		Clinical Features	Time to Death		YEARS_TO_BIRTH		PATHOLOGIC_STAGE		PATHOLOGY_T_STAGE		PATHOLOGY_N_STAGE		PATHOLOGY_M_STAGE		GENDER		RADIATION_THERAPY		KARNOFSKY_PERFORMANCE_SCORE		NUMBER_PACK_YEARS_SMOKED		NUMBER_OF_LYMPH_NODES		RACE		ETHNICITY	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
TP53	196 (50%)	199	0.92653	1	0.50506	1	0.11037	0.937	0.5783	1	0.01639	0.797	0.53082	1	1	1	0.25223	1	0.29824	1	0.68031	1	0.10175	0.936	0.0015	0.614	1	1
RB1	70 (18%)	325	0.16539	1	0.089164	0.917	0.81138	1	0.44322	1	0.064939	0.9	0.63885	1	0.45156	1	0.54806	1	0.076678	0.907	0.074384	0.9	0.2901	1	0.45342	1	1	1
ELF3	46 (12%)	349	0.48553	1	0.0039871	0.797	0.95357	1	0.41465	1	0.98716	1	1	1	0.28345	1	1	1	0.71767	1	0.82146	1	0.92456	1	1	1	0.6029	1
TSC1	33 (8%)	362	0.4644	1	0.2812	1	0.64967	1	0.3214	1	0.67414	1	0.25892	1	1	1	0.39012	1	0.54211	1	0.2593	1	0.48686	1	0.80142	1	0.50199	1
PIK3CA	86 (22%)	309	0.52361	1	0.62893	1	0.64553	1	0.20598	1	0.24313	1	0.4625	1	1	1	0.26857	1	0.49498	1	0.18321	1	0.017677	0.797	0.19597	1	0.67901	1
RHOB	26 (7%)	369	0.83797	1	0.0611	0.9	0.70979	1	1	1	0.25719	1	0.55946	1	1	1	1	1	0.321	1	0.45134	1	0.77212	1	0.28855	1	1	1
KDM6A	103 (26%)	292	0.50847	1	0.71014	1	0.45908	1	0.70695	1	0.24818	1	0.74406	1	0.8967	1	0.30218	1	0.35324	1	0.1481	1	0.025053	0.797	0.97101	1	0.68568	1
CDKN2A	26 (7%)	369	0.71474	1	0.73482	1	0.37399	1	0.71294	1	1	1	0.50284	1	0.64273	1	1	1	0.86084	1	0.14324	1	0.54546	1	0.91284	1	1	1
ARID1A	97 (25%)	298	0.43543	1	0.38842	1	0.59474	1	0.56306	1	0.17207	1	0.73274	1	0.22903	1	0.42632	1	0.33395	1	0.35107	1	0.7001	1	0.00175	0.614	0.43171	1
STAG2	56 (14%)	339	0.2016	1	0.37597	1	0.10354	0.936	0.39068	1	0.30337	1	0.02292	0.797	0.51047	1	0.50291	1	0.20908	1	0.22541	1	0.16713	1	0.04817	0.852	0.60793	1
ZFP36L1	25 (6%)	370	0.29633	1	0.17764	1	0.1339	1	0.47992	1	0.24828	1	0.039285	0.797	1	1	0.35751	1	0.19421	1	0.81498	1	0.0088562	0.797	1	1	1	1
CDKN1A	35 (9%)	360	0.55358	1	0.95162	1	0.75102	1	0.19295	1	0.56693	1	1	1	0.31101	1	0.68756	1	0.0094132	0.797	0.68881	1	0.47728	1	0.02469	0.797	0.52567	1
EP300	61 (15%)	334	0.073116	0.9	0.2506	1	0.87692	1	0.4444	1	0.25905	1	0.69399	1	0.87473	1	0.22124	1	0.86627	1	0.28809	1	0.65858	1	0.18856	1	1	1
MLL2	114 (29%)	281	0.39032	1	0.089357	0.917	0.51087	1	0.92372	1	0.16502	1	0.30647	1	0.79996	1	1	1	0.755	1	0.58378	1	0.068621	0.9	0.34873	1	1	1
