Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.187 0.273 -9999.0 0.0 -0.383 67.0 67.0 MAP3K8 0.028 0.008 -9999.0 0.0 -9999.0 0.0 0.0 FOS -0.114 0.225 -9999.0 0.0 -0.601 15.0 15.0 PRKCA 0.005 0.028 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 -0.037 0.132 -9999.0 0.0 -0.518 8.0 8.0 HRAS 0.029 0.009 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.04 0.146 -9999.0 0.0 -0.515 10.0 10.0 NRAS 0.03 0.007 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.043 0.022 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.073 0.206 -9999.0 0.0 -0.652 12.0 12.0 MAP2K1 -0.043 0.119 -9999.0 0.0 -0.402 10.0 10.0 ELK1 0.0 0.035 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.031 0.11 -9999.0 0.0 -0.381 10.0 10.0 mol:GTP -0.003 0.003 -9999.0 0.0 -0.005 62.0 62.0 MAPK1 -0.076 0.209 -9999.0 0.0 -0.638 13.0 13.0 RAF1 -0.035 0.124 -9999.0 0.0 -0.417 10.0 10.0 KRAS 0.03 0.007 -9999.0 0.0 -9999.0 0.0 0.0