Correlation between copy number variations of arm-level result and selected clinical features
Uterine Corpus Endometrioid Carcinoma (Primary solid tumor)
21 August 2015  |  analyses__2015_08_21
Maintainer Information
Citation Information
doi:10.7908/C1D799R6
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2015): Correlation between copy number variations of arm-level result and selected clinical features. Broad Institute of MIT and Harvard. doi:10.7908/C1D799R6
Overview
Introduction

This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and selected clinical features.

Summary

Testing the association between copy number variation 82 arm-level events and 7 clinical features across 536 patients, 232 significant findings detected with Q value < 0.25.

  • 1p gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RESIDUAL_TUMOR', and 'RACE'.

  • 1q gain cnv correlated to 'YEARS_TO_BIRTH' and 'ETHNICITY'.

  • 2p gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'ETHNICITY'.

  • 2q gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 3p gain cnv correlated to 'HISTOLOGICAL_TYPE' and 'RACE'.

  • 3q gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'RADIATION_THERAPY',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 4p gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RESIDUAL_TUMOR', and 'RACE'.

  • 4q gain cnv correlated to 'HISTOLOGICAL_TYPE'.

  • 5p gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 5q gain cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.

  • 6p gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'RADIATION_THERAPY',  'HISTOLOGICAL_TYPE',  'RESIDUAL_TUMOR', and 'RACE'.

  • 6q gain cnv correlated to 'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RESIDUAL_TUMOR', and 'RACE'.

  • 7p gain cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.

  • 7q gain cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.

  • 8p gain cnv correlated to 'Time to Death'.

  • 8q gain cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.

  • 9p gain cnv correlated to 'ETHNICITY'.

  • 9q gain cnv correlated to 'RESIDUAL_TUMOR'.

  • 10p gain cnv correlated to 'YEARS_TO_BIRTH'.

  • 11p gain cnv correlated to 'HISTOLOGICAL_TYPE'.

  • 11q gain cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.

  • 12p gain cnv correlated to 'HISTOLOGICAL_TYPE' and 'RACE'.

  • 12q gain cnv correlated to 'Time to Death',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 13q gain cnv correlated to 'YEARS_TO_BIRTH',  'RADIATION_THERAPY', and 'HISTOLOGICAL_TYPE'.

  • 14q gain cnv correlated to 'HISTOLOGICAL_TYPE'.

  • 15q gain cnv correlated to 'Time to Death' and 'RESIDUAL_TUMOR'.

  • 16p gain cnv correlated to 'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 16q gain cnv correlated to 'RESIDUAL_TUMOR'.

  • 17p gain cnv correlated to 'RESIDUAL_TUMOR'.

  • 17q gain cnv correlated to 'Time to Death',  'HISTOLOGICAL_TYPE',  'RESIDUAL_TUMOR', and 'RACE'.

  • 18p gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RESIDUAL_TUMOR', and 'RACE'.

  • 18q gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.

  • 19p gain cnv correlated to 'YEARS_TO_BIRTH' and 'HISTOLOGICAL_TYPE'.

  • 19q gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 20p gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.

  • 20q gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RESIDUAL_TUMOR', and 'RACE'.

  • 21q gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 22q gain cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.

  • xq gain cnv correlated to 'Time to Death'.

  • 1p loss cnv correlated to 'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.

  • 1q loss cnv correlated to 'Time to Death',  'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.

  • 2p loss cnv correlated to 'RADIATION_THERAPY'.

  • 2q loss cnv correlated to 'Time to Death' and 'RADIATION_THERAPY'.

  • 3p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 3q loss cnv correlated to 'YEARS_TO_BIRTH' and 'HISTOLOGICAL_TYPE'.

  • 4p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 4q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 5p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'ETHNICITY'.

  • 5q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'ETHNICITY'.

  • 6p loss cnv correlated to 'HISTOLOGICAL_TYPE' and 'ETHNICITY'.

  • 6q loss cnv correlated to 'HISTOLOGICAL_TYPE'.

  • 7p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 7q loss cnv correlated to 'YEARS_TO_BIRTH' and 'HISTOLOGICAL_TYPE'.

  • 8p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'RADIATION_THERAPY',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 8q loss cnv correlated to 'HISTOLOGICAL_TYPE'.

  • 9p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.

  • 9q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 10p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 10q loss cnv correlated to 'YEARS_TO_BIRTH' and 'HISTOLOGICAL_TYPE'.

  • 11p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 11q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 12p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.

  • 12q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 13q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 14q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RACE', and 'ETHNICITY'.

  • 15q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 16p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.

  • 16q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE',  'RESIDUAL_TUMOR', and 'RACE'.

  • 17p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RACE'.

  • 17q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'ETHNICITY'.

  • 18p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 18q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.

  • 19p loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.

  • 19q loss cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.

  • 20p loss cnv correlated to 'HISTOLOGICAL_TYPE'.

  • 20q loss cnv correlated to 'RADIATION_THERAPY' and 'HISTOLOGICAL_TYPE'.

  • 21q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • 22q loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH', and 'HISTOLOGICAL_TYPE'.

  • xp loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'ETHNICITY'.

  • xq loss cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'HISTOLOGICAL_TYPE', and 'ETHNICITY'.

Results
Overview of the results

Table 1.  Get Full Table Overview of the association between significant copy number variation of 82 arm-level events and 7 clinical features. Shown in the table are P values (Q values). Thresholded by Q value < 0.25, 232 significant findings detected.

