Correlation between gene mutation status and molecular subtypes

Uterine Corpus Endometrioid Carcinoma (Primary solid tumor)

21 August 2015 | analyses__2015_08_21

Maintainer Information

Citation Information

Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)

Cite as Broad Institute TCGA Genome Data Analysis Center (2015): Correlation between gene mutation status and molecular subtypes. Broad Institute of MIT and Harvard. doi:10.7908/C1G44PMN

Overview

Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 197 genes and 12 molecular subtypes across 248 patients, 241 significant findings detected with P value < 0.05 and Q value < 0.25.

PTEN mutation correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
PIK3R1 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
TP53 mutation correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
CTCF mutation correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
FBXW7 mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_CHIERARCHICAL'.
ARID1A mutation correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
ARHGAP35 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
KRAS mutation correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
CTNNB1 mutation correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
ZFHX3 mutation correlated to 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
TCP11L2 mutation correlated to 'MRNA_CHIERARCHICAL' and 'MRNASEQ_CHIERARCHICAL'.
VPS11 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
PPP2R1A mutation correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
EP300 mutation correlated to 'CN_CNMF'.
KLHL8 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
GNPTAB mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
SIN3A mutation correlated to 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
ARID5B mutation correlated to 'CN_CNMF'.
NFE2L2 mutation correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
ZNF471 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
MORC4 mutation correlated to 'MIRSEQ_CNMF'.
SELP mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
RBMX mutation correlated to 'MIRSEQ_CHIERARCHICAL'.
FAT1 mutation correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
MARK3 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
RBBP6 mutation correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
ZNF263 mutation correlated to 'RPPA_CNMF'.
INTS7 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
L1TD1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
NAT1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
JAKMIP2 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
ING1 mutation correlated to 'MIRSEQ_MATURE_CNMF'.
ZNF781 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
MKI67 mutation correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
BCOR mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
DNER mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
CUX1 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
CDK17 mutation correlated to 'MRNA_CHIERARCHICAL'.
USP28 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
MSH6 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
C14ORF166B mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
ATM mutation correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
RAE1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
POLE mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
AHCYL1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
ZNF334 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
SACS mutation correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', and 'MRNASEQ_CHIERARCHICAL'.
SLC26A8 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
KIF20B mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
NFE2L3 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
FAM65B mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
RNF43 mutation correlated to 'MRNA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
TIGD4 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
FILIP1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
UFSP2 mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CNMF'.
WBP4 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
TRIM59 mutation correlated to 'MIRSEQ_MATURE_CHIERARCHICAL'.
RSBN1L mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
LNX2 mutation correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
ALPK2 mutation correlated to 'MRNA_CHIERARCHICAL' and 'MRNASEQ_CHIERARCHICAL'.
REV3L mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
CAB39L mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
INPP4B mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
C1ORF100 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
IL20 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
TAP1 mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_CHIERARCHICAL'.
RHBDD3 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
BRDT mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
RB1 mutation correlated to 'MRNA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
MFAP5 mutation correlated to 'RPPA_CHIERARCHICAL' and 'MRNASEQ_CHIERARCHICAL'.
NAA15 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
ZRANB3 mutation correlated to 'RPPA_CHIERARCHICAL' and 'MRNASEQ_CHIERARCHICAL'.
CCDC147 mutation correlated to 'RPPA_CHIERARCHICAL' and 'MRNASEQ_CHIERARCHICAL'.
ZNF662 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
PSMC4 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
PPIL4 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
CCDC144A mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
TUBGCP6 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
COL8A1 mutation correlated to 'RPPA_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
PER3 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
MGA mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_CHIERARCHICAL'.
ZNF674 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
ZNF606 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
LETMD1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
ZNF721 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
AGXT2 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
DYM mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
TAB3 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
ZNF649 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
FN1 mutation correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
KIF21A mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
EXOSC9 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
ZKSCAN1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
OR8B8 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
SENP7 mutation correlated to 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
NRIP1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
MCTP1 mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CNMF'.
CCDC146 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
PTPN12 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
RIOK3 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
CASP8 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
GFAP mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_CHIERARCHICAL'.
DENND3 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
CHEK2 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
ZMYM2 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
FOXJ3 mutation correlated to 'MRNASEQ_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
EFCAB4B mutation correlated to 'RPPA_CNMF'.
LIMA1 mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_CHIERARCHICAL'.
PPIG mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
TPX2 mutation correlated to 'MIRSEQ_CNMF'.
PARG mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
PSMD3 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
STRN3 mutation correlated to 'MIRSEQ_CNMF'.
MLL4 mutation correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
MSN mutation correlated to 'METHLYATION_CNMF'.
RBL2 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
PDGFRA mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
MORC3 mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_CHIERARCHICAL'.
CCDC82 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
NOC3L mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
ASXL2 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
THAP5 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
ZNF611 mutation correlated to 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
ZCCHC18 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
PRKCE mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
BMP2K mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
PRPF38B mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
LGMN mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
EMR1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
OR5AK2 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
ZNF534 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
FAM122A mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

Results

Overview of the results

Table 1. Get Full Table Overview of the association between mutation status of 197 genes and 12 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 241 significant findings detected.


		Clinical Features	MRNA CNMF	MRNA CHIERARCHICAL	CN CNMF	METHLYATION CNMF	RPPA CNMF	RPPA CHIERARCHICAL	MRNASEQ CNMF	MRNASEQ CHIERARCHICAL	MIRSEQ CNMF	MIRSEQ CHIERARCHICAL	MIRSEQ MATURE CNMF	MIRSEQ MATURE CHIERARCHICAL
	nMutated (%)	nWild-Type	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test
PTEN	161 (65%)	87	0.00442 (0.0812)	2e-05 (0.00143)	1e-05 (0.000815)	1e-05 (0.000815)	2e-05 (0.00143)	1e-05 (0.000815)	1e-05 (0.000815)	1e-05 (0.000815)	1e-05 (0.000815)	1e-05 (0.000815)	1e-05 (0.000815)	1e-05 (0.000815)
TP53	69 (28%)	179	2e-05 (0.00143)	1e-05 (0.000815)	1e-05 (0.000815)	1e-05 (0.000815)	2e-05 (0.00143)	1e-05 (0.000815)	1e-05 (0.000815)	1e-05 (0.000815)	1e-05 (0.000815)	1e-05 (0.000815)	1e-05 (0.000815)	1e-05 (0.000815)
CTNNB1	74 (30%)	174	1e-05 (0.000815)	3e-05 (0.00203)	1e-05 (0.000815)	0.00295 (0.0611)	0.375 (0.773)	0.207 (0.603)	1e-05 (0.000815)	1e-05 (0.000815)	1e-05 (0.000815)	1e-05 (0.000815)	0.00028 (0.011)	0.00226 (0.0519)
CTCF	44 (18%)	204	0.15 (0.555)	0.203 (0.6)	5e-05 (0.00311)	0.0657 (0.394)	0.00684 (0.107)	0.0227 (0.231)	0.00029 (0.0111)	0.00126 (0.0338)	0.00645 (0.102)	0.00974 (0.14)	0.0293 (0.27)	0.0189 (0.21)
PPP2R1A	28 (11%)	220	0.0744 (0.426)	0.0555 (0.361)	0.0828 (0.439)	0.0142 (0.183)	0.126 (0.529)	0.065 (0.394)	0.00315 (0.0636)	0.0224 (0.231)	0.0162 (0.191)	0.001 (0.0288)	0.0107 (0.152)	0.0315 (0.283)
PIK3R1	82 (33%)	166	0.0663 (0.396)	0.0596 (0.38)	0.00034 (0.0126)	3e-05 (0.00203)	0.00555 (0.0924)	0.117 (0.518)	0.00017 (0.00804)	0.00022 (0.00963)	0.0396 (0.31)	0.0296 (0.271)	0.032 (0.286)	0.132 (0.532)
FAT1	40 (16%)	208	0.00618 (0.0994)	0.00146 (0.0383)	0.0678 (0.401)	0.00599 (0.097)	0.372 (0.773)	0.0719 (0.416)	0.167 (0.577)	0.0001 (0.00537)	0.879 (1.00)	0.00641 (0.102)	1 (1.00)	0.449 (0.811)
MKI67	29 (12%)	219	0.0234 (0.235)	0.0157 (0.187)	0.00163 (0.0414)	0.323 (0.734)	0.254 (0.674)	0.672 (0.97)	0.0643 (0.391)	0.00013 (0.00654)	0.133 (0.532)	0.0431 (0.318)	1 (1.00)	0.0249 (0.246)
ARID1A	83 (33%)	165	0.266 (0.694)	0.0722 (0.417)	1e-05 (0.000815)	0.104 (0.489)	0.0558 (0.361)	0.31 (0.724)	0.0214 (0.226)	1e-05 (0.000815)	0.0533 (0.354)	0.0002 (0.00892)	0.14 (0.541)	0.129 (0.532)
KRAS	52 (21%)	196	0.399 (0.774)	0.0354 (0.297)	0.00027 (0.011)	0.0529 (0.354)	0.0586 (0.374)	0.371 (0.773)	0.217 (0.622)	0.00028 (0.011)	0.0148 (0.187)	0.015 (0.187)	0.706 (0.982)	0.181 (0.586)
RBBP6	22 (9%)	226	0.581 (0.905)	0.0212 (0.226)	0.0127 (0.172)	0.926 (1.00)	0.671 (0.97)	0.728 (0.992)	0.0498 (0.341)	0.00012 (0.00617)	0.774 (1.00)	0.00431 (0.0809)	0.0344 (0.297)	0.0321 (0.286)
ATM	29 (12%)	219	0.0118 (0.166)	0.00028 (0.011)	0.00561 (0.0927)	0.692 (0.973)	0.831 (1.00)	0.535 (0.876)	0.706 (0.982)	0.00054 (0.018)	0.533 (0.876)	0.312 (0.724)	0.172 (0.578)	0.127 (0.531)
ZFHX3	44 (18%)	204	0.374 (0.773)	0.181 (0.586)	0.0331 (0.29)	0.0146 (0.186)	0.221 (0.629)	0.802 (1.00)	0.837 (1.00)	0.00725 (0.111)	0.162 (0.576)	0.0227 (0.231)	0.598 (0.92)	0.526 (0.872)
SIN3A	21 (8%)	227			0.0287 (0.268)	0.329 (0.739)	0.321 (0.732)	0.0787 (0.427)	0.00947 (0.137)	0.00023 (0.00989)	0.0453 (0.326)	0.00029 (0.0111)	0.499 (0.852)	0.418 (0.792)
NFE2L2	14 (6%)	234	0.0904 (0.457)	0.32 (0.731)	0.0191 (0.21)	0.183 (0.586)	0.275 (0.696)	0.0543 (0.357)	0.00144 (0.0382)	0.0186 (0.21)	0.125 (0.528)	0.0474 (0.334)	0.283 (0.696)	0.178 (0.585)
BCOR	30 (12%)	218	0.69 (0.971)	0.203 (0.6)	0.00176 (0.0433)	0.0164 (0.192)	0.195 (0.592)	0.317 (0.731)	0.0328 (0.29)	0.00443 (0.0812)	0.907 (1.00)	0.237 (0.651)	0.303 (0.715)	0.93 (1.00)
SACS	26 (10%)	222	0.0206 (0.22)	0.00156 (0.0401)	0.0344 (0.297)	0.686 (0.97)	0.57 (0.894)	0.772 (1.00)	0.221 (0.629)	0.00168 (0.0418)	0.211 (0.61)	0.0888 (0.457)	0.877 (1.00)	0.288 (0.697)
RNF43	12 (5%)	236	0.132 (0.532)	0.00961 (0.139)	0.15 (0.554)	0.447 (0.81)	0.297 (0.708)	0.494 (0.85)	0.0426 (0.318)	5e-05 (0.00311)	0.0653 (0.394)	0.0124 (0.171)	0.183 (0.586)	0.0362 (0.298)
LNX2	14 (6%)	234	0.38 (0.773)	0.281 (0.696)	0.121 (0.521)	0.00271 (0.0577)	0.933 (1.00)	0.381 (0.773)	0.0237 (0.235)	0.00296 (0.0611)	0.426 (0.792)	0.185 (0.586)	1 (1.00)	0.467 (0.824)
RB1	20 (8%)	228	0.638 (0.949)	0.00568 (0.0931)	0.428 (0.793)	0.256 (0.676)	0.501 (0.855)	0.512 (0.867)	0.473 (0.83)	7e-05 (0.00404)	0.163 (0.577)	0.0226 (0.231)	0.805 (1.00)	0.172 (0.578)
FN1	24 (10%)	224	0.183 (0.586)	0.0604 (0.381)	0.0156 (0.187)	0.411 (0.789)	0.355 (0.773)	0.522 (0.87)	0.118 (0.519)	1e-05 (0.000815)	0.268 (0.695)	0.0129 (0.174)	0.556 (0.889)	0.0841 (0.443)
SENP7	12 (5%)	236	0.376 (0.773)	0.0355 (0.297)	0.147 (0.554)	0.441 (0.805)	0.926 (1.00)	0.664 (0.969)	0.0151 (0.187)	6e-05 (0.00355)	0.121 (0.521)	0.0123 (0.17)
MLL4	30 (12%)	218	0.685 (0.97)	0.0915 (0.457)	0.0015 (0.039)	0.0393 (0.31)	0.233 (0.644)	0.15 (0.554)	0.459 (0.819)	0.00058 (0.019)	0.158 (0.569)	0.0122 (0.169)	0.377 (0.773)	0.718 (0.985)
ZNF611	12 (5%)	236	1 (1.00)	0.0786 (0.427)	0.51 (0.865)	0.138 (0.538)	0.802 (1.00)	0.0998 (0.476)	0.468 (0.824)	0.003 (0.0611)	0.189 (0.587)	0.0125 (0.171)	0.17 (0.577)	0.011 (0.156)
FBXW7	38 (15%)	210	0.342 (0.756)	0.271 (0.696)	0.309 (0.723)	0.0353 (0.297)	0.249 (0.666)	0.479 (0.837)	0.0455 (0.326)	0.00345 (0.0685)	0.756 (1.00)	0.00571 (0.0931)	0.231 (0.643)	0.0674 (0.401)
TCP11L2	14 (6%)	234	0.0414 (0.316)	0.0187 (0.21)	0.121 (0.521)	0.108 (0.501)	0.756 (1.00)	0.647 (0.959)	0.274 (0.696)	0.00015 (0.00724)	0.423 (0.792)	0.376 (0.773)	0.805 (1.00)	0.815 (1.00)
CUX1	21 (8%)	227	1 (1.00)	0.654 (0.963)	0.0223 (0.231)	0.199 (0.597)	0.129 (0.532)	0.787 (1.00)	0.255 (0.674)	0.00258 (0.0559)	0.34 (0.754)	0.167 (0.577)	0.704 (0.981)	0.415 (0.792)
KIF20B	21 (8%)	227	0.29 (0.697)	0.0431 (0.318)	0.0222 (0.231)	0.803 (1.00)	0.318 (0.731)	0.419 (0.792)	0.579 (0.905)	0.00015 (0.00724)	0.488 (0.845)	0.0482 (0.334)	0.272 (0.696)	0.327 (0.737)
UFSP2	11 (4%)	237	0.536 (0.876)	0.249 (0.666)	0.158 (0.569)	0.32 (0.731)	0.632 (0.946)	0.664 (0.969)	0.21 (0.61)	8e-05 (0.0045)	0.4 (0.774)	0.0789 (0.427)	0.0185 (0.21)	0.0356 (0.297)
ALPK2	19 (8%)	229	0.0315 (0.283)	0.0147 (0.186)	0.0322 (0.286)	0.425 (0.792)	0.217 (0.622)	0.355 (0.773)	0.246 (0.664)	0.00369 (0.0727)	0.597 (0.92)	0.58 (0.905)	0.403 (0.776)	0.532 (0.876)
TAP1	8 (3%)	240			0.197 (0.593)	0.779 (1.00)	1 (1.00)	0.676 (0.97)	0.123 (0.525)	0.00258 (0.0559)	0.338 (0.752)	0.0254 (0.249)
MFAP5	9 (4%)	239			0.374 (0.773)	0.518 (0.87)	0.391 (0.774)	0.0163 (0.191)	0.642 (0.953)	0.00323 (0.0647)	0.196 (0.593)	0.32 (0.731)	0.0417 (0.316)	0.183 (0.586)
ZRANB3	7 (3%)	241			0.431 (0.795)		1 (1.00)	0.00831 (0.124)	0.148 (0.554)	0.00456 (0.0829)	0.113 (0.508)	0.329 (0.739)
CCDC147	15 (6%)	233	0.683 (0.97)	0.0907 (0.457)	0.11 (0.505)	0.66 (0.965)	0.344 (0.759)	0.0131 (0.175)	0.537 (0.876)	0.00019 (0.00864)	0.655 (0.963)	0.233 (0.644)	0.362 (0.773)	0.0765 (0.427)
COL8A1	10 (4%)	238	0.163 (0.577)	0.139 (0.539)	0.167 (0.577)	0.443 (0.808)	0.0189 (0.21)	0.312 (0.724)	0.262 (0.686)	0.0136 (0.177)	0.142 (0.546)	0.0795 (0.427)	0.0422 (0.316)	0.169 (0.577)
MGA	26 (10%)	222	0.325 (0.736)	0.365 (0.773)	0.548 (0.886)	0.874 (1.00)	0.671 (0.97)	0.163 (0.577)	0.0274 (0.26)	0.00224 (0.0519)	0.125 (0.529)	0.00924 (0.135)	0.0967 (0.468)	0.042 (0.316)
MCTP1	13 (5%)	235	0.383 (0.773)	0.229 (0.64)	0.566 (0.892)	0.669 (0.97)	0.8 (1.00)	0.731 (0.994)	0.522 (0.87)	0.0214 (0.226)	0.189 (0.587)	0.786 (1.00)	0.0193 (0.21)	0.0356 (0.297)
GFAP	6 (2%)	242			0.425 (0.792)	0.557 (0.889)	0.0519 (0.352)	0.196 (0.593)	0.22 (0.628)	0.0156 (0.187)	0.285 (0.696)	0.0216 (0.227)
FOXJ3	10 (4%)	238	0.38 (0.773)	0.281 (0.696)	0.349 (0.766)	0.777 (1.00)	0.394 (0.774)	0.921 (1.00)	0.0153 (0.187)	0.00401 (0.0758)	0.722 (0.987)	0.558 (0.889)	0.0762 (0.427)	0.185 (0.586)
LIMA1	8 (3%)	240			0.703 (0.981)	0.384 (0.773)	0.597 (0.92)	0.524 (0.871)	0.0258 (0.252)	0.0026 (0.0559)	0.604 (0.921)	0.00011 (0.00578)
MORC3	10 (4%)	238			0.942 (1.00)	0.323 (0.733)	0.761 (1.00)	0.0567 (0.367)	0.0383 (0.307)	0.0003 (0.0113)	0.195 (0.592)	0.00537 (0.09)	0.267 (0.694)	0.0625 (0.385)
NOC3L	11 (4%)	237	0.688 (0.97)	0.204 (0.6)	0.157 (0.569)	0.383 (0.773)	0.427 (0.792)	0.726 (0.99)	0.93 (1.00)	0.00299 (0.0611)	0.852 (1.00)	0.84 (1.00)	0.56 (0.889)	0.0195 (0.211)
ARHGAP35	36 (15%)	212	0.225 (0.633)	0.887 (1.00)	0.576 (0.9)	1 (1.00)	0.186 (0.586)	0.288 (0.697)	0.227 (0.637)	0.00693 (0.108)	0.56 (0.889)	0.172 (0.578)	0.319 (0.731)	0.205 (0.601)
VPS11	11 (4%)	237	0.384 (0.773)	0.281 (0.696)	0.461 (0.819)	0.825 (1.00)	0.436 (0.799)	0.393 (0.774)	0.165 (0.577)	0.0133 (0.176)	0.291 (0.699)	0.115 (0.512)
EP300	21 (8%)	227	1 (1.00)	0.913 (1.00)	0.0153 (0.187)	0.228 (0.638)	0.109 (0.505)	0.119 (0.519)	0.451 (0.814)	0.0314 (0.283)	0.657 (0.963)	0.275 (0.696)	0.368 (0.773)	0.372 (0.773)
KLHL8	12 (5%)	236	0.381 (0.773)	0.281 (0.696)	0.147 (0.554)	0.508 (0.864)	0.713 (0.984)	0.965 (1.00)	0.233 (0.644)	0.00465 (0.0839)	0.459 (0.819)	0.911 (1.00)	0.453 (0.814)	1 (1.00)
GNPTAB	20 (8%)	228	0.453 (0.814)	0.0797 (0.427)	0.111 (0.508)	0.116 (0.515)	0.711 (0.984)	0.632 (0.946)	0.153 (0.56)	0.00053 (0.0179)	0.832 (1.00)	0.222 (0.629)	0.701 (0.981)	0.415 (0.792)
ARID5B	29 (12%)	219	0.961 (1.00)	0.139 (0.539)	0.00481 (0.0855)	0.188 (0.587)	0.13 (0.532)	0.843 (1.00)	0.164 (0.577)	0.0429 (0.318)	0.154 (0.562)	0.109 (0.503)	0.193 (0.59)	0.655 (0.963)
ZNF471	15 (6%)	233	0.683 (0.97)	0.0916 (0.457)	0.11 (0.505)	0.558 (0.889)	0.938 (1.00)	0.448 (0.81)	0.425 (0.792)	9e-05 (0.00495)	0.191 (0.589)	0.221 (0.629)	1 (1.00)	0.326 (0.736)
MORC4	20 (8%)	228	0.58 (0.905)	0.887 (1.00)	0.105 (0.492)	0.441 (0.805)	0.0345 (0.297)	0.0581 (0.372)	0.131 (0.532)	0.0841 (0.443)	0.0234 (0.235)	0.128 (0.532)	0.0329 (0.29)	0.379 (0.773)
SELP	10 (4%)	238	0.383 (0.773)	0.281 (0.696)	0.23 (0.642)	1 (1.00)	1 (1.00)	0.522 (0.87)	0.264 (0.689)	0.00735 (0.112)	0.481 (0.838)	0.123 (0.526)
RBMX	12 (5%)	236	0.193 (0.589)	0.093 (0.457)	0.176 (0.584)	0.778 (1.00)	0.56 (0.889)	0.749 (0.999)	0.611 (0.929)	0.111 (0.507)	0.812 (1.00)	0.00478 (0.0855)	0.562 (0.889)	1 (1.00)
MARK3	11 (4%)	237	0.132 (0.532)	0.0915 (0.457)	0.161 (0.576)	0.0377 (0.305)	0.517 (0.87)	0.303 (0.715)	0.549 (0.886)	0.00051 (0.0175)	0.398 (0.774)	0.313 (0.724)
ZNF263	7 (3%)	241			0.498 (0.852)	0.385 (0.773)	0.0192 (0.21)	0.708 (0.982)	0.511 (0.865)	0.0335 (0.293)	0.206 (0.601)	0.714 (0.984)	0.805 (1.00)	0.0349 (0.297)
INTS7	8 (3%)	240	0.38 (0.773)	0.281 (0.696)	0.42 (0.792)		0.321 (0.732)	0.16 (0.572)	0.0748 (0.426)	0.00498 (0.0872)	0.34 (0.754)	0.118 (0.519)
L1TD1	16 (6%)	232			0.0722 (0.417)	0.148 (0.554)	0.77 (1.00)	0.372 (0.773)	0.402 (0.774)	0.00105 (0.0299)	0.843 (1.00)	0.283 (0.696)	0.746 (0.997)	0.551 (0.889)
NAT1	7 (3%)	241	0.379 (0.773)	0.0777 (0.427)	0.433 (0.795)		0.777 (1.00)	1 (1.00)	0.405 (0.778)	0.00233 (0.0529)	1 (1.00)	0.284 (0.696)
JAKMIP2	12 (5%)	236	0.379 (0.773)	0.284 (0.696)	0.124 (0.526)	0.558 (0.889)	0.515 (0.87)	0.103 (0.487)	0.0674 (0.401)	0.00063 (0.0199)	0.0874 (0.453)	0.165 (0.577)
ING1	12 (5%)	236			0.149 (0.554)	0.713 (0.984)	0.186 (0.586)	0.673 (0.97)	0.655 (0.963)	0.0578 (0.372)	0.926 (1.00)	0.04 (0.312)	0.0156 (0.187)	0.0995 (0.475)
ZNF781	10 (4%)	238			0.268 (0.696)	0.765 (1.00)	0.367 (0.773)	0.691 (0.972)	0.526 (0.872)	0.0137 (0.178)	0.527 (0.874)	0.569 (0.893)	1 (1.00)	0.323 (0.734)
DNER	18 (7%)	230	0.19 (0.588)	0.0926 (0.457)	0.0297 (0.271)	0.658 (0.963)	0.0951 (0.462)	0.781 (1.00)	0.867 (1.00)	0.00036 (0.0131)	0.737 (0.994)	0.56 (0.889)	0.863 (1.00)	0.479 (0.837)
CDK17	14 (6%)	234	0.0451 (0.326)	0.00211 (0.0499)	0.191 (0.589)	0.0599 (0.381)	0.683 (0.97)	0.97 (1.00)	0.943 (1.00)	0.0291 (0.269)	0.424 (0.792)	0.604 (0.921)	0.719 (0.985)	0.0265 (0.254)
USP28	10 (4%)	238			0.351 (0.767)	0.188 (0.587)	0.479 (0.837)	0.475 (0.833)	0.308 (0.722)	0.00888 (0.131)	1 (1.00)	0.176 (0.584)	0.562 (0.889)	0.183 (0.586)
MSH6	17 (7%)	231	0.38 (0.773)	0.282 (0.696)	0.0718 (0.416)	0.628 (0.946)	0.946 (1.00)	0.519 (0.87)	0.34 (0.754)	0.00019 (0.00864)	0.492 (0.848)	0.139 (0.539)	0.183 (0.586)	0.686 (0.97)
C14ORF166B	9 (4%)	239			0.371 (0.773)	0.0386 (0.308)	0.568 (0.893)	0.738 (0.994)	0.912 (1.00)	0.0225 (0.231)	0.352 (0.769)	0.229 (0.64)	0.745 (0.997)	0.356 (0.773)
RAE1	11 (4%)	237	0.455 (0.814)	0.0777 (0.427)	0.461 (0.819)	0.188 (0.587)	0.0391 (0.309)	0.677 (0.97)	0.472 (0.829)	0.018 (0.206)	0.509 (0.865)	0.413 (0.791)	0.228 (0.638)	0.603 (0.92)
POLE	27 (11%)	221	0.735 (0.994)	0.0608 (0.381)	0.0383 (0.307)	0.252 (0.67)	0.96 (1.00)	0.729 (0.994)	0.904 (1.00)	0.0132 (0.176)	0.608 (0.926)	0.151 (0.556)	0.184 (0.586)	0.536 (0.876)
AHCYL1	6 (2%)	242			0.424 (0.792)	1 (1.00)	0.626 (0.946)	0.734 (0.994)	1 (1.00)	0.0121 (0.169)	0.679 (0.97)	0.743 (0.997)
ZNF334	17 (7%)	231	1 (1.00)	0.0789 (0.427)	0.304 (0.716)	0.373 (0.773)	0.563 (0.889)	0.65 (0.963)	0.398 (0.774)	0.0126 (0.171)	0.948 (1.00)	0.55 (0.888)	0.875 (1.00)	0.532 (0.876)
SLC26A8	12 (5%)	236			0.146 (0.554)	0.633 (0.947)	0.682 (0.97)	0.439 (0.802)	0.297 (0.708)	0.00064 (0.0199)	0.236 (0.651)	0.541 (0.879)	0.361 (0.773)	0.602 (0.92)
NFE2L3	12 (5%)	236			1 (1.00)	0.033 (0.29)	0.779 (1.00)	0.298 (0.708)	0.0469 (0.334)	0.0191 (0.21)	0.462 (0.819)	0.31 (0.724)	0.216 (0.621)	0.226 (0.636)
FAM65B	16 (6%)	232			0.0433 (0.318)	0.328 (0.738)	0.481 (0.838)	0.447 (0.81)	0.581 (0.905)	0.00722 (0.111)	0.943 (1.00)	0.111 (0.506)	0.602 (0.92)	0.328 (0.738)
TIGD4	13 (5%)	235	0.904 (1.00)	0.583 (0.906)	0.453 (0.814)	0.877 (1.00)	0.703 (0.981)	0.078 (0.427)	0.332 (0.741)	0.00168 (0.0418)	0.149 (0.554)	0.539 (0.878)	0.173 (0.58)	0.6 (0.92)
FILIP1	16 (6%)	232	0.535 (0.876)	0.246 (0.664)	0.301 (0.713)	0.388 (0.774)	0.74 (0.994)	0.117 (0.518)	0.807 (1.00)	0.0025 (0.0552)	0.846 (1.00)	0.119 (0.519)	0.567 (0.892)	1 (1.00)
WBP4	8 (3%)	240			0.392 (0.774)	0.107 (0.498)	1 (1.00)	0.872 (1.00)	0.364 (0.773)	0.0009 (0.0266)	0.0781 (0.427)	0.149 (0.554)	0.563 (0.889)	0.113 (0.508)
TRIM59	9 (4%)	239			0.118 (0.519)	0.86 (1.00)	0.542 (0.88)	0.907 (1.00)	0.704 (0.981)	0.0776 (0.427)	0.668 (0.97)	0.16 (0.572)	0.185 (0.586)	0.00487 (0.0859)
RSBN1L	12 (5%)	236	0.133 (0.532)	0.0924 (0.457)	0.179 (0.586)	0.555 (0.889)	0.37 (0.773)	0.216 (0.62)	0.297 (0.708)	0.0044 (0.0812)	0.369 (0.773)	0.735 (0.994)
REV3L	20 (8%)	228	0.382 (0.773)	0.28 (0.696)	0.0259 (0.252)	0.327 (0.738)	0.775 (1.00)	0.651 (0.963)	0.561 (0.889)	0.0009 (0.0266)	0.598 (0.92)	0.0663 (0.396)	0.311 (0.724)	0.282 (0.696)
CAB39L	8 (3%)	240			0.394 (0.774)		0.877 (1.00)	0.147 (0.554)	0.738 (0.994)	0.0198 (0.214)	0.602 (0.92)	0.338 (0.752)
INPP4B	12 (5%)	236	0.458 (0.818)	0.0792 (0.427)	0.275 (0.696)		0.696 (0.976)	0.391 (0.774)	1 (1.00)	0.0022 (0.0515)	0.635 (0.948)	0.861 (1.00)
C1ORF100	9 (4%)	239	0.38 (0.773)	0.28 (0.696)	0.0621 (0.385)	1 (1.00)	0.398 (0.774)	0.322 (0.733)	0.251 (0.67)	0.0146 (0.186)	0.0928 (0.457)	0.569 (0.893)
IL20	7 (3%)	241	0.135 (0.532)	0.0922 (0.457)	0.433 (0.796)		0.517 (0.87)	0.541 (0.879)	0.631 (0.946)	0.0176 (0.203)	0.284 (0.696)	0.365 (0.773)
RHBDD3	4 (2%)	244			0.771 (1.00)	0.112 (0.508)	0.396 (0.774)	0.106 (0.496)	0.223 (0.631)	0.023 (0.233)	0.685 (0.97)	0.0472 (0.334)
BRDT	14 (6%)	234	1 (1.00)	0.913 (1.00)	0.0538 (0.356)	0.634 (0.948)	0.77 (1.00)	0.236 (0.651)	0.546 (0.886)	0.00754 (0.114)	0.938 (1.00)	0.363 (0.773)	0.185 (0.586)	0.688 (0.97)
NAA15	14 (6%)	234	0.537 (0.876)	0.248 (0.666)	0.655 (0.963)	0.0984 (0.471)	0.876 (1.00)	0.482 (0.838)	0.114 (0.509)	0.00107 (0.0301)	0.184 (0.586)	0.375 (0.773)	0.192 (0.589)	0.373 (0.773)
ZNF662	13 (5%)	235	0.379 (0.773)	0.282 (0.696)	0.454 (0.814)	0.138 (0.538)	0.807 (1.00)	0.131 (0.532)	0.0635 (0.389)	6e-05 (0.00355)	0.574 (0.898)	0.257 (0.677)	0.361 (0.773)	0.0753 (0.427)
PSMC4	11 (4%)	237			0.349 (0.766)	0.444 (0.809)	0.902 (1.00)	0.522 (0.87)	0.267 (0.694)	0.00807 (0.122)	0.72 (0.986)	0.177 (0.584)	0.13 (0.532)	0.816 (1.00)
PPIL4	11 (4%)	237	0.382 (0.773)	0.285 (0.696)	0.655 (0.963)	0.657 (0.963)	1 (1.00)	0.176 (0.584)	0.132 (0.532)	0.00235 (0.0529)	0.247 (0.666)	0.0893 (0.457)	0.055 (0.36)	0.0348 (0.297)
CCDC144A	18 (7%)	230	0.809 (1.00)	0.0937 (0.46)	0.558 (0.889)	0.427 (0.792)	0.846 (1.00)	0.332 (0.741)	0.591 (0.915)	0.00395 (0.0753)	0.46 (0.819)	0.639 (0.951)	0.866 (1.00)	0.289 (0.697)
TUBGCP6	20 (8%)	228			0.0396 (0.31)	0.178 (0.585)	0.137 (0.536)	0.294 (0.704)	0.705 (0.981)	0.00087 (0.0264)	0.959 (1.00)	0.149 (0.554)	1 (1.00)	0.536 (0.876)
PER3	12 (5%)	236			0.148 (0.554)	0.133 (0.532)	0.338 (0.752)	0.211 (0.61)	0.0679 (0.401)	0.00064 (0.0199)	0.683 (0.97)	0.0819 (0.436)	0.129 (0.532)	0.167 (0.577)
ZNF674	14 (6%)	234			0.419 (0.792)	0.876 (1.00)	0.659 (0.965)	0.178 (0.585)	0.2 (0.598)	0.00207 (0.0494)	0.15 (0.554)	0.373 (0.773)	0.185 (0.586)	0.688 (0.97)
ZNF606	16 (6%)	232	0.133 (0.532)	0.0915 (0.457)	0.0716 (0.416)	0.19 (0.588)	0.737 (0.994)	0.719 (0.985)	0.809 (1.00)	0.00239 (0.0533)	0.844 (1.00)	0.488 (0.845)	1 (1.00)	0.601 (0.92)
LETMD1	6 (2%)	242	0.38 (0.773)	0.284 (0.696)	0.74 (0.994)		1 (1.00)	0.732 (0.994)	0.126 (0.529)	0.00391 (0.0753)	0.0643 (0.391)	0.134 (0.532)
ZNF721	13 (5%)	235	1 (1.00)	0.0774 (0.427)	0.135 (0.532)	0.629 (0.946)	0.467 (0.824)	0.202 (0.6)	0.52 (0.87)	0.00526 (0.09)	0.462 (0.819)	0.286 (0.697)	0.188 (0.587)	1 (1.00)
AGXT2	11 (4%)	237	0.629 (0.946)	0.81 (1.00)	0.159 (0.572)	0.732 (0.994)	0.78 (1.00)	0.652 (0.963)	0.17 (0.577)	0.00682 (0.107)	0.324 (0.734)	0.571 (0.895)	0.564 (0.889)	0.357 (0.773)
DYM	10 (4%)	238			0.271 (0.696)	0.282 (0.696)	0.912 (1.00)	0.158 (0.569)	0.722 (0.987)	0.00379 (0.074)	1 (1.00)	0.101 (0.48)	0.807 (1.00)	0.167 (0.577)
TAB3	18 (7%)	230	0.133 (0.532)	0.0943 (0.46)	0.0454 (0.326)	0.277 (0.696)	0.703 (0.981)	0.736 (0.994)	0.0499 (0.341)	4e-05 (0.00263)	0.457 (0.818)	0.39 (0.774)	0.0718 (0.416)	0.492 (0.848)
ZNF649	14 (6%)	234	0.535 (0.876)	0.245 (0.664)	0.0887 (0.457)	1 (1.00)	0.693 (0.974)	0.956 (1.00)	0.942 (1.00)	0.014 (0.181)	0.141 (0.543)	0.778 (1.00)	0.36 (0.773)	0.6 (0.92)
KIF21A	15 (6%)	233	0.685 (0.97)	0.206 (0.601)	0.0887 (0.457)	0.0526 (0.354)	0.836 (1.00)	0.586 (0.909)	0.425 (0.792)	0.00097 (0.0283)	0.452 (0.814)	0.0693 (0.408)	1 (1.00)	0.687 (0.97)
EXOSC9	10 (4%)	238	0.687 (0.97)	0.203 (0.6)	0.35 (0.767)	0.113 (0.508)	1 (1.00)	0.746 (0.997)	0.522 (0.87)	0.00119 (0.0323)	0.763 (1.00)	0.725 (0.99)
ZKSCAN1	7 (3%)	241			0.498 (0.852)	0.445 (0.809)	0.107 (0.498)	0.162 (0.576)	0.405 (0.778)	0.0235 (0.235)	0.715 (0.984)	0.277 (0.696)	0.805 (1.00)	0.812 (1.00)
OR8B8	7 (3%)	241			0.189 (0.587)	0.78 (1.00)	0.247 (0.666)	0.425 (0.792)	0.308 (0.722)	0.00537 (0.09)	0.386 (0.774)	0.427 (0.792)
NRIP1	13 (5%)	235	0.383 (0.773)	0.0785 (0.427)	0.45 (0.813)	0.717 (0.984)	0.934 (1.00)	0.222 (0.629)	0.33 (0.74)	0.00059 (0.0191)	0.15 (0.554)	0.133 (0.532)	0.358 (0.773)	0.599 (0.92)
CCDC146	14 (6%)	234	0.906 (1.00)	0.0479 (0.334)	0.12 (0.52)	0.634 (0.948)	0.491 (0.848)	0.362 (0.773)	0.547 (0.886)	0.00082 (0.0252)	0.299 (0.71)	0.375 (0.773)	0.175 (0.582)	0.326 (0.736)
PTPN12	10 (4%)	238	0.0558 (0.361)	0.151 (0.556)	0.166 (0.577)	0.778 (1.00)	0.0682 (0.402)	0.899 (1.00)	0.306 (0.72)	0.0134 (0.176)	1 (1.00)	0.621 (0.941)
RIOK3	9 (4%)	239			0.194 (0.591)	0.51 (0.865)	1 (1.00)	0.908 (1.00)	0.403 (0.776)	0.0154 (0.187)	1 (1.00)	0.696 (0.976)	0.495 (0.85)	0.689 (0.97)
CASP8	17 (7%)	231	0.381 (0.773)	0.0781 (0.427)	0.262 (0.686)	0.254 (0.674)	0.9 (1.00)	0.682 (0.97)	0.601 (0.92)	0.00395 (0.0753)	0.314 (0.726)	0.745 (0.997)	1 (1.00)	0.633 (0.946)
DENND3	15 (6%)	233	0.379 (0.773)	0.28 (0.696)	0.0894 (0.457)	0.199 (0.597)	0.516 (0.87)	0.238 (0.652)	0.0481 (0.334)	1e-05 (0.000815)	0.276 (0.696)	0.244 (0.662)	0.13 (0.532)	0.168 (0.577)
CHEK2	12 (5%)	236	0.685 (0.97)	0.206 (0.601)	0.416 (0.792)	0.282 (0.696)	0.761 (1.00)	0.141 (0.543)	0.166 (0.577)	0.0005 (0.0174)	0.392 (0.774)	0.653 (0.963)	0.806 (1.00)	0.294 (0.704)
ZMYM2	17 (7%)	231	0.382 (0.773)	0.0782 (0.427)	0.303 (0.715)	1 (1.00)	0.877 (1.00)	0.254 (0.674)	0.263 (0.688)	0.0184 (0.21)	0.65 (0.963)	0.321 (0.732)	0.12 (0.521)	0.096 (0.465)
EFCAB4B	11 (4%)	237			0.457 (0.818)	0.877 (1.00)	0.0166 (0.194)	0.583 (0.906)	0.687 (0.97)	0.0544 (0.357)	0.635 (0.948)	0.363 (0.773)	0.185 (0.586)	0.0356 (0.297)
PPIG	16 (6%)	232	0.194 (0.591)	0.0918 (0.457)	0.0415 (0.316)	1 (1.00)	0.892 (1.00)	0.979 (1.00)	0.146 (0.554)	0.00195 (0.047)	0.0919 (0.457)	0.244 (0.662)	0.232 (0.644)	0.0531 (0.354)
TPX2	6 (2%)	242			0.425 (0.792)	0.823 (1.00)	0.0511 (0.347)	0.197 (0.593)	0.0854 (0.445)	0.158 (0.569)	0.0187 (0.21)	0.136 (0.533)	0.0416 (0.316)	0.181 (0.586)
PARG	9 (4%)	239			0.115 (0.512)	0.878 (1.00)	1 (1.00)	0.61 (0.928)	0.199 (0.597)	0.00833 (0.124)	0.158 (0.569)	0.0795 (0.427)	0.041 (0.316)	0.169 (0.577)
PSMD3	11 (4%)	237	0.687 (0.97)	0.206 (0.601)	0.35 (0.767)	0.518 (0.87)	0.479 (0.837)	0.391 (0.774)	0.47 (0.826)	0.0175 (0.203)	0.74 (0.994)	0.973 (1.00)	0.13 (0.532)	0.814 (1.00)
STRN3	12 (5%)	236			0.622 (0.942)	0.716 (0.984)	0.704 (0.981)	0.736 (0.994)	0.133 (0.532)	0.0509 (0.347)	0.0227 (0.231)	0.0886 (0.457)	0.119 (0.519)	0.095 (0.462)
MSN	15 (6%)	233	0.806 (1.00)	0.213 (0.614)	0.937 (1.00)	0.0237 (0.235)	0.42 (0.792)	0.164 (0.577)	0.0436 (0.318)	0.0281 (0.264)	0.185 (0.586)	0.163 (0.577)	0.0407 (0.315)	0.0636 (0.389)
RBL2	12 (5%)	236	0.535 (0.876)	0.249 (0.666)	0.15 (0.554)	0.86 (1.00)	0.433 (0.795)	0.732 (0.994)	0.351 (0.767)	0.00195 (0.047)	0.147 (0.554)	0.286 (0.697)	0.498 (0.852)	1 (1.00)
PDGFRA	12 (5%)	236			0.124 (0.526)	0.189 (0.587)	1 (1.00)	0.553 (0.889)	0.466 (0.824)	0.00037 (0.0133)	0.243 (0.662)	0.733 (0.994)	0.392 (0.774)	0.356 (0.773)
CCDC82	12 (5%)	236	0.38 (0.773)	0.284 (0.696)	0.622 (0.942)	0.656 (0.963)	0.493 (0.848)	0.182 (0.586)	0.132 (0.532)	0.00297 (0.0611)	0.685 (0.97)	0.0353 (0.297)	0.519 (0.87)	0.0444 (0.323)
ASXL2	14 (6%)	234	0.382 (0.773)	0.283 (0.696)	0.418 (0.792)	0.388 (0.774)	0.188 (0.587)	0.666 (0.97)	0.275 (0.696)	0.00904 (0.133)	0.824 (1.00)	0.362 (0.773)	0.516 (0.87)	0.0277 (0.262)
THAP5	6 (2%)	242			0.158 (0.569)	0.0369 (0.302)	0.86 (1.00)	0.733 (0.994)	0.29 (0.697)	0.00536 (0.09)	1 (1.00)	0.869 (1.00)
ZCCHC18	6 (2%)	242			0.536 (0.876)	0.113 (0.508)	0.595 (0.919)	0.107 (0.498)	0.126 (0.529)	0.00517 (0.0892)	0.525 (0.872)	0.0846 (0.444)
PRKCE	9 (4%)	239			0.192 (0.589)	0.879 (1.00)	1 (1.00)	0.522 (0.87)	0.2 (0.598)	0.0151 (0.187)	0.762 (1.00)	0.135 (0.532)	0.124 (0.527)	1 (1.00)
BMP2K	13 (5%)	235	0.135 (0.532)	0.0911 (0.457)	0.165 (0.577)	0.262 (0.686)	0.631 (0.946)	0.912 (1.00)	0.271 (0.696)	0.0151 (0.187)	0.212 (0.614)	0.344 (0.759)	1 (1.00)	0.766 (1.00)
PRPF38B	11 (4%)	237			0.274 (0.696)	0.106 (0.496)	0.684 (0.97)	1 (1.00)	0.169 (0.577)	0.00042 (0.0148)	0.224 (0.633)	0.214 (0.617)	0.393 (0.774)	0.112 (0.508)
LGMN	7 (3%)	241	0.383 (0.773)	0.0793 (0.427)	0.43 (0.795)		0.712 (0.984)	1 (1.00)	0.146 (0.554)	0.00116 (0.0319)	1 (1.00)	0.134 (0.532)
EMR1	11 (4%)	237			0.178 (0.585)	0.279 (0.696)	0.261 (0.686)	0.536 (0.876)	0.37 (0.773)	0.00113 (0.0314)	0.798 (1.00)	0.166 (0.577)	0.185 (0.586)	0.0355 (0.297)
OR5AK2	5 (2%)	243			0.125 (0.529)		1 (1.00)	0.319 (0.731)	0.285 (0.696)	0.0199 (0.214)	0.129 (0.532)	0.53 (0.876)
ZNF534	9 (4%)	239			0.192 (0.589)	0.0377 (0.305)	0.566 (0.892)	1 (1.00)	0.249 (0.666)	0.00028 (0.011)	0.82 (1.00)	0.515 (0.87)
FAM122A	6 (2%)	242			0.534 (0.876)		1 (1.00)	0.175 (0.582)	0.224 (0.633)	0.0051 (0.0886)	0.632 (0.946)	0.0853 (0.445)
PIK3CA	131 (53%)	117	0.891 (1.00)	0.372 (0.773)	0.6 (0.92)	0.747 (0.998)	0.204 (0.6)	0.39 (0.774)	0.733 (0.994)	0.552 (0.889)	0.221 (0.629)	0.428 (0.793)	0.347 (0.764)	0.637 (0.949)
SPOP	21 (8%)	227	0.349 (0.766)	0.674 (0.97)	0.574 (0.898)	0.421 (0.792)	0.905 (1.00)	0.42 (0.792)	0.426 (0.792)	0.108 (0.5)	0.847 (1.00)	0.367 (0.773)	0.0831 (0.44)	0.418 (0.792)
FGFR2	31 (12%)	217	0.385 (0.773)	0.364 (0.773)	0.269 (0.696)	1 (1.00)	0.445 (0.809)	0.717 (0.984)	1 (1.00)	0.075 (0.426)	0.805 (1.00)	0.105 (0.492)	0.291 (0.699)	1 (1.00)
MAX	9 (4%)	239			0.37 (0.773)	0.581 (0.905)	0.601 (0.92)	0.721 (0.986)	0.774 (1.00)	0.289 (0.697)	0.524 (0.871)	0.966 (1.00)	0.186 (0.586)	0.813 (1.00)
SOX17	7 (3%)	241			0.0494 (0.339)	0.14 (0.542)	0.877 (1.00)	1 (1.00)	0.202 (0.6)	0.488 (0.845)	0.798 (1.00)	0.482 (0.838)
CCND1	14 (6%)	234	0.63 (0.946)	0.808 (1.00)	0.13 (0.532)	0.262 (0.686)	0.847 (1.00)	0.793 (1.00)	0.482 (0.838)	0.0476 (0.334)	0.0805 (0.431)	0.594 (0.919)	0.495 (0.85)	0.38 (0.773)
NRAS	9 (4%)	239			0.75 (1)		0.774 (1.00)	0.049 (0.338)	0.641 (0.953)	0.865 (1.00)	1 (1.00)	0.906 (1.00)
ALG8	11 (4%)	237	1 (1.00)	0.205 (0.601)	0.655 (0.963)	0.189 (0.587)	0.048 (0.334)	0.396 (0.774)	1 (1.00)	0.172 (0.578)	0.797 (1.00)	0.717 (0.984)	0.393 (0.774)	1 (1.00)
SOS1	12 (5%)	236	0.631 (0.946)	0.808 (1.00)	0.0748 (0.426)	0.556 (0.889)	0.245 (0.664)	0.169 (0.577)	0.863 (1.00)	0.039 (0.309)	0.224 (0.633)	0.654 (0.963)	0.13 (0.532)	0.168 (0.577)
CCDC6	6 (2%)	242			0.865 (1.00)	0.518 (0.87)	0.777 (1.00)	0.476 (0.834)	0.453 (0.814)	0.243 (0.662)	0.079 (0.427)	0.568 (0.893)	0.564 (0.889)	0.447 (0.81)
EIF2S2	9 (4%)	239			0.355 (0.773)	0.735 (0.994)	0.196 (0.593)	0.158 (0.569)	0.252 (0.67)	0.372 (0.773)	0.763 (1.00)	0.516 (0.87)	0.806 (1.00)	0.814 (1.00)
RASA1	21 (8%)	227	0.384 (0.773)	0.366 (0.773)	0.113 (0.508)	0.657 (0.963)	0.301 (0.713)	0.833 (1.00)	0.582 (0.905)	0.0624 (0.385)	0.468 (0.824)	0.531 (0.876)	0.401 (0.774)	0.168 (0.577)
C9ORF23	9 (4%)	239			0.396 (0.774)	0.0608 (0.381)	0.476 (0.834)	0.636 (0.948)	1 (1.00)	0.0779 (0.427)	0.437 (0.799)	0.0828 (0.439)	0.192 (0.589)	0.883 (1.00)
WDR45	11 (4%)	237			0.653 (0.963)	0.58 (0.905)	1 (1.00)	0.585 (0.908)	0.863 (1.00)	0.242 (0.661)	0.226 (0.635)	0.204 (0.6)	0.186 (0.586)	0.296 (0.707)
ZNF485	9 (4%)	239	1 (1.00)	0.078 (0.427)	0.359 (0.773)	1 (1.00)	1 (1.00)	0.313 (0.724)	0.642 (0.953)	0.414 (0.792)	0.127 (0.532)	0.294 (0.704)
MSH4	15 (6%)	233	0.682 (0.97)	0.0925 (0.457)	0.091 (0.457)	0.879 (1.00)	0.482 (0.838)	0.952 (1.00)	0.845 (1.00)	0.0288 (0.268)	0.422 (0.792)	0.0847 (0.444)	0.187 (0.587)	0.689 (0.97)
RRAS2	4 (2%)	244			0.0982 (0.471)		0.843 (1.00)	0.203 (0.6)	0.172 (0.578)	0.213 (0.614)	0.391 (0.774)	0.918 (1.00)
CTNND1	19 (8%)	229	0.287 (0.697)	0.399 (0.774)	0.136 (0.533)	1 (1.00)	0.95 (1.00)	0.174 (0.582)	0.601 (0.92)	0.0404 (0.313)	0.911 (1.00)	0.236 (0.65)	0.232 (0.644)	0.534 (0.876)
MRPL47	6 (2%)	242	0.687 (0.97)	0.532 (0.876)	1 (1.00)	0.776 (1.00)	1 (1.00)	0.505 (0.86)	0.527 (0.874)	0.0735 (0.422)	1 (1.00)	0.702 (0.981)
SLC1A3	12 (5%)	236			0.665 (0.969)	0.668 (0.97)	0.779 (1.00)	0.398 (0.774)	0.154 (0.562)	0.0306 (0.278)	0.312 (0.724)	0.289 (0.697)	0.306 (0.72)	0.423 (0.792)
SERHL2	6 (2%)	242			0.536 (0.876)	1 (1.00)	0.379 (0.773)	0.937 (1.00)	1 (1.00)	0.342 (0.756)	0.74 (0.994)	0.716 (0.984)	0.806 (1.00)	1 (1.00)
OR52I2	8 (3%)	240	0.686 (0.97)	0.534 (0.876)	0.704 (0.981)	0.0371 (0.303)	0.0652 (0.394)	0.776 (1.00)	0.155 (0.565)	0.0982 (0.471)	0.714 (0.984)	0.665 (0.969)	1 (1.00)	1 (1.00)
SGK1	13 (5%)	235	0.38 (0.773)	0.283 (0.696)	0.315 (0.726)	0.385 (0.773)	0.513 (0.868)	1 (1.00)	0.218 (0.623)	0.347 (0.764)	0.426 (0.792)	0.0702 (0.412)
ERBB3	17 (7%)	231			0.174 (0.581)	0.489 (0.845)	0.0656 (0.394)	0.0379 (0.306)	0.211 (0.612)	0.27 (0.696)	0.952 (1.00)	0.821 (1.00)	0.664 (0.969)	0.555 (0.889)
SLC44A3	6 (2%)	242			0.427 (0.792)	0.684 (0.97)	1 (1.00)	0.939 (1.00)	1 (1.00)	0.252 (0.67)	0.679 (0.97)	0.275 (0.696)
SLC34A3	6 (2%)	242			0.425 (0.792)	0.444 (0.809)	0.133 (0.532)	0.402 (0.774)	0.454 (0.814)	0.0417 (0.316)	0.387 (0.774)	0.275 (0.696)	0.358 (0.773)	0.0759 (0.427)
MLH3	17 (7%)	231	0.906 (1.00)	0.0483 (0.334)	0.0617 (0.385)	1 (1.00)	0.753 (1.00)	0.56 (0.889)	0.905 (1.00)	0.0522 (0.353)	0.686 (0.97)	0.748 (0.998)	0.752 (1.00)	1 (1.00)
CCDC160	11 (4%)	237	0.688 (0.97)	0.207 (0.602)	0.274 (0.696)	1 (1.00)	0.277 (0.696)	0.602 (0.92)	0.549 (0.886)	0.0263 (0.254)	0.919 (1.00)	0.164 (0.577)	0.56 (0.889)	0.355 (0.773)
TTC39C	7 (3%)	241	0.687 (0.97)	0.206 (0.602)	0.432 (0.795)		0.711 (0.984)	0.232 (0.644)	0.408 (0.782)	0.0265 (0.254)	0.289 (0.697)	0.331 (0.741)
GPRASP1	21 (8%)	227	0.289 (0.697)	0.0452 (0.326)	0.113 (0.508)	0.628 (0.946)	0.712 (0.984)	0.43 (0.795)	1 (1.00)	0.113 (0.508)	0.468 (0.824)	0.426 (0.792)	0.748 (0.998)	1 (1.00)
PPM1D	11 (4%)	237	0.379 (0.773)	0.281 (0.696)	0.273 (0.696)	0.151 (0.556)	0.687 (0.97)	0.749 (0.999)	0.369 (0.773)	0.0422 (0.316)	0.718 (0.985)	0.029 (0.269)	0.626 (0.946)	0.813 (1.00)
LIMK2	12 (5%)	236	0.201 (0.6)	0.452 (0.814)	0.62 (0.94)	0.377 (0.773)	0.259 (0.683)	0.216 (0.62)	0.568 (0.893)	0.307 (0.722)	0.491 (0.848)	0.393 (0.774)	1 (1.00)	0.514 (0.87)
SFRP4	8 (3%)	240	0.378 (0.773)	0.281 (0.696)	0.2 (0.598)	0.46 (0.819)	0.677 (0.97)	0.0947 (0.462)	0.181 (0.586)	0.0603 (0.381)	0.122 (0.522)	0.952 (1.00)
TXNRD1	8 (3%)	240	0.688 (0.97)	0.204 (0.6)	0.701 (0.981)	0.384 (0.773)	0.489 (0.845)	0.302 (0.714)	0.363 (0.773)	0.0361 (0.298)	0.0556 (0.361)	0.17 (0.577)
RASSF9	9 (4%)	239			0.393 (0.774)	0.776 (1.00)	0.399 (0.774)	0.708 (0.982)	0.64 (0.952)	0.0479 (0.334)	0.544 (0.882)	0.924 (1.00)
MECOM	12 (5%)	236	0.535 (0.876)	0.0471 (0.334)	0.148 (0.554)	0.557 (0.889)	0.745 (0.997)	0.396 (0.774)	0.436 (0.799)	0.257 (0.678)	0.313 (0.724)	0.657 (0.963)	1 (1.00)	1 (1.00)
ATP6V1C2	12 (5%)	236			0.197 (0.593)	0.51 (0.865)	0.716 (0.984)	0.405 (0.778)	0.612 (0.93)	0.0435 (0.318)	0.426 (0.792)	0.483 (0.838)	1 (1.00)	0.135 (0.532)
CCDC150	11 (4%)	237			0.27 (0.696)	0.387 (0.774)	0.432 (0.795)	0.054 (0.357)	0.863 (1.00)	0.064 (0.391)	0.783 (1.00)	0.538 (0.876)	1 (1.00)	0.493 (0.848)
BHLHB9	8 (3%)	240			0.396 (0.774)	1 (1.00)	0.794 (1.00)	0.247 (0.666)	0.122 (0.524)	0.0359 (0.298)	0.28 (0.696)	0.156 (0.568)
WDR65	6 (2%)	242			0.427 (0.792)	0.732 (0.994)	0.874 (1.00)	0.609 (0.926)	0.45 (0.813)	0.0892 (0.457)	0.162 (0.576)	0.673 (0.97)	0.562 (0.889)	0.357 (0.773)
ZNF620	9 (4%)	239			0.753 (1.00)	1 (1.00)	0.393 (0.774)	0.422 (0.792)	0.401 (0.774)	0.0625 (0.385)	0.601 (0.92)	0.0578 (0.372)	0.13 (0.532)	0.169 (0.577)
OMA1	10 (4%)	238			0.194 (0.591)	0.507 (0.863)	0.0982 (0.471)	1 (1.00)	1 (1.00)	0.0532 (0.354)	0.435 (0.798)	0.283 (0.696)	0.497 (0.852)	0.297 (0.708)
EPC2	5 (2%)	243			0.504 (0.86)	1 (1.00)	0.776 (1.00)	1 (1.00)	0.248 (0.666)	0.184 (0.586)	0.274 (0.696)	0.242 (0.662)	0.561 (0.889)	0.468 (0.824)
DEPDC1B	11 (4%)	237	0.688 (0.97)	0.204 (0.6)	0.179 (0.586)	0.667 (0.97)	0.431 (0.795)	0.359 (0.773)	0.289 (0.697)	0.102 (0.483)	0.92 (1.00)	0.145 (0.554)	0.12 (0.521)	0.445 (0.809)
C3AR1	7 (3%)	241	0.38 (0.773)	0.281 (0.696)	0.498 (0.852)		0.594 (0.919)	0.939 (1.00)	0.703 (0.981)	0.168 (0.577)	0.88 (1.00)	0.601 (0.92)
STK3	10 (4%)	238			0.0602 (0.381)	0.795 (1.00)	0.739 (0.994)	0.588 (0.911)	0.395 (0.774)	0.0273 (0.26)	0.556 (0.889)	0.0867 (0.451)	0.0715 (0.416)	0.492 (0.848)
EPS8	12 (5%)	236			0.654 (0.963)	0.32 (0.731)	0.716 (0.984)	0.9 (1.00)	0.467 (0.824)	0.17 (0.577)	0.462 (0.819)	0.875 (1.00)	0.309 (0.723)	0.372 (0.773)
ZNF385B	7 (3%)	241			0.432 (0.795)	0.73 (0.994)	0.896 (1.00)	0.506 (0.862)	0.311 (0.724)	0.0263 (0.254)	0.678 (0.97)	0.331 (0.741)
NPRL2	5 (2%)	243			0.686 (0.97)		0.46 (0.819)	0.161 (0.575)	1 (1.00)	0.535 (0.876)	0.326 (0.736)	0.401 (0.774)
ATF6	14 (6%)	234	0.229 (0.64)	0.192 (0.589)	0.118 (0.519)	0.878 (1.00)	0.869 (1.00)	0.365 (0.773)	0.942 (1.00)	0.15 (0.554)	0.185 (0.586)	0.119 (0.519)	0.039 (0.309)	0.171 (0.578)
ZNF774	10 (4%)	238			0.67 (0.97)	0.667 (0.97)	0.426 (0.792)	0.707 (0.982)	0.52 (0.87)	0.134 (0.532)	0.401 (0.774)	0.314 (0.724)	0.518 (0.87)	0.172 (0.578)
MUTED	7 (3%)	241			0.43 (0.795)	0.629 (0.946)	0.332 (0.741)	0.374 (0.773)	0.708 (0.982)	0.117 (0.518)	0.446 (0.81)	0.424 (0.792)
MAPK8	11 (4%)	237	0.401 (0.774)	0.401 (0.774)	0.46 (0.819)	0.552 (0.889)	0.903 (1.00)	0.615 (0.934)	0.929 (1.00)	0.0433 (0.318)	0.92 (1.00)	0.18 (0.586)	0.267 (0.694)	0.167 (0.577)
TMEM62	9 (4%)	239			0.373 (0.773)	0.779 (1.00)	0.207 (0.602)	1 (1.00)	0.139 (0.539)	0.0462 (0.33)	0.667 (0.97)	0.239 (0.654)
RG9MTD3	8 (3%)	240			1 (1.00)	0.557 (0.889)	0.819 (1.00)	0.301 (0.714)	0.447 (0.81)	0.0367 (0.301)	0.737 (0.994)	0.171 (0.578)	0.239 (0.654)	0.182 (0.586)
KANK4	11 (4%)	237			0.0606 (0.381)	0.388 (0.774)	0.716 (0.984)	0.397 (0.774)	0.288 (0.697)	0.133 (0.532)	0.92 (1.00)	0.177 (0.584)	1 (1.00)	0.554 (0.889)
MYOM1	23 (9%)	225	0.479 (0.837)	0.094 (0.46)	0.57 (0.894)	0.352 (0.769)	0.233 (0.644)	0.485 (0.842)	0.0734 (0.422)	0.102 (0.482)	0.523 (0.871)	0.0281 (0.264)	0.0622 (0.385)	0.114 (0.509)
B3GALT5	4 (2%)	244			0.771 (1.00)		0.271 (0.696)	0.121 (0.521)	0.548 (0.886)	0.421 (0.792)	1 (1.00)	0.632 (0.946)
NSUN4	6 (2%)	242	0.277 (0.696)	0.0531 (0.354)	0.248 (0.666)	0.779 (1.00)	0.742 (0.996)	1 (1.00)	0.29 (0.697)	0.0814 (0.434)	0.63 (0.946)	0.602 (0.92)
CHD4	35 (14%)	213	0.0978 (0.471)	0.338 (0.752)	1 (1.00)	0.744 (0.997)	0.848 (1.00)	0.629 (0.946)	0.363 (0.773)	0.333 (0.743)	0.548 (0.886)	0.862 (1.00)	0.801 (1.00)	0.73 (0.994)
FCN1	7 (3%)	241			0.432 (0.795)	0.557 (0.889)	1 (1.00)	0.793 (1.00)	0.311 (0.724)	0.396 (0.774)	0.891 (1.00)	0.952 (1.00)
NIPA2	8 (3%)	240			0.417 (0.792)	0.827 (1.00)	0.283 (0.696)	0.147 (0.554)	1 (1.00)	0.0404 (0.313)	0.904 (1.00)	0.888 (1.00)	0.391 (0.774)	0.468 (0.824)
C14ORF118	13 (5%)	235	0.684 (0.97)	0.091 (0.457)	0.11 (0.505)	1 (1.00)	0.684 (0.97)	0.252 (0.67)	0.879 (1.00)	0.0851 (0.445)	0.188 (0.587)	0.542 (0.88)	0.31 (0.724)	0.883 (1.00)
SSH2	12 (5%)	236	0.682 (0.97)	0.0915 (0.457)	0.145 (0.554)	0.825 (1.00)	0.24 (0.657)	0.318 (0.731)	0.932 (1.00)	0.344 (0.759)	1 (1.00)	0.717 (0.984)	0.804 (1.00)	0.814 (1.00)
C1ORF101	12 (5%)	236	0.63 (0.946)	0.322 (0.733)	0.145 (0.554)	0.824 (1.00)	1 (1.00)	1 (1.00)	0.497 (0.852)	0.705 (0.982)	0.244 (0.662)	0.972 (1.00)	0.0419 (0.316)	0.183 (0.586)