FGFR3	56 (14%)	339	0.16043	1	0.10124	0.936	0.01966	0.797	0.00287	0.756	0.096549	0.927	0.24776	1	0.032874	0.797	0.19639	1	0.051377	0.852	0.1228	0.958	0.54074	1	0.02454	0.797	0.60664	1
ERCC2	38 (10%)	357	0.088358	0.917	0.020092	0.797	0.50626	1	0.94558	1	1	1	1	1	0.56234	1	0.23748	1	0.019203	0.797	0.22501	1	0.3924	1	0.72563	1	0.17495	1
CREBBP	48 (12%)	347	0.47746	1	0.89129	1	0.95559	1	0.38505	1	1	1	0.66307	1	0.15861	1	0.49052	1	0.97366	1	0.83043	1	0.47873	1	1	1	0.60395	1
HRAS	17 (4%)	378	0.35158	1	0.32377	1	0.38635	1	0.10802	0.936	0.67625	1	0.43968	1	0.15819	1	0.57268	1	0.3523	1	0.42332	1	0.87257	1	0.0444	0.85	1	1
FOXA1	14 (4%)	381	0.61658	1	0.839	1	0.12385	0.959	0.36844	1	0.090949	0.917	0.080231	0.915	0.76237	1	0.54724	1	0.071535	0.9	0.030495	0.797	0.02052	0.797	0.69761	1	1	1
KRAS	13 (3%)	382	0.00083268	0.614	0.48937	1	0.41715	1	0.34472	1	0.01232	0.797	1	1	0.19787	1	0.49199	1	0.54623	1	0.11772	0.947	0.31992	1	0.29398	1	1	1
RHOA	18 (5%)	377	0.50243	1	0.45687	1	0.1386	1	0.47864	1	0.43737	1	0.064348	0.9	0.42212	1	0.6127	1	NA	NA	0.0056228	0.797	0.8055	1	0.88653	1	0.28892	1
KIAA1267	24 (6%)	371	0.17606	1	0.12963	0.989	0.67124	1	0.47931	1	0.90803	1	0.55946	1	0.34559	1	0.35751	1	0.96599	1	0.33635	1	0.82019	1	0.33268	1	0.39662	1
MLL	44 (11%)	351	0.87932	1	0.013183	0.797	0.54531	1	0.5037	1	0.83032	1	0.6038	1	0.46711	1	0.71128	1	0.23217	1	0.66897	1	0.27706	1	0.83831	1	0.60589	1
FAT1	50 (13%)	345	0.52697	1	0.020582	0.797	0.1933	1	0.65372	1	0.20211	1	0.32443	1	0.039393	0.797	0.73313	1	0.11521	0.941	0.047811	0.852	0.024298	0.797	0.75955	1	0.29496	1
KLF5	23 (6%)	372	0.51051	1	0.6063	1	0.93311	1	0.1677	1	0.69026	1	1	1	0.32906	1	0.31594	1	0.093342	0.919	0.33889	1	0.77067	1	0.17359	1	1	1
PTEN	14 (4%)	381	0.58665	1	0.67654	1	0.89864	1	0.2015	1	0.55492	1	1	1	0.53376	1	1	1	0.90993	1	0.34524	1	0.60451	1	1	1	1	1
C3ORF70	17 (4%)	378	0.075683	0.906	0.07767	0.909	0.40232	1	0.2277	1	0.31607	1	0.43968	1	1	1	1	1	0.321	1	0.5525	1	0.014733	0.797	0.37076	1	1	1
PSIP1	20 (5%)	375	0.63168	1	0.12223	0.958	0.26962	1	0.11517	0.941	0.26251	1	0.53193	1	0.30702	1	0.25308	1	0.60343	1	0.22168	1	0.19268	1	0.19796	1	1	1
MLL3	74 (19%)	321	0.53917	1	0.86725	1	0.46359	1	0.33686	1	0.94983	1	0.25499	1	0.039205	0.797	0.77717	1	0.12958	0.989	0.42692	1	0.80074	1	0.46284	1	0.3607	1