Clinical
Features 		Time
to
Death 		YEARS
TO
BIRTH 		RADIATION
THERAPY 		HISTOLOGICAL
TYPE 		RESIDUAL
TUMOR 		RACE ETHNICITY
nCNV (%) nWild-Type logrank test Wilcoxon-test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test
6p gain 79 (15%) 457 0.0684
(0.188) 		0.0236
(0.0837) 		0.052
(0.153) 		1e-05
(9.9e-05) 		0.0866
(0.223) 		0.0558
(0.161) 		0.706
(0.853)
1p gain 49 (9%) 487 0.000504
(0.00314) 		0.0355
(0.114) 		0.748
(0.878) 		1e-05
(9.9e-05) 		0.064
(0.178) 		0.0307
(0.1) 		1
(1.00)
3q gain 83 (15%) 453 0.0019
(0.00991) 		0.00304
(0.0144) 		0.0112
(0.044) 		1e-05
(9.9e-05) 		0.28
(0.476) 		0.0129
(0.0491) 		1
(1.00)
4p gain 14 (3%) 522 0.0745
(0.198) 		0.0116
(0.0448) 		0.413
(0.605) 		0.00119
(0.0067) 		0.0988
(0.247) 		0.0248
(0.0859) 		0.302
(0.497)
18p gain 72 (13%) 464 0.00737
(0.0316) 		0.000622
(0.0038) 		0.514
(0.691) 		1e-05
(9.9e-05) 		0.0183
(0.0666) 		0.00116
(0.00659) 		0.443
(0.625)
20q gain 131 (24%) 405 1.85e-05
(0.000171) 		4.9e-06
(9.9e-05) 		1
(1.00) 		1e-05
(9.9e-05) 		0.0113
(0.0443) 		0.0163
(0.0604) 		0.759
(0.882)
8p loss 79 (15%) 457 0.0441
(0.135) 		5.39e-05
(0.000435) 		0.0275
(0.093) 		1e-05
(9.9e-05) 		0.469
(0.648) 		0.0571
(0.164) 		0.708
(0.854)
14q loss 60 (11%) 476 0.0017
(0.00912) 		0.00468
(0.021) 		0.768
(0.885) 		1e-05
(9.9e-05) 		0.673
(0.832) 		0.0191
(0.0685) 		0.0625
(0.176)
16q loss 138 (26%) 398 0.00273
(0.0137) 		5.53e-07
(9.9e-05) 		0.916
(0.993) 		1e-05
(9.9e-05) 		0.0162
(0.0604) 		0.0655
(0.182) 		0.769
(0.885)
2p gain 95 (18%) 441 1.49e-05
(0.000142) 		0.00257
(0.0131) 		0.193
(0.386) 		1e-05
(9.9e-05) 		0.515
(0.691) 		0.812
(0.918) 		0.0836
(0.216)
6q gain 64 (12%) 472 0.216
(0.409) 		0.041
(0.128) 		0.257
(0.451) 		1e-05
(9.9e-05) 		0.00997
(0.0409) 		0.01
(0.0409) 		1
(1.00)
17q gain 30 (6%) 506 0.00354
(0.0167) 		0.277
(0.471) 		0.327
(0.526) 		4e-05
(0.000338) 		0.0272
(0.0929) 		0.0117
(0.0449) 		1
(1.00)
18q gain 45 (8%) 491 0.000386
(0.00244) 		0.00745
(0.0317) 		0.748
(0.878) 		1e-05
(9.9e-05) 		0.00684
(0.0302) 		0.263
(0.46) 		0.371
(0.568)
19q gain 56 (10%) 480 0.00151
(0.00826) 		2.45e-07
(7.03e-05) 		1
(1.00) 		1e-05
(9.9e-05) 		0.8
(0.909) 		0.0405
(0.128) 		0.234
(0.424)
20p gain 111 (21%) 425 0.000276
(0.00182) 		6.53e-05
(0.000507) 		0.91
(0.989) 		1e-05
(9.9e-05) 		0.045
(0.136) 		0.133
(0.293) 		0.745
(0.878)
22q gain 31 (6%) 505 0.0297
(0.0981) 		0.00298
(0.0144) 		1
(1.00) 		1e-05
(9.9e-05) 		0.0319
(0.103) 		0.283
(0.478) 		1
(1.00)
5p loss 55 (10%) 481 0.00782
(0.033) 		0.097
(0.244) 		0.237
(0.429) 		1e-05
(9.9e-05) 		0.112
(0.268) 		0.587
(0.749) 		0.0533
(0.155)
5q loss 74 (14%) 462 0.000996
(0.00577) 		0.000806
(0.00479) 		0.194
(0.386) 		1e-05
(9.9e-05) 		0.617
(0.78) 		0.528
(0.699) 		0.0408
(0.128)
9p loss 103 (19%) 433 0.000329
(0.00212) 		1.57e-05
(0.000148) 		0.73
(0.873) 		1e-05
(9.9e-05) 		0.0435
(0.133) 		0.718
(0.862) 		1
(1.00)
12p loss 43 (8%) 493 0.000233
(0.00157) 		0.0593
(0.169) 		0.747
(0.878) 		1e-05
(9.9e-05) 		0.0605
(0.172) 		0.578
(0.739) 		0.342
(0.536)
16p loss 97 (18%) 439 4.34e-05
(0.000361) 		5.45e-05
(0.000435) 		0.905
(0.986) 		1e-05
(9.9e-05) 		0.0109
(0.0431) 		0.245
(0.44) 		0.737
(0.876)
17p loss 129 (24%) 407 9.65e-05
(0.000692) 		3.49e-06
(9.9e-05) 		0.132
(0.293) 		1e-05
(9.9e-05) 		0.124
(0.283) 		0.0126
(0.0482) 		0.539
(0.703)
17q loss 92 (17%) 444 0.003
(0.0144) 		7.09e-05
(0.000535) 		0.396
(0.591) 		1e-05
(9.9e-05) 		0.318
(0.517) 		0.288
(0.483) 		0.0297
(0.0981)
18q loss 64 (12%) 472 0.0481
(0.143) 		0.0226
(0.0807) 		0.305
(0.5) 		1e-05
(9.9e-05) 		0.0795
(0.208) 		0.445
(0.626) 		1
(1.00)
19p loss 59 (11%) 477 0.00022
(0.00152) 		0.0951
(0.241) 		0.88
(0.973) 		1e-05
(9.9e-05) 		0.0914
(0.233) 		0.538
(0.703) 		0.395
(0.591)
xp loss 84 (16%) 452 2.3e-05
(0.000206) 		0.000119
(0.000845) 		0.9
(0.982) 		1e-05
(9.9e-05) 		0.123
(0.283) 		0.164
(0.336) 		0.0786
(0.207)
xq loss 71 (13%) 465 0.00287
(0.0141) 		0.000225
(0.00154) 		0.218
(0.409) 		1e-05
(9.9e-05) 		0.183
(0.368) 		0.14
(0.309) 		0.0471
(0.141)
2q gain 79 (15%) 457 1.07e-05
(0.000104) 		0.0301
(0.0989) 		0.162
(0.336) 		1e-05
(9.9e-05) 		0.258
(0.451) 		0.95
(1.00) 		0.141
(0.309)
5p gain 51 (10%) 485 0.000123
(0.000861) 		0.0251
(0.0863) 		0.753
(0.881) 		1e-05
(9.9e-05) 		0.105
(0.257) 		0.203
(0.398) 		0.655
(0.817)
12q gain 54 (10%) 482 0.0817
(0.212) 		0.677
(0.834) 		0.661
(0.821) 		0.0465
(0.14) 		0.662
(0.821) 		0.0899
(0.23) 		0.388
(0.583)
13q gain 30 (6%) 506 0.401
(0.597) 		0.0147
(0.0554) 		0.0351
(0.113) 		1e-05
(9.9e-05) 		0.323
(0.522) 		0.54
(0.703) 		1
(1.00)
16p gain 27 (5%) 509 0.258
(0.451) 		0.0169
(0.062) 		0.537
(0.703) 		0.0421
(0.131) 		0.182
(0.367) 		0.0746
(0.198) 		0.556
(0.717)
21q gain 38 (7%) 498 0.0245
(0.0857) 		0.00089
(0.00521) 		0.284
(0.478) 		1e-05
(9.9e-05) 		0.346
(0.54) 		0.216
(0.409) 		1
(1.00)
1p loss 25 (5%) 511 0.412
(0.605) 		0.0365
(0.116) 		0.674
(0.832) 		1e-05
(9.9e-05) 		0.00197
(0.0102) 		0.688
(0.843) 		1
(1.00)
1q loss 14 (3%) 522 0.0804
(0.21) 		0.296
(0.493) 		0.598
(0.758) 		4e-05
(0.000338) 		0.0185
(0.0667) 		0.428
(0.614) 		1
(1.00)
3p loss 51 (10%) 485 0.0073
(0.0315) 		0.00712
(0.0312) 		0.758
(0.882) 		1e-05
(9.9e-05) 		0.942
(1.00) 		0.637
(0.796) 		0.38
(0.578)
4p loss 104 (19%) 432 0.00135
(0.00744) 		3.76e-05
(0.000332) 		0.564
(0.724) 		1e-05
(9.9e-05) 		0.405
(0.601) 		0.293
(0.489) 		0.201
(0.397)
4q loss 104 (19%) 432 9.24e-05
(0.000671) 		4.91e-05
(0.000403) 		1
(1.00) 		1e-05
(9.9e-05) 		0.576
(0.738) 		0.228
(0.417) 		1
(1.00)
7p loss 44 (8%) 492 0.0104
(0.0421) 		7.29e-05
(0.000544) 		0.62
(0.783) 		1e-05
(9.9e-05) 		0.171
(0.349) 		0.153
(0.323) 		0.312
(0.508)
9q loss 122 (23%) 414 0.000372
(0.00237) 		7.35e-09
(4.22e-06) 		0.332
(0.527) 		1e-05
(9.9e-05) 		0.217
(0.409) 		0.229
(0.418) 		1
(1.00)
10p loss 43 (8%) 493 0.0248
(0.0859) 		0.0176
(0.0642) 		1
(1.00) 		1e-05
(9.9e-05) 		0.201
(0.397) 		0.11
(0.266) 		0.627
(0.788)
11p loss 74 (14%) 462 0.000257
(0.00172) 		0.000809
(0.00479) 		0.893
(0.976) 		1e-05
(9.9e-05) 		0.356
(0.553) 		0.113
(0.269) 		1
(1.00)
11q loss 72 (13%) 464 0.000787
(0.00476) 		0.00276
(0.0137) 		0.59
(0.751) 		1e-05
(9.9e-05) 		0.154
(0.325) 		0.107
(0.258) 		0.45
(0.629)
12q loss 36 (7%) 500 0.00134
(0.00744) 		0.0715
(0.194) 		1
(1.00) 		1e-05
(9.9e-05) 		0.68
(0.836) 		0.508
(0.685) 		0.252
(0.448)
13q loss 92 (17%) 444 0.00226
(0.0116) 		0.0106
(0.0422) 		0.397
(0.591) 		1e-05
(9.9e-05) 		0.453
(0.63) 		0.741
(0.876) 		0.492
(0.669)
15q loss 108 (20%) 428 0.00275
(0.0137) 		8.93e-07
(9.9e-05) 		0.732
(0.874) 		1e-05
(9.9e-05) 		0.324
(0.523) 		0.243
(0.437) 		1
(1.00)
18p loss 51 (10%) 485 0.0629
(0.176) 		0.0242
(0.0851) 		0.425
(0.613) 		7e-05
(0.000535) 		0.106
(0.258) 		0.893
(0.976) 		1
(1.00)
21q loss 54 (10%) 482 0.0522
(0.153) 		0.00453
(0.0206) 		0.764
(0.885) 		1e-05
(9.9e-05) 		0.269
(0.466) 		0.386
(0.582) 		1
(1.00)
22q loss 108 (20%) 428 0.00443
(0.0204) 		3.94e-05
(0.000338) 		0.817
(0.919) 		1e-05
(9.9e-05) 		0.225
(0.416) 		0.163
(0.336) 		0.331
(0.526)
1q gain 187 (35%) 349 0.221
(0.411) 		0.00867
(0.0358) 		0.925
(1) 		0.492
(0.669) 		1
(1.00) 		0.471
(0.648) 		0.0967
(0.244)
3p gain 48 (9%) 488 0.254
(0.448) 		0.275
(0.47) 		0.627
(0.788) 		0.00051
(0.00315) 		0.372
(0.568) 		0.0289
(0.0964) 		1
(1.00)
5q gain 20 (4%) 516 0.101
(0.249) 		0.561
(0.722) 		1
(1.00) 		0.00032
(0.00209) 		0.266
(0.461) 		0.527
(0.698) 		1
(1.00)
7p gain 67 (12%) 469 0.0536
(0.155) 		0.301
(0.497) 		0.784
(0.898) 		0.0432
(0.133) 		0.517
(0.692) 		0.851
(0.95) 		0.704
(0.853)
7q gain 66 (12%) 470 0.00102
(0.00583) 		0.265
(0.461) 		0.78
(0.895) 		0.072
(0.194) 		0.54
(0.703) 		0.873
(0.973) 		0.704
(0.853)
8q gain 158 (29%) 378 0.00444
(0.0204) 		0.795
(0.907) 		0.488
(0.667) 		0.00372
(0.0174) 		0.221
(0.411) 		0.738
(0.876) 		0.164
(0.336)
11q gain 19 (4%) 517 0.00457
(0.0206) 		0.361
(0.557) 		0.228
(0.417) 		0.0288
(0.0964) 		0.128
(0.288) 		0.549
(0.712) 		1
(1.00)
12p gain 71 (13%) 465 0.291
(0.487) 		0.429
(0.614) 		0.79
(0.903) 		2e-05
(0.000182) 		0.704
(0.853) 		0.0679
(0.187) 		0.141
(0.309)
15q gain 11 (2%) 525 0.0106
(0.0422) 		0.553
(0.715) 		0.124
(0.283) 		0.82
(0.921) 		0.0397
(0.126) 		0.433
(0.617) 		0.302
(0.497)
19p gain 53 (10%) 483 0.155
(0.325) 		2.55e-06
(9.9e-05) 		0.88
(0.973) 		1e-05
(9.9e-05) 		0.811
(0.918) 		0.272
(0.469) 		1
(1.00)
2q loss 17 (3%) 519 0.00609
(0.0271) 		0.103
(0.252) 		0.0695
(0.189) 		0.339
(0.533) 		0.424
(0.613) 		0.525
(0.698) 		0.453
(0.63)
3q loss 31 (6%) 505 0.428
(0.614) 		0.0691
(0.189) 		0.438
(0.621) 		8e-05
(0.000589) 		0.47
(0.648) 		0.128
(0.289) 		1
(1.00)
6p loss 18 (3%) 518 0.754
(0.881) 		0.102
(0.251) 		0.598
(0.758) 		1e-05
(9.9e-05) 		0.497
(0.675) 		0.769
(0.885) 		0.0975
(0.244)
7q loss 42 (8%) 494 0.215
(0.409) 		0.00176
(0.00928) 		0.739
(0.876) 		1e-05
(9.9e-05) 		0.412
(0.605) 		0.422
(0.613) 		0.357
(0.553)
10q loss 40 (7%) 496 0.132
(0.293) 		0.00847
(0.0352) 		0.726
(0.87) 		1e-05
(9.9e-05) 		0.891
(0.976) 		0.226
(0.417) 		1
(1.00)
19q loss 56 (10%) 480 0.00175
(0.00928) 		0.123
(0.283) 		0.878
(0.973) 		1e-05
(9.9e-05) 		0.163
(0.336) 		0.365
(0.561) 		0.194
(0.386)
20q loss 9 (2%) 527 0.179
(0.362) 		0.715
(0.86) 		0.0448
(0.136) 		0.00717
(0.0312) 		1
(1.00) 		0.509
(0.686) 		0.302
(0.497)
4q gain 8 (1%) 528 0.759
(0.882) 		0.456
(0.632) 		1
(1.00) 		0.0275
(0.093) 		0.48
(0.657) 		0.334
(0.528) 		0.147
(0.316)
8p gain 118 (22%) 418 0.0758
(0.201) 		0.147
(0.316) 		0.124
(0.283) 		0.805
(0.913) 		0.16
(0.335) 		0.421
(0.613) 		0.536
(0.703)
9p gain 21 (4%) 515 0.281
(0.476) 		0.89
(0.976) 		0.228
(0.417) 		0.121
(0.281) 		0.252
(0.448) 		0.43
(0.614) 		0.0162
(0.0604)
9q gain 8 (1%) 528 0.329
(0.526) 		0.69
(0.845) 		0.24
(0.434) 		0.253
(0.448) 		0.0747
(0.198) 		0.116
(0.276) 		0.212
(0.409)
10p gain 116 (22%) 420 0.814
(0.918) 		0.0619
(0.175) 		0.52
(0.694) 		0.693
(0.846) 		0.765
(0.885) 		0.215
(0.409) 		0.207
(0.404)
11p gain 23 (4%) 513 0.13
(0.292) 		0.153
(0.323) 		0.83
(0.931) 		6e-05
(0.000472) 		0.147
(0.316) 		0.425
(0.613) 		0.476
(0.653)
14q gain 37 (7%) 499 0.357
(0.553) 		0.439
(0.621) 		1
(1.00) 		1e-05
(9.9e-05) 		0.383
(0.58) 		0.363
(0.559) 		1
(1.00)
16q gain 10 (2%) 526 0.85
(0.95) 		0.211
(0.409) 		0.525
(0.698) 		0.12
(0.28) 		0.00159
(0.00861) 		0.118
(0.278) 		0.273
(0.47)
17p gain 12 (2%) 524 0.119
(0.28) 		0.507
(0.685) 		0.544
(0.706) 		0.213
(0.409) 		0.0998
(0.248) 		1
(1.00) 		0.33
(0.526)
xq gain 64 (12%) 472 0.00793
(0.0332) 		0.211
(0.409) 		0.126
(0.287) 		0.344
(0.537) 		0.112
(0.269) 		1
(1.00) 		1
(1.00)
2p loss 11 (2%) 525 0.131
(0.292) 		0.192
(0.386) 		0.0485
(0.143) 		0.451
(0.629) 		0.152
(0.323) 		0.423
(0.613) 		0.33
(0.526)
6q loss 25 (5%) 511 0.631
(0.791) 		0.215
(0.409) 		1
(1.00) 		1e-05
(9.9e-05) 		0.381
(0.578) 		1
(1.00) 		0.164
(0.336)
8q loss 25 (5%) 511 0.882
(0.974) 		0.221
(0.411) 		0.661
(0.821) 		1e-05
(9.9e-05) 		0.408
(0.604) 		0.311
(0.508) 		0.537
(0.703)
20p loss 19 (4%) 517 0.875
(0.973) 		0.207
(0.404) 		0.148
(0.318) 		0.00291
(0.0142) 		0.144
(0.312) 		0.439
(0.621) 		0.123
(0.283)
10q gain 109 (20%) 427 0.448
(0.629) 		0.41
(0.605) 		0.321
(0.521) 		0.797
(0.908) 		0.336
(0.53) 		0.174
(0.355) 		1
(1.00)
xp gain 64 (12%) 472 0.274
(0.47) 		0.247
(0.442) 		0.89
(0.976) 		0.385
(0.582) 		0.215
(0.409) 		0.916
(0.993) 		0.704
(0.853)
'1p gain' versus 'Time to Death'

P value = 0.000504 (logrank test), Q value = 0.0031

Table S1.  Gene #1: '1p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
1P GAIN MUTATED 49 13 0.1 - 92.9 (20.5)
1P GAIN WILD-TYPE 485 68 0.0 - 225.5 (28.1)

Figure S1.  Get High-res Image Gene #1: '1p gain' versus Clinical Feature #1: 'Time to Death'

'1p gain' versus 'YEARS_TO_BIRTH'

P value = 0.0355 (Wilcoxon-test), Q value = 0.11

Table S2.  Gene #1: '1p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
1P GAIN MUTATED 49 67.1 (9.4)
1P GAIN WILD-TYPE 485 63.7 (11.3)

Figure S2.  Get High-res Image Gene #1: '1p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'1p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S3.  Gene #1: '1p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
1P GAIN MUTATED 21 2 26
1P GAIN WILD-TYPE 380 20 87

Figure S3.  Get High-res Image Gene #1: '1p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'1p gain' versus 'RESIDUAL_TUMOR'

P value = 0.064 (Fisher's exact test), Q value = 0.18

Table S4.  Gene #1: '1p gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
1P GAIN MUTATED 31 0 2 7
1P GAIN WILD-TYPE 339 22 15 30

Figure S4.  Get High-res Image Gene #1: '1p gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'1p gain' versus 'RACE'

P value = 0.0307 (Fisher's exact test), Q value = 0.1

Table S5.  Gene #1: '1p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
1P GAIN MUTATED 0 1 17 2 26
1P GAIN WILD-TYPE 4 19 89 7 342

Figure S5.  Get High-res Image Gene #1: '1p gain' versus Clinical Feature #6: 'RACE'

'1q gain' versus 'YEARS_TO_BIRTH'

P value = 0.00867 (Wilcoxon-test), Q value = 0.036

Table S6.  Gene #2: '1q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
1Q GAIN MUTATED 187 65.9 (10.3)
1Q GAIN WILD-TYPE 347 63.0 (11.5)

