Clinical Features CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1q gain 8 (10%) 72 0.71487 0.926 0.71441 0.926 0.70128 0.922 0.80241 0.933 0.21076 0.502 0.057539 0.245 1 1 0.03778 0.188 2p gain 10 (12%) 70 0.31704 0.593 1 1 0.03772 0.188 0.11447 0.374 0.10837 0.366 0.85013 0.958 0.55267 0.814 0.03127 0.173 2q gain 8 (10%) 72 0.39407 0.664 0.71463 0.926 0.054889 0.24 0.11223 0.369 0.27829 0.543 0.195 0.476 0.34583 0.619 0.0069999 0.056 4p gain 7 (9%) 73 0.0278 0.164 0.2817 0.543 0.1543 0.431 0.12132 0.384 0.88397 0.985 0.36781 0.639 0.8731 0.976 0.2297 0.504 4q gain 4 (5%) 76 0.15744 0.431 0.26706 0.543 0.3971 0.667 0.34469 0.619 0.42499 0.695 0.82449 0.948 1 1 0.22645 0.504 5p gain 3 (4%) 77 0.16095 0.431 0.44117 0.695 0.7844 0.933 0.10684 0.366 0.79261 0.933 0.27874 0.543 1 1 0.21579 0.502 5q gain 3 (4%) 77 0.15964 0.431 0.43917 0.695 0.78406 0.933 0.1072 0.366 0.79662 0.933 0.27452 0.543 1 1 0.21524 0.502 6p gain 39 (49%) 41 0.00018 0.00245 0.00425 0.0364 2e-04 0.00255 3e-04 0.0036 3e-05 0.00049 9.9999e-06 0.000185 0.01023 0.0759 3e-05 0.00049 6q gain 16 (20%) 64 0.0060899 0.0497 0.0024 0.0239 0.00029 0.00359 0.00098999 0.0109 0.00019 0.0025 0.00033 0.00385 0.00349 0.0316 0.00011 0.00155 7p gain 9 (11%) 71 0.16494 0.431 0.13064 0.401 1 1 0.73961 0.933 0.66059 0.889 0.1786 0.447 0.64145 0.872 0.78173 0.933 7q gain 8 (10%) 72 0.055239 0.24 0.03128 0.173 0.89043 0.989 0.44791 0.699 0.31517 0.593 0.32845 0.604 0.26122 0.543 0.67171 0.899 8p gain 33 (41%) 47 0.00134 0.0144 0.00084999 0.00963 0.00283 0.0269 0.00381 0.0338 0.01976 0.126 0.01442 0.0997 0.03801 0.188 0.01399 0.0984 8q gain 53 (66%) 27 9.9999e-06 0.000185 9.9999e-06 0.000185 3e-05 0.00049 9.9999e-06 0.000185 0.00011 0.00155 9.9999e-06 0.000185 9.9999e-06 0.000185 9.9999e-05 0.00151 9p gain 6 (8%) 74 0.23256 0.507 0.17861 0.447 0.40133 0.671 0.64321 0.872 0.74841 0.933 1 1 0.12483 0.389 0.91899 1 9q gain 5 (6%) 75 0.5088 0.763 0.03719 0.188 0.83767 0.951 0.83945 0.951 0.35097 0.621 0.75234 0.933 0.01856 0.123 0.75779 0.933 11p gain 9 (11%) 71 0.16288 0.431 0.54007 0.798 1 1 0.73759 0.933 0.2514 0.534 0.23538 0.508 1 1 0.70555 0.923 11q gain 10 (12%) 70 0.3171 0.593 0.82994 0.948 0.90927 0.999 0.82888 0.948 0.13526 0.406 0.11708 0.379 1 1 0.70096 0.922 12p gain 3 (4%) 77 0.16156 0.431 0.44071 0.695 0.089919 0.343 0.0101 0.0759 0.79814 0.933 0.27783 0.543 1 1 0.27948 0.543 12q gain 3 (4%) 77 0.16083 0.431 0.44067 0.695 0.087939 0.343 0.0095499 0.0735 0.79441 0.933 0.27249 0.543 1 1 0.28196 0.543 13q gain 6 (8%) 74 0.10509 0.366 1 1 0.73522 0.933 0.75191 0.933 0.48842 0.739 0.5171 0.77 0.40792 0.677 0.11932 0.381 14q gain 3 (4%) 77 0.03735 0.188 0.43803 0.695 0.59159 0.833 0.32658 0.603 0.7971 0.933 0.59642 0.833 1 1 0.76528 0.933 16p gain 4 (5%) 76 1 1 0.43553 0.695 1 1 0.43815 0.695 0.33867 0.617 0.47181 0.726 0.83118 0.948 1 1 17p gain 8 (10%) 72 0.081569 0.326 0.80296 0.933 0.3929 0.664 0.21889 0.502 0.35209 0.621 0.058239 0.245 0.48146 0.736 0.70249 0.922 17q gain 9 (11%) 71 0.21817 0.502 1 1 0.42035 0.692 0.31379 0.593 0.25307 0.535 0.02916 0.17 0.26382 0.543 0.63224 0.866 20p gain 8 (10%) 72 0.0091999 0.0722 0.56704 0.832 0.38974 0.663 0.21912 0.502 0.27761 0.543 0.23937 0.514 0.79118 0.933 0.84404 0.954 20q gain 9 (11%) 71 0.00172 0.018 0.54014 0.798 