'PTEN MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.00442 (Fisher's exact test), Q value = 0.081

Table S1. Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
PTEN MUTATED	11	6	9	7
PTEN WILD-TYPE	1	12	2	3

Figure S1. Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'PTEN MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 2e-05 (Fisher's exact test), Q value = 0.0014

Table S2. Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
PTEN MUTATED	8	0	6	7	12
PTEN WILD-TYPE	4	10	1	0	3

Figure S2. Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S3. Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PTEN MUTATED	4	126	6	3	17
PTEN WILD-TYPE	52	26	5	2	1

Figure S3. Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PTEN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S4. Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PTEN MUTATED	6	29	46
PTEN WILD-TYPE	37	10	7

Figure S4. Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'PTEN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 2e-05 (Fisher's exact test), Q value = 0.0014

Table S5. Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PTEN MUTATED	56	54	22
PTEN WILD-TYPE	15	18	38

Figure S5. Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'PTEN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S6. Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PTEN MUTATED	59	34	22	17
PTEN WILD-TYPE	9	44	9	9

Figure S6. Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S7. Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PTEN MUTATED	17	68	75
PTEN WILD-TYPE	62	17	8

Figure S7. Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'PTEN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S8. Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PTEN MUTATED	3	33	5	28	21	29	41
PTEN WILD-TYPE	41	8	12	5	14	2	5

Figure S8. Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S9. Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PTEN MUTATED	20	56	82
PTEN WILD-TYPE	49	23	10

Figure S9. Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'PTEN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S10. Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PTEN MUTATED	49	31	72	6
PTEN WILD-TYPE	24	12	7	39

Figure S10. Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S11. Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
PTEN MUTATED	7	8	52
PTEN WILD-TYPE	22	11	12

Figure S11. Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S12. Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
PTEN MUTATED	10	43	14
PTEN WILD-TYPE	23	5	17

Figure S12. Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PIK3R1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0663 (Fisher's exact test), Q value = 0.4

Table S13. Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
PIK3R1 MUTATED	5	2	6	3
PIK3R1 WILD-TYPE	7	16	5	7

'PIK3R1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0596 (Fisher's exact test), Q value = 0.38

Table S14. Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
PIK3R1 MUTATED	3	0	4	3	6
PIK3R1 WILD-TYPE	9	10	3	4	9

'PIK3R1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00034 (Fisher's exact test), Q value = 0.013

Table S15. Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PIK3R1 MUTATED	6	61	4	2	8
PIK3R1 WILD-TYPE	50	91	7	3	10

Figure S13. Get High-res Image Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PIK3R1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 3e-05 (Fisher's exact test), Q value = 0.002

Table S16. Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PIK3R1 MUTATED	5	11	29
PIK3R1 WILD-TYPE	38	28	24

Figure S14. Get High-res Image Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'PIK3R1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.00555 (Fisher's exact test), Q value = 0.092

Table S17. Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PIK3R1 MUTATED	30	29	11
PIK3R1 WILD-TYPE	41	43	49

Figure S15. Get High-res Image Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'PIK3R1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.117 (Fisher's exact test), Q value = 0.52

Table S18. Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PIK3R1 MUTATED	31	23	10	6
PIK3R1 WILD-TYPE	37	55	21	20

'PIK3R1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00017 (Fisher's exact test), Q value = 0.008

Table S19. Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PIK3R1 MUTATED	12	36	34
PIK3R1 WILD-TYPE	67	49	49

Figure S16. Get High-res Image Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'PIK3R1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00022 (Fisher's exact test), Q value = 0.0096

Table S20. Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PIK3R1 MUTATED	3	16	3	15	11	14	20
PIK3R1 WILD-TYPE	41	25	14	18	24	17	26

Figure S17. Get High-res Image Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0396 (Fisher's exact test), Q value = 0.31

Table S21. Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PIK3R1 MUTATED	15	28	37
PIK3R1 WILD-TYPE	54	51	55

Figure S18. Get High-res Image Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0296 (Fisher's exact test), Q value = 0.27

Table S22. Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PIK3R1 MUTATED	26	15	32	7
PIK3R1 WILD-TYPE	47	28	47	38

Figure S19. Get High-res Image Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.032 (Fisher's exact test), Q value = 0.29

Table S23. Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
PIK3R1 MUTATED	4	5	26
PIK3R1 WILD-TYPE	25	14	38

Figure S20. Get High-res Image Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.132 (Fisher's exact test), Q value = 0.53

Table S24. Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
PIK3R1 MUTATED	6	19	10
PIK3R1 WILD-TYPE	27	29	21

'TP53 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 2e-05 (Fisher's exact test), Q value = 0.0014

Table S25. Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
TP53 MUTATED	2	13	1	0
TP53 WILD-TYPE	10	5	10	10

Figure S21. Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'TP53 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S26. Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
TP53 MUTATED	4	10	1	1	0
TP53 WILD-TYPE	8	0	6	6	15

Figure S22. Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S27. Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
TP53 MUTATED	52	10	3	0	3
TP53 WILD-TYPE	4	142	8	5	15

Figure S23. Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S28. Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
TP53 MUTATED	32	3	5
TP53 WILD-TYPE	11	36	48

Figure S24. Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'TP53 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 2e-05 (Fisher's exact test), Q value = 0.0014

Table S29. Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
TP53 MUTATED	12	15	31
TP53 WILD-TYPE	59	57	29

Figure S25. Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'TP53 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S30. Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
TP53 MUTATED	4	39	9	6
TP53 WILD-TYPE	64	39	22	20

Figure S26. Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S31. Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
TP53 MUTATED	58	7	4
TP53 WILD-TYPE	21	78	79

Figure S27. Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S32. Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
TP53 MUTATED	38	0	11	4	12	3	1
TP53 WILD-TYPE	6	41	6	29	23	28	45

Figure S28. Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S33. Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
TP53 MUTATED	46	11	7
TP53 WILD-TYPE	23	68	85

Figure S29. Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S34. Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
TP53 MUTATED	24	1	4	35
TP53 WILD-TYPE	49	42	75	10

Figure S30. Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S35. Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
TP53 MUTATED	21	6	9
TP53 WILD-TYPE	8	13	55

Figure S31. Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S36. Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
TP53 MUTATED	23	3	10
TP53 WILD-TYPE	10	45	21

Figure S32. Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CTCF MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 0.55

Table S37. Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
CTCF MUTATED	3	1	4	1
CTCF WILD-TYPE	9	17	7	9

'CTCF MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.203 (Fisher's exact test), Q value = 0.6

Table S38. Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
CTCF MUTATED	3	0	3	1	2
CTCF WILD-TYPE	9	10	4	6	13

'CTCF MUTATION STATUS' versus 'CN_CNMF'

P value = 5e-05 (Fisher's exact test), Q value = 0.0031

Table S39. Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CTCF MUTATED	0	38	0	0	3
CTCF WILD-TYPE	56	114	11	5	15

Figure S33. Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CTCF MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0657 (Fisher's exact test), Q value = 0.39

Table S40. Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CTCF MUTATED	3	10	8
CTCF WILD-TYPE	40	29	45

'CTCF MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.00684 (Fisher's exact test), Q value = 0.11

Table S41. Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CTCF MUTATED	14	17	3
CTCF WILD-TYPE	57	55	57

Figure S34. Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'CTCF MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0227 (Fisher's exact test), Q value = 0.23

Table S42. Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CTCF MUTATED	19	8	5	2
CTCF WILD-TYPE	49	70	26	24

Figure S35. Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'CTCF MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00029 (Fisher's exact test), Q value = 0.011

Table S43. Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CTCF MUTATED	4	17	23
CTCF WILD-TYPE	75	68	60

Figure S36. Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'CTCF MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00126 (Fisher's exact test), Q value = 0.034

Table S44. Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CTCF MUTATED	0	8	3	7	4	8	14
CTCF WILD-TYPE	44	33	14	26	31	23	32

Figure S37. Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CTCF MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00645 (Fisher's exact test), Q value = 0.1

Table S45. Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CTCF MUTATED	5	15	24
CTCF WILD-TYPE	64	64	68

Figure S38. Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'CTCF MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00974 (Fisher's exact test), Q value = 0.14

Table S46. Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CTCF MUTATED	9	11	21	3
CTCF WILD-TYPE	64	32	58	42

Figure S39. Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'CTCF MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0293 (Fisher's exact test), Q value = 0.27

Table S47. Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CTCF MUTATED	0	3	11
CTCF WILD-TYPE	29	16	53

Figure S40. Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'CTCF MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0189 (Fisher's exact test), Q value = 0.21

Table S48. Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CTCF MUTATED	1	11	2
CTCF WILD-TYPE	32	37	29

Figure S41. Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'FBXW7 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 0.76

Table S49. Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
FBXW7 MUTATED	3	4	3	0
FBXW7 WILD-TYPE	9	14	8	10

'FBXW7 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.271 (Fisher's exact test), Q value = 0.7

Table S50. Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
FBXW7 MUTATED	2	3	3	1	1
FBXW7 WILD-TYPE	10	7	4	6	14

'FBXW7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.309 (Fisher's exact test), Q value = 0.72

Table S51. Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
FBXW7 MUTATED	13	23	0	0	2
FBXW7 WILD-TYPE	43	129	11	5	16

'FBXW7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0353 (Fisher's exact test), Q value = 0.3

Table S52. Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
FBXW7 MUTATED	11	2	9
FBXW7 WILD-TYPE	32	37	44

Figure S42. Get High-res Image Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'FBXW7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.249 (Fisher's exact test), Q value = 0.67

Table S53. Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
FBXW7 MUTATED	11	9	14
FBXW7 WILD-TYPE	60	63	46

'FBXW7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.479 (Fisher's exact test), Q value = 0.84

Table S54. Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
FBXW7 MUTATED	8	14	6	6
FBXW7 WILD-TYPE	60	64	25	20

'FBXW7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0455 (Fisher's exact test), Q value = 0.33

Table S55. Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
FBXW7 MUTATED	19	10	9
FBXW7 WILD-TYPE	60	75	74

Figure S43. Get High-res Image Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'FBXW7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00345 (Fisher's exact test), Q value = 0.069

Table S56. Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
FBXW7 MUTATED	12	0	4	8	5	3	6
FBXW7 WILD-TYPE	32	41	13	25	30	28	40

Figure S44. Get High-res Image Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FBXW7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.756 (Fisher's exact test), Q value = 1

Table S57. Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
FBXW7 MUTATED	11	12	11
FBXW7 WILD-TYPE	58	67	81

'FBXW7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00571 (Fisher's exact test), Q value = 0.093

Table S58. Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
FBXW7 MUTATED	12	2	7	13
FBXW7 WILD-TYPE	61	41	72	32

Figure S45. Get High-res Image Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'FBXW7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.231 (Fisher's exact test), Q value = 0.64

Table S59. Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
FBXW7 MUTATED	7	2	7
FBXW7 WILD-TYPE	22	17	57

'FBXW7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0674 (Fisher's exact test), Q value = 0.4

Table S60. Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
FBXW7 MUTATED	8	3	5
FBXW7 WILD-TYPE	25	45	26

'PIK3CA MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S61. Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
PIK3CA MUTATED	6	8	6	6
PIK3CA WILD-TYPE	6	10	5	4

'PIK3CA MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.372 (Fisher's exact test), Q value = 0.77

Table S62. Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
PIK3CA MUTATED	5	4	6	3	8
PIK3CA WILD-TYPE	7	6	1	4	7

'PIK3CA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.6 (Fisher's exact test), Q value = 0.92

Table S63. Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PIK3CA MUTATED	26	83	5	4	9
PIK3CA WILD-TYPE	30	69	6	1	9

'PIK3CA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.747 (Fisher's exact test), Q value = 1

Table S64. Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PIK3CA MUTATED	21	22	26
PIK3CA WILD-TYPE	22	17	27

'PIK3CA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.204 (Fisher's exact test), Q value = 0.6

Table S65. Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PIK3CA MUTATED	42	37	26
PIK3CA WILD-TYPE	29	35	34

'PIK3CA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.39 (Fisher's exact test), Q value = 0.77

Table S66. Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PIK3CA MUTATED	35	36	17	17
PIK3CA WILD-TYPE	33	42	14	9

'PIK3CA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.733 (Fisher's exact test), Q value = 0.99

Table S67. Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PIK3CA MUTATED	39	45	46
PIK3CA WILD-TYPE	40	40	37

'PIK3CA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.552 (Fisher's exact test), Q value = 0.89

Table S68. Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PIK3CA MUTATED	21	22	6	17	23	17	24
PIK3CA WILD-TYPE	23	19	11	16	12	14	22

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.221 (Fisher's exact test), Q value = 0.63

Table S69. Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PIK3CA MUTATED	31	42	54
PIK3CA WILD-TYPE	38	37	38

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.428 (Fisher's exact test), Q value = 0.79

Table S70. Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PIK3CA MUTATED	37	23	47	20
PIK3CA WILD-TYPE	36	20	32	25

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.347 (Fisher's exact test), Q value = 0.76

Table S71. Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
PIK3CA MUTATED	13	8	37
PIK3CA WILD-TYPE	16	11	27

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.637 (Fisher's exact test), Q value = 0.95

Table S72. Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
PIK3CA MUTATED	15	27	16
PIK3CA WILD-TYPE	18	21	15

'ARID1A MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.266 (Fisher's exact test), Q value = 0.69

Table S73. Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ARID1A MUTATED	5	3	4	5
ARID1A WILD-TYPE	7	15	7	5

'ARID1A MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0722 (Fisher's exact test), Q value = 0.42

Table S74. Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ARID1A MUTATED	5	0	3	4	5
ARID1A WILD-TYPE	7	10	4	3	10

'ARID1A MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S75. Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ARID1A MUTATED	3	67	2	1	7
ARID1A WILD-TYPE	53	85	9	4	11

Figure S46. Get High-res Image Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ARID1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 0.49

Table S76. Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ARID1A MUTATED	9	16	20
ARID1A WILD-TYPE	34	23	33

'ARID1A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0558 (Fisher's exact test), Q value = 0.36

Table S77. Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ARID1A MUTATED	29	26	13
ARID1A WILD-TYPE	42	46	47

'ARID1A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.31 (Fisher's exact test), Q value = 0.72

Table S78. Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ARID1A MUTATED	28	23	11	6
ARID1A WILD-TYPE	40	55	20	20

'ARID1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0214 (Fisher's exact test), Q value = 0.23

Table S79. Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ARID1A MUTATED	17	33	33
ARID1A WILD-TYPE	62	52	50

Figure S47. Get High-res Image Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'ARID1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S80. Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ARID1A MUTATED	3	15	3	13	18	6	25
ARID1A WILD-TYPE	41	26	14	20	17	25	21

Figure S48. Get High-res Image Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ARID1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0533 (Fisher's exact test), Q value = 0.35

Table S81. Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ARID1A MUTATED	17	24	39
ARID1A WILD-TYPE	52	55	53

'ARID1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 2e-04 (Fisher's exact test), Q value = 0.0089

Table S82. Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ARID1A MUTATED	25	14	37	4
ARID1A WILD-TYPE	48	29	42	41

Figure S49. Get High-res Image Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.14 (Fisher's exact test), Q value = 0.54

Table S83. Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ARID1A MUTATED	6	7	27
ARID1A WILD-TYPE	23	12	37

'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.129 (Fisher's exact test), Q value = 0.53

Table S84. Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ARID1A MUTATED	8	22	10
ARID1A WILD-TYPE	25	26	21

'ARHGAP35 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.225 (Fisher's exact test), Q value = 0.63

Table S85. Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ARHGAP35 MUTATED	4	5	3	0
ARHGAP35 WILD-TYPE	8	13	8	10

'ARHGAP35 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S86. Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ARHGAP35 MUTATED	4	2	2	1	3
ARHGAP35 WILD-TYPE	8	8	5	6	12

'ARHGAP35 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.576 (Fisher's exact test), Q value = 0.9

Table S87. Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ARHGAP35 MUTATED	8	24	0	0	4
ARHGAP35 WILD-TYPE	48	128	11	5	14

'ARHGAP35 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S88. Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ARHGAP35 MUTATED	6	5	8
ARHGAP35 WILD-TYPE	37	34	45

'ARHGAP35 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 0.59

Table S89. Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ARHGAP35 MUTATED	9	9	14
ARHGAP35 WILD-TYPE	62	63	46

'ARHGAP35 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 0.7

Table S90. Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ARHGAP35 MUTATED	7	15	7	3
ARHGAP35 WILD-TYPE	61	63	24	23

'ARHGAP35 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.227 (Fisher's exact test), Q value = 0.64

Table S91. Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ARHGAP35 MUTATED	16	11	9
ARHGAP35 WILD-TYPE	63	74	74

'ARHGAP35 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00693 (Fisher's exact test), Q value = 0.11

Table S92. Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ARHGAP35 MUTATED	5	1	5	10	7	4	4
ARHGAP35 WILD-TYPE	39	40	12	23	28	27	42

Figure S50. Get High-res Image Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ARHGAP35 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.56 (Fisher's exact test), Q value = 0.89

Table S93. Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ARHGAP35 MUTATED	10	13	10
ARHGAP35 WILD-TYPE	59	66	82

'ARHGAP35 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.172 (Fisher's exact test), Q value = 0.58

Table S94. Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ARHGAP35 MUTATED	13	3	8	9
ARHGAP35 WILD-TYPE	60	40	71	36

'ARHGAP35 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.319 (Fisher's exact test), Q value = 0.73

Table S95. Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ARHGAP35 MUTATED	6	2	6
ARHGAP35 WILD-TYPE	23	17	58

'ARHGAP35 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.205 (Fisher's exact test), Q value = 0.6

Table S96. Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ARHGAP35 MUTATED	6	3	5
ARHGAP35 WILD-TYPE	27	45	26

'KRAS MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 0.77

Table S97. Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
KRAS MUTATED	4	2	3	1
KRAS WILD-TYPE	8	16	8	9

'KRAS MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0354 (Fisher's exact test), Q value = 0.3

Table S98. Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
KRAS MUTATED	3	0	3	3	1
KRAS WILD-TYPE	9	10	4	4	14

Figure S51. Get High-res Image Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'KRAS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00027 (Fisher's exact test), Q value = 0.011

Table S99. Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
KRAS MUTATED	2	43	2	0	2
KRAS WILD-TYPE	54	109	9	5	16

Figure S52. Get High-res Image Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'KRAS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0529 (Fisher's exact test), Q value = 0.35

Table S100. Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
KRAS MUTATED	5	8	17
KRAS WILD-TYPE	38	31	36

'KRAS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0586 (Fisher's exact test), Q value = 0.37

Table S101. Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
KRAS MUTATED	18	16	6
KRAS WILD-TYPE	53	56	54

'KRAS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.371 (Fisher's exact test), Q value = 0.77

Table S102. Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
KRAS MUTATED	16	11	8	5
KRAS WILD-TYPE	52	67	23	21

'KRAS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.217 (Fisher's exact test), Q value = 0.62

Table S103. Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
KRAS MUTATED	12	18	22
KRAS WILD-TYPE	67	67	61

'KRAS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00028 (Fisher's exact test), Q value = 0.011

Table S104. Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
KRAS MUTATED	4	2	1	13	10	10	12
KRAS WILD-TYPE	40	39	16	20	25	21	34

Figure S53. Get High-res Image Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'KRAS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0148 (Fisher's exact test), Q value = 0.19

Table S105. Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
KRAS MUTATED	7	18	26
KRAS WILD-TYPE	62	61	66

Figure S54. Get High-res Image Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'KRAS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.015 (Fisher's exact test), Q value = 0.19

Table S106. Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
KRAS MUTATED	20	4	22	5
KRAS WILD-TYPE	53	39	57	40

Figure S55. Get High-res Image Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'KRAS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.706 (Fisher's exact test), Q value = 0.98

Table S107. Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
KRAS MUTATED	5	5	15
KRAS WILD-TYPE	24	14	49

'KRAS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 0.59

Table S108. Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
KRAS MUTATED	4	14	7
KRAS WILD-TYPE	29	34	24

'CTNNB1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S109. Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
CTNNB1 MUTATED	0	3	4	10
CTNNB1 WILD-TYPE	12	15	7	0

Figure S56. Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 3e-05 (Fisher's exact test), Q value = 0.002

Table S110. Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
CTNNB1 MUTATED	4	0	1	0	12
CTNNB1 WILD-TYPE	8	10	6	7	3

Figure S57. Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S111. Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CTNNB1 MUTATED	1	58	5	2	6
CTNNB1 WILD-TYPE	55	94	6	3	12

Figure S58. Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CTNNB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00295 (Fisher's exact test), Q value = 0.061

Table S112. Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CTNNB1 MUTATED	4	13	20
CTNNB1 WILD-TYPE	39	26	33

Figure S59. Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'CTNNB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.375 (Fisher's exact test), Q value = 0.77

Table S113. Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CTNNB1 MUTATED	19	27	18
CTNNB1 WILD-TYPE	52	45	42

'CTNNB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.207 (Fisher's exact test), Q value = 0.6

Table S114. Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CTNNB1 MUTATED	25	25	5	9
CTNNB1 WILD-TYPE	43	53	26	17

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S115. Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CTNNB1 MUTATED	9	48	17
CTNNB1 WILD-TYPE	70	37	66

Figure S60. Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S116. Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CTNNB1 MUTATED	0	39	1	7	14	10	3
CTNNB1 WILD-TYPE	44	2	16	26	21	21	43

Figure S61. Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S117. Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CTNNB1 MUTATED	5	46	20
CTNNB1 WILD-TYPE	64	33	72

Figure S62. Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S118. Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CTNNB1 MUTATED	20	38	11	2
CTNNB1 WILD-TYPE	53	5	68	43

Figure S63. Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00028 (Fisher's exact test), Q value = 0.011

Table S119. Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CTNNB1 MUTATED	0	8	17
CTNNB1 WILD-TYPE	29	11	47

Figure S64. Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00226 (Fisher's exact test), Q value = 0.052

Table S120. Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CTNNB1 MUTATED	1	15	9
CTNNB1 WILD-TYPE	32	33	22

Figure S65. Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ZFHX3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.374 (Fisher's exact test), Q value = 0.77

Table S121. Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ZFHX3 MUTATED	6	6	2	2
ZFHX3 WILD-TYPE	6	12	9	8

'ZFHX3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 0.59

Table S122. Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ZFHX3 MUTATED	4	2	2	5	3
ZFHX3 WILD-TYPE	8	8	5	2	12

'ZFHX3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0331 (Fisher's exact test), Q value = 0.29

Table S123. Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZFHX3 MUTATED	3	34	2	0	3
ZFHX3 WILD-TYPE	53	118	9	5	15

Figure S66. Get High-res Image Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZFHX3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0146 (Fisher's exact test), Q value = 0.19

Table S124. Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZFHX3 MUTATED	5	1	12
ZFHX3 WILD-TYPE	38	38	41

Figure S67. Get High-res Image Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'ZFHX3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.221 (Fisher's exact test), Q value = 0.63

Table S125. Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZFHX3 MUTATED	9	17	9
ZFHX3 WILD-TYPE	62	55	51

'ZFHX3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S126. Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZFHX3 MUTATED	10	14	7	4
ZFHX3 WILD-TYPE	58	64	24	22

'ZFHX3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S127. Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZFHX3 MUTATED	13	17	14
ZFHX3 WILD-TYPE	66	68	69

'ZFHX3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00725 (Fisher's exact test), Q value = 0.11

Table S128. Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZFHX3 MUTATED	4	3	2	12	11	4	8
ZFHX3 WILD-TYPE	40	38	15	21	24	27	38

Figure S68. Get High-res Image Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZFHX3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.162 (Fisher's exact test), Q value = 0.58

Table S129. Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZFHX3 MUTATED	7	17	17
ZFHX3 WILD-TYPE	62	62	75

'ZFHX3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0227 (Fisher's exact test), Q value = 0.23

Table S130. Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZFHX3 MUTATED	19	3	15	4
ZFHX3 WILD-TYPE	54	40	64	41

Figure S69. Get High-res Image Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'ZFHX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 0.92

Table S131. Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZFHX3 MUTATED	3	4	8
ZFHX3 WILD-TYPE	26	15	56

'ZFHX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.526 (Fisher's exact test), Q value = 0.87

Table S132. Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZFHX3 MUTATED	4	5	6
ZFHX3 WILD-TYPE	29	43	25

'SPOP MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.349 (Fisher's exact test), Q value = 0.77

Table S133. Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
SPOP MUTATED	2	1	0	2
SPOP WILD-TYPE	10	17	11	8

'SPOP MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.674 (Fisher's exact test), Q value = 0.97

Table S134. Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
SPOP MUTATED	0	1	1	1	2
SPOP WILD-TYPE	12	9	6	6	13

'SPOP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.574 (Fisher's exact test), Q value = 0.9

Table S135. Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SPOP MUTATED	3	15	1	1	1
SPOP WILD-TYPE	53	137	10	4	17

'SPOP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.421 (Fisher's exact test), Q value = 0.79

Table S136. Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SPOP MUTATED	4	1	5
SPOP WILD-TYPE	39	38	48

'SPOP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.905 (Fisher's exact test), Q value = 1

Table S137. Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SPOP MUTATED	6	7	4
SPOP WILD-TYPE	65	65	56

'SPOP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.42 (Fisher's exact test), Q value = 0.79

Table S138. Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SPOP MUTATED	3	8	4	2
SPOP WILD-TYPE	65	70	27	24

'SPOP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 0.79

Table S139. Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SPOP MUTATED	6	10	5
SPOP WILD-TYPE	73	75	78

'SPOP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.108 (Fisher's exact test), Q value = 0.5

Table S140. Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SPOP MUTATED	2	1	2	4	7	1	4
SPOP WILD-TYPE	42	40	15	29	28	30	42

'SPOP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.847 (Fisher's exact test), Q value = 1

Table S141. Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SPOP MUTATED	7	7	7
SPOP WILD-TYPE	62	72	85

'SPOP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.367 (Fisher's exact test), Q value = 0.77

Table S142. Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SPOP MUTATED	9	5	4	3
SPOP WILD-TYPE	64	38	75	42

'SPOP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0831 (Fisher's exact test), Q value = 0.44

Table S143. Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
SPOP MUTATED	3	3	2
SPOP WILD-TYPE	26	16	62

'SPOP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.418 (Fisher's exact test), Q value = 0.79

Table S144. Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
SPOP MUTATED	4	3	1
SPOP WILD-TYPE	29	45	30

'FGFR2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.385 (Fisher's exact test), Q value = 0.77

Table S145. Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
FGFR2 MUTATED	3	2	1	0
FGFR2 WILD-TYPE	9	16	10	10

'FGFR2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.364 (Fisher's exact test), Q value = 0.77

Table S146. Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
FGFR2 MUTATED	2	0	1	2	1
FGFR2 WILD-TYPE	10	10	6	5	14

'FGFR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.269 (Fisher's exact test), Q value = 0.7

Table S147. Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
FGFR2 MUTATED	3	22	2	1	2
FGFR2 WILD-TYPE	53	130	9	4	16

'FGFR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S148. Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
FGFR2 MUTATED	5	5	7
FGFR2 WILD-TYPE	38	34	46

'FGFR2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.445 (Fisher's exact test), Q value = 0.81

Table S149. Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
FGFR2 MUTATED	12	7	8
FGFR2 WILD-TYPE	59	65	52

'FGFR2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.717 (Fisher's exact test), Q value = 0.98

Table S150. Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
FGFR2 MUTATED	11	8	4	4
FGFR2 WILD-TYPE	57	70	27	22

'FGFR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S151. Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
FGFR2 MUTATED	10	11	10
FGFR2 WILD-TYPE	69	74	73

'FGFR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.075 (Fisher's exact test), Q value = 0.43

Table S152. Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
FGFR2 MUTATED	2	2	2	8	7	3	7
FGFR2 WILD-TYPE	42	39	15	25	28	28	39

'FGFR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.805 (Fisher's exact test), Q value = 1

Table S153. Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
FGFR2 MUTATED	7	11	12
FGFR2 WILD-TYPE	62	68	80

'FGFR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.105 (Fisher's exact test), Q value = 0.49

Table S154. Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
FGFR2 MUTATED	12	1	11	6
FGFR2 WILD-TYPE	61	42	68	39

'FGFR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.291 (Fisher's exact test), Q value = 0.7

Table S155. Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
FGFR2 MUTATED	6	3	6
FGFR2 WILD-TYPE	23	16	58

'FGFR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S156. Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
FGFR2 MUTATED	4	7	4
FGFR2 WILD-TYPE	29	41	27

'TCP11L2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0414 (Fisher's exact test), Q value = 0.32

Table S157. Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
TCP11L2 MUTATED	4	2	0	0
TCP11L2 WILD-TYPE	8	16	11	10

Figure S70. Get High-res Image Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'TCP11L2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0187 (Fisher's exact test), Q value = 0.21

Table S158. Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
TCP11L2 MUTATED	2	0	1	3	0
TCP11L2 WILD-TYPE	10	10	6	4	15

Figure S71. Get High-res Image Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'TCP11L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.121 (Fisher's exact test), Q value = 0.52

Table S159. Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
TCP11L2 MUTATED	0	12	0	0	2
TCP11L2 WILD-TYPE	56	140	11	5	16

'TCP11L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.108 (Fisher's exact test), Q value = 0.5

Table S160. Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
TCP11L2 MUTATED	1	0	5
TCP11L2 WILD-TYPE	42	39	48

'TCP11L2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.756 (Fisher's exact test), Q value = 1

Table S161. Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
TCP11L2 MUTATED	5	3	4
TCP11L2 WILD-TYPE	66	69	56

'TCP11L2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.647 (Fisher's exact test), Q value = 0.96

Table S162. Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
TCP11L2 MUTATED	4	6	2	0
TCP11L2 WILD-TYPE	64	72	29	26

'TCP11L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.274 (Fisher's exact test), Q value = 0.7

Table S163. Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
TCP11L2 MUTATED	6	6	2
TCP11L2 WILD-TYPE	73	79	81

'TCP11L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00015 (Fisher's exact test), Q value = 0.0072

Table S164. Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
TCP11L2 MUTATED	0	0	1	6	6	0	1
TCP11L2 WILD-TYPE	44	41	16	27	29	31	45

Figure S72. Get High-res Image Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TCP11L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.423 (Fisher's exact test), Q value = 0.79

Table S165. Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
TCP11L2 MUTATED	4	6	3
TCP11L2 WILD-TYPE	65	73	89

'TCP11L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.376 (Fisher's exact test), Q value = 0.77

Table S166. Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
TCP11L2 MUTATED	7	1	3	2
TCP11L2 WILD-TYPE	66	42	76	43

'TCP11L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.805 (Fisher's exact test), Q value = 1

Table S167. Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
TCP11L2 MUTATED	1	1	2
TCP11L2 WILD-TYPE	28	18	62

'TCP11L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.815 (Fisher's exact test), Q value = 1

Table S168. Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
TCP11L2 MUTATED	2	1	1
TCP11L2 WILD-TYPE	31	47	30

'VPS11 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.384 (Fisher's exact test), Q value = 0.77

Table S169. Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
VPS11 MUTATED	2	1	0	0
VPS11 WILD-TYPE	10	17	11	10

'VPS11 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 0.7

Table S170. Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
VPS11 MUTATED	1	0	1	1	0
VPS11 WILD-TYPE	11	10	6	6	15

'VPS11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.461 (Fisher's exact test), Q value = 0.82

Table S171. Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
VPS11 MUTATED	1	8	0	0	2
VPS11 WILD-TYPE	55	144	11	5	16

'VPS11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S172. Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
VPS11 MUTATED	2	1	1
VPS11 WILD-TYPE	41	38	52

'VPS11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 0.8

Table S173. Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
VPS11 MUTATED	5	2	2
VPS11 WILD-TYPE	66	70	58

'VPS11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.393 (Fisher's exact test), Q value = 0.77

Table S174. Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
VPS11 MUTATED	3	3	3	0
VPS11 WILD-TYPE	65	75	28	26

'VPS11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 0.58

Table S175. Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
VPS11 MUTATED	4	6	1
VPS11 WILD-TYPE	75	79	82

'VPS11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0133 (Fisher's exact test), Q value = 0.18

Table S176. Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
VPS11 MUTATED	1	0	1	3	5	1	0
VPS11 WILD-TYPE	43	41	16	30	30	30	46

Figure S73. Get High-res Image Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'VPS11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.291 (Fisher's exact test), Q value = 0.7

Table S177. Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
VPS11 MUTATED	5	4	2
VPS11 WILD-TYPE	64	75	90

'VPS11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 0.51

Table S178. Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
VPS11 MUTATED	6	0	2	3
VPS11 WILD-TYPE	67	43	77	42

'PPP2R1A MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0744 (Fisher's exact test), Q value = 0.43

Table S179. Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
PPP2R1A MUTATED	3	5	0	0
PPP2R1A WILD-TYPE	9	13	11	10

'PPP2R1A MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0555 (Fisher's exact test), Q value = 0.36

Table S180. Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
PPP2R1A MUTATED	4	2	0	2	0
PPP2R1A WILD-TYPE	8	8	7	5	15

'PPP2R1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0828 (Fisher's exact test), Q value = 0.44

Table S181. Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PPP2R1A MUTATED	12	12	1	0	1
PPP2R1A WILD-TYPE	44	140	10	5	17

'PPP2R1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0142 (Fisher's exact test), Q value = 0.18

Table S182. Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PPP2R1A MUTATED	10	1	5
PPP2R1A WILD-TYPE	33	38	48

Figure S74. Get High-res Image Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'PPP2R1A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 0.53

Table S183. Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PPP2R1A MUTATED	5	7	11
PPP2R1A WILD-TYPE	66	65	49

'PPP2R1A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.065 (Fisher's exact test), Q value = 0.39

Table S184. Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PPP2R1A MUTATED	5	15	2	1
PPP2R1A WILD-TYPE	63	63	29	25

'PPP2R1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00315 (Fisher's exact test), Q value = 0.064

Table S185. Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PPP2R1A MUTATED	17	7	4
PPP2R1A WILD-TYPE	62	78	79

Figure S75. Get High-res Image Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'PPP2R1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0224 (Fisher's exact test), Q value = 0.23

Table S186. Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PPP2R1A MUTATED	12	3	2	4	4	1	2
PPP2R1A WILD-TYPE	32	38	15	29	31	30	44

Figure S76. Get High-res Image Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PPP2R1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0162 (Fisher's exact test), Q value = 0.19

Table S187. Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PPP2R1A MUTATED	14	6	6
PPP2R1A WILD-TYPE	55	73	86

Figure S77. Get High-res Image Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'PPP2R1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.001 (Fisher's exact test), Q value = 0.029

Table S188. Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PPP2R1A MUTATED	6	3	4	13
PPP2R1A WILD-TYPE	67	40	75	32

Figure S78. Get High-res Image Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PPP2R1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0107 (Fisher's exact test), Q value = 0.15

Table S189. Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
PPP2R1A MUTATED	8	4	4
PPP2R1A WILD-TYPE	21	15	60

Figure S79. Get High-res Image Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'PPP2R1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0315 (Fisher's exact test), Q value = 0.28

Table S190. Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
PPP2R1A MUTATED	9	3	4
PPP2R1A WILD-TYPE	24	45	27

Figure S80. Get High-res Image Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MAX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.37 (Fisher's exact test), Q value = 0.77

Table S191. Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MAX MUTATED	0	8	0	0	1
MAX WILD-TYPE	56	144	11	5	17

'MAX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 0.9

Table S192. Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MAX MUTATED	1	3	2
MAX WILD-TYPE	42	36	51

'MAX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.601 (Fisher's exact test), Q value = 0.92

Table S193. Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MAX MUTATED	3	4	1
MAX WILD-TYPE	68	68	59

'MAX MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.721 (Fisher's exact test), Q value = 0.99

Table S194. Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MAX MUTATED	3	3	2	0
MAX WILD-TYPE	65	75	29	26

'MAX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S195. Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MAX MUTATED	3	4	2
MAX WILD-TYPE	76	81	81

'MAX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.289 (Fisher's exact test), Q value = 0.7

Table S196. Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MAX MUTATED	0	1	1	2	3	0	2
MAX WILD-TYPE	44	40	16	31	32	31	44

'MAX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.524 (Fisher's exact test), Q value = 0.87

Table S197. Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MAX MUTATED	1	4	4
MAX WILD-TYPE	68	75	88

'MAX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.966 (Fisher's exact test), Q value = 1

Table S198. Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MAX MUTATED	3	2	3	1
MAX WILD-TYPE	70	41	76	44

'MAX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 0.59

Table S199. Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MAX MUTATED	0	2	2
MAX WILD-TYPE	29	17	62

'MAX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.813 (Fisher's exact test), Q value = 1

Table S200. Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MAX MUTATED	2	1	1
MAX WILD-TYPE	31	47	30

'SOX17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0494 (Fisher's exact test), Q value = 0.34

Table S201. Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SOX17 MUTATED	0	4	1	1	1
SOX17 WILD-TYPE	56	148	10	4	17

Figure S81. Get High-res Image Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'SOX17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.14 (Fisher's exact test), Q value = 0.54

Table S202. Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SOX17 MUTATED	0	3	1
SOX17 WILD-TYPE	43	36	52

'SOX17 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S203. Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SOX17 MUTATED	2	3	1
SOX17 WILD-TYPE	69	69	59

'SOX17 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S204. Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SOX17 MUTATED	2	2	1	1
SOX17 WILD-TYPE	66	76	30	25

'SOX17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.202 (Fisher's exact test), Q value = 0.6

Table S205. Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SOX17 MUTATED	1	1	5
SOX17 WILD-TYPE	78	84	78

'SOX17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.488 (Fisher's exact test), Q value = 0.85

Table S206. Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SOX17 MUTATED	1	0	0	0	2	1	3
SOX17 WILD-TYPE	43	41	17	33	33	30	43

'SOX17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.798 (Fisher's exact test), Q value = 1

Table S207. Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SOX17 MUTATED	1	3	3
SOX17 WILD-TYPE	68	76	89

'SOX17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.482 (Fisher's exact test), Q value = 0.84

Table S208. Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SOX17 MUTATED	2	1	4	0
SOX17 WILD-TYPE	71	42	75	45

'CCND1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.63 (Fisher's exact test), Q value = 0.95

Table S209. Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
CCND1 MUTATED	2	1	0	1
CCND1 WILD-TYPE	10	17	11	9

'CCND1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.808 (Fisher's exact test), Q value = 1

Table S210. Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
CCND1 MUTATED	1	0	1	1	1
CCND1 WILD-TYPE	11	10	6	6	14

'CCND1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 0.53

Table S211. Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CCND1 MUTATED	0	13	0	0	1
CCND1 WILD-TYPE	56	139	11	5	17

'CCND1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.262 (Fisher's exact test), Q value = 0.69

Table S212. Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CCND1 MUTATED	1	1	5
CCND1 WILD-TYPE	42	38	48

'CCND1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.847 (Fisher's exact test), Q value = 1

Table S213. Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CCND1 MUTATED	4	4	2
CCND1 WILD-TYPE	67	68	58

'CCND1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S214. Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CCND1 MUTATED	2	5	2	1
CCND1 WILD-TYPE	66	73	29	25

'CCND1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.482 (Fisher's exact test), Q value = 0.84

Table S215. Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CCND1 MUTATED	3	7	4
CCND1 WILD-TYPE	76	78	79

'CCND1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0476 (Fisher's exact test), Q value = 0.33

Table S216. Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CCND1 MUTATED	0	1	0	5	4	1	3
CCND1 WILD-TYPE	44	40	17	28	31	30	43

Figure S82. Get High-res Image Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CCND1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0805 (Fisher's exact test), Q value = 0.43

Table S217. Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CCND1 MUTATED	1	8	5
CCND1 WILD-TYPE	68	71	87

'CCND1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.594 (Fisher's exact test), Q value = 0.92

Table S218. Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CCND1 MUTATED	6	2	5	1
CCND1 WILD-TYPE	67	41	74	44

'CCND1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.495 (Fisher's exact test), Q value = 0.85

Table S219. Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CCND1 MUTATED	0	1	3
CCND1 WILD-TYPE	29	18	61

'CCND1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.38 (Fisher's exact test), Q value = 0.77

Table S220. Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CCND1 MUTATED	0	3	1
CCND1 WILD-TYPE	33	45	30

'NRAS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.75 (Fisher's exact test), Q value = 1

Table S221. Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
NRAS MUTATED	1	7	0	0	1
NRAS WILD-TYPE	55	145	11	5	17

'NRAS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S222. Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
NRAS MUTATED	3	2	1
NRAS WILD-TYPE	68	70	59

'NRAS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.049 (Fisher's exact test), Q value = 0.34

Table S223. Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
NRAS MUTATED	2	0	2	2
NRAS WILD-TYPE	66	78	29	24

Figure S83. Get High-res Image Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'NRAS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.641 (Fisher's exact test), Q value = 0.95

Table S224. Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
NRAS MUTATED	4	3	2
NRAS WILD-TYPE	75	82	81

'NRAS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S225. Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
NRAS MUTATED	1	2	1	1	2	0	2
NRAS WILD-TYPE	43	39	16	32	33	31	44

'NRAS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S226. Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
NRAS MUTATED	3	3	3
NRAS WILD-TYPE	66	76	89

'NRAS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S227. Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
NRAS MUTATED	3	1	4	1
NRAS WILD-TYPE	70	42	75	44

'EP300 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S228. Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
EP300 MUTATED	1	1	1	0
EP300 WILD-TYPE	11	17	10	10

'EP300 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.913 (Fisher's exact test), Q value = 1

Table S229. Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
EP300 MUTATED	1	0	1	0	1
EP300 WILD-TYPE	11	10	6	7	14

'EP300 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0153 (Fisher's exact test), Q value = 0.19

Table S230. Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
EP300 MUTATED	0	18	0	1	2
EP300 WILD-TYPE	56	134	11	4	16

Figure S84. Get High-res Image Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'EP300 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.228 (Fisher's exact test), Q value = 0.64

Table S231. Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
EP300 MUTATED	1	2	6
EP300 WILD-TYPE	42	37	47

'EP300 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.109 (Fisher's exact test), Q value = 0.5

Table S232. Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
EP300 MUTATED	9	9	2
EP300 WILD-TYPE	62	63	58

'EP300 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.119 (Fisher's exact test), Q value = 0.52

Table S233. Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
EP300 MUTATED	9	6	5	0
EP300 WILD-TYPE	59	72	26	26

'EP300 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 0.81

Table S234. Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
EP300 MUTATED	4	9	7
EP300 WILD-TYPE	75	76	76

'EP300 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0314 (Fisher's exact test), Q value = 0.28

Table S235. Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
EP300 MUTATED	0	2	2	6	5	1	4
EP300 WILD-TYPE	44	39	15	27	30	30	42

Figure S85. Get High-res Image Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'EP300 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.657 (Fisher's exact test), Q value = 0.96

Table S236. Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
EP300 MUTATED	5	9	7
EP300 WILD-TYPE	64	70	85

'EP300 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.275 (Fisher's exact test), Q value = 0.7

Table S237. Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
EP300 MUTATED	8	3	9	1
EP300 WILD-TYPE	65	40	70	44

'EP300 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.368 (Fisher's exact test), Q value = 0.77

Table S238. Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
EP300 MUTATED	0	1	5
EP300 WILD-TYPE	29	18	59

'EP300 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.372 (Fisher's exact test), Q value = 0.77

Table S239. Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
EP300 MUTATED	2	1	3
EP300 WILD-TYPE	31	47	28

'KLHL8 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 0.77

Table S240. Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
KLHL8 MUTATED	2	1	0	0
KLHL8 WILD-TYPE	10	17	11	10

'KLHL8 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 0.7

Table S241. Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
KLHL8 MUTATED	1	0	1	1	0
KLHL8 WILD-TYPE	11	10	6	6	15

'KLHL8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.147 (Fisher's exact test), Q value = 0.55

Table S242. Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
KLHL8 MUTATED	0	10	0	0	2
KLHL8 WILD-TYPE	56	142	11	5	16

'KLHL8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 0.86

Table S243. Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
KLHL8 MUTATED	1	1	4
KLHL8 WILD-TYPE	42	38	49

'KLHL8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.713 (Fisher's exact test), Q value = 0.98

Table S244. Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
KLHL8 MUTATED	3	5	2
KLHL8 WILD-TYPE	68	67	58

'KLHL8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.965 (Fisher's exact test), Q value = 1

Table S245. Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
KLHL8 MUTATED	3	4	2	1
KLHL8 WILD-TYPE	65	74	29	25

'KLHL8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.233 (Fisher's exact test), Q value = 0.64

Table S246. Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
KLHL8 MUTATED	3	7	2
KLHL8 WILD-TYPE	76	78	81

'KLHL8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00465 (Fisher's exact test), Q value = 0.084

Table S247. Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
KLHL8 MUTATED	0	1	1	6	3	0	1
KLHL8 WILD-TYPE	44	40	16	27	32	31	45

Figure S86. Get High-res Image Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'KLHL8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.459 (Fisher's exact test), Q value = 0.82

Table S248. Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
KLHL8 MUTATED	3	6	3
KLHL8 WILD-TYPE	66	73	89

'KLHL8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.911 (Fisher's exact test), Q value = 1

Table S249. Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
KLHL8 MUTATED	4	2	3	3
KLHL8 WILD-TYPE	69	41	76	42

'KLHL8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 0.81

Table S250. Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
KLHL8 MUTATED	0	1	4
KLHL8 WILD-TYPE	29	18	60

'KLHL8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S251. Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
KLHL8 MUTATED	2	2	1
KLHL8 WILD-TYPE	31	46	30

'ALG8 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S252. Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ALG8 MUTATED	1	1	1	0
ALG8 WILD-TYPE	11	17	10	10

'ALG8 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.205 (Fisher's exact test), Q value = 0.6

Table S253. Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ALG8 MUTATED	2	0	1	0	0
ALG8 WILD-TYPE	10	10	6	7	15

'ALG8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.655 (Fisher's exact test), Q value = 0.96

Table S254. Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ALG8 MUTATED	1	9	0	0	1
ALG8 WILD-TYPE	55	143	11	5	17

'ALG8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.189 (Fisher's exact test), Q value = 0.59

Table S255. Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ALG8 MUTATED	1	0	4
ALG8 WILD-TYPE	42	39	49

'ALG8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.048 (Fisher's exact test), Q value = 0.33

Table S256. Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ALG8 MUTATED	2	8	1
ALG8 WILD-TYPE	69	64	59

Figure S87. Get High-res Image Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'ALG8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.396 (Fisher's exact test), Q value = 0.77

Table S257. Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ALG8 MUTATED	3	6	0	2
ALG8 WILD-TYPE	65	72	31	24

'ALG8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S258. Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ALG8 MUTATED	3	4	4
ALG8 WILD-TYPE	76	81	79

'ALG8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.172 (Fisher's exact test), Q value = 0.58

Table S259. Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ALG8 MUTATED	0	1	1	4	2	2	1
ALG8 WILD-TYPE	44	40	16	29	33	29	45

'ALG8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.797 (Fisher's exact test), Q value = 1

Table S260. Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ALG8 MUTATED	2	4	5
ALG8 WILD-TYPE	67	75	87

'ALG8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.717 (Fisher's exact test), Q value = 0.98

Table S261. Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ALG8 MUTATED	5	2	3	1
ALG8 WILD-TYPE	68	41	76	44

'ALG8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 0.77

Table S262. Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ALG8 MUTATED	1	1	1
ALG8 WILD-TYPE	28	18	63

'ALG8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S263. Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ALG8 MUTATED	1	1	1
ALG8 WILD-TYPE	32	47	30