Figure S6.  Get High-res Image Gene #2: '1q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'1q gain' versus 'ETHNICITY'

P value = 0.0967 (Fisher's exact test), Q value = 0.24

Table S7.  Gene #2: '1q gain' versus Clinical Feature #7: 'ETHNICITY'

nPatients HISPANIC OR LATINO NOT HISPANIC OR LATINO
ALL 15 372
1Q GAIN MUTATED 2 138
1Q GAIN WILD-TYPE 13 234

Figure S7.  Get High-res Image Gene #2: '1q gain' versus Clinical Feature #7: 'ETHNICITY'

'2p gain' versus 'Time to Death'

P value = 1.49e-05 (logrank test), Q value = 0.00014

Table S8.  Gene #3: '2p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
2P GAIN MUTATED 94 27 0.1 - 149.6 (22.9)
2P GAIN WILD-TYPE 440 54 0.0 - 225.5 (28.0)

Figure S8.  Get High-res Image Gene #3: '2p gain' versus Clinical Feature #1: 'Time to Death'

'2p gain' versus 'YEARS_TO_BIRTH'

P value = 0.00257 (Wilcoxon-test), Q value = 0.013

Table S9.  Gene #3: '2p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
2P GAIN MUTATED 94 67.1 (10.4)
2P GAIN WILD-TYPE 440 63.3 (11.3)

Figure S9.  Get High-res Image Gene #3: '2p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'2p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S10.  Gene #3: '2p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
2P GAIN MUTATED 43 5 47
2P GAIN WILD-TYPE 358 17 66

Figure S10.  Get High-res Image Gene #3: '2p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'2p gain' versus 'ETHNICITY'

P value = 0.0836 (Fisher's exact test), Q value = 0.22

Table S11.  Gene #3: '2p gain' versus Clinical Feature #7: 'ETHNICITY'

nPatients HISPANIC OR LATINO NOT HISPANIC OR LATINO
ALL 15 372
2P GAIN MUTATED 0 69
2P GAIN WILD-TYPE 15 303

Figure S11.  Get High-res Image Gene #3: '2p gain' versus Clinical Feature #7: 'ETHNICITY'

'2q gain' versus 'Time to Death'

P value = 1.07e-05 (logrank test), Q value = 1e-04

Table S12.  Gene #4: '2q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
2Q GAIN MUTATED 78 23 0.1 - 110.1 (22.3)
2Q GAIN WILD-TYPE 456 58 0.0 - 225.5 (28.2)

Figure S12.  Get High-res Image Gene #4: '2q gain' versus Clinical Feature #1: 'Time to Death'

'2q gain' versus 'YEARS_TO_BIRTH'

P value = 0.0301 (Wilcoxon-test), Q value = 0.099

Table S13.  Gene #4: '2q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
2Q GAIN MUTATED 78 66.4 (10.3)
2Q GAIN WILD-TYPE 456 63.6 (11.3)

Figure S13.  Get High-res Image Gene #4: '2q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'2q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S14.  Gene #4: '2q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
2Q GAIN MUTATED 37 4 38
2Q GAIN WILD-TYPE 364 18 75

Figure S14.  Get High-res Image Gene #4: '2q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'3p gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.00051 (Fisher's exact test), Q value = 0.0031

Table S15.  Gene #5: '3p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
3P GAIN MUTATED 27 0 21
3P GAIN WILD-TYPE 374 22 92

Figure S15.  Get High-res Image Gene #5: '3p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'3p gain' versus 'RACE'

P value = 0.0289 (Fisher's exact test), Q value = 0.096

Table S16.  Gene #5: '3p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
3P GAIN MUTATED 0 0 14 3 28
3P GAIN WILD-TYPE 4 20 92 6 340

Figure S16.  Get High-res Image Gene #5: '3p gain' versus Clinical Feature #6: 'RACE'

'3q gain' versus 'Time to Death'

P value = 0.0019 (logrank test), Q value = 0.0099

Table S17.  Gene #6: '3q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
3Q GAIN MUTATED 83 22 0.1 - 225.5 (22.6)
3Q GAIN WILD-TYPE 451 59 0.0 - 185.8 (27.9)

Figure S17.  Get High-res Image Gene #6: '3q gain' versus Clinical Feature #1: 'Time to Death'

'3q gain' versus 'YEARS_TO_BIRTH'

P value = 0.00304 (Wilcoxon-test), Q value = 0.014

Table S18.  Gene #6: '3q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
3Q GAIN MUTATED 83 67.2 (9.7)
3Q GAIN WILD-TYPE 451 63.4 (11.4)

Figure S18.  Get High-res Image Gene #6: '3q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'3q gain' versus 'RADIATION_THERAPY'

P value = 0.0112 (Fisher's exact test), Q value = 0.044

Table S19.  Gene #6: '3q gain' versus Clinical Feature #3: 'RADIATION_THERAPY'

nPatients NO YES
ALL 284 218
3Q GAIN MUTATED 32 43
3Q GAIN WILD-TYPE 252 175

Figure S19.  Get High-res Image Gene #6: '3q gain' versus Clinical Feature #3: 'RADIATION_THERAPY'

'3q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S20.  Gene #6: '3q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
3Q GAIN MUTATED 36 4 43
3Q GAIN WILD-TYPE 365 18 70

Figure S20.  Get High-res Image Gene #6: '3q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'3q gain' versus 'RACE'

P value = 0.0129 (Fisher's exact test), Q value = 0.049

Table S21.  Gene #6: '3q gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
3Q GAIN MUTATED 0 3 26 3 45
3Q GAIN WILD-TYPE 4 17 80 6 323

Figure S21.  Get High-res Image Gene #6: '3q gain' versus Clinical Feature #6: 'RACE'

'4p gain' versus 'Time to Death'

P value = 0.0745 (logrank test), Q value = 0.2

Table S22.  Gene #7: '4p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
4P GAIN MUTATED 14 4 5.9 - 97.7 (20.4)
4P GAIN WILD-TYPE 520 77 0.0 - 225.5 (27.5)

Figure S22.  Get High-res Image Gene #7: '4p gain' versus Clinical Feature #1: 'Time to Death'

'4p gain' versus 'YEARS_TO_BIRTH'

P value = 0.0116 (Wilcoxon-test), Q value = 0.045

Table S23.  Gene #7: '4p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
4P GAIN MUTATED 14 70.3 (10.4)
4P GAIN WILD-TYPE 520 63.8 (11.2)

Figure S23.  Get High-res Image Gene #7: '4p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'4p gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.00119 (Fisher's exact test), Q value = 0.0067

Table S24.  Gene #7: '4p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
4P GAIN MUTATED 5 0 9
4P GAIN WILD-TYPE 396 22 104

Figure S24.  Get High-res Image Gene #7: '4p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'4p gain' versus 'RESIDUAL_TUMOR'

P value = 0.0988 (Fisher's exact test), Q value = 0.25

Table S25.  Gene #7: '4p gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
4P GAIN MUTATED 10 1 2 0
4P GAIN WILD-TYPE 360 21 15 37

Figure S25.  Get High-res Image Gene #7: '4p gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'4p gain' versus 'RACE'

P value = 0.0248 (Fisher's exact test), Q value = 0.086

Table S26.  Gene #7: '4p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
4P GAIN MUTATED 0 2 6 0 5
4P GAIN WILD-TYPE 4 18 100 9 363

Figure S26.  Get High-res Image Gene #7: '4p gain' versus Clinical Feature #6: 'RACE'

'4q gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.0275 (Fisher's exact test), Q value = 0.093

Table S27.  Gene #8: '4q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
4Q GAIN MUTATED 3 0 5
4Q GAIN WILD-TYPE 398 22 108

Figure S27.  Get High-res Image Gene #8: '4q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'5p gain' versus 'Time to Death'

P value = 0.000123 (logrank test), Q value = 0.00086

Table S28.  Gene #9: '5p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
5P GAIN MUTATED 51 15 0.4 - 110.1 (22.0)
5P GAIN WILD-TYPE 483 66 0.0 - 225.5 (27.9)

Figure S28.  Get High-res Image Gene #9: '5p gain' versus Clinical Feature #1: 'Time to Death'

'5p gain' versus 'YEARS_TO_BIRTH'

P value = 0.0251 (Wilcoxon-test), Q value = 0.086

Table S29.  Gene #9: '5p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
5P GAIN MUTATED 51 67.1 (9.8)
5P GAIN WILD-TYPE 483 63.7 (11.3)

Figure S29.  Get High-res Image Gene #9: '5p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'5p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S30.  Gene #9: '5p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
5P GAIN MUTATED 16 3 32
5P GAIN WILD-TYPE 385 19 81

Figure S30.  Get High-res Image Gene #9: '5p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'5q gain' versus 'Time to Death'

P value = 0.101 (logrank test), Q value = 0.25

Table S31.  Gene #10: '5q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
5Q GAIN MUTATED 20 5 1.4 - 79.1 (25.7)
5Q GAIN WILD-TYPE 514 76 0.0 - 225.5 (27.4)

Figure S31.  Get High-res Image Gene #10: '5q gain' versus Clinical Feature #1: 'Time to Death'

'5q gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.00032 (Fisher's exact test), Q value = 0.0021

Table S32.  Gene #10: '5q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
5Q GAIN MUTATED 8 0 12
5Q GAIN WILD-TYPE 393 22 101

Figure S32.  Get High-res Image Gene #10: '5q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'6p gain' versus 'Time to Death'

P value = 0.0684 (logrank test), Q value = 0.19

Table S33.  Gene #11: '6p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
6P GAIN MUTATED 79 18 0.1 - 110.1 (31.1)
6P GAIN WILD-TYPE 455 63 0.0 - 225.5 (27.2)

Figure S33.  Get High-res Image Gene #11: '6p gain' versus Clinical Feature #1: 'Time to Death'

'6p gain' versus 'YEARS_TO_BIRTH'

P value = 0.0236 (Wilcoxon-test), Q value = 0.084

Table S34.  Gene #11: '6p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
6P GAIN MUTATED 79 66.2 (9.7)
6P GAIN WILD-TYPE 455 63.6 (11.4)

Figure S34.  Get High-res Image Gene #11: '6p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'6p gain' versus 'RADIATION_THERAPY'

P value = 0.052 (Fisher's exact test), Q value = 0.15

Table S35.  Gene #11: '6p gain' versus Clinical Feature #3: 'RADIATION_THERAPY'

nPatients NO YES
ALL 284 218
6P GAIN MUTATED 32 38
6P GAIN WILD-TYPE 252 180

Figure S35.  Get High-res Image Gene #11: '6p gain' versus Clinical Feature #3: 'RADIATION_THERAPY'

'6p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S36.  Gene #11: '6p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
6P GAIN MUTATED 38 1 40
6P GAIN WILD-TYPE 363 21 73

Figure S36.  Get High-res Image Gene #11: '6p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'6p gain' versus 'RESIDUAL_TUMOR'

P value = 0.0866 (Fisher's exact test), Q value = 0.22

Table S37.  Gene #11: '6p gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
6P GAIN MUTATED 46 2 3 10
6P GAIN WILD-TYPE 324 20 14 27

Figure S37.  Get High-res Image Gene #11: '6p gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'6p gain' versus 'RACE'

P value = 0.0558 (Fisher's exact test), Q value = 0.16

Table S38.  Gene #11: '6p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
6P GAIN MUTATED 0 2 25 2 46
6P GAIN WILD-TYPE 4 18 81 7 322

Figure S38.  Get High-res Image Gene #11: '6p gain' versus Clinical Feature #6: 'RACE'

'6q gain' versus 'YEARS_TO_BIRTH'

P value = 0.041 (Wilcoxon-test), Q value = 0.13

Table S39.  Gene #12: '6q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
6Q GAIN MUTATED 64 66.3 (10.3)
6Q GAIN WILD-TYPE 470 63.7 (11.3)

Figure S39.  Get High-res Image Gene #12: '6q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'6q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S40.  Gene #12: '6q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
6Q GAIN MUTATED 34 1 29
6Q GAIN WILD-TYPE 367 21 84

Figure S40.  Get High-res Image Gene #12: '6q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'6q gain' versus 'RESIDUAL_TUMOR'

P value = 0.00997 (Fisher's exact test), Q value = 0.041

Table S41.  Gene #12: '6q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
6Q GAIN MUTATED 35 1 3 10
6Q GAIN WILD-TYPE 335 21 14 27

Figure S41.  Get High-res Image Gene #12: '6q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'6q gain' versus 'RACE'

P value = 0.01 (Fisher's exact test), Q value = 0.041

Table S42.  Gene #12: '6q gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
6Q GAIN MUTATED 0 1 23 2 35
6Q GAIN WILD-TYPE 4 19 83 7 333

Figure S42.  Get High-res Image Gene #12: '6q gain' versus Clinical Feature #6: 'RACE'

'7p gain' versus 'Time to Death'

P value = 0.0536 (logrank test), Q value = 0.16

Table S43.  Gene #13: '7p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
7P GAIN MUTATED 66 14 0.1 - 125.4 (21.4)
7P GAIN WILD-TYPE 468 67 0.0 - 225.5 (28.3)

Figure S43.  Get High-res Image Gene #13: '7p gain' versus Clinical Feature #1: 'Time to Death'

'7p gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.0432 (Fisher's exact test), Q value = 0.13