0.14414 0.424 0.058129 0.245 0.18234 0.454 0.15875 0.431 0.90451 0.997 0.7801 0.933 21q gain 14 (18%) 66 0.00283 0.0269 0.19882 0.483 0.10354 0.366 0.01372 0.0982 0.86724 0.975 0.29601 0.567 0.12578 0.389 0.46396 0.717 22q gain 6 (8%) 74 0.10506 0.366 0.64093 0.872 0.15026 0.431 0.2185 0.502 0.49248 0.741 0.17529 0.444 1 1 0.11953 0.381 xp gain 10 (12%) 70 0.38764 0.662 0.090689 0.343 0.11076 0.367 0.14045 0.418 0.33725 0.617 0.37464 0.647 0.37581 0.647 0.26499 0.543 xq gain 9 (11%) 71 0.65952 0.889 0.28232 0.543 0.02386 0.143 0.02027 0.127 0.10562 0.366 0.10284 0.366 0.43352 0.695 0.087629 0.343 1p loss 19 (24%) 61 0.00428 0.0364 0.051819 0.23 0.78323 0.933 0.66234 0.889 0.36621 0.639 0.27777 0.543 0.26453 0.543 0.076249 0.311 1q loss 3 (4%) 77 0.03809 0.188 0.17021 0.434 0.21776 0.502 0.32216 0.598 0.42998 0.695 0.04687 0.217 0.089319 0.343 0.03143 0.173 3p loss 43 (54%) 37 9.9999e-06 0.000185 9.9999e-06 0.000185 9.9999e-06 0.000185 9.9999e-06 0.000185 9.9999e-06 0.000185 9.9999e-06 0.000185 9.9999e-06 0.000185 9.9999e-06 0.000185 3q loss 43 (54%) 37 9.9999e-06 0.000185 9.9999e-06 0.000185 9.9999e-06 0.000185 9.9999e-06 0.000185 9.9999e-06 0.000185 9.9999e-06 0.000185 9.9999e-06 0.000185 9.9999e-06 0.000185 4q loss 3 (4%) 77 1 1 0.78968 0.933 0.58891 0.833 0.60041 0.833 0.79657 0.933 0.27405 0.543 0.40736 0.677 0.48937 0.739 5q loss 3 (4%) 77 0.4491 0.699 0.10935 0.366 0.090109 0.343 0.169 0.434 0.59573 0.833 0.87217 0.976 0.29791 0.568 0.89409 0.989 6q loss 17 (21%) 63 6.9999e-05 0.0011 0.00343 0.0316 0.04848 0.22 0.00457 0.0381 0.10006 0.366 0.2281 0.504 0.03942 0.191 0.00196 0.02 8p loss 9 (11%) 71 0.02999 0.172 0.34517 0.619 0.03763 0.188 0.02287 0.139 0.22819 0.504 0.28155 0.543 0.16114 0.431 0.01861 0.123 8q loss 3 (4%) 77 0.78781 0.933 0.60283 0.833 1 1 0.79101 0.933 1 1 0.77334 0.933 0.7865 0.933 0.89341 0.989 9p loss 8 (10%) 72 0.10861 0.366 0.04046 0.194 0.34815 0.62 0.15426 0.431 0.1859 0.457 0.35321 0.621 0.17007 0.434 0.79237 0.933 9q loss 7 (9%) 73 0.16394 0.431 0.074029 0.305 0.59187 0.833 0.24255 0.518 0.095159 0.354 0.58354 0.833 0.078769 0.318 0.41808 0.691 11p loss 3 (4%) 77 0.03818 0.188 0.23512 0.508 0.04412 0.209 0.10815 0.366 0.22958 0.504 0.15199 0.431 0.21418 0.502 0.18424 0.456 12p loss 3 (4%) 77 0.78736 0.933 0.6067 0.833 1 1 0.7915 0.933 1 1 0.51595 0.77 0.5915 0.833 1 1 13q loss 3 (4%) 77 1 1 0.1692 0.434 0.59215 0.833 0.60326 0.833 1 1 1 1 0.78598 0.933 0.48743 0.739 15q loss 4 (5%) 76 0.15813 0.431 0.04997 0.224 0.83187 0.948 0.8238 0.948 1 1 0.91099 0.999 1 1 0.69579 0.922 16p loss 3 (4%) 77 1 1 0.44073 0.695 0.59006 0.833 0.60152 0.833 1 1 1 1 0.78522 0.933 0.35465 0.621 16q loss 16 (20%) 64 0.02127 0.131 0.13224 0.403 0.095519 0.354 0.01323 0.0964 0.82318 0.948 0.12509 0.389 0.14429 0.424 0.04774 0.219 19p loss 3 (4%) 77 0.45147 0.7 0.60482 0.833 0.78339 0.933 1 1 0.59583 0.833 0.2288 0.504 0.78477 0.933 0.69157 0.919 19q loss 3 (4%) 77 0.44891 0.699 0.60394 0.833 0.78114 0.933 1 1 0.59958 0.833 0.22811 0.504 0.78615 0.933 0.69152 0.919 xp loss 12 (15%) 68 0.34 0.617 0.0376 0.188 0.32265 0.598 0.26356 0.543 0.48114 0.736 0.57918 0.833 0.069999 0.291 0.13512 0.406 xq loss 13 (16%) 67 0.15528 0.431 0.01897 0.123 0.21052 0.502 0.14547 0.424 0.22121 0.504 0.38493 0.66 0.01873 0.123 0.04661 0.217