Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.09 0.192 0.379 36.0 -9999.0 0.0 36.0 KIRREL -0.127 0.244 -9999.0 0.0 -0.52 33.0 33.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.09 0.192 -9999.0 0.0 -0.38 36.0 36.0 PLCG1 0.032 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.031 0.009 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.031 0.009 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.048 0.159 -9999.0 0.0 -0.286 36.0 36.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.06 0.131 -9999.0 0.0 -0.256 36.0 36.0 FYN -0.052 0.161 0.297 8.0 -0.27 36.0 44.0 mol:Ca2+ -0.048 0.158 -9999.0 0.0 -0.284 36.0 36.0 mol:DAG -0.047 0.159 -9999.0 0.0 -0.285 36.0 36.0 NPHS2 -0.009 0.039 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.047 0.159 -9999.0 0.0 -0.285 36.0 36.0 regulation of endocytosis -0.044 0.142 -9999.0 0.0 -0.256 36.0 36.0 Nephrin/NEPH1/podocin/Cholesterol -0.058 0.15 -9999.0 0.0 -0.283 36.0 36.0 establishment of cell polarity -0.09 0.192 -9999.0 0.0 -0.379 36.0 36.0 Nephrin/NEPH1/podocin/NCK1-2 -0.035 0.16 -9999.0 0.0 -0.27 36.0 36.0 Nephrin/NEPH1/beta Arrestin2 -0.043 0.144 -9999.0 0.0 -0.258 36.0 36.0 NPHS1 -0.014 0.114 -9999.0 0.0 -0.467 6.0 6.0 Nephrin/NEPH1/podocin -0.053 0.145 -9999.0 0.0 -0.271 36.0 36.0 TJP1 0.032 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.05 -9999.0 0.0 -0.513 1.0 1.0 NCK2 0.033 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.047 0.16 -9999.0 0.0 -0.286 36.0 36.0 CD2AP 0.03 0.01 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.047 0.158 -9999.0 0.0 -0.286 35.0 35.0 GRB2 0.031 0.009 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.057 0.156 0.329 6.0 -0.262 37.0 43.0 cytoskeleton organization -0.076 0.148 0.206 2.0 -0.298 35.0 37.0 Nephrin/NEPH1 -0.061 0.137 -9999.0 0.0 -0.265 36.0 36.0 Nephrin/NEPH1/ZO-1 -0.058 0.164 -9999.0 0.0 -0.304 36.0 36.0