Table S44.  Gene #13: '7p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
7P GAIN MUTATED 42 4 21
7P GAIN WILD-TYPE 359 18 92

Figure S44.  Get High-res Image Gene #13: '7p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'7q gain' versus 'Time to Death'

P value = 0.00102 (logrank test), Q value = 0.0058

Table S45.  Gene #14: '7q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
7Q GAIN MUTATED 65 17 0.1 - 125.4 (20.5)
7Q GAIN WILD-TYPE 469 64 0.0 - 225.5 (28.3)

Figure S45.  Get High-res Image Gene #14: '7q gain' versus Clinical Feature #1: 'Time to Death'

'7q gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.072 (Fisher's exact test), Q value = 0.19

Table S46.  Gene #14: '7q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
7Q GAIN MUTATED 42 4 20
7Q GAIN WILD-TYPE 359 18 93

Figure S46.  Get High-res Image Gene #14: '7q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'8p gain' versus 'Time to Death'

P value = 0.0758 (logrank test), Q value = 0.2

Table S47.  Gene #15: '8p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
8P GAIN MUTATED 117 24 0.1 - 225.5 (25.5)
8P GAIN WILD-TYPE 417 57 0.0 - 185.8 (27.4)

Figure S47.  Get High-res Image Gene #15: '8p gain' versus Clinical Feature #1: 'Time to Death'

'8q gain' versus 'Time to Death'

P value = 0.00444 (logrank test), Q value = 0.02

Table S48.  Gene #16: '8q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
8Q GAIN MUTATED 156 35 0.1 - 225.5 (27.1)
8Q GAIN WILD-TYPE 378 46 0.0 - 185.8 (27.4)

Figure S48.  Get High-res Image Gene #16: '8q gain' versus Clinical Feature #1: 'Time to Death'

'8q gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.00372 (Fisher's exact test), Q value = 0.017

Table S49.  Gene #16: '8q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
8Q GAIN MUTATED 103 8 47
8Q GAIN WILD-TYPE 298 14 66

Figure S49.  Get High-res Image Gene #16: '8q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'9p gain' versus 'ETHNICITY'

P value = 0.0162 (Fisher's exact test), Q value = 0.06

Table S50.  Gene #17: '9p gain' versus Clinical Feature #7: 'ETHNICITY'

nPatients HISPANIC OR LATINO NOT HISPANIC OR LATINO
ALL 15 372
9P GAIN MUTATED 3 12
9P GAIN WILD-TYPE 12 360

Figure S50.  Get High-res Image Gene #17: '9p gain' versus Clinical Feature #7: 'ETHNICITY'

'9q gain' versus 'RESIDUAL_TUMOR'

P value = 0.0747 (Fisher's exact test), Q value = 0.2

Table S51.  Gene #18: '9q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
9Q GAIN MUTATED 3 1 0 2
9Q GAIN WILD-TYPE 367 21 17 35

Figure S51.  Get High-res Image Gene #18: '9q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'10p gain' versus 'YEARS_TO_BIRTH'

P value = 0.0619 (Wilcoxon-test), Q value = 0.17

Table S52.  Gene #19: '10p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
10P GAIN MUTATED 116 65.5 (12.0)
10P GAIN WILD-TYPE 418 63.6 (10.9)

Figure S52.  Get High-res Image Gene #19: '10p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'11p gain' versus 'HISTOLOGICAL_TYPE'

P value = 6e-05 (Fisher's exact test), Q value = 0.00047

Table S53.  Gene #21: '11p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
11P GAIN MUTATED 8 0 15
11P GAIN WILD-TYPE 393 22 98

Figure S53.  Get High-res Image Gene #21: '11p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'11q gain' versus 'Time to Death'

P value = 0.00457 (logrank test), Q value = 0.021

Table S54.  Gene #22: '11q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
11Q GAIN MUTATED 19 7 2.1 - 92.9 (25.5)
11Q GAIN WILD-TYPE 515 74 0.0 - 225.5 (27.4)

Figure S54.  Get High-res Image Gene #22: '11q gain' versus Clinical Feature #1: 'Time to Death'

'11q gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.0288 (Fisher's exact test), Q value = 0.096

Table S55.  Gene #22: '11q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
11Q GAIN MUTATED 10 0 9
11Q GAIN WILD-TYPE 391 22 104

Figure S55.  Get High-res Image Gene #22: '11q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'12p gain' versus 'HISTOLOGICAL_TYPE'

P value = 2e-05 (Fisher's exact test), Q value = 0.00018

Table S56.  Gene #23: '12p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
12P GAIN MUTATED 37 3 31
12P GAIN WILD-TYPE 364 19 82

Figure S56.  Get High-res Image Gene #23: '12p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'12p gain' versus 'RACE'

P value = 0.0679 (Fisher's exact test), Q value = 0.19

Table S57.  Gene #23: '12p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
12P GAIN MUTATED 0 6 18 2 42
12P GAIN WILD-TYPE 4 14 88 7 326

Figure S57.  Get High-res Image Gene #23: '12p gain' versus Clinical Feature #6: 'RACE'

'12q gain' versus 'Time to Death'

P value = 0.0817 (logrank test), Q value = 0.21

Table S58.  Gene #24: '12q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
12Q GAIN MUTATED 54 4 2.1 - 149.6 (30.7)
12Q GAIN WILD-TYPE 480 77 0.0 - 225.5 (27.2)

Figure S58.  Get High-res Image Gene #24: '12q gain' versus Clinical Feature #1: 'Time to Death'

'12q gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.0465 (Fisher's exact test), Q value = 0.14

Table S59.  Gene #24: '12q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
12Q GAIN MUTATED 33 3 18
12Q GAIN WILD-TYPE 368 19 95

Figure S59.  Get High-res Image Gene #24: '12q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'12q gain' versus 'RACE'

P value = 0.0899 (Fisher's exact test), Q value = 0.23

Table S60.  Gene #24: '12q gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
12Q GAIN MUTATED 0 5 12 2 32
12Q GAIN WILD-TYPE 4 15 94 7 336

Figure S60.  Get High-res Image Gene #24: '12q gain' versus Clinical Feature #6: 'RACE'

'13q gain' versus 'YEARS_TO_BIRTH'

P value = 0.0147 (Wilcoxon-test), Q value = 0.055

Table S61.  Gene #25: '13q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
13Q GAIN MUTATED 30 68.3 (6.5)
13Q GAIN WILD-TYPE 504 63.7 (11.4)

Figure S61.  Get High-res Image Gene #25: '13q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'13q gain' versus 'RADIATION_THERAPY'

P value = 0.0351 (Fisher's exact test), Q value = 0.11

Table S62.  Gene #25: '13q gain' versus Clinical Feature #3: 'RADIATION_THERAPY'

nPatients NO YES
ALL 284 218
13Q GAIN MUTATED 11 19
13Q GAIN WILD-TYPE 273 199

Figure S62.  Get High-res Image Gene #25: '13q gain' versus Clinical Feature #3: 'RADIATION_THERAPY'

'13q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S63.  Gene #25: '13q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
13Q GAIN MUTATED 8 1 21
13Q GAIN WILD-TYPE 393 21 92

Figure S63.  Get High-res Image Gene #25: '13q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'14q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S64.  Gene #26: '14q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
14Q GAIN MUTATED 15 2 20
14Q GAIN WILD-TYPE 386 20 93

Figure S64.  Get High-res Image Gene #26: '14q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'15q gain' versus 'Time to Death'

P value = 0.0106 (logrank test), Q value = 0.042

Table S65.  Gene #27: '15q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
15Q GAIN MUTATED 11 4 4.4 - 75.7 (20.8)
15Q GAIN WILD-TYPE 523 77 0.0 - 225.5 (27.6)

Figure S65.  Get High-res Image Gene #27: '15q gain' versus Clinical Feature #1: 'Time to Death'

'15q gain' versus 'RESIDUAL_TUMOR'

P value = 0.0397 (Fisher's exact test), Q value = 0.13

Table S66.  Gene #27: '15q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
15Q GAIN MUTATED 4 1 1 2
15Q GAIN WILD-TYPE 366 21 16 35

Figure S66.  Get High-res Image Gene #27: '15q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'16p gain' versus 'YEARS_TO_BIRTH'

P value = 0.0169 (Wilcoxon-test), Q value = 0.062

Table S67.  Gene #28: '16p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
16P GAIN MUTATED 27 68.4 (8.8)
16P GAIN WILD-TYPE 507 63.8 (11.3)

Figure S67.  Get High-res Image Gene #28: '16p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'16p gain' versus 'HISTOLOGICAL_TYPE'

P value = 0.0421 (Fisher's exact test), Q value = 0.13

Table S68.  Gene #28: '16p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
16P GAIN MUTATED 15 1 11
16P GAIN WILD-TYPE 386 21 102

Figure S68.  Get High-res Image Gene #28: '16p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'16p gain' versus 'RACE'

P value = 0.0746 (Fisher's exact test), Q value = 0.2

Table S69.  Gene #28: '16p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
16P GAIN MUTATED 0 0 10 1 13
16P GAIN WILD-TYPE 4 20 96 8 355

Figure S69.  Get High-res Image Gene #28: '16p gain' versus Clinical Feature #6: 'RACE'

'16q gain' versus 'RESIDUAL_TUMOR'

P value = 0.00159 (Fisher's exact test), Q value = 0.0086

Table S70.  Gene #29: '16q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
16Q GAIN MUTATED 3 3 0 2
16Q GAIN WILD-TYPE 367 19 17 35

Figure S70.  Get High-res Image Gene #29: '16q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'17p gain' versus 'RESIDUAL_TUMOR'

P value = 0.0998 (Fisher's exact test), Q value = 0.25

Table S71.  Gene #30: '17p gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
17P GAIN MUTATED 7 1 0 3
17P GAIN WILD-TYPE 363 21 17 34

Figure S71.  Get High-res Image Gene #30: '17p gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'17q gain' versus 'Time to Death'

P value = 0.00354 (logrank test), Q value = 0.017

Table S72.  Gene #31: '17q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
17Q GAIN MUTATED 30 8 0.1 - 78.4 (19.3)
17Q GAIN WILD-TYPE 504 73 0.0 - 225.5 (28.4)

Figure S72.  Get High-res Image Gene #31: '17q gain' versus Clinical Feature #1: 'Time to Death'

'17q gain' versus 'HISTOLOGICAL_TYPE'

P value = 4e-05 (Fisher's exact test), Q value = 0.00034

Table S73.  Gene #31: '17q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
17Q GAIN MUTATED 13 0 17
17Q GAIN WILD-TYPE 388 22 96

Figure S73.  Get High-res Image Gene #31: '17q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'17q gain' versus 'RESIDUAL_TUMOR'

P value = 0.0272 (Fisher's exact test), Q value = 0.093

Table S74.  Gene #31: '17q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
17Q GAIN MUTATED 18 1 4 3
17Q GAIN WILD-TYPE 352 21 13 34

Figure S74.  Get High-res Image Gene #31: '17q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'17q gain' versus 'RACE'

P value = 0.0117 (Fisher's exact test), Q value = 0.045

Table S75.  Gene #31: '17q gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
17Q GAIN MUTATED 0 0 14 0 14
17Q GAIN WILD-TYPE 4 20 92 9 354

Figure S75.  Get High-res Image Gene #31: '17q gain' versus Clinical Feature #6: 'RACE'

'18p gain' versus 'Time to Death'

P value = 0.00737 (logrank test), Q value = 0.032

Table S76.  Gene #32: '18p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
18P GAIN MUTATED 72 20 0.4 - 125.4 (29.9)
18P GAIN WILD-TYPE 462 61 0.0 - 225.5 (27.2)

Figure S76.  Get High-res Image Gene #32: '18p gain' versus Clinical Feature #1: 'Time to Death'

'18p gain' versus 'YEARS_TO_BIRTH'

P value = 0.000622 (Wilcoxon-test), Q value = 0.0038

Table S77.  Gene #32: '18p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
18P GAIN MUTATED 72 68.1 (10.2)
18P GAIN WILD-TYPE 462 63.3 (11.2)

Figure S77.  Get High-res Image Gene #32: '18p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'18p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S78.  Gene #32: '18p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
18P GAIN MUTATED 22 5 45
18P GAIN WILD-TYPE 379 17 68

Figure S78.  Get High-res Image Gene #32: '18p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'18p gain' versus 'RESIDUAL_TUMOR'

P value = 0.0183 (Fisher's exact test), Q value = 0.067

Table S79.  Gene #32: '18p gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
18P GAIN MUTATED 46 1 6 8
18P GAIN WILD-TYPE 324 21 11 29

Figure S79.  Get High-res Image Gene #32: '18p gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'18p gain' versus 'RACE'

P value = 0.00116 (Fisher's exact test), Q value = 0.0066

Table S80.  Gene #32: '18p gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
18P GAIN MUTATED 0 2 28 1 37
18P GAIN WILD-TYPE 4 18 78 8 331

Figure S80.  Get High-res Image Gene #32: '18p gain' versus Clinical Feature #6: 'RACE'

'18q gain' versus 'Time to Death'

P value = 0.000386 (logrank test), Q value = 0.0024

Table S81.  Gene #33: '18q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
18Q GAIN MUTATED 45 16 2.4 - 125.4 (27.2)
18Q GAIN WILD-TYPE 489 65 0.0 - 225.5 (27.4)

Figure S81.  Get High-res Image Gene #33: '18q gain' versus Clinical Feature #1: 'Time to Death'