'GNPTAB MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 0.81

Table S264. Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
GNPTAB MUTATED	1	3	0	0
GNPTAB WILD-TYPE	11	15	11	10

'GNPTAB MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0797 (Fisher's exact test), Q value = 0.43

Table S265. Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
GNPTAB MUTATED	3	0	1	0	0
GNPTAB WILD-TYPE	9	10	6	7	15

'GNPTAB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 0.51

Table S266. Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
GNPTAB MUTATED	1	16	0	0	3
GNPTAB WILD-TYPE	55	136	11	5	15

'GNPTAB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.116 (Fisher's exact test), Q value = 0.51

Table S267. Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
GNPTAB MUTATED	3	1	8
GNPTAB WILD-TYPE	40	38	45

'GNPTAB MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.711 (Fisher's exact test), Q value = 0.98

Table S268. Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
GNPTAB MUTATED	6	8	4
GNPTAB WILD-TYPE	65	64	56

'GNPTAB MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.632 (Fisher's exact test), Q value = 0.95

Table S269. Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
GNPTAB MUTATED	5	8	4	1
GNPTAB WILD-TYPE	63	70	27	25

'GNPTAB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.153 (Fisher's exact test), Q value = 0.56

Table S270. Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
GNPTAB MUTATED	9	8	3
GNPTAB WILD-TYPE	70	77	80

'GNPTAB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00053 (Fisher's exact test), Q value = 0.018

Table S271. Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
GNPTAB MUTATED	1	1	1	7	8	1	1
GNPTAB WILD-TYPE	43	40	16	26	27	30	45

Figure S88. Get High-res Image Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'GNPTAB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.832 (Fisher's exact test), Q value = 1

Table S272. Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
GNPTAB MUTATED	6	7	6
GNPTAB WILD-TYPE	63	72	86

'GNPTAB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.222 (Fisher's exact test), Q value = 0.63

Table S273. Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
GNPTAB MUTATED	10	2	4	3
GNPTAB WILD-TYPE	63	41	75	42

'GNPTAB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.701 (Fisher's exact test), Q value = 0.98

Table S274. Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
GNPTAB MUTATED	3	2	4
GNPTAB WILD-TYPE	26	17	60

'GNPTAB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.415 (Fisher's exact test), Q value = 0.79

Table S275. Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
GNPTAB MUTATED	4	2	3
GNPTAB WILD-TYPE	29	46	28

'SIN3A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0287 (Fisher's exact test), Q value = 0.27

Table S276. Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SIN3A MUTATED	0	16	1	0	3
SIN3A WILD-TYPE	56	136	10	5	15

Figure S89. Get High-res Image Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'SIN3A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 0.74

Table S277. Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SIN3A MUTATED	4	2	8
SIN3A WILD-TYPE	39	37	45

'SIN3A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.321 (Fisher's exact test), Q value = 0.73

Table S278. Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SIN3A MUTATED	9	7	3
SIN3A WILD-TYPE	62	65	57

'SIN3A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0787 (Fisher's exact test), Q value = 0.43

Table S279. Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SIN3A MUTATED	4	6	7	2
SIN3A WILD-TYPE	64	72	24	24

'SIN3A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00947 (Fisher's exact test), Q value = 0.14

Table S280. Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SIN3A MUTATED	6	13	2
SIN3A WILD-TYPE	73	72	81

Figure S90. Get High-res Image Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'SIN3A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00023 (Fisher's exact test), Q value = 0.0099

Table S281. Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SIN3A MUTATED	0	3	1	5	10	1	1
SIN3A WILD-TYPE	44	38	16	28	25	30	45

Figure S91. Get High-res Image Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SIN3A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0453 (Fisher's exact test), Q value = 0.33

Table S282. Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SIN3A MUTATED	8	10	3
SIN3A WILD-TYPE	61	69	89

Figure S92. Get High-res Image Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'SIN3A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00029 (Fisher's exact test), Q value = 0.011

Table S283. Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SIN3A MUTATED	15	2	1	3
SIN3A WILD-TYPE	58	41	78	42

Figure S93. Get High-res Image Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'SIN3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 0.85

Table S284. Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
SIN3A MUTATED	4	1	4
SIN3A WILD-TYPE	25	18	60

'SIN3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.418 (Fisher's exact test), Q value = 0.79

Table S285. Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
SIN3A MUTATED	4	2	3
SIN3A WILD-TYPE	29	46	28

'ARID5B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.961 (Fisher's exact test), Q value = 1

Table S286. Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ARID5B MUTATED	3	3	2	2
ARID5B WILD-TYPE	9	15	9	8

'ARID5B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.139 (Fisher's exact test), Q value = 0.54

Table S287. Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ARID5B MUTATED	4	0	3	1	2
ARID5B WILD-TYPE	8	10	4	6	13

'ARID5B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00481 (Fisher's exact test), Q value = 0.085

Table S288. Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ARID5B MUTATED	0	25	1	0	2
ARID5B WILD-TYPE	56	127	10	5	16

Figure S94. Get High-res Image Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ARID5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.188 (Fisher's exact test), Q value = 0.59

Table S289. Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ARID5B MUTATED	1	1	6
ARID5B WILD-TYPE	42	38	47

'ARID5B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 0.53

Table S290. Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ARID5B MUTATED	5	13	6
ARID5B WILD-TYPE	66	59	54

'ARID5B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S291. Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ARID5B MUTATED	9	8	3	4
ARID5B WILD-TYPE	59	70	28	22

'ARID5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.164 (Fisher's exact test), Q value = 0.58

Table S292. Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ARID5B MUTATED	5	13	11
ARID5B WILD-TYPE	74	72	72

'ARID5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0429 (Fisher's exact test), Q value = 0.32

Table S293. Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ARID5B MUTATED	1	2	1	7	7	5	6
ARID5B WILD-TYPE	43	39	16	26	28	26	40

Figure S95. Get High-res Image Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ARID5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.154 (Fisher's exact test), Q value = 0.56

Table S294. Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ARID5B MUTATED	5	7	15
ARID5B WILD-TYPE	64	72	77

'ARID5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.109 (Fisher's exact test), Q value = 0.5

Table S295. Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ARID5B MUTATED	11	4	11	1
ARID5B WILD-TYPE	62	39	68	44

'ARID5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.193 (Fisher's exact test), Q value = 0.59

Table S296. Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ARID5B MUTATED	0	2	4
ARID5B WILD-TYPE	29	17	60

'ARID5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.655 (Fisher's exact test), Q value = 0.96

Table S297. Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ARID5B MUTATED	1	4	1
ARID5B WILD-TYPE	32	44	30

'NFE2L2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0904 (Fisher's exact test), Q value = 0.46

Table S298. Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
NFE2L2 MUTATED	0	1	3	0
NFE2L2 WILD-TYPE	12	17	8	10

'NFE2L2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.32 (Fisher's exact test), Q value = 0.73

Table S299. Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
NFE2L2 MUTATED	1	0	2	0	1
NFE2L2 WILD-TYPE	11	10	5	7	14

'NFE2L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0191 (Fisher's exact test), Q value = 0.21

Table S300. Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
NFE2L2 MUTATED	0	9	2	0	3
NFE2L2 WILD-TYPE	56	143	9	5	15

Figure S96. Get High-res Image Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'NFE2L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.183 (Fisher's exact test), Q value = 0.59

Table S301. Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
NFE2L2 MUTATED	0	3	3
NFE2L2 WILD-TYPE	43	36	50

'NFE2L2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.275 (Fisher's exact test), Q value = 0.7

Table S302. Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
NFE2L2 MUTATED	7	3	2
NFE2L2 WILD-TYPE	64	69	58

'NFE2L2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0543 (Fisher's exact test), Q value = 0.36

Table S303. Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
NFE2L2 MUTATED	7	1	3	1
NFE2L2 WILD-TYPE	61	77	28	25

'NFE2L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00144 (Fisher's exact test), Q value = 0.038

Table S304. Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
NFE2L2 MUTATED	1	2	11
NFE2L2 WILD-TYPE	78	83	72

Figure S97. Get High-res Image Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'NFE2L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0186 (Fisher's exact test), Q value = 0.21

Table S305. Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
NFE2L2 MUTATED	0	0	2	2	1	3	6
NFE2L2 WILD-TYPE	44	41	15	31	34	28	40

Figure S98. Get High-res Image Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NFE2L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 0.53

Table S306. Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
NFE2L2 MUTATED	3	2	9
NFE2L2 WILD-TYPE	66	77	83

'NFE2L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0474 (Fisher's exact test), Q value = 0.33

Table S307. Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
NFE2L2 MUTATED	4	0	9	1
NFE2L2 WILD-TYPE	69	43	70	44

Figure S99. Get High-res Image Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'NFE2L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.283 (Fisher's exact test), Q value = 0.7

Table S308. Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
NFE2L2 MUTATED	0	0	5
NFE2L2 WILD-TYPE	29	19	59

'NFE2L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.178 (Fisher's exact test), Q value = 0.59

Table S309. Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
NFE2L2 MUTATED	0	4	1
NFE2L2 WILD-TYPE	33	44	30

'ZNF471 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.683 (Fisher's exact test), Q value = 0.97

Table S310. Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ZNF471 MUTATED	2	1	1	0
ZNF471 WILD-TYPE	10	17	10	10

'ZNF471 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0916 (Fisher's exact test), Q value = 0.46

Table S311. Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ZNF471 MUTATED	1	0	2	1	0
ZNF471 WILD-TYPE	11	10	5	6	15

'ZNF471 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 0.5

Table S312. Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF471 MUTATED	0	14	0	0	1
ZNF471 WILD-TYPE	56	138	11	5	17

'ZNF471 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.558 (Fisher's exact test), Q value = 0.89

Table S313. Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF471 MUTATED	1	2	4
ZNF471 WILD-TYPE	42	37	49

'ZNF471 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.938 (Fisher's exact test), Q value = 1

Table S314. Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF471 MUTATED	5	4	4
ZNF471 WILD-TYPE	66	68	56

'ZNF471 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.448 (Fisher's exact test), Q value = 0.81

Table S315. Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF471 MUTATED	3	5	4	1
ZNF471 WILD-TYPE	65	73	27	25

'ZNF471 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 0.79

Table S316. Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF471 MUTATED	5	7	3
ZNF471 WILD-TYPE	74	78	80

'ZNF471 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 9e-05 (Fisher's exact test), Q value = 0.0049

Table S317. Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF471 MUTATED	0	0	0	6	7	1	1
ZNF471 WILD-TYPE	44	41	17	27	28	30	45

Figure S100. Get High-res Image Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF471 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.59

Table S318. Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF471 MUTATED	3	8	3
ZNF471 WILD-TYPE	66	71	89

'ZNF471 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.221 (Fisher's exact test), Q value = 0.63

Table S319. Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF471 MUTATED	8	2	3	1
ZNF471 WILD-TYPE	65	41	76	44

'ZNF471 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S320. Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZNF471 MUTATED	1	1	3
ZNF471 WILD-TYPE	28	18	61

'ZNF471 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.326 (Fisher's exact test), Q value = 0.74

Table S321. Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZNF471 MUTATED	1	1	3
ZNF471 WILD-TYPE	32	47	28

'MORC4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.58 (Fisher's exact test), Q value = 0.9

Table S322. Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
MORC4 MUTATED	1	3	0	1
MORC4 WILD-TYPE	11	15	11	9

'MORC4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S323. Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
MORC4 MUTATED	2	1	1	0	1
MORC4 WILD-TYPE	10	9	6	7	14

'MORC4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.105 (Fisher's exact test), Q value = 0.49

Table S324. Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MORC4 MUTATED	1	17	0	1	1
MORC4 WILD-TYPE	55	135	11	4	17

'MORC4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 0.8

Table S325. Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MORC4 MUTATED	2	5	5
MORC4 WILD-TYPE	41	34	48

'MORC4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0345 (Fisher's exact test), Q value = 0.3

Table S326. Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MORC4 MUTATED	4	11	2
MORC4 WILD-TYPE	67	61	58

Figure S101. Get High-res Image Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'MORC4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0581 (Fisher's exact test), Q value = 0.37

Table S327. Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MORC4 MUTATED	4	7	6	0
MORC4 WILD-TYPE	64	71	25	26

'MORC4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.131 (Fisher's exact test), Q value = 0.53

Table S328. Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MORC4 MUTATED	7	10	3
MORC4 WILD-TYPE	72	75	80

'MORC4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0841 (Fisher's exact test), Q value = 0.44

Table S329. Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MORC4 MUTATED	1	4	1	6	5	2	1
MORC4 WILD-TYPE	43	37	16	27	30	29	45

'MORC4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0234 (Fisher's exact test), Q value = 0.23

Table S330. Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MORC4 MUTATED	3	12	4
MORC4 WILD-TYPE	66	67	88

Figure S102. Get High-res Image Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'MORC4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 0.53

Table S331. Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MORC4 MUTATED	10	4	3	2
MORC4 WILD-TYPE	63	39	76	43

'MORC4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0329 (Fisher's exact test), Q value = 0.29

Table S332. Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MORC4 MUTATED	0	4	5
MORC4 WILD-TYPE	29	15	59

Figure S103. Get High-res Image Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'MORC4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.379 (Fisher's exact test), Q value = 0.77

Table S333. Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MORC4 MUTATED	1	4	4
MORC4 WILD-TYPE	32	44	27

'SELP MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.383 (Fisher's exact test), Q value = 0.77

Table S334. Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
SELP MUTATED	2	1	0	0
SELP WILD-TYPE	10	17	11	10

'SELP MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 0.7

Table S335. Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
SELP MUTATED	1	0	1	1	0
SELP WILD-TYPE	11	10	6	6	15

'SELP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.23 (Fisher's exact test), Q value = 0.64

Table S336. Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SELP MUTATED	0	8	1	0	1
SELP WILD-TYPE	56	144	10	5	17

'SELP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S337. Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SELP MUTATED	1	1	1
SELP WILD-TYPE	42	38	52

'SELP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S338. Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SELP MUTATED	3	3	2
SELP WILD-TYPE	68	69	58

'SELP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.522 (Fisher's exact test), Q value = 0.87

Table S339. Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SELP MUTATED	1	4	2	1
SELP WILD-TYPE	67	74	29	25

'SELP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.264 (Fisher's exact test), Q value = 0.69

Table S340. Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SELP MUTATED	4	5	1
SELP WILD-TYPE	75	80	82

'SELP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00735 (Fisher's exact test), Q value = 0.11

Table S341. Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SELP MUTATED	0	0	2	3	4	0	1
SELP WILD-TYPE	44	41	15	30	31	31	45

Figure S104. Get High-res Image Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SELP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.481 (Fisher's exact test), Q value = 0.84

Table S342. Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SELP MUTATED	4	3	2
SELP WILD-TYPE	65	76	90

'SELP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.123 (Fisher's exact test), Q value = 0.53

Table S343. Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SELP MUTATED	6	1	2	0
SELP WILD-TYPE	67	42	77	45

'RBMX MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.193 (Fisher's exact test), Q value = 0.59

Table S344. Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
RBMX MUTATED	3	2	0	0
RBMX WILD-TYPE	9	16	11	10

'RBMX MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.093 (Fisher's exact test), Q value = 0.46

Table S345. Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
RBMX MUTATED	2	0	1	2	0
RBMX WILD-TYPE	10	10	6	5	15

'RBMX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 0.58

Table S346. Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
RBMX MUTATED	0	11	0	0	0
RBMX WILD-TYPE	56	141	11	5	18

'RBMX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S347. Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
RBMX MUTATED	1	0	2
RBMX WILD-TYPE	42	39	51

'RBMX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.56 (Fisher's exact test), Q value = 0.89

Table S348. Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
RBMX MUTATED	4	2	4
RBMX WILD-TYPE	67	70	56

'RBMX MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.749 (Fisher's exact test), Q value = 1

Table S349. Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
RBMX MUTATED	4	4	2	0
RBMX WILD-TYPE	64	74	29	26

'RBMX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.611 (Fisher's exact test), Q value = 0.93

Table S350. Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
RBMX MUTATED	3	6	3
RBMX WILD-TYPE	76	79	80

'RBMX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.111 (Fisher's exact test), Q value = 0.51

Table S351. Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
RBMX MUTATED	1	0	1	5	2	1	2
RBMX WILD-TYPE	43	41	16	28	33	30	44

'RBMX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S352. Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
RBMX MUTATED	3	5	4
RBMX WILD-TYPE	66	74	88

'RBMX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00478 (Fisher's exact test), Q value = 0.085

Table S353. Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
RBMX MUTATED	9	0	3	0
RBMX WILD-TYPE	64	43	76	45

Figure S105. Get High-res Image Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'RBMX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.562 (Fisher's exact test), Q value = 0.89

Table S354. Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
RBMX MUTATED	0	1	2
RBMX WILD-TYPE	29	18	62

'RBMX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S355. Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
RBMX MUTATED	1	1	1
RBMX WILD-TYPE	32	47	30

'FAT1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.00618 (Fisher's exact test), Q value = 0.099

Table S356. Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
FAT1 MUTATED	6	5	0	0
FAT1 WILD-TYPE	6	13	11	10

Figure S106. Get High-res Image Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'FAT1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00146 (Fisher's exact test), Q value = 0.038

Table S357. Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
FAT1 MUTATED	4	1	1	5	0
FAT1 WILD-TYPE	8	9	6	2	15

Figure S107. Get High-res Image Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'FAT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0678 (Fisher's exact test), Q value = 0.4

Table S358. Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
FAT1 MUTATED	3	31	2	1	3
FAT1 WILD-TYPE	53	121	9	4	15

'FAT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00599 (Fisher's exact test), Q value = 0.097

Table S359. Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
FAT1 MUTATED	4	2	15
FAT1 WILD-TYPE	39	37	38

Figure S108. Get High-res Image Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'FAT1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.372 (Fisher's exact test), Q value = 0.77

Table S360. Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
FAT1 MUTATED	13	15	7
FAT1 WILD-TYPE	58	57	53

'FAT1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0719 (Fisher's exact test), Q value = 0.42

Table S361. Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
FAT1 MUTATED	13	9	10	3
FAT1 WILD-TYPE	55	69	21	23

'FAT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 0.58

Table S362. Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
FAT1 MUTATED	11	19	10
FAT1 WILD-TYPE	68	66	73

'FAT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-04 (Fisher's exact test), Q value = 0.0054

Table S363. Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
FAT1 MUTATED	2	2	2	13	11	5	5
FAT1 WILD-TYPE	42	39	15	20	24	26	41

Figure S109. Get High-res Image Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FAT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S364. Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
FAT1 MUTATED	10	14	14
FAT1 WILD-TYPE	59	65	78

'FAT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00641 (Fisher's exact test), Q value = 0.1

Table S365. Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
FAT1 MUTATED	20	3	12	3
FAT1 WILD-TYPE	53	40	67	42

Figure S110. Get High-res Image Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'FAT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S366. Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
FAT1 MUTATED	4	3	10
FAT1 WILD-TYPE	25	16	54

'FAT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.449 (Fisher's exact test), Q value = 0.81

Table S367. Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
FAT1 MUTATED	6	5	6
FAT1 WILD-TYPE	27	43	25

'MARK3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 0.53

Table S368. Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
MARK3 MUTATED	3	1	0	0
MARK3 WILD-TYPE	9	17	11	10

'MARK3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0915 (Fisher's exact test), Q value = 0.46

Table S369. Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
MARK3 MUTATED	1	0	2	1	0
MARK3 WILD-TYPE	11	10	5	6	15

'MARK3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.161 (Fisher's exact test), Q value = 0.58

Table S370. Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MARK3 MUTATED	0	9	0	0	2
MARK3 WILD-TYPE	56	143	11	5	16

'MARK3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0377 (Fisher's exact test), Q value = 0.31

Table S371. Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MARK3 MUTATED	0	0	4
MARK3 WILD-TYPE	43	39	49

Figure S111. Get High-res Image Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'MARK3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.517 (Fisher's exact test), Q value = 0.87

Table S372. Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MARK3 MUTATED	2	5	3
MARK3 WILD-TYPE	69	67	57

'MARK3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 0.72

Table S373. Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MARK3 MUTATED	2	5	3	0
MARK3 WILD-TYPE	66	73	28	26

'MARK3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.549 (Fisher's exact test), Q value = 0.89

Table S374. Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MARK3 MUTATED	4	5	2
MARK3 WILD-TYPE	75	80	81

'MARK3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00051 (Fisher's exact test), Q value = 0.017

Table S375. Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MARK3 MUTATED	0	0	0	3	6	2	0
MARK3 WILD-TYPE	44	41	17	30	29	29	46

Figure S112. Get High-res Image Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MARK3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.398 (Fisher's exact test), Q value = 0.77

Table S376. Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MARK3 MUTATED	3	5	2
MARK3 WILD-TYPE	66	74	90

'MARK3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.313 (Fisher's exact test), Q value = 0.72

Table S377. Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MARK3 MUTATED	6	1	2	1
MARK3 WILD-TYPE	67	42	77	44

'SOS1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.631 (Fisher's exact test), Q value = 0.95

Table S378. Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
SOS1 MUTATED	1	1	2	0
SOS1 WILD-TYPE	11	17	9	10

'SOS1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.808 (Fisher's exact test), Q value = 1

Table S379. Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
SOS1 MUTATED	1	0	1	1	1
SOS1 WILD-TYPE	11	10	6	6	14

'SOS1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0748 (Fisher's exact test), Q value = 0.43

Table S380. Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SOS1 MUTATED	0	11	0	1	0
SOS1 WILD-TYPE	56	141	11	4	18

'SOS1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.556 (Fisher's exact test), Q value = 0.89

Table S381. Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SOS1 MUTATED	2	0	2
SOS1 WILD-TYPE	41	39	51

'SOS1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.245 (Fisher's exact test), Q value = 0.66

Table S382. Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SOS1 MUTATED	1	5	3
SOS1 WILD-TYPE	70	67	57

'SOS1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.169 (Fisher's exact test), Q value = 0.58

Table S383. Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SOS1 MUTATED	1	6	2	0
SOS1 WILD-TYPE	67	72	29	26

'SOS1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.863 (Fisher's exact test), Q value = 1

Table S384. Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SOS1 MUTATED	4	3	4
SOS1 WILD-TYPE	75	82	79

'SOS1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.039 (Fisher's exact test), Q value = 0.31

Table S385. Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SOS1 MUTATED	0	0	1	2	4	3	1
SOS1 WILD-TYPE	44	41	16	31	31	28	45

Figure S113. Get High-res Image Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SOS1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 0.63

Table S386. Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SOS1 MUTATED	1	6	4
SOS1 WILD-TYPE	68	73	88

'SOS1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.654 (Fisher's exact test), Q value = 0.96

Table S387. Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SOS1 MUTATED	5	1	4	1
SOS1 WILD-TYPE	68	42	75	44

'SOS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 0.53

Table S388. Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
SOS1 MUTATED	1	2	1
SOS1 WILD-TYPE	28	17	63

'SOS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.168 (Fisher's exact test), Q value = 0.58

Table S389. Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
SOS1 MUTATED	2	0	2
SOS1 WILD-TYPE	31	48	29

'RBBP6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 0.9

Table S390. Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
RBBP6 MUTATED	1	3	0	1
RBBP6 WILD-TYPE	11	15	11	9

'RBBP6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0212 (Fisher's exact test), Q value = 0.23

Table S391. Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
RBBP6 MUTATED	4	0	0	1	0
RBBP6 WILD-TYPE	8	10	7	6	15

Figure S114. Get High-res Image Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'RBBP6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0127 (Fisher's exact test), Q value = 0.17

Table S392. Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
RBBP6 MUTATED	0	19	0	0	3
RBBP6 WILD-TYPE	56	133	11	5	15

Figure S115. Get High-res Image Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'RBBP6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.926 (Fisher's exact test), Q value = 1

Table S393. Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
RBBP6 MUTATED	3	3	5
RBBP6 WILD-TYPE	40	36	48

'RBBP6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.671 (Fisher's exact test), Q value = 0.97

Table S394. Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
RBBP6 MUTATED	8	8	4
RBBP6 WILD-TYPE	63	64	56

'RBBP6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.728 (Fisher's exact test), Q value = 0.99

Table S395. Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
RBBP6 MUTATED	7	8	4	1
RBBP6 WILD-TYPE	61	70	27	25

'RBBP6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0498 (Fisher's exact test), Q value = 0.34

Table S396. Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
RBBP6 MUTATED	7	12	3
RBBP6 WILD-TYPE	72	73	80

Figure S116. Get High-res Image Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'RBBP6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00012 (Fisher's exact test), Q value = 0.0062

Table S397. Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
RBBP6 MUTATED	0	2	1	7	9	2	1
RBBP6 WILD-TYPE	44	39	16	26	26	29	45

Figure S117. Get High-res Image Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RBBP6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S398. Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
RBBP6 MUTATED	5	8	8
RBBP6 WILD-TYPE	64	71	84

'RBBP6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00431 (Fisher's exact test), Q value = 0.081

Table S399. Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
RBBP6 MUTATED	14	2	4	1
RBBP6 WILD-TYPE	59	41	75	44

Figure S118. Get High-res Image Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'RBBP6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0344 (Fisher's exact test), Q value = 0.3

Table S400. Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
RBBP6 MUTATED	0	4	5
RBBP6 WILD-TYPE	29	15	59

Figure S119. Get High-res Image Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'RBBP6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0321 (Fisher's exact test), Q value = 0.29

Table S401. Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
RBBP6 MUTATED	1	2	6
RBBP6 WILD-TYPE	32	46	25

Figure S120. Get High-res Image Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ZNF263 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.498 (Fisher's exact test), Q value = 0.85

Table S402. Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF263 MUTATED	0	7	0	0	0
ZNF263 WILD-TYPE	56	145	11	5	18

'ZNF263 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.385 (Fisher's exact test), Q value = 0.77

Table S403. Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF263 MUTATED	1	0	3
ZNF263 WILD-TYPE	42	39	50

'ZNF263 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0192 (Fisher's exact test), Q value = 0.21

Table S404. Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF263 MUTATED	1	6	0
ZNF263 WILD-TYPE	70	66	60

Figure S121. Get High-res Image Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'ZNF263 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.708 (Fisher's exact test), Q value = 0.98

Table S405. Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF263 MUTATED	2	3	2	0
ZNF263 WILD-TYPE	66	75	29	26

'ZNF263 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.511 (Fisher's exact test), Q value = 0.87

Table S406. Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF263 MUTATED	1	4	2
ZNF263 WILD-TYPE	78	81	81

'ZNF263 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0335 (Fisher's exact test), Q value = 0.29

Table S407. Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF263 MUTATED	0	0	0	3	2	2	0
ZNF263 WILD-TYPE	44	41	17	30	33	29	46

Figure S122. Get High-res Image Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF263 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.206 (Fisher's exact test), Q value = 0.6

Table S408. Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF263 MUTATED	0	3	4
ZNF263 WILD-TYPE	69	76	88

'ZNF263 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.714 (Fisher's exact test), Q value = 0.98

Table S409. Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF263 MUTATED	3	1	3	0
ZNF263 WILD-TYPE	70	42	76	45

'ZNF263 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.805 (Fisher's exact test), Q value = 1

Table S410. Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZNF263 MUTATED	1	1	2
ZNF263 WILD-TYPE	28	18	62

'ZNF263 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0349 (Fisher's exact test), Q value = 0.3

Table S411. Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZNF263 MUTATED	1	0	3
ZNF263 WILD-TYPE	32	48	28

Figure S123. Get High-res Image Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'INTS7 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 0.77

Table S412. Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
INTS7 MUTATED	2	1	0	0
INTS7 WILD-TYPE	10	17	11	10

'INTS7 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 0.7

Table S413. Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
INTS7 MUTATED	1	0	1	1	0
INTS7 WILD-TYPE	11	10	6	6	15

'INTS7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.42 (Fisher's exact test), Q value = 0.79

Table S414. Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
INTS7 MUTATED	0	8	0	0	0
INTS7 WILD-TYPE	56	144	11	5	18

'INTS7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.321 (Fisher's exact test), Q value = 0.73

Table S415. Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
INTS7 MUTATED	1	3	4
INTS7 WILD-TYPE	70	69	56

'INTS7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.16 (Fisher's exact test), Q value = 0.57

Table S416. Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
INTS7 MUTATED	1	4	3	0
INTS7 WILD-TYPE	67	74	28	26

'INTS7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0748 (Fisher's exact test), Q value = 0.43

Table S417. Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
INTS7 MUTATED	3	5	0
INTS7 WILD-TYPE	76	80	83

'INTS7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00498 (Fisher's exact test), Q value = 0.087

Table S418. Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
INTS7 MUTATED	0	1	0	2	5	0	0
INTS7 WILD-TYPE	44	40	17	31	30	31	46

Figure S124. Get High-res Image Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'INTS7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 0.75

Table S419. Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
INTS7 MUTATED	2	4	1
INTS7 WILD-TYPE	67	75	91

'INTS7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 0.52

Table S420. Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
INTS7 MUTATED	4	2	0	1
INTS7 WILD-TYPE	69	41	79	44

'L1TD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0722 (Fisher's exact test), Q value = 0.42

Table S421. Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
L1TD1 MUTATED	0	14	0	0	2
L1TD1 WILD-TYPE	56	138	11	5	16

'L1TD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.148 (Fisher's exact test), Q value = 0.55

Table S422. Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
L1TD1 MUTATED	2	1	7
L1TD1 WILD-TYPE	41	38	46

'L1TD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S423. Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
L1TD1 MUTATED	4	6	3
L1TD1 WILD-TYPE	67	66	57

'L1TD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.372 (Fisher's exact test), Q value = 0.77

Table S424. Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
L1TD1 MUTATED	2	7	3	1
L1TD1 WILD-TYPE	66	71	28	25

'L1TD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.402 (Fisher's exact test), Q value = 0.77

Table S425. Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
L1TD1 MUTATED	7	6	3
L1TD1 WILD-TYPE	72	79	80

'L1TD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00105 (Fisher's exact test), Q value = 0.03

Table S426. Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
L1TD1 MUTATED	0	1	1	5	7	0	2
L1TD1 WILD-TYPE	44	40	16	28	28	31	44

Figure S125. Get High-res Image Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'L1TD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S427. Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
L1TD1 MUTATED	4	6	5
L1TD1 WILD-TYPE	65	73	87

'L1TD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.283 (Fisher's exact test), Q value = 0.7

Table S428. Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
L1TD1 MUTATED	8	2	4	1
L1TD1 WILD-TYPE	65	41	75	44

'L1TD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.746 (Fisher's exact test), Q value = 1

Table S429. Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
L1TD1 MUTATED	1	2	4
L1TD1 WILD-TYPE	28	17	60

'L1TD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.551 (Fisher's exact test), Q value = 0.89

Table S430. Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
L1TD1 MUTATED	2	2	3
L1TD1 WILD-TYPE	31	46	28

'NAT1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.379 (Fisher's exact test), Q value = 0.77

Table S431. Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
NAT1 MUTATED	2	1	0	0
NAT1 WILD-TYPE	10	17	11	10

'NAT1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0777 (Fisher's exact test), Q value = 0.43

Table S432. Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
NAT1 MUTATED	1	0	0	2	0
NAT1 WILD-TYPE	11	10	7	5	15

'NAT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.433 (Fisher's exact test), Q value = 0.79

Table S433. Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
NAT1 MUTATED	0	6	0	0	1
NAT1 WILD-TYPE	56	146	11	5	17

'NAT1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S434. Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
NAT1 MUTATED	3	2	1
NAT1 WILD-TYPE	68	70	59

'NAT1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S435. Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
NAT1 MUTATED	2	2	1	1
NAT1 WILD-TYPE	66	76	30	25

'NAT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.405 (Fisher's exact test), Q value = 0.78

Table S436. Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
NAT1 MUTATED	2	4	1
NAT1 WILD-TYPE	77	81	82

'NAT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00233 (Fisher's exact test), Q value = 0.053

Table S437. Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
NAT1 MUTATED	0	0	0	3	4	0	0
NAT1 WILD-TYPE	44	41	17	30	31	31	46

Figure S126. Get High-res Image Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NAT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S438. Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
NAT1 MUTATED	2	2	3
NAT1 WILD-TYPE	67	77	89

'NAT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.284 (Fisher's exact test), Q value = 0.7

Table S439. Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
NAT1 MUTATED	4	0	3	0
NAT1 WILD-TYPE	69	43	76	45

'JAKMIP2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.379 (Fisher's exact test), Q value = 0.77

Table S440. Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
JAKMIP2 MUTATED	2	1	0	0
JAKMIP2 WILD-TYPE	10	17	11	10

'JAKMIP2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.284 (Fisher's exact test), Q value = 0.7

Table S441. Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
JAKMIP2 MUTATED	1	0	1	1	0
JAKMIP2 WILD-TYPE	11	10	6	6	15

'JAKMIP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 0.53

Table S442. Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
JAKMIP2 MUTATED	0	9	1	0	2
JAKMIP2 WILD-TYPE	56	143	10	5	16

'JAKMIP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.558 (Fisher's exact test), Q value = 0.89

Table S443. Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
JAKMIP2 MUTATED	2	0	2
JAKMIP2 WILD-TYPE	41	39	51

'JAKMIP2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.515 (Fisher's exact test), Q value = 0.87

Table S444. Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
JAKMIP2 MUTATED	2	5	3
JAKMIP2 WILD-TYPE	69	67	57

'JAKMIP2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.103 (Fisher's exact test), Q value = 0.49

Table S445. Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
JAKMIP2 MUTATED	1	6	3	0
JAKMIP2 WILD-TYPE	67	72	28	26

'JAKMIP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0674 (Fisher's exact test), Q value = 0.4

Table S446. Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
JAKMIP2 MUTATED	7	4	1
JAKMIP2 WILD-TYPE	72	81	82

'JAKMIP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00063 (Fisher's exact test), Q value = 0.02

Table S447. Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
JAKMIP2 MUTATED	0	0	2	3	6	0	1
JAKMIP2 WILD-TYPE	44	41	15	30	29	31	45

Figure S127. Get High-res Image Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'JAKMIP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0874 (Fisher's exact test), Q value = 0.45

Table S448. Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
JAKMIP2 MUTATED	4	6	1
JAKMIP2 WILD-TYPE	65	73	91

'JAKMIP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.165 (Fisher's exact test), Q value = 0.58

Table S449. Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
JAKMIP2 MUTATED	7	1	2	1
JAKMIP2 WILD-TYPE	66	42	77	44

'ING1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.149 (Fisher's exact test), Q value = 0.55

Table S450. Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ING1 MUTATED	0	10	0	0	2
ING1 WILD-TYPE	56	142	11	5	16

'ING1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.713 (Fisher's exact test), Q value = 0.98

Table S451. Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ING1 MUTATED	3	1	3
ING1 WILD-TYPE	40	38	50

'ING1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 0.59

Table S452. Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ING1 MUTATED	6	5	1
ING1 WILD-TYPE	65	67	59

'ING1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.673 (Fisher's exact test), Q value = 0.97

Table S453. Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ING1 MUTATED	5	5	2	0
ING1 WILD-TYPE	63	73	29	26

'ING1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.655 (Fisher's exact test), Q value = 0.96

Table S454. Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ING1 MUTATED	5	3	4
ING1 WILD-TYPE	74	82	79

'ING1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0578 (Fisher's exact test), Q value = 0.37

Table S455. Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ING1 MUTATED	0	1	1	2	5	0	3
ING1 WILD-TYPE	44	40	16	31	30	31	43

'ING1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.926 (Fisher's exact test), Q value = 1

Table S456. Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ING1 MUTATED	3	3	5
ING1 WILD-TYPE	66	76	87

'ING1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.04 (Fisher's exact test), Q value = 0.31

Table S457. Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ING1 MUTATED	7	0	4	0
ING1 WILD-TYPE	66	43	75	45

Figure S128. Get High-res Image Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'ING1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0156 (Fisher's exact test), Q value = 0.19

Table S458. Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ING1 MUTATED	0	4	2
ING1 WILD-TYPE	29	15	62

Figure S129. Get High-res Image Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'ING1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0995 (Fisher's exact test), Q value = 0.47

Table S459. Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ING1 MUTATED	1	1	4
ING1 WILD-TYPE	32	47	27

'CCDC6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S460. Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CCDC6 MUTATED	2	4	0	0	0
CCDC6 WILD-TYPE	54	148	11	5	18

'CCDC6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.518 (Fisher's exact test), Q value = 0.87

Table S461. Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CCDC6 MUTATED	3	1	1
CCDC6 WILD-TYPE	40	38	52

'CCDC6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S462. Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CCDC6 MUTATED	3	2	1
CCDC6 WILD-TYPE	68	70	59

'CCDC6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.476 (Fisher's exact test), Q value = 0.83

Table S463. Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CCDC6 MUTATED	1	2	2	1
CCDC6 WILD-TYPE	67	76	29	25

'CCDC6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 0.81

Table S464. Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CCDC6 MUTATED	3	1	2
CCDC6 WILD-TYPE	76	84	81

'CCDC6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.243 (Fisher's exact test), Q value = 0.66

Table S465. Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CCDC6 MUTATED	1	0	2	1	1	0	1
CCDC6 WILD-TYPE	43	41	15	32	34	31	45

'CCDC6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.079 (Fisher's exact test), Q value = 0.43

Table S466. Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CCDC6 MUTATED	4	0	2
CCDC6 WILD-TYPE	65	79	90

'CCDC6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.568 (Fisher's exact test), Q value = 0.89

Table S467. Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CCDC6 MUTATED	2	0	2	2
CCDC6 WILD-TYPE	71	43	77	43

'CCDC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.564 (Fisher's exact test), Q value = 0.89

Table S468. Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CCDC6 MUTATED	2	1	2
CCDC6 WILD-TYPE	27	18	62

'CCDC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.447 (Fisher's exact test), Q value = 0.81

Table S469. Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CCDC6 MUTATED	3	1	1
CCDC6 WILD-TYPE	30	47	30

'ZNF781 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.268 (Fisher's exact test), Q value = 0.7

Table S470. Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF781 MUTATED	0	10	0	0	0
ZNF781 WILD-TYPE	56	142	11	5	18

'ZNF781 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S471. Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF781 MUTATED	1	2	3
ZNF781 WILD-TYPE	42	37	50

'ZNF781 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.367 (Fisher's exact test), Q value = 0.77

Table S472. Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF781 MUTATED	5	4	1
ZNF781 WILD-TYPE	66	68	59

'ZNF781 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.691 (Fisher's exact test), Q value = 0.97

Table S473. Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF781 MUTATED	2	4	2	2
ZNF781 WILD-TYPE	66	74	29	24

'ZNF781 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.526 (Fisher's exact test), Q value = 0.87

Table S474. Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF781 MUTATED	3	5	2
ZNF781 WILD-TYPE	76	80	81

'ZNF781 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0137 (Fisher's exact test), Q value = 0.18

Table S475. Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF781 MUTATED	1	0	0	5	3	0	1
ZNF781 WILD-TYPE	43	41	17	28	32	31	45

Figure S130. Get High-res Image Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF781 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.527 (Fisher's exact test), Q value = 0.87

Table S476. Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF781 MUTATED	1	4	4
ZNF781 WILD-TYPE	68	75	88

'ZNF781 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.569 (Fisher's exact test), Q value = 0.89

Table S477. Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF781 MUTATED	5	1	2	1
ZNF781 WILD-TYPE	68	42	77	44

'ZNF781 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S478. Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZNF781 MUTATED	1	1	3
ZNF781 WILD-TYPE	28	18	61

'ZNF781 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.323 (Fisher's exact test), Q value = 0.73

Table S479. Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZNF781 MUTATED	1	1	3
ZNF781 WILD-TYPE	32	47	28

'MKI67 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0234 (Fisher's exact test), Q value = 0.23

Table S480. Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
MKI67 MUTATED	6	4	0	1
MKI67 WILD-TYPE	6	14	11	9

Figure S131. Get High-res Image Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'MKI67 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0157 (Fisher's exact test), Q value = 0.19

Table S481. Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
MKI67 MUTATED	4	0	2	4	1
MKI67 WILD-TYPE	8	10	5	3	14

Figure S132. Get High-res Image Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'MKI67 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00163 (Fisher's exact test), Q value = 0.041

Table S482. Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MKI67 MUTATED	0	26	0	0	3
MKI67 WILD-TYPE	56	126	11	5	15

Figure S133. Get High-res Image Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'MKI67 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.323 (Fisher's exact test), Q value = 0.73

Table S483. Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MKI67 MUTATED	2	3	7
MKI67 WILD-TYPE	41	36	46

'MKI67 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 0.67

Table S484. Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MKI67 MUTATED	13	9	5
MKI67 WILD-TYPE	58	63	55

'MKI67 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.672 (Fisher's exact test), Q value = 0.97

Table S485. Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MKI67 MUTATED	11	9	5	2
MKI67 WILD-TYPE	57	69	26	24

'MKI67 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0643 (Fisher's exact test), Q value = 0.39

Table S486. Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MKI67 MUTATED	9	15	5
MKI67 WILD-TYPE	70	70	78

'MKI67 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00013 (Fisher's exact test), Q value = 0.0065

Table S487. Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MKI67 MUTATED	1	3	2	11	8	1	3
MKI67 WILD-TYPE	43	38	15	22	27	30	43

Figure S134. Get High-res Image Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MKI67 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 0.53

Table S488. Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MKI67 MUTATED	4	13	11
MKI67 WILD-TYPE	65	66	81

'MKI67 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0431 (Fisher's exact test), Q value = 0.32

Table S489. Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MKI67 MUTATED	15	2	8	3
MKI67 WILD-TYPE	58	41	71	42

Figure S135. Get High-res Image Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'MKI67 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S490. Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MKI67 MUTATED	3	2	6
MKI67 WILD-TYPE	26	17	58

'MKI67 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0249 (Fisher's exact test), Q value = 0.25

Table S491. Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MKI67 MUTATED	2	2	7
MKI67 WILD-TYPE	31	46	24

Figure S136. Get High-res Image Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'EIF2S2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.355 (Fisher's exact test), Q value = 0.77

Table S492. Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
EIF2S2 MUTATED	0	9	0	0	0
EIF2S2 WILD-TYPE	56	143	11	5	18

'EIF2S2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.735 (Fisher's exact test), Q value = 0.99

Table S493. Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
EIF2S2 MUTATED	1	1	3
EIF2S2 WILD-TYPE	42	38	50

'EIF2S2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.196 (Fisher's exact test), Q value = 0.59

Table S494. Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
EIF2S2 MUTATED	2	6	1
EIF2S2 WILD-TYPE	69	66	59

'EIF2S2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.158 (Fisher's exact test), Q value = 0.57

Table S495. Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
EIF2S2 MUTATED	1	3	3	2
EIF2S2 WILD-TYPE	67	75	28	24

'EIF2S2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.252 (Fisher's exact test), Q value = 0.67

Table S496. Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
EIF2S2 MUTATED	3	5	1
EIF2S2 WILD-TYPE	76	80	82

'EIF2S2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.372 (Fisher's exact test), Q value = 0.77

Table S497. Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
EIF2S2 MUTATED	1	1	1	2	3	1	0
EIF2S2 WILD-TYPE	43	40	16	31	32	30	46

'EIF2S2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.763 (Fisher's exact test), Q value = 1

Table S498. Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
EIF2S2 MUTATED	2	4	3
EIF2S2 WILD-TYPE	67	75	89

'EIF2S2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.516 (Fisher's exact test), Q value = 0.87

Table S499. Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
EIF2S2 MUTATED	4	2	1	2
EIF2S2 WILD-TYPE	69	41	78	43

'EIF2S2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.806 (Fisher's exact test), Q value = 1

Table S500. Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
EIF2S2 MUTATED	1	1	2
EIF2S2 WILD-TYPE	28	18	62

'EIF2S2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.814 (Fisher's exact test), Q value = 1

Table S501. Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
EIF2S2 MUTATED	2	1	1
EIF2S2 WILD-TYPE	31	47	30

'BCOR MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.69 (Fisher's exact test), Q value = 0.97

Table S502. Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
BCOR MUTATED	1	2	0	0
BCOR WILD-TYPE	11	16	11	10

'BCOR MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.203 (Fisher's exact test), Q value = 0.6

Table S503. Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
BCOR MUTATED	2	0	0	1	0
BCOR WILD-TYPE	10	10	7	6	15

'BCOR MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00176 (Fisher's exact test), Q value = 0.043

Table S504. Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
BCOR MUTATED	0	25	0	1	3
BCOR WILD-TYPE	56	127	11	4	15

Figure S137. Get High-res Image Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'BCOR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0164 (Fisher's exact test), Q value = 0.19

Table S505. Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
BCOR MUTATED	1	3	11
BCOR WILD-TYPE	42	36	42

Figure S138. Get High-res Image Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'BCOR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.195 (Fisher's exact test), Q value = 0.59

Table S506. Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
BCOR MUTATED	12	8	4
BCOR WILD-TYPE	59	64	56

'BCOR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.317 (Fisher's exact test), Q value = 0.73

Table S507. Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
BCOR MUTATED	11	6	5	2
BCOR WILD-TYPE	57	72	26	24

'BCOR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0328 (Fisher's exact test), Q value = 0.29

Table S508. Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
BCOR MUTATED	6	17	7
BCOR WILD-TYPE	73	68	76

Figure S139. Get High-res Image Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'BCOR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00443 (Fisher's exact test), Q value = 0.081

Table S509. Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
BCOR MUTATED	0	6	2	8	8	2	4
BCOR WILD-TYPE	44	35	15	25	27	29	42

Figure S140. Get High-res Image Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'BCOR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.907 (Fisher's exact test), Q value = 1

Table S510. Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
BCOR MUTATED	9	10	10
BCOR WILD-TYPE	60	69	82

'BCOR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.237 (Fisher's exact test), Q value = 0.65

Table S511. Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
BCOR MUTATED	13	6	6	4
BCOR WILD-TYPE	60	37	73	41

'BCOR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 0.72

Table S512. Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
BCOR MUTATED	2	4	6
BCOR WILD-TYPE	27	15	58

'BCOR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.93 (Fisher's exact test), Q value = 1

Table S513. Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
BCOR MUTATED	3	6	3
BCOR WILD-TYPE	30	42	28

'RASA1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.384 (Fisher's exact test), Q value = 0.77

Table S514. Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
RASA1 MUTATED	3	2	1	0
RASA1 WILD-TYPE	9	16	10	10

'RASA1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.366 (Fisher's exact test), Q value = 0.77

Table S515. Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
RASA1 MUTATED	2	0	1	2	1
RASA1 WILD-TYPE	10	10	6	5	14

'RASA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 0.51

Table S516. Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
RASA1 MUTATED	1	19	0	0	1
RASA1 WILD-TYPE	55	133	11	5	17

'RASA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.657 (Fisher's exact test), Q value = 0.96

Table S517. Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
RASA1 MUTATED	3	1	4
RASA1 WILD-TYPE	40	38	49

'RASA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.301 (Fisher's exact test), Q value = 0.71

Table S518. Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
RASA1 MUTATED	9	6	3
RASA1 WILD-TYPE	62	66	57

'RASA1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.833 (Fisher's exact test), Q value = 1

Table S519. Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
RASA1 MUTATED	6	6	4	2
RASA1 WILD-TYPE	62	72	27	24

'RASA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.582 (Fisher's exact test), Q value = 0.9

Table S520. Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
RASA1 MUTATED	7	9	5
RASA1 WILD-TYPE	72	76	78

'RASA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0624 (Fisher's exact test), Q value = 0.39

Table S521. Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
RASA1 MUTATED	2	2	2	7	4	0	4
RASA1 WILD-TYPE	42	39	15	26	31	31	42

'RASA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 0.82

Table S522. Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
RASA1 MUTATED	4	9	7
RASA1 WILD-TYPE	65	70	85

'RASA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.531 (Fisher's exact test), Q value = 0.88

Table S523. Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
RASA1 MUTATED	8	2	5	5
RASA1 WILD-TYPE	65	41	74	40

'RASA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 0.77

Table S524. Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
RASA1 MUTATED	3	2	3
RASA1 WILD-TYPE	26	17	61

'RASA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.168 (Fisher's exact test), Q value = 0.58

Table S525. Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
RASA1 MUTATED	3	1	4
RASA1 WILD-TYPE	30	47	27

'DNER MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.19 (Fisher's exact test), Q value = 0.59

Table S526. Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
DNER MUTATED	3	2	0	0
DNER WILD-TYPE	9	16	11	10

'DNER MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0926 (Fisher's exact test), Q value = 0.46

Table S527. Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
DNER MUTATED	2	0	2	1	0
DNER WILD-TYPE	10	10	5	6	15

'DNER MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0297 (Fisher's exact test), Q value = 0.27

Table S528. Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
DNER MUTATED	0	15	0	0	3
DNER WILD-TYPE	56	137	11	5	15

Figure S141. Get High-res Image Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'DNER MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.658 (Fisher's exact test), Q value = 0.96

Table S529. Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
DNER MUTATED	3	1	4
DNER WILD-TYPE	40	38	49

'DNER MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0951 (Fisher's exact test), Q value = 0.46

Table S530. Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
DNER MUTATED	7	7	1
DNER WILD-TYPE	64	65	59

'DNER MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S531. Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
DNER MUTATED	4	7	3	1
DNER WILD-TYPE	64	71	28	25

'DNER MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.867 (Fisher's exact test), Q value = 1

Table S532. Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
DNER MUTATED	6	7	5
DNER WILD-TYPE	73	78	78

'DNER MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00036 (Fisher's exact test), Q value = 0.013

Table S533. Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
DNER MUTATED	0	0	2	5	7	0	4
DNER WILD-TYPE	44	41	15	28	28	31	42

Figure S142. Get High-res Image Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'DNER MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.737 (Fisher's exact test), Q value = 0.99

Table S534. Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
DNER MUTATED	6	6	5
DNER WILD-TYPE	63	73	87

'DNER MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.56 (Fisher's exact test), Q value = 0.89

Table S535. Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
DNER MUTATED	7	1	6	3
DNER WILD-TYPE	66	42	73	42

'DNER MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.863 (Fisher's exact test), Q value = 1

Table S536. Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
DNER MUTATED	1	1	5
DNER WILD-TYPE	28	18	59

'DNER MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.479 (Fisher's exact test), Q value = 0.84

Table S537. Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
DNER MUTATED	1	3	3
DNER WILD-TYPE	32	45	28

'C9ORF23 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 0.77

Table S538. Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
C9ORF23 MUTATED	0	7	0	0	1
C9ORF23 WILD-TYPE	56	145	11	5	17

'C9ORF23 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0608 (Fisher's exact test), Q value = 0.38

Table S539. Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
C9ORF23 MUTATED	2	0	6
C9ORF23 WILD-TYPE	41	39	47

'C9ORF23 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.476 (Fisher's exact test), Q value = 0.83

Table S540. Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
C9ORF23 MUTATED	4	4	1
C9ORF23 WILD-TYPE	67	68	59

'C9ORF23 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.636 (Fisher's exact test), Q value = 0.95

Table S541. Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
C9ORF23 MUTATED	3	5	0	1
C9ORF23 WILD-TYPE	65	73	31	25

'C9ORF23 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S542. Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
C9ORF23 MUTATED	3	3	3
C9ORF23 WILD-TYPE	76	82	80

'C9ORF23 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0779 (Fisher's exact test), Q value = 0.43

Table S543. Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
C9ORF23 MUTATED	0	0	1	4	1	1	2
C9ORF23 WILD-TYPE	44	41	16	29	34	30	44

'C9ORF23 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.437 (Fisher's exact test), Q value = 0.8

Table S544. Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
C9ORF23 MUTATED	1	3	5
C9ORF23 WILD-TYPE	68	76	87

'C9ORF23 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0828 (Fisher's exact test), Q value = 0.44

Table S545. Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
C9ORF23 MUTATED	6	0	3	0
C9ORF23 WILD-TYPE	67	43	76	45

'C9ORF23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.192 (Fisher's exact test), Q value = 0.59

Table S546. Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
C9ORF23 MUTATED	0	2	4
C9ORF23 WILD-TYPE	29	17	60

'C9ORF23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S547. Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
C9ORF23 MUTATED	2	2	2
C9ORF23 WILD-TYPE	31	46	29

'CUX1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S548. Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
CUX1 MUTATED	1	2	1	1
CUX1 WILD-TYPE	11	16	10	9

'CUX1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.654 (Fisher's exact test), Q value = 0.96

Table S549. Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
CUX1 MUTATED	2	0	1	1	1
CUX1 WILD-TYPE	10	10	6	6	14

'CUX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0223 (Fisher's exact test), Q value = 0.23

Table S550. Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CUX1 MUTATED	0	19	0	0	2
CUX1 WILD-TYPE	56	133	11	5	16

Figure S143. Get High-res Image Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CUX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.6

Table S551. Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CUX1 MUTATED	3	1	7
CUX1 WILD-TYPE	40	38	46

'CUX1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 0.53

Table S552. Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CUX1 MUTATED	10	4	3
CUX1 WILD-TYPE	61	68	57

'CUX1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S553. Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CUX1 MUTATED	5	6	4	2
CUX1 WILD-TYPE	63	72	27	24

'CUX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.255 (Fisher's exact test), Q value = 0.67

Table S554. Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CUX1 MUTATED	7	10	4
CUX1 WILD-TYPE	72	75	79

'CUX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00258 (Fisher's exact test), Q value = 0.056

Table S555. Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CUX1 MUTATED	1	1	2	7	7	2	1
CUX1 WILD-TYPE	43	40	15	26	28	29	45

Figure S144. Get High-res Image Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CUX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 0.75

Table S556. Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CUX1 MUTATED	5	9	5
CUX1 WILD-TYPE	64	70	87

'CUX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.167 (Fisher's exact test), Q value = 0.58

Table S557. Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CUX1 MUTATED	10	1	5	3
CUX1 WILD-TYPE	63	42	74	42

'CUX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.704 (Fisher's exact test), Q value = 0.98

Table S558. Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CUX1 MUTATED	3	2	4
CUX1 WILD-TYPE	26	17	60

'CUX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.415 (Fisher's exact test), Q value = 0.79

Table S559. Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CUX1 MUTATED	4	2	3
CUX1 WILD-TYPE	29	46	28

'CDK17 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0451 (Fisher's exact test), Q value = 0.33

Table S560. Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
CDK17 MUTATED	3	0	2	0
CDK17 WILD-TYPE	9	18	9	10

Figure S145. Get High-res Image Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'CDK17 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00211 (Fisher's exact test), Q value = 0.05

Table S561. Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
CDK17 MUTATED	0	0	3	2	0
CDK17 WILD-TYPE	12	10	4	5	15

Figure S146. Get High-res Image Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'CDK17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.59

Table S562. Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CDK17 MUTATED	1	10	0	0	3
CDK17 WILD-TYPE	55	142	11	5	15

'CDK17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0599 (Fisher's exact test), Q value = 0.38

Table S563. Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CDK17 MUTATED	0	1	5
CDK17 WILD-TYPE	43	38	48

'CDK17 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.683 (Fisher's exact test), Q value = 0.97

Table S564. Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CDK17 MUTATED	4	5	2
CDK17 WILD-TYPE	67	67	58

'CDK17 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.97 (Fisher's exact test), Q value = 1

Table S565. Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CDK17 MUTATED	4	5	1	1
CDK17 WILD-TYPE	64	73	30	25

'CDK17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.943 (Fisher's exact test), Q value = 1

Table S566. Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CDK17 MUTATED	5	5	4
CDK17 WILD-TYPE	74	80	79

'CDK17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0291 (Fisher's exact test), Q value = 0.27

Table S567. Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CDK17 MUTATED	1	1	2	5	2	3	0
CDK17 WILD-TYPE	43	40	15	28	33	28	46

Figure S147. Get High-res Image Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CDK17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.424 (Fisher's exact test), Q value = 0.79

Table S568. Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CDK17 MUTATED	3	7	4
CDK17 WILD-TYPE	66	72	88

'CDK17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.604 (Fisher's exact test), Q value = 0.92

Table S569. Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CDK17 MUTATED	6	1	4	3
CDK17 WILD-TYPE	67	42	75	42

'CDK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.719 (Fisher's exact test), Q value = 0.99

Table S570. Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CDK17 MUTATED	2	0	4
CDK17 WILD-TYPE	27	19	60

'CDK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0265 (Fisher's exact test), Q value = 0.25

Table S571. Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CDK17 MUTATED	2	0	4
CDK17 WILD-TYPE	31	48	27

Figure S148. Get High-res Image Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'USP28 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 0.77

