Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.008	0.231	0.369	13.0	-0.465	10.0	23.0
IHH	0.056	0.091	0.192	17.0	-0.123	7.0	24.0
SHH Np/Cholesterol/GAS1	0.021	0.032	0.144	3.0	-0.157	1.0	4.0
LRPAP1	0.024	0.005	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	-0.021	0.031	0.157	1.0	-0.142	3.0	4.0
SMO/beta Arrestin2	0.026	0.151	0.348	2.0	-0.282	10.0	12.0
SMO	0.01	0.153	0.327	3.0	-0.286	11.0	14.0
AKT1	-0.016	0.122	0.249	1.0	-0.398	2.0	3.0
ARRB2	0.025	0.0	-9999.0	0.0	-9999.0	0.0	0.0
BOC	-0.004	0.093	0.24	1.0	-0.294	7.0	8.0
ADRBK1	0.025	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	0.011	0.152	0.326	3.0	-0.282	11.0	14.0
STIL	-0.001	0.119	0.267	3.0	-0.229	7.0	10.0
DHH N/PTCH2	0.026	0.053	0.185	2.0	-0.206	3.0	5.0
DHH N/PTCH1	0.031	0.141	0.254	9.0	-0.228	13.0	22.0
PIK3CA	0.013	0.05	-9999.0	0.0	-0.294	2.0	2.0
DHH	0.025	0.049	0.24	2.0	-0.294	1.0	3.0
PTHLH	-0.02	0.314	0.432	10.0	-0.706	10.0	20.0
determination of left/right symmetry	0.011	0.152	0.326	3.0	-0.282	11.0	14.0
PIK3R1	0.025	0.003	-9999.0	0.0	-9999.0	0.0	0.0
skeletal system development	-0.019	0.312	0.431	10.0	-0.699	10.0	20.0
IHH N/Hhip	0.044	0.086	0.185	9.0	-0.189	4.0	13.0
DHH N/Hhip	0.038	0.043	0.184	4.0	-0.206	1.0	5.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	0.011	0.152	0.326	3.0	-0.282	11.0	14.0
pancreas development	0.027	0.034	0.239	2.0	-9999.0	0.0	2.0
HHAT	0.024	0.006	-9999.0	0.0	-9999.0	0.0	0.0
PI3K	0.025	0.04	-9999.0	0.0	-0.206	2.0	2.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.027	0.049	0.24	2.0	-0.294	1.0	3.0
somite specification	0.011	0.152	0.326	3.0	-0.282	11.0	14.0
SHH Np/Cholesterol/PTCH1	0.011	0.123	0.213	12.0	-0.236	7.0	19.0
SHH Np/Cholesterol/PTCH2	0.012	0.031	0.127	1.0	-0.157	2.0	3.0
SHH Np/Cholesterol/Megalin	0.015	0.097	0.159	16.0	-0.156	14.0	30.0
SHH	-0.014	0.021	0.171	1.0	-9999.0	0.0	1.0
catabolic process	0.025	0.16	0.282	13.0	-0.254	13.0	26.0
SMO/Vitamin D3	0.02	0.152	0.263	11.0	-0.253	11.0	22.0
SHH Np/Cholesterol/Hhip	0.01	0.037	0.207	2.0	-9999.0	0.0	2.0
LRP2	0.014	0.171	0.24	18.0	-0.294	15.0	33.0
receptor-mediated endocytosis	0.002	0.172	0.285	10.0	-0.318	9.0	19.0
SHH Np/Cholesterol/BOC	0.003	0.054	0.139	2.0	-0.157	7.0	9.0
SHH Np/Cholesterol/CDO	0.019	0.014	0.127	1.0	-9999.0	0.0	1.0
mesenchymal cell differentiation	-0.01	0.037	-9999.0	0.0	-0.205	2.0	2.0
mol:Vitamin D3	0.016	0.145	0.265	11.0	-0.237	7.0	18.0
IHH N/PTCH2	0.029	0.084	0.15	8.0	-0.199	6.0	14.0
CDON	0.024	0.006	-9999.0	0.0	-9999.0	0.0	0.0
IHH N/PTCH1	0.037	0.169	0.306	13.0	-0.255	13.0	26.0
Megalin/LRPAP1	0.024	0.126	0.185	18.0	-0.206	15.0	33.0
PTCH2	0.014	0.05	-9999.0	0.0	-0.294	2.0	2.0
SHH Np/Cholesterol	-0.01	0.014	0.102	1.0	-9999.0	0.0	1.0
PTCH1	0.025	0.161	0.282	13.0	-0.254	13.0	26.0
HHIP	0.027	0.034	0.24	2.0	-9999.0	0.0	2.0