ASXL2	36 (9%)	359	0.58724	1	0.5787	1	0.7139	1	0.64233	1	0.31892	1	1	1	1	1	0.39467	1	0.63309	1	0.62999	1	0.43488	1	0.70323	1	1	1
ZBTB7B	11 (3%)	384	0.14913	1	0.37966	1	0.81273	1	0.74632	1	0.81631	1	1	1	0.48481	1	1	1	0.37982	1	0.64038	1	0.135	1	0.0282	0.797	1	1
RXRA	24 (6%)	371	0.95365	1	0.10481	0.936	0.43834	1	0.39986	1	0.75266	1	0.53193	1	0.80985	1	1	1	0.15017	1	0.50061	1	0.5137	1	0.25668	1	0.38217	1
FBXW7	30 (8%)	365	0.32286	1	0.087955	0.917	0.31501	1	0.34791	1	0.24356	1	0.32443	1	0.19161	1	0.65603	1	0.72532	1	0.95188	1	0.27522	1	0.63996	1	1	1
RBM10	22 (6%)	373	0.72189	1	0.52345	1	0.47003	1	0.58258	1	0.10848	0.936	1	1	1	1	0.61422	1	0.93988	1	0.47292	1	0.13754	1	0.88728	1	1	1
NFE2L2	24 (6%)	371	0.3163	1	0.72306	1	0.1493	1	0.062349	0.9	0.82343	1	0.11528	0.941	0.029156	0.797	1	1	0.6858	1	0.67716	1	0.4657	1	0.071279	0.9	1	1
CUL1	19 (5%)	376	0.84392	1	0.57911	1	0.73116	1	0.78183	1	0.3329	1	1	1	0.79102	1	0.6127	1	0.41752	1	0.1697	1	0.47982	1	0.87846	1	0.33698	1
HLA-A	5 (1%)	390	0.4715	1	0.87745	1	0.39828	1	0.03599	0.797	0.68268	1	1	1	1	1	1	1	NA	NA	NA	NA	0.87687	1	1	1	1	1
GNA13	12 (3%)	383	0.69633	1	0.61369	1	0.63892	1	0.63695	1	0.70815	1	1	1	0.31146	1	1	1	0.071535	0.9	0.71688	1	0.19497	1	0.5573	1	0.22012	1
NUDT11	7 (2%)	388	0.80931	1	0.13999	1	1	1	0.51011	1	0.73119	1	1	1	0.19785	1	1	1	NA	NA	NA	NA	0.98546	1	1	1	1	1
MBD1	12 (3%)	383	0.46987	1	0.59929	1	0.16198	1	1	1	0.34066	1	1	1	0.31146	1	0.49199	1	0.040879	0.797	0.43742	1	0.092357	0.917	0.40096	1	1	1
SCARF2	8 (2%)	387	0.27859	1	0.14408	1	0.35706	1	1	1	0.45933	1	1	1	0.43082	1	1	1	0.96954	1	0.6461	1	0.44392	1	0.75768	1	1	1
FOXQ1	14 (4%)	381	0.28842	1	0.38547	1	0.64801	1	1	1	0.32713	1	1	1	0.76237	1	1	1	NA	NA	0.070366	0.9	0.63502	1	0.71751	1	1	1
FAM47C	21 (5%)	374	0.083424	0.915	0.77436	1	0.39832	1	0.95042	1	0.03922	0.797	1	1	0.036244	0.797	0.61422	1	0.84553	1	0.98906	1	0.072426	0.9	0.89006	1	0.38217	1
METTL3	17 (4%)	378	0.072724	0.9	0.89171	1	0.37319	1	0.35799	1	0.947	1	1	1	0.57643	1	0.59675	1	0.096389	0.927	0.24806	1	0.14527	1	0.31391	1	1	1
ZNF185	5 (1%)	390	0.96508	1	0.38006	1	0.47903	1	1	1	0.46292	1	1	1	0.33361	1	1	1	NA	NA	NA	NA	0.10727	0.936	1	1	1	1
ERBB2	48 (12%)	347	0.031304	0.797	0.26689	1	0.6256	1	0.93159	1	0.46803	1	0.60658	1	0.72625	1	0.48906	1	0.67961	1	0.91542	1	0.19083	1	0.72401	1	1	1
ATM	53 (13%)	342	0.32391	1	0.66343	1	0.74789	1	0.79754	1	0.36213	1	0.3679	1	0.24137	1	1	1	0.083396	0.915	0.21641	1	0.21637	1	0.3487	1	0.31259	1
