This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and molecular subtypes.
Testing the association between copy number variation 80 arm-level events and 12 molecular subtypes across 528 patients, 443 significant findings detected with P value < 0.05 and Q value < 0.25.
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1p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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1q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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2p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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2q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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3p gain cnv correlated to 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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3q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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4p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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4q gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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5p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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5q gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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6p gain cnv correlated to 'MIRSEQ_CHIERARCHICAL'.
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7p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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7q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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8p gain cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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8q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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9p gain cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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9q gain cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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10p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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10q gain cnv correlated to 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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11p gain cnv correlated to 'MRNASEQ_CNMF'.
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12p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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12q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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13q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CNMF'.
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14q gain cnv correlated to 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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15q gain cnv correlated to 'CN_CNMF' and 'RPPA_CHIERARCHICAL'.
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16p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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16q gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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17p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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17q gain cnv correlated to 'MRNA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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18p gain cnv correlated to 'METHLYATION_CNMF'.
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18q gain cnv correlated to 'METHLYATION_CNMF'.
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19p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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19q gain cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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20p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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21q gain cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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22q gain cnv correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_CNMF'.
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xp gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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xq gain cnv correlated to 'CN_CNMF' and 'RPPA_CNMF'.
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1p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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1q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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2p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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2q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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3p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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3q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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4p loss cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4q loss cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5p loss cnv correlated to 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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5q loss cnv correlated to 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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6p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6q loss cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8p loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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8q loss cnv correlated to 'METHLYATION_CNMF' and 'RPPA_CNMF'.
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9p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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9q loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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10p loss cnv correlated to 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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10q loss cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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11p loss cnv correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_CHIERARCHICAL'.
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11q loss cnv correlated to 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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12p loss cnv correlated to 'CN_CNMF'.
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13q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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14q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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15q loss cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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16p loss cnv correlated to 'RPPA_CHIERARCHICAL' and 'MIRSEQ_CHIERARCHICAL'.
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16q loss cnv correlated to 'CN_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
