Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q TP53 51 (89%) 6 0.5685 0.941 0.63057 0.97 0.74622 0.981 0.13755 0.595 0.87682 1 0.51343 0.911 1 1 0.91273 1 1 1 1 1 FBXW7 22 (39%) 35 0.26199 0.758 0.72206 0.97 0.14957 0.595 0.16837 0.617 0.63133 0.97 0.10279 0.497 0.47338 0.897 0.93154 1 1 1 0.77557 0.981 PPP2R1A 16 (28%) 41 0.75982 0.981 0.70538 0.97 0.69536 0.97 0.49938 0.911 0.59149 0.957 0.672 0.97 0.57147 0.941 0.31712 0.774 0.6993 0.97 0.23476 0.698 KRAS 7 (12%) 50 0.10184 0.497 0.01426 0.261 0.42262 0.837 0.20056 0.644 0.03182 0.435 0.0062399 0.172 0.46389 0.895 0.091689 0.497 0.31101 0.774 0.058019 0.497 PTEN 11 (19%) 46 0.093639 0.497 8.9999e-05 0.0099 0.33266 0.774 0.01881 0.296 0.00188 0.103 0.04515 0.497 0.096359 0.497 0.061439 0.497 0.004 0.147 0.01341 0.261 RB1 6 (11%) 51 0.2254 0.689 0.093249 0.497 0.61968 0.97 0.31302 0.774 0.079979 0.497 0.099219 0.497 0.8347 1 0.86131 1 0.86501 1 1 1 ZBTB7B 6 (11%) 51 0.72285 0.97 0.93905 1 0.30469 0.774 0.37803 0.785 1 1 0.9147 1 0.098699 0.497 0.14728 0.595 0.48106 0.897 0.1634 0.617 PIK3R1 6 (11%) 51 1 1 0.93881 1 0.57286 0.941 0.77464 0.981 0.54398 0.941 0.70405 0.97 0.42602 0.837 0.50584 0.911 1 1 0.30462 0.774 ARHGAP35 6 (11%) 51 0.56821 0.941 0.33066 0.774 0.69518 0.97 0.34473 0.774 1 1 0.40135 0.818 1 1 0.19096 0.644 1 1 0.17729 0.629 PIK3CA 20 (35%) 37 0.63659 0.97 0.90214 1 0.20489 0.644 0.29402 0.774 0.36428 0.777 0.36731 0.777 0.11039 0.506 0.3394 0.774 0.19308 0.644 0.2707 0.764 MAMLD1 4 (7%) 53 1 1 0.90295 1 0.10384 0.497 0.03563 0.435 0.68317 0.97 0.76898 0.981 0.065579 0.497 0.67642 0.97 0.15155 0.595 0.35952 0.777