UNC93B1	7 (2%)	388	0.30455	1	0.53648	1	0.59079	1	0.53653	1	0.32975	1	1	1	0.19785	1	1	1	NA	NA	NA	NA	0.30136	1	1	1	1	1
SF1	10 (3%)	385	0.51099	1	0.087872	0.917	0.1147	0.941	1	1	0.01434	0.797	1	1	0.070084	0.9	1	1	0.70098	1	0.3344	1	0.057465	0.89	0.62024	1	1	1
BCL2L1	4 (1%)	391	0.027541	0.797	0.74555	1	0.34571	1	0.28876	1	1	1	1	1	0.57633	1	1	1	NA	NA	NA	NA	0.9408	1	1	1	1	1
DNAH6	16 (4%)	379	0.95746	1	0.94369	1	0.21337	1	0.159	1	0.63649	1	1	1	0.77089	1	0.54724	1	0.7474	1	0.76161	1	0.072328	0.9	0.87432	1	0.28892	1
HES1	11 (3%)	384	0.37497	1	0.051925	0.852	0.93311	1	1	1	0.64064	1	1	1	0.7358	1	1	1	NA	NA	0.16479	1	0.55933	1	0.4023	1	1	1
ERBB3	41 (10%)	354	0.43662	1	0.7405	1	0.52547	1	0.76912	1	0.50604	1	0.60658	1	0.19325	1	0.70726	1	0.074	0.9	0.74199	1	0.53206	1	0.059239	0.895	0.19144	1
TXNIP	17 (4%)	378	0.92555	1	0.2096	1	0.76754	1	0.22962	1	0.82663	1	1	1	1	1	0.6127	1	0.19498	1	0.93343	1	0.67413	1	0.063029	0.9	0.27224	1
THRAP3	14 (4%)	381	0.44227	1	0.091429	0.917	0.20432	1	0.80147	1	0.48667	1	1	1	0.76237	1	0.54724	1	0.6857	1	0.2572	1	0.038421	0.797	0.41685	1	0.033911	0.797
SPTAN1	45 (11%)	350	0.049579	0.852	0.052581	0.852	0.41691	1	0.21914	1	0.59609	1	1	1	0.10545	0.936	1	1	0.96346	1	0.38739	1	0.32294	1	0.5972	1	0.22524	1
ARID1B	23 (6%)	372	0.85208	1	0.3589	1	0.4328	1	0.40856	1	0.27398	1	0.19472	1	1	1	0.62053	1	0.6857	1	0.051769	0.852	0.10493	0.936	0.38372	1	1	1
NRAS	7 (2%)	388	0.20705	1	0.37013	1	0.33351	1	0.45549	1	0.52802	1	1	1	0.19785	1	1	1	NA	NA	0.19348	1	0.36172	1	0.081169	0.915	1	1
RPTN	15 (4%)	380	0.94909	1	0.99077	1	0.26521	1	0.8526	1	0.088869	0.917	1	1	0.76845	1	0.57268	1	0.89519	1	0.045984	0.852	0.14497	1	0.51615	1	1	1
RAI1	21 (5%)	374	0.10079	0.936	0.76908	1	0.63006	1	1	1	0.12234	0.958	0.11528	0.941	0.30639	1	0.61693	1	0.66454	1	0.81411	1	0.14089	1	1	1	0.32129	1
TMCO4	12 (3%)	383	0.92991	1	0.8549	1	0.68251	1	0.49631	1	0.70833	1	0.47212	1	0.73855	1	1	1	0.41752	1	0.63577	1	0.72543	1	0.03327	0.797	1	1
CNOT1	21 (5%)	374	0.011776	0.797	0.39194	1	0.19384	1	0.48341	1	0.7549	1	1	1	0.30639	1	0.61693	1	0.026902	0.797	0.017651	0.797	0.21431	1	0.62921	1	0.0067432	0.797
PARD3	22 (6%)	373	0.29442	1	0.70557	1	0.58635	1	0.23671	1	0.27727	1	1	1	0.021132	0.797	0.61693	1	0.0094471	0.797	0.5709	1	0.3492	1	0.28335	1	0.078674	0.91