Table S572. Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
USP28 MUTATED	0	9	0	0	1
USP28 WILD-TYPE	56	143	11	5	17

'USP28 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.188 (Fisher's exact test), Q value = 0.59

Table S573. Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
USP28 MUTATED	1	0	4
USP28 WILD-TYPE	42	39	49

'USP28 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.479 (Fisher's exact test), Q value = 0.84

Table S574. Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
USP28 MUTATED	4	4	1
USP28 WILD-TYPE	67	68	59

'USP28 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.475 (Fisher's exact test), Q value = 0.83

Table S575. Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
USP28 MUTATED	2	3	3	1
USP28 WILD-TYPE	66	75	28	25

'USP28 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.308 (Fisher's exact test), Q value = 0.72

Table S576. Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
USP28 MUTATED	2	6	2
USP28 WILD-TYPE	77	79	81

'USP28 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00888 (Fisher's exact test), Q value = 0.13

Table S577. Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
USP28 MUTATED	0	0	1	4	3	2	0
USP28 WILD-TYPE	44	41	16	29	32	29	46

Figure S149. Get High-res Image Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'USP28 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S578. Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
USP28 MUTATED	3	3	4
USP28 WILD-TYPE	66	76	88

'USP28 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.176 (Fisher's exact test), Q value = 0.58

Table S579. Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
USP28 MUTATED	6	0	3	1
USP28 WILD-TYPE	67	43	76	44

'USP28 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.562 (Fisher's exact test), Q value = 0.89

Table S580. Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
USP28 MUTATED	0	1	2
USP28 WILD-TYPE	29	18	62

'USP28 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.183 (Fisher's exact test), Q value = 0.59

Table S581. Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
USP28 MUTATED	2	0	1
USP28 WILD-TYPE	31	48	30

'MSH6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 0.77

Table S582. Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
MSH6 MUTATED	2	1	0	0
MSH6 WILD-TYPE	10	17	11	10

'MSH6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.282 (Fisher's exact test), Q value = 0.7

Table S583. Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
MSH6 MUTATED	1	0	1	1	0
MSH6 WILD-TYPE	11	10	6	6	15

'MSH6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0718 (Fisher's exact test), Q value = 0.42

Table S584. Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MSH6 MUTATED	1	12	0	0	4
MSH6 WILD-TYPE	55	140	11	5	14

'MSH6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.628 (Fisher's exact test), Q value = 0.95

Table S585. Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MSH6 MUTATED	2	1	4
MSH6 WILD-TYPE	41	38	49

'MSH6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.946 (Fisher's exact test), Q value = 1

Table S586. Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MSH6 MUTATED	5	6	4
MSH6 WILD-TYPE	66	66	56

'MSH6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.519 (Fisher's exact test), Q value = 0.87

Table S587. Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MSH6 MUTATED	3	8	3	1
MSH6 WILD-TYPE	65	70	28	25

'MSH6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 0.75

Table S588. Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MSH6 MUTATED	7	7	3
MSH6 WILD-TYPE	72	78	80

'MSH6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00019 (Fisher's exact test), Q value = 0.0086

Table S589. Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MSH6 MUTATED	1	0	2	6	7	0	1
MSH6 WILD-TYPE	43	41	15	27	28	31	45

Figure S150. Get High-res Image Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MSH6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.492 (Fisher's exact test), Q value = 0.85

Table S590. Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MSH6 MUTATED	5	7	4
MSH6 WILD-TYPE	64	72	88

'MSH6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.139 (Fisher's exact test), Q value = 0.54

Table S591. Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MSH6 MUTATED	9	1	3	3
MSH6 WILD-TYPE	64	42	76	42

'MSH6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.183 (Fisher's exact test), Q value = 0.59

Table S592. Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MSH6 MUTATED	0	2	2
MSH6 WILD-TYPE	29	17	62

'MSH6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.686 (Fisher's exact test), Q value = 0.97

Table S593. Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MSH6 MUTATED	1	1	2
MSH6 WILD-TYPE	32	47	29

'WDR45 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.653 (Fisher's exact test), Q value = 0.96

Table S594. Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
WDR45 MUTATED	1	9	0	0	1
WDR45 WILD-TYPE	55	143	11	5	17

'WDR45 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.58 (Fisher's exact test), Q value = 0.9

Table S595. Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
WDR45 MUTATED	1	3	2
WDR45 WILD-TYPE	42	36	51

'WDR45 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S596. Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
WDR45 MUTATED	3	4	3
WDR45 WILD-TYPE	68	68	57

'WDR45 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.585 (Fisher's exact test), Q value = 0.91

Table S597. Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
WDR45 MUTATED	3	6	1	0
WDR45 WILD-TYPE	65	72	30	26

'WDR45 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.863 (Fisher's exact test), Q value = 1

Table S598. Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
WDR45 MUTATED	4	3	4
WDR45 WILD-TYPE	75	82	79

'WDR45 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.242 (Fisher's exact test), Q value = 0.66

Table S599. Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
WDR45 MUTATED	1	0	0	4	2	2	2
WDR45 WILD-TYPE	43	41	17	29	33	29	44

'WDR45 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.226 (Fisher's exact test), Q value = 0.64

Table S600. Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
WDR45 MUTATED	1	6	4
WDR45 WILD-TYPE	68	73	88

'WDR45 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 0.6

Table S601. Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
WDR45 MUTATED	6	0	4	1
WDR45 WILD-TYPE	67	43	75	44

'WDR45 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 0.59

Table S602. Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
WDR45 MUTATED	0	2	2
WDR45 WILD-TYPE	29	17	62

'WDR45 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.296 (Fisher's exact test), Q value = 0.71

Table S603. Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
WDR45 MUTATED	0	2	2
WDR45 WILD-TYPE	33	46	29

'C14ORF166B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.371 (Fisher's exact test), Q value = 0.77

Table S604. Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
C14ORF166B MUTATED	0	8	0	0	1
C14ORF166B WILD-TYPE	56	144	11	5	17

'C14ORF166B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0386 (Fisher's exact test), Q value = 0.31

Table S605. Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
C14ORF166B MUTATED	0	0	4
C14ORF166B WILD-TYPE	43	39	49

Figure S151. Get High-res Image Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'C14ORF166B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.568 (Fisher's exact test), Q value = 0.89

Table S606. Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
C14ORF166B MUTATED	4	2	1
C14ORF166B WILD-TYPE	67	70	59

'C14ORF166B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.738 (Fisher's exact test), Q value = 0.99

Table S607. Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
C14ORF166B MUTATED	2	2	2	1
C14ORF166B WILD-TYPE	66	76	29	25

'C14ORF166B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.912 (Fisher's exact test), Q value = 1

Table S608. Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
C14ORF166B MUTATED	2	4	3
C14ORF166B WILD-TYPE	77	81	80

'C14ORF166B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0225 (Fisher's exact test), Q value = 0.23

Table S609. Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
C14ORF166B MUTATED	0	0	0	3	4	0	2
C14ORF166B WILD-TYPE	44	41	17	30	31	31	44

Figure S152. Get High-res Image Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'C14ORF166B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.352 (Fisher's exact test), Q value = 0.77

Table S610. Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
C14ORF166B MUTATED	2	1	5
C14ORF166B WILD-TYPE	67	78	87

'C14ORF166B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.229 (Fisher's exact test), Q value = 0.64

Table S611. Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
C14ORF166B MUTATED	4	0	4	0
C14ORF166B WILD-TYPE	69	43	75	45

'C14ORF166B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.745 (Fisher's exact test), Q value = 1

Table S612. Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
C14ORF166B MUTATED	0	0	3
C14ORF166B WILD-TYPE	29	19	61

'C14ORF166B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.356 (Fisher's exact test), Q value = 0.77

Table S613. Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
C14ORF166B MUTATED	0	1	2
C14ORF166B WILD-TYPE	33	47	29

'ATM MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0118 (Fisher's exact test), Q value = 0.17

Table S614. Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ATM MUTATED	6	2	1	0
ATM WILD-TYPE	6	16	10	10

Figure S153. Get High-res Image Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'ATM MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00028 (Fisher's exact test), Q value = 0.011

Table S615. Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ATM MUTATED	2	0	2	5	0
ATM WILD-TYPE	10	10	5	2	15

Figure S154. Get High-res Image Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'ATM MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00561 (Fisher's exact test), Q value = 0.093

Table S616. Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ATM MUTATED	0	22	1	1	3
ATM WILD-TYPE	56	130	10	4	15

Figure S155. Get High-res Image Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ATM MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.692 (Fisher's exact test), Q value = 0.97

Table S617. Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ATM MUTATED	4	2	6
ATM WILD-TYPE	39	37	47

'ATM MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.831 (Fisher's exact test), Q value = 1

Table S618. Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ATM MUTATED	9	10	6
ATM WILD-TYPE	62	62	54

'ATM MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.535 (Fisher's exact test), Q value = 0.88

Table S619. Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ATM MUTATED	9	10	5	1
ATM WILD-TYPE	59	68	26	25

'ATM MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.706 (Fisher's exact test), Q value = 0.98

Table S620. Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ATM MUTATED	11	10	8
ATM WILD-TYPE	68	75	75

'ATM MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00054 (Fisher's exact test), Q value = 0.018

Table S621. Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ATM MUTATED	1	2	3	8	10	3	2
ATM WILD-TYPE	43	39	14	25	25	28	44

Figure S156. Get High-res Image Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ATM MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.533 (Fisher's exact test), Q value = 0.88

Table S622. Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ATM MUTATED	7	12	9
ATM WILD-TYPE	62	67	83

'ATM MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.312 (Fisher's exact test), Q value = 0.72

Table S623. Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ATM MUTATED	12	2	9	5
ATM WILD-TYPE	61	41	70	40

'ATM MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.172 (Fisher's exact test), Q value = 0.58

Table S624. Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ATM MUTATED	5	3	4
ATM WILD-TYPE	24	16	60

'ATM MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.127 (Fisher's exact test), Q value = 0.53

Table S625. Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ATM MUTATED	5	2	5
ATM WILD-TYPE	28	46	26

'RAE1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.455 (Fisher's exact test), Q value = 0.81

Table S626. Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
RAE1 MUTATED	1	3	0	0
RAE1 WILD-TYPE	11	15	11	10

'RAE1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0777 (Fisher's exact test), Q value = 0.43

Table S627. Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
RAE1 MUTATED	3	0	1	0	0
RAE1 WILD-TYPE	9	10	6	7	15

'RAE1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.461 (Fisher's exact test), Q value = 0.82

Table S628. Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
RAE1 MUTATED	1	8	0	0	2
RAE1 WILD-TYPE	55	144	11	5	16

'RAE1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.188 (Fisher's exact test), Q value = 0.59

Table S629. Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
RAE1 MUTATED	1	0	4
RAE1 WILD-TYPE	42	39	49

'RAE1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0391 (Fisher's exact test), Q value = 0.31

Table S630. Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
RAE1 MUTATED	7	1	1
RAE1 WILD-TYPE	64	71	59

Figure S157. Get High-res Image Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'RAE1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.677 (Fisher's exact test), Q value = 0.97

Table S631. Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
RAE1 MUTATED	4	2	2	1
RAE1 WILD-TYPE	64	76	29	25

'RAE1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 0.83

Table S632. Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
RAE1 MUTATED	5	4	2
RAE1 WILD-TYPE	74	81	81

'RAE1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.018 (Fisher's exact test), Q value = 0.21

Table S633. Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
RAE1 MUTATED	1	0	1	4	4	1	0
RAE1 WILD-TYPE	43	41	16	29	31	30	46

Figure S158. Get High-res Image Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RAE1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.509 (Fisher's exact test), Q value = 0.86

Table S634. Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
RAE1 MUTATED	4	4	2
RAE1 WILD-TYPE	65	75	90

'RAE1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.413 (Fisher's exact test), Q value = 0.79

Table S635. Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
RAE1 MUTATED	5	0	3	2
RAE1 WILD-TYPE	68	43	76	43

'RAE1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.228 (Fisher's exact test), Q value = 0.64

Table S636. Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
RAE1 MUTATED	3	0	2
RAE1 WILD-TYPE	26	19	62

'RAE1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.603 (Fisher's exact test), Q value = 0.92

Table S637. Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
RAE1 MUTATED	2	1	2
RAE1 WILD-TYPE	31	47	29

'ZNF485 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S638. Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ZNF485 MUTATED	1	1	1	0
ZNF485 WILD-TYPE	11	17	10	10

'ZNF485 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.078 (Fisher's exact test), Q value = 0.43

Table S639. Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ZNF485 MUTATED	1	0	2	0	0
ZNF485 WILD-TYPE	11	10	5	7	15

'ZNF485 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.359 (Fisher's exact test), Q value = 0.77

Table S640. Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF485 MUTATED	0	9	0	0	0
ZNF485 WILD-TYPE	56	143	11	5	18

'ZNF485 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S641. Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF485 MUTATED	1	1	2
ZNF485 WILD-TYPE	42	38	51

'ZNF485 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S642. Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF485 MUTATED	3	3	2
ZNF485 WILD-TYPE	68	69	58

'ZNF485 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.313 (Fisher's exact test), Q value = 0.72

Table S643. Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF485 MUTATED	1	3	2	2
ZNF485 WILD-TYPE	67	75	29	24

'ZNF485 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.642 (Fisher's exact test), Q value = 0.95

Table S644. Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF485 MUTATED	4	3	2
ZNF485 WILD-TYPE	75	82	81

'ZNF485 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.414 (Fisher's exact test), Q value = 0.79

Table S645. Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF485 MUTATED	1	0	1	2	3	1	1
ZNF485 WILD-TYPE	43	41	16	31	32	30	45

'ZNF485 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.127 (Fisher's exact test), Q value = 0.53

Table S646. Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF485 MUTATED	1	6	2
ZNF485 WILD-TYPE	68	73	90

'ZNF485 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.294 (Fisher's exact test), Q value = 0.7

Table S647. Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF485 MUTATED	5	1	1	2
ZNF485 WILD-TYPE	68	42	78	43

'POLE MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.735 (Fisher's exact test), Q value = 0.99

Table S648. Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
POLE MUTATED	2	3	1	0
POLE WILD-TYPE	10	15	10	10

'POLE MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0608 (Fisher's exact test), Q value = 0.38

Table S649. Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
POLE MUTATED	3	0	2	1	0
POLE WILD-TYPE	9	10	5	6	15

'POLE MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0383 (Fisher's exact test), Q value = 0.31

Table S650. Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
POLE MUTATED	1	23	0	0	2
POLE WILD-TYPE	55	129	11	5	16

Figure S159. Get High-res Image Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'POLE MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.252 (Fisher's exact test), Q value = 0.67

Table S651. Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
POLE MUTATED	2	6	6
POLE WILD-TYPE	41	33	47

'POLE MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S652. Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
POLE MUTATED	8	9	6
POLE WILD-TYPE	63	63	54

'POLE MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.729 (Fisher's exact test), Q value = 0.99

Table S653. Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
POLE MUTATED	6	9	5	3
POLE WILD-TYPE	62	69	26	23

'POLE MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S654. Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
POLE MUTATED	9	10	8
POLE WILD-TYPE	70	75	75

'POLE MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0132 (Fisher's exact test), Q value = 0.18

Table S655. Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
POLE MUTATED	2	1	1	8	8	3	4
POLE WILD-TYPE	42	40	16	25	27	28	42

Figure S160. Get High-res Image Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'POLE MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.608 (Fisher's exact test), Q value = 0.93

Table S656. Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
POLE MUTATED	6	11	9
POLE WILD-TYPE	63	68	83

'POLE MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.151 (Fisher's exact test), Q value = 0.56

Table S657. Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
POLE MUTATED	13	2	7	4
POLE WILD-TYPE	60	41	72	41

'POLE MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 0.59

Table S658. Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
POLE MUTATED	2	4	4
POLE WILD-TYPE	27	15	60

'POLE MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.536 (Fisher's exact test), Q value = 0.88

Table S659. Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
POLE MUTATED	3	3	4
POLE WILD-TYPE	30	45	27

'AHCYL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.424 (Fisher's exact test), Q value = 0.79

Table S660. Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
AHCYL1 MUTATED	0	5	0	0	1
AHCYL1 WILD-TYPE	56	147	11	5	17

'AHCYL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S661. Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
AHCYL1 MUTATED	1	1	1
AHCYL1 WILD-TYPE	42	38	52

'AHCYL1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 0.95

Table S662. Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
AHCYL1 MUTATED	1	3	1
AHCYL1 WILD-TYPE	70	69	59

'AHCYL1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.734 (Fisher's exact test), Q value = 0.99

Table S663. Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
AHCYL1 MUTATED	1	3	1	0
AHCYL1 WILD-TYPE	67	75	30	26

'AHCYL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S664. Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
AHCYL1 MUTATED	2	2	2
AHCYL1 WILD-TYPE	77	83	81

'AHCYL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0121 (Fisher's exact test), Q value = 0.17

Table S665. Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
AHCYL1 MUTATED	0	0	0	4	1	1	0
AHCYL1 WILD-TYPE	44	41	17	29	34	30	46

Figure S161. Get High-res Image Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'AHCYL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.679 (Fisher's exact test), Q value = 0.97

Table S666. Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
AHCYL1 MUTATED	1	3	2
AHCYL1 WILD-TYPE	68	76	90

'AHCYL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S667. Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
AHCYL1 MUTATED	2	1	3	0
AHCYL1 WILD-TYPE	71	42	76	45

'ZNF334 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S668. Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ZNF334 MUTATED	1	1	1	0
ZNF334 WILD-TYPE	11	17	10	10

'ZNF334 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0789 (Fisher's exact test), Q value = 0.43

Table S669. Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ZNF334 MUTATED	1	0	2	0	0
ZNF334 WILD-TYPE	11	10	5	7	15

'ZNF334 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.304 (Fisher's exact test), Q value = 0.72

Table S670. Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF334 MUTATED	1	13	0	0	2
ZNF334 WILD-TYPE	55	139	11	5	16

'ZNF334 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.373 (Fisher's exact test), Q value = 0.77

Table S671. Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF334 MUTATED	4	1	6
ZNF334 WILD-TYPE	39	38	47

'ZNF334 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 0.89

Table S672. Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF334 MUTATED	5	7	3
ZNF334 WILD-TYPE	66	65	57

'ZNF334 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.65 (Fisher's exact test), Q value = 0.96

Table S673. Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF334 MUTATED	3	7	3	2
ZNF334 WILD-TYPE	65	71	28	24

'ZNF334 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.398 (Fisher's exact test), Q value = 0.77

Table S674. Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF334 MUTATED	8	4	5
ZNF334 WILD-TYPE	71	81	78

'ZNF334 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0126 (Fisher's exact test), Q value = 0.17

Table S675. Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF334 MUTATED	1	0	2	5	5	3	1
ZNF334 WILD-TYPE	43	41	15	28	30	28	45

Figure S162. Get High-res Image Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF334 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.948 (Fisher's exact test), Q value = 1

Table S676. Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF334 MUTATED	4	6	6
ZNF334 WILD-TYPE	65	73	86

'ZNF334 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.55 (Fisher's exact test), Q value = 0.89

Table S677. Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF334 MUTATED	7	1	5	3
ZNF334 WILD-TYPE	66	42	74	42

'ZNF334 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S678. Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZNF334 MUTATED	2	2	4
ZNF334 WILD-TYPE	27	17	60

'ZNF334 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.532 (Fisher's exact test), Q value = 0.88

Table S679. Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZNF334 MUTATED	3	2	3
ZNF334 WILD-TYPE	30	46	28

'SACS MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0206 (Fisher's exact test), Q value = 0.22

Table S680. Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
SACS MUTATED	6	3	1	0
SACS WILD-TYPE	6	15	10	10

Figure S163. Get High-res Image Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'SACS MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00156 (Fisher's exact test), Q value = 0.04

Table S681. Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
SACS MUTATED	2	1	2	5	0
SACS WILD-TYPE	10	9	5	2	15

Figure S164. Get High-res Image Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'SACS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0344 (Fisher's exact test), Q value = 0.3

Table S682. Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SACS MUTATED	1	22	0	0	3
SACS WILD-TYPE	55	130	11	5	15

Figure S165. Get High-res Image Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'SACS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.686 (Fisher's exact test), Q value = 0.97

Table S683. Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SACS MUTATED	2	2	5
SACS WILD-TYPE	41	37	48

'SACS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.57 (Fisher's exact test), Q value = 0.89

Table S684. Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SACS MUTATED	9	8	4
SACS WILD-TYPE	62	64	56

'SACS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S685. Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SACS MUTATED	8	9	3	1
SACS WILD-TYPE	60	69	28	25

'SACS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.221 (Fisher's exact test), Q value = 0.63

Table S686. Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SACS MUTATED	7	13	6
SACS WILD-TYPE	72	72	77

'SACS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00168 (Fisher's exact test), Q value = 0.042

Table S687. Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SACS MUTATED	1	2	3	9	7	1	3
SACS WILD-TYPE	43	39	14	24	28	30	43

Figure S166. Get High-res Image Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SACS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.211 (Fisher's exact test), Q value = 0.61

Table S688. Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SACS MUTATED	5	12	7
SACS WILD-TYPE	64	67	85

'SACS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0888 (Fisher's exact test), Q value = 0.46

Table S689. Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SACS MUTATED	13	2	6	3
SACS WILD-TYPE	60	41	73	42

'SACS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S690. Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
SACS MUTATED	2	2	4
SACS WILD-TYPE	27	17	60

'SACS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 0.7

Table S691. Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
SACS MUTATED	1	3	4
SACS WILD-TYPE	32	45	27

'MSH4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 0.97

Table S692. Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
MSH4 MUTATED	2	1	1	0
MSH4 WILD-TYPE	10	17	10	10

'MSH4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0925 (Fisher's exact test), Q value = 0.46

Table S693. Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
MSH4 MUTATED	1	0	2	1	0
MSH4 WILD-TYPE	11	10	5	6	15

'MSH4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.091 (Fisher's exact test), Q value = 0.46

Table S694. Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MSH4 MUTATED	0	13	0	0	2
MSH4 WILD-TYPE	56	139	11	5	16

'MSH4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S695. Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MSH4 MUTATED	2	1	3
MSH4 WILD-TYPE	41	38	50

'MSH4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.482 (Fisher's exact test), Q value = 0.84

Table S696. Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MSH4 MUTATED	6	5	2
MSH4 WILD-TYPE	65	67	58

'MSH4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.952 (Fisher's exact test), Q value = 1

Table S697. Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MSH4 MUTATED	4	6	2	1
MSH4 WILD-TYPE	64	72	29	25

'MSH4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.845 (Fisher's exact test), Q value = 1

Table S698. Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MSH4 MUTATED	5	6	4
MSH4 WILD-TYPE	74	79	79

'MSH4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0288 (Fisher's exact test), Q value = 0.27

Table S699. Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MSH4 MUTATED	0	1	1	5	5	1	2
MSH4 WILD-TYPE	44	40	16	28	30	30	44

Figure S167. Get High-res Image Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MSH4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 0.79

Table S700. Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MSH4 MUTATED	3	7	4
MSH4 WILD-TYPE	66	72	88

'MSH4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0847 (Fisher's exact test), Q value = 0.44

Table S701. Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MSH4 MUTATED	8	2	4	0
MSH4 WILD-TYPE	65	41	75	45

'MSH4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.187 (Fisher's exact test), Q value = 0.59

Table S702. Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MSH4 MUTATED	0	2	2
MSH4 WILD-TYPE	29	17	62

'MSH4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.689 (Fisher's exact test), Q value = 0.97

Table S703. Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MSH4 MUTATED	1	1	2
MSH4 WILD-TYPE	32	47	29

'SLC26A8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 0.55

Table S704. Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SLC26A8 MUTATED	0	10	0	0	2
SLC26A8 WILD-TYPE	56	142	11	5	16

'SLC26A8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.633 (Fisher's exact test), Q value = 0.95

Table S705. Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SLC26A8 MUTATED	2	1	4
SLC26A8 WILD-TYPE	41	38	49

'SLC26A8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 0.97

Table S706. Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SLC26A8 MUTATED	4	5	2
SLC26A8 WILD-TYPE	67	67	58

'SLC26A8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.439 (Fisher's exact test), Q value = 0.8

Table S707. Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SLC26A8 MUTATED	3	5	3	0
SLC26A8 WILD-TYPE	65	73	28	26

'SLC26A8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.297 (Fisher's exact test), Q value = 0.71

Table S708. Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SLC26A8 MUTATED	6	4	2
SLC26A8 WILD-TYPE	73	81	81

'SLC26A8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00064 (Fisher's exact test), Q value = 0.02

Table S709. Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SLC26A8 MUTATED	0	0	1	4	6	0	1
SLC26A8 WILD-TYPE	44	41	16	29	29	31	45

Figure S168. Get High-res Image Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SLC26A8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 0.65

Table S710. Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SLC26A8 MUTATED	4	6	2
SLC26A8 WILD-TYPE	65	73	90

'SLC26A8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.541 (Fisher's exact test), Q value = 0.88

Table S711. Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SLC26A8 MUTATED	6	1	3	2
SLC26A8 WILD-TYPE	67	42	76	43

'SLC26A8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.361 (Fisher's exact test), Q value = 0.77

Table S712. Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
SLC26A8 MUTATED	1	2	2
SLC26A8 WILD-TYPE	28	17	62

'SLC26A8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.602 (Fisher's exact test), Q value = 0.92

Table S713. Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
SLC26A8 MUTATED	2	1	2
SLC26A8 WILD-TYPE	31	47	29

'KIF20B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.29 (Fisher's exact test), Q value = 0.7

Table S714. Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
KIF20B MUTATED	3	1	1	0
KIF20B WILD-TYPE	9	17	10	10

'KIF20B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0431 (Fisher's exact test), Q value = 0.32

Table S715. Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
KIF20B MUTATED	1	0	2	2	0
KIF20B WILD-TYPE	11	10	5	5	15

Figure S169. Get High-res Image Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'KIF20B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0222 (Fisher's exact test), Q value = 0.23

Table S716. Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
KIF20B MUTATED	0	19	0	0	2
KIF20B WILD-TYPE	56	133	11	5	16

Figure S170. Get High-res Image Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'KIF20B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.803 (Fisher's exact test), Q value = 1

Table S717. Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
KIF20B MUTATED	3	3	6
KIF20B WILD-TYPE	40	36	47

'KIF20B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.318 (Fisher's exact test), Q value = 0.73

Table S718. Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
KIF20B MUTATED	6	9	3
KIF20B WILD-TYPE	65	63	57

'KIF20B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.419 (Fisher's exact test), Q value = 0.79

Table S719. Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
KIF20B MUTATED	4	7	5	2
KIF20B WILD-TYPE	64	71	26	24

'KIF20B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.579 (Fisher's exact test), Q value = 0.9

Table S720. Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
KIF20B MUTATED	7	9	5
KIF20B WILD-TYPE	72	76	78

'KIF20B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00015 (Fisher's exact test), Q value = 0.0072

Table S721. Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
KIF20B MUTATED	0	1	1	8	7	3	1
KIF20B WILD-TYPE	44	40	16	25	28	28	45

Figure S171. Get High-res Image Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'KIF20B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.488 (Fisher's exact test), Q value = 0.85

Table S722. Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
KIF20B MUTATED	5	9	6
KIF20B WILD-TYPE	64	70	86

'KIF20B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0482 (Fisher's exact test), Q value = 0.33

Table S723. Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
KIF20B MUTATED	12	2	4	2
KIF20B WILD-TYPE	61	41	75	43

Figure S172. Get High-res Image Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'KIF20B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.272 (Fisher's exact test), Q value = 0.7

Table S724. Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
KIF20B MUTATED	1	3	4
KIF20B WILD-TYPE	28	16	60

'KIF20B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.327 (Fisher's exact test), Q value = 0.74

Table S725. Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
KIF20B MUTATED	2	2	4
KIF20B WILD-TYPE	31	46	27

'RRAS2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0982 (Fisher's exact test), Q value = 0.47

Table S726. Gene #66: 'RRAS2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
RRAS2 MUTATED	0	2	0	0	2
RRAS2 WILD-TYPE	56	150	11	5	16

'RRAS2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S727. Gene #66: 'RRAS2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
RRAS2 MUTATED	2	1	1
RRAS2 WILD-TYPE	69	71	59

'RRAS2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.203 (Fisher's exact test), Q value = 0.6

Table S728. Gene #66: 'RRAS2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
RRAS2 MUTATED	3	0	1	0
RRAS2 WILD-TYPE	65	78	30	26

'RRAS2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.172 (Fisher's exact test), Q value = 0.58

Table S729. Gene #66: 'RRAS2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
RRAS2 MUTATED	1	0	3
RRAS2 WILD-TYPE	78	85	80

'RRAS2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.213 (Fisher's exact test), Q value = 0.61

Table S730. Gene #66: 'RRAS2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
RRAS2 MUTATED	0	0	1	0	1	0	2
RRAS2 WILD-TYPE	44	41	16	33	34	31	44

'RRAS2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.391 (Fisher's exact test), Q value = 0.77

Table S731. Gene #66: 'RRAS2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
RRAS2 MUTATED	2	0	2
RRAS2 WILD-TYPE	67	79	90

'RRAS2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.918 (Fisher's exact test), Q value = 1

Table S732. Gene #66: 'RRAS2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
RRAS2 MUTATED	1	0	2	1
RRAS2 WILD-TYPE	72	43	77	44

'CTNND1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.287 (Fisher's exact test), Q value = 0.7

Table S733. Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
CTNND1 MUTATED	3	1	1	0
CTNND1 WILD-TYPE	9	17	10	10

'CTNND1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.399 (Fisher's exact test), Q value = 0.77

Table S734. Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
CTNND1 MUTATED	1	0	2	1	1
CTNND1 WILD-TYPE	11	10	5	6	14

'CTNND1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.136 (Fisher's exact test), Q value = 0.53

Table S735. Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CTNND1 MUTATED	1	15	0	0	3
CTNND1 WILD-TYPE	55	137	11	5	15

'CTNND1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S736. Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CTNND1 MUTATED	3	2	4
CTNND1 WILD-TYPE	40	37	49

'CTNND1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.95 (Fisher's exact test), Q value = 1

Table S737. Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CTNND1 MUTATED	5	7	5
CTNND1 WILD-TYPE	66	65	55

'CTNND1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.174 (Fisher's exact test), Q value = 0.58

Table S738. Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CTNND1 MUTATED	4	10	3	0
CTNND1 WILD-TYPE	64	68	28	26

'CTNND1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.601 (Fisher's exact test), Q value = 0.92

Table S739. Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CTNND1 MUTATED	8	5	6
CTNND1 WILD-TYPE	71	80	77

'CTNND1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0404 (Fisher's exact test), Q value = 0.31

Table S740. Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CTNND1 MUTATED	1	1	1	3	8	2	3
CTNND1 WILD-TYPE	43	40	16	30	27	29	43

Figure S173. Get High-res Image Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CTNND1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.911 (Fisher's exact test), Q value = 1

Table S741. Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CTNND1 MUTATED	6	5	7
CTNND1 WILD-TYPE	63	74	85

'CTNND1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.236 (Fisher's exact test), Q value = 0.65

Table S742. Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CTNND1 MUTATED	9	1	6	2
CTNND1 WILD-TYPE	64	42	73	43

'CTNND1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.232 (Fisher's exact test), Q value = 0.64

Table S743. Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CTNND1 MUTATED	2	3	3
CTNND1 WILD-TYPE	27	16	61

'CTNND1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.534 (Fisher's exact test), Q value = 0.88

Table S744. Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CTNND1 MUTATED	3	2	3
CTNND1 WILD-TYPE	30	46	28

'NFE2L3 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S745. Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
NFE2L3 MUTATED	3	8	0	0	1
NFE2L3 WILD-TYPE	53	144	11	5	17

'NFE2L3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.033 (Fisher's exact test), Q value = 0.29

Table S746. Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
NFE2L3 MUTATED	6	0	3
NFE2L3 WILD-TYPE	37	39	50

Figure S174. Get High-res Image Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'NFE2L3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S747. Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
NFE2L3 MUTATED	3	3	4
NFE2L3 WILD-TYPE	68	69	56

'NFE2L3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.298 (Fisher's exact test), Q value = 0.71

Table S748. Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
NFE2L3 MUTATED	1	6	2	1
NFE2L3 WILD-TYPE	67	72	29	25

'NFE2L3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0469 (Fisher's exact test), Q value = 0.33

Table S749. Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
NFE2L3 MUTATED	8	2	2
NFE2L3 WILD-TYPE	71	83	81

Figure S175. Get High-res Image Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'NFE2L3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0191 (Fisher's exact test), Q value = 0.21

Table S750. Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
NFE2L3 MUTATED	2	0	3	4	2	0	1
NFE2L3 WILD-TYPE	42	41	14	29	33	31	45

Figure S176. Get High-res Image Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NFE2L3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.462 (Fisher's exact test), Q value = 0.82

Table S751. Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
NFE2L3 MUTATED	5	3	3
NFE2L3 WILD-TYPE	64	76	89

'NFE2L3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.31 (Fisher's exact test), Q value = 0.72

Table S752. Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
NFE2L3 MUTATED	5	0	3	3
NFE2L3 WILD-TYPE	68	43	76	42

'NFE2L3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.216 (Fisher's exact test), Q value = 0.62

Table S753. Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
NFE2L3 MUTATED	3	2	2
NFE2L3 WILD-TYPE	26	17	62

'NFE2L3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.226 (Fisher's exact test), Q value = 0.64

Table S754. Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
NFE2L3 MUTATED	4	1	2
NFE2L3 WILD-TYPE	29	47	29

'FAM65B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0433 (Fisher's exact test), Q value = 0.32

Table S755. Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
FAM65B MUTATED	0	13	0	0	3
FAM65B WILD-TYPE	56	139	11	5	15

Figure S177. Get High-res Image Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'FAM65B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.328 (Fisher's exact test), Q value = 0.74

Table S756. Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
FAM65B MUTATED	3	1	6
FAM65B WILD-TYPE	40	38	47

'FAM65B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.481 (Fisher's exact test), Q value = 0.84

Table S757. Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
FAM65B MUTATED	6	5	2
FAM65B WILD-TYPE	65	67	58

'FAM65B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.447 (Fisher's exact test), Q value = 0.81

Table S758. Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
FAM65B MUTATED	3	5	4	1
FAM65B WILD-TYPE	65	73	27	25

'FAM65B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 0.9

Table S759. Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
FAM65B MUTATED	7	5	4
FAM65B WILD-TYPE	72	80	79

'FAM65B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00722 (Fisher's exact test), Q value = 0.11

Table S760. Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
FAM65B MUTATED	0	1	2	4	6	0	3
FAM65B WILD-TYPE	44	40	15	29	29	31	43

Figure S178. Get High-res Image Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FAM65B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.943 (Fisher's exact test), Q value = 1

Table S761. Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
FAM65B MUTATED	5	5	5
FAM65B WILD-TYPE	64	74	87

'FAM65B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.111 (Fisher's exact test), Q value = 0.51

Table S762. Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
FAM65B MUTATED	8	0	5	2
FAM65B WILD-TYPE	65	43	74	43

'FAM65B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.602 (Fisher's exact test), Q value = 0.92

Table S763. Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
FAM65B MUTATED	1	2	5
FAM65B WILD-TYPE	28	17	59

'FAM65B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.328 (Fisher's exact test), Q value = 0.74

Table S764. Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
FAM65B MUTATED	2	2	4
FAM65B WILD-TYPE	31	46	27

'RNF43 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 0.53

Table S765. Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
RNF43 MUTATED	3	1	0	0
RNF43 WILD-TYPE	9	17	11	10

'RNF43 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00961 (Fisher's exact test), Q value = 0.14

Table S766. Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
RNF43 MUTATED	1	0	0	3	0
RNF43 WILD-TYPE	11	10	7	4	15

Figure S179. Get High-res Image Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'RNF43 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 0.55

Table S767. Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
RNF43 MUTATED	0	10	0	0	2
RNF43 WILD-TYPE	56	142	11	5	16

'RNF43 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.447 (Fisher's exact test), Q value = 0.81

Table S768. Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
RNF43 MUTATED	2	0	3
RNF43 WILD-TYPE	41	39	50

'RNF43 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.297 (Fisher's exact test), Q value = 0.71

Table S769. Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
RNF43 MUTATED	3	7	2
RNF43 WILD-TYPE	68	65	58

'RNF43 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.494 (Fisher's exact test), Q value = 0.85

Table S770. Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
RNF43 MUTATED	6	5	1	0
RNF43 WILD-TYPE	62	73	30	26

'RNF43 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0426 (Fisher's exact test), Q value = 0.32

Table S771. Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
RNF43 MUTATED	3	8	1
RNF43 WILD-TYPE	76	77	82

Figure S180. Get High-res Image Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'RNF43 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 5e-05 (Fisher's exact test), Q value = 0.0031

Table S772. Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
RNF43 MUTATED	0	1	1	8	1	1	0
RNF43 WILD-TYPE	44	40	16	25	34	30	46

Figure S181. Get High-res Image Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RNF43 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0653 (Fisher's exact test), Q value = 0.39

Table S773. Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
RNF43 MUTATED	2	8	2
RNF43 WILD-TYPE	67	71	90

'RNF43 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0124 (Fisher's exact test), Q value = 0.17

Table S774. Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
RNF43 MUTATED	9	1	1	1
RNF43 WILD-TYPE	64	42	78	44

Figure S182. Get High-res Image Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'RNF43 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.183 (Fisher's exact test), Q value = 0.59

Table S775. Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
RNF43 MUTATED	0	2	2
RNF43 WILD-TYPE	29	17	62

'RNF43 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0362 (Fisher's exact test), Q value = 0.3

Table S776. Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
RNF43 MUTATED	1	0	3
RNF43 WILD-TYPE	32	48	28

Figure S183. Get High-res Image Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MRPL47 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 0.97

Table S777. Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
MRPL47 MUTATED	1	2	0	0
MRPL47 WILD-TYPE	11	16	11	10

'MRPL47 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.532 (Fisher's exact test), Q value = 0.88

Table S778. Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
MRPL47 MUTATED	1	1	1	0	0
MRPL47 WILD-TYPE	11	9	6	7	15

'MRPL47 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S779. Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MRPL47 MUTATED	1	5	0	0	0
MRPL47 WILD-TYPE	55	147	11	5	18

'MRPL47 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S780. Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MRPL47 MUTATED	1	0	2
MRPL47 WILD-TYPE	42	39	51

'MRPL47 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S781. Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MRPL47 MUTATED	2	2	2
MRPL47 WILD-TYPE	69	70	58

'MRPL47 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.505 (Fisher's exact test), Q value = 0.86

Table S782. Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MRPL47 MUTATED	1	4	0	1
MRPL47 WILD-TYPE	67	74	31	25

'MRPL47 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.527 (Fisher's exact test), Q value = 0.87

Table S783. Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MRPL47 MUTATED	3	2	1
MRPL47 WILD-TYPE	76	83	82

'MRPL47 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0735 (Fisher's exact test), Q value = 0.42

Table S784. Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MRPL47 MUTATED	1	0	1	3	1	0	0
MRPL47 WILD-TYPE	43	41	16	30	34	31	46

'MRPL47 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S785. Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MRPL47 MUTATED	1	1	2
MRPL47 WILD-TYPE	68	78	90

'MRPL47 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.702 (Fisher's exact test), Q value = 0.98

Table S786. Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MRPL47 MUTATED	2	1	1	0
MRPL47 WILD-TYPE	71	42	78	45

'TIGD4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S787. Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
TIGD4 MUTATED	1	2	1	0
TIGD4 WILD-TYPE	11	16	10	10

'TIGD4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.583 (Fisher's exact test), Q value = 0.91

Table S788. Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
TIGD4 MUTATED	2	0	1	0	1
TIGD4 WILD-TYPE	10	10	6	7	14

'TIGD4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 0.81

Table S789. Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
TIGD4 MUTATED	1	10	0	0	2
TIGD4 WILD-TYPE	55	142	11	5	16

'TIGD4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S790. Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
TIGD4 MUTATED	2	1	3
TIGD4 WILD-TYPE	41	38	50

'TIGD4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 0.98

Table S791. Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
TIGD4 MUTATED	5	5	2
TIGD4 WILD-TYPE	66	67	58

'TIGD4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.078 (Fisher's exact test), Q value = 0.43

Table S792. Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
TIGD4 MUTATED	3	4	5	0
TIGD4 WILD-TYPE	65	74	26	26

'TIGD4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.332 (Fisher's exact test), Q value = 0.74

Table S793. Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
TIGD4 MUTATED	6	5	2
TIGD4 WILD-TYPE	73	80	81

'TIGD4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00168 (Fisher's exact test), Q value = 0.042

Table S794. Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
TIGD4 MUTATED	0	0	1	4	6	0	2
TIGD4 WILD-TYPE	44	41	16	29	29	31	44

Figure S184. Get High-res Image Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TIGD4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.149 (Fisher's exact test), Q value = 0.55

Table S795. Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
TIGD4 MUTATED	3	7	2
TIGD4 WILD-TYPE	66	72	90

'TIGD4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.539 (Fisher's exact test), Q value = 0.88

Table S796. Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
TIGD4 MUTATED	6	1	3	2
TIGD4 WILD-TYPE	67	42	76	43

'TIGD4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 0.58

Table S797. Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
TIGD4 MUTATED	0	2	3
TIGD4 WILD-TYPE	29	17	61

'TIGD4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.6 (Fisher's exact test), Q value = 0.92

Table S798. Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
TIGD4 MUTATED	2	1	2
TIGD4 WILD-TYPE	31	47	29

'FILIP1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.535 (Fisher's exact test), Q value = 0.88

Table S799. Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
FILIP1 MUTATED	2	2	0	0
FILIP1 WILD-TYPE	10	16	11	10

'FILIP1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.246 (Fisher's exact test), Q value = 0.66

Table S800. Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
FILIP1 MUTATED	2	0	1	1	0
FILIP1 WILD-TYPE	10	10	6	6	15

'FILIP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.301 (Fisher's exact test), Q value = 0.71

Table S801. Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
FILIP1 MUTATED	1	13	0	0	2
FILIP1 WILD-TYPE	55	139	11	5	16

'FILIP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.388 (Fisher's exact test), Q value = 0.77

Table S802. Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
FILIP1 MUTATED	2	1	5
FILIP1 WILD-TYPE	41	38	48

'FILIP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.74 (Fisher's exact test), Q value = 0.99

Table S803. Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
FILIP1 MUTATED	5	6	3
FILIP1 WILD-TYPE	66	66	57

'FILIP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.117 (Fisher's exact test), Q value = 0.52

Table S804. Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
FILIP1 MUTATED	2	6	5	1
FILIP1 WILD-TYPE	66	72	26	25

'FILIP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.807 (Fisher's exact test), Q value = 1

Table S805. Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
FILIP1 MUTATED	6	6	4
FILIP1 WILD-TYPE	73	79	79

'FILIP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0025 (Fisher's exact test), Q value = 0.055

Table S806. Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
FILIP1 MUTATED	0	0	1	4	7	1	3
FILIP1 WILD-TYPE	44	41	16	29	28	30	43

Figure S185. Get High-res Image Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FILIP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.846 (Fisher's exact test), Q value = 1

Table S807. Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
FILIP1 MUTATED	4	6	5
FILIP1 WILD-TYPE	65	73	87

'FILIP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.119 (Fisher's exact test), Q value = 0.52

Table S808. Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
FILIP1 MUTATED	9	1	3	2
FILIP1 WILD-TYPE	64	42	76	43

'FILIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.567 (Fisher's exact test), Q value = 0.89

Table S809. Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
FILIP1 MUTATED	2	1	2
FILIP1 WILD-TYPE	27	18	62

'FILIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S810. Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
FILIP1 MUTATED	2	2	1
FILIP1 WILD-TYPE	31	46	30

'SLC1A3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 0.97

Table S811. Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SLC1A3 MUTATED	2	8	0	0	2
SLC1A3 WILD-TYPE	54	144	11	5	16

'SLC1A3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.668 (Fisher's exact test), Q value = 0.97

Table S812. Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SLC1A3 MUTATED	3	1	2
SLC1A3 WILD-TYPE	40	38	51

'SLC1A3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S813. Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SLC1A3 MUTATED	3	3	4
SLC1A3 WILD-TYPE	68	69	56

'SLC1A3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.398 (Fisher's exact test), Q value = 0.77

Table S814. Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SLC1A3 MUTATED	2	6	2	0
SLC1A3 WILD-TYPE	66	72	29	26

'SLC1A3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.154 (Fisher's exact test), Q value = 0.56

Table S815. Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SLC1A3 MUTATED	7	2	3
SLC1A3 WILD-TYPE	72	83	80

'SLC1A3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0306 (Fisher's exact test), Q value = 0.28

Table S816. Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SLC1A3 MUTATED	1	0	2	2	5	0	2
SLC1A3 WILD-TYPE	43	41	15	31	30	31	44

Figure S186. Get High-res Image Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SLC1A3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.312 (Fisher's exact test), Q value = 0.72

Table S817. Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SLC1A3 MUTATED	6	3	3
SLC1A3 WILD-TYPE	63	76	89

'SLC1A3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.289 (Fisher's exact test), Q value = 0.7

Table S818. Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SLC1A3 MUTATED	6	0	4	2
SLC1A3 WILD-TYPE	67	43	75	43

'SLC1A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 0.72

Table S819. Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
SLC1A3 MUTATED	2	2	2
SLC1A3 WILD-TYPE	27	17	62

'SLC1A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.423 (Fisher's exact test), Q value = 0.79

Table S820. Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
SLC1A3 MUTATED	3	1	2
SLC1A3 WILD-TYPE	30	47	29

'UFSP2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 0.88

Table S821. Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
UFSP2 MUTATED	2	2	0	0
UFSP2 WILD-TYPE	10	16	11	10

'UFSP2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 0.67

Table S822. Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
UFSP2 MUTATED	2	0	1	1	0
UFSP2 WILD-TYPE	10	10	6	6	15

'UFSP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 0.57

Table S823. Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
UFSP2 MUTATED	0	9	0	0	2
UFSP2 WILD-TYPE	56	143	11	5	16

'UFSP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.32 (Fisher's exact test), Q value = 0.73

Table S824. Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
UFSP2 MUTATED	3	0	3
UFSP2 WILD-TYPE	40	39	50

'UFSP2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.632 (Fisher's exact test), Q value = 0.95

Table S825. Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
UFSP2 MUTATED	5	4	2
UFSP2 WILD-TYPE	66	68	58

'UFSP2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.664 (Fisher's exact test), Q value = 0.97

Table S826. Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
UFSP2 MUTATED	2	6	2	1
UFSP2 WILD-TYPE	66	72	29	25

'UFSP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 0.61

Table S827. Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
UFSP2 MUTATED	5	5	1
UFSP2 WILD-TYPE	74	80	82

'UFSP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 8e-05 (Fisher's exact test), Q value = 0.0045

Table S828. Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
UFSP2 MUTATED	0	0	1	6	4	0	0
UFSP2 WILD-TYPE	44	41	16	27	31	31	46

Figure S187. Get High-res Image Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'UFSP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 0.77

Table S829. Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
UFSP2 MUTATED	3	5	2
UFSP2 WILD-TYPE	66	74	90

'UFSP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0789 (Fisher's exact test), Q value = 0.43

Table S830. Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
UFSP2 MUTATED	7	1	1	1
UFSP2 WILD-TYPE	66	42	78	44

'UFSP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0185 (Fisher's exact test), Q value = 0.21

Table S831. Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
UFSP2 MUTATED	0	3	1
UFSP2 WILD-TYPE	29	16	63

Figure S188. Get High-res Image Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'UFSP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0356 (Fisher's exact test), Q value = 0.3

Table S832. Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
UFSP2 MUTATED	1	0	3
UFSP2 WILD-TYPE	32	48	28

Figure S189. Get High-res Image Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'WBP4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.392 (Fisher's exact test), Q value = 0.77

Table S833. Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
WBP4 MUTATED	0	7	0	0	1
WBP4 WILD-TYPE	56	145	11	5	17

'WBP4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 0.5

Table S834. Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
WBP4 MUTATED	1	0	5
WBP4 WILD-TYPE	42	39	48

'WBP4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S835. Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
WBP4 MUTATED	3	3	2
WBP4 WILD-TYPE	68	69	58

'WBP4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.872 (Fisher's exact test), Q value = 1

Table S836. Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
WBP4 MUTATED	2	3	2	1
WBP4 WILD-TYPE	66	75	29	25

'WBP4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.364 (Fisher's exact test), Q value = 0.77

Table S837. Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
WBP4 MUTATED	4	3	1
WBP4 WILD-TYPE	75	82	82

'WBP4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 9e-04 (Fisher's exact test), Q value = 0.027

Table S838. Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
WBP4 MUTATED	0	0	0	4	4	0	0
WBP4 WILD-TYPE	44	41	17	29	31	31	46

Figure S190. Get High-res Image Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'WBP4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0781 (Fisher's exact test), Q value = 0.43

Table S839. Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
WBP4 MUTATED	0	5	2
WBP4 WILD-TYPE	69	74	90

'WBP4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.149 (Fisher's exact test), Q value = 0.55

Table S840. Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
WBP4 MUTATED	5	0	1	1
WBP4 WILD-TYPE	68	43	78	44

'WBP4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 0.89

Table S841. Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
WBP4 MUTATED	0	1	2
WBP4 WILD-TYPE	29	18	62

'WBP4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.113 (Fisher's exact test), Q value = 0.51

Table S842. Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
WBP4 MUTATED	1	0	2
WBP4 WILD-TYPE	32	48	29

'TRIM59 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 0.52

Table S843. Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
TRIM59 MUTATED	0	8	0	1	0
TRIM59 WILD-TYPE	56	144	11	4	18

'TRIM59 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.86 (Fisher's exact test), Q value = 1

Table S844. Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
TRIM59 MUTATED	1	2	2
TRIM59 WILD-TYPE	42	37	51

'TRIM59 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.542 (Fisher's exact test), Q value = 0.88

Table S845. Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
TRIM59 MUTATED	4	3	1
TRIM59 WILD-TYPE	67	69	59

'TRIM59 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.907 (Fisher's exact test), Q value = 1

Table S846. Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
TRIM59 MUTATED	3	4	1	0
TRIM59 WILD-TYPE	65	74	30	26

'TRIM59 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.704 (Fisher's exact test), Q value = 0.98

Table S847. Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
TRIM59 MUTATED	3	2	4
TRIM59 WILD-TYPE	76	83	79

'TRIM59 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0776 (Fisher's exact test), Q value = 0.43

Table S848. Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
TRIM59 MUTATED	0	0	0	3	3	2	1
TRIM59 WILD-TYPE	44	41	17	30	32	29	45

'TRIM59 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.668 (Fisher's exact test), Q value = 0.97

Table S849. Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
TRIM59 MUTATED	1	3	4
TRIM59 WILD-TYPE	68	76	88

'TRIM59 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.16 (Fisher's exact test), Q value = 0.57

Table S850. Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
TRIM59 MUTATED	5	0	3	0
TRIM59 WILD-TYPE	68	43	76	45

'TRIM59 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 0.59

Table S851. Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
TRIM59 MUTATED	0	2	2
TRIM59 WILD-TYPE	29	17	62

'TRIM59 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00487 (Fisher's exact test), Q value = 0.086

Table S852. Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
TRIM59 MUTATED	0	0	4
TRIM59 WILD-TYPE	33	48	27

Figure S191. Get High-res Image Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'RSBN1L MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 0.53

Table S853. Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
RSBN1L MUTATED	3	1	0	0
RSBN1L WILD-TYPE	9	17	11	10

'RSBN1L MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0924 (Fisher's exact test), Q value = 0.46

Table S854. Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
RSBN1L MUTATED	1	0	1	2	0
RSBN1L WILD-TYPE	11	10	6	5	15

'RSBN1L MUTATION STATUS' versus 'CN_CNMF'

P value = 0.179 (Fisher's exact test), Q value = 0.59

Table S855. Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
RSBN1L MUTATED	1	8	0	0	3
RSBN1L WILD-TYPE	55	144	11	5	15

'RSBN1L MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.555 (Fisher's exact test), Q value = 0.89

Table S856. Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
RSBN1L MUTATED	2	0	2
RSBN1L WILD-TYPE	41	39	51

'RSBN1L MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.37 (Fisher's exact test), Q value = 0.77

Table S857. Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
RSBN1L MUTATED	4	2	5
RSBN1L WILD-TYPE	67	70	55

'RSBN1L MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.216 (Fisher's exact test), Q value = 0.62

Table S858. Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
RSBN1L MUTATED	3	4	4	0
RSBN1L WILD-TYPE	65	74	27	26

'RSBN1L MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.297 (Fisher's exact test), Q value = 0.71

Table S859. Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
RSBN1L MUTATED	6	4	2
RSBN1L WILD-TYPE	73	81	81

'RSBN1L MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0044 (Fisher's exact test), Q value = 0.081

Table S860. Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
RSBN1L MUTATED	0	0	1	3	6	1	1
RSBN1L WILD-TYPE	44	41	16	30	29	30	45

Figure S192. Get High-res Image Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RSBN1L MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.369 (Fisher's exact test), Q value = 0.77

Table S861. Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
RSBN1L MUTATED	4	5	2
RSBN1L WILD-TYPE	65	74	90

'RSBN1L MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.735 (Fisher's exact test), Q value = 0.99

Table S862. Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
RSBN1L MUTATED	5	1	3	2
RSBN1L WILD-TYPE	68	42	76	43

'SERHL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 0.88

Table S863. Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SERHL2 MUTATED	0	6	0	0	0
SERHL2 WILD-TYPE	56	146	11	5	18

'SERHL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S864. Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SERHL2 MUTATED	1	1	2
SERHL2 WILD-TYPE	42	38	51

'SERHL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.379 (Fisher's exact test), Q value = 0.77

Table S865. Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SERHL2 MUTATED	1	4	1
SERHL2 WILD-TYPE	70	68	59

'SERHL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.937 (Fisher's exact test), Q value = 1

Table S866. Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SERHL2 MUTATED	2	3	1	0
SERHL2 WILD-TYPE	66	75	30	26

'SERHL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S867. Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SERHL2 MUTATED	2	2	2
SERHL2 WILD-TYPE	77	83	81

'SERHL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 0.76

Table S868. Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SERHL2 MUTATED	0	1	1	0	2	0	2
SERHL2 WILD-TYPE	44	40	16	33	33	31	44

'SERHL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.74 (Fisher's exact test), Q value = 0.99

Table S869. Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SERHL2 MUTATED	1	1	3
SERHL2 WILD-TYPE	68	78	89

'SERHL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.716 (Fisher's exact test), Q value = 0.98

Table S870. Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SERHL2 MUTATED	1	1	3	0
SERHL2 WILD-TYPE	72	42	76	45

'SERHL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.806 (Fisher's exact test), Q value = 1

Table S871. Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
SERHL2 MUTATED	1	1	2
SERHL2 WILD-TYPE	28	18	62

'SERHL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S872. Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
SERHL2 MUTATED	1	2	1
SERHL2 WILD-TYPE	32	46	30

'OR52I2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.686 (Fisher's exact test), Q value = 0.97

Table S873. Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
OR52I2 MUTATED	1	2	0	0
OR52I2 WILD-TYPE	11	16	11	10

'OR52I2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.534 (Fisher's exact test), Q value = 0.88

Table S874. Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
OR52I2 MUTATED	1	1	0	1	0
OR52I2 WILD-TYPE	11	9	7	6	15

'OR52I2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.704 (Fisher's exact test), Q value = 0.98

Table S875. Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
OR52I2 MUTATED	1	6	0	0	1
OR52I2 WILD-TYPE	55	146	11	5	17

'OR52I2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0371 (Fisher's exact test), Q value = 0.3

Table S876. Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
OR52I2 MUTATED	0	0	4
OR52I2 WILD-TYPE	43	39	49

Figure S193. Get High-res Image Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'OR52I2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0652 (Fisher's exact test), Q value = 0.39

Table S877. Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
OR52I2 MUTATED	2	0	4
OR52I2 WILD-TYPE	69	72	56

'OR52I2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S878. Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
OR52I2 MUTATED	1	3	1	1
OR52I2 WILD-TYPE	67	75	30	25

'OR52I2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.155 (Fisher's exact test), Q value = 0.57