'18q gain' versus 'YEARS_TO_BIRTH'

P value = 0.00745 (Wilcoxon-test), Q value = 0.032

Table S82.  Gene #33: '18q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
18Q GAIN MUTATED 45 68.4 (11.4)
18Q GAIN WILD-TYPE 489 63.6 (11.1)

Figure S82.  Get High-res Image Gene #33: '18q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'18q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S83.  Gene #33: '18q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
18Q GAIN MUTATED 17 4 24
18Q GAIN WILD-TYPE 384 18 89

Figure S83.  Get High-res Image Gene #33: '18q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'18q gain' versus 'RESIDUAL_TUMOR'

P value = 0.00684 (Fisher's exact test), Q value = 0.03

Table S84.  Gene #33: '18q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
18Q GAIN MUTATED 27 0 4 7
18Q GAIN WILD-TYPE 343 22 13 30

Figure S84.  Get High-res Image Gene #33: '18q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'19p gain' versus 'YEARS_TO_BIRTH'

P value = 2.55e-06 (Wilcoxon-test), Q value = 9.9e-05

Table S85.  Gene #34: '19p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
19P GAIN MUTATED 53 70.3 (8.6)
19P GAIN WILD-TYPE 481 63.3 (11.2)

Figure S85.  Get High-res Image Gene #34: '19p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'19p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S86.  Gene #34: '19p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
19P GAIN MUTATED 20 3 30
19P GAIN WILD-TYPE 381 19 83

Figure S86.  Get High-res Image Gene #34: '19p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'19q gain' versus 'Time to Death'

P value = 0.00151 (logrank test), Q value = 0.0083

Table S87.  Gene #35: '19q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
19Q GAIN MUTATED 55 15 0.1 - 110.1 (22.1)
19Q GAIN WILD-TYPE 479 66 0.0 - 225.5 (28.1)

Figure S87.  Get High-res Image Gene #35: '19q gain' versus Clinical Feature #1: 'Time to Death'

'19q gain' versus 'YEARS_TO_BIRTH'

P value = 2.45e-07 (Wilcoxon-test), Q value = 7e-05

Table S88.  Gene #35: '19q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
19Q GAIN MUTATED 56 70.7 (8.6)
19Q GAIN WILD-TYPE 478 63.2 (11.2)

Figure S88.  Get High-res Image Gene #35: '19q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'19q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S89.  Gene #35: '19q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
19Q GAIN MUTATED 15 3 38
19Q GAIN WILD-TYPE 386 19 75

Figure S89.  Get High-res Image Gene #35: '19q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'19q gain' versus 'RACE'

P value = 0.0405 (Fisher's exact test), Q value = 0.13

Table S90.  Gene #35: '19q gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
19Q GAIN MUTATED 0 2 20 0 31
19Q GAIN WILD-TYPE 4 18 86 9 337

Figure S90.  Get High-res Image Gene #35: '19q gain' versus Clinical Feature #6: 'RACE'

'20p gain' versus 'Time to Death'

P value = 0.000276 (logrank test), Q value = 0.0018

Table S91.  Gene #36: '20p gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
20P GAIN MUTATED 111 27 0.0 - 136.6 (23.7)
20P GAIN WILD-TYPE 423 54 0.1 - 225.5 (28.3)

Figure S91.  Get High-res Image Gene #36: '20p gain' versus Clinical Feature #1: 'Time to Death'

'20p gain' versus 'YEARS_TO_BIRTH'

P value = 6.53e-05 (Wilcoxon-test), Q value = 0.00051

Table S92.  Gene #36: '20p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
20P GAIN MUTATED 111 67.5 (10.0)
20P GAIN WILD-TYPE 423 63.1 (11.3)

Figure S92.  Get High-res Image Gene #36: '20p gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'20p gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S93.  Gene #36: '20p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
20P GAIN MUTATED 47 4 60
20P GAIN WILD-TYPE 354 18 53

Figure S93.  Get High-res Image Gene #36: '20p gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'20p gain' versus 'RESIDUAL_TUMOR'

P value = 0.045 (Fisher's exact test), Q value = 0.14

Table S94.  Gene #36: '20p gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
20P GAIN MUTATED 66 4 7 11
20P GAIN WILD-TYPE 304 18 10 26

Figure S94.  Get High-res Image Gene #36: '20p gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'20q gain' versus 'Time to Death'

P value = 1.85e-05 (logrank test), Q value = 0.00017

Table S95.  Gene #37: '20q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
20Q GAIN MUTATED 130 34 0.0 - 225.5 (24.3)
20Q GAIN WILD-TYPE 404 47 0.1 - 185.8 (28.3)

Figure S95.  Get High-res Image Gene #37: '20q gain' versus Clinical Feature #1: 'Time to Death'

'20q gain' versus 'YEARS_TO_BIRTH'

P value = 4.9e-06 (Wilcoxon-test), Q value = 9.9e-05

Table S96.  Gene #37: '20q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
20Q GAIN MUTATED 130 67.7 (9.8)
20Q GAIN WILD-TYPE 404 62.8 (11.4)

Figure S96.  Get High-res Image Gene #37: '20q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'20q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S97.  Gene #37: '20q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
20Q GAIN MUTATED 57 4 70
20Q GAIN WILD-TYPE 344 18 43

Figure S97.  Get High-res Image Gene #37: '20q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'20q gain' versus 'RESIDUAL_TUMOR'

P value = 0.0113 (Fisher's exact test), Q value = 0.044

Table S98.  Gene #37: '20q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
20Q GAIN MUTATED 76 5 9 12
20Q GAIN WILD-TYPE 294 17 8 25

Figure S98.  Get High-res Image Gene #37: '20q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'20q gain' versus 'RACE'

P value = 0.0163 (Fisher's exact test), Q value = 0.06

Table S99.  Gene #37: '20q gain' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
20Q GAIN MUTATED 1 4 38 3 75
20Q GAIN WILD-TYPE 3 16 68 6 293

Figure S99.  Get High-res Image Gene #37: '20q gain' versus Clinical Feature #6: 'RACE'

'21q gain' versus 'Time to Death'

P value = 0.0245 (logrank test), Q value = 0.086

Table S100.  Gene #38: '21q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
21Q GAIN MUTATED 38 10 0.1 - 110.1 (24.1)
21Q GAIN WILD-TYPE 496 71 0.0 - 225.5 (27.9)

Figure S100.  Get High-res Image Gene #38: '21q gain' versus Clinical Feature #1: 'Time to Death'

'21q gain' versus 'YEARS_TO_BIRTH'

P value = 0.00089 (Wilcoxon-test), Q value = 0.0052

Table S101.  Gene #38: '21q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
21Q GAIN MUTATED 38 69.6 (9.1)
21Q GAIN WILD-TYPE 496 63.6 (11.2)

Figure S101.  Get High-res Image Gene #38: '21q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'21q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S102.  Gene #38: '21q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
21Q GAIN MUTATED 12 1 25
21Q GAIN WILD-TYPE 389 21 88

Figure S102.  Get High-res Image Gene #38: '21q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'22q gain' versus 'Time to Death'

P value = 0.0297 (logrank test), Q value = 0.098

Table S103.  Gene #39: '22q gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
22Q GAIN MUTATED 30 9 0.4 - 225.5 (27.6)
22Q GAIN WILD-TYPE 504 72 0.0 - 185.8 (27.3)

Figure S103.  Get High-res Image Gene #39: '22q gain' versus Clinical Feature #1: 'Time to Death'

'22q gain' versus 'YEARS_TO_BIRTH'

P value = 0.00298 (Wilcoxon-test), Q value = 0.014

Table S104.  Gene #39: '22q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
22Q GAIN MUTATED 30 69.6 (8.3)
22Q GAIN WILD-TYPE 504 63.7 (11.3)

Figure S104.  Get High-res Image Gene #39: '22q gain' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'22q gain' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S105.  Gene #39: '22q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
22Q GAIN MUTATED 7 1 23
22Q GAIN WILD-TYPE 394 21 90

Figure S105.  Get High-res Image Gene #39: '22q gain' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'22q gain' versus 'RESIDUAL_TUMOR'

P value = 0.0319 (Fisher's exact test), Q value = 0.1

Table S106.  Gene #39: '22q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
22Q GAIN MUTATED 19 1 4 3
22Q GAIN WILD-TYPE 351 21 13 34

Figure S106.  Get High-res Image Gene #39: '22q gain' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'xq gain' versus 'Time to Death'

P value = 0.00793 (logrank test), Q value = 0.033

Table S107.  Gene #41: 'xq gain' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
XQ GAIN MUTATED 64 16 0.1 - 83.6 (23.9)
XQ GAIN WILD-TYPE 470 65 0.0 - 225.5 (27.9)

Figure S107.  Get High-res Image Gene #41: 'xq gain' versus Clinical Feature #1: 'Time to Death'

'1p loss' versus 'YEARS_TO_BIRTH'

P value = 0.0365 (Wilcoxon-test), Q value = 0.12

Table S108.  Gene #42: '1p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
1P LOSS MUTATED 25 69.1 (10.2)
1P LOSS WILD-TYPE 509 63.7 (11.2)

Figure S108.  Get High-res Image Gene #42: '1p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'1p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S109.  Gene #42: '1p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
1P LOSS MUTATED 6 3 16
1P LOSS WILD-TYPE 395 19 97

Figure S109.  Get High-res Image Gene #42: '1p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'1p loss' versus 'RESIDUAL_TUMOR'

P value = 0.00197 (Fisher's exact test), Q value = 0.01

Table S110.  Gene #42: '1p loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
1P LOSS MUTATED 15 3 4 0
1P LOSS WILD-TYPE 355 19 13 37

Figure S110.  Get High-res Image Gene #42: '1p loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'1q loss' versus 'Time to Death'

P value = 0.0804 (logrank test), Q value = 0.21

Table S111.  Gene #43: '1q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
1Q LOSS MUTATED 14 5 4.8 - 149.6 (28.0)
1Q LOSS WILD-TYPE 520 76 0.0 - 225.5 (27.4)

Figure S111.  Get High-res Image Gene #43: '1q loss' versus Clinical Feature #1: 'Time to Death'

'1q loss' versus 'HISTOLOGICAL_TYPE'

P value = 4e-05 (Fisher's exact test), Q value = 0.00034

Table S112.  Gene #43: '1q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
1Q LOSS MUTATED 3 2 9
1Q LOSS WILD-TYPE 398 20 104

Figure S112.  Get High-res Image Gene #43: '1q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'1q loss' versus 'RESIDUAL_TUMOR'

P value = 0.0185 (Fisher's exact test), Q value = 0.067

Table S113.  Gene #43: '1q loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
1Q LOSS MUTATED 9 1 3 0
1Q LOSS WILD-TYPE 361 21 14 37

Figure S113.  Get High-res Image Gene #43: '1q loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'2p loss' versus 'RADIATION_THERAPY'

P value = 0.0485 (Fisher's exact test), Q value = 0.14

Table S114.  Gene #44: '2p loss' versus Clinical Feature #3: 'RADIATION_THERAPY'

nPatients NO YES
ALL 284 218
2P LOSS MUTATED 9 1
2P LOSS WILD-TYPE 275 217

Figure S114.  Get High-res Image Gene #44: '2p loss' versus Clinical Feature #3: 'RADIATION_THERAPY'

'2q loss' versus 'Time to Death'

P value = 0.00609 (logrank test), Q value = 0.027

Table S115.  Gene #45: '2q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
2Q LOSS MUTATED 17 6 0.6 - 92.9 (22.3)
2Q LOSS WILD-TYPE 517 75 0.0 - 225.5 (27.4)

Figure S115.  Get High-res Image Gene #45: '2q loss' versus Clinical Feature #1: 'Time to Death'

'2q loss' versus 'RADIATION_THERAPY'

P value = 0.0695 (Fisher's exact test), Q value = 0.19

Table S116.  Gene #45: '2q loss' versus Clinical Feature #3: 'RADIATION_THERAPY'

nPatients NO YES
ALL 284 218
2Q LOSS MUTATED 13 3
2Q LOSS WILD-TYPE 271 215

Figure S116.  Get High-res Image Gene #45: '2q loss' versus Clinical Feature #3: 'RADIATION_THERAPY'

'3p loss' versus 'Time to Death'

P value = 0.0073 (logrank test), Q value = 0.032

Table S117.  Gene #46: '3p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
3P LOSS MUTATED 51 13 0.1 - 125.4 (22.6)
3P LOSS WILD-TYPE 483 68 0.0 - 225.5 (28.1)

Figure S117.  Get High-res Image Gene #46: '3p loss' versus Clinical Feature #1: 'Time to Death'

'3p loss' versus 'YEARS_TO_BIRTH'

P value = 0.00712 (Wilcoxon-test), Q value = 0.031

Table S118.  Gene #46: '3p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
3P LOSS MUTATED 50 67.5 (8.2)
3P LOSS WILD-TYPE 484 63.6 (11.4)

Figure S118.  Get High-res Image Gene #46: '3p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'3p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S119.  Gene #46: '3p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
3P LOSS MUTATED 19 6 26
3P LOSS WILD-TYPE 382 16 87

Figure S119.  Get High-res Image Gene #46: '3p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'3q loss' versus 'YEARS_TO_BIRTH'