EZR	12 (3%)	383	0.015488	0.797	0.43213	1	0.34494	1	0.33968	1	0.51252	1	0.29098	1	0.5158	1	0.49199	1	0.321	1	0.15379	1	0.135	1	0.20498	1	1	1
MOAP1	7 (2%)	388	0.040804	0.797	0.10743	0.936	0.8086	1	0.86083	1	1	1	1	1	1	1	0.28521	1	0.24635	1	0.6058	1	1	1	0.71246	1	1	1
SF3B1	24 (6%)	371	0.52135	1	0.034974	0.797	0.18582	1	0.5191	1	0.72035	1	1	1	0.15209	1	0.62494	1	0.0096827	0.797	0.94146	1	0.83857	1	0.39537	1	1	1
RUNX1	13 (3%)	382	0.55392	1	0.72867	1	0.44526	1	0.23932	1	0.7073	1	1	1	0.52834	1	0.46202	1	0.68687	1	0.9468	1	0.092157	0.917	0.48293	1	1	1
MEGF8	20 (5%)	375	0.31997	1	0.75541	1	0.49774	1	0.62348	1	0.43244	1	1	1	0.11866	0.947	0.61254	1	0.82886	1	0.028453	0.797	0.24211	1	0.53675	1	0.30527	1
CASP8	14 (4%)	381	0.23113	1	0.79072	1	0.30298	1	0.71907	1	0.59047	1	1	1	1	1	1	1	0.89519	1	0.56849	1	0.56278	1	0.83784	1	1	1
DAZAP1	6 (2%)	389	0.35687	1	0.91366	1	0.051839	0.852	0.21479	1	1	1	1	1	1	1	1	1	0.321	1	0.20626	1	0.71169	1	1	1	1	1
USP28	13 (3%)	382	0.47079	1	0.95751	1	1	1	0.92747	1	0.42026	1	0.3693	1	1	1	1	1	0.14096	1	0.53521	1	0.47847	1	0.83735	1	1	1
SETD2	27 (7%)	368	0.61509	1	0.8376	1	0.52913	1	0.80689	1	0.4955	1	1	1	0.82084	1	1	1	0.049898	0.852	0.032102	0.797	0.70005	1	0.76519	1	1	1
EME1	5 (1%)	390	0.65769	1	0.0554	0.871	0.46698	1	0.57492	1	1	1	1	1	1	1	1	1	NA	NA	NA	NA	NA	NA	0.33215	1	1	1
ADC	5 (1%)	390	0.48108	1	0.2144	1	0.46785	1	0.57732	1	1	1	1	1	1	1	1	1	0.47685	1	NA	NA	0.92527	1	0.33129	1	1	1
CNOT3	10 (3%)	385	0.10842	0.936	0.49676	1	0.92882	1	1	1	0.68441	1	0.3693	1	0.46393	1	1	1	NA	NA	0.72106	1	0.8829	1	0.24604	1	1	1
SSH3	15 (4%)	380	0.096866	0.927	0.28738	1	0.43032	1	0.15722	1	0.2206	1	1	1	0.76845	1	1	1	NA	NA	0.65595	1	0.20034	1	0.59801	1	1	1
AHR	22 (6%)	373	0.31832	1	0.95849	1	0.20516	1	0.3625	1	0.43549	1	0.47212	1	0.61587	1	1	1	0.64861	1	0.88507	1	0.97056	1	1	1	0.36742	1
EIF4A2	11 (3%)	384	0.50071	1	0.93149	1	0.61795	1	0.20188	1	0.52085	1	0.33118	1	0.3019	1	1	1	0.56685	1	0.79227	1	0.66884	1	0.76798	1	1	1
EPHA2	19 (5%)	376	0.57856	1	0.11005	0.937	0.52007	1	0.36064	1	0.01453	0.797	0.3693	1	0.055165	0.871	0.61199	1	0.53264	1	0.19384	1	0.99862	1	0.11813	0.947	1	1
OGDH	19 (5%)	376	0.2298	1	0.34143	1	0.88653	1	0.94092	1	1	1	1	1	0.42378	1	1	1	0.47601	1	0.28978	1	0.54546	1	0.27804	1	0.33698	1
POU3F1	3 (1%)	392	0.33357	1	0.69314	1	0.083209	0.915	0.57633	1	0.059489	0.895	NA	NA	1	1	1	1	NA	NA	NA	NA	0.027503	0.797	1	1	1	1