Table S879. Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
OR52I2 MUTATED	5	1	2
OR52I2 WILD-TYPE	74	84	81

'OR52I2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0982 (Fisher's exact test), Q value = 0.47

Table S880. Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
OR52I2 MUTATED	1	0	0	2	4	0	1
OR52I2 WILD-TYPE	43	41	17	31	31	31	45

'OR52I2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.714 (Fisher's exact test), Q value = 0.98

Table S881. Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
OR52I2 MUTATED	3	2	2
OR52I2 WILD-TYPE	66	77	90

'OR52I2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.665 (Fisher's exact test), Q value = 0.97

Table S882. Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
OR52I2 MUTATED	2	0	3	2
OR52I2 WILD-TYPE	71	43	76	43

'OR52I2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S883. Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
OR52I2 MUTATED	1	0	2
OR52I2 WILD-TYPE	28	19	62

'OR52I2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S884. Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
OR52I2 MUTATED	1	1	1
OR52I2 WILD-TYPE	32	47	30

'SGK1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 0.77

Table S885. Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
SGK1 MUTATED	2	1	0	0
SGK1 WILD-TYPE	10	17	11	10

'SGK1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.283 (Fisher's exact test), Q value = 0.7

Table S886. Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
SGK1 MUTATED	1	0	1	1	0
SGK1 WILD-TYPE	11	10	6	6	15

'SGK1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.315 (Fisher's exact test), Q value = 0.73

Table S887. Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SGK1 MUTATED	1	9	1	0	2
SGK1 WILD-TYPE	55	143	10	5	16

'SGK1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.385 (Fisher's exact test), Q value = 0.77

Table S888. Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SGK1 MUTATED	1	0	3
SGK1 WILD-TYPE	42	39	50

'SGK1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.513 (Fisher's exact test), Q value = 0.87

Table S889. Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SGK1 MUTATED	5	6	2
SGK1 WILD-TYPE	66	66	58

'SGK1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S890. Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SGK1 MUTATED	5	5	2	1
SGK1 WILD-TYPE	63	73	29	25

'SGK1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.218 (Fisher's exact test), Q value = 0.62

Table S891. Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SGK1 MUTATED	4	7	2
SGK1 WILD-TYPE	75	78	81

'SGK1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.347 (Fisher's exact test), Q value = 0.76

Table S892. Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SGK1 MUTATED	0	3	2	2	3	1	2
SGK1 WILD-TYPE	44	38	15	31	32	30	44

'SGK1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 0.79

Table S893. Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SGK1 MUTATED	2	6	4
SGK1 WILD-TYPE	67	73	88

'SGK1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0702 (Fisher's exact test), Q value = 0.41

Table S894. Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SGK1 MUTATED	7	3	1	1
SGK1 WILD-TYPE	66	40	78	44

'LNX2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 0.77

Table S895. Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
LNX2 MUTATED	2	1	0	0
LNX2 WILD-TYPE	10	17	11	10

'LNX2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 0.7

Table S896. Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
LNX2 MUTATED	1	0	1	1	0
LNX2 WILD-TYPE	11	10	6	6	15

'LNX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.121 (Fisher's exact test), Q value = 0.52

Table S897. Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
LNX2 MUTATED	0	12	0	0	2
LNX2 WILD-TYPE	56	140	11	5	16

'LNX2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00271 (Fisher's exact test), Q value = 0.058

Table S898. Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
LNX2 MUTATED	0	0	7
LNX2 WILD-TYPE	43	39	46

Figure S194. Get High-res Image Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'LNX2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.933 (Fisher's exact test), Q value = 1

Table S899. Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
LNX2 MUTATED	4	5	3
LNX2 WILD-TYPE	67	67	57

'LNX2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.381 (Fisher's exact test), Q value = 0.77

Table S900. Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
LNX2 MUTATED	3	4	4	1
LNX2 WILD-TYPE	65	74	27	25

'LNX2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0237 (Fisher's exact test), Q value = 0.23

Table S901. Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
LNX2 MUTATED	4	9	1
LNX2 WILD-TYPE	75	76	82

Figure S195. Get High-res Image Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'LNX2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00296 (Fisher's exact test), Q value = 0.061

Table S902. Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
LNX2 MUTATED	0	1	0	5	6	1	1
LNX2 WILD-TYPE	44	40	17	28	29	30	45

Figure S196. Get High-res Image Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'LNX2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 0.79

Table S903. Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
LNX2 MUTATED	3	7	4
LNX2 WILD-TYPE	66	72	88

'LNX2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 0.59

Table S904. Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
LNX2 MUTATED	8	2	2	2
LNX2 WILD-TYPE	65	41	77	43

'LNX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S905. Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
LNX2 MUTATED	1	0	2
LNX2 WILD-TYPE	28	19	62

'LNX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.467 (Fisher's exact test), Q value = 0.82

Table S906. Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
LNX2 MUTATED	2	1	0
LNX2 WILD-TYPE	31	47	31

'ALPK2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0315 (Fisher's exact test), Q value = 0.28

Table S907. Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ALPK2 MUTATED	4	1	0	0
ALPK2 WILD-TYPE	8	17	11	10

Figure S197. Get High-res Image Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'ALPK2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0147 (Fisher's exact test), Q value = 0.19

Table S908. Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ALPK2 MUTATED	1	0	1	3	0
ALPK2 WILD-TYPE	11	10	6	4	15

Figure S198. Get High-res Image Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'ALPK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0322 (Fisher's exact test), Q value = 0.29

Table S909. Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ALPK2 MUTATED	0	18	0	0	1
ALPK2 WILD-TYPE	56	134	11	5	17

Figure S199. Get High-res Image Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ALPK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 0.79

Table S910. Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ALPK2 MUTATED	3	1	5
ALPK2 WILD-TYPE	40	38	48

'ALPK2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.217 (Fisher's exact test), Q value = 0.62

Table S911. Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ALPK2 MUTATED	7	8	2
ALPK2 WILD-TYPE	64	64	58

'ALPK2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.355 (Fisher's exact test), Q value = 0.77

Table S912. Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ALPK2 MUTATED	6	5	5	1
ALPK2 WILD-TYPE	62	73	26	25

'ALPK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.246 (Fisher's exact test), Q value = 0.66

Table S913. Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ALPK2 MUTATED	5	10	4
ALPK2 WILD-TYPE	74	75	79

'ALPK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00369 (Fisher's exact test), Q value = 0.073

Table S914. Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ALPK2 MUTATED	0	2	3	7	4	2	1
ALPK2 WILD-TYPE	44	39	14	26	31	29	45

Figure S200. Get High-res Image Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ALPK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 0.92

Table S915. Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ALPK2 MUTATED	4	8	7
ALPK2 WILD-TYPE	65	71	85

'ALPK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.58 (Fisher's exact test), Q value = 0.9

Table S916. Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ALPK2 MUTATED	8	4	5	2
ALPK2 WILD-TYPE	65	39	74	43

'ALPK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 0.78

Table S917. Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ALPK2 MUTATED	3	2	3
ALPK2 WILD-TYPE	26	17	61

'ALPK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.532 (Fisher's exact test), Q value = 0.88

Table S918. Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ALPK2 MUTATED	3	2	3
ALPK2 WILD-TYPE	30	46	28

'REV3L MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 0.77

Table S919. Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
REV3L MUTATED	2	1	0	0
REV3L WILD-TYPE	10	17	11	10

'REV3L MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.28 (Fisher's exact test), Q value = 0.7

Table S920. Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
REV3L MUTATED	1	0	1	1	0
REV3L WILD-TYPE	11	10	6	6	15

'REV3L MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0259 (Fisher's exact test), Q value = 0.25

Table S921. Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
REV3L MUTATED	0	19	0	0	1
REV3L WILD-TYPE	56	133	11	5	17

Figure S201. Get High-res Image Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'REV3L MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.327 (Fisher's exact test), Q value = 0.74

Table S922. Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
REV3L MUTATED	2	4	7
REV3L WILD-TYPE	41	35	46

'REV3L MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S923. Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
REV3L MUTATED	7	6	4
REV3L WILD-TYPE	64	66	56

'REV3L MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.651 (Fisher's exact test), Q value = 0.96

Table S924. Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
REV3L MUTATED	5	7	4	1
REV3L WILD-TYPE	63	71	27	25

'REV3L MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.561 (Fisher's exact test), Q value = 0.89

Table S925. Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
REV3L MUTATED	6	9	5
REV3L WILD-TYPE	73	76	78

'REV3L MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 9e-04 (Fisher's exact test), Q value = 0.027

Table S926. Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
REV3L MUTATED	0	1	1	8	6	1	3
REV3L WILD-TYPE	44	40	16	25	29	30	43

Figure S202. Get High-res Image Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'REV3L MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 0.92

Table S927. Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
REV3L MUTATED	4	8	7
REV3L WILD-TYPE	65	71	85

'REV3L MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0663 (Fisher's exact test), Q value = 0.4

Table S928. Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
REV3L MUTATED	11	2	5	1
REV3L WILD-TYPE	62	41	74	44

'REV3L MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 0.72

Table S929. Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
REV3L MUTATED	1	3	6
REV3L WILD-TYPE	28	16	58

'REV3L MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.282 (Fisher's exact test), Q value = 0.7

Table S930. Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
REV3L MUTATED	4	2	4
REV3L WILD-TYPE	29	46	27

'CAB39L MUTATION STATUS' versus 'CN_CNMF'

P value = 0.394 (Fisher's exact test), Q value = 0.77

Table S931. Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CAB39L MUTATED	0	7	0	0	1
CAB39L WILD-TYPE	56	145	11	5	17

'CAB39L MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S932. Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CAB39L MUTATED	2	3	1
CAB39L WILD-TYPE	69	69	59

'CAB39L MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.147 (Fisher's exact test), Q value = 0.55

Table S933. Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CAB39L MUTATED	2	1	3	0
CAB39L WILD-TYPE	66	77	28	26

'CAB39L MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.738 (Fisher's exact test), Q value = 0.99

Table S934. Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CAB39L MUTATED	2	4	2
CAB39L WILD-TYPE	77	81	81

'CAB39L MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0198 (Fisher's exact test), Q value = 0.21

Table S935. Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CAB39L MUTATED	0	3	0	0	4	1	0
CAB39L WILD-TYPE	44	38	17	33	31	30	46

Figure S203. Get High-res Image Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CAB39L MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.602 (Fisher's exact test), Q value = 0.92

Table S936. Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CAB39L MUTATED	2	4	2
CAB39L WILD-TYPE	67	75	90

'CAB39L MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.338 (Fisher's exact test), Q value = 0.75

Table S937. Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CAB39L MUTATED	3	3	1	1
CAB39L WILD-TYPE	70	40	78	44

'ERBB3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 0.58

Table S938. Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ERBB3 MUTATED	1	13	0	0	3
ERBB3 WILD-TYPE	55	139	11	5	15

'ERBB3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 0.85

Table S939. Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ERBB3 MUTATED	2	3	6
ERBB3 WILD-TYPE	41	36	47

'ERBB3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0656 (Fisher's exact test), Q value = 0.39

Table S940. Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ERBB3 MUTATED	9	2	3
ERBB3 WILD-TYPE	62	70	57

'ERBB3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0379 (Fisher's exact test), Q value = 0.31

Table S941. Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ERBB3 MUTATED	5	2	2	5
ERBB3 WILD-TYPE	63	76	29	21

Figure S204. Get High-res Image Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'ERBB3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.211 (Fisher's exact test), Q value = 0.61

Table S942. Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ERBB3 MUTATED	5	9	3
ERBB3 WILD-TYPE	74	76	80

'ERBB3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.27 (Fisher's exact test), Q value = 0.7

Table S943. Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ERBB3 MUTATED	2	2	1	5	4	0	3
ERBB3 WILD-TYPE	42	39	16	28	31	31	43

'ERBB3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.952 (Fisher's exact test), Q value = 1

Table S944. Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ERBB3 MUTATED	5	5	7
ERBB3 WILD-TYPE	64	74	85

'ERBB3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.821 (Fisher's exact test), Q value = 1

Table S945. Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ERBB3 MUTATED	7	2	5	3
ERBB3 WILD-TYPE	66	41	74	42

'ERBB3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.664 (Fisher's exact test), Q value = 0.97

Table S946. Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ERBB3 MUTATED	2	0	5
ERBB3 WILD-TYPE	27	19	59

'ERBB3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.555 (Fisher's exact test), Q value = 0.89

Table S947. Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ERBB3 MUTATED	2	2	3
ERBB3 WILD-TYPE	31	46	28

'INPP4B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.458 (Fisher's exact test), Q value = 0.82

Table S948. Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
INPP4B MUTATED	1	3	0	0
INPP4B WILD-TYPE	11	15	11	10

'INPP4B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0792 (Fisher's exact test), Q value = 0.43

Table S949. Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
INPP4B MUTATED	3	0	1	0	0
INPP4B WILD-TYPE	9	10	6	7	15

'INPP4B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.275 (Fisher's exact test), Q value = 0.7

Table S950. Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
INPP4B MUTATED	0	10	0	0	1
INPP4B WILD-TYPE	56	142	11	5	17

'INPP4B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.696 (Fisher's exact test), Q value = 0.98

Table S951. Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
INPP4B MUTATED	4	2	3
INPP4B WILD-TYPE	67	70	57

'INPP4B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.391 (Fisher's exact test), Q value = 0.77

Table S952. Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
INPP4B MUTATED	3	3	3	0
INPP4B WILD-TYPE	65	75	28	26

'INPP4B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S953. Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
INPP4B MUTATED	4	4	4
INPP4B WILD-TYPE	75	81	79

'INPP4B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0022 (Fisher's exact test), Q value = 0.051

Table S954. Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
INPP4B MUTATED	0	0	0	3	6	0	3
INPP4B WILD-TYPE	44	41	17	30	29	31	43

Figure S205. Get High-res Image Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'INPP4B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.635 (Fisher's exact test), Q value = 0.95

Table S955. Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
INPP4B MUTATED	2	5	4
INPP4B WILD-TYPE	67	74	88

'INPP4B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S956. Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
INPP4B MUTATED	3	1	5	2
INPP4B WILD-TYPE	70	42	74	43

'C1ORF100 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 0.77

Table S957. Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
C1ORF100 MUTATED	2	1	0	0
C1ORF100 WILD-TYPE	10	17	11	10

'C1ORF100 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.28 (Fisher's exact test), Q value = 0.7

Table S958. Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
C1ORF100 MUTATED	1	0	1	1	0
C1ORF100 WILD-TYPE	11	10	6	6	15

'C1ORF100 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0621 (Fisher's exact test), Q value = 0.39

Table S959. Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
C1ORF100 MUTATED	0	6	0	0	3
C1ORF100 WILD-TYPE	56	146	11	5	15

'C1ORF100 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S960. Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
C1ORF100 MUTATED	1	1	1
C1ORF100 WILD-TYPE	42	38	52

'C1ORF100 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.398 (Fisher's exact test), Q value = 0.77

Table S961. Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
C1ORF100 MUTATED	1	4	2
C1ORF100 WILD-TYPE	70	68	58

'C1ORF100 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.322 (Fisher's exact test), Q value = 0.73

Table S962. Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
C1ORF100 MUTATED	1	5	1	0
C1ORF100 WILD-TYPE	67	73	30	26

'C1ORF100 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 0.67

Table S963. Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
C1ORF100 MUTATED	3	5	1
C1ORF100 WILD-TYPE	76	80	82

'C1ORF100 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0146 (Fisher's exact test), Q value = 0.19

Table S964. Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
C1ORF100 MUTATED	0	0	1	4	3	0	1
C1ORF100 WILD-TYPE	44	41	16	29	32	31	45

Figure S206. Get High-res Image Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'C1ORF100 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0928 (Fisher's exact test), Q value = 0.46

Table S965. Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
C1ORF100 MUTATED	2	6	1
C1ORF100 WILD-TYPE	67	73	91

'C1ORF100 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.569 (Fisher's exact test), Q value = 0.89

Table S966. Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
C1ORF100 MUTATED	5	1	2	1
C1ORF100 WILD-TYPE	68	42	77	44

'IL20 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.135 (Fisher's exact test), Q value = 0.53

Table S967. Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
IL20 MUTATED	3	1	0	0
IL20 WILD-TYPE	9	17	11	10

'IL20 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0922 (Fisher's exact test), Q value = 0.46

Table S968. Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
IL20 MUTATED	1	0	1	2	0
IL20 WILD-TYPE	11	10	6	5	15

'IL20 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.433 (Fisher's exact test), Q value = 0.8

Table S969. Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
IL20 MUTATED	0	6	0	0	1
IL20 WILD-TYPE	56	146	11	5	17

'IL20 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.517 (Fisher's exact test), Q value = 0.87

Table S970. Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
IL20 MUTATED	1	2	3
IL20 WILD-TYPE	70	70	57

'IL20 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.541 (Fisher's exact test), Q value = 0.88

Table S971. Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
IL20 MUTATED	1	4	1	0
IL20 WILD-TYPE	67	74	30	26

'IL20 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.631 (Fisher's exact test), Q value = 0.95

Table S972. Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
IL20 MUTATED	3	3	1
IL20 WILD-TYPE	76	82	82

'IL20 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0176 (Fisher's exact test), Q value = 0.2

Table S973. Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
IL20 MUTATED	0	1	0	4	2	0	0
IL20 WILD-TYPE	44	40	17	29	33	31	46

Figure S207. Get High-res Image Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'IL20 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.284 (Fisher's exact test), Q value = 0.7

Table S974. Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
IL20 MUTATED	1	4	1
IL20 WILD-TYPE	68	75	91

'IL20 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.365 (Fisher's exact test), Q value = 0.77

Table S975. Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
IL20 MUTATED	3	2	1	0
IL20 WILD-TYPE	70	41	78	45

'SLC44A3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.427 (Fisher's exact test), Q value = 0.79

Table S976. Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SLC44A3 MUTATED	0	5	0	0	1
SLC44A3 WILD-TYPE	56	147	11	5	17

'SLC44A3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 0.97

Table S977. Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SLC44A3 MUTATED	1	2	1
SLC44A3 WILD-TYPE	42	37	52

'SLC44A3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S978. Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SLC44A3 MUTATED	2	2	2
SLC44A3 WILD-TYPE	69	70	58

'SLC44A3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.939 (Fisher's exact test), Q value = 1

Table S979. Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SLC44A3 MUTATED	2	3	1	0
SLC44A3 WILD-TYPE	66	75	30	26

'SLC44A3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S980. Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SLC44A3 MUTATED	2	2	2
SLC44A3 WILD-TYPE	77	83	81

'SLC44A3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.252 (Fisher's exact test), Q value = 0.67

Table S981. Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SLC44A3 MUTATED	0	0	0	2	2	0	2
SLC44A3 WILD-TYPE	44	41	17	31	33	31	44

'SLC44A3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.679 (Fisher's exact test), Q value = 0.97

Table S982. Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SLC44A3 MUTATED	1	3	2
SLC44A3 WILD-TYPE	68	76	90

'SLC44A3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.275 (Fisher's exact test), Q value = 0.7

Table S983. Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SLC44A3 MUTATED	4	0	2	0
SLC44A3 WILD-TYPE	69	43	77	45

'TAP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.197 (Fisher's exact test), Q value = 0.59

Table S984. Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
TAP1 MUTATED	0	6	0	0	2
TAP1 WILD-TYPE	56	146	11	5	16

'TAP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S985. Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
TAP1 MUTATED	1	0	2
TAP1 WILD-TYPE	42	39	51

'TAP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S986. Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
TAP1 MUTATED	2	3	2
TAP1 WILD-TYPE	69	69	58

'TAP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.676 (Fisher's exact test), Q value = 0.97

Table S987. Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
TAP1 MUTATED	1	4	1	1
TAP1 WILD-TYPE	67	74	30	25

'TAP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.123 (Fisher's exact test), Q value = 0.52

Table S988. Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
TAP1 MUTATED	4	4	0
TAP1 WILD-TYPE	75	81	83

'TAP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00258 (Fisher's exact test), Q value = 0.056

Table S989. Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
TAP1 MUTATED	0	0	1	3	4	0	0
TAP1 WILD-TYPE	44	41	16	30	31	31	46

Figure S208. Get High-res Image Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TAP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.338 (Fisher's exact test), Q value = 0.75

Table S990. Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
TAP1 MUTATED	2	4	1
TAP1 WILD-TYPE	67	75	91

'TAP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0254 (Fisher's exact test), Q value = 0.25

Table S991. Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
TAP1 MUTATED	6	0	1	0
TAP1 WILD-TYPE	67	43	78	45

Figure S209. Get High-res Image Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'RHBDD3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S992. Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
RHBDD3 MUTATED	0	4	0	0	0
RHBDD3 WILD-TYPE	56	148	11	5	18

'RHBDD3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.112 (Fisher's exact test), Q value = 0.51

Table S993. Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
RHBDD3 MUTATED	0	0	3
RHBDD3 WILD-TYPE	43	39	50

'RHBDD3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 0.77

Table S994. Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
RHBDD3 MUTATED	2	0	2
RHBDD3 WILD-TYPE	69	72	58

'RHBDD3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.106 (Fisher's exact test), Q value = 0.5

Table S995. Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
RHBDD3 MUTATED	0	2	0	2
RHBDD3 WILD-TYPE	68	76	31	24

'RHBDD3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.223 (Fisher's exact test), Q value = 0.63

Table S996. Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
RHBDD3 MUTATED	1	3	0
RHBDD3 WILD-TYPE	78	82	83

'RHBDD3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.023 (Fisher's exact test), Q value = 0.23

Table S997. Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
RHBDD3 MUTATED	0	0	0	3	1	0	0
RHBDD3 WILD-TYPE	44	41	17	30	34	31	46

Figure S210. Get High-res Image Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RHBDD3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.685 (Fisher's exact test), Q value = 0.97

Table S998. Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
RHBDD3 MUTATED	2	1	1
RHBDD3 WILD-TYPE	67	78	91

'RHBDD3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0472 (Fisher's exact test), Q value = 0.33

Table S999. Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
RHBDD3 MUTATED	4	0	0	0
RHBDD3 WILD-TYPE	69	43	79	45

Figure S211. Get High-res Image Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'BRDT MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1000. Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
BRDT MUTATED	1	1	1	0
BRDT WILD-TYPE	11	17	10	10

'BRDT MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.913 (Fisher's exact test), Q value = 1

Table S1001. Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
BRDT MUTATED	1	0	1	0	1
BRDT WILD-TYPE	11	10	6	7	14

'BRDT MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0538 (Fisher's exact test), Q value = 0.36

Table S1002. Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
BRDT MUTATED	0	11	0	0	3
BRDT WILD-TYPE	56	141	11	5	15

'BRDT MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.634 (Fisher's exact test), Q value = 0.95

Table S1003. Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
BRDT MUTATED	2	1	4
BRDT WILD-TYPE	41	38	49

'BRDT MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S1004. Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
BRDT MUTATED	4	6	3
BRDT WILD-TYPE	67	66	57

'BRDT MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.236 (Fisher's exact test), Q value = 0.65

Table S1005. Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
BRDT MUTATED	2	6	4	1
BRDT WILD-TYPE	66	72	27	25

'BRDT MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.546 (Fisher's exact test), Q value = 0.89

Table S1006. Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
BRDT MUTATED	6	5	3
BRDT WILD-TYPE	73	80	80

'BRDT MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00754 (Fisher's exact test), Q value = 0.11

Table S1007. Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
BRDT MUTATED	0	1	1	4	6	0	2
BRDT WILD-TYPE	44	40	16	29	29	31	44

Figure S212. Get High-res Image Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'BRDT MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.938 (Fisher's exact test), Q value = 1

Table S1008. Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
BRDT MUTATED	3	5	5
BRDT WILD-TYPE	66	74	87

'BRDT MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.363 (Fisher's exact test), Q value = 0.77

Table S1009. Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
BRDT MUTATED	7	2	3	1
BRDT WILD-TYPE	66	41	76	44

'BRDT MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 0.59

Table S1010. Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
BRDT MUTATED	0	2	2
BRDT WILD-TYPE	29	17	62

'BRDT MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.688 (Fisher's exact test), Q value = 0.97

Table S1011. Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
BRDT MUTATED	1	1	2
BRDT WILD-TYPE	32	47	29

'RB1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 0.95

Table S1012. Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
RB1 MUTATED	1	3	2	0
RB1 WILD-TYPE	11	15	9	10

'RB1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00568 (Fisher's exact test), Q value = 0.093

Table S1013. Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
RB1 MUTATED	5	0	0	1	0
RB1 WILD-TYPE	7	10	7	6	15

Figure S213. Get High-res Image Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 0.79

Table S1014. Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
RB1 MUTATED	2	16	0	0	2
RB1 WILD-TYPE	54	136	11	5	16

'RB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.256 (Fisher's exact test), Q value = 0.68

Table S1015. Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
RB1 MUTATED	2	1	6
RB1 WILD-TYPE	41	38	47

'RB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.501 (Fisher's exact test), Q value = 0.85

Table S1016. Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
RB1 MUTATED	8	4	6
RB1 WILD-TYPE	63	68	54

'RB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 0.87

Table S1017. Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
RB1 MUTATED	5	6	5	2
RB1 WILD-TYPE	63	72	26	24

'RB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 0.83

Table S1018. Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
RB1 MUTATED	9	6	5
RB1 WILD-TYPE	70	79	78

'RB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 7e-05 (Fisher's exact test), Q value = 0.004

Table S1019. Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
RB1 MUTATED	2	0	0	5	10	2	1
RB1 WILD-TYPE	42	41	17	28	25	29	45

Figure S214. Get High-res Image Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.163 (Fisher's exact test), Q value = 0.58

Table S1020. Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
RB1 MUTATED	3	10	6
RB1 WILD-TYPE	66	69	86

'RB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0226 (Fisher's exact test), Q value = 0.23

Table S1021. Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
RB1 MUTATED	11	0	5	3
RB1 WILD-TYPE	62	43	74	42

Figure S215. Get High-res Image Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.805 (Fisher's exact test), Q value = 1

Table S1022. Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
RB1 MUTATED	1	1	2
RB1 WILD-TYPE	28	18	62

'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.172 (Fisher's exact test), Q value = 0.58

Table S1023. Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
RB1 MUTATED	2	0	2
RB1 WILD-TYPE	31	48	29

'MFAP5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.374 (Fisher's exact test), Q value = 0.77

Table S1024. Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MFAP5 MUTATED	0	8	0	0	1
MFAP5 WILD-TYPE	56	144	11	5	17

'MFAP5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.518 (Fisher's exact test), Q value = 0.87

Table S1025. Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MFAP5 MUTATED	3	1	1
MFAP5 WILD-TYPE	40	38	52

'MFAP5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.391 (Fisher's exact test), Q value = 0.77

Table S1026. Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MFAP5 MUTATED	3	5	1
MFAP5 WILD-TYPE	68	67	59

'MFAP5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0163 (Fisher's exact test), Q value = 0.19

Table S1027. Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MFAP5 MUTATED	1	3	5	0
MFAP5 WILD-TYPE	67	75	26	26

Figure S216. Get High-res Image Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'MFAP5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.642 (Fisher's exact test), Q value = 0.95

Table S1028. Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MFAP5 MUTATED	4	3	2
MFAP5 WILD-TYPE	75	82	81

'MFAP5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00323 (Fisher's exact test), Q value = 0.065

Table S1029. Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MFAP5 MUTATED	0	0	3	2	3	1	0
MFAP5 WILD-TYPE	44	41	14	31	32	30	46

Figure S217. Get High-res Image Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MFAP5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.196 (Fisher's exact test), Q value = 0.59

Table S1030. Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MFAP5 MUTATED	4	4	1
MFAP5 WILD-TYPE	65	75	91

'MFAP5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.32 (Fisher's exact test), Q value = 0.73

Table S1031. Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MFAP5 MUTATED	4	1	1	3
MFAP5 WILD-TYPE	69	42	78	42

'MFAP5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0417 (Fisher's exact test), Q value = 0.32

Table S1032. Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MFAP5 MUTATED	1	2	0
MFAP5 WILD-TYPE	28	17	64

Figure S218. Get High-res Image Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'MFAP5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.183 (Fisher's exact test), Q value = 0.59

Table S1033. Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MFAP5 MUTATED	2	0	1
MFAP5 WILD-TYPE	31	48	30

'NAA15 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.537 (Fisher's exact test), Q value = 0.88

Table S1034. Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
NAA15 MUTATED	2	2	0	0
NAA15 WILD-TYPE	10	16	11	10

'NAA15 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.248 (Fisher's exact test), Q value = 0.67

Table S1035. Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
NAA15 MUTATED	2	0	1	1	0
NAA15 WILD-TYPE	10	10	6	6	15

'NAA15 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.655 (Fisher's exact test), Q value = 0.96

Table S1036. Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
NAA15 MUTATED	2	10	0	0	2
NAA15 WILD-TYPE	54	142	11	5	16

'NAA15 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0984 (Fisher's exact test), Q value = 0.47

Table S1037. Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
NAA15 MUTATED	5	1	1
NAA15 WILD-TYPE	38	38	52

'NAA15 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S1038. Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
NAA15 MUTATED	5	5	3
NAA15 WILD-TYPE	66	67	57

'NAA15 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.482 (Fisher's exact test), Q value = 0.84

Table S1039. Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
NAA15 MUTATED	2	7	2	2
NAA15 WILD-TYPE	66	71	29	24

'NAA15 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 0.51

Table S1040. Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
NAA15 MUTATED	8	4	2
NAA15 WILD-TYPE	71	81	81

'NAA15 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00107 (Fisher's exact test), Q value = 0.03

Table S1041. Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
NAA15 MUTATED	0	0	3	4	5	0	2
NAA15 WILD-TYPE	44	41	14	29	30	31	44

Figure S219. Get High-res Image Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NAA15 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 0.59

Table S1042. Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
NAA15 MUTATED	5	6	2
NAA15 WILD-TYPE	64	73	90

'NAA15 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.375 (Fisher's exact test), Q value = 0.77

Table S1043. Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
NAA15 MUTATED	7	1	3	2
NAA15 WILD-TYPE	66	42	76	43

'NAA15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.192 (Fisher's exact test), Q value = 0.59

Table S1044. Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
NAA15 MUTATED	0	2	4
NAA15 WILD-TYPE	29	17	60

'NAA15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.373 (Fisher's exact test), Q value = 0.77

Table S1045. Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
NAA15 MUTATED	2	1	3
NAA15 WILD-TYPE	31	47	28

'ZRANB3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.431 (Fisher's exact test), Q value = 0.79

Table S1046. Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZRANB3 MUTATED	0	6	0	0	1
ZRANB3 WILD-TYPE	56	146	11	5	17

'ZRANB3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1047. Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZRANB3 MUTATED	2	2	2
ZRANB3 WILD-TYPE	69	70	58

'ZRANB3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.00831 (Fisher's exact test), Q value = 0.12

Table S1048. Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZRANB3 MUTATED	0	2	4	0
ZRANB3 WILD-TYPE	68	76	27	26

Figure S220. Get High-res Image Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'ZRANB3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.148 (Fisher's exact test), Q value = 0.55

Table S1049. Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZRANB3 MUTATED	3	4	0
ZRANB3 WILD-TYPE	76	81	83

'ZRANB3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00456 (Fisher's exact test), Q value = 0.083

Table S1050. Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZRANB3 MUTATED	0	0	1	2	4	0	0
ZRANB3 WILD-TYPE	44	41	16	31	31	31	46

Figure S221. Get High-res Image Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZRANB3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 0.51

Table S1051. Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZRANB3 MUTATED	3	3	0
ZRANB3 WILD-TYPE	66	76	92

'ZRANB3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.329 (Fisher's exact test), Q value = 0.74

Table S1052. Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZRANB3 MUTATED	4	0	1	1
ZRANB3 WILD-TYPE	69	43	78	44

'SLC34A3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 0.79

Table S1053. Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SLC34A3 MUTATED	0	5	0	0	1
SLC34A3 WILD-TYPE	56	147	11	5	17

'SLC34A3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 0.81

Table S1054. Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SLC34A3 MUTATED	2	0	3
SLC34A3 WILD-TYPE	41	39	50

'SLC34A3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 0.53

Table S1055. Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SLC34A3 MUTATED	1	4	0
SLC34A3 WILD-TYPE	70	68	60

'SLC34A3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.402 (Fisher's exact test), Q value = 0.77

Table S1056. Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SLC34A3 MUTATED	1	2	2	0
SLC34A3 WILD-TYPE	67	76	29	26

'SLC34A3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 0.81

Table S1057. Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SLC34A3 MUTATED	3	1	2
SLC34A3 WILD-TYPE	76	84	81

'SLC34A3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0417 (Fisher's exact test), Q value = 0.32

Table S1058. Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SLC34A3 MUTATED	0	0	1	3	1	1	0
SLC34A3 WILD-TYPE	44	41	16	30	34	30	46

Figure S222. Get High-res Image Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SLC34A3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.387 (Fisher's exact test), Q value = 0.77

Table S1059. Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SLC34A3 MUTATED	3	2	1
SLC34A3 WILD-TYPE	66	77	91

'SLC34A3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.275 (Fisher's exact test), Q value = 0.7

Table S1060. Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SLC34A3 MUTATED	4	0	2	0
SLC34A3 WILD-TYPE	69	43	77	45

'SLC34A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.358 (Fisher's exact test), Q value = 0.77

Table S1061. Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
SLC34A3 MUTATED	1	2	2
SLC34A3 WILD-TYPE	28	17	62

'SLC34A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0759 (Fisher's exact test), Q value = 0.43

Table S1062. Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
SLC34A3 MUTATED	2	0	3
SLC34A3 WILD-TYPE	31	48	28

'MLH3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S1063. Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
MLH3 MUTATED	1	2	1	0
MLH3 WILD-TYPE	11	16	10	10

'MLH3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0483 (Fisher's exact test), Q value = 0.33

Table S1064. Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
MLH3 MUTATED	2	0	2	0	0
MLH3 WILD-TYPE	10	10	5	7	15

Figure S223. Get High-res Image Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'MLH3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0617 (Fisher's exact test), Q value = 0.39

Table S1065. Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MLH3 MUTATED	0	16	0	0	1
MLH3 WILD-TYPE	56	136	11	5	17

'MLH3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1066. Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MLH3 MUTATED	3	2	4
MLH3 WILD-TYPE	40	37	49

'MLH3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.753 (Fisher's exact test), Q value = 1

Table S1067. Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MLH3 MUTATED	6	6	3
MLH3 WILD-TYPE	65	66	57

'MLH3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.56 (Fisher's exact test), Q value = 0.89

Table S1068. Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MLH3 MUTATED	4	6	4	1
MLH3 WILD-TYPE	64	72	27	25

'MLH3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.905 (Fisher's exact test), Q value = 1

Table S1069. Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MLH3 MUTATED	6	5	6
MLH3 WILD-TYPE	73	80	77

'MLH3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0522 (Fisher's exact test), Q value = 0.35

Table S1070. Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MLH3 MUTATED	0	1	2	4	5	1	4
MLH3 WILD-TYPE	44	40	15	29	30	30	42

'MLH3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.686 (Fisher's exact test), Q value = 0.97

Table S1071. Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MLH3 MUTATED	3	6	7
MLH3 WILD-TYPE	66	73	85

'MLH3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S1072. Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MLH3 MUTATED	7	2	5	2
MLH3 WILD-TYPE	66	41	74	43

'MLH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S1073. Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MLH3 MUTATED	1	2	4
MLH3 WILD-TYPE	28	17	60

'MLH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1074. Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MLH3 MUTATED	2	3	2
MLH3 WILD-TYPE	31	45	29

'CCDC147 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.683 (Fisher's exact test), Q value = 0.97

Table S1075. Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
CCDC147 MUTATED	2	1	1	0
CCDC147 WILD-TYPE	10	17	10	10

'CCDC147 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0907 (Fisher's exact test), Q value = 0.46

Table S1076. Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
CCDC147 MUTATED	1	0	2	1	0
CCDC147 WILD-TYPE	11	10	5	6	15

'CCDC147 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 0.5

Table S1077. Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CCDC147 MUTATED	0	14	0	0	1
CCDC147 WILD-TYPE	56	138	11	5	17

'CCDC147 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.66 (Fisher's exact test), Q value = 0.97

Table S1078. Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CCDC147 MUTATED	3	1	4
CCDC147 WILD-TYPE	40	38	49

'CCDC147 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.344 (Fisher's exact test), Q value = 0.76

Table S1079. Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CCDC147 MUTATED	4	7	2
CCDC147 WILD-TYPE	67	65	58

'CCDC147 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0131 (Fisher's exact test), Q value = 0.18

Table S1080. Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CCDC147 MUTATED	1	5	6	1
CCDC147 WILD-TYPE	67	73	25	25

Figure S224. Get High-res Image Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'CCDC147 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.537 (Fisher's exact test), Q value = 0.88

Table S1081. Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CCDC147 MUTATED	6	6	3
CCDC147 WILD-TYPE	73	79	80

'CCDC147 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00019 (Fisher's exact test), Q value = 0.0086

Table S1082. Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CCDC147 MUTATED	0	0	2	6	5	2	0
CCDC147 WILD-TYPE	44	41	15	27	30	29	46

Figure S225. Get High-res Image Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CCDC147 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.655 (Fisher's exact test), Q value = 0.96

Table S1083. Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CCDC147 MUTATED	4	6	4
CCDC147 WILD-TYPE	65	73	88

'CCDC147 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.233 (Fisher's exact test), Q value = 0.64

Table S1084. Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CCDC147 MUTATED	8	1	3	2
CCDC147 WILD-TYPE	65	42	76	43

'CCDC147 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.362 (Fisher's exact test), Q value = 0.77

Table S1085. Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CCDC147 MUTATED	1	2	2
CCDC147 WILD-TYPE	28	17	62

'CCDC147 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0765 (Fisher's exact test), Q value = 0.43

Table S1086. Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CCDC147 MUTATED	2	0	3
CCDC147 WILD-TYPE	31	48	28

'ZNF662 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.379 (Fisher's exact test), Q value = 0.77

Table S1087. Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ZNF662 MUTATED	2	1	0	0
ZNF662 WILD-TYPE	10	17	11	10

'ZNF662 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.282 (Fisher's exact test), Q value = 0.7

Table S1088. Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ZNF662 MUTATED	1	0	1	1	0
ZNF662 WILD-TYPE	11	10	6	6	15

'ZNF662 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 0.81

Table S1089. Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF662 MUTATED	1	10	0	0	2
ZNF662 WILD-TYPE	55	142	11	5	16

'ZNF662 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.138 (Fisher's exact test), Q value = 0.54

Table S1090. Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF662 MUTATED	3	0	5
ZNF662 WILD-TYPE	40	39	48

'ZNF662 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.807 (Fisher's exact test), Q value = 1

Table S1091. Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF662 MUTATED	3	5	4
ZNF662 WILD-TYPE	68	67	56

'ZNF662 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.131 (Fisher's exact test), Q value = 0.53

Table S1092. Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF662 MUTATED	1	8	2	1
ZNF662 WILD-TYPE	67	70	29	25

'ZNF662 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0635 (Fisher's exact test), Q value = 0.39

Table S1093. Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF662 MUTATED	7	5	1
ZNF662 WILD-TYPE	72	80	82

'ZNF662 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 6e-05 (Fisher's exact test), Q value = 0.0035

Table S1094. Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF662 MUTATED	0	0	2	6	5	0	0
ZNF662 WILD-TYPE	44	41	15	27	30	31	46

Figure S226. Get High-res Image Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF662 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.574 (Fisher's exact test), Q value = 0.9

Table S1095. Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF662 MUTATED	4	5	3
ZNF662 WILD-TYPE	65	74	89

'ZNF662 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.257 (Fisher's exact test), Q value = 0.68

Table S1096. Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF662 MUTATED	7	1	2	2
ZNF662 WILD-TYPE	66	42	77	43

'ZNF662 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.361 (Fisher's exact test), Q value = 0.77

Table S1097. Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZNF662 MUTATED	1	2	2
ZNF662 WILD-TYPE	28	17	62

'ZNF662 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0753 (Fisher's exact test), Q value = 0.43

Table S1098. Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZNF662 MUTATED	2	0	3
ZNF662 WILD-TYPE	31	48	28

'PSMC4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.349 (Fisher's exact test), Q value = 0.77

Table S1099. Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PSMC4 MUTATED	0	9	0	0	1
PSMC4 WILD-TYPE	56	143	11	5	17

'PSMC4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 0.81

Table S1100. Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PSMC4 MUTATED	2	0	3
PSMC4 WILD-TYPE	41	39	50

'PSMC4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.902 (Fisher's exact test), Q value = 1

Table S1101. Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PSMC4 MUTATED	2	3	3
PSMC4 WILD-TYPE	69	69	57

'PSMC4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.522 (Fisher's exact test), Q value = 0.87

Table S1102. Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PSMC4 MUTATED	1	4	2	1
PSMC4 WILD-TYPE	67	74	29	25

'PSMC4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 0.69

Table S1103. Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PSMC4 MUTATED	6	2	3
PSMC4 WILD-TYPE	73	83	80

'PSMC4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00807 (Fisher's exact test), Q value = 0.12

Table S1104. Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PSMC4 MUTATED	0	0	1	1	6	1	2
PSMC4 WILD-TYPE	44	41	16	32	29	30	44

Figure S227. Get High-res Image Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PSMC4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.72 (Fisher's exact test), Q value = 0.99

Table S1105. Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PSMC4 MUTATED	4	3	3
PSMC4 WILD-TYPE	65	76	89

'PSMC4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.177 (Fisher's exact test), Q value = 0.58

Table S1106. Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PSMC4 MUTATED	6	0	3	1
PSMC4 WILD-TYPE	67	43	76	44

'PSMC4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 0.53

Table S1107. Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
PSMC4 MUTATED	1	2	1
PSMC4 WILD-TYPE	28	17	63

'PSMC4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S1108. Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
PSMC4 MUTATED	2	1	1
PSMC4 WILD-TYPE	31	47	30

'CCDC160 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 0.97

Table S1109. Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
CCDC160 MUTATED	1	2	0	0
CCDC160 WILD-TYPE	11	16	11	10

'CCDC160 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.207 (Fisher's exact test), Q value = 0.6

Table S1110. Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
CCDC160 MUTATED	2	0	0	1	0
CCDC160 WILD-TYPE	10	10	7	6	15

'CCDC160 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.274 (Fisher's exact test), Q value = 0.7

Table S1111. Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CCDC160 MUTATED	0	10	0	0	1
CCDC160 WILD-TYPE	56	142	11	5	17

'CCDC160 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1112. Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CCDC160 MUTATED	1	1	2
CCDC160 WILD-TYPE	42	38	51

'CCDC160 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 0.7

Table S1113. Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CCDC160 MUTATED	6	2	2
CCDC160 WILD-TYPE	65	70	58

'CCDC160 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.602 (Fisher's exact test), Q value = 0.92

Table S1114. Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CCDC160 MUTATED	3	3	3	1
CCDC160 WILD-TYPE	65	75	28	25

'CCDC160 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.549 (Fisher's exact test), Q value = 0.89

Table S1115. Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CCDC160 MUTATED	4	5	2
CCDC160 WILD-TYPE	75	80	81

'CCDC160 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0263 (Fisher's exact test), Q value = 0.25

Table S1116. Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CCDC160 MUTATED	0	1	1	4	4	0	1
CCDC160 WILD-TYPE	44	40	16	29	31	31	45

Figure S228. Get High-res Image Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CCDC160 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.919 (Fisher's exact test), Q value = 1

Table S1117. Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CCDC160 MUTATED	3	4	3
CCDC160 WILD-TYPE	66	75	89

'CCDC160 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.164 (Fisher's exact test), Q value = 0.58

Table S1118. Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CCDC160 MUTATED	6	1	3	0
CCDC160 WILD-TYPE	67	42	76	45

'CCDC160 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.56 (Fisher's exact test), Q value = 0.89

Table S1119. Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CCDC160 MUTATED	0	1	2
CCDC160 WILD-TYPE	29	18	62

'CCDC160 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.355 (Fisher's exact test), Q value = 0.77

Table S1120. Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CCDC160 MUTATED	0	1	2
CCDC160 WILD-TYPE	33	47	29

'PPIL4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 0.77

Table S1121. Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
PPIL4 MUTATED	2	1	0	0
PPIL4 WILD-TYPE	10	17	11	10

'PPIL4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.285 (Fisher's exact test), Q value = 0.7

Table S1122. Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
PPIL4 MUTATED	1	0	1	1	0
PPIL4 WILD-TYPE	11	10	6	6	15

'PPIL4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.655 (Fisher's exact test), Q value = 0.96

Table S1123. Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PPIL4 MUTATED	1	9	0	0	1
PPIL4 WILD-TYPE	55	143	11	5	17

'PPIL4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.657 (Fisher's exact test), Q value = 0.96

Table S1124. Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PPIL4 MUTATED	3	1	4
PPIL4 WILD-TYPE	40	38	49

'PPIL4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1125. Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PPIL4 MUTATED	4	4	3
PPIL4 WILD-TYPE	67	68	57

'PPIL4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.176 (Fisher's exact test), Q value = 0.58

Table S1126. Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PPIL4 MUTATED	2	7	0	2
PPIL4 WILD-TYPE	66	71	31	24

'PPIL4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 0.53

Table S1127. Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PPIL4 MUTATED	6	4	1
PPIL4 WILD-TYPE	73	81	82

'PPIL4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00235 (Fisher's exact test), Q value = 0.053

Table S1128. Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PPIL4 MUTATED	2	0	1	6	2	0	0
PPIL4 WILD-TYPE	42	41	16	27	33	31	46

Figure S229. Get High-res Image Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PPIL4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.247 (Fisher's exact test), Q value = 0.67

Table S1129. Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PPIL4 MUTATED	3	6	2
PPIL4 WILD-TYPE	66	73	90

'PPIL4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0893 (Fisher's exact test), Q value = 0.46

Table S1130. Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PPIL4 MUTATED	7	1	1	2
PPIL4 WILD-TYPE	66	42	78	43

'PPIL4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.055 (Fisher's exact test), Q value = 0.36

Table S1131. Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
PPIL4 MUTATED	3	2	1
PPIL4 WILD-TYPE	26	17	63

'PPIL4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0348 (Fisher's exact test), Q value = 0.3

Table S1132. Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
PPIL4 MUTATED	4	0	2
PPIL4 WILD-TYPE	29	48	29

Figure S230. Get High-res Image Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CCDC144A MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.809 (Fisher's exact test), Q value = 1

Table S1133. Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
CCDC144A MUTATED	2	2	1	0
CCDC144A WILD-TYPE	10	16	10	10

'CCDC144A MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0937 (Fisher's exact test), Q value = 0.46

Table S1134. Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
CCDC144A MUTATED	2	0	2	1	0
CCDC144A WILD-TYPE	10	10	5	6	15

'CCDC144A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.558 (Fisher's exact test), Q value = 0.89

Table S1135. Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CCDC144A MUTATED	2	14	0	0	2
CCDC144A WILD-TYPE	54	138	11	5	16

'CCDC144A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.427 (Fisher's exact test), Q value = 0.79

Table S1136. Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CCDC144A MUTATED	3	1	5
CCDC144A WILD-TYPE	40	38	48

'CCDC144A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.846 (Fisher's exact test), Q value = 1

Table S1137. Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CCDC144A MUTATED	5	7	4
CCDC144A WILD-TYPE	66	65	56

'CCDC144A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.332 (Fisher's exact test), Q value = 0.74

Table S1138. Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CCDC144A MUTATED	5	7	4	0
CCDC144A WILD-TYPE	63	71	27	26

'CCDC144A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 0.91

Table S1139. Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CCDC144A MUTATED	7	7	4
CCDC144A WILD-TYPE	72	78	79

'CCDC144A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00395 (Fisher's exact test), Q value = 0.075

Table S1140. Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CCDC144A MUTATED	0	1	2	6	6	1	2
CCDC144A WILD-TYPE	44	40	15	27	29	30	44

Figure S231. Get High-res Image Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CCDC144A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.46 (Fisher's exact test), Q value = 0.82

Table S1141. Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CCDC144A MUTATED	4	8	5
CCDC144A WILD-TYPE	65	71	87

'CCDC144A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.639 (Fisher's exact test), Q value = 0.95

Table S1142. Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CCDC144A MUTATED	7	2	4	4
CCDC144A WILD-TYPE	66	41	75	41

'CCDC144A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.866 (Fisher's exact test), Q value = 1

Table S1143. Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CCDC144A MUTATED	1	1	5
CCDC144A WILD-TYPE	28	18	59

'CCDC144A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.289 (Fisher's exact test), Q value = 0.7

Table S1144. Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CCDC144A MUTATED	1	2	4
CCDC144A WILD-TYPE	32	46	27

'TUBGCP6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0396 (Fisher's exact test), Q value = 0.31

Table S1145. Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
TUBGCP6 MUTATED	0	17	1	0	2
TUBGCP6 WILD-TYPE	56	135	10	5	16

Figure S232. Get High-res Image Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'TUBGCP6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.178 (Fisher's exact test), Q value = 0.59

Table S1146. Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
TUBGCP6 MUTATED	2	2	8
TUBGCP6 WILD-TYPE	41	37	45

'TUBGCP6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.137 (Fisher's exact test), Q value = 0.54

Table S1147. Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
TUBGCP6 MUTATED	9	5	2
TUBGCP6 WILD-TYPE	62	67	58

'TUBGCP6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.294 (Fisher's exact test), Q value = 0.7

Table S1148. Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
TUBGCP6 MUTATED	5	4	5	2
TUBGCP6 WILD-TYPE	63	74	26	24

'TUBGCP6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.705 (Fisher's exact test), Q value = 0.98

Table S1149. Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
TUBGCP6 MUTATED	7	8	5
TUBGCP6 WILD-TYPE	72	77	78

'TUBGCP6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00087 (Fisher's exact test), Q value = 0.026

Table S1150. Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
TUBGCP6 MUTATED	0	1	2	6	7	0	4
TUBGCP6 WILD-TYPE	44	40	15	27	28	31	42

Figure S233. Get High-res Image Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TUBGCP6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.959 (Fisher's exact test), Q value = 1

Table S1151. Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
TUBGCP6 MUTATED	6	7	7
TUBGCP6 WILD-TYPE	63	72	85

'TUBGCP6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.149 (Fisher's exact test), Q value = 0.55

Table S1152. Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
TUBGCP6 MUTATED	10	1	7	2
TUBGCP6 WILD-TYPE	63	42	72	43

'TUBGCP6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1153. Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
TUBGCP6 MUTATED	2	2	6
TUBGCP6 WILD-TYPE	27	17	58

'TUBGCP6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.536 (Fisher's exact test), Q value = 0.88

Table S1154. Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
TUBGCP6 MUTATED	3	3	4
TUBGCP6 WILD-TYPE	30	45	27

'TTC39C MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 0.97

Table S1155. Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
TTC39C MUTATED	1	2	0	0
TTC39C WILD-TYPE	11	16	11	10

'TTC39C MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.206 (Fisher's exact test), Q value = 0.6

Table S1156. Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
TTC39C MUTATED	2	0	0	1	0
TTC39C WILD-TYPE	10	10	7	6	15

'TTC39C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.432 (Fisher's exact test), Q value = 0.79

Table S1157. Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
TTC39C MUTATED	0	6	0	0	1
TTC39C WILD-TYPE	56	146	11	5	17

'TTC39C MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.711 (Fisher's exact test), Q value = 0.98

Table S1158. Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
TTC39C MUTATED	3	3	1
TTC39C WILD-TYPE	68	69	59

'TTC39C MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.232 (Fisher's exact test), Q value = 0.64

Table S1159. Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
TTC39C MUTATED	2	2	3	0
TTC39C WILD-TYPE	66	76	28	26

'TTC39C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.408 (Fisher's exact test), Q value = 0.78

Table S1160. Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
TTC39C MUTATED	2	4	1
TTC39C WILD-TYPE	77	81	82

'TTC39C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0265 (Fisher's exact test), Q value = 0.25

Table S1161. Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
TTC39C MUTATED	0	0	0	2	4	0	1
TTC39C WILD-TYPE	44	41	17	31	31	31	45

Figure S234. Get High-res Image Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TTC39C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.289 (Fisher's exact test), Q value = 0.7

Table S1162. Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
TTC39C MUTATED	1	4	1
TTC39C WILD-TYPE	68	75	91

'TTC39C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.331 (Fisher's exact test), Q value = 0.74

Table S1163. Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
TTC39C MUTATED	4	0	1	1
TTC39C WILD-TYPE	69	43	78	44

'COL8A1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.163 (Fisher's exact test), Q value = 0.58

Table S1164. Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
COL8A1 MUTATED	2	0	0	1
COL8A1 WILD-TYPE	10	18	11	9

'COL8A1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.139 (Fisher's exact test), Q value = 0.54

Table S1165. Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
COL8A1 MUTATED	0	0	2	0	1
COL8A1 WILD-TYPE	12	10	5	7	14

'COL8A1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 0.58

Table S1166. Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
COL8A1 MUTATED	0	8	0	0	2
COL8A1 WILD-TYPE	56	144	11	5	16

'COL8A1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.443 (Fisher's exact test), Q value = 0.81

Table S1167. Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
COL8A1 MUTATED	2	0	3
COL8A1 WILD-TYPE	41	39	50

'COL8A1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0189 (Fisher's exact test), Q value = 0.21

Table S1168. Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
COL8A1 MUTATED	2	7	0
COL8A1 WILD-TYPE	69	65	60

Figure S235. Get High-res Image Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'COL8A1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.312 (Fisher's exact test), Q value = 0.72

Table S1169. Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
COL8A1 MUTATED	1	5	1	2
COL8A1 WILD-TYPE	67	73	30	24

'COL8A1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.262 (Fisher's exact test), Q value = 0.69

Table S1170. Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
COL8A1 MUTATED	4	5	1
COL8A1 WILD-TYPE	75	80	82

'COL8A1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0136 (Fisher's exact test), Q value = 0.18

Table S1171. Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
COL8A1 MUTATED	0	1	1	5	2	1	0
COL8A1 WILD-TYPE	44	40	16	28	33	30	46

Figure S236. Get High-res Image Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'COL8A1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.142 (Fisher's exact test), Q value = 0.55

Table S1172. Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
COL8A1 MUTATED	4	5	1
COL8A1 WILD-TYPE	65	74	91

'COL8A1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0795 (Fisher's exact test), Q value = 0.43

Table S1173. Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
COL8A1 MUTATED	7	1	1	1
COL8A1 WILD-TYPE	66	42	78	44

'COL8A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0422 (Fisher's exact test), Q value = 0.32

Table S1174. Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
COL8A1 MUTATED	2	2	0
COL8A1 WILD-TYPE	27	17	64

Figure S237. Get High-res Image Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'COL8A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.169 (Fisher's exact test), Q value = 0.58

Table S1175. Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
COL8A1 MUTATED	2	0	2
COL8A1 WILD-TYPE	31	48	29

'PER3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.148 (Fisher's exact test), Q value = 0.55

Table S1176. Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PER3 MUTATED	0	10	0	0	2
PER3 WILD-TYPE	56	142	11	5	16

'PER3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 0.53

Table S1177. Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PER3 MUTATED	2	0	5
PER3 WILD-TYPE	41	39	48

'PER3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.338 (Fisher's exact test), Q value = 0.75

Table S1178. Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PER3 MUTATED	2	6	3
PER3 WILD-TYPE	69	66	57

'PER3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.211 (Fisher's exact test), Q value = 0.61

Table S1179. Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PER3 MUTATED	1	7	2	1
PER3 WILD-TYPE	67	71	29	25

'PER3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0679 (Fisher's exact test), Q value = 0.4

Table S1180. Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PER3 MUTATED	7	4	1
PER3 WILD-TYPE	72	81	82

'PER3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00064 (Fisher's exact test), Q value = 0.02

Table S1181. Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PER3 MUTATED	0	0	1	4	6	0	1
PER3 WILD-TYPE	44	41	16	29	29	31	45

Figure S238. Get High-res Image Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PER3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.683 (Fisher's exact test), Q value = 0.97

Table S1182. Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PER3 MUTATED	3	5	3
PER3 WILD-TYPE	66	74	89

'PER3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0819 (Fisher's exact test), Q value = 0.44

Table S1183. Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PER3 MUTATED	7	0	2	2
PER3 WILD-TYPE	66	43	77	43

