		Clinical Features	Time to Death		YEARS_TO_BIRTH		PATHOLOGIC_STAGE		PATHOLOGY_T_STAGE		PATHOLOGY_N_STAGE		PATHOLOGY_M_STAGE		GENDER		RADIATION_THERAPY		HISTOLOGICAL_TYPE		NUMBER_PACK_YEARS_SMOKED		YEAR_OF_TOBACCO_SMOKING_ONSET		NUMBER_OF_LYMPH_NODES		RACE		ETHNICITY	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
TP53	364 (71%)	147	0.0069577	0.287	0.53016	1	0.50248	1	0.01866	0.476	0.62655	1	1	1	0.91273	1	0.32827	1	0.0072799	0.287	0.11378	0.87	0.72327	1	0.60295	1	0.32846	1	0.068483	0.791
CDKN2A	112 (22%)	399	0.9963	1	0.11204	0.87	0.16826	0.907	0.81169	1	0.39811	1	1	1	0.90422	1	0.54836	1	0.25364	0.961	0.64789	1	0.40206	1	0.22414	0.933	0.49529	1	0.47363	1
NSD1	62 (12%)	449	0.037946	0.6	0.091159	0.851	0.16243	0.907	0.40381	1	0.03355	0.6	0.14063	0.907	0.17079	0.907	1	1	0.42679	1	0.11504	0.87	0.40144	1	0.00012362	0.0358	0.76467	1	0.2064	0.933
CASP8	54 (11%)	457	0.063221	0.773	7.616e-09	6.61e-06	0.72549	1	0.46333	1	0.082419	0.836	1	1	0.00052251	0.113	0.085413	0.842	0.65008	1	0.062919	0.773	0.019856	0.479	0.023168	0.503	0.43524	1	0.33973	1
MLL2	81 (16%)	430	0.12533	0.876	0.28948	0.986	0.35522	1	0.21535	0.933	0.76936	1	1	1	1	1	0.78917	1	0.47735	1	0.44913	1	0.86643	1	0.94488	1	0.113	0.87	0.40057	1
TGFBR2	24 (5%)	487	0.86173	1	0.10871	0.87	0.94904	1	0.70479	1	0.70424	1	1	1	1	1	0.48416	1	1	1	0.386	1	0.23014	0.933	0.48965	1	0.8458	1	1	1
HLA-B	24 (5%)	487	0.96278	1	0.19694	0.933	0.7509	1	0.37064	1	0.03017	0.6	1	1	0.10371	0.87	0.16745	0.907	0.41511	1	0.22501	0.933	0.12887	0.876	0.28689	0.986	0.60437	1	0.61439	1
FBXW7	33 (6%)	478	0.31809	1	0.006675	0.287	0.7479	1	0.41962	1	0.32375	1	1	1	0.10669	0.87	0.32647	1	1	1	0.32317	1	0.96733	1	0.17017	0.907	1	1	0.65958	1
NOTCH1	90 (18%)	421	0.1001	0.87	0.0087753	0.293	0.35385	1	0.29566	0.991	0.67388	1	0.17188	0.907	0.089352	0.851	0.020413	0.479	1	1	0.055091	0.736	0.18524	0.907	0.35972	1	0.93328	1	0.18755	0.909
FAT1	112 (22%)	399	0.38875	1	2.3148e-07	1e-04	0.35352	1	0.02276	0.503	0.20744	0.933	0.22917	0.933	0.0036546	0.227	0.71867	1	0.76586	1	0.079919	0.83	0.0087062	0.293	0.35971	1	0.58702	1	0.45032	1
JUB	34 (7%)	477	0.024467	0.518	0.0025437	0.184	0.65069	1	0.60614	1	0.22419	0.933	1	1	0.69483	1	0.84656	1	1	1	0.2144	0.933	0.0029003	0.194	0.47036	1	0.27522	0.983	0.67433	1
ZNF750	21 (4%)	490	0.97439	1	0.1348	0.893	0.20998	0.933	0.5589	1	0.22721	0.933	1	1	0.21747	0.933	0.47285	1	0.37254	1	0.76466	1	0.5408	1	0.034752	0.6	0.17772	0.907	0.61763	1
NFE2L2	27 (5%)	484	0.28337	0.986	0.0018259	0.158	0.72616	1	0.73036	1	0.66725	1	1	1	0.11826	0.87	0.089952	0.851	1	1	0.49689	1	0.37691	1	0.51003	1	0.41713	1	0.34557	1
