)	142	0.0345	0.384	0.8641	1	0.44066	1	0.27558	0.962	0.37928	0.968	0.01881	0.292	0.37606	0.968	0.31975	0.968	0.44179	1	0.15796	0.879
FANK1	4 (3%)	143	0.38871	0.968	0.83633	1	0.23934	0.962	0.59582	1	0.37799	0.968	0.70925	1	0.45395	1	0.27856	0.962	0.27234	0.962	0.19103	0.936
ANKRD11	7 (5%)	140	0.88757	1	0.080349	0.643	0.59222	1	0.65249	1	0.25746	0.962	0.84896	1	0.3338	0.968	0.28733	0.963	0.28044	0.962	0.37786	0.968
C22ORF43	3 (2%)	144	0.3752	0.968	1	1	0.051339	0.503	0.79727	1	1	1	0.73554	1	1	1	1	1	1	1	1	1
ATXN3	3 (2%)	144	0.77775	1	0.3006	0.968	0.21351	0.962	0.1004	0.69	0.15447	0.872	0.18157	0.936	0.49002	1	0.091539	0.676	0.092809	0.676	0.50446	1
TPTE2	5 (3%)	142	0.62022	1	0.22966	0.962	1	1	1	1	0.32068	0.968	0.6336	1	0.04948	0.499	0.38291	0.968	0.44337	1	0.42392	1
KRTAP10-10	5 (3%)	142	1	1	0.6234	1	0.76278	1	0.53294	1	0.4526	1	0.87037	1	0.1878	0.936	0.59897	1	0.60273	1	0.61639	1
ZNF680	3 (2%)	144	0.19182	0.936	0.64073	1	0.51329	1	0.23243	0.962	0.25068	0.962	0.85731	1	0.059729	0.536	0.34271	0.968	0.33044	0.968	0.16934	0.917
RAC1	4 (3%)	143	0.38593	0.968	0.3874	0.968	0.64347	1	1	1	0.59143	1	0.63535	1	0.31675	0.968	0.48387	1	0.36471	0.968	0.086939	0.676
NBPF10	7 (5%)	140	0.098999	0.69	0.89115	1	0.78601	1	1	1	0.32213	0.968	0.23111	0.962	0.49527	1	0.41696	1	0.42132	1	0.77222	1
FAM8A1	3 (2%)	144	0.4956	1	0.11	0.729	NA	NA	NA	NA	0.25031	0.962	0.51559	1	0.059989	0.536	0.3405	0.968	0.33068	0.968	0.02343	0.324
PSMD11	4 (3%)	143	0.066569	0.578	0.03424	0.384	0.3013	0.968	0.23171	0.962	0.19393	0.936	0.75184	1	0.317	0.968	0.19408	0.936	0.36719	0.968	0.13347	0.82
KRTAP1-1	3 (2%)	144	1	1	0.7778	1	NA	NA	NA	NA	0.79463	1	0.47132	1	0.77906	1	0.61714	1	0.6077	1	0.70197	1
OPLAH	4 (3%)	143	0.82592	1	0.54839	1	0.57468	1	0.79784	1	1	1	0.31237	0.968	0.55959	1	0.27956	0.962	1	1	0.5397	1
FAM101B	4 (3%)	143	1	1	0.6877	1	1	1	1	1	1	1	0.4983	1	1	1	1	1	1	1	1	1
MUC2	16 (11%)	131	0.40109	0.986	0.94585	1	0.56592	1	0.43046	1	0.51587	1	0.9852	1	0.5001	1	0.94323	1	0.79311	1	0.78931	1
HTT	3 (2%)	144	1	1	0.77565	1	NA	NA	NA	NA	0.7973	1	0.68049	1	0.62965	1	0.61534	1	0.60715	1	0.70437	1
EZH2	4 (3%)	143	0.82669	1	0.55372	1	NA	NA	NA	NA	0.37999	0.968	0.54525	1	0.55873	1	0.27775	0.962	0.2706	0.962	0.27772	0.962
PABPC3	4 (3%)	143	1	1	0.46311	1	NA	NA	NA	NA	0.28495	0.963	0.60973	1	0.19037	0.936	0.37983	0.968	0.57946	1	0.30569	0.968
CUX1	5 (3%)	142	0.73225	1	0.86385	1	0.86594	1	0.59694	1	0.72321	1	0.96228	1	0.62975	1	0.85286	1	0.85714	1	0.72128	1