'PER3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 0.53

Table S1184. Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
PER3 MUTATED	1	2	1
PER3 WILD-TYPE	28	17	63

'PER3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.167 (Fisher's exact test), Q value = 0.58

Table S1185. Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
PER3 MUTATED	2	0	2
PER3 WILD-TYPE	31	48	29

'MGA MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.325 (Fisher's exact test), Q value = 0.74

Table S1186. Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
MGA MUTATED	3	2	0	1
MGA WILD-TYPE	9	16	11	9

'MGA MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.365 (Fisher's exact test), Q value = 0.77

Table S1187. Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
MGA MUTATED	2	0	1	2	1
MGA WILD-TYPE	10	10	6	5	14

'MGA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.548 (Fisher's exact test), Q value = 0.89

Table S1188. Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MGA MUTATED	3	20	1	0	2
MGA WILD-TYPE	53	132	10	5	16

'MGA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S1189. Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MGA MUTATED	5	3	5
MGA WILD-TYPE	38	36	48

'MGA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.671 (Fisher's exact test), Q value = 0.97

Table S1190. Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MGA MUTATED	6	9	8
MGA WILD-TYPE	65	63	52

'MGA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.163 (Fisher's exact test), Q value = 0.58

Table S1191. Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MGA MUTATED	4	11	6	2
MGA WILD-TYPE	64	67	25	24

'MGA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0274 (Fisher's exact test), Q value = 0.26

Table S1192. Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MGA MUTATED	12	11	3
MGA WILD-TYPE	67	74	80

Figure S239. Get High-res Image Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'MGA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00224 (Fisher's exact test), Q value = 0.052

Table S1193. Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MGA MUTATED	3	1	3	7	9	1	2
MGA WILD-TYPE	41	40	14	26	26	30	44

Figure S240. Get High-res Image Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MGA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 0.53

Table S1194. Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MGA MUTATED	10	9	5
MGA WILD-TYPE	59	70	87

'MGA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00924 (Fisher's exact test), Q value = 0.13

Table S1195. Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MGA MUTATED	14	1	4	5
MGA WILD-TYPE	59	42	75	40

Figure S241. Get High-res Image Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'MGA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0967 (Fisher's exact test), Q value = 0.47

Table S1196. Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MGA MUTATED	5	3	3
MGA WILD-TYPE	24	16	61

'MGA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.042 (Fisher's exact test), Q value = 0.32

Table S1197. Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MGA MUTATED	5	1	5
MGA WILD-TYPE	28	47	26

Figure S242. Get High-res Image Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'GPRASP1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.289 (Fisher's exact test), Q value = 0.7

Table S1198. Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
GPRASP1 MUTATED	3	1	1	0
GPRASP1 WILD-TYPE	9	17	10	10

'GPRASP1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0452 (Fisher's exact test), Q value = 0.33

Table S1199. Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
GPRASP1 MUTATED	1	0	2	2	0
GPRASP1 WILD-TYPE	11	10	5	5	15

Figure S243. Get High-res Image Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'GPRASP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 0.51

Table S1200. Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
GPRASP1 MUTATED	1	19	0	0	1
GPRASP1 WILD-TYPE	55	133	11	5	17

'GPRASP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.628 (Fisher's exact test), Q value = 0.95

Table S1201. Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
GPRASP1 MUTATED	3	2	6
GPRASP1 WILD-TYPE	40	37	47

'GPRASP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.712 (Fisher's exact test), Q value = 0.98

Table S1202. Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
GPRASP1 MUTATED	6	8	4
GPRASP1 WILD-TYPE	65	64	56

'GPRASP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.43 (Fisher's exact test), Q value = 0.79

Table S1203. Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
GPRASP1 MUTATED	4	9	4	1
GPRASP1 WILD-TYPE	64	69	27	25

'GPRASP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1204. Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
GPRASP1 MUTATED	6	7	7
GPRASP1 WILD-TYPE	73	78	76

'GPRASP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.113 (Fisher's exact test), Q value = 0.51

Table S1205. Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
GPRASP1 MUTATED	1	1	1	6	5	2	4
GPRASP1 WILD-TYPE	43	40	16	27	30	29	42

'GPRASP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 0.82

Table S1206. Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
GPRASP1 MUTATED	4	9	7
GPRASP1 WILD-TYPE	65	70	85

'GPRASP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.426 (Fisher's exact test), Q value = 0.79

Table S1207. Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
GPRASP1 MUTATED	9	2	7	2
GPRASP1 WILD-TYPE	64	41	72	43

'GPRASP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S1208. Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
GPRASP1 MUTATED	1	2	4
GPRASP1 WILD-TYPE	28	17	60

'GPRASP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1209. Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
GPRASP1 MUTATED	2	3	2
GPRASP1 WILD-TYPE	31	45	29

'PPM1D MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.379 (Fisher's exact test), Q value = 0.77

Table S1210. Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
PPM1D MUTATED	2	1	0	0
PPM1D WILD-TYPE	10	17	11	10

'PPM1D MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 0.7

Table S1211. Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
PPM1D MUTATED	1	0	1	1	0
PPM1D WILD-TYPE	11	10	6	6	15

'PPM1D MUTATION STATUS' versus 'CN_CNMF'

P value = 0.273 (Fisher's exact test), Q value = 0.7

Table S1212. Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PPM1D MUTATED	0	10	0	0	1
PPM1D WILD-TYPE	56	142	11	5	17

'PPM1D MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.151 (Fisher's exact test), Q value = 0.56

Table S1213. Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PPM1D MUTATED	0	1	4
PPM1D WILD-TYPE	43	38	49

'PPM1D MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 0.97

Table S1214. Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PPM1D MUTATED	4	5	2
PPM1D WILD-TYPE	67	67	58

'PPM1D MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.749 (Fisher's exact test), Q value = 1

Table S1215. Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PPM1D MUTATED	3	4	3	1
PPM1D WILD-TYPE	65	74	28	25

'PPM1D MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.369 (Fisher's exact test), Q value = 0.77

Table S1216. Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PPM1D MUTATED	3	6	2
PPM1D WILD-TYPE	76	79	81

'PPM1D MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0422 (Fisher's exact test), Q value = 0.32

Table S1217. Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PPM1D MUTATED	0	1	0	3	5	1	1
PPM1D WILD-TYPE	44	40	17	30	30	30	45

Figure S244. Get High-res Image Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PPM1D MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.718 (Fisher's exact test), Q value = 0.98

Table S1218. Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PPM1D MUTATED	4	3	3
PPM1D WILD-TYPE	65	76	89

'PPM1D MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.029 (Fisher's exact test), Q value = 0.27

Table S1219. Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PPM1D MUTATED	7	2	1	0
PPM1D WILD-TYPE	66	41	78	45

Figure S245. Get High-res Image Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PPM1D MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 0.95

Table S1220. Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
PPM1D MUTATED	2	0	2
PPM1D WILD-TYPE	27	19	62

'PPM1D MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.813 (Fisher's exact test), Q value = 1

Table S1221. Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
PPM1D MUTATED	2	1	1
PPM1D WILD-TYPE	31	47	30

'ZNF674 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.419 (Fisher's exact test), Q value = 0.79

Table S1222. Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF674 MUTATED	1	11	0	0	2
ZNF674 WILD-TYPE	55	141	11	5	16

'ZNF674 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S1223. Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF674 MUTATED	2	1	3
ZNF674 WILD-TYPE	41	38	50

'ZNF674 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.659 (Fisher's exact test), Q value = 0.96

Table S1224. Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF674 MUTATED	3	4	5
ZNF674 WILD-TYPE	68	68	55

'ZNF674 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.178 (Fisher's exact test), Q value = 0.59

Table S1225. Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF674 MUTATED	2	7	3	0
ZNF674 WILD-TYPE	66	71	28	26

'ZNF674 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.2 (Fisher's exact test), Q value = 0.6

Table S1226. Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF674 MUTATED	7	5	2
ZNF674 WILD-TYPE	72	80	81

'ZNF674 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00207 (Fisher's exact test), Q value = 0.049

Table S1227. Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF674 MUTATED	0	1	2	4	6	0	1
ZNF674 WILD-TYPE	44	40	15	29	29	31	45

Figure S246. Get High-res Image Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF674 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 0.55

Table S1228. Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF674 MUTATED	4	7	2
ZNF674 WILD-TYPE	65	72	90

'ZNF674 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.373 (Fisher's exact test), Q value = 0.77

Table S1229. Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF674 MUTATED	7	1	3	2
ZNF674 WILD-TYPE	66	42	76	43

'ZNF674 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 0.59

Table S1230. Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZNF674 MUTATED	0	2	2
ZNF674 WILD-TYPE	29	17	62

'ZNF674 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.688 (Fisher's exact test), Q value = 0.97

Table S1231. Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZNF674 MUTATED	1	1	2
ZNF674 WILD-TYPE	32	47	29

'LIMK2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.201 (Fisher's exact test), Q value = 0.6

Table S1232. Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
LIMK2 MUTATED	2	0	1	0
LIMK2 WILD-TYPE	10	18	10	10

'LIMK2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.452 (Fisher's exact test), Q value = 0.81

Table S1233. Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
LIMK2 MUTATED	0	0	1	1	1
LIMK2 WILD-TYPE	12	10	6	6	14

'LIMK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.62 (Fisher's exact test), Q value = 0.94

Table S1234. Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
LIMK2 MUTATED	1	10	0	0	1
LIMK2 WILD-TYPE	55	142	11	5	17

'LIMK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 0.77

Table S1235. Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
LIMK2 MUTATED	2	3	1
LIMK2 WILD-TYPE	41	36	52

'LIMK2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.259 (Fisher's exact test), Q value = 0.68

Table S1236. Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
LIMK2 MUTATED	4	6	1
LIMK2 WILD-TYPE	67	66	59

'LIMK2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.216 (Fisher's exact test), Q value = 0.62

Table S1237. Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
LIMK2 MUTATED	3	4	4	0
LIMK2 WILD-TYPE	65	74	27	26

'LIMK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.568 (Fisher's exact test), Q value = 0.89

Table S1238. Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
LIMK2 MUTATED	3	3	6
LIMK2 WILD-TYPE	76	82	77

'LIMK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.307 (Fisher's exact test), Q value = 0.72

Table S1239. Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
LIMK2 MUTATED	1	0	1	2	2	1	5
LIMK2 WILD-TYPE	43	41	16	31	33	30	41

'LIMK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 0.85

Table S1240. Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
LIMK2 MUTATED	4	2	6
LIMK2 WILD-TYPE	65	77	86

'LIMK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.393 (Fisher's exact test), Q value = 0.77

Table S1241. Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
LIMK2 MUTATED	3	1	7	1
LIMK2 WILD-TYPE	70	42	72	44

'LIMK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1242. Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
LIMK2 MUTATED	1	1	3
LIMK2 WILD-TYPE	28	18	61

'LIMK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.514 (Fisher's exact test), Q value = 0.87

Table S1243. Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
LIMK2 MUTATED	2	3	0
LIMK2 WILD-TYPE	31	45	31

'ZNF606 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 0.53

Table S1244. Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ZNF606 MUTATED	3	1	0	0
ZNF606 WILD-TYPE	9	17	11	10

'ZNF606 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0915 (Fisher's exact test), Q value = 0.46

Table S1245. Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ZNF606 MUTATED	1	0	1	2	0
ZNF606 WILD-TYPE	11	10	6	5	15

'ZNF606 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0716 (Fisher's exact test), Q value = 0.42

Table S1246. Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF606 MUTATED	0	14	0	0	2
ZNF606 WILD-TYPE	56	138	11	5	16

'ZNF606 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.19 (Fisher's exact test), Q value = 0.59

Table S1247. Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF606 MUTATED	1	1	6
ZNF606 WILD-TYPE	42	38	47

'ZNF606 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.737 (Fisher's exact test), Q value = 0.99

Table S1248. Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF606 MUTATED	5	6	3
ZNF606 WILD-TYPE	66	66	57

'ZNF606 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.719 (Fisher's exact test), Q value = 0.99

Table S1249. Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF606 MUTATED	3	7	2	2
ZNF606 WILD-TYPE	65	71	29	24

'ZNF606 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.809 (Fisher's exact test), Q value = 1

Table S1250. Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF606 MUTATED	6	6	4
ZNF606 WILD-TYPE	73	79	79

'ZNF606 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00239 (Fisher's exact test), Q value = 0.053

Table S1251. Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF606 MUTATED	1	0	2	6	5	0	2
ZNF606 WILD-TYPE	43	41	15	27	30	31	44

Figure S247. Get High-res Image Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF606 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S1252. Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF606 MUTATED	4	6	5
ZNF606 WILD-TYPE	65	73	87

'ZNF606 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.488 (Fisher's exact test), Q value = 0.85

Table S1253. Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF606 MUTATED	7	1	5	2
ZNF606 WILD-TYPE	66	42	74	43

'ZNF606 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1254. Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZNF606 MUTATED	1	1	3
ZNF606 WILD-TYPE	28	18	61

'ZNF606 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 0.92

Table S1255. Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZNF606 MUTATED	2	1	2
ZNF606 WILD-TYPE	31	47	29

'SFRP4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.378 (Fisher's exact test), Q value = 0.77

Table S1256. Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
SFRP4 MUTATED	2	1	0	0
SFRP4 WILD-TYPE	10	17	11	10

'SFRP4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 0.7

Table S1257. Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
SFRP4 MUTATED	1	0	1	1	0
SFRP4 WILD-TYPE	11	10	6	6	15

'SFRP4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.2 (Fisher's exact test), Q value = 0.6

Table S1258. Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SFRP4 MUTATED	0	6	0	0	2
SFRP4 WILD-TYPE	56	146	11	5	16

'SFRP4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.46 (Fisher's exact test), Q value = 0.82

Table S1259. Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SFRP4 MUTATED	0	2	2
SFRP4 WILD-TYPE	43	37	51

'SFRP4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.677 (Fisher's exact test), Q value = 0.97

Table S1260. Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SFRP4 MUTATED	1	3	2
SFRP4 WILD-TYPE	70	69	58

'SFRP4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0947 (Fisher's exact test), Q value = 0.46

Table S1261. Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SFRP4 MUTATED	0	5	0	1
SFRP4 WILD-TYPE	68	73	31	25

'SFRP4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.181 (Fisher's exact test), Q value = 0.59

Table S1262. Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SFRP4 MUTATED	5	2	1
SFRP4 WILD-TYPE	74	83	82

'SFRP4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0603 (Fisher's exact test), Q value = 0.38

Table S1263. Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SFRP4 MUTATED	1	0	0	2	4	1	0
SFRP4 WILD-TYPE	43	41	17	31	31	30	46

'SFRP4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.122 (Fisher's exact test), Q value = 0.52

Table S1264. Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SFRP4 MUTATED	1	5	1
SFRP4 WILD-TYPE	68	74	91

'SFRP4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.952 (Fisher's exact test), Q value = 1

Table S1265. Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SFRP4 MUTATED	3	1	2	1
SFRP4 WILD-TYPE	70	42	77	44

'TXNRD1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 0.97

Table S1266. Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
TXNRD1 MUTATED	1	2	0	0
TXNRD1 WILD-TYPE	11	16	11	10

'TXNRD1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 0.6

Table S1267. Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
TXNRD1 MUTATED	2	0	0	1	0
TXNRD1 WILD-TYPE	10	10	7	6	15

'TXNRD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.701 (Fisher's exact test), Q value = 0.98

Table S1268. Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
TXNRD1 MUTATED	1	6	0	0	1
TXNRD1 WILD-TYPE	55	146	11	5	17

'TXNRD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.384 (Fisher's exact test), Q value = 0.77

Table S1269. Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
TXNRD1 MUTATED	1	0	3
TXNRD1 WILD-TYPE	42	39	50

'TXNRD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 0.85

Table S1270. Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
TXNRD1 MUTATED	2	2	4
TXNRD1 WILD-TYPE	69	70	56

'TXNRD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.302 (Fisher's exact test), Q value = 0.71

Table S1271. Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
TXNRD1 MUTATED	2	3	3	0
TXNRD1 WILD-TYPE	66	75	28	26

'TXNRD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.363 (Fisher's exact test), Q value = 0.77

Table S1272. Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
TXNRD1 MUTATED	4	3	1
TXNRD1 WILD-TYPE	75	82	82

'TXNRD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0361 (Fisher's exact test), Q value = 0.3

Table S1273. Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
TXNRD1 MUTATED	1	0	1	3	3	0	0
TXNRD1 WILD-TYPE	43	41	16	30	32	31	46

Figure S248. Get High-res Image Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TXNRD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0556 (Fisher's exact test), Q value = 0.36

Table S1274. Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
TXNRD1 MUTATED	1	6	1
TXNRD1 WILD-TYPE	68	73	91

'TXNRD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.17 (Fisher's exact test), Q value = 0.58

Table S1275. Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
TXNRD1 MUTATED	4	0	1	3
TXNRD1 WILD-TYPE	69	43	78	42

'LETMD1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 0.77

Table S1276. Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
LETMD1 MUTATED	2	1	0	0
LETMD1 WILD-TYPE	10	17	11	10

'LETMD1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.284 (Fisher's exact test), Q value = 0.7

Table S1277. Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
LETMD1 MUTATED	1	0	1	1	0
LETMD1 WILD-TYPE	11	10	6	6	15

'LETMD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.74 (Fisher's exact test), Q value = 0.99

Table S1278. Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
LETMD1 MUTATED	1	4	0	0	1
LETMD1 WILD-TYPE	55	148	11	5	17

'LETMD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1279. Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
LETMD1 MUTATED	2	2	1
LETMD1 WILD-TYPE	69	70	59

'LETMD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.732 (Fisher's exact test), Q value = 0.99

Table S1280. Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
LETMD1 MUTATED	1	3	1	0
LETMD1 WILD-TYPE	67	75	30	26

'LETMD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 0.53

Table S1281. Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
LETMD1 MUTATED	2	4	0
LETMD1 WILD-TYPE	77	81	83

'LETMD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00391 (Fisher's exact test), Q value = 0.075

Table S1282. Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
LETMD1 MUTATED	0	0	0	4	2	0	0
LETMD1 WILD-TYPE	44	41	17	29	33	31	46

Figure S249. Get High-res Image Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'LETMD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0643 (Fisher's exact test), Q value = 0.39

Table S1283. Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
LETMD1 MUTATED	2	4	0
LETMD1 WILD-TYPE	67	75	92

'LETMD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.134 (Fisher's exact test), Q value = 0.53

Table S1284. Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
LETMD1 MUTATED	4	1	0	1
LETMD1 WILD-TYPE	69	42	79	44

'ZNF721 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1285. Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ZNF721 MUTATED	1	1	1	0
ZNF721 WILD-TYPE	11	17	10	10

'ZNF721 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0774 (Fisher's exact test), Q value = 0.43

Table S1286. Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ZNF721 MUTATED	1	0	2	0	0
ZNF721 WILD-TYPE	11	10	5	7	15

'ZNF721 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.135 (Fisher's exact test), Q value = 0.53

Table S1287. Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF721 MUTATED	0	11	0	0	2
ZNF721 WILD-TYPE	56	141	11	5	16

'ZNF721 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.629 (Fisher's exact test), Q value = 0.95

Table S1288. Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF721 MUTATED	2	1	4
ZNF721 WILD-TYPE	41	38	49

'ZNF721 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 0.82

Table S1289. Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF721 MUTATED	3	6	2
ZNF721 WILD-TYPE	68	66	58

'ZNF721 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.202 (Fisher's exact test), Q value = 0.6

Table S1290. Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF721 MUTATED	1	5	3	2
ZNF721 WILD-TYPE	67	73	28	24

'ZNF721 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.52 (Fisher's exact test), Q value = 0.87

Table S1291. Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF721 MUTATED	6	4	3
ZNF721 WILD-TYPE	73	81	80

'ZNF721 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00526 (Fisher's exact test), Q value = 0.09

Table S1292. Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF721 MUTATED	0	0	1	3	6	2	1
ZNF721 WILD-TYPE	44	41	16	30	29	29	45

Figure S250. Get High-res Image Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF721 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.462 (Fisher's exact test), Q value = 0.82

Table S1293. Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF721 MUTATED	3	6	3
ZNF721 WILD-TYPE	66	73	89

'ZNF721 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.286 (Fisher's exact test), Q value = 0.7

Table S1294. Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF721 MUTATED	7	1	3	1
ZNF721 WILD-TYPE	66	42	76	44

'ZNF721 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.188 (Fisher's exact test), Q value = 0.59

Table S1295. Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZNF721 MUTATED	0	2	2
ZNF721 WILD-TYPE	29	17	62

'ZNF721 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1296. Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZNF721 MUTATED	1	2	1
ZNF721 WILD-TYPE	32	46	30

'RASSF9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 0.77

Table S1297. Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
RASSF9 MUTATED	0	7	0	0	1
RASSF9 WILD-TYPE	56	145	11	5	17

'RASSF9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S1298. Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
RASSF9 MUTATED	1	0	2
RASSF9 WILD-TYPE	42	39	51

'RASSF9 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 0.77

Table S1299. Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
RASSF9 MUTATED	1	4	2
RASSF9 WILD-TYPE	70	68	58

'RASSF9 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.708 (Fisher's exact test), Q value = 0.98

Table S1300. Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
RASSF9 MUTATED	2	3	2	0
RASSF9 WILD-TYPE	66	75	29	26

'RASSF9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.64 (Fisher's exact test), Q value = 0.95

Table S1301. Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
RASSF9 MUTATED	4	3	2
RASSF9 WILD-TYPE	75	82	81

'RASSF9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0479 (Fisher's exact test), Q value = 0.33

Table S1302. Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
RASSF9 MUTATED	0	1	0	3	4	0	1
RASSF9 WILD-TYPE	44	40	17	30	31	31	45

Figure S251. Get High-res Image Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RASSF9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.544 (Fisher's exact test), Q value = 0.88

Table S1303. Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
RASSF9 MUTATED	1	4	3
RASSF9 WILD-TYPE	68	75	89

'RASSF9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.924 (Fisher's exact test), Q value = 1

Table S1304. Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
RASSF9 MUTATED	2	2	3	1
RASSF9 WILD-TYPE	71	41	76	44

'AGXT2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.629 (Fisher's exact test), Q value = 0.95

Table S1305. Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
AGXT2 MUTATED	2	1	0	1
AGXT2 WILD-TYPE	10	17	11	9

'AGXT2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S1306. Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
AGXT2 MUTATED	1	0	1	1	1
AGXT2 WILD-TYPE	11	10	6	6	14

'AGXT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.159 (Fisher's exact test), Q value = 0.57

Table S1307. Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
AGXT2 MUTATED	0	9	0	0	2
AGXT2 WILD-TYPE	56	143	11	5	16

'AGXT2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.732 (Fisher's exact test), Q value = 0.99

Table S1308. Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
AGXT2 MUTATED	1	1	3
AGXT2 WILD-TYPE	42	38	50

'AGXT2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S1309. Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
AGXT2 MUTATED	3	3	4
AGXT2 WILD-TYPE	68	69	56

'AGXT2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.652 (Fisher's exact test), Q value = 0.96

Table S1310. Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
AGXT2 MUTATED	2	6	1	1
AGXT2 WILD-TYPE	66	72	30	25

'AGXT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.17 (Fisher's exact test), Q value = 0.58

Table S1311. Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
AGXT2 MUTATED	4	6	1
AGXT2 WILD-TYPE	75	79	82

'AGXT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00682 (Fisher's exact test), Q value = 0.11

Table S1312. Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
AGXT2 MUTATED	0	1	0	4	5	0	1
AGXT2 WILD-TYPE	44	40	17	29	30	31	45

Figure S252. Get High-res Image Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'AGXT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 0.73

Table S1313. Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
AGXT2 MUTATED	1	5	3
AGXT2 WILD-TYPE	68	74	89

'AGXT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.571 (Fisher's exact test), Q value = 0.89

Table S1314. Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
AGXT2 MUTATED	5	1	2	1
AGXT2 WILD-TYPE	68	42	77	44

'AGXT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.564 (Fisher's exact test), Q value = 0.89

Table S1315. Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
AGXT2 MUTATED	0	1	2
AGXT2 WILD-TYPE	29	18	62

'AGXT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.357 (Fisher's exact test), Q value = 0.77

Table S1316. Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
AGXT2 MUTATED	0	1	2
AGXT2 WILD-TYPE	33	47	29

'MECOM MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.535 (Fisher's exact test), Q value = 0.88

Table S1317. Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
MECOM MUTATED	2	2	0	0
MECOM WILD-TYPE	10	16	11	10

'MECOM MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0471 (Fisher's exact test), Q value = 0.33

Table S1318. Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
MECOM MUTATED	2	0	0	2	0
MECOM WILD-TYPE	10	10	7	5	15

Figure S253. Get High-res Image Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'MECOM MUTATION STATUS' versus 'CN_CNMF'

P value = 0.148 (Fisher's exact test), Q value = 0.55

Table S1319. Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MECOM MUTATED	0	10	0	0	2
MECOM WILD-TYPE	56	142	11	5	16

'MECOM MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.557 (Fisher's exact test), Q value = 0.89

Table S1320. Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MECOM MUTATED	1	2	4
MECOM WILD-TYPE	42	37	49

'MECOM MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.745 (Fisher's exact test), Q value = 1

Table S1321. Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MECOM MUTATED	5	3	3
MECOM WILD-TYPE	66	69	57

'MECOM MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.396 (Fisher's exact test), Q value = 0.77

Table S1322. Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MECOM MUTATED	3	6	0	2
MECOM WILD-TYPE	65	72	31	24

'MECOM MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 0.8

Table S1323. Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MECOM MUTATED	2	6	4
MECOM WILD-TYPE	77	79	79

'MECOM MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.257 (Fisher's exact test), Q value = 0.68

Table S1324. Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MECOM MUTATED	0	1	1	4	2	2	2
MECOM WILD-TYPE	44	40	16	29	33	29	44

'MECOM MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.313 (Fisher's exact test), Q value = 0.72

Table S1325. Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MECOM MUTATED	1	4	6
MECOM WILD-TYPE	68	75	86

'MECOM MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.657 (Fisher's exact test), Q value = 0.96

Table S1326. Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MECOM MUTATED	5	1	4	1
MECOM WILD-TYPE	68	42	75	44

'MECOM MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1327. Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MECOM MUTATED	1	1	4
MECOM WILD-TYPE	28	18	60

'MECOM MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1328. Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MECOM MUTATED	2	3	1
MECOM WILD-TYPE	31	45	30

'ATP6V1C2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.197 (Fisher's exact test), Q value = 0.59

Table S1329. Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ATP6V1C2 MUTATED	0	11	0	0	1
ATP6V1C2 WILD-TYPE	56	141	11	5	17

'ATP6V1C2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.51 (Fisher's exact test), Q value = 0.86

Table S1330. Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ATP6V1C2 MUTATED	1	1	4
ATP6V1C2 WILD-TYPE	42	38	49

'ATP6V1C2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.716 (Fisher's exact test), Q value = 0.98

Table S1331. Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ATP6V1C2 MUTATED	3	5	2
ATP6V1C2 WILD-TYPE	68	67	58

'ATP6V1C2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.405 (Fisher's exact test), Q value = 0.78

Table S1332. Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ATP6V1C2 MUTATED	4	3	3	0
ATP6V1C2 WILD-TYPE	64	75	28	26

'ATP6V1C2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 0.93

Table S1333. Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ATP6V1C2 MUTATED	3	6	3
ATP6V1C2 WILD-TYPE	76	79	80

'ATP6V1C2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0435 (Fisher's exact test), Q value = 0.32

Table S1334. Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ATP6V1C2 MUTATED	0	3	0	3	4	2	0
ATP6V1C2 WILD-TYPE	44	38	17	30	31	29	46

Figure S254. Get High-res Image Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ATP6V1C2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 0.79

Table S1335. Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ATP6V1C2 MUTATED	2	6	4
ATP6V1C2 WILD-TYPE	67	73	88

'ATP6V1C2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.483 (Fisher's exact test), Q value = 0.84

Table S1336. Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ATP6V1C2 MUTATED	6	1	4	1
ATP6V1C2 WILD-TYPE	67	42	75	44

'ATP6V1C2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1337. Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ATP6V1C2 MUTATED	1	1	3
ATP6V1C2 WILD-TYPE	28	18	61

'ATP6V1C2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.135 (Fisher's exact test), Q value = 0.53

Table S1338. Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ATP6V1C2 MUTATED	0	2	3
ATP6V1C2 WILD-TYPE	33	46	28

'DYM MUTATION STATUS' versus 'CN_CNMF'

P value = 0.271 (Fisher's exact test), Q value = 0.7

Table S1339. Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
DYM MUTATED	0	10	0	0	0
DYM WILD-TYPE	56	142	11	5	18

'DYM MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.282 (Fisher's exact test), Q value = 0.7

Table S1340. Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
DYM MUTATED	2	0	4
DYM WILD-TYPE	41	39	49

'DYM MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.912 (Fisher's exact test), Q value = 1

Table S1341. Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
DYM MUTATED	3	4	2
DYM WILD-TYPE	68	68	58

'DYM MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.158 (Fisher's exact test), Q value = 0.57

Table S1342. Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
DYM MUTATED	1	3	3	2
DYM WILD-TYPE	67	75	28	24

'DYM MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.722 (Fisher's exact test), Q value = 0.99

Table S1343. Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
DYM MUTATED	4	4	2
DYM WILD-TYPE	75	81	81

'DYM MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00379 (Fisher's exact test), Q value = 0.074

Table S1344. Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
DYM MUTATED	0	0	2	4	3	1	0
DYM WILD-TYPE	44	41	15	29	32	30	46

Figure S255. Get High-res Image Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'DYM MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1345. Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
DYM MUTATED	3	3	3
DYM WILD-TYPE	66	76	89

'DYM MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.101 (Fisher's exact test), Q value = 0.48

Table S1346. Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
DYM MUTATED	5	0	1	3
DYM WILD-TYPE	68	43	78	42

'DYM MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.807 (Fisher's exact test), Q value = 1

Table S1347. Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
DYM MUTATED	1	1	2
DYM WILD-TYPE	28	18	62

'DYM MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.167 (Fisher's exact test), Q value = 0.58

Table S1348. Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
DYM MUTATED	2	0	2
DYM WILD-TYPE	31	48	29

'TAB3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 0.53

Table S1349. Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
TAB3 MUTATED	3	1	0	0
TAB3 WILD-TYPE	9	17	11	10

'TAB3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0943 (Fisher's exact test), Q value = 0.46

Table S1350. Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
TAB3 MUTATED	1	0	1	2	0
TAB3 WILD-TYPE	11	10	6	5	15

'TAB3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0454 (Fisher's exact test), Q value = 0.33

Table S1351. Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
TAB3 MUTATED	0	17	0	0	1
TAB3 WILD-TYPE	56	135	11	5	17

Figure S256. Get High-res Image Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'TAB3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 0.7

Table S1352. Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
TAB3 MUTATED	2	2	7
TAB3 WILD-TYPE	41	37	46

'TAB3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 0.98

Table S1353. Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
TAB3 MUTATED	5	5	2
TAB3 WILD-TYPE	66	67	58

'TAB3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.736 (Fisher's exact test), Q value = 0.99

Table S1354. Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
TAB3 MUTATED	3	5	3	1
TAB3 WILD-TYPE	65	73	28	25

'TAB3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0499 (Fisher's exact test), Q value = 0.34

Table S1355. Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
TAB3 MUTATED	4	11	3
TAB3 WILD-TYPE	75	74	80

Figure S257. Get High-res Image Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'TAB3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 4e-05 (Fisher's exact test), Q value = 0.0026

Table S1356. Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
TAB3 MUTATED	0	1	1	10	4	0	2
TAB3 WILD-TYPE	44	40	16	23	31	31	44

Figure S258. Get High-res Image Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TAB3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 0.82

Table S1357. Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
TAB3 MUTATED	3	7	8
TAB3 WILD-TYPE	66	72	84

'TAB3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.39 (Fisher's exact test), Q value = 0.77

Table S1358. Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
TAB3 MUTATED	9	2	5	2
TAB3 WILD-TYPE	64	41	74	43

'TAB3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0718 (Fisher's exact test), Q value = 0.42

Table S1359. Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
TAB3 MUTATED	0	3	3
TAB3 WILD-TYPE	29	16	61

'TAB3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.492 (Fisher's exact test), Q value = 0.85

Table S1360. Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
TAB3 MUTATED	1	2	3
TAB3 WILD-TYPE	32	46	28

'ZNF649 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.535 (Fisher's exact test), Q value = 0.88

Table S1361. Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ZNF649 MUTATED	2	2	0	0
ZNF649 WILD-TYPE	10	16	11	10

'ZNF649 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.245 (Fisher's exact test), Q value = 0.66

Table S1362. Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ZNF649 MUTATED	2	0	1	1	0
ZNF649 WILD-TYPE	10	10	6	6	15

'ZNF649 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0887 (Fisher's exact test), Q value = 0.46

Table S1363. Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF649 MUTATED	0	14	0	0	0
ZNF649 WILD-TYPE	56	138	11	5	18

'ZNF649 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1364. Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF649 MUTATED	2	2	3
ZNF649 WILD-TYPE	41	37	50

'ZNF649 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.693 (Fisher's exact test), Q value = 0.97

Table S1365. Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF649 MUTATED	6	5	3
ZNF649 WILD-TYPE	65	67	57

'ZNF649 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.956 (Fisher's exact test), Q value = 1

Table S1366. Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF649 MUTATED	4	6	2	2
ZNF649 WILD-TYPE	64	72	29	24

'ZNF649 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.942 (Fisher's exact test), Q value = 1

Table S1367. Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF649 MUTATED	5	5	4
ZNF649 WILD-TYPE	74	80	79

'ZNF649 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.014 (Fisher's exact test), Q value = 0.18

Table S1368. Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF649 MUTATED	1	0	1	6	3	0	3
ZNF649 WILD-TYPE	43	41	16	27	32	31	43

Figure S259. Get High-res Image Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF649 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 0.54

Table S1369. Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF649 MUTATED	1	7	5
ZNF649 WILD-TYPE	68	72	87

'ZNF649 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S1370. Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF649 MUTATED	5	1	4	3
ZNF649 WILD-TYPE	68	42	75	42

'ZNF649 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 0.77

Table S1371. Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZNF649 MUTATED	1	2	2
ZNF649 WILD-TYPE	28	17	62

'ZNF649 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.6 (Fisher's exact test), Q value = 0.92

Table S1372. Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZNF649 MUTATED	2	1	2
ZNF649 WILD-TYPE	31	47	29

'FN1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.183 (Fisher's exact test), Q value = 0.59

Table S1373. Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
FN1 MUTATED	3	3	0	0
FN1 WILD-TYPE	9	15	11	10

'FN1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0604 (Fisher's exact test), Q value = 0.38

Table S1374. Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
FN1 MUTATED	3	0	1	2	0
FN1 WILD-TYPE	9	10	6	5	15

'FN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0156 (Fisher's exact test), Q value = 0.19

Table S1375. Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
FN1 MUTATED	0	21	1	0	2
FN1 WILD-TYPE	56	131	10	5	16

Figure S260. Get High-res Image Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'FN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.411 (Fisher's exact test), Q value = 0.79

Table S1376. Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
FN1 MUTATED	3	2	7
FN1 WILD-TYPE	40	37	46

'FN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.355 (Fisher's exact test), Q value = 0.77

Table S1377. Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
FN1 MUTATED	7	9	3
FN1 WILD-TYPE	64	63	57

'FN1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.522 (Fisher's exact test), Q value = 0.87

Table S1378. Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
FN1 MUTATED	4	10	3	2
FN1 WILD-TYPE	64	68	28	24

'FN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 0.52

Table S1379. Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
FN1 MUTATED	8	12	4
FN1 WILD-TYPE	71	73	79

'FN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S1380. Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
FN1 MUTATED	1	0	2	10	8	1	2
FN1 WILD-TYPE	43	41	15	23	27	30	44

Figure S261. Get High-res Image Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.268 (Fisher's exact test), Q value = 0.69

Table S1381. Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
FN1 MUTATED	4	11	8
FN1 WILD-TYPE	65	68	84

'FN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0129 (Fisher's exact test), Q value = 0.17

Table S1382. Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
FN1 MUTATED	14	1	5	3
FN1 WILD-TYPE	59	42	74	42

Figure S262. Get High-res Image Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'FN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.556 (Fisher's exact test), Q value = 0.89

Table S1383. Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
FN1 MUTATED	2	3	6
FN1 WILD-TYPE	27	16	58

'FN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0841 (Fisher's exact test), Q value = 0.44

Table S1384. Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
FN1 MUTATED	3	2	6
FN1 WILD-TYPE	30	46	25

'CCDC150 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.27 (Fisher's exact test), Q value = 0.7

Table S1385. Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CCDC150 MUTATED	0	10	0	0	0
CCDC150 WILD-TYPE	56	142	11	5	18

'CCDC150 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.387 (Fisher's exact test), Q value = 0.77

Table S1386. Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CCDC150 MUTATED	2	1	5
CCDC150 WILD-TYPE	41	38	48

'CCDC150 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.432 (Fisher's exact test), Q value = 0.79

Table S1387. Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CCDC150 MUTATED	6	3	2
CCDC150 WILD-TYPE	65	69	58

'CCDC150 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.054 (Fisher's exact test), Q value = 0.36

Table S1388. Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CCDC150 MUTATED	3	2	5	1
CCDC150 WILD-TYPE	65	76	26	25

'CCDC150 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.863 (Fisher's exact test), Q value = 1

Table S1389. Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CCDC150 MUTATED	4	3	4
CCDC150 WILD-TYPE	75	82	79

'CCDC150 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.064 (Fisher's exact test), Q value = 0.39

Table S1390. Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CCDC150 MUTATED	0	0	1	4	3	1	2
CCDC150 WILD-TYPE	44	41	16	29	32	30	44

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.783 (Fisher's exact test), Q value = 1

Table S1391. Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CCDC150 MUTATED	2	3	5
CCDC150 WILD-TYPE	67	76	87

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.538 (Fisher's exact test), Q value = 0.88

Table S1392. Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CCDC150 MUTATED	4	0	4	2
CCDC150 WILD-TYPE	69	43	75	43

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1393. Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CCDC150 MUTATED	1	1	4
CCDC150 WILD-TYPE	28	18	60

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.493 (Fisher's exact test), Q value = 0.85

Table S1394. Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CCDC150 MUTATED	1	2	3
CCDC150 WILD-TYPE	32	46	28

'KIF21A MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.685 (Fisher's exact test), Q value = 0.97

Table S1395. Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
KIF21A MUTATED	1	2	0	0
KIF21A WILD-TYPE	11	16	11	10

'KIF21A MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.206 (Fisher's exact test), Q value = 0.6

Table S1396. Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
KIF21A MUTATED	2	0	1	0	0
KIF21A WILD-TYPE	10	10	6	7	15

'KIF21A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0887 (Fisher's exact test), Q value = 0.46

Table S1397. Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
KIF21A MUTATED	0	13	0	0	2
KIF21A WILD-TYPE	56	139	11	5	16

'KIF21A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0526 (Fisher's exact test), Q value = 0.35

Table S1398. Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
KIF21A MUTATED	0	2	6
KIF21A WILD-TYPE	43	37	47

'KIF21A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S1399. Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
KIF21A MUTATED	5	4	5
KIF21A WILD-TYPE	66	68	55

'KIF21A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.586 (Fisher's exact test), Q value = 0.91

Table S1400. Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
KIF21A MUTATED	4	5	4	1
KIF21A WILD-TYPE	64	73	27	25

'KIF21A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 0.79

Table S1401. Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
KIF21A MUTATED	5	7	3
KIF21A WILD-TYPE	74	78	80

'KIF21A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00097 (Fisher's exact test), Q value = 0.028

Table S1402. Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
KIF21A MUTATED	1	0	0	5	7	1	1
KIF21A WILD-TYPE	43	41	17	28	28	30	45

Figure S263. Get High-res Image Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'KIF21A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.452 (Fisher's exact test), Q value = 0.81

Table S1403. Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
KIF21A MUTATED	2	5	7
KIF21A WILD-TYPE	67	74	85

'KIF21A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0693 (Fisher's exact test), Q value = 0.41

Table S1404. Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
KIF21A MUTATED	9	1	3	1
KIF21A WILD-TYPE	64	42	76	44

'KIF21A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1405. Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
KIF21A MUTATED	1	0	3
KIF21A WILD-TYPE	28	19	61

'KIF21A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.687 (Fisher's exact test), Q value = 0.97

Table S1406. Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
KIF21A MUTATED	1	1	2
KIF21A WILD-TYPE	32	47	29

'BHLHB9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 0.77

Table S1407. Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
BHLHB9 MUTATED	0	7	0	0	1
BHLHB9 WILD-TYPE	56	145	11	5	17

'BHLHB9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1408. Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
BHLHB9 MUTATED	1	1	2
BHLHB9 WILD-TYPE	42	38	51

'BHLHB9 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S1409. Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
BHLHB9 MUTATED	2	2	3
BHLHB9 WILD-TYPE	69	70	57

'BHLHB9 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.247 (Fisher's exact test), Q value = 0.67

Table S1410. Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
BHLHB9 MUTATED	1	2	2	2
BHLHB9 WILD-TYPE	67	76	29	24

'BHLHB9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.122 (Fisher's exact test), Q value = 0.52

Table S1411. Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
BHLHB9 MUTATED	4	4	0
BHLHB9 WILD-TYPE	75	81	83

'BHLHB9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0359 (Fisher's exact test), Q value = 0.3

Table S1412. Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
BHLHB9 MUTATED	1	0	1	3	3	0	0
BHLHB9 WILD-TYPE	43	41	16	30	32	31	46

Figure S264. Get High-res Image Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'BHLHB9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.28 (Fisher's exact test), Q value = 0.7

Table S1413. Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
BHLHB9 MUTATED	3	4	1
BHLHB9 WILD-TYPE	66	75	91

'BHLHB9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.156 (Fisher's exact test), Q value = 0.57

Table S1414. Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
BHLHB9 MUTATED	5	0	1	2
BHLHB9 WILD-TYPE	68	43	78	43

'EXOSC9 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 0.97

Table S1415. Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
EXOSC9 MUTATED	1	2	0	0
EXOSC9 WILD-TYPE	11	16	11	10

'EXOSC9 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.203 (Fisher's exact test), Q value = 0.6

Table S1416. Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
EXOSC9 MUTATED	2	0	1	0	0
EXOSC9 WILD-TYPE	10	10	6	7	15

'EXOSC9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 0.77

Table S1417. Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
EXOSC9 MUTATED	0	9	0	0	1
EXOSC9 WILD-TYPE	56	143	11	5	17

'EXOSC9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 0.51

Table S1418. Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
EXOSC9 MUTATED	0	0	3
EXOSC9 WILD-TYPE	43	39	50

'EXOSC9 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1419. Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
EXOSC9 MUTATED	3	3	2
EXOSC9 WILD-TYPE	68	69	58

'EXOSC9 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.746 (Fisher's exact test), Q value = 1

Table S1420. Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
EXOSC9 MUTATED	3	2	2	1
EXOSC9 WILD-TYPE	65	76	29	25

'EXOSC9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 0.87

Table S1421. Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
EXOSC9 MUTATED	3	5	2
EXOSC9 WILD-TYPE	76	80	81

'EXOSC9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00119 (Fisher's exact test), Q value = 0.032

Table S1422. Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
EXOSC9 MUTATED	0	0	0	4	5	0	1
EXOSC9 WILD-TYPE	44	41	17	29	30	31	45

Figure S265. Get High-res Image Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'EXOSC9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.763 (Fisher's exact test), Q value = 1

Table S1423. Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
EXOSC9 MUTATED	2	4	3
EXOSC9 WILD-TYPE	67	75	89

'EXOSC9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.725 (Fisher's exact test), Q value = 0.99

Table S1424. Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
EXOSC9 MUTATED	2	1	3	3
EXOSC9 WILD-TYPE	71	42	76	42

'ZKSCAN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.498 (Fisher's exact test), Q value = 0.85

Table S1425. Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZKSCAN1 MUTATED	0	7	0	0	0
ZKSCAN1 WILD-TYPE	56	145	11	5	18

'ZKSCAN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.445 (Fisher's exact test), Q value = 0.81

Table S1426. Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZKSCAN1 MUTATED	2	0	3
ZKSCAN1 WILD-TYPE	41	39	50

'ZKSCAN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 0.5

Table S1427. Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZKSCAN1 MUTATED	5	2	0
ZKSCAN1 WILD-TYPE	66	70	60

'ZKSCAN1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.162 (Fisher's exact test), Q value = 0.58

Table S1428. Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZKSCAN1 MUTATED	2	1	3	1
ZKSCAN1 WILD-TYPE	66	77	28	25

'ZKSCAN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.405 (Fisher's exact test), Q value = 0.78

Table S1429. Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZKSCAN1 MUTATED	2	4	1
ZKSCAN1 WILD-TYPE	77	81	82

'ZKSCAN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0235 (Fisher's exact test), Q value = 0.23

Table S1430. Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZKSCAN1 MUTATED	0	0	2	3	1	0	1
ZKSCAN1 WILD-TYPE	44	41	15	30	34	31	45

Figure S266. Get High-res Image Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZKSCAN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.715 (Fisher's exact test), Q value = 0.98

Table S1431. Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZKSCAN1 MUTATED	3	2	2
ZKSCAN1 WILD-TYPE	66	77	90

'ZKSCAN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.277 (Fisher's exact test), Q value = 0.7

Table S1432. Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZKSCAN1 MUTATED	4	0	1	2
ZKSCAN1 WILD-TYPE	69	43	78	43

'ZKSCAN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.805 (Fisher's exact test), Q value = 1

Table S1433. Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZKSCAN1 MUTATED	1	1	2
ZKSCAN1 WILD-TYPE	28	18	62

'ZKSCAN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S1434. Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZKSCAN1 MUTATED	2	1	1
ZKSCAN1 WILD-TYPE	31	47	30

'OR8B8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.189 (Fisher's exact test), Q value = 0.59

Table S1435. Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
OR8B8 MUTATED	0	5	0	0	2
OR8B8 WILD-TYPE	56	147	11	5	16

'OR8B8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S1436. Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
OR8B8 MUTATED	1	0	2
OR8B8 WILD-TYPE	42	39	51

'OR8B8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.247 (Fisher's exact test), Q value = 0.67

Table S1437. Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
OR8B8 MUTATED	2	4	0
OR8B8 WILD-TYPE	69	68	60

'OR8B8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.425 (Fisher's exact test), Q value = 0.79

Table S1438. Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
OR8B8 MUTATED	1	3	2	0
OR8B8 WILD-TYPE	67	75	29	26

'OR8B8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.308 (Fisher's exact test), Q value = 0.72

Table S1439. Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
OR8B8 MUTATED	4	2	1
OR8B8 WILD-TYPE	75	83	82

'OR8B8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00537 (Fisher's exact test), Q value = 0.09

Table S1440. Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
OR8B8 MUTATED	0	0	2	2	3	0	0
OR8B8 WILD-TYPE	44	41	15	31	32	31	46

Figure S267. Get High-res Image Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'OR8B8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.386 (Fisher's exact test), Q value = 0.77

Table S1441. Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
OR8B8 MUTATED	3	3	1
OR8B8 WILD-TYPE	66	76	91

'OR8B8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.427 (Fisher's exact test), Q value = 0.79

Table S1442. Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
OR8B8 MUTATED	4	1	2	0
OR8B8 WILD-TYPE	69	42	77	45

'SENP7 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.376 (Fisher's exact test), Q value = 0.77

Table S1443. Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
SENP7 MUTATED	2	3	0	0
SENP7 WILD-TYPE	10	15	11	10

'SENP7 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0355 (Fisher's exact test), Q value = 0.3

Table S1444. Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
SENP7 MUTATED	3	0	0	2	0
SENP7 WILD-TYPE	9	10	7	5	15

Figure S268. Get High-res Image Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'SENP7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.147 (Fisher's exact test), Q value = 0.55

Table S1445. Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SENP7 MUTATED	0	10	0	0	2
SENP7 WILD-TYPE	56	142	11	5	16

'SENP7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 0.8

Table S1446. Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SENP7 MUTATED	2	0	3
SENP7 WILD-TYPE	41	39	50

'SENP7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.926 (Fisher's exact test), Q value = 1

Table S1447. Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SENP7 MUTATED	3	4	4
SENP7 WILD-TYPE	68	68	56

'SENP7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.664 (Fisher's exact test), Q value = 0.97

Table S1448. Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SENP7 MUTATED	2	6	2	1
SENP7 WILD-TYPE	66	72	29	25

'SENP7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0151 (Fisher's exact test), Q value = 0.19

Table S1449. Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SENP7 MUTATED	7	5	0
SENP7 WILD-TYPE	72	80	83

Figure S269. Get High-res Image Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'SENP7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 6e-05 (Fisher's exact test), Q value = 0.0035

Table S1450. Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SENP7 MUTATED	0	0	1	5	6	0	0
SENP7 WILD-TYPE	44	41	16	28	29	31	46

Figure S270. Get High-res Image Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SENP7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.121 (Fisher's exact test), Q value = 0.52

Table S1451. Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SENP7 MUTATED	2	7	2
SENP7 WILD-TYPE	67	72	90

'SENP7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0123 (Fisher's exact test), Q value = 0.17

Table S1452. Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SENP7 MUTATED	8	0	1	2
SENP7 WILD-TYPE	65	43	78	43

Figure S271. Get High-res Image Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'WDR65 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.427 (Fisher's exact test), Q value = 0.79

Table S1453. Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
WDR65 MUTATED	0	5	0	0	1
WDR65 WILD-TYPE	56	147	11	5	17

'WDR65 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.732 (Fisher's exact test), Q value = 0.99

Table S1454. Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
WDR65 MUTATED	1	1	3
WDR65 WILD-TYPE	42	38	50

'WDR65 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S1455. Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
WDR65 MUTATED	2	3	1
WDR65 WILD-TYPE	69	69	59

'WDR65 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.609 (Fisher's exact test), Q value = 0.93

Table S1456. Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
WDR65 MUTATED	2	2	2	0
WDR65 WILD-TYPE	66	76	29	26

'WDR65 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.45 (Fisher's exact test), Q value = 0.81

Table S1457. Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
WDR65 MUTATED	3	1	2
WDR65 WILD-TYPE	76	84	81

'WDR65 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0892 (Fisher's exact test), Q value = 0.46

Table S1458. Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
WDR65 MUTATED	0	0	0	2	3	0	1
WDR65 WILD-TYPE	44	41	17	31	32	31	45

'WDR65 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.162 (Fisher's exact test), Q value = 0.58

Table S1459. Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
WDR65 MUTATED	0	4	2
WDR65 WILD-TYPE	69	75	90

'WDR65 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.673 (Fisher's exact test), Q value = 0.97

Table S1460. Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
WDR65 MUTATED	3	0	2	1
WDR65 WILD-TYPE	70	43	77	44

'WDR65 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.562 (Fisher's exact test), Q value = 0.89

Table S1461. Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
WDR65 MUTATED	0	1	2
WDR65 WILD-TYPE	29	18	62

'WDR65 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.357 (Fisher's exact test), Q value = 0.77

Table S1462. Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
WDR65 MUTATED	0	1	2
WDR65 WILD-TYPE	33	47	29

'NRIP1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.383 (Fisher's exact test), Q value = 0.77

Table S1463. Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
NRIP1 MUTATED	2	1	0	0
NRIP1 WILD-TYPE	10	17	11	10

'NRIP1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0785 (Fisher's exact test), Q value = 0.43

Table S1464. Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
NRIP1 MUTATED	1	0	0	2	0
NRIP1 WILD-TYPE	11	10	7	5	15

'NRIP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.45 (Fisher's exact test), Q value = 0.81

Table S1465. Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
NRIP1 MUTATED	1	10	0	0	2
NRIP1 WILD-TYPE	55	142	11	5	16

'NRIP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.717 (Fisher's exact test), Q value = 0.98

Table S1466. Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
NRIP1 MUTATED	3	1	3
NRIP1 WILD-TYPE	40	38	50

'NRIP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.934 (Fisher's exact test), Q value = 1

Table S1467. Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
NRIP1 MUTATED	4	5	3
NRIP1 WILD-TYPE	67	67	57

'NRIP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.222 (Fisher's exact test), Q value = 0.63

Table S1468. Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
NRIP1 MUTATED	3	5	4	0
NRIP1 WILD-TYPE	65	73	27	26

'NRIP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 0.74

Table S1469. Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
NRIP1 MUTATED	6	5	2
NRIP1 WILD-TYPE	73	80	81

'NRIP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00059 (Fisher's exact test), Q value = 0.019

Table S1470. Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
NRIP1 MUTATED	0	0	2	5	5	0	1
NRIP1 WILD-TYPE	44	41	15	28	30	31	45

Figure S272. Get High-res Image Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NRIP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 0.55

Table S1471. Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
NRIP1 MUTATED	4	7	2
NRIP1 WILD-TYPE	65	72	90

'NRIP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.133 (Fisher's exact test), Q value = 0.53

Table S1472. Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
NRIP1 MUTATED	7	0	3	3
NRIP1 WILD-TYPE	66	43	76	42

'NRIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.358 (Fisher's exact test), Q value = 0.77

Table S1473. Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
NRIP1 MUTATED	1	2	2
NRIP1 WILD-TYPE	28	17	62

'NRIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.599 (Fisher's exact test), Q value = 0.92

Table S1474. Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
NRIP1 MUTATED	2	1	2
NRIP1 WILD-TYPE	31	47	29

'MCTP1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.383 (Fisher's exact test), Q value = 0.77

Table S1475. Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
MCTP1 MUTATED	2	1	0	0
MCTP1 WILD-TYPE	10	17	11	10

'MCTP1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.229 (Fisher's exact test), Q value = 0.64

Table S1476. Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
MCTP1 MUTATED	0	1	1	1	0
MCTP1 WILD-TYPE	12	9	6	6	15

'MCTP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.566 (Fisher's exact test), Q value = 0.89

Table S1477. Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MCTP1 MUTATED	1	11	0	0	1
MCTP1 WILD-TYPE	55	141	11	5	17

'MCTP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.669 (Fisher's exact test), Q value = 0.97

Table S1478. Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MCTP1 MUTATED	3	1	2
MCTP1 WILD-TYPE	40	38	51

'MCTP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S1479. Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MCTP1 MUTATED	3	5	3
MCTP1 WILD-TYPE	68	67	57

'MCTP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.731 (Fisher's exact test), Q value = 0.99

Table S1480. Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MCTP1 MUTATED	4	5	2	0
MCTP1 WILD-TYPE	64	73	29	26

'MCTP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 0.87

Table S1481. Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MCTP1 MUTATED	6	4	3
MCTP1 WILD-TYPE	73	81	80

'MCTP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0214 (Fisher's exact test), Q value = 0.23

Table S1482. Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MCTP1 MUTATED	1	0	1	5	4	0	2
MCTP1 WILD-TYPE	43	41	16	28	31	31	44

Figure S273. Get High-res Image Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MCTP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.189 (Fisher's exact test), Q value = 0.59

Table S1483. Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MCTP1 MUTATED	2	7	3
MCTP1 WILD-TYPE	67	72	89

'MCTP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S1484. Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MCTP1 MUTATED	5	2	4	1
MCTP1 WILD-TYPE	68	41	75	44

'MCTP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0193 (Fisher's exact test), Q value = 0.21

Table S1485. Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MCTP1 MUTATED	0	3	1
MCTP1 WILD-TYPE	29	16	63

Figure S274. Get High-res Image Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'MCTP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0356 (Fisher's exact test), Q value = 0.3

Table S1486. Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MCTP1 MUTATED	1	0	3
MCTP1 WILD-TYPE	32	48	28

Figure S275. Get High-res Image Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CCDC146 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S1487. Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
CCDC146 MUTATED	1	2	1	0
CCDC146 WILD-TYPE	11	16	10	10

'CCDC146 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0479 (Fisher's exact test), Q value = 0.33

Table S1488. Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
CCDC146 MUTATED	2	0	2	0	0
CCDC146 WILD-TYPE	10	10	5	7	15

Figure S276. Get High-res Image Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'CCDC146 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.12 (Fisher's exact test), Q value = 0.52