HLA-A	22 (4%)	489	0.75486	1	0.075819	0.812	0.88392	1	0.073709	0.8	0.41602	1	1	1	1	1	0.13024	0.876	1	1	0.43949	1	0.011723	0.377	0.55857	1	0.67041	1	0.61439	1
EPHA2	24 (5%)	487	0.29314	0.991	0.084586	0.842	0.87442	1	0.65344	1	0.51841	1	1	1	0.48363	1	0.16745	0.907	1	1	0.047793	0.703	0.18389	0.907	0.93348	1	0.58679	1	1	1
RAC1	15 (3%)	496	0.48498	1	0.0011667	0.113	0.21582	0.933	0.18037	0.907	0.35857	1	1	1	0.006534	0.287	1	1	1	1	0.708	1	0.0043391	0.235	0.17859	0.907	0.20782	0.933	1	1
HRAS	31 (6%)	480	0.24743	0.961	0.39682	1	0.409	1	0.65005	1	0.14125	0.907	1	1	0.061418	0.773	0.21971	0.933	0.4997	1	0.73349	1	0.46371	1	0.080106	0.83	0.38786	1	0.39519	1
EP300	38 (7%)	473	0.24669	0.961	0.54064	1	0.98832	1	0.50362	1	0.38803	1	1	1	0.56894	1	0.70498	1	0.57888	1	0.11452	0.87	0.91055	1	0.69537	1	0.82375	1	1	1
OR6C65	16 (3%)	495	0.24301	0.961	0.98487	1	0.52793	1	0.93736	1	0.87376	1	1	1	0.25654	0.961	0.27819	0.985	1	1	0.57986	1	0.44302	1	0.9169	1	0.5732	1	1	1
PIK3CA	94 (18%)	417	0.82846	1	0.87923	1	0.28961	0.986	0.32397	1	0.10423	0.87	1	1	0.054483	0.736	0.8989	1	0.75284	1	0.8032	1	0.7974	1	0.5084	1	0.090939	0.851	0.59535	1
PTEN	14 (3%)	497	0.205	0.933	0.3196	1	0.93541	1	0.28964	0.986	0.49097	1	1	1	1	1	0.77884	1	1	1	0.42611	1	0.14996	0.907	0.49637	1	0.56266	1	1	1
RASA1	18 (4%)	493	0.50687	1	0.34724	1	0.11754	0.87	0.37648	1	0.7333	1	0.036458	0.6	0.42278	1	0.30578	1	1	1	0.16164	0.907	0.8534	1	0.36058	1	0.61974	1	1	1
MAPK1	9 (2%)	502	0.16079	0.907	0.94994	1	0.86857	1	0.41236	1	0.65017	1	1	1	0.70809	1	0.72551	1	1	1	NA	NA	0.4602	1	0.86501	1	0.23884	0.961	1	1
NUDT11	9 (2%)	502	0.25405	0.961	0.35101	1	0.57959	1	0.75822	1	0.64911	1	1	1	0.12183	0.876	0.096108	0.851	1	1	0.58438	1	0.29533	0.991	0.50427	1	1	1	0.38856	1
KDM6A	17 (3%)	494	0.26014	0.961	0.053405	0.736	0.39917	1	0.25772	0.961	0.8039	1	1	1	1	1	0.78392	1	1	1	0.14611	0.907	0.17907	0.907	0.87554	1	0.4906	1	1	1
RB1	17 (3%)	494	0.071958	0.791	0.35312	1	0.15413	0.907	0.22589	0.933	0.57955	1	1	1	0.001043	0.113	0.79552	1	1	1	0.68647	1	0.28135	0.985	0.2008	0.933	0.24546	0.961	0.58579	1
KEAP1	22 (4%)	489	0.7648	1	0.096011	0.851	0.1509	0.907	0.0078199	0.293	0.36988	1	1	1	0.14412	0.907	0.015903	0.454	0.10538	0.87	0.094343	0.851	0.30199	1	0.87126	1	0.68998	1	0.61439	1
KRT17	6 (1%)	505	0.2098	0.933	0.64253	1	0.25917	0.961	0.18607	0.907	0.050729	0.722	NA	NA	0.35091	1	0.61358	1	1	1	0.90069	1	0.94489	1	0.12162	0.876	0.53589	1	1	1
RHOA	10 (2%)	501	0.51161	1	0.38999	1	1	1	0.38564	1	0.03671	0.6	1	1	0.47036	1	0.50535	1	0.1995	0.933	0.69597	1	0.57249	1	0.34323	1	0.69146	1	1	1