P value = 0.0691 (Wilcoxon-test), Q value = 0.19

Table S120.  Gene #47: '3q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
3Q LOSS MUTATED 30 67.2 (9.0)
3Q LOSS WILD-TYPE 504 63.8 (11.3)

Figure S120.  Get High-res Image Gene #47: '3q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'3q loss' versus 'HISTOLOGICAL_TYPE'

P value = 8e-05 (Fisher's exact test), Q value = 0.00059

Table S121.  Gene #47: '3q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
3Q LOSS MUTATED 12 2 17
3Q LOSS WILD-TYPE 389 20 96

Figure S121.  Get High-res Image Gene #47: '3q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'4p loss' versus 'Time to Death'

P value = 0.00135 (logrank test), Q value = 0.0074

Table S122.  Gene #48: '4p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
4P LOSS MUTATED 103 26 0.0 - 149.6 (24.1)
4P LOSS WILD-TYPE 431 55 0.1 - 225.5 (28.1)

Figure S122.  Get High-res Image Gene #48: '4p loss' versus Clinical Feature #1: 'Time to Death'

'4p loss' versus 'YEARS_TO_BIRTH'

P value = 3.76e-05 (Wilcoxon-test), Q value = 0.00033

Table S123.  Gene #48: '4p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
4P LOSS MUTATED 104 68.0 (9.4)
4P LOSS WILD-TYPE 430 63.0 (11.4)

Figure S123.  Get High-res Image Gene #48: '4p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'4p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S124.  Gene #48: '4p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
4P LOSS MUTATED 33 7 64
4P LOSS WILD-TYPE 368 15 49

Figure S124.  Get High-res Image Gene #48: '4p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'4q loss' versus 'Time to Death'

P value = 9.24e-05 (logrank test), Q value = 0.00067

Table S125.  Gene #49: '4q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
4Q LOSS MUTATED 103 28 0.0 - 149.6 (25.5)
4Q LOSS WILD-TYPE 431 53 0.1 - 225.5 (27.9)

Figure S125.  Get High-res Image Gene #49: '4q loss' versus Clinical Feature #1: 'Time to Death'

'4q loss' versus 'YEARS_TO_BIRTH'

P value = 4.91e-05 (Wilcoxon-test), Q value = 4e-04

Table S126.  Gene #49: '4q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
4Q LOSS MUTATED 104 67.8 (9.4)
4Q LOSS WILD-TYPE 430 63.1 (11.4)

Figure S126.  Get High-res Image Gene #49: '4q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'4q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S127.  Gene #49: '4q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
4Q LOSS MUTATED 33 8 63
4Q LOSS WILD-TYPE 368 14 50

Figure S127.  Get High-res Image Gene #49: '4q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'5p loss' versus 'Time to Death'

P value = 0.00782 (logrank test), Q value = 0.033

Table S128.  Gene #50: '5p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
5P LOSS MUTATED 55 15 0.1 - 149.6 (24.1)
5P LOSS WILD-TYPE 479 66 0.0 - 225.5 (28.0)

Figure S128.  Get High-res Image Gene #50: '5p loss' versus Clinical Feature #1: 'Time to Death'

'5p loss' versus 'YEARS_TO_BIRTH'

P value = 0.097 (Wilcoxon-test), Q value = 0.24

Table S129.  Gene #50: '5p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
5P LOSS MUTATED 55 65.7 (10.0)
5P LOSS WILD-TYPE 479 63.8 (11.3)

Figure S129.  Get High-res Image Gene #50: '5p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'5p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S130.  Gene #50: '5p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
5P LOSS MUTATED 17 1 37
5P LOSS WILD-TYPE 384 21 76

Figure S130.  Get High-res Image Gene #50: '5p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'5p loss' versus 'ETHNICITY'

P value = 0.0533 (Fisher's exact test), Q value = 0.16

Table S131.  Gene #50: '5p loss' versus Clinical Feature #7: 'ETHNICITY'

nPatients HISPANIC OR LATINO NOT HISPANIC OR LATINO
ALL 15 372
5P LOSS MUTATED 4 35
5P LOSS WILD-TYPE 11 337

Figure S131.  Get High-res Image Gene #50: '5p loss' versus Clinical Feature #7: 'ETHNICITY'

'5q loss' versus 'Time to Death'

P value = 0.000996 (logrank test), Q value = 0.0058

Table S132.  Gene #51: '5q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
5Q LOSS MUTATED 74 20 0.1 - 149.6 (22.6)
5Q LOSS WILD-TYPE 460 61 0.0 - 225.5 (28.3)

Figure S132.  Get High-res Image Gene #51: '5q loss' versus Clinical Feature #1: 'Time to Death'

'5q loss' versus 'YEARS_TO_BIRTH'

P value = 0.000806 (Wilcoxon-test), Q value = 0.0048

Table S133.  Gene #51: '5q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
5Q LOSS MUTATED 74 67.5 (9.8)
5Q LOSS WILD-TYPE 460 63.4 (11.3)

Figure S133.  Get High-res Image Gene #51: '5q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'5q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S134.  Gene #51: '5q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
5Q LOSS MUTATED 20 4 50
5Q LOSS WILD-TYPE 381 18 63

Figure S134.  Get High-res Image Gene #51: '5q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'5q loss' versus 'ETHNICITY'

P value = 0.0408 (Fisher's exact test), Q value = 0.13

Table S135.  Gene #51: '5q loss' versus Clinical Feature #7: 'ETHNICITY'

nPatients HISPANIC OR LATINO NOT HISPANIC OR LATINO
ALL 15 372
5Q LOSS MUTATED 5 48
5Q LOSS WILD-TYPE 10 324

Figure S135.  Get High-res Image Gene #51: '5q loss' versus Clinical Feature #7: 'ETHNICITY'

'6p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S136.  Gene #52: '6p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
6P LOSS MUTATED 4 2 12
6P LOSS WILD-TYPE 397 20 101

Figure S136.  Get High-res Image Gene #52: '6p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'6p loss' versus 'ETHNICITY'

P value = 0.0975 (Fisher's exact test), Q value = 0.24

Table S137.  Gene #52: '6p loss' versus Clinical Feature #7: 'ETHNICITY'

nPatients HISPANIC OR LATINO NOT HISPANIC OR LATINO
ALL 15 372
6P LOSS MUTATED 2 12
6P LOSS WILD-TYPE 13 360

Figure S137.  Get High-res Image Gene #52: '6p loss' versus Clinical Feature #7: 'ETHNICITY'

'6q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S138.  Gene #53: '6q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
6Q LOSS MUTATED 5 1 19
6Q LOSS WILD-TYPE 396 21 94

Figure S138.  Get High-res Image Gene #53: '6q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'7p loss' versus 'Time to Death'

P value = 0.0104 (logrank test), Q value = 0.042

Table S139.  Gene #54: '7p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
7P LOSS MUTATED 44 13 2.1 - 110.1 (27.5)
7P LOSS WILD-TYPE 490 68 0.0 - 225.5 (27.4)

Figure S139.  Get High-res Image Gene #54: '7p loss' versus Clinical Feature #1: 'Time to Death'

'7p loss' versus 'YEARS_TO_BIRTH'

P value = 7.29e-05 (Wilcoxon-test), Q value = 0.00054

Table S140.  Gene #54: '7p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
7P LOSS MUTATED 44 69.7 (9.5)
7P LOSS WILD-TYPE 490 63.5 (11.2)

Figure S140.  Get High-res Image Gene #54: '7p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'7p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S141.  Gene #54: '7p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
7P LOSS MUTATED 15 2 27
7P LOSS WILD-TYPE 386 20 86

Figure S141.  Get High-res Image Gene #54: '7p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'7q loss' versus 'YEARS_TO_BIRTH'

P value = 0.00176 (Wilcoxon-test), Q value = 0.0093

Table S142.  Gene #55: '7q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
7Q LOSS MUTATED 42 68.6 (7.2)
7Q LOSS WILD-TYPE 492 63.6 (11.4)

Figure S142.  Get High-res Image Gene #55: '7q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'7q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S143.  Gene #55: '7q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
7Q LOSS MUTATED 9 2 31
7Q LOSS WILD-TYPE 392 20 82

Figure S143.  Get High-res Image Gene #55: '7q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'8p loss' versus 'Time to Death'

P value = 0.0441 (logrank test), Q value = 0.13

Table S144.  Gene #56: '8p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
8P LOSS MUTATED 79 17 0.4 - 110.1 (24.1)
8P LOSS WILD-TYPE 455 64 0.0 - 225.5 (28.0)

Figure S144.  Get High-res Image Gene #56: '8p loss' versus Clinical Feature #1: 'Time to Death'

'8p loss' versus 'YEARS_TO_BIRTH'

P value = 5.39e-05 (Wilcoxon-test), Q value = 0.00043

Table S145.  Gene #56: '8p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
8P LOSS MUTATED 78 68.1 (8.5)
8P LOSS WILD-TYPE 456 63.3 (11.5)

Figure S145.  Get High-res Image Gene #56: '8p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'8p loss' versus 'RADIATION_THERAPY'

P value = 0.0275 (Fisher's exact test), Q value = 0.093

Table S146.  Gene #56: '8p loss' versus Clinical Feature #3: 'RADIATION_THERAPY'

nPatients NO YES
ALL 284 218
8P LOSS MUTATED 31 39
8P LOSS WILD-TYPE 253 179

Figure S146.  Get High-res Image Gene #56: '8p loss' versus Clinical Feature #3: 'RADIATION_THERAPY'

'8p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S147.  Gene #56: '8p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
8P LOSS MUTATED 17 4 58
8P LOSS WILD-TYPE 384 18 55

Figure S147.  Get High-res Image Gene #56: '8p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'8p loss' versus 'RACE'

P value = 0.0571 (Fisher's exact test), Q value = 0.16

Table S148.  Gene #56: '8p loss' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
8P LOSS MUTATED 1 1 24 0 49
8P LOSS WILD-TYPE 3 19 82 9 319

Figure S148.  Get High-res Image Gene #56: '8p loss' versus Clinical Feature #6: 'RACE'

'8q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S149.  Gene #57: '8q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
8Q LOSS MUTATED 2 1 22
8Q LOSS WILD-TYPE 399 21 91

Figure S149.  Get High-res Image Gene #57: '8q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'9p loss' versus 'Time to Death'

P value = 0.000329 (logrank test), Q value = 0.0021

Table S150.  Gene #58: '9p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
9P LOSS MUTATED 103 29 0.3 - 149.6 (25.9)
9P LOSS WILD-TYPE 431 52 0.0 - 225.5 (28.0)

Figure S150.  Get High-res Image Gene #58: '9p loss' versus Clinical Feature #1: 'Time to Death'

'9p loss' versus 'YEARS_TO_BIRTH'

P value = 1.57e-05 (Wilcoxon-test), Q value = 0.00015

Table S151.  Gene #58: '9p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
9P LOSS MUTATED 103 67.9 (8.5)
9P LOSS WILD-TYPE 431 63.1 (11.6)

Figure S151.  Get High-res Image Gene #58: '9p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'9p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S152.  Gene #58: '9p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
9P LOSS MUTATED 36 8 59
9P LOSS WILD-TYPE 365 14 54

Figure S152.  Get High-res Image Gene #58: '9p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'9p loss' versus 'RESIDUAL_TUMOR'

P value = 0.0435 (Fisher's exact test), Q value = 0.13

Table S153.  Gene #58: '9p loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
9P LOSS MUTATED 63 5 7 10
9P LOSS WILD-TYPE 307 17 10 27

Figure S153.  Get High-res Image Gene #58: '9p loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'9q loss' versus 'Time to Death'

P value = 0.000372 (logrank test), Q value = 0.0024

Table S154.  Gene #59: '9q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
9Q LOSS MUTATED 122 32 0.0 - 136.6 (26.5)
9Q LOSS WILD-TYPE 412 49 0.1 - 225.5 (27.8)

Figure S154.  Get High-res Image Gene #59: '9q loss' versus Clinical Feature #1: 'Time to Death'

'9q loss' versus 'YEARS_TO_BIRTH'

P value = 7.35e-09 (Wilcoxon-test), Q value = 4.2e-06

Table S155.  Gene #59: '9q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
9Q LOSS MUTATED 121 68.9 (8.8)
9Q LOSS WILD-TYPE 413 62.6 (11.4)

Figure S155.  Get High-res Image Gene #59: '9q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'9q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S156.  Gene #59: '9q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
9Q LOSS MUTATED 49 9 64
9Q LOSS WILD-TYPE 352 13 49

Figure S156.  Get High-res Image Gene #59: '9q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'10p loss' versus 'Time to Death'

P value = 0.0248 (logrank test), Q value = 0.086

Table S157.  Gene #60: '10p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
10P LOSS MUTATED 43 11 0.3 - 125.4 (23.7)
10P LOSS WILD-TYPE 491 70 0.0 - 225.5 (27.9)

Figure S157.  Get High-res Image Gene #60: '10p loss' versus Clinical Feature #1: 'Time to Death'

'10p loss' versus 'YEARS_TO_BIRTH'

P value = 0.0176 (Wilcoxon-test), Q value = 0.064

Table S158.  Gene #60: '10p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
10P LOSS MUTATED 43 67.9 (8.5)
10P LOSS WILD-TYPE 491 63.6 (11.3)

Figure S158.  Get High-res Image Gene #60: '10p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'10p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S159.  Gene #60: '10p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
10P LOSS MUTATED 9 4 30
10P LOSS WILD-TYPE 392 18 83