Table S1489. Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CCDC146 MUTATED	0	12	0	0	2
CCDC146 WILD-TYPE	56	140	11	5	16

'CCDC146 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.634 (Fisher's exact test), Q value = 0.95

Table S1490. Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CCDC146 MUTATED	2	1	4
CCDC146 WILD-TYPE	41	38	49

'CCDC146 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 0.85

Table S1491. Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CCDC146 MUTATED	4	6	2
CCDC146 WILD-TYPE	67	66	58

'CCDC146 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.362 (Fisher's exact test), Q value = 0.77

Table S1492. Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CCDC146 MUTATED	3	6	3	0
CCDC146 WILD-TYPE	65	72	28	26

'CCDC146 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 0.89

Table S1493. Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CCDC146 MUTATED	6	5	3
CCDC146 WILD-TYPE	73	80	80

'CCDC146 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00082 (Fisher's exact test), Q value = 0.025

Table S1494. Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CCDC146 MUTATED	0	0	1	5	6	1	1
CCDC146 WILD-TYPE	44	41	16	28	29	30	45

Figure S277. Get High-res Image Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CCDC146 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 0.71

Table S1495. Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CCDC146 MUTATED	3	7	3
CCDC146 WILD-TYPE	66	72	89

'CCDC146 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.375 (Fisher's exact test), Q value = 0.77

Table S1496. Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CCDC146 MUTATED	7	1	3	2
CCDC146 WILD-TYPE	66	42	76	43

'CCDC146 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.175 (Fisher's exact test), Q value = 0.58

Table S1497. Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CCDC146 MUTATED	0	2	3
CCDC146 WILD-TYPE	29	17	61

'CCDC146 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.326 (Fisher's exact test), Q value = 0.74

Table S1498. Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CCDC146 MUTATED	1	1	3
CCDC146 WILD-TYPE	32	47	28

'ZNF620 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.753 (Fisher's exact test), Q value = 1

Table S1499. Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF620 MUTATED	1	7	0	0	1
ZNF620 WILD-TYPE	55	145	11	5	17

'ZNF620 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1500. Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF620 MUTATED	2	1	2
ZNF620 WILD-TYPE	41	38	51

'ZNF620 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 0.77

Table S1501. Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF620 MUTATED	3	5	1
ZNF620 WILD-TYPE	68	67	59

'ZNF620 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.422 (Fisher's exact test), Q value = 0.79

Table S1502. Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF620 MUTATED	1	5	2	1
ZNF620 WILD-TYPE	67	73	29	25

'ZNF620 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 0.77

Table S1503. Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF620 MUTATED	5	2	2
ZNF620 WILD-TYPE	74	83	81

'ZNF620 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0625 (Fisher's exact test), Q value = 0.39

Table S1504. Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF620 MUTATED	1	0	1	2	4	1	0
ZNF620 WILD-TYPE	43	41	16	31	31	30	46

'ZNF620 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.601 (Fisher's exact test), Q value = 0.92

Table S1505. Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF620 MUTATED	2	4	2
ZNF620 WILD-TYPE	67	75	90

'ZNF620 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0578 (Fisher's exact test), Q value = 0.37

Table S1506. Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF620 MUTATED	6	0	1	1
ZNF620 WILD-TYPE	67	43	78	44

'ZNF620 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 0.53

Table S1507. Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZNF620 MUTATED	1	2	1
ZNF620 WILD-TYPE	28	17	63

'ZNF620 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.169 (Fisher's exact test), Q value = 0.58

Table S1508. Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZNF620 MUTATED	2	0	2
ZNF620 WILD-TYPE	31	48	29

'PTPN12 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0558 (Fisher's exact test), Q value = 0.36

Table S1509. Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
PTPN12 MUTATED	3	0	1	0
PTPN12 WILD-TYPE	9	18	10	10

'PTPN12 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.151 (Fisher's exact test), Q value = 0.56

Table S1510. Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
PTPN12 MUTATED	0	0	2	1	1
PTPN12 WILD-TYPE	12	10	5	6	14

'PTPN12 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.166 (Fisher's exact test), Q value = 0.58

Table S1511. Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PTPN12 MUTATED	0	8	0	0	2
PTPN12 WILD-TYPE	56	144	11	5	16

'PTPN12 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S1512. Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PTPN12 MUTATED	1	0	2
PTPN12 WILD-TYPE	42	39	51

'PTPN12 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0682 (Fisher's exact test), Q value = 0.4

Table S1513. Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PTPN12 MUTATED	5	5	0
PTPN12 WILD-TYPE	66	67	60

'PTPN12 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.899 (Fisher's exact test), Q value = 1

Table S1514. Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PTPN12 MUTATED	4	3	2	1
PTPN12 WILD-TYPE	64	75	29	25

'PTPN12 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 0.72

Table S1515. Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PTPN12 MUTATED	2	6	2
PTPN12 WILD-TYPE	77	79	81

'PTPN12 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0134 (Fisher's exact test), Q value = 0.18

Table S1516. Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PTPN12 MUTATED	0	0	1	2	5	0	2
PTPN12 WILD-TYPE	44	41	16	31	30	31	44

Figure S278. Get High-res Image Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PTPN12 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1517. Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PTPN12 MUTATED	3	3	4
PTPN12 WILD-TYPE	66	76	88

'PTPN12 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.621 (Fisher's exact test), Q value = 0.94

Table S1518. Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PTPN12 MUTATED	5	1	3	1
PTPN12 WILD-TYPE	68	42	76	44

'RIOK3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.194 (Fisher's exact test), Q value = 0.59

Table S1519. Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
RIOK3 MUTATED	0	7	0	0	2
RIOK3 WILD-TYPE	56	145	11	5	16

'RIOK3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.51 (Fisher's exact test), Q value = 0.86

Table S1520. Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
RIOK3 MUTATED	1	1	4
RIOK3 WILD-TYPE	42	38	49

'RIOK3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1521. Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
RIOK3 MUTATED	3	3	2
RIOK3 WILD-TYPE	68	69	58

'RIOK3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S1522. Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
RIOK3 MUTATED	3	4	1	0
RIOK3 WILD-TYPE	65	74	30	26

'RIOK3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 0.78

Table S1523. Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
RIOK3 MUTATED	5	2	2
RIOK3 WILD-TYPE	74	83	81

'RIOK3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0154 (Fisher's exact test), Q value = 0.19

Table S1524. Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
RIOK3 MUTATED	0	0	1	3	4	0	1
RIOK3 WILD-TYPE	44	41	16	30	31	31	45

Figure S279. Get High-res Image Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RIOK3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1525. Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
RIOK3 MUTATED	2	3	3
RIOK3 WILD-TYPE	67	76	89

'RIOK3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.696 (Fisher's exact test), Q value = 0.98

Table S1526. Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
RIOK3 MUTATED	3	0	3	2
RIOK3 WILD-TYPE	70	43	76	43

'RIOK3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.495 (Fisher's exact test), Q value = 0.85

Table S1527. Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
RIOK3 MUTATED	0	1	3
RIOK3 WILD-TYPE	29	18	61

'RIOK3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.689 (Fisher's exact test), Q value = 0.97

Table S1528. Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
RIOK3 MUTATED	1	1	2
RIOK3 WILD-TYPE	32	47	29

'CASP8 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 0.77

Table S1529. Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
CASP8 MUTATED	2	1	0	0
CASP8 WILD-TYPE	10	17	11	10

'CASP8 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0781 (Fisher's exact test), Q value = 0.43

Table S1530. Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
CASP8 MUTATED	1	0	2	0	0
CASP8 WILD-TYPE	11	10	5	7	15

'CASP8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.262 (Fisher's exact test), Q value = 0.69

Table S1531. Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CASP8 MUTATED	1	14	0	0	2
CASP8 WILD-TYPE	55	138	11	5	16

'CASP8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 0.67

Table S1532. Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CASP8 MUTATED	2	1	6
CASP8 WILD-TYPE	41	38	47

'CASP8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.9 (Fisher's exact test), Q value = 1

Table S1533. Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CASP8 MUTATED	6	6	4
CASP8 WILD-TYPE	65	66	56

'CASP8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 0.97

Table S1534. Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CASP8 MUTATED	4	8	3	1
CASP8 WILD-TYPE	64	70	28	25

'CASP8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.601 (Fisher's exact test), Q value = 0.92

Table S1535. Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CASP8 MUTATED	7	6	4
CASP8 WILD-TYPE	72	79	79

'CASP8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00395 (Fisher's exact test), Q value = 0.075

Table S1536. Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CASP8 MUTATED	0	1	3	3	7	1	2
CASP8 WILD-TYPE	44	40	14	30	28	30	44

Figure S280. Get High-res Image Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CASP8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 0.73

Table S1537. Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CASP8 MUTATED	7	3	6
CASP8 WILD-TYPE	62	76	86

'CASP8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.745 (Fisher's exact test), Q value = 1

Table S1538. Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CASP8 MUTATED	7	2	5	2
CASP8 WILD-TYPE	66	41	74	43

'CASP8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1539. Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CASP8 MUTATED	2	1	4
CASP8 WILD-TYPE	27	18	60

'CASP8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.633 (Fisher's exact test), Q value = 0.95

Table S1540. Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CASP8 MUTATED	3	2	2
CASP8 WILD-TYPE	30	46	29

'GFAP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 0.79

Table S1541. Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
GFAP MUTATED	0	5	0	0	1
GFAP WILD-TYPE	56	147	11	5	17

'GFAP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.557 (Fisher's exact test), Q value = 0.89

Table S1542. Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
GFAP MUTATED	2	0	2
GFAP WILD-TYPE	41	39	51

'GFAP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0519 (Fisher's exact test), Q value = 0.35

Table S1543. Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
GFAP MUTATED	1	5	0
GFAP WILD-TYPE	70	67	60

'GFAP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.196 (Fisher's exact test), Q value = 0.59

Table S1544. Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
GFAP MUTATED	0	4	1	1
GFAP WILD-TYPE	68	74	30	25

'GFAP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.22 (Fisher's exact test), Q value = 0.63

Table S1545. Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
GFAP MUTATED	3	3	0
GFAP WILD-TYPE	76	82	83

'GFAP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0156 (Fisher's exact test), Q value = 0.19

Table S1546. Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
GFAP MUTATED	0	0	1	3	2	0	0
GFAP WILD-TYPE	44	41	16	30	33	31	46

Figure S281. Get High-res Image Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'GFAP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 0.7

Table S1547. Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
GFAP MUTATED	1	4	1
GFAP WILD-TYPE	68	75	91

'GFAP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0216 (Fisher's exact test), Q value = 0.23

Table S1548. Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
GFAP MUTATED	5	1	0	0
GFAP WILD-TYPE	68	42	79	45

Figure S282. Get High-res Image Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'OMA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.194 (Fisher's exact test), Q value = 0.59

Table S1549. Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
OMA1 MUTATED	0	7	0	0	2
OMA1 WILD-TYPE	56	145	11	5	16

'OMA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 0.86

Table S1550. Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
OMA1 MUTATED	1	1	4
OMA1 WILD-TYPE	42	38	49

'OMA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0982 (Fisher's exact test), Q value = 0.47

Table S1551. Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
OMA1 MUTATED	4	5	0
OMA1 WILD-TYPE	67	67	60

'OMA1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1552. Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
OMA1 MUTATED	3	4	1	1
OMA1 WILD-TYPE	65	74	30	25

'OMA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1553. Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
OMA1 MUTATED	3	4	3
OMA1 WILD-TYPE	76	81	80

'OMA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0532 (Fisher's exact test), Q value = 0.35

Table S1554. Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
OMA1 MUTATED	0	0	0	4	3	1	2
OMA1 WILD-TYPE	44	41	17	29	32	30	44

'OMA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.435 (Fisher's exact test), Q value = 0.8

Table S1555. Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
OMA1 MUTATED	1	4	5
OMA1 WILD-TYPE	68	75	87

'OMA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.283 (Fisher's exact test), Q value = 0.7

Table S1556. Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
OMA1 MUTATED	5	1	4	0
OMA1 WILD-TYPE	68	42	75	45

'OMA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.497 (Fisher's exact test), Q value = 0.85

Table S1557. Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
OMA1 MUTATED	0	1	3
OMA1 WILD-TYPE	29	18	61

'OMA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.297 (Fisher's exact test), Q value = 0.71

Table S1558. Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
OMA1 MUTATED	0	2	2
OMA1 WILD-TYPE	33	46	29

'DENND3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.379 (Fisher's exact test), Q value = 0.77

Table S1559. Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
DENND3 MUTATED	2	1	0	0
DENND3 WILD-TYPE	10	17	11	10

'DENND3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.28 (Fisher's exact test), Q value = 0.7

Table S1560. Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
DENND3 MUTATED	1	0	1	1	0
DENND3 WILD-TYPE	11	10	6	6	15

'DENND3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0894 (Fisher's exact test), Q value = 0.46

Table S1561. Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
DENND3 MUTATED	0	13	0	0	2
DENND3 WILD-TYPE	56	139	11	5	16

'DENND3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.6

Table S1562. Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
DENND3 MUTATED	3	0	4
DENND3 WILD-TYPE	40	39	49

'DENND3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.516 (Fisher's exact test), Q value = 0.87

Table S1563. Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
DENND3 MUTATED	5	6	2
DENND3 WILD-TYPE	66	66	58

'DENND3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.238 (Fisher's exact test), Q value = 0.65

Table S1564. Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
DENND3 MUTATED	2	6	4	1
DENND3 WILD-TYPE	66	72	27	25

'DENND3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0481 (Fisher's exact test), Q value = 0.33

Table S1565. Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
DENND3 MUTATED	6	8	1
DENND3 WILD-TYPE	73	77	82

Figure S283. Get High-res Image Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'DENND3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00082

Table S1566. Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
DENND3 MUTATED	0	0	3	6	6	0	0
DENND3 WILD-TYPE	44	41	14	27	29	31	46

Figure S284. Get High-res Image Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'DENND3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.276 (Fisher's exact test), Q value = 0.7

Table S1567. Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
DENND3 MUTATED	5	7	3
DENND3 WILD-TYPE	64	72	89

'DENND3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.244 (Fisher's exact test), Q value = 0.66

Table S1568. Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
DENND3 MUTATED	8	1	3	3
DENND3 WILD-TYPE	65	42	76	42

'DENND3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 0.53

Table S1569. Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
DENND3 MUTATED	1	2	1
DENND3 WILD-TYPE	28	17	63

'DENND3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.168 (Fisher's exact test), Q value = 0.58

Table S1570. Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
DENND3 MUTATED	2	0	2
DENND3 WILD-TYPE	31	48	29

'CHEK2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.685 (Fisher's exact test), Q value = 0.97

Table S1571. Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
CHEK2 MUTATED	1	2	0	0
CHEK2 WILD-TYPE	11	16	11	10

'CHEK2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.206 (Fisher's exact test), Q value = 0.6

Table S1572. Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
CHEK2 MUTATED	2	0	1	0	0
CHEK2 WILD-TYPE	10	10	6	7	15

'CHEK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.416 (Fisher's exact test), Q value = 0.79

Table S1573. Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CHEK2 MUTATED	1	9	0	0	2
CHEK2 WILD-TYPE	55	143	11	5	16

'CHEK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.282 (Fisher's exact test), Q value = 0.7

Table S1574. Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CHEK2 MUTATED	2	0	4
CHEK2 WILD-TYPE	41	39	49

'CHEK2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S1575. Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CHEK2 MUTATED	2	4	3
CHEK2 WILD-TYPE	69	68	57

'CHEK2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.141 (Fisher's exact test), Q value = 0.54

Table S1576. Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CHEK2 MUTATED	1	5	3	0
CHEK2 WILD-TYPE	67	73	28	26

'CHEK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.166 (Fisher's exact test), Q value = 0.58

Table S1577. Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CHEK2 MUTATED	7	3	2
CHEK2 WILD-TYPE	72	82	81

'CHEK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 5e-04 (Fisher's exact test), Q value = 0.017

Table S1578. Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CHEK2 MUTATED	1	0	0	3	7	1	0
CHEK2 WILD-TYPE	43	41	17	30	28	30	46

Figure S285. Get High-res Image Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CHEK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.392 (Fisher's exact test), Q value = 0.77

Table S1579. Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CHEK2 MUTATED	2	6	3
CHEK2 WILD-TYPE	67	73	89

'CHEK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.653 (Fisher's exact test), Q value = 0.96

Table S1580. Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CHEK2 MUTATED	5	1	4	1
CHEK2 WILD-TYPE	68	42	75	44

'CHEK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.806 (Fisher's exact test), Q value = 1

Table S1581. Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CHEK2 MUTATED	1	1	2
CHEK2 WILD-TYPE	28	18	62

'CHEK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.294 (Fisher's exact test), Q value = 0.7

Table S1582. Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CHEK2 MUTATED	0	2	2
CHEK2 WILD-TYPE	33	46	29

'ZMYM2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 0.77

Table S1583. Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ZMYM2 MUTATED	2	1	0	0
ZMYM2 WILD-TYPE	10	17	11	10

'ZMYM2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0782 (Fisher's exact test), Q value = 0.43

Table S1584. Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ZMYM2 MUTATED	1	0	0	2	0
ZMYM2 WILD-TYPE	11	10	7	5	15

'ZMYM2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 0.72

Table S1585. Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZMYM2 MUTATED	1	13	0	0	2
ZMYM2 WILD-TYPE	55	139	11	5	16

'ZMYM2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1586. Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZMYM2 MUTATED	3	2	4
ZMYM2 WILD-TYPE	40	37	49

'ZMYM2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S1587. Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZMYM2 MUTATED	5	5	3
ZMYM2 WILD-TYPE	66	67	57

'ZMYM2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.254 (Fisher's exact test), Q value = 0.67

Table S1588. Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZMYM2 MUTATED	2	5	4	2
ZMYM2 WILD-TYPE	66	73	27	24

'ZMYM2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.263 (Fisher's exact test), Q value = 0.69

Table S1589. Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZMYM2 MUTATED	8	6	3
ZMYM2 WILD-TYPE	71	79	80

'ZMYM2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0184 (Fisher's exact test), Q value = 0.21

Table S1590. Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZMYM2 MUTATED	1	1	2	5	6	1	1
ZMYM2 WILD-TYPE	43	40	15	28	29	30	45

Figure S286. Get High-res Image Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 0.96

Table S1591. Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZMYM2 MUTATED	4	7	5
ZMYM2 WILD-TYPE	65	72	87

'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.321 (Fisher's exact test), Q value = 0.73

Table S1592. Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZMYM2 MUTATED	8	1	4	3
ZMYM2 WILD-TYPE	65	42	75	42

'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.12 (Fisher's exact test), Q value = 0.52

Table S1593. Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZMYM2 MUTATED	2	2	1
ZMYM2 WILD-TYPE	27	17	63

'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.096 (Fisher's exact test), Q value = 0.46

Table S1594. Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZMYM2 MUTATED	3	0	2
ZMYM2 WILD-TYPE	30	48	29

'EPC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.504 (Fisher's exact test), Q value = 0.86

Table S1595. Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
EPC2 MUTATED	0	4	0	0	1
EPC2 WILD-TYPE	56	148	11	5	17

'EPC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1596. Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
EPC2 MUTATED	1	1	2
EPC2 WILD-TYPE	42	38	51

'EPC2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S1597. Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
EPC2 MUTATED	1	2	0
EPC2 WILD-TYPE	70	70	60

'EPC2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1598. Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
EPC2 MUTATED	1	2	0	0
EPC2 WILD-TYPE	67	76	31	26

'EPC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.248 (Fisher's exact test), Q value = 0.67

Table S1599. Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
EPC2 MUTATED	2	0	3
EPC2 WILD-TYPE	77	85	80

'EPC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.184 (Fisher's exact test), Q value = 0.59

Table S1600. Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
EPC2 MUTATED	0	0	1	0	1	2	1
EPC2 WILD-TYPE	44	41	16	33	34	29	45

'EPC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.274 (Fisher's exact test), Q value = 0.7

Table S1601. Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
EPC2 MUTATED	2	0	3
EPC2 WILD-TYPE	67	79	89

'EPC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.242 (Fisher's exact test), Q value = 0.66

Table S1602. Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
EPC2 MUTATED	1	0	4	0
EPC2 WILD-TYPE	72	43	75	45

'EPC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.561 (Fisher's exact test), Q value = 0.89

Table S1603. Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
EPC2 MUTATED	0	1	2
EPC2 WILD-TYPE	29	18	62

'EPC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.468 (Fisher's exact test), Q value = 0.82

Table S1604. Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
EPC2 MUTATED	2	1	0
EPC2 WILD-TYPE	31	47	31

'DEPDC1B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 0.97

Table S1605. Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
DEPDC1B MUTATED	1	2	0	0
DEPDC1B WILD-TYPE	11	16	11	10

'DEPDC1B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 0.6

Table S1606. Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
DEPDC1B MUTATED	2	0	0	1	0
DEPDC1B WILD-TYPE	10	10	7	6	15

'DEPDC1B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.179 (Fisher's exact test), Q value = 0.59

Table S1607. Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
DEPDC1B MUTATED	0	11	0	0	0
DEPDC1B WILD-TYPE	56	141	11	5	18

'DEPDC1B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 0.97

Table S1608. Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
DEPDC1B MUTATED	3	1	2
DEPDC1B WILD-TYPE	40	38	51

'DEPDC1B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.431 (Fisher's exact test), Q value = 0.79

Table S1609. Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
DEPDC1B MUTATED	6	3	2
DEPDC1B WILD-TYPE	65	69	58

'DEPDC1B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.359 (Fisher's exact test), Q value = 0.77

Table S1610. Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
DEPDC1B MUTATED	2	4	2	3
DEPDC1B WILD-TYPE	66	74	29	23

'DEPDC1B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.289 (Fisher's exact test), Q value = 0.7

Table S1611. Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
DEPDC1B MUTATED	6	3	2
DEPDC1B WILD-TYPE	73	82	81

'DEPDC1B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.102 (Fisher's exact test), Q value = 0.48

Table S1612. Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
DEPDC1B MUTATED	1	0	2	3	3	0	2
DEPDC1B WILD-TYPE	43	41	15	30	32	31	44

'DEPDC1B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.92 (Fisher's exact test), Q value = 1

Table S1613. Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
DEPDC1B MUTATED	3	4	3
DEPDC1B WILD-TYPE	66	75	89

'DEPDC1B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.145 (Fisher's exact test), Q value = 0.55

Table S1614. Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
DEPDC1B MUTATED	6	0	2	2
DEPDC1B WILD-TYPE	67	43	77	43

'DEPDC1B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.12 (Fisher's exact test), Q value = 0.52

Table S1615. Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
DEPDC1B MUTATED	2	2	1
DEPDC1B WILD-TYPE	27	17	63

'DEPDC1B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.445 (Fisher's exact test), Q value = 0.81

Table S1616. Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
DEPDC1B MUTATED	3	1	1
DEPDC1B WILD-TYPE	30	47	30

'C3AR1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 0.77

Table S1617. Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
C3AR1 MUTATED	2	1	0	0
C3AR1 WILD-TYPE	10	17	11	10

'C3AR1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 0.7

Table S1618. Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
C3AR1 MUTATED	1	0	1	1	0
C3AR1 WILD-TYPE	11	10	6	6	15

'C3AR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.498 (Fisher's exact test), Q value = 0.85

Table S1619. Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
C3AR1 MUTATED	0	7	0	0	0
C3AR1 WILD-TYPE	56	145	11	5	18

'C3AR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 0.92

Table S1620. Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
C3AR1 MUTATED	3	1	2
C3AR1 WILD-TYPE	68	71	58

'C3AR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.939 (Fisher's exact test), Q value = 1

Table S1621. Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
C3AR1 MUTATED	2	3	1	0
C3AR1 WILD-TYPE	66	75	30	26

'C3AR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 0.98

Table S1622. Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
C3AR1 MUTATED	1	3	3
C3AR1 WILD-TYPE	78	82	80

'C3AR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.168 (Fisher's exact test), Q value = 0.58

Table S1623. Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
C3AR1 MUTATED	0	0	0	2	2	0	3
C3AR1 WILD-TYPE	44	41	17	31	33	31	43

'C3AR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S1624. Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
C3AR1 MUTATED	1	2	3
C3AR1 WILD-TYPE	68	77	89

'C3AR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 0.92

Table S1625. Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
C3AR1 MUTATED	3	1	2	0
C3AR1 WILD-TYPE	70	42	77	45

'STK3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0602 (Fisher's exact test), Q value = 0.38

Table S1626. Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
STK3 MUTATED	0	7	0	0	3
STK3 WILD-TYPE	56	145	11	5	15

'STK3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S1627. Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
STK3 MUTATED	2	3	2
STK3 WILD-TYPE	41	36	51

'STK3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.739 (Fisher's exact test), Q value = 0.99

Table S1628. Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
STK3 MUTATED	2	4	2
STK3 WILD-TYPE	69	68	58

'STK3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.588 (Fisher's exact test), Q value = 0.91

Table S1629. Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
STK3 MUTATED	2	5	1	0
STK3 WILD-TYPE	66	73	30	26

'STK3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.395 (Fisher's exact test), Q value = 0.77

Table S1630. Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
STK3 MUTATED	5	2	3
STK3 WILD-TYPE	74	83	80

'STK3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0273 (Fisher's exact test), Q value = 0.26

Table S1631. Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
STK3 MUTATED	0	0	1	3	4	0	2
STK3 WILD-TYPE	44	41	16	30	31	31	44

Figure S287. Get High-res Image Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'STK3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.556 (Fisher's exact test), Q value = 0.89

Table S1632. Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
STK3 MUTATED	2	5	3
STK3 WILD-TYPE	67	74	89

'STK3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0867 (Fisher's exact test), Q value = 0.45

Table S1633. Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
STK3 MUTATED	6	0	4	0
STK3 WILD-TYPE	67	43	75	45

'STK3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0715 (Fisher's exact test), Q value = 0.42

Table S1634. Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
STK3 MUTATED	0	3	3
STK3 WILD-TYPE	29	16	61

'STK3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.492 (Fisher's exact test), Q value = 0.85

Table S1635. Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
STK3 MUTATED	1	2	3
STK3 WILD-TYPE	32	46	28

'FOXJ3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 0.77

Table S1636. Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
FOXJ3 MUTATED	2	1	0	0
FOXJ3 WILD-TYPE	10	17	11	10

'FOXJ3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 0.7

Table S1637. Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
FOXJ3 MUTATED	1	0	1	1	0
FOXJ3 WILD-TYPE	11	10	6	6	15

'FOXJ3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.349 (Fisher's exact test), Q value = 0.77

Table S1638. Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
FOXJ3 MUTATED	0	9	0	0	1
FOXJ3 WILD-TYPE	56	143	11	5	17

'FOXJ3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S1639. Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
FOXJ3 MUTATED	1	0	2
FOXJ3 WILD-TYPE	42	39	51

'FOXJ3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.394 (Fisher's exact test), Q value = 0.77

Table S1640. Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
FOXJ3 MUTATED	3	5	1
FOXJ3 WILD-TYPE	68	67	59

'FOXJ3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.921 (Fisher's exact test), Q value = 1

Table S1641. Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
FOXJ3 MUTATED	3	3	2	1
FOXJ3 WILD-TYPE	65	75	29	25

'FOXJ3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0153 (Fisher's exact test), Q value = 0.19

Table S1642. Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
FOXJ3 MUTATED	3	7	0
FOXJ3 WILD-TYPE	76	78	83

Figure S288. Get High-res Image Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'FOXJ3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00401 (Fisher's exact test), Q value = 0.076

Table S1643. Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
FOXJ3 MUTATED	0	1	1	3	5	0	0
FOXJ3 WILD-TYPE	44	40	16	30	30	31	46

Figure S289. Get High-res Image Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FOXJ3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.722 (Fisher's exact test), Q value = 0.99

Table S1644. Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
FOXJ3 MUTATED	4	3	3
FOXJ3 WILD-TYPE	65	76	89

'FOXJ3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.558 (Fisher's exact test), Q value = 0.89

Table S1645. Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
FOXJ3 MUTATED	5	2	2	1
FOXJ3 WILD-TYPE	68	41	77	44

'FOXJ3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0762 (Fisher's exact test), Q value = 0.43

Table S1646. Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
FOXJ3 MUTATED	2	1	0
FOXJ3 WILD-TYPE	27	18	64

'FOXJ3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 0.59

Table S1647. Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
FOXJ3 MUTATED	2	0	1
FOXJ3 WILD-TYPE	31	48	30

'EPS8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.654 (Fisher's exact test), Q value = 0.96

Table S1648. Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
EPS8 MUTATED	1	9	0	0	1
EPS8 WILD-TYPE	55	143	11	5	17

'EPS8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.32 (Fisher's exact test), Q value = 0.73

Table S1649. Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
EPS8 MUTATED	3	0	3
EPS8 WILD-TYPE	40	39	50

'EPS8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.716 (Fisher's exact test), Q value = 0.98

Table S1650. Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
EPS8 MUTATED	3	5	2
EPS8 WILD-TYPE	68	67	58

'EPS8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.9 (Fisher's exact test), Q value = 1

Table S1651. Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
EPS8 MUTATED	4	3	2	1
EPS8 WILD-TYPE	64	75	29	25

'EPS8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 0.82

Table S1652. Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
EPS8 MUTATED	5	5	2
EPS8 WILD-TYPE	74	80	81

'EPS8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.17 (Fisher's exact test), Q value = 0.58

Table S1653. Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
EPS8 MUTATED	1	2	1	4	3	1	0
EPS8 WILD-TYPE	43	39	16	29	32	30	46

'EPS8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.462 (Fisher's exact test), Q value = 0.82

Table S1654. Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
EPS8 MUTATED	3	6	3
EPS8 WILD-TYPE	66	73	89

'EPS8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S1655. Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
EPS8 MUTATED	4	3	3	2
EPS8 WILD-TYPE	69	40	76	43

'EPS8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.309 (Fisher's exact test), Q value = 0.72

Table S1656. Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
EPS8 MUTATED	2	2	2
EPS8 WILD-TYPE	27	17	62

'EPS8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.372 (Fisher's exact test), Q value = 0.77

Table S1657. Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
EPS8 MUTATED	2	1	3
EPS8 WILD-TYPE	31	47	28

'ZNF385B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.432 (Fisher's exact test), Q value = 0.79

Table S1658. Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF385B MUTATED	0	6	0	0	1
ZNF385B WILD-TYPE	56	146	11	5	17

'ZNF385B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.73 (Fisher's exact test), Q value = 0.99

Table S1659. Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF385B MUTATED	1	1	3
ZNF385B WILD-TYPE	42	38	50

'ZNF385B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.896 (Fisher's exact test), Q value = 1

Table S1660. Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF385B MUTATED	3	2	2
ZNF385B WILD-TYPE	68	70	58

'ZNF385B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.506 (Fisher's exact test), Q value = 0.86

Table S1661. Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF385B MUTATED	1	3	2	1
ZNF385B WILD-TYPE	67	75	29	25

'ZNF385B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 0.72

Table S1662. Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF385B MUTATED	4	2	1
ZNF385B WILD-TYPE	75	83	82

'ZNF385B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0263 (Fisher's exact test), Q value = 0.25

Table S1663. Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF385B MUTATED	0	0	0	2	4	0	1
ZNF385B WILD-TYPE	44	41	17	31	31	31	45

Figure S290. Get High-res Image Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF385B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.678 (Fisher's exact test), Q value = 0.97

Table S1664. Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF385B MUTATED	1	3	2
ZNF385B WILD-TYPE	68	76	90

'ZNF385B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.331 (Fisher's exact test), Q value = 0.74

Table S1665. Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF385B MUTATED	4	0	1	1
ZNF385B WILD-TYPE	69	43	78	44

'EFCAB4B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 0.82

Table S1666. Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
EFCAB4B MUTATED	1	8	0	0	2
EFCAB4B WILD-TYPE	55	144	11	5	16

'EFCAB4B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S1667. Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
EFCAB4B MUTATED	2	1	3
EFCAB4B WILD-TYPE	41	38	50

'EFCAB4B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0166 (Fisher's exact test), Q value = 0.19

Table S1668. Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
EFCAB4B MUTATED	1	8	1
EFCAB4B WILD-TYPE	70	64	59

Figure S291. Get High-res Image Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'EFCAB4B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.583 (Fisher's exact test), Q value = 0.91

Table S1669. Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
EFCAB4B MUTATED	3	6	1	0
EFCAB4B WILD-TYPE	65	72	30	26

'EFCAB4B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 0.97

Table S1670. Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
EFCAB4B MUTATED	5	3	3
EFCAB4B WILD-TYPE	74	82	80

'EFCAB4B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0544 (Fisher's exact test), Q value = 0.36

Table S1671. Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
EFCAB4B MUTATED	0	1	0	4	4	1	1
EFCAB4B WILD-TYPE	44	40	17	29	31	30	45

'EFCAB4B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.635 (Fisher's exact test), Q value = 0.95

Table S1672. Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
EFCAB4B MUTATED	2	5	4
EFCAB4B WILD-TYPE	67	74	88

'EFCAB4B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.363 (Fisher's exact test), Q value = 0.77

Table S1673. Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
EFCAB4B MUTATED	4	3	4	0
EFCAB4B WILD-TYPE	69	40	75	45

'EFCAB4B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 0.59

Table S1674. Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
EFCAB4B MUTATED	0	2	2
EFCAB4B WILD-TYPE	29	17	62

'EFCAB4B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0356 (Fisher's exact test), Q value = 0.3

Table S1675. Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
EFCAB4B MUTATED	1	0	3
EFCAB4B WILD-TYPE	32	48	28

Figure S292. Get High-res Image Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NPRL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.686 (Fisher's exact test), Q value = 0.97

Table S1676. Gene #156: 'NPRL2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
NPRL2 MUTATED	0	5	0	0	0
NPRL2 WILD-TYPE	56	147	11	5	18

'NPRL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.46 (Fisher's exact test), Q value = 0.82

Table S1677. Gene #156: 'NPRL2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
NPRL2 MUTATED	0	2	2
NPRL2 WILD-TYPE	71	70	58

'NPRL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.161 (Fisher's exact test), Q value = 0.58

Table S1678. Gene #156: 'NPRL2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
NPRL2 MUTATED	0	2	2	0
NPRL2 WILD-TYPE	68	76	29	26

'NPRL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1679. Gene #156: 'NPRL2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
NPRL2 MUTATED	1	2	2
NPRL2 WILD-TYPE	78	83	81

'NPRL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.535 (Fisher's exact test), Q value = 0.88

Table S1680. Gene #156: 'NPRL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
NPRL2 MUTATED	0	0	0	1	2	1	1
NPRL2 WILD-TYPE	44	41	17	32	33	30	45

'NPRL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.326 (Fisher's exact test), Q value = 0.74

Table S1681. Gene #156: 'NPRL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
NPRL2 MUTATED	0	3	2
NPRL2 WILD-TYPE	69	76	90

'NPRL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.401 (Fisher's exact test), Q value = 0.77

Table S1682. Gene #156: 'NPRL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
NPRL2 MUTATED	3	0	2	0
NPRL2 WILD-TYPE	70	43	77	45

'ATF6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 0.64

Table S1683. Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ATF6 MUTATED	3	1	2	0
ATF6 WILD-TYPE	9	17	9	10

'ATF6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.192 (Fisher's exact test), Q value = 0.59

Table S1684. Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ATF6 MUTATED	1	0	2	2	1
ATF6 WILD-TYPE	11	10	5	5	14

'ATF6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 0.52

Table S1685. Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ATF6 MUTATED	0	11	1	0	2
ATF6 WILD-TYPE	56	141	10	5	16

'ATF6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S1686. Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ATF6 MUTATED	2	1	3
ATF6 WILD-TYPE	41	38	50

'ATF6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.869 (Fisher's exact test), Q value = 1

Table S1687. Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ATF6 MUTATED	5	4	3
ATF6 WILD-TYPE	66	68	57

'ATF6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.365 (Fisher's exact test), Q value = 0.77

Table S1688. Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ATF6 MUTATED	3	6	3	0
ATF6 WILD-TYPE	65	72	28	26

'ATF6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.942 (Fisher's exact test), Q value = 1

Table S1689. Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ATF6 MUTATED	5	5	4
ATF6 WILD-TYPE	74	80	79

'ATF6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.15 (Fisher's exact test), Q value = 0.55

Table S1690. Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ATF6 MUTATED	0	1	2	3	4	2	2
ATF6 WILD-TYPE	44	40	15	30	31	29	44

'ATF6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 0.59

Table S1691. Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ATF6 MUTATED	5	6	2
ATF6 WILD-TYPE	64	73	90

'ATF6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.119 (Fisher's exact test), Q value = 0.52

Table S1692. Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ATF6 MUTATED	8	2	2	1
ATF6 WILD-TYPE	65	41	77	44

'ATF6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.039 (Fisher's exact test), Q value = 0.31

Table S1693. Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ATF6 MUTATED	4	1	1
ATF6 WILD-TYPE	25	18	63

Figure S293. Get High-res Image Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'ATF6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.171 (Fisher's exact test), Q value = 0.58

Table S1694. Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ATF6 MUTATED	4	1	1
ATF6 WILD-TYPE	29	47	30

'LIMA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 0.98

Table S1695. Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
LIMA1 MUTATED	1	6	0	0	1
LIMA1 WILD-TYPE	55	146	11	5	17

'LIMA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.384 (Fisher's exact test), Q value = 0.77

Table S1696. Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
LIMA1 MUTATED	1	0	3
LIMA1 WILD-TYPE	42	39	50

'LIMA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 0.92

Table S1697. Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
LIMA1 MUTATED	3	4	1
LIMA1 WILD-TYPE	68	68	59

'LIMA1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.524 (Fisher's exact test), Q value = 0.87

Table S1698. Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
LIMA1 MUTATED	1	4	2	1
LIMA1 WILD-TYPE	67	74	29	25

'LIMA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0258 (Fisher's exact test), Q value = 0.25

Table S1699. Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
LIMA1 MUTATED	2	6	0
LIMA1 WILD-TYPE	77	79	83

Figure S294. Get High-res Image Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'LIMA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0026 (Fisher's exact test), Q value = 0.056

Table S1700. Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
LIMA1 MUTATED	0	0	1	4	3	0	0
LIMA1 WILD-TYPE	44	41	16	29	32	31	46

Figure S295. Get High-res Image Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'LIMA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.604 (Fisher's exact test), Q value = 0.92

Table S1701. Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
LIMA1 MUTATED	2	4	2
LIMA1 WILD-TYPE	67	75	90

'LIMA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00011 (Fisher's exact test), Q value = 0.0058

Table S1702. Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
LIMA1 MUTATED	8	0	0	0
LIMA1 WILD-TYPE	65	43	79	45

Figure S296. Get High-res Image Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PPIG MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.194 (Fisher's exact test), Q value = 0.59

Table S1703. Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
PPIG MUTATED	3	2	0	0
PPIG WILD-TYPE	9	16	11	10

'PPIG MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0918 (Fisher's exact test), Q value = 0.46

Table S1704. Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
PPIG MUTATED	2	0	1	2	0
PPIG WILD-TYPE	10	10	6	5	15

'PPIG MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0415 (Fisher's exact test), Q value = 0.32

Table S1705. Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PPIG MUTATED	0	16	0	0	0
PPIG WILD-TYPE	56	136	11	5	18

Figure S297. Get High-res Image Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PPIG MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1706. Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PPIG MUTATED	3	2	4
PPIG WILD-TYPE	40	37	49

'PPIG MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.892 (Fisher's exact test), Q value = 1

Table S1707. Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PPIG MUTATED	6	5	4
PPIG WILD-TYPE	65	67	56

'PPIG MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.979 (Fisher's exact test), Q value = 1

Table S1708. Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PPIG MUTATED	6	5	2	2
PPIG WILD-TYPE	62	73	29	24

'PPIG MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 0.55

Table S1709. Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PPIG MUTATED	6	8	2
PPIG WILD-TYPE	73	77	81

'PPIG MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00195 (Fisher's exact test), Q value = 0.047

Table S1710. Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PPIG MUTATED	1	1	1	7	5	0	1
PPIG WILD-TYPE	43	40	16	26	30	31	45

Figure S298. Get High-res Image Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PPIG MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0919 (Fisher's exact test), Q value = 0.46

Table S1711. Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PPIG MUTATED	2	9	4
PPIG WILD-TYPE	67	70	88

'PPIG MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.244 (Fisher's exact test), Q value = 0.66

Table S1712. Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PPIG MUTATED	8	1	3	3
PPIG WILD-TYPE	65	42	76	42

'PPIG MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.232 (Fisher's exact test), Q value = 0.64

Table S1713. Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
PPIG MUTATED	2	3	3
PPIG WILD-TYPE	27	16	61

'PPIG MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0531 (Fisher's exact test), Q value = 0.35

Table S1714. Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
PPIG MUTATED	2	1	5
PPIG WILD-TYPE	31	47	26

'ZNF774 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.67 (Fisher's exact test), Q value = 0.97

Table S1715. Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF774 MUTATED	1	9	0	0	0
ZNF774 WILD-TYPE	55	143	11	5	18

'ZNF774 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 0.97

Table S1716. Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF774 MUTATED	3	1	2
ZNF774 WILD-TYPE	40	38	51

'ZNF774 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 0.79

Table S1717. Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF774 MUTATED	4	5	1
ZNF774 WILD-TYPE	67	67	59

'ZNF774 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.707 (Fisher's exact test), Q value = 0.98

Table S1718. Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF774 MUTATED	3	5	2	0
ZNF774 WILD-TYPE	65	73	29	26

'ZNF774 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.52 (Fisher's exact test), Q value = 0.87

Table S1719. Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF774 MUTATED	3	5	2
ZNF774 WILD-TYPE	76	80	81

'ZNF774 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.134 (Fisher's exact test), Q value = 0.53

Table S1720. Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF774 MUTATED	1	0	1	4	2	0	2
ZNF774 WILD-TYPE	43	41	16	29	33	31	44

'ZNF774 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 0.77

Table S1721. Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF774 MUTATED	3	5	2
ZNF774 WILD-TYPE	66	74	90

'ZNF774 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.314 (Fisher's exact test), Q value = 0.72

Table S1722. Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF774 MUTATED	6	1	2	1
ZNF774 WILD-TYPE	67	42	77	44

'ZNF774 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.518 (Fisher's exact test), Q value = 0.87

Table S1723. Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZNF774 MUTATED	1	2	3
ZNF774 WILD-TYPE	28	17	61

'ZNF774 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.172 (Fisher's exact test), Q value = 0.58

Table S1724. Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZNF774 MUTATED	4	1	1
ZNF774 WILD-TYPE	29	47	30

'MUTED MUTATION STATUS' versus 'CN_CNMF'

P value = 0.43 (Fisher's exact test), Q value = 0.79

Table S1725. Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MUTED MUTATED	0	6	0	0	1
MUTED WILD-TYPE	56	146	11	5	17

'MUTED MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.629 (Fisher's exact test), Q value = 0.95

Table S1726. Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MUTED MUTATED	0	1	2
MUTED WILD-TYPE	43	38	51

'MUTED MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.332 (Fisher's exact test), Q value = 0.74

Table S1727. Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MUTED MUTATED	4	1	1
MUTED WILD-TYPE	67	71	59

'MUTED MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.374 (Fisher's exact test), Q value = 0.77

Table S1728. Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MUTED MUTATED	2	1	2	1
MUTED WILD-TYPE	66	77	29	25

'MUTED MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 0.98

Table S1729. Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MUTED MUTATED	1	3	3
MUTED WILD-TYPE	78	82	80

'MUTED MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.117 (Fisher's exact test), Q value = 0.52

Table S1730. Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MUTED MUTATED	0	0	0	2	3	0	2
MUTED WILD-TYPE	44	41	17	31	32	31	44

'MUTED MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.446 (Fisher's exact test), Q value = 0.81

Table S1731. Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MUTED MUTATED	1	1	4
MUTED WILD-TYPE	68	78	88

'MUTED MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.424 (Fisher's exact test), Q value = 0.79

Table S1732. Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MUTED MUTATED	3	0	3	0
MUTED WILD-TYPE	70	43	76	45

'TPX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 0.79

Table S1733. Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
TPX2 MUTATED	0	5	0	0	1
TPX2 WILD-TYPE	56	147	11	5	17

'TPX2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S1734. Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
TPX2 MUTATED	2	1	1
TPX2 WILD-TYPE	41	38	52

'TPX2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0511 (Fisher's exact test), Q value = 0.35

Table S1735. Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
TPX2 MUTATED	1	5	0
TPX2 WILD-TYPE	70	67	60

'TPX2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.197 (Fisher's exact test), Q value = 0.59

Table S1736. Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
TPX2 MUTATED	0	4	1	1
TPX2 WILD-TYPE	68	74	30	25

'TPX2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0854 (Fisher's exact test), Q value = 0.44

Table S1737. Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
TPX2 MUTATED	4	2	0
TPX2 WILD-TYPE	75	83	83

'TPX2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.158 (Fisher's exact test), Q value = 0.57

Table S1738. Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
TPX2 MUTATED	1	0	1	2	2	0	0
TPX2 WILD-TYPE	43	41	16	31	33	31	46

'TPX2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0187 (Fisher's exact test), Q value = 0.21

Table S1739. Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
TPX2 MUTATED	1	5	0
TPX2 WILD-TYPE	68	74	92

Figure S299. Get High-res Image Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'TPX2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.136 (Fisher's exact test), Q value = 0.53

Table S1740. Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
TPX2 MUTATED	4	1	0	1
TPX2 WILD-TYPE	69	42	79	44

'TPX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0416 (Fisher's exact test), Q value = 0.32

Table S1741. Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
TPX2 MUTATED	1	2	0
TPX2 WILD-TYPE	28	17	64

Figure S300. Get High-res Image Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'TPX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 0.59

Table S1742. Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
TPX2 MUTATED	2	0	1
TPX2 WILD-TYPE	31	48	30

'PARG MUTATION STATUS' versus 'CN_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 0.51

Table S1743. Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PARG MUTATED	0	7	0	1	1
PARG WILD-TYPE	56	145	11	4	17

'PARG MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S1744. Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PARG MUTATED	2	1	3
PARG WILD-TYPE	41	38	50

'PARG MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1745. Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PARG MUTATED	3	3	2
PARG WILD-TYPE	68	69	58

'PARG MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.61 (Fisher's exact test), Q value = 0.93

Table S1746. Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PARG MUTATED	2	4	2	0
PARG WILD-TYPE	66	74	29	26

'PARG MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.6

Table S1747. Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PARG MUTATED	5	3	1
PARG WILD-TYPE	74	82	82

'PARG MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00833 (Fisher's exact test), Q value = 0.12

Table S1748. Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PARG MUTATED	0	0	1	3	4	1	0
PARG WILD-TYPE	44	41	16	30	31	30	46

Figure S301. Get High-res Image Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PARG MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 0.57

Table S1749. Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PARG MUTATED	3	5	1
PARG WILD-TYPE	66	74	91

'PARG MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0795 (Fisher's exact test), Q value = 0.43

Table S1750. Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PARG MUTATED	6	0	1	2
PARG WILD-TYPE	67	43	78	43

'PARG MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.041 (Fisher's exact test), Q value = 0.32

Table S1751. Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
PARG MUTATED	2	2	0
PARG WILD-TYPE	27	17	64

Figure S302. Get High-res Image Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'PARG MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.169 (Fisher's exact test), Q value = 0.58

Table S1752. Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
PARG MUTATED	2	0	2
PARG WILD-TYPE	31	48	29

'PSMD3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 0.97

Table S1753. Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
PSMD3 MUTATED	1	2	0	0
PSMD3 WILD-TYPE	11	16	11	10

'PSMD3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.206 (Fisher's exact test), Q value = 0.6

Table S1754. Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
PSMD3 MUTATED	2	0	0	1	0
PSMD3 WILD-TYPE	10	10	7	6	15

'PSMD3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 0.77

Table S1755. Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PSMD3 MUTATED	0	9	0	0	1
PSMD3 WILD-TYPE	56	143	11	5	17

'PSMD3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.518 (Fisher's exact test), Q value = 0.87

Table S1756. Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PSMD3 MUTATED	3	1	1
PSMD3 WILD-TYPE	40	38	52

'PSMD3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.479 (Fisher's exact test), Q value = 0.84

Table S1757. Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PSMD3 MUTATED	4	4	1
PSMD3 WILD-TYPE	67	68	59

'PSMD3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.391 (Fisher's exact test), Q value = 0.77

Table S1758. Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PSMD3 MUTATED	3	3	3	0
PSMD3 WILD-TYPE	65	75	28	26

'PSMD3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.47 (Fisher's exact test), Q value = 0.83

Table S1759. Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PSMD3 MUTATED	5	4	2
PSMD3 WILD-TYPE	74	81	81

'PSMD3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0175 (Fisher's exact test), Q value = 0.2

Table S1760. Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PSMD3 MUTATED	0	2	3	3	1	2	0
PSMD3 WILD-TYPE	44	39	14	30	34	29	46

Figure S303. Get High-res Image Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PSMD3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.74 (Fisher's exact test), Q value = 0.99

Table S1761. Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PSMD3 MUTATED	4	4	3
PSMD3 WILD-TYPE	65	75	89

'PSMD3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.973 (Fisher's exact test), Q value = 1

Table S1762. Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PSMD3 MUTATED	4	2	3	2
PSMD3 WILD-TYPE	69	41	76	43

'PSMD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 0.53

Table S1763. Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
PSMD3 MUTATED	1	2	1
PSMD3 WILD-TYPE	28	17	63

'PSMD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.814 (Fisher's exact test), Q value = 1

Table S1764. Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
PSMD3 MUTATED	2	1	1
PSMD3 WILD-TYPE	31	47	30

'STRN3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.622 (Fisher's exact test), Q value = 0.94

Table S1765. Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
STRN3 MUTATED	1	10	0	0	1
STRN3 WILD-TYPE	55	142	11	5	17

'STRN3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.716 (Fisher's exact test), Q value = 0.98

Table S1766. Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
STRN3 MUTATED	3	1	3
STRN3 WILD-TYPE	40	38	50

'STRN3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.704 (Fisher's exact test), Q value = 0.98

Table S1767. Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
STRN3 MUTATED	5	5	2
STRN3 WILD-TYPE	66	67	58

'STRN3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.736 (Fisher's exact test), Q value = 0.99

Table S1768. Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
STRN3 MUTATED	3	5	3	1
STRN3 WILD-TYPE	65	73	28	25

'STRN3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 0.53

Table S1769. Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
STRN3 MUTATED	6	5	1
STRN3 WILD-TYPE	73	80	82

'STRN3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0509 (Fisher's exact test), Q value = 0.35

Table S1770. Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
STRN3 MUTATED	2	0	1	4	4	0	1
STRN3 WILD-TYPE	42	41	16	29	31	31	45

'STRN3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0227 (Fisher's exact test), Q value = 0.23

Table S1771. Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
STRN3 MUTATED	3	8	1
STRN3 WILD-TYPE	66	71	91

Figure S304. Get High-res Image Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'STRN3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0886 (Fisher's exact test), Q value = 0.46

Table S1772. Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
STRN3 MUTATED	6	1	1	4
STRN3 WILD-TYPE	67	42	78	41

'STRN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.119 (Fisher's exact test), Q value = 0.52

Table S1773. Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
STRN3 MUTATED	2	2	1
STRN3 WILD-TYPE	27	17	63

'STRN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.095 (Fisher's exact test), Q value = 0.46

Table S1774. Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
STRN3 MUTATED	3	0	2
STRN3 WILD-TYPE	30	48	29

'MLL4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.685 (Fisher's exact test), Q value = 0.97

Table S1775. Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
MLL4 MUTATED	2	1	1	0
MLL4 WILD-TYPE	10	17	10	10

'MLL4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0915 (Fisher's exact test), Q value = 0.46

Table S1776. Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
MLL4 MUTATED	1	0	2	1	0
MLL4 WILD-TYPE	11	10	5	6	15

'MLL4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0015 (Fisher's exact test), Q value = 0.039

Table S1777. Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MLL4 MUTATED	0	27	0	0	2
MLL4 WILD-TYPE	56	125	11	5	16

Figure S305. Get High-res Image Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'MLL4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0393 (Fisher's exact test), Q value = 0.31

Table S1778. Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MLL4 MUTATED	4	2	12
MLL4 WILD-TYPE	39	37	41

Figure S306. Get High-res Image Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'MLL4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.233 (Fisher's exact test), Q value = 0.64

Table S1779. Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MLL4 MUTATED	7	10	3
MLL4 WILD-TYPE	64	62	57

'MLL4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.15 (Fisher's exact test), Q value = 0.55

Table S1780. Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MLL4 MUTATED	4	9	6	1
MLL4 WILD-TYPE	64	69	25	25

'MLL4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.459 (Fisher's exact test), Q value = 0.82

Table S1781. Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MLL4 MUTATED	7	13	10
MLL4 WILD-TYPE	72	72	73

'MLL4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00058 (Fisher's exact test), Q value = 0.019

Table S1782. Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MLL4 MUTATED	0	2	2	10	6	6	4
MLL4 WILD-TYPE	44	39	15	23	29	25	42

Figure S307. Get High-res Image Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MLL4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 0.57

Table S1783. Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MLL4 MUTATED	4	10	14
MLL4 WILD-TYPE	65	69	78

'MLL4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0122 (Fisher's exact test), Q value = 0.17

Table S1784. Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MLL4 MUTATED	14	2	11	1
MLL4 WILD-TYPE	59	41	68	44

Figure S308. Get High-res Image Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'MLL4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 0.77

Table S1785. Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MLL4 MUTATED	2	4	8
MLL4 WILD-TYPE	27	15	56

'MLL4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.718 (Fisher's exact test), Q value = 0.98

Table S1786. Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MLL4 MUTATED	4	5	5
MLL4 WILD-TYPE	29	43	26

'MSN MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.806 (Fisher's exact test), Q value = 1

Table S1787. Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
MSN MUTATED	2	2	1	0
MSN WILD-TYPE	10	16	10	10

'MSN MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.213 (Fisher's exact test), Q value = 0.61

Table S1788. Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
MSN MUTATED	1	1	2	1	0
MSN WILD-TYPE	11	9	5	6	15

'MSN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.937 (Fisher's exact test), Q value = 1

Table S1789. Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MSN MUTATED	3	10	1	0	1
MSN WILD-TYPE	53	142	10	5	17

'MSN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0237 (Fisher's exact test), Q value = 0.23

Table S1790. Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MSN MUTATED	5	0	1
MSN WILD-TYPE	38	39	52

Figure S309. Get High-res Image Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'MSN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.42 (Fisher's exact test), Q value = 0.79

Table S1791. Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MSN MUTATED	2	5	5
MSN WILD-TYPE	69	67	55

'MSN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.164 (Fisher's exact test), Q value = 0.58

Table S1792. Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MSN MUTATED	1	6	3	2
MSN WILD-TYPE	67	72	28	24

'MSN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0436 (Fisher's exact test), Q value = 0.32

Table S1793. Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MSN MUTATED	8	6	1
MSN WILD-TYPE	71	79	82

Figure S310. Get High-res Image Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'MSN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0281 (Fisher's exact test), Q value = 0.26

Table S1794. Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MSN MUTATED	2	1	3	4	4	1	0
MSN WILD-TYPE	42	40	14	29	31	30	46

Figure S311. Get High-res Image Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MSN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 0.59

Table S1795. Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MSN MUTATED	5	6	2
MSN WILD-TYPE	64	73	90

'MSN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.163 (Fisher's exact test), Q value = 0.58

Table S1796. Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MSN MUTATED	6	3	1	3
MSN WILD-TYPE	67	40	78	42

'MSN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0407 (Fisher's exact test), Q value = 0.31

Table S1797. Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MSN MUTATED	2	2	0
MSN WILD-TYPE	27	17	64

Figure S312. Get High-res Image Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'MSN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0636 (Fisher's exact test), Q value = 0.39

Table S1798. Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MSN MUTATED	3	0	1
MSN WILD-TYPE	30	48	30

'MAPK8 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 0.77

Table S1799. Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
MAPK8 MUTATED	2	1	2	0
MAPK8 WILD-TYPE	10	17	9	10

'MAPK8 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.401 (Fisher's exact test), Q value = 0.77

Table S1800. Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
MAPK8 MUTATED	1	0	1	2	1
MAPK8 WILD-TYPE	11	10	6	5	14