DLC1	3 (2%)	144	0.28013	0.962	1	1	0.64325	1	1	1	0.79577	1	0.94961	1	0.63048	1	0.61573	1	0.60747	1	0.70465	1
STAB1	7 (5%)	140	0.88681	1	0.19506	0.936	0.35792	0.968	1	1	0.28694	0.963	0.49852	1	0.26093	0.962	0.19713	0.938	0.12355	0.784	0.206	0.96
NOTCH1	5 (3%)	142	0.61967	1	0.62482	1	0.21964	0.962	0.84332	1	0.38342	0.968	0.44668	1	0.37192	0.968	0.31956	0.968	0.20836	0.96	0.22857	0.962
AHDC1	4 (3%)	143	0.55767	1	0.0081099	0.199	0.03237	0.382	0.10964	0.729	0.00458	0.135	0.0266	0.349	0.0050399	0.142	0.0094999	0.216	0.01034	0.226	0.01473	0.269
EPAS1	5 (3%)	142	0.44364	1	0.8654	1	0.83307	1	0.68115	1	0.72595	1	0.7871	1	0.63303	1	0.85539	1	0.85722	1	0.72037	1
PIK3CD	4 (3%)	143	0.24242	0.962	0.2641	0.962	NA	NA	NA	NA	0.48278	1	0.36905	0.968	0.13781	0.83	0.69589	1	0.68919	1	0.10183	0.691
BCL11B	5 (3%)	142	0.51768	1	0.27808	0.962	0.52838	1	0.53555	1	0.32147	0.968	0.93486	1	0.52833	1	0.38255	0.968	0.44512	1	0.42383	1
KIAA0430	3 (2%)	144	0.27583	0.962	0.77522	1	NA	NA	NA	NA	0.79379	1	0.77454	1	0.63159	1	0.61679	1	0.6085	1	0.70532	1
MTIF3	3 (2%)	144	1	1	0.40113	0.986	1	1	1	1	0.62019	1	1	1	0.37167	0.968	0.79241	1	0.79608	1	0.79543	1
BTN2A2	3 (2%)	144	0.27987	0.962	1	1	NA	NA	NA	NA	0.62145	1	0.81362	1	0.36962	0.968	0.79794	1	0.79451	1	0.79548	1
C17ORF64	3 (2%)	144	1	1	0.39948	0.986	NA	NA	NA	NA	1	1	0.37105	0.968	1	1	1	1	0.45352	1	0.44817	1
RUNX2	4 (3%)	143	1	1	0.68627	1	0.86434	1	0.60157	1	1	1	1	1	0.83011	1	1	1	1	1	0.49401	1
SSBP3	3 (2%)	144	0.7789	1	0.29887	0.968	NA	NA	NA	NA	0.15447	0.872	0.057389	0.534	0.49209	1	0.092739	0.676	0.094019	0.676	0.50242	1
GSX2	4 (3%)	143	0.31066	0.968	0.3247	0.968	0.64666	1	0.02731	0.35	0.6998	1	0.24089	0.962	0.064879	0.571	0.15156	0.872	0.81086	1	0.78849	1
SP4	4 (3%)	143	0.30998	0.968	0.01872	0.292	NA	NA	NA	NA	0.04994	0.499	0.11338	0.73	0.25241	0.962	0.02889	0.355	0.02796	0.351	0.17328	0.921
PCMTD1	5 (3%)	142	0.091769	0.676	0.62179	1	0.454	1	0.53462	1	0.38126	0.968	0.44665	1	0.37399	0.968	0.32142	0.968	0.20797	0.96	0.32862	0.968
RBM3	3 (2%)	144	0.37309	0.968	0.77446	1	NA	NA	NA	NA	0.79374	1	0.9489	1	0.11171	0.73	0.61528	1	0.60978	1	0.13075	0.82
ZNF814	5 (3%)	142	0.86039	1	0.37656	0.968	0.93331	1	0.84196	1	1	1	0.25778	0.962	0.73934	1	1	1	1	1	0.21297	0.962
TTC38	4 (3%)	143	0.38737	0.968	0.11376	0.73	0.91442	1	0.19414	0.936	0.28214	0.962	0.8166	1	0.19178	0.936	0.37713	0.968	0.57528	1	0.25437	0.962