PTPN14	16 (3%)	495	0.15385	0.907	0.828	1	0.04094	0.623	0.85236	1	0.2489	0.961	0.036458	0.6	0.77525	1	0.59117	1	1	1	0.73833	1	0.5925	1	0.41214	1	0.061869	0.773	0.58579	1
KRTAP5-5	4 (1%)	507	0.73014	1	0.42523	1	0.064919	0.783	0.19163	0.919	1	1	1	1	0.29566	0.991	1	1	1	1	0.58391	1	0.26717	0.97	0.80396	1	1	1	1	1
ZNF623	12 (2%)	499	0.3107	1	0.64332	1	1	1	0.78749	1	0.7944	1	1	1	0.74227	1	0.75438	1	1	1	0.80347	1	0.57811	1	0.2425	0.961	0.49944	1	1	1
TIGD4	7 (1%)	504	0.32003	1	0.17539	0.907	0.25312	0.961	0.77581	1	0.17073	0.907	1	1	0.68037	1	0.6621	1	1	1	0.50057	1	0.40343	1	0.16688	0.907	0.58911	1	1	1
NAP1L2	7 (1%)	504	0.93238	1	0.25889	0.961	0.77985	1	1	1	0.77339	1	1	1	0.39418	1	1	1	0.14158	0.907	0.24943	0.961	0.42346	1	0.8869	1	1	1	0.0023437	0.184
CUL3	16 (3%)	495	0.92391	1	0.3773	1	0.24046	0.961	0.15997	0.907	0.94817	1	1	1	0.25654	0.961	0.78392	1	1	1	0.77579	1	0.33559	1	0.28455	0.986	0.0366	0.6	1	1
CREBBP	34 (7%)	477	0.5073	1	0.016754	0.454	0.75336	1	0.72989	1	0.88706	1	1	1	0.54847	1	1	1	0.53679	1	0.71481	1	0.035126	0.6	0.68851	1	0.10355	0.87	1	1
VEZF1	8 (2%)	503	0.52955	1	0.94407	1	0.0129	0.386	0.01666	0.454	0.065959	0.784	1	1	1	1	0.05347	0.736	0.16067	0.907	0.70699	1	0.55823	1	0.18903	0.912	1	1	0.3539	1
MLL4	19 (4%)	492	0.31187	1	0.00086603	0.113	0.19408	0.926	0.92261	1	0.086439	0.843	1	1	0.18428	0.907	0.4507	1	1	1	0.64216	1	0.050249	0.722	0.14411	0.907	0.44124	1	0.61439	1
IRS4	17 (3%)	494	0.73334	1	0.93127	1	0.69816	1	0.78633	1	0.3887	1	1	1	0.26348	0.961	0.55641	1	1	1	0.80232	1	0.91068	1	0.14399	0.907	0.75788	1	0.18427	0.907
HUWE1	46 (9%)	465	0.41703	1	0.41879	1	0.84238	1	0.61897	1	0.49221	1	1	1	0.035155	0.6	0.86259	1	1	1	0.2613	0.961	0.58093	1	0.52025	1	0.03961	0.614	0.27512	0.983
THSD7A	32 (6%)	479	0.67626	1	0.70446	1	0.95111	1	0.21514	0.933	0.90174	1	1	1	0.41007	1	0.3096	1	0.51149	1	0.0046624	0.238	0.52083	1	0.069027	0.791	0.5504	1	0.67433	1
C3ORF59	10 (2%)	501	0.94726	1	0.39059	1	0.9543	1	0.75726	1	0.35894	1	1	1	0.73397	1	0.27119	0.981	1	1	0.64984	1	0.72745	1	0.53878	1	1	1	1	1
DYSF	20 (4%)	491	0.73318	1	0.061384	0.773	0.96046	1	0.6584	1	0.094179	0.851	1	1	0.79819	1	1	1	1	1	0.026507	0.548	0.10736	0.87	0.071759	0.791	0.82344	1	0.61439	1
ZNF233	9 (2%)	502	0.31422	1	0.2807	0.985	0.39191	1	0.46784	1	0.22793	0.933	NA	NA	1	1	1	1	1	1	0.070248	0.791	0.11578	0.87	0.0084084	0.293	0.68441	1	1	1
KIAA1267	11 (2%)	500	0.45849	1	0.26295	0.961	0.47365	1	0.21976	0.933	0.88911	1	1	1	0.49832	1	0.75438	1	1	1	0.88442	1	0.46889	1	0.48908	1	0.69575	1	0.10971	0.87