Figure S159.  Get High-res Image Gene #60: '10p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'10q loss' versus 'YEARS_TO_BIRTH'

P value = 0.00847 (Wilcoxon-test), Q value = 0.035

Table S160.  Gene #61: '10q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
10Q LOSS MUTATED 40 68.3 (8.4)
10Q LOSS WILD-TYPE 494 63.6 (11.3)

Figure S160.  Get High-res Image Gene #61: '10q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'10q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S161.  Gene #61: '10q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
10Q LOSS MUTATED 12 5 23
10Q LOSS WILD-TYPE 389 17 90

Figure S161.  Get High-res Image Gene #61: '10q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'11p loss' versus 'Time to Death'

P value = 0.000257 (logrank test), Q value = 0.0017

Table S162.  Gene #62: '11p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
11P LOSS MUTATED 74 20 0.3 - 136.6 (21.6)
11P LOSS WILD-TYPE 460 61 0.0 - 225.5 (28.3)

Figure S162.  Get High-res Image Gene #62: '11p loss' versus Clinical Feature #1: 'Time to Death'

'11p loss' versus 'YEARS_TO_BIRTH'

P value = 0.000809 (Wilcoxon-test), Q value = 0.0048

Table S163.  Gene #62: '11p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
11P LOSS MUTATED 74 67.9 (9.6)
11P LOSS WILD-TYPE 460 63.4 (11.3)

Figure S163.  Get High-res Image Gene #62: '11p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'11p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S164.  Gene #62: '11p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
11P LOSS MUTATED 26 7 41
11P LOSS WILD-TYPE 375 15 72

Figure S164.  Get High-res Image Gene #62: '11p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'11q loss' versus 'Time to Death'

P value = 0.000787 (logrank test), Q value = 0.0048

Table S165.  Gene #63: '11q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
11Q LOSS MUTATED 72 19 0.3 - 136.6 (22.1)
11Q LOSS WILD-TYPE 462 62 0.0 - 225.5 (28.3)

Figure S165.  Get High-res Image Gene #63: '11q loss' versus Clinical Feature #1: 'Time to Death'

'11q loss' versus 'YEARS_TO_BIRTH'

P value = 0.00276 (Wilcoxon-test), Q value = 0.014

Table S166.  Gene #63: '11q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
11Q LOSS MUTATED 72 67.7 (9.8)
11Q LOSS WILD-TYPE 462 63.4 (11.3)

Figure S166.  Get High-res Image Gene #63: '11q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'11q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S167.  Gene #63: '11q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
11Q LOSS MUTATED 23 7 42
11Q LOSS WILD-TYPE 378 15 71

Figure S167.  Get High-res Image Gene #63: '11q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'12p loss' versus 'Time to Death'

P value = 0.000233 (logrank test), Q value = 0.0016

Table S168.  Gene #64: '12p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
12P LOSS MUTATED 43 15 8.2 - 118.2 (26.1)
12P LOSS WILD-TYPE 491 66 0.0 - 225.5 (27.6)

Figure S168.  Get High-res Image Gene #64: '12p loss' versus Clinical Feature #1: 'Time to Death'

'12p loss' versus 'YEARS_TO_BIRTH'

P value = 0.0593 (Wilcoxon-test), Q value = 0.17

Table S169.  Gene #64: '12p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
12P LOSS MUTATED 43 66.3 (7.9)
12P LOSS WILD-TYPE 491 63.8 (11.4)

Figure S169.  Get High-res Image Gene #64: '12p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'12p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S170.  Gene #64: '12p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
12P LOSS MUTATED 14 1 28
12P LOSS WILD-TYPE 387 21 85

Figure S170.  Get High-res Image Gene #64: '12p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'12p loss' versus 'RESIDUAL_TUMOR'

P value = 0.0605 (Fisher's exact test), Q value = 0.17

Table S171.  Gene #64: '12p loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
12P LOSS MUTATED 27 3 4 4
12P LOSS WILD-TYPE 343 19 13 33

Figure S171.  Get High-res Image Gene #64: '12p loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'12q loss' versus 'Time to Death'

P value = 0.00134 (logrank test), Q value = 0.0074

Table S172.  Gene #65: '12q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
12Q LOSS MUTATED 36 11 7.8 - 118.2 (21.9)
12Q LOSS WILD-TYPE 498 70 0.0 - 225.5 (28.0)

Figure S172.  Get High-res Image Gene #65: '12q loss' versus Clinical Feature #1: 'Time to Death'

'12q loss' versus 'YEARS_TO_BIRTH'

P value = 0.0715 (Wilcoxon-test), Q value = 0.19

Table S173.  Gene #65: '12q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
12Q LOSS MUTATED 36 66.8 (9.5)
12Q LOSS WILD-TYPE 498 63.8 (11.3)

Figure S173.  Get High-res Image Gene #65: '12q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'12q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S174.  Gene #65: '12q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
12Q LOSS MUTATED 9 1 26
12Q LOSS WILD-TYPE 392 21 87

Figure S174.  Get High-res Image Gene #65: '12q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'13q loss' versus 'Time to Death'

P value = 0.00226 (logrank test), Q value = 0.012

Table S175.  Gene #66: '13q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
13Q LOSS MUTATED 91 22 0.3 - 149.6 (22.3)
13Q LOSS WILD-TYPE 443 59 0.0 - 225.5 (28.3)

Figure S175.  Get High-res Image Gene #66: '13q loss' versus Clinical Feature #1: 'Time to Death'

'13q loss' versus 'YEARS_TO_BIRTH'

P value = 0.0106 (Wilcoxon-test), Q value = 0.042

Table S176.  Gene #66: '13q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
13Q LOSS MUTATED 91 66.7 (9.9)
13Q LOSS WILD-TYPE 443 63.4 (11.4)

Figure S176.  Get High-res Image Gene #66: '13q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'13q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S177.  Gene #66: '13q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
13Q LOSS MUTATED 48 6 38
13Q LOSS WILD-TYPE 353 16 75

Figure S177.  Get High-res Image Gene #66: '13q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'14q loss' versus 'Time to Death'

P value = 0.0017 (logrank test), Q value = 0.0091

Table S178.  Gene #67: '14q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
14Q LOSS MUTATED 60 16 0.3 - 125.4 (22.0)
14Q LOSS WILD-TYPE 474 65 0.0 - 225.5 (27.9)

Figure S178.  Get High-res Image Gene #67: '14q loss' versus Clinical Feature #1: 'Time to Death'

'14q loss' versus 'YEARS_TO_BIRTH'

P value = 0.00468 (Wilcoxon-test), Q value = 0.021

Table S179.  Gene #67: '14q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
14Q LOSS MUTATED 60 67.7 (8.6)
14Q LOSS WILD-TYPE 474 63.5 (11.4)

Figure S179.  Get High-res Image Gene #67: '14q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'14q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S180.  Gene #67: '14q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
14Q LOSS MUTATED 19 3 38
14Q LOSS WILD-TYPE 382 19 75

Figure S180.  Get High-res Image Gene #67: '14q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'14q loss' versus 'RACE'

P value = 0.0191 (Fisher's exact test), Q value = 0.068

Table S181.  Gene #67: '14q loss' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
14Q LOSS MUTATED 1 2 21 1 32
14Q LOSS WILD-TYPE 3 18 85 8 336

Figure S181.  Get High-res Image Gene #67: '14q loss' versus Clinical Feature #6: 'RACE'

'14q loss' versus 'ETHNICITY'

P value = 0.0625 (Fisher's exact test), Q value = 0.18

Table S182.  Gene #67: '14q loss' versus Clinical Feature #7: 'ETHNICITY'

nPatients HISPANIC OR LATINO NOT HISPANIC OR LATINO
ALL 15 372
14Q LOSS MUTATED 4 37
14Q LOSS WILD-TYPE 11 335

Figure S182.  Get High-res Image Gene #67: '14q loss' versus Clinical Feature #7: 'ETHNICITY'

'15q loss' versus 'Time to Death'

P value = 0.00275 (logrank test), Q value = 0.014

Table S183.  Gene #68: '15q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
15Q LOSS MUTATED 108 26 0.0 - 136.6 (22.3)
15Q LOSS WILD-TYPE 426 55 0.1 - 225.5 (29.0)

Figure S183.  Get High-res Image Gene #68: '15q loss' versus Clinical Feature #1: 'Time to Death'

'15q loss' versus 'YEARS_TO_BIRTH'

P value = 8.93e-07 (Wilcoxon-test), Q value = 9.9e-05

Table S184.  Gene #68: '15q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
15Q LOSS MUTATED 108 68.6 (10.2)
15Q LOSS WILD-TYPE 426 62.8 (11.2)

Figure S184.  Get High-res Image Gene #68: '15q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'15q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S185.  Gene #68: '15q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
15Q LOSS MUTATED 37 9 62
15Q LOSS WILD-TYPE 364 13 51

Figure S185.  Get High-res Image Gene #68: '15q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'16p loss' versus 'Time to Death'

P value = 4.34e-05 (logrank test), Q value = 0.00036

Table S186.  Gene #69: '16p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
16P LOSS MUTATED 96 26 0.1 - 110.1 (27.0)
16P LOSS WILD-TYPE 438 55 0.0 - 225.5 (27.9)

Figure S186.  Get High-res Image Gene #69: '16p loss' versus Clinical Feature #1: 'Time to Death'

'16p loss' versus 'YEARS_TO_BIRTH'

P value = 5.45e-05 (Wilcoxon-test), Q value = 0.00043

Table S187.  Gene #69: '16p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
16P LOSS MUTATED 97 67.8 (9.6)
16P LOSS WILD-TYPE 437 63.1 (11.4)

Figure S187.  Get High-res Image Gene #69: '16p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'16p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S188.  Gene #69: '16p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
16P LOSS MUTATED 33 6 58
16P LOSS WILD-TYPE 368 16 55

Figure S188.  Get High-res Image Gene #69: '16p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'16p loss' versus 'RESIDUAL_TUMOR'

P value = 0.0109 (Fisher's exact test), Q value = 0.043

Table S189.  Gene #69: '16p loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
16P LOSS MUTATED 55 5 7 10
16P LOSS WILD-TYPE 315 17 10 27

Figure S189.  Get High-res Image Gene #69: '16p loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'16q loss' versus 'Time to Death'

P value = 0.00273 (logrank test), Q value = 0.014

Table S190.  Gene #70: '16q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
16Q LOSS MUTATED 137 31 0.1 - 123.7 (25.9)
16Q LOSS WILD-TYPE 397 50 0.0 - 225.5 (28.3)

Figure S190.  Get High-res Image Gene #70: '16q loss' versus Clinical Feature #1: 'Time to Death'

'16q loss' versus 'YEARS_TO_BIRTH'

P value = 5.53e-07 (Wilcoxon-test), Q value = 9.9e-05

Table S191.  Gene #70: '16q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
16Q LOSS MUTATED 138 67.8 (9.3)
16Q LOSS WILD-TYPE 396 62.7 (11.5)

Figure S191.  Get High-res Image Gene #70: '16q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'16q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S192.  Gene #70: '16q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
16Q LOSS MUTATED 56 7 75
16Q LOSS WILD-TYPE 345 15 38

Figure S192.  Get High-res Image Gene #70: '16q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'16q loss' versus 'RESIDUAL_TUMOR'

P value = 0.0162 (Fisher's exact test), Q value = 0.06

Table S193.  Gene #70: '16q loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
16Q LOSS MUTATED 80 8 8 13
16Q LOSS WILD-TYPE 290 14 9 24

Figure S193.  Get High-res Image Gene #70: '16q loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'16q loss' versus 'RACE'

P value = 0.0655 (Fisher's exact test), Q value = 0.18

Table S194.  Gene #70: '16q loss' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
16Q LOSS MUTATED 1 2 37 2 86
16Q LOSS WILD-TYPE 3 18 69 7 282

Figure S194.  Get High-res Image Gene #70: '16q loss' versus Clinical Feature #6: 'RACE'

'17p loss' versus 'Time to Death'

P value = 9.65e-05 (logrank test), Q value = 0.00069

Table S195.  Gene #71: '17p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
17P LOSS MUTATED 128 33 0.1 - 136.6 (23.8)
17P LOSS WILD-TYPE 406 48 0.0 - 225.5 (28.0)

Figure S195.  Get High-res Image Gene #71: '17p loss' versus Clinical Feature #1: 'Time to Death'

'17p loss' versus 'YEARS_TO_BIRTH'

P value = 3.49e-06 (Wilcoxon-test), Q value = 9.9e-05

Table S196.  Gene #71: '17p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
17P LOSS MUTATED 128 67.7 (9.0)
17P LOSS WILD-TYPE 406 62.8 (11.6)

Figure S196.  Get High-res Image Gene #71: '17p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'17p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S197.  Gene #71: '17p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
17P LOSS MUTATED 46 10 73
17P LOSS WILD-TYPE 355 12 40

Figure S197.  Get High-res Image Gene #71: '17p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'17p loss' versus 'RACE'

P value = 0.0126 (Fisher's exact test), Q value = 0.048

Table S198.  Gene #71: '17p loss' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 20 106 9 368
17P LOSS MUTATED 1 1 36 3 79
17P LOSS WILD-TYPE 3 19 70 6 289

Figure S198.  Get High-res Image Gene #71: '17p loss' versus Clinical Feature #6: 'RACE'

'17q loss' versus 'Time to Death'