'MAPK8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.46 (Fisher's exact test), Q value = 0.82

Table S1801. Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MAPK8 MUTATED	1	8	0	0	2
MAPK8 WILD-TYPE	55	144	11	5	16

'MAPK8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.552 (Fisher's exact test), Q value = 0.89

Table S1802. Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MAPK8 MUTATED	2	0	2
MAPK8 WILD-TYPE	41	39	51

'MAPK8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.903 (Fisher's exact test), Q value = 1

Table S1803. Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MAPK8 MUTATED	2	3	3
MAPK8 WILD-TYPE	69	69	57

'MAPK8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.615 (Fisher's exact test), Q value = 0.93

Table S1804. Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MAPK8 MUTATED	2	4	2	0
MAPK8 WILD-TYPE	66	74	29	26

'MAPK8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.929 (Fisher's exact test), Q value = 1

Table S1805. Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MAPK8 MUTATED	4	4	3
MAPK8 WILD-TYPE	75	81	80

'MAPK8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0433 (Fisher's exact test), Q value = 0.32

Table S1806. Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MAPK8 MUTATED	0	0	2	3	3	2	1
MAPK8 WILD-TYPE	44	41	15	30	32	29	45

Figure S313. Get High-res Image Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MAPK8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.92 (Fisher's exact test), Q value = 1

Table S1807. Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MAPK8 MUTATED	3	4	3
MAPK8 WILD-TYPE	66	75	89

'MAPK8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.18 (Fisher's exact test), Q value = 0.59

Table S1808. Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MAPK8 MUTATED	6	0	3	1
MAPK8 WILD-TYPE	67	43	76	44

'MAPK8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 0.69

Table S1809. Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MAPK8 MUTATED	2	1	1
MAPK8 WILD-TYPE	27	18	63

'MAPK8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.167 (Fisher's exact test), Q value = 0.58

Table S1810. Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MAPK8 MUTATED	2	0	2
MAPK8 WILD-TYPE	31	48	29

'RBL2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.535 (Fisher's exact test), Q value = 0.88

Table S1811. Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
RBL2 MUTATED	2	2	0	0
RBL2 WILD-TYPE	10	16	11	10

'RBL2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 0.67

Table S1812. Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
RBL2 MUTATED	2	0	1	1	0
RBL2 WILD-TYPE	10	10	6	6	15

'RBL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 0.55

Table S1813. Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
RBL2 MUTATED	0	10	0	0	2
RBL2 WILD-TYPE	56	142	11	5	16

'RBL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.86 (Fisher's exact test), Q value = 1

Table S1814. Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
RBL2 MUTATED	1	2	2
RBL2 WILD-TYPE	42	37	51

'RBL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.433 (Fisher's exact test), Q value = 0.79

Table S1815. Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
RBL2 MUTATED	6	3	2
RBL2 WILD-TYPE	65	69	58

'RBL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.732 (Fisher's exact test), Q value = 0.99

Table S1816. Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
RBL2 MUTATED	4	5	2	0
RBL2 WILD-TYPE	64	73	29	26

'RBL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 0.77

Table S1817. Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
RBL2 MUTATED	4	6	2
RBL2 WILD-TYPE	75	79	81

'RBL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00195 (Fisher's exact test), Q value = 0.047

Table S1818. Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
RBL2 MUTATED	0	0	0	5	5	1	1
RBL2 WILD-TYPE	44	41	17	28	30	30	45

Figure S314. Get High-res Image Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RBL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.147 (Fisher's exact test), Q value = 0.55

Table S1819. Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
RBL2 MUTATED	3	7	2
RBL2 WILD-TYPE	66	72	90

'RBL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.286 (Fisher's exact test), Q value = 0.7

Table S1820. Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
RBL2 MUTATED	7	1	3	1
RBL2 WILD-TYPE	66	42	76	44

'RBL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.498 (Fisher's exact test), Q value = 0.85

Table S1821. Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
RBL2 MUTATED	0	1	3
RBL2 WILD-TYPE	29	18	61

'RBL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1822. Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
RBL2 MUTATED	1	2	1
RBL2 WILD-TYPE	32	46	30

'PDGFRA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 0.53

Table S1823. Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PDGFRA MUTATED	0	9	1	0	2
PDGFRA WILD-TYPE	56	143	10	5	16

'PDGFRA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.189 (Fisher's exact test), Q value = 0.59

Table S1824. Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PDGFRA MUTATED	1	0	4
PDGFRA WILD-TYPE	42	39	49

'PDGFRA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1825. Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PDGFRA MUTATED	3	4	3
PDGFRA WILD-TYPE	68	68	57

'PDGFRA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.553 (Fisher's exact test), Q value = 0.89

Table S1826. Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PDGFRA MUTATED	2	4	3	1
PDGFRA WILD-TYPE	66	74	28	25

'PDGFRA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.466 (Fisher's exact test), Q value = 0.82

Table S1827. Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PDGFRA MUTATED	5	5	2
PDGFRA WILD-TYPE	74	80	81

'PDGFRA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00037 (Fisher's exact test), Q value = 0.013

Table S1828. Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PDGFRA MUTATED	0	0	1	4	6	1	0
PDGFRA WILD-TYPE	44	41	16	29	29	30	46

Figure S315. Get High-res Image Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.243 (Fisher's exact test), Q value = 0.66

Table S1829. Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PDGFRA MUTATED	3	6	2
PDGFRA WILD-TYPE	66	73	90

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.733 (Fisher's exact test), Q value = 0.99

Table S1830. Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PDGFRA MUTATED	5	1	3	2
PDGFRA WILD-TYPE	68	42	76	43

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.392 (Fisher's exact test), Q value = 0.77

Table S1831. Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
PDGFRA MUTATED	1	1	1
PDGFRA WILD-TYPE	28	18	63

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.356 (Fisher's exact test), Q value = 0.77

Table S1832. Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
PDGFRA MUTATED	0	1	2
PDGFRA WILD-TYPE	33	47	29

'TMEM62 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.373 (Fisher's exact test), Q value = 0.77

Table S1833. Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
TMEM62 MUTATED	0	8	0	0	1
TMEM62 WILD-TYPE	56	144	11	5	17

'TMEM62 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S1834. Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
TMEM62 MUTATED	1	0	2
TMEM62 WILD-TYPE	42	39	51

'TMEM62 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.207 (Fisher's exact test), Q value = 0.6

Table S1835. Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
TMEM62 MUTATED	3	4	0
TMEM62 WILD-TYPE	68	68	60

'TMEM62 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1836. Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
TMEM62 MUTATED	2	3	1	1
TMEM62 WILD-TYPE	66	75	30	25

'TMEM62 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.139 (Fisher's exact test), Q value = 0.54

Table S1837. Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
TMEM62 MUTATED	2	6	1
TMEM62 WILD-TYPE	77	79	82

'TMEM62 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0462 (Fisher's exact test), Q value = 0.33

Table S1838. Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
TMEM62 MUTATED	0	1	0	4	3	0	1
TMEM62 WILD-TYPE	44	40	17	29	32	31	45

Figure S316. Get High-res Image Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TMEM62 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 0.97

Table S1839. Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
TMEM62 MUTATED	1	3	4
TMEM62 WILD-TYPE	68	76	88

'TMEM62 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.239 (Fisher's exact test), Q value = 0.65

Table S1840. Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
TMEM62 MUTATED	5	1	2	0
TMEM62 WILD-TYPE	68	42	77	45

'RG9MTD3 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1841. Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
RG9MTD3 MUTATED	2	6	0	0	0
RG9MTD3 WILD-TYPE	54	146	11	5	18

'RG9MTD3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.557 (Fisher's exact test), Q value = 0.89

Table S1842. Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
RG9MTD3 MUTATED	2	0	2
RG9MTD3 WILD-TYPE	41	39	51

'RG9MTD3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S1843. Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
RG9MTD3 MUTATED	3	2	3
RG9MTD3 WILD-TYPE	68	70	57

'RG9MTD3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.301 (Fisher's exact test), Q value = 0.71

Table S1844. Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
RG9MTD3 MUTATED	2	3	3	0
RG9MTD3 WILD-TYPE	66	75	28	26

'RG9MTD3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.447 (Fisher's exact test), Q value = 0.81

Table S1845. Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
RG9MTD3 MUTATED	3	4	1
RG9MTD3 WILD-TYPE	76	81	82

'RG9MTD3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0367 (Fisher's exact test), Q value = 0.3

Table S1846. Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
RG9MTD3 MUTATED	1	0	1	3	3	0	0
RG9MTD3 WILD-TYPE	43	41	16	30	32	31	46

Figure S317. Get High-res Image Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RG9MTD3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.737 (Fisher's exact test), Q value = 0.99

Table S1847. Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
RG9MTD3 MUTATED	3	3	2
RG9MTD3 WILD-TYPE	66	76	90

'RG9MTD3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.171 (Fisher's exact test), Q value = 0.58

Table S1848. Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
RG9MTD3 MUTATED	4	0	1	3
RG9MTD3 WILD-TYPE	69	43	78	42

'RG9MTD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.239 (Fisher's exact test), Q value = 0.65

Table S1849. Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
RG9MTD3 MUTATED	2	0	1
RG9MTD3 WILD-TYPE	27	19	63

'RG9MTD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.182 (Fisher's exact test), Q value = 0.59

Table S1850. Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
RG9MTD3 MUTATED	2	0	1
RG9MTD3 WILD-TYPE	31	48	30

'KANK4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0606 (Fisher's exact test), Q value = 0.38

Table S1851. Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
KANK4 MUTATED	0	7	0	0	3
KANK4 WILD-TYPE	56	145	11	5	15

'KANK4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.388 (Fisher's exact test), Q value = 0.77

Table S1852. Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
KANK4 MUTATED	2	1	5
KANK4 WILD-TYPE	41	38	48

'KANK4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.716 (Fisher's exact test), Q value = 0.98

Table S1853. Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
KANK4 MUTATED	3	5	2
KANK4 WILD-TYPE	68	67	58

'KANK4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.397 (Fisher's exact test), Q value = 0.77

Table S1854. Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
KANK4 MUTATED	2	6	2	0
KANK4 WILD-TYPE	66	72	29	26

'KANK4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.288 (Fisher's exact test), Q value = 0.7

Table S1855. Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
KANK4 MUTATED	6	3	2
KANK4 WILD-TYPE	73	82	81

'KANK4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.133 (Fisher's exact test), Q value = 0.53

Table S1856. Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
KANK4 MUTATED	0	1	1	3	4	1	1
KANK4 WILD-TYPE	44	40	16	30	31	30	45

'KANK4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.92 (Fisher's exact test), Q value = 1

Table S1857. Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
KANK4 MUTATED	3	4	3
KANK4 WILD-TYPE	66	75	89

'KANK4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.177 (Fisher's exact test), Q value = 0.58

Table S1858. Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
KANK4 MUTATED	6	0	3	1
KANK4 WILD-TYPE	67	43	76	44

'KANK4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1859. Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
KANK4 MUTATED	2	1	4
KANK4 WILD-TYPE	27	18	60

'KANK4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.554 (Fisher's exact test), Q value = 0.89

Table S1860. Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
KANK4 MUTATED	2	2	3
KANK4 WILD-TYPE	31	46	28

'MYOM1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.479 (Fisher's exact test), Q value = 0.84

Table S1861. Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
MYOM1 MUTATED	3	1	1	1
MYOM1 WILD-TYPE	9	17	10	9

'MYOM1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.094 (Fisher's exact test), Q value = 0.46

Table S1862. Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
MYOM1 MUTATED	1	0	3	1	1
MYOM1 WILD-TYPE	11	10	4	6	14

'MYOM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.57 (Fisher's exact test), Q value = 0.89

Table S1863. Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MYOM1 MUTATED	3	18	0	0	2
MYOM1 WILD-TYPE	53	134	11	5	16

'MYOM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.352 (Fisher's exact test), Q value = 0.77

Table S1864. Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MYOM1 MUTATED	6	3	3
MYOM1 WILD-TYPE	37	36	50

'MYOM1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.233 (Fisher's exact test), Q value = 0.64

Table S1865. Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MYOM1 MUTATED	7	10	3
MYOM1 WILD-TYPE	64	62	57

'MYOM1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.485 (Fisher's exact test), Q value = 0.84

Table S1866. Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MYOM1 MUTATED	5	10	4	1
MYOM1 WILD-TYPE	63	68	27	25

'MYOM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0734 (Fisher's exact test), Q value = 0.42

Table S1867. Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MYOM1 MUTATED	10	10	3
MYOM1 WILD-TYPE	69	75	80

'MYOM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.102 (Fisher's exact test), Q value = 0.48

Table S1868. Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MYOM1 MUTATED	2	3	2	6	6	3	1
MYOM1 WILD-TYPE	42	38	15	27	29	28	45

'MYOM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.523 (Fisher's exact test), Q value = 0.87

Table S1869. Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MYOM1 MUTATED	7	9	6
MYOM1 WILD-TYPE	62	70	86

'MYOM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0281 (Fisher's exact test), Q value = 0.26

Table S1870. Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MYOM1 MUTATED	13	3	3	3
MYOM1 WILD-TYPE	60	40	76	42

Figure S318. Get High-res Image Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'MYOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0622 (Fisher's exact test), Q value = 0.39

Table S1871. Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MYOM1 MUTATED	2	4	3
MYOM1 WILD-TYPE	27	15	61

'MYOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.114 (Fisher's exact test), Q value = 0.51

Table S1872. Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MYOM1 MUTATED	4	1	4
MYOM1 WILD-TYPE	29	47	27

'MORC3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.942 (Fisher's exact test), Q value = 1

Table S1873. Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
MORC3 MUTATED	2	7	0	0	1
MORC3 WILD-TYPE	54	145	11	5	17

'MORC3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.323 (Fisher's exact test), Q value = 0.73

Table S1874. Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
MORC3 MUTATED	3	0	3
MORC3 WILD-TYPE	40	39	50

'MORC3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S1875. Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
MORC3 MUTATED	2	4	3
MORC3 WILD-TYPE	69	68	57

'MORC3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0567 (Fisher's exact test), Q value = 0.37

Table S1876. Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
MORC3 MUTATED	0	5	3	1
MORC3 WILD-TYPE	68	73	28	25

'MORC3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0383 (Fisher's exact test), Q value = 0.31

Table S1877. Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
MORC3 MUTATED	5	5	0
MORC3 WILD-TYPE	74	80	83

Figure S319. Get High-res Image Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'MORC3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 3e-04 (Fisher's exact test), Q value = 0.011

Table S1878. Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
MORC3 MUTATED	0	0	3	3	4	0	0
MORC3 WILD-TYPE	44	41	14	30	31	31	46

Figure S320. Get High-res Image Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MORC3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.195 (Fisher's exact test), Q value = 0.59

Table S1879. Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
MORC3 MUTATED	4	4	1
MORC3 WILD-TYPE	65	75	91

'MORC3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00537 (Fisher's exact test), Q value = 0.09

Table S1880. Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
MORC3 MUTATED	7	0	0	2
MORC3 WILD-TYPE	66	43	79	43

Figure S321. Get High-res Image Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'MORC3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 0.69

Table S1881. Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
MORC3 MUTATED	2	1	1
MORC3 WILD-TYPE	27	18	63

'MORC3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0625 (Fisher's exact test), Q value = 0.39

Table S1882. Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
MORC3 MUTATED	3	0	1
MORC3 WILD-TYPE	30	48	30

'CCDC82 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 0.77

Table S1883. Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
CCDC82 MUTATED	2	1	0	0
CCDC82 WILD-TYPE	10	17	11	10

'CCDC82 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.284 (Fisher's exact test), Q value = 0.7

Table S1884. Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
CCDC82 MUTATED	1	0	1	1	0
CCDC82 WILD-TYPE	11	10	6	6	15

'CCDC82 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.622 (Fisher's exact test), Q value = 0.94

Table S1885. Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CCDC82 MUTATED	1	10	0	0	1
CCDC82 WILD-TYPE	55	142	11	5	17

'CCDC82 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.656 (Fisher's exact test), Q value = 0.96

Table S1886. Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CCDC82 MUTATED	3	1	4
CCDC82 WILD-TYPE	40	38	49

'CCDC82 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.493 (Fisher's exact test), Q value = 0.85

Table S1887. Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CCDC82 MUTATED	4	6	2
CCDC82 WILD-TYPE	67	66	58

'CCDC82 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.182 (Fisher's exact test), Q value = 0.59

Table S1888. Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CCDC82 MUTATED	1	7	2	2
CCDC82 WILD-TYPE	67	71	29	24

'CCDC82 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 0.53

Table S1889. Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CCDC82 MUTATED	6	5	1
CCDC82 WILD-TYPE	73	80	82

'CCDC82 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00297 (Fisher's exact test), Q value = 0.061

Table S1890. Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CCDC82 MUTATED	1	0	1	6	3	1	0
CCDC82 WILD-TYPE	43	41	16	27	32	30	46

Figure S322. Get High-res Image Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CCDC82 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.685 (Fisher's exact test), Q value = 0.97

Table S1891. Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CCDC82 MUTATED	3	5	3
CCDC82 WILD-TYPE	66	74	89

'CCDC82 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0353 (Fisher's exact test), Q value = 0.3

Table S1892. Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CCDC82 MUTATED	8	1	1	1
CCDC82 WILD-TYPE	65	42	78	44

Figure S323. Get High-res Image Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'CCDC82 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.519 (Fisher's exact test), Q value = 0.87

Table S1893. Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CCDC82 MUTATED	1	2	3
CCDC82 WILD-TYPE	28	17	61

'CCDC82 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0444 (Fisher's exact test), Q value = 0.32

Table S1894. Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CCDC82 MUTATED	3	0	3
CCDC82 WILD-TYPE	30	48	28

Figure S324. Get High-res Image Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'B3GALT5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S1895. Gene #177: 'B3GALT5 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
B3GALT5 MUTATED	0	4	0	0	0
B3GALT5 WILD-TYPE	56	148	11	5	18

'B3GALT5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.271 (Fisher's exact test), Q value = 0.7

Table S1896. Gene #177: 'B3GALT5 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
B3GALT5 MUTATED	3	1	0
B3GALT5 WILD-TYPE	68	71	60

'B3GALT5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.121 (Fisher's exact test), Q value = 0.52

Table S1897. Gene #177: 'B3GALT5 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
B3GALT5 MUTATED	2	0	2	0
B3GALT5 WILD-TYPE	66	78	29	26

'B3GALT5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.548 (Fisher's exact test), Q value = 0.89

Table S1898. Gene #177: 'B3GALT5 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
B3GALT5 MUTATED	0	2	2
B3GALT5 WILD-TYPE	79	83	81

'B3GALT5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.421 (Fisher's exact test), Q value = 0.79

Table S1899. Gene #177: 'B3GALT5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
B3GALT5 MUTATED	0	0	0	1	2	0	1
B3GALT5 WILD-TYPE	44	41	17	32	33	31	45

'B3GALT5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1900. Gene #177: 'B3GALT5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
B3GALT5 MUTATED	1	1	2
B3GALT5 WILD-TYPE	68	78	90

'B3GALT5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.632 (Fisher's exact test), Q value = 0.95

Table S1901. Gene #177: 'B3GALT5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
B3GALT5 MUTATED	2	0	2	0
B3GALT5 WILD-TYPE	71	43	77	45

'NOC3L MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 0.97

Table S1902. Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
NOC3L MUTATED	1	2	0	0
NOC3L WILD-TYPE	11	16	11	10

'NOC3L MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 0.6

Table S1903. Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
NOC3L MUTATED	2	0	1	0	0
NOC3L WILD-TYPE	10	10	6	7	15

'NOC3L MUTATION STATUS' versus 'CN_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 0.57

Table S1904. Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
NOC3L MUTATED	0	9	0	0	2
NOC3L WILD-TYPE	56	143	11	5	16

'NOC3L MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.383 (Fisher's exact test), Q value = 0.77

Table S1905. Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
NOC3L MUTATED	1	0	3
NOC3L WILD-TYPE	42	39	50

'NOC3L MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.427 (Fisher's exact test), Q value = 0.79

Table S1906. Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
NOC3L MUTATED	4	5	1
NOC3L WILD-TYPE	67	67	59

'NOC3L MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.726 (Fisher's exact test), Q value = 0.99

Table S1907. Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
NOC3L MUTATED	4	5	1	0
NOC3L WILD-TYPE	64	73	30	26

'NOC3L MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.93 (Fisher's exact test), Q value = 1

Table S1908. Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
NOC3L MUTATED	4	4	3
NOC3L WILD-TYPE	75	81	80

'NOC3L MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00299 (Fisher's exact test), Q value = 0.061

Table S1909. Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
NOC3L MUTATED	0	0	0	5	4	0	2
NOC3L WILD-TYPE	44	41	17	28	31	31	44

Figure S325. Get High-res Image Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NOC3L MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S1910. Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
NOC3L MUTATED	2	4	4
NOC3L WILD-TYPE	67	75	88

'NOC3L MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S1911. Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
NOC3L MUTATED	4	1	4	1
NOC3L WILD-TYPE	69	42	75	44

'NOC3L MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.56 (Fisher's exact test), Q value = 0.89

Table S1912. Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
NOC3L MUTATED	0	1	2
NOC3L WILD-TYPE	29	18	62

'NOC3L MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0195 (Fisher's exact test), Q value = 0.21

Table S1913. Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
NOC3L MUTATED	0	0	3
NOC3L WILD-TYPE	33	48	28

Figure S326. Get High-res Image Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NSUN4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 0.7

Table S1914. Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
NSUN4 MUTATED	0	3	0	0
NSUN4 WILD-TYPE	12	15	11	10

'NSUN4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0531 (Fisher's exact test), Q value = 0.35

Table S1915. Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
NSUN4 MUTATED	3	0	0	0	0
NSUN4 WILD-TYPE	9	10	7	7	15

'NSUN4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.248 (Fisher's exact test), Q value = 0.67

Table S1916. Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
NSUN4 MUTATED	1	3	0	0	2
NSUN4 WILD-TYPE	55	149	11	5	16

'NSUN4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S1917. Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
NSUN4 MUTATED	1	0	2
NSUN4 WILD-TYPE	42	39	51

'NSUN4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.742 (Fisher's exact test), Q value = 1

Table S1918. Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
NSUN4 MUTATED	2	1	2
NSUN4 WILD-TYPE	69	71	58

'NSUN4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1919. Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
NSUN4 MUTATED	2	2	1	0
NSUN4 WILD-TYPE	66	76	30	26

'NSUN4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.29 (Fisher's exact test), Q value = 0.7

Table S1920. Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
NSUN4 MUTATED	4	1	1
NSUN4 WILD-TYPE	75	84	82

'NSUN4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0814 (Fisher's exact test), Q value = 0.43

Table S1921. Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
NSUN4 MUTATED	1	0	0	2	3	0	0
NSUN4 WILD-TYPE	43	41	17	31	32	31	46

'NSUN4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.63 (Fisher's exact test), Q value = 0.95

Table S1922. Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
NSUN4 MUTATED	2	2	1
NSUN4 WILD-TYPE	67	77	91

'NSUN4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.602 (Fisher's exact test), Q value = 0.92

Table S1923. Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
NSUN4 MUTATED	1	0	2	2
NSUN4 WILD-TYPE	72	43	77	43

'ASXL2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 0.77

Table S1924. Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ASXL2 MUTATED	2	1	0	0
ASXL2 WILD-TYPE	10	17	11	10

'ASXL2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.283 (Fisher's exact test), Q value = 0.7

Table S1925. Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ASXL2 MUTATED	1	0	1	1	0
ASXL2 WILD-TYPE	11	10	6	6	15

'ASXL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.418 (Fisher's exact test), Q value = 0.79

Table S1926. Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ASXL2 MUTATED	1	11	0	0	2
ASXL2 WILD-TYPE	55	141	11	5	16

'ASXL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.388 (Fisher's exact test), Q value = 0.77

Table S1927. Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ASXL2 MUTATED	2	1	5
ASXL2 WILD-TYPE	41	38	48

'ASXL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.188 (Fisher's exact test), Q value = 0.59

Table S1928. Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ASXL2 MUTATED	2	7	2
ASXL2 WILD-TYPE	69	65	58

'ASXL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.666 (Fisher's exact test), Q value = 0.97

Table S1929. Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ASXL2 MUTATED	2	6	2	1
ASXL2 WILD-TYPE	66	72	29	25

'ASXL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.275 (Fisher's exact test), Q value = 0.7

Table S1930. Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ASXL2 MUTATED	6	6	2
ASXL2 WILD-TYPE	73	79	81

'ASXL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00904 (Fisher's exact test), Q value = 0.13

Table S1931. Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ASXL2 MUTATED	1	1	1	6	4	1	0
ASXL2 WILD-TYPE	43	40	16	27	31	30	46

Figure S327. Get High-res Image Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ASXL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S1932. Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ASXL2 MUTATED	4	5	4
ASXL2 WILD-TYPE	65	74	88

'ASXL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.362 (Fisher's exact test), Q value = 0.77

Table S1933. Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ASXL2 MUTATED	7	2	3	1
ASXL2 WILD-TYPE	66	41	76	44

'ASXL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.516 (Fisher's exact test), Q value = 0.87

Table S1934. Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ASXL2 MUTATED	1	2	3
ASXL2 WILD-TYPE	28	17	61

'ASXL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0277 (Fisher's exact test), Q value = 0.26

Table S1935. Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ASXL2 MUTATED	2	0	4
ASXL2 WILD-TYPE	31	48	27

Figure S328. Get High-res Image Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CHD4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0978 (Fisher's exact test), Q value = 0.47

Table S1936. Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
CHD4 MUTATED	1	6	0	2
CHD4 WILD-TYPE	11	12	11	8

'CHD4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.338 (Fisher's exact test), Q value = 0.75

Table S1937. Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
CHD4 MUTATED	2	4	0	1	2
CHD4 WILD-TYPE	10	6	7	6	13

'CHD4 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1938. Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
CHD4 MUTATED	8	24	1	0	2
CHD4 WILD-TYPE	48	128	10	5	16

'CHD4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.744 (Fisher's exact test), Q value = 1

Table S1939. Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
CHD4 MUTATED	7	4	8
CHD4 WILD-TYPE	36	35	45

'CHD4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.848 (Fisher's exact test), Q value = 1

Table S1940. Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
CHD4 MUTATED	9	10	10
CHD4 WILD-TYPE	62	62	50

'CHD4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.629 (Fisher's exact test), Q value = 0.95

Table S1941. Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
CHD4 MUTATED	7	12	6	4
CHD4 WILD-TYPE	61	66	25	22

'CHD4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.363 (Fisher's exact test), Q value = 0.77

Table S1942. Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
CHD4 MUTATED	15	10	10
CHD4 WILD-TYPE	64	75	73

'CHD4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.333 (Fisher's exact test), Q value = 0.74

Table S1943. Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
CHD4 MUTATED	7	4	2	6	8	1	7
CHD4 WILD-TYPE	37	37	15	27	27	30	39

'CHD4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.548 (Fisher's exact test), Q value = 0.89

Table S1944. Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
CHD4 MUTATED	9	12	9
CHD4 WILD-TYPE	60	67	83

'CHD4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S1945. Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
CHD4 MUTATED	9	4	10	7
CHD4 WILD-TYPE	64	39	69	38

'CHD4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S1946. Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
CHD4 MUTATED	3	2	10
CHD4 WILD-TYPE	26	17	54

'CHD4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.73 (Fisher's exact test), Q value = 0.99

Table S1947. Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
CHD4 MUTATED	5	5	5
CHD4 WILD-TYPE	28	43	26

'FCN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.432 (Fisher's exact test), Q value = 0.79

Table S1948. Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
FCN1 MUTATED	0	6	0	0	1
FCN1 WILD-TYPE	56	146	11	5	17

'FCN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.557 (Fisher's exact test), Q value = 0.89

Table S1949. Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
FCN1 MUTATED	2	0	2
FCN1 WILD-TYPE	41	39	51

'FCN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1950. Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
FCN1 MUTATED	2	2	1
FCN1 WILD-TYPE	69	70	59

'FCN1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S1951. Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
FCN1 MUTATED	1	2	1	1
FCN1 WILD-TYPE	67	76	30	25

'FCN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 0.72

Table S1952. Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
FCN1 MUTATED	4	2	1
FCN1 WILD-TYPE	75	83	82

'FCN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.396 (Fisher's exact test), Q value = 0.77

Table S1953. Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
FCN1 MUTATED	0	1	1	2	2	0	1
FCN1 WILD-TYPE	44	40	16	31	33	31	45

'FCN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S1954. Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
FCN1 MUTATED	2	3	2
FCN1 WILD-TYPE	67	76	90

'FCN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.952 (Fisher's exact test), Q value = 1

Table S1955. Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
FCN1 MUTATED	3	1	2	1
FCN1 WILD-TYPE	70	42	77	44

'NIPA2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.417 (Fisher's exact test), Q value = 0.79

Table S1956. Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
NIPA2 MUTATED	0	8	0	0	0
NIPA2 WILD-TYPE	56	144	11	5	18

'NIPA2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.827 (Fisher's exact test), Q value = 1

Table S1957. Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
NIPA2 MUTATED	2	1	1
NIPA2 WILD-TYPE	41	38	52

'NIPA2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.283 (Fisher's exact test), Q value = 0.7

Table S1958. Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
NIPA2 MUTATED	3	3	0
NIPA2 WILD-TYPE	68	69	60

'NIPA2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.147 (Fisher's exact test), Q value = 0.55

Table S1959. Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
NIPA2 MUTATED	2	1	3	0
NIPA2 WILD-TYPE	66	77	28	26

'NIPA2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1960. Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
NIPA2 MUTATED	2	3	3
NIPA2 WILD-TYPE	77	82	80

'NIPA2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0404 (Fisher's exact test), Q value = 0.31

Table S1961. Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
NIPA2 MUTATED	0	1	2	1	1	3	0
NIPA2 WILD-TYPE	44	40	15	32	34	28	46

Figure S329. Get High-res Image Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NIPA2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S1962. Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
NIPA2 MUTATED	3	2	3
NIPA2 WILD-TYPE	66	77	89

'NIPA2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S1963. Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
NIPA2 MUTATED	3	1	2	2
NIPA2 WILD-TYPE	70	42	77	43

'NIPA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.391 (Fisher's exact test), Q value = 0.77

Table S1964. Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
NIPA2 MUTATED	1	1	1
NIPA2 WILD-TYPE	28	18	63

'NIPA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.468 (Fisher's exact test), Q value = 0.82

Table S1965. Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
NIPA2 MUTATED	2	1	0
NIPA2 WILD-TYPE	31	47	31

'C14ORF118 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 0.97

Table S1966. Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
C14ORF118 MUTATED	2	1	1	0
C14ORF118 WILD-TYPE	10	17	10	10

'C14ORF118 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.091 (Fisher's exact test), Q value = 0.46

Table S1967. Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
C14ORF118 MUTATED	1	0	2	1	0
C14ORF118 WILD-TYPE	11	10	5	6	15

'C14ORF118 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 0.51

Table S1968. Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
C14ORF118 MUTATED	0	13	0	0	0
C14ORF118 WILD-TYPE	56	139	11	5	18

'C14ORF118 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1969. Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
C14ORF118 MUTATED	2	2	3
C14ORF118 WILD-TYPE	41	37	50

'C14ORF118 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 0.97

Table S1970. Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
C14ORF118 MUTATED	4	5	2
C14ORF118 WILD-TYPE	67	67	58

'C14ORF118 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.252 (Fisher's exact test), Q value = 0.67

Table S1971. Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
C14ORF118 MUTATED	2	4	4	1
C14ORF118 WILD-TYPE	66	74	27	25

'C14ORF118 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S1972. Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
C14ORF118 MUTATED	5	4	4
C14ORF118 WILD-TYPE	74	81	79

'C14ORF118 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0851 (Fisher's exact test), Q value = 0.44

Table S1973. Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
C14ORF118 MUTATED	1	0	1	4	4	2	1
C14ORF118 WILD-TYPE	43	41	16	29	31	29	45

'C14ORF118 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.188 (Fisher's exact test), Q value = 0.59

Table S1974. Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
C14ORF118 MUTATED	2	7	3
C14ORF118 WILD-TYPE	67	72	89

'C14ORF118 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.542 (Fisher's exact test), Q value = 0.88

Table S1975. Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
C14ORF118 MUTATED	6	1	3	2
C14ORF118 WILD-TYPE	67	42	76	43

'C14ORF118 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.31 (Fisher's exact test), Q value = 0.72

Table S1976. Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
C14ORF118 MUTATED	2	2	2
C14ORF118 WILD-TYPE	27	17	62

'C14ORF118 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S1977. Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
C14ORF118 MUTATED	2	2	2
C14ORF118 WILD-TYPE	31	46	29

'THAP5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 0.57

Table S1978. Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
THAP5 MUTATED	0	4	0	0	2
THAP5 WILD-TYPE	56	148	11	5	16

'THAP5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0369 (Fisher's exact test), Q value = 0.3

Table S1979. Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
THAP5 MUTATED	0	0	4
THAP5 WILD-TYPE	43	39	49

Figure S330. Get High-res Image Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'THAP5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.86 (Fisher's exact test), Q value = 1

Table S1980. Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
THAP5 MUTATED	1	2	2
THAP5 WILD-TYPE	70	70	58

'THAP5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.733 (Fisher's exact test), Q value = 0.99

Table S1981. Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
THAP5 MUTATED	1	3	1	0
THAP5 WILD-TYPE	67	75	30	26

'THAP5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.29 (Fisher's exact test), Q value = 0.7

Table S1982. Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
THAP5 MUTATED	4	1	1
THAP5 WILD-TYPE	75	84	82

'THAP5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00536 (Fisher's exact test), Q value = 0.09

Table S1983. Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
THAP5 MUTATED	0	0	0	2	4	0	0
THAP5 WILD-TYPE	44	41	17	31	31	31	46

Figure S331. Get High-res Image Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'THAP5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1984. Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
THAP5 MUTATED	1	2	2
THAP5 WILD-TYPE	68	77	90

'THAP5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.869 (Fisher's exact test), Q value = 1

Table S1985. Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
THAP5 MUTATED	2	0	2	1
THAP5 WILD-TYPE	71	43	77	44

'ZNF611 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1986. Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
ZNF611 MUTATED	1	1	1	0
ZNF611 WILD-TYPE	11	17	10	10

'ZNF611 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0786 (Fisher's exact test), Q value = 0.43

Table S1987. Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
ZNF611 MUTATED	1	0	2	0	0
ZNF611 WILD-TYPE	11	10	5	7	15

'ZNF611 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.51 (Fisher's exact test), Q value = 0.86

Table S1988. Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF611 MUTATED	1	11	0	0	0
ZNF611 WILD-TYPE	55	141	11	5	18

'ZNF611 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.138 (Fisher's exact test), Q value = 0.54

Table S1989. Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF611 MUTATED	3	0	5
ZNF611 WILD-TYPE	40	39	48

'ZNF611 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S1990. Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF611 MUTATED	3	5	3
ZNF611 WILD-TYPE	68	67	57

'ZNF611 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0998 (Fisher's exact test), Q value = 0.48

Table S1991. Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF611 MUTATED	1	5	4	1
ZNF611 WILD-TYPE	67	73	27	25

'ZNF611 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 0.82

Table S1992. Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF611 MUTATED	5	5	2
ZNF611 WILD-TYPE	74	80	81

'ZNF611 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.003 (Fisher's exact test), Q value = 0.061

Table S1993. Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF611 MUTATED	1	0	1	6	3	1	0
ZNF611 WILD-TYPE	43	41	16	27	32	30	46

Figure S332. Get High-res Image Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF611 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.189 (Fisher's exact test), Q value = 0.59

Table S1994. Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF611 MUTATED	2	7	3
ZNF611 WILD-TYPE	67	72	89

'ZNF611 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0125 (Fisher's exact test), Q value = 0.17

Table S1995. Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF611 MUTATED	9	1	1	1
ZNF611 WILD-TYPE	64	42	78	44

Figure S333. Get High-res Image Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'ZNF611 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.17 (Fisher's exact test), Q value = 0.58

Table S1996. Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
ZNF611 MUTATED	0	2	3
ZNF611 WILD-TYPE	29	17	61

'ZNF611 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.011 (Fisher's exact test), Q value = 0.16

Table S1997. Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
ZNF611 MUTATED	1	0	4
ZNF611 WILD-TYPE	32	48	27

Figure S334. Get High-res Image Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ZCCHC18 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 0.88

Table S1998. Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZCCHC18 MUTATED	0	6	0	0	0
ZCCHC18 WILD-TYPE	56	146	11	5	18

'ZCCHC18 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 0.51

Table S1999. Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZCCHC18 MUTATED	0	0	3
ZCCHC18 WILD-TYPE	43	39	50

'ZCCHC18 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.595 (Fisher's exact test), Q value = 0.92

Table S2000. Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZCCHC18 MUTATED	3	1	2
ZCCHC18 WILD-TYPE	68	71	58

'ZCCHC18 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.107 (Fisher's exact test), Q value = 0.5

Table S2001. Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZCCHC18 MUTATED	1	1	3	1
ZCCHC18 WILD-TYPE	67	77	28	25

'ZCCHC18 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 0.53

Table S2002. Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZCCHC18 MUTATED	2	4	0
ZCCHC18 WILD-TYPE	77	81	83

'ZCCHC18 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00517 (Fisher's exact test), Q value = 0.089

Table S2003. Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZCCHC18 MUTATED	0	0	0	2	4	0	0
ZCCHC18 WILD-TYPE	44	41	17	31	31	31	46

Figure S335. Get High-res Image Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZCCHC18 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.525 (Fisher's exact test), Q value = 0.87

Table S2004. Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZCCHC18 MUTATED	1	3	1
ZCCHC18 WILD-TYPE	68	76	91

'ZCCHC18 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0846 (Fisher's exact test), Q value = 0.44

Table S2005. Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZCCHC18 MUTATED	4	0	0	1
ZCCHC18 WILD-TYPE	69	43	79	44

'PRKCE MUTATION STATUS' versus 'CN_CNMF'

P value = 0.192 (Fisher's exact test), Q value = 0.59

Table S2006. Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PRKCE MUTATED	0	7	0	0	2
PRKCE WILD-TYPE	56	145	11	5	16

'PRKCE MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S2007. Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PRKCE MUTATED	2	1	3
PRKCE WILD-TYPE	41	38	50

'PRKCE MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S2008. Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PRKCE MUTATED	3	3	2
PRKCE WILD-TYPE	68	69	58

'PRKCE MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.522 (Fisher's exact test), Q value = 0.87

Table S2009. Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PRKCE MUTATED	1	4	2	1
PRKCE WILD-TYPE	67	74	29	25

'PRKCE MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.2 (Fisher's exact test), Q value = 0.6

Table S2010. Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PRKCE MUTATED	5	3	1
PRKCE WILD-TYPE	74	82	82

'PRKCE MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0151 (Fisher's exact test), Q value = 0.19

Table S2011. Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PRKCE MUTATED	0	0	1	3	4	0	1
PRKCE WILD-TYPE	44	41	16	30	31	31	45

Figure S336. Get High-res Image Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PRKCE MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S2012. Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PRKCE MUTATED	2	4	3
PRKCE WILD-TYPE	67	75	89

'PRKCE MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.135 (Fisher's exact test), Q value = 0.53

Table S2013. Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PRKCE MUTATED	6	0	2	1
PRKCE WILD-TYPE	67	43	77	44

'PRKCE MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 0.53

Table S2014. Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
PRKCE MUTATED	0	2	1
PRKCE WILD-TYPE	29	17	63

'PRKCE MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S2015. Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
PRKCE MUTATED	1	1	1
PRKCE WILD-TYPE	32	47	30

'BMP2K MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.135 (Fisher's exact test), Q value = 0.53

Table S2016. Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
BMP2K MUTATED	3	1	0	0
BMP2K WILD-TYPE	9	17	11	10

'BMP2K MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0911 (Fisher's exact test), Q value = 0.46

Table S2017. Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
BMP2K MUTATED	1	0	1	2	0
BMP2K WILD-TYPE	11	10	6	5	15

'BMP2K MUTATION STATUS' versus 'CN_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 0.58

Table S2018. Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
BMP2K MUTATED	0	12	0	0	1
BMP2K WILD-TYPE	56	140	11	5	17

'BMP2K MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.262 (Fisher's exact test), Q value = 0.69

Table S2019. Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
BMP2K MUTATED	1	1	5
BMP2K WILD-TYPE	42	38	48

'BMP2K MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.631 (Fisher's exact test), Q value = 0.95

Table S2020. Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
BMP2K MUTATED	5	4	2
BMP2K WILD-TYPE	66	68	58

'BMP2K MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.912 (Fisher's exact test), Q value = 1

Table S2021. Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
BMP2K MUTATED	5	4	1	1
BMP2K WILD-TYPE	63	74	30	25

'BMP2K MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.271 (Fisher's exact test), Q value = 0.7

Table S2022. Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
BMP2K MUTATED	2	7	4
BMP2K WILD-TYPE	77	78	79

'BMP2K MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0151 (Fisher's exact test), Q value = 0.19

Table S2023. Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
BMP2K MUTATED	0	1	1	6	3	1	1
BMP2K WILD-TYPE	44	40	16	27	32	30	45

Figure S337. Get High-res Image Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'BMP2K MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.212 (Fisher's exact test), Q value = 0.61

Table S2024. Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
BMP2K MUTATED	1	6	6
BMP2K WILD-TYPE	68	73	86

'BMP2K MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.344 (Fisher's exact test), Q value = 0.76

Table S2025. Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
BMP2K MUTATED	7	1	4	1
BMP2K WILD-TYPE	66	42	75	44

'BMP2K MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S2026. Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
BMP2K MUTATED	1	1	4
BMP2K WILD-TYPE	28	18	60

'BMP2K MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.766 (Fisher's exact test), Q value = 1

Table S2027. Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
BMP2K MUTATED	1	3	2
BMP2K WILD-TYPE	32	45	29

'PRPF38B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.274 (Fisher's exact test), Q value = 0.7

Table S2028. Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
PRPF38B MUTATED	0	10	0	0	1
PRPF38B WILD-TYPE	56	142	11	5	17

'PRPF38B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.106 (Fisher's exact test), Q value = 0.5

Table S2029. Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
PRPF38B MUTATED	1	0	5
PRPF38B WILD-TYPE	42	39	48

'PRPF38B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 0.97

Table S2030. Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
PRPF38B MUTATED	4	5	2
PRPF38B WILD-TYPE	67	67	58

'PRPF38B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S2031. Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
PRPF38B MUTATED	4	4	2	1
PRPF38B WILD-TYPE	64	74	29	25

'PRPF38B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.169 (Fisher's exact test), Q value = 0.58

Table S2032. Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
PRPF38B MUTATED	4	6	1
PRPF38B WILD-TYPE	75	79	82

'PRPF38B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00042 (Fisher's exact test), Q value = 0.015

Table S2033. Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
PRPF38B MUTATED	0	1	0	5	5	0	0
PRPF38B WILD-TYPE	44	40	17	28	30	31	46

Figure S338. Get High-res Image Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PRPF38B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 0.63

Table S2034. Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
PRPF38B MUTATED	1	6	4
PRPF38B WILD-TYPE	68	73	88

'PRPF38B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.214 (Fisher's exact test), Q value = 0.62

Table S2035. Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
PRPF38B MUTATED	6	2	1	2
PRPF38B WILD-TYPE	67	41	78	43

'PRPF38B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 0.77

Table S2036. Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
PRPF38B MUTATED	1	1	1
PRPF38B WILD-TYPE	28	18	63

'PRPF38B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.112 (Fisher's exact test), Q value = 0.51

Table S2037. Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
PRPF38B MUTATED	1	0	2
PRPF38B WILD-TYPE	32	48	29

'LGMN MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.383 (Fisher's exact test), Q value = 0.77

Table S2038. Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
LGMN MUTATED	2	1	0	0
LGMN WILD-TYPE	10	17	11	10

'LGMN MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0793 (Fisher's exact test), Q value = 0.43

Table S2039. Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
LGMN MUTATED	1	0	2	0	0
LGMN WILD-TYPE	11	10	5	7	15

'LGMN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.43 (Fisher's exact test), Q value = 0.79

Table S2040. Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
LGMN MUTATED	0	6	0	0	1
LGMN WILD-TYPE	56	146	11	5	17

'LGMN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.712 (Fisher's exact test), Q value = 0.98

Table S2041. Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
LGMN MUTATED	3	3	1
LGMN WILD-TYPE	68	69	59

'LGMN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S2042. Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
LGMN MUTATED	2	3	1	1
LGMN WILD-TYPE	66	75	30	25

'LGMN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 0.55

Table S2043. Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
LGMN MUTATED	3	4	0
LGMN WILD-TYPE	76	81	83

'LGMN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00116 (Fisher's exact test), Q value = 0.032

Table S2044. Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
LGMN MUTATED	0	0	1	0	5	1	0
LGMN WILD-TYPE	44	41	16	33	30	30	46

Figure S339. Get High-res Image Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'LGMN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S2045. Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
LGMN MUTATED	2	2	2
LGMN WILD-TYPE	67	77	90

'LGMN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.134 (Fisher's exact test), Q value = 0.53

Table S2046. Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
LGMN MUTATED	4	1	0	1
LGMN WILD-TYPE	69	42	79	44

'SSH2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 0.97

Table S2047. Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
SSH2 MUTATED	2	1	1	0
SSH2 WILD-TYPE	10	17	10	10

'SSH2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0915 (Fisher's exact test), Q value = 0.46

Table S2048. Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
SSH2 MUTATED	1	0	2	1	0
SSH2 WILD-TYPE	11	10	5	6	15

'SSH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.145 (Fisher's exact test), Q value = 0.55

Table S2049. Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
SSH2 MUTATED	0	12	0	0	0
SSH2 WILD-TYPE	56	140	11	5	18

'SSH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S2050. Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
SSH2 MUTATED	2	1	1
SSH2 WILD-TYPE	41	38	52

'SSH2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.24 (Fisher's exact test), Q value = 0.66

Table S2051. Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
SSH2 MUTATED	6	4	1
SSH2 WILD-TYPE	65	68	59

'SSH2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.318 (Fisher's exact test), Q value = 0.73

Table S2052. Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
SSH2 MUTATED	5	3	3	0
SSH2 WILD-TYPE	63	75	28	26

'SSH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.932 (Fisher's exact test), Q value = 1

Table S2053. Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
SSH2 MUTATED	3	5	4
SSH2 WILD-TYPE	76	80	79

'SSH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.344 (Fisher's exact test), Q value = 0.76

Table S2054. Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
SSH2 MUTATED	0	2	2	3	2	1	2
SSH2 WILD-TYPE	44	39	15	30	33	30	44

'SSH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S2055. Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
SSH2 MUTATED	3	4	4
SSH2 WILD-TYPE	66	75	88

'SSH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.717 (Fisher's exact test), Q value = 0.98

Table S2056. Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
SSH2 MUTATED	5	2	3	1
SSH2 WILD-TYPE	68	41	76	44

'SSH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.804 (Fisher's exact test), Q value = 1

Table S2057. Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
SSH2 MUTATED	1	1	2
SSH2 WILD-TYPE	28	18	62

'SSH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.814 (Fisher's exact test), Q value = 1

Table S2058. Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
SSH2 MUTATED	2	1	1
SSH2 WILD-TYPE	31	47	30

'EMR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.178 (Fisher's exact test), Q value = 0.59

Table S2059. Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
EMR1 MUTATED	0	11	0	0	0
EMR1 WILD-TYPE	56	141	11	5	18

'EMR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 0.7

Table S2060. Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
EMR1 MUTATED	2	0	4
EMR1 WILD-TYPE	41	39	49

'EMR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 0.69

Table S2061. Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
EMR1 MUTATED	4	6	1
EMR1 WILD-TYPE	67	66	59

'EMR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.536 (Fisher's exact test), Q value = 0.88

Table S2062. Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
EMR1 MUTATED	2	5	3	1
EMR1 WILD-TYPE	66	73	28	25

'EMR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.37 (Fisher's exact test), Q value = 0.77

Table S2063. Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
EMR1 MUTATED	3	6	2
EMR1 WILD-TYPE	76	79	81

'EMR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00113 (Fisher's exact test), Q value = 0.031

Table S2064. Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
EMR1 MUTATED	0	0	1	6	3	0	1
EMR1 WILD-TYPE	44	41	16	27	32	31	45

Figure S340. Get High-res Image Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'EMR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.798 (Fisher's exact test), Q value = 1

Table S2065. Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
EMR1 MUTATED	2	4	5
EMR1 WILD-TYPE	67	75	87

'EMR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.166 (Fisher's exact test), Q value = 0.58

Table S2066. Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
EMR1 MUTATED	7	1	2	1
EMR1 WILD-TYPE	66	42	77	44

'EMR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 0.59

Table S2067. Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
EMR1 MUTATED	0	2	2
EMR1 WILD-TYPE	29	17	62

'EMR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0355 (Fisher's exact test), Q value = 0.3

Table S2068. Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
EMR1 MUTATED	1	0	3
EMR1 WILD-TYPE	32	48	28

Figure S341. Get High-res Image Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'OR5AK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 0.53

Table S2069. Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
OR5AK2 MUTATED	0	3	0	0	2
OR5AK2 WILD-TYPE	56	149	11	5	16

'OR5AK2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S2070. Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
OR5AK2 MUTATED	1	2	1
OR5AK2 WILD-TYPE	70	70	59

'OR5AK2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.319 (Fisher's exact test), Q value = 0.73

Table S2071. Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
OR5AK2 MUTATED	0	3	1	0
OR5AK2 WILD-TYPE	68	75	30	26

'OR5AK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 0.7

Table S2072. Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
OR5AK2 MUTATED	2	3	0
OR5AK2 WILD-TYPE	77	82	83

'OR5AK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0199 (Fisher's exact test), Q value = 0.21

Table S2073. Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
OR5AK2 MUTATED	0	0	0	2	3	0	0
OR5AK2 WILD-TYPE	44	41	17	31	32	31	46

Figure S342. Get High-res Image Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'OR5AK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 0.53

Table S2074. Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
OR5AK2 MUTATED	2	3	0
OR5AK2 WILD-TYPE	67	76	92

'OR5AK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.53 (Fisher's exact test), Q value = 0.88

Table S2075. Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
OR5AK2 MUTATED	3	1	1	0
OR5AK2 WILD-TYPE	70	42	78	45

'C1ORF101 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.63 (Fisher's exact test), Q value = 0.95

Table S2076. Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	18	11	10
C1ORF101 MUTATED	1	1	2	0
C1ORF101 WILD-TYPE	11	17	9	10

'C1ORF101 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.322 (Fisher's exact test), Q value = 0.73

Table S2077. Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	12	10	7	7	15
C1ORF101 MUTATED	1	0	2	0	1
C1ORF101 WILD-TYPE	11	10	5	7	14

'C1ORF101 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.145 (Fisher's exact test), Q value = 0.55

Table S2078. Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
C1ORF101 MUTATED	0	10	0	0	2
C1ORF101 WILD-TYPE	56	142	11	5	16

'C1ORF101 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S2079. Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
C1ORF101 MUTATED	2	1	1
C1ORF101 WILD-TYPE	41	38	52

'C1ORF101 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S2080. Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
C1ORF101 MUTATED	3	3	3
C1ORF101 WILD-TYPE	68	69	57

'C1ORF101 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S2081. Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
C1ORF101 MUTATED	3	4	1	1
C1ORF101 WILD-TYPE	65	74	30	25

'C1ORF101 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.497 (Fisher's exact test), Q value = 0.85

Table S2082. Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
C1ORF101 MUTATED	6	3	3
C1ORF101 WILD-TYPE	73	82	80

'C1ORF101 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.705 (Fisher's exact test), Q value = 0.98

Table S2083. Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
C1ORF101 MUTATED	1	1	1	3	3	1	2
C1ORF101 WILD-TYPE	43	40	16	30	32	30	44

'C1ORF101 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.244 (Fisher's exact test), Q value = 0.66

Table S2084. Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
C1ORF101 MUTATED	3	6	2
C1ORF101 WILD-TYPE	66	73	90

'C1ORF101 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.972 (Fisher's exact test), Q value = 1

Table S2085. Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
C1ORF101 MUTATED	4	2	3	2
C1ORF101 WILD-TYPE	69	41	76	43

'C1ORF101 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0419 (Fisher's exact test), Q value = 0.32

Table S2086. Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	29	19	64
C1ORF101 MUTATED	1	2	0
C1ORF101 WILD-TYPE	28	17	64

Figure S343. Get High-res Image Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'C1ORF101 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.183 (Fisher's exact test), Q value = 0.59

Table S2087. Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	33	48	31
C1ORF101 MUTATED	2	0	1
C1ORF101 WILD-TYPE	31	48	30

'ZNF534 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.192 (Fisher's exact test), Q value = 0.59

Table S2088. Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
ZNF534 MUTATED	0	7	0	0	2
ZNF534 WILD-TYPE	56	145	11	5	16

'ZNF534 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0377 (Fisher's exact test), Q value = 0.31

Table S2089. Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	43	39	53
ZNF534 MUTATED	0	0	4
ZNF534 WILD-TYPE	43	39	49

Figure S344. Get High-res Image Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'ZNF534 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.566 (Fisher's exact test), Q value = 0.89

Table S2090. Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
ZNF534 MUTATED	4	2	1
ZNF534 WILD-TYPE	67	70	59

'ZNF534 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S2091. Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
ZNF534 MUTATED	2	3	1	1
ZNF534 WILD-TYPE	66	75	30	25

'ZNF534 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.249 (Fisher's exact test), Q value = 0.67

Table S2092. Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
ZNF534 MUTATED	3	5	1
ZNF534 WILD-TYPE	76	80	82

'ZNF534 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00028 (Fisher's exact test), Q value = 0.011

Table S2093. Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
ZNF534 MUTATED	0	0	0	4	5	0	0
ZNF534 WILD-TYPE	44	41	17	29	30	31	46

Figure S345. Get High-res Image Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF534 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S2094. Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
ZNF534 MUTATED	2	2	4
ZNF534 WILD-TYPE	67	77	88

'ZNF534 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.515 (Fisher's exact test), Q value = 0.87

Table S2095. Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
ZNF534 MUTATED	4	1	3	0
ZNF534 WILD-TYPE	69	42	76	45

'FAM122A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.534 (Fisher's exact test), Q value = 0.88

Table S2096. Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	56	152	11	5	18
FAM122A MUTATED	0	6	0	0	0
FAM122A WILD-TYPE	56	146	11	5	18

'FAM122A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S2097. Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	71	72	60
FAM122A MUTATED	2	2	2
FAM122A WILD-TYPE	69	70	58

'FAM122A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.175 (Fisher's exact test), Q value = 0.58

Table S2098. Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	68	78	31	26
FAM122A MUTATED	1	2	3	0
FAM122A WILD-TYPE	67	76	28	26

'FAM122A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 0.63

Table S2099. Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	79	85	83
FAM122A MUTATED	3	3	0
FAM122A WILD-TYPE	76	82	83

'FAM122A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0051 (Fisher's exact test), Q value = 0.089

Table S2100. Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	44	41	17	33	35	31	46
FAM122A MUTATED	0	0	1	0	4	1	0
FAM122A WILD-TYPE	44	41	16	33	31	30	46

Figure S346. Get High-res Image Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FAM122A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.632 (Fisher's exact test), Q value = 0.95

Table S2101. Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	69	79	92
FAM122A MUTATED	2	2	1
FAM122A WILD-TYPE	67	77	91

'FAM122A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0853 (Fisher's exact test), Q value = 0.44

Table S2102. Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	73	43	79	45
FAM122A MUTATED	4	0	0	1
FAM122A WILD-TYPE	69	43	79	44

Methods & Data

Input

Mutation data file = sample_sig_gene_table.txt from Mutsig_2CV pipeline
Processed Mutation data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/UCEC-TP/20217348/transformed.cor.cli.txt
Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/UCEC-TP/20144021/UCEC-TP.transferedmergedcluster.txt
Number of patients = 248
Number of significantly mutated genes = 197
Number of Molecular subtypes = 12
Exclude genes that fewer than K tumors have mutations, K = 3

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

Download Results

In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.

References

[1] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)

[2] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)

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