ASXL1	16 (3%)	495	0.28779	0.986	0.83674	1	0.51702	1	0.17498	0.907	0.12417	0.876	1	1	0.77525	1	0.0055714	0.269	1	1	0.94898	1	0.78195	1	0.83551	1	0.77209	1	1	1
SMAD4	13 (3%)	498	0.60164	1	0.3044	1	0.77052	1	1	1	0.61783	1	1	1	1	1	0.5263	1	1	1	0.40241	1	0.17069	0.907	0.90166	1	1	1	1	1
GAGE2A	4 (1%)	507	0.90415	1	0.30665	1	0.64226	1	0.79668	1	1	1	1	1	0.57831	1	0.27977	0.985	1	1	NA	NA	NA	NA	0.75482	1	0.39658	1	1	1
EMG1	3 (1%)	508	0.66319	1	0.81202	1	0.81736	1	0.85049	1	0.11777	0.87	1	1	0.17887	0.907	0.27977	0.985	1	1	NA	NA	NA	NA	0.57758	1	1	1	1	1
PIK3R1	8 (2%)	503	0.12901	0.876	0.93637	1	0.52094	1	0.79715	1	0.15567	0.907	1	1	0.68882	1	0.71916	1	1	1	0.91367	1	0.96224	1	0.16688	0.907	1	1	1	1
KRTAP5-7	5 (1%)	506	0.1693	0.907	0.49532	1	0.40452	1	0.7822	1	0.68913	1	1	1	0.12474	0.876	0.34803	1	1	1	0.95923	1	0.77152	1	0.3467	1	0.18394	0.907	1	1
SLC9A6	5 (1%)	506	0.012899	0.386	0.77779	1	0.32614	1	0.45578	1	0.12992	0.876	1	1	0.12474	0.876	0.6621	1	1	1	0.8488	1	NA	NA	0.14995	0.907	1	1	1	1
ELF4	7 (1%)	504	0.37385	1	0.92179	1	0.01737	0.457	0.072019	0.791	0.21672	0.933	1	1	0.68037	1	0.021275	0.486	1	1	0.42325	1	0.87418	1	0.060461	0.773	1	1	1	1
CTCF	15 (3%)	496	0.035547	0.6	0.0010653	0.113	0.16135	0.907	1	1	0.4121	1	1	1	0.033776	0.6	0.77441	1	1	1	0.98065	1	0.038027	0.6	0.32561	1	0.34347	1	1	1
HNRNPL	11 (2%)	500	0.48041	1	0.10452	0.87	0.30169	1	0.31932	1	0.10396	0.87	1	1	0.1771	0.907	1	1	0.21325	0.933	0.2612	0.961	0.7919	1	0.21406	0.933	1	1	1	1
ZFP36L2	8 (2%)	503	0.13146	0.878	0.55177	1	0.76605	1	0.88072	1	0.30657	1	NA	NA	0.45066	1	1	1	1	1	0.66096	1	0.20112	0.933	0.86797	1	1	1	0.3539	1
MYH9	21 (4%)	490	0.76469	1	0.81872	1	0.86213	1	0.38379	1	0.89274	1	1	1	0.21747	0.933	0.47345	1	0.37345	1	0.46778	1	0.36129	1	0.86217	1	0.43973	1	0.24421	0.961
NOTCH2	21 (4%)	490	0.54511	1	0.14704	0.907	0.33304	1	0.77968	1	0.69162	1	1	1	0.0039832	0.23	0.60887	1	1	1	0.12923	0.876	0.15795	0.907	0.51372	1	0.83056	1	0.61763	1
NCOR1	17 (3%)	494	0.8776	1	0.17765	0.907	0.75882	1	0.56867	1	0.68607	1	1	1	0.41549	1	0.39	1	1	1	0.79976	1	0.26149	0.961	0.34629	1	0.78783	1	0.22403	0.933
AK5	13 (3%)	498	0.00092273	0.113	0.32552	1	0.76847	1	0.38313	1	0.65735	1	1	1	0.35106	1	1	1	1	1	0.81569	1	0.54312	1	0.45598	1	0.49999	1	0.092705	0.851
SPTY2D1	10 (2%)	501	0.4707	1	0.019657	0.479	0.86705	1	0.6236	1	0.78614	1	1	1	0.73397	1	0.3286	1	1	1	0.042075	0.63	0.22109	0.933	0.22491	0.933	1	1	0.42143	1
PIWIL2	8 (2%)	503	0.55469	1	0.27503	0.983	0.56578	1	0.71126	1	1	1	1	1	1	1	0.699	1	1	1	0.082833	0.836	0.080353	0.83	0.55437	1	1	1	1	1