P value = 0.003 (logrank test), Q value = 0.014

Table S199.  Gene #72: '17q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
17Q LOSS MUTATED 91 24 0.1 - 136.6 (25.5)
17Q LOSS WILD-TYPE 443 57 0.0 - 225.5 (27.4)

Figure S199.  Get High-res Image Gene #72: '17q loss' versus Clinical Feature #1: 'Time to Death'

'17q loss' versus 'YEARS_TO_BIRTH'

P value = 7.09e-05 (Wilcoxon-test), Q value = 0.00054

Table S200.  Gene #72: '17q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
17Q LOSS MUTATED 92 67.9 (9.7)
17Q LOSS WILD-TYPE 442 63.2 (11.3)

Figure S200.  Get High-res Image Gene #72: '17q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'17q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S201.  Gene #72: '17q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
17Q LOSS MUTATED 37 8 47
17Q LOSS WILD-TYPE 364 14 66

Figure S201.  Get High-res Image Gene #72: '17q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'17q loss' versus 'ETHNICITY'

P value = 0.0297 (Fisher's exact test), Q value = 0.098

Table S202.  Gene #72: '17q loss' versus Clinical Feature #7: 'ETHNICITY'

nPatients HISPANIC OR LATINO NOT HISPANIC OR LATINO
ALL 15 372
17Q LOSS MUTATED 6 61
17Q LOSS WILD-TYPE 9 311

Figure S202.  Get High-res Image Gene #72: '17q loss' versus Clinical Feature #7: 'ETHNICITY'

'18p loss' versus 'Time to Death'

P value = 0.0629 (logrank test), Q value = 0.18

Table S203.  Gene #73: '18p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
18P LOSS MUTATED 50 11 0.1 - 136.6 (22.2)
18P LOSS WILD-TYPE 484 70 0.0 - 225.5 (27.9)

Figure S203.  Get High-res Image Gene #73: '18p loss' versus Clinical Feature #1: 'Time to Death'

'18p loss' versus 'YEARS_TO_BIRTH'

P value = 0.0242 (Wilcoxon-test), Q value = 0.085

Table S204.  Gene #73: '18p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
18P LOSS MUTATED 51 66.6 (10.3)
18P LOSS WILD-TYPE 483 63.7 (11.3)

Figure S204.  Get High-res Image Gene #73: '18p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'18p loss' versus 'HISTOLOGICAL_TYPE'

P value = 7e-05 (Fisher's exact test), Q value = 0.00054

Table S205.  Gene #73: '18p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
18P LOSS MUTATED 25 5 21
18P LOSS WILD-TYPE 376 17 92

Figure S205.  Get High-res Image Gene #73: '18p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'18q loss' versus 'Time to Death'

P value = 0.0481 (logrank test), Q value = 0.14

Table S206.  Gene #74: '18q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
18Q LOSS MUTATED 63 14 0.1 - 136.6 (22.4)
18Q LOSS WILD-TYPE 471 67 0.0 - 225.5 (27.9)

Figure S206.  Get High-res Image Gene #74: '18q loss' versus Clinical Feature #1: 'Time to Death'

'18q loss' versus 'YEARS_TO_BIRTH'

P value = 0.0226 (Wilcoxon-test), Q value = 0.081

Table S207.  Gene #74: '18q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
18Q LOSS MUTATED 64 66.4 (9.6)
18Q LOSS WILD-TYPE 470 63.7 (11.4)

Figure S207.  Get High-res Image Gene #74: '18q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'18q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S208.  Gene #74: '18q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
18Q LOSS MUTATED 28 6 30
18Q LOSS WILD-TYPE 373 16 83

Figure S208.  Get High-res Image Gene #74: '18q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'18q loss' versus 'RESIDUAL_TUMOR'

P value = 0.0795 (Fisher's exact test), Q value = 0.21

Table S209.  Gene #74: '18q loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
18Q LOSS MUTATED 38 5 3 7
18Q LOSS WILD-TYPE 332 17 14 30

Figure S209.  Get High-res Image Gene #74: '18q loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'19p loss' versus 'Time to Death'

P value = 0.00022 (logrank test), Q value = 0.0015

Table S210.  Gene #75: '19p loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
19P LOSS MUTATED 59 18 0.1 - 136.6 (25.5)
19P LOSS WILD-TYPE 475 63 0.0 - 225.5 (27.9)

Figure S210.  Get High-res Image Gene #75: '19p loss' versus Clinical Feature #1: 'Time to Death'

'19p loss' versus 'YEARS_TO_BIRTH'

P value = 0.0951 (Wilcoxon-test), Q value = 0.24

Table S211.  Gene #75: '19p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
19P LOSS MUTATED 58 66.0 (10.2)
19P LOSS WILD-TYPE 476 63.7 (11.3)

Figure S211.  Get High-res Image Gene #75: '19p loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'19p loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S212.  Gene #75: '19p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
19P LOSS MUTATED 18 4 37
19P LOSS WILD-TYPE 383 18 76

Figure S212.  Get High-res Image Gene #75: '19p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'19p loss' versus 'RESIDUAL_TUMOR'

P value = 0.0914 (Fisher's exact test), Q value = 0.23

Table S213.  Gene #75: '19p loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

nPatients R0 R1 R2 RX
ALL 370 22 17 37
19P LOSS MUTATED 34 4 4 5
19P LOSS WILD-TYPE 336 18 13 32

Figure S213.  Get High-res Image Gene #75: '19p loss' versus Clinical Feature #5: 'RESIDUAL_TUMOR'

'19q loss' versus 'Time to Death'

P value = 0.00175 (logrank test), Q value = 0.0093

Table S214.  Gene #76: '19q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
19Q LOSS MUTATED 56 17 0.1 - 136.6 (26.4)
19Q LOSS WILD-TYPE 478 64 0.0 - 225.5 (27.5)

Figure S214.  Get High-res Image Gene #76: '19q loss' versus Clinical Feature #1: 'Time to Death'

'19q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S215.  Gene #76: '19q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
19Q LOSS MUTATED 18 4 34
19Q LOSS WILD-TYPE 383 18 79

Figure S215.  Get High-res Image Gene #76: '19q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'20p loss' versus 'HISTOLOGICAL_TYPE'

P value = 0.00291 (Fisher's exact test), Q value = 0.014

Table S216.  Gene #77: '20p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
20P LOSS MUTATED 8 1 10
20P LOSS WILD-TYPE 393 21 103

Figure S216.  Get High-res Image Gene #77: '20p loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'20q loss' versus 'RADIATION_THERAPY'

P value = 0.0448 (Fisher's exact test), Q value = 0.14

Table S217.  Gene #78: '20q loss' versus Clinical Feature #3: 'RADIATION_THERAPY'

nPatients NO YES
ALL 284 218
20Q LOSS MUTATED 2 7
20Q LOSS WILD-TYPE 282 211

Figure S217.  Get High-res Image Gene #78: '20q loss' versus Clinical Feature #3: 'RADIATION_THERAPY'

'20q loss' versus 'HISTOLOGICAL_TYPE'

P value = 0.00717 (Fisher's exact test), Q value = 0.031

Table S218.  Gene #78: '20q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
20Q LOSS MUTATED 3 2 4
20Q LOSS WILD-TYPE 398 20 109

Figure S218.  Get High-res Image Gene #78: '20q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'21q loss' versus 'Time to Death'

P value = 0.0522 (logrank test), Q value = 0.15

Table S219.  Gene #79: '21q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
21Q LOSS MUTATED 54 12 0.3 - 125.4 (21.9)
21Q LOSS WILD-TYPE 480 69 0.0 - 225.5 (28.0)

Figure S219.  Get High-res Image Gene #79: '21q loss' versus Clinical Feature #1: 'Time to Death'

'21q loss' versus 'YEARS_TO_BIRTH'

P value = 0.00453 (Wilcoxon-test), Q value = 0.021

Table S220.  Gene #79: '21q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
21Q LOSS MUTATED 54 67.9 (9.7)
21Q LOSS WILD-TYPE 480 63.5 (11.3)

Figure S220.  Get High-res Image Gene #79: '21q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'21q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S221.  Gene #79: '21q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
21Q LOSS MUTATED 20 4 30
21Q LOSS WILD-TYPE 381 18 83

Figure S221.  Get High-res Image Gene #79: '21q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'22q loss' versus 'Time to Death'

P value = 0.00443 (logrank test), Q value = 0.02

Table S222.  Gene #80: '22q loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
22Q LOSS MUTATED 107 24 0.1 - 136.6 (22.6)
22Q LOSS WILD-TYPE 427 57 0.0 - 225.5 (28.3)

Figure S222.  Get High-res Image Gene #80: '22q loss' versus Clinical Feature #1: 'Time to Death'

'22q loss' versus 'YEARS_TO_BIRTH'

P value = 3.94e-05 (Wilcoxon-test), Q value = 0.00034

Table S223.  Gene #80: '22q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
22Q LOSS MUTATED 107 67.8 (8.9)
22Q LOSS WILD-TYPE 427 63.0 (11.5)

Figure S223.  Get High-res Image Gene #80: '22q loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'22q loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S224.  Gene #80: '22q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
22Q LOSS MUTATED 46 10 52
22Q LOSS WILD-TYPE 355 12 61

Figure S224.  Get High-res Image Gene #80: '22q loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'xp loss' versus 'Time to Death'

P value = 2.3e-05 (logrank test), Q value = 0.00021

Table S225.  Gene #81: 'xp loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
XP LOSS MUTATED 83 25 0.3 - 118.2 (23.2)
XP LOSS WILD-TYPE 451 56 0.0 - 225.5 (28.3)

Figure S225.  Get High-res Image Gene #81: 'xp loss' versus Clinical Feature #1: 'Time to Death'

'xp loss' versus 'YEARS_TO_BIRTH'

P value = 0.000119 (Wilcoxon-test), Q value = 0.00084

Table S226.  Gene #81: 'xp loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
XP LOSS MUTATED 83 68.0 (9.5)
XP LOSS WILD-TYPE 451 63.3 (11.3)

Figure S226.  Get High-res Image Gene #81: 'xp loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'xp loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S227.  Gene #81: 'xp loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
XP LOSS MUTATED 33 5 46
XP LOSS WILD-TYPE 368 17 67

Figure S227.  Get High-res Image Gene #81: 'xp loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'xp loss' versus 'ETHNICITY'

P value = 0.0786 (Fisher's exact test), Q value = 0.21

Table S228.  Gene #81: 'xp loss' versus Clinical Feature #7: 'ETHNICITY'

nPatients HISPANIC OR LATINO NOT HISPANIC OR LATINO
ALL 15 372
XP LOSS MUTATED 5 58
XP LOSS WILD-TYPE 10 314

Figure S228.  Get High-res Image Gene #81: 'xp loss' versus Clinical Feature #7: 'ETHNICITY'

'xq loss' versus 'Time to Death'

P value = 0.00287 (logrank test), Q value = 0.014

Table S229.  Gene #82: 'xq loss' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 534 81 0.0 - 225.5 (27.4)
XQ LOSS MUTATED 70 19 0.3 - 118.2 (25.0)
XQ LOSS WILD-TYPE 464 62 0.0 - 225.5 (27.5)

Figure S229.  Get High-res Image Gene #82: 'xq loss' versus Clinical Feature #1: 'Time to Death'

'xq loss' versus 'YEARS_TO_BIRTH'

P value = 0.000225 (Wilcoxon-test), Q value = 0.0015

Table S230.  Gene #82: 'xq loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 534 64.0 (11.2)
XQ LOSS MUTATED 70 68.4 (9.5)
XQ LOSS WILD-TYPE 464 63.3 (11.3)

Figure S230.  Get High-res Image Gene #82: 'xq loss' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'xq loss' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 9.9e-05

Table S231.  Gene #82: 'xq loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 401 22 113
XQ LOSS MUTATED 31 4 36
XQ LOSS WILD-TYPE 370 18 77

Figure S231.  Get High-res Image Gene #82: 'xq loss' versus Clinical Feature #4: 'HISTOLOGICAL_TYPE'

'xq loss' versus 'ETHNICITY'

P value = 0.0471 (Fisher's exact test), Q value = 0.14

Table S232.  Gene #82: 'xq loss' versus Clinical Feature #7: 'ETHNICITY'

nPatients HISPANIC OR LATINO NOT HISPANIC OR LATINO
ALL 15 372
XQ LOSS MUTATED 5 50
XQ LOSS WILD-TYPE 10 322

Figure S232.  Get High-res Image Gene #82: 'xq loss' versus Clinical Feature #7: 'ETHNICITY'

Methods & Data
Input

  • Copy number data file = broad_values_by_arm.txt from GISTIC pipeline

  • Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/UCEC-TP/19782702/transformed.cor.cli.txt

  • Clinical data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/Append_Data/UCEC-TP/19775642/UCEC-TP.merged_data.txt

  • Number of patients = 536

  • Number of significantly arm-level cnvs = 82

  • Number of selected clinical features = 7

  • Exclude regions that fewer than K tumors have mutations, K = 3

Survival analysis

For survival clinical features, the Kaplan-Meier survival curves of tumors with and without gene mutations were plotted and the statistical significance P values were estimated by logrank test (Bland and Altman 2004) using the 'survdiff' function in R

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

Download Results

In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.

References
[1] Bland and Altman, Statistics notes: The logrank test, BMJ 328(7447):1073 (2004)
[2] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)
[3] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)
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