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17p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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17q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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18p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19p loss cnv correlated to 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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20p loss cnv correlated to 'MIRSEQ_CNMF'.
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21q loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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22q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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xp loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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xq loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 80 arm-level events and 12 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 443 significant findings detected.
|
Clinical Features |
MRNA CNMF |
MRNA CHIERARCHICAL |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| 3q gain | 60 (11%) | 468 |
0.0214 (0.0564) |
0.0305 (0.0741) |
0.0103 (0.0316) |
4e-05 (0.00028) |
1e-05 (8.42e-05) |
2e-05 (0.000155) |
4e-05 (0.00028) |
2e-05 (0.000155) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.00019 (0.00107) |
0.405 (0.548) |
| 12p gain | 121 (23%) | 407 |
0.0219 (0.0572) |
0.0328 (0.0775) |
4e-05 (0.00028) |
0.00016 (0.00092) |
1e-05 (8.42e-05) |
3e-05 (0.000218) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.00176 (0.00725) |
0.204 (0.33) |
| 12q gain | 122 (23%) | 406 |
0.0211 (0.0563) |
0.0329 (0.0775) |
3e-05 (0.000218) |
0.00014 (0.000815) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.00236 (0.00932) |
0.264 (0.397) |
| 3p loss | 379 (72%) | 149 |
0.00612 (0.0205) |
0.0103 (0.0316) |
1e-05 (8.42e-05) |
0.00942 (0.0296) |
0.0113 (0.0338) |
0.00016 (0.00092) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.0149 (0.0432) |
0.00419 (0.0153) |
0.0236 (0.0606) |
0.77 (0.891) |
| 6p loss | 100 (19%) | 428 |
0.0313 (0.0756) |
0.0142 (0.0415) |
1e-05 (8.42e-05) |
0.00315 (0.0121) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.173 (0.288) |
0.0304 (0.074) |
| 9p loss | 149 (28%) | 379 |
0.00706 (0.023) |
0.0362 (0.0829) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.0109 (0.033) |
0.0593 (0.125) |
| 14q loss | 216 (41%) | 312 |
1e-05 (8.42e-05) |
6e-05 (0.000392) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.0131 (0.0388) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.256 (0.39) |
0.0441 (0.0978) |
| 22q loss | 39 (7%) | 489 |
0.0215 (0.0565) |
0.0013 (0.00557) |
0.0175 (0.0489) |
0.00998 (0.0311) |
0.00041 (0.00208) |
0.0211 (0.0563) |
1e-05 (8.42e-05) |
2e-05 (0.000155) |
5e-05 (0.000343) |
0.00108 (0.00478) |
0.0384 (0.0867) |
0.253 (0.389) |
| 20p gain | 112 (21%) | 416 |
0.243 (0.377) |
0.117 (0.21) |
1e-05 (8.42e-05) |
8e-05 (0.000505) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
4e-05 (0.00028) |
0.0361 (0.0828) |
| 20q gain | 115 (22%) | 413 |
0.096 (0.18) |
0.0739 (0.148) |
1e-05 (8.42e-05) |
6e-05 (0.000392) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
3e-05 (0.000218) |
0.0209 (0.0562) |
| 1q loss | 37 (7%) | 491 |
0.0381 (0.0863) |
0.0115 (0.0341) |
0.00011 (0.00066) |
0.0108 (0.0327) |
0.0184 (0.0507) |
0.00419 (0.0153) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.0322 (0.0767) |
0.0102 (0.0316) |
0.276 (0.412) |
0.62 (0.753) |
| 2p loss | 14 (3%) | 514 |
8e-05 (0.000505) |
0.00045 (0.00226) |
0.0336 (0.0786) |
0.0221 (0.0578) |
0.00062 (0.00298) |
0.0002 (0.00111) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
7e-05 (0.000448) |
1e-05 (8.42e-05) |
0.159 (0.268) |
0.376 (0.521) |
| 2q loss | 14 (3%) | 514 |
0.0004 (0.00204) |
0.00083 (0.00381) |
0.0102 (0.0316) |
0.0294 (0.0721) |
0.00344 (0.0131) |
0.00017 (0.000966) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.0001 (0.000604) |
1e-05 (8.42e-05) |
0.16 (0.27) |
0.378 (0.523) |
| 9q loss | 151 (29%) | 377 |
0.0191 (0.052) |
0.0582 (0.123) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.00256 (0.0101) |
0.0959 (0.18) |
| 13q loss | 70 (13%) | 458 |
0.00662 (0.0218) |
0.0462 (0.102) |
0.024 (0.0612) |
0.00094 (0.00424) |
1e-05 (8.42e-05) |
2e-05 (0.000155) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.19 (0.312) |
0.43 (0.571) |
| 18p loss | 93 (18%) | 435 |
0.0915 (0.174) |
0.459 (0.598) |
0.00056 (0.00272) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.00084 (0.00384) |
0.00667 (0.0219) |
| 18q loss | 95 (18%) | 433 |
0.075 (0.149) |
0.221 (0.351) |
0.00034 (0.00177) |
6e-05 (0.000392) |
1e-05 (8.42e-05) |
2e-05 (0.000155) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.00927 (0.0293) |
0.0322 (0.0767) |
| 8q gain | 61 (12%) | 467 |
0.334 (0.474) |
0.104 (0.192) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
6e-05 (0.000392) |
2e-05 (0.000155) |
0.775 (0.896) |
| 1p loss | 60 (11%) | 468 |
0.00363 (0.0137) |
0.00568 (0.0193) |
0.00569 (0.0193) |
0.433 (0.571) |
0.0135 (0.0397) |
0.0108 (0.0327) |
3e-05 (0.000218) |
6e-05 (0.000392) |
0.00315 (0.0121) |
0.0249 (0.0634) |
0.0663 (0.136) |
0.314 (0.454) |
| 17p loss | 46 (9%) | 482 |
0.00021 (0.00115) |
0.00017 (0.000966) |
0.0243 (0.0619) |
0.0552 (0.118) |
0.00056 (0.00272) |
3e-05 (0.000218) |
2e-05 (0.000155) |
1e-05 (8.42e-05) |
2e-05 (0.000155) |
9e-05 (0.000561) |
0.346 (0.486) |
0.17 (0.285) |
| xq loss | 45 (9%) | 483 |
0.0408 (0.0915) |
0.0187 (0.0512) |
0.0002 (0.00111) |
0.00328 (0.0126) |
0.612 (0.744) |
0.033 (0.0776) |
0.0141 (0.041) |
0.0418 (0.0936) |
0.0144 (0.0417) |
0.00163 (0.00677) |
0.292 (0.428) |
0.333 (0.472) |
| 7q gain | 173 (33%) | 355 |
0.646 (0.773) |
0.859 (0.97) |
1e-05 (8.42e-05) |
0.0468 (0.103) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.0002 (0.00111) |
0.00439 (0.0159) |
0.0165 (0.0466) |
0.026 (0.0657) |
0.13 (0.229) |
0.717 (0.841) |
| 8p gain | 31 (6%) | 497 |
0.0724 (0.145) |
0.00109 (0.0048) |
0.00044 (0.00222) |
1e-05 (8.42e-05) |
0.0001 (0.000604) |
3e-05 (0.000218) |
4e-05 (0.00028) |
0.00179 (0.00728) |
0.0172 (0.0481) |
0.289 (0.426) |
||
| 6q loss | 128 (24%) | 400 |
0.108 (0.196) |
0.0521 (0.112) |
1e-05 (8.42e-05) |
0.0842 (0.164) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
6e-05 (0.000392) |
1e-05 (8.42e-05) |
0.00172 (0.00712) |
0.0001 (0.000604) |
0.292 (0.428) |
0.031 (0.075) |
| 21q loss | 55 (10%) | 473 |
0.0328 (0.0775) |
0.0894 (0.171) |
0.00069 (0.00326) |
0.0658 (0.135) |
0.0008 (0.00371) |
3e-05 (0.000218) |
0.00081 (0.00374) |
0.00014 (0.000815) |
0.00046 (0.00229) |
0.0049 (0.0174) |
0.774 (0.896) |
0.93 (1.00) |
| 19p gain | 51 (10%) | 477 |
0.332 (0.472) |
0.483 (0.619) |
0.00439 (0.0159) |
0.00094 (0.00424) |
0.0013 (0.00557) |
0.0124 (0.0368) |
0.00572 (0.0193) |
0.00073 (0.00344) |
0.00145 (0.00616) |
0.225 (0.356) |
0.875 (0.985) |
0.711 (0.834) |
| 15q loss | 35 (7%) | 493 |
0.133 (0.234) |
0.331 (0.471) |
0.005 (0.0176) |
0.155 (0.263) |
0.0292 (0.0719) |
0.016 (0.0457) |
7e-05 (0.000448) |
1e-05 (8.42e-05) |
0.00701 (0.0229) |
0.00654 (0.0216) |
0.0628 (0.131) |
0.0989 (0.185) |
| 17q loss | 28 (5%) | 500 |
0.00151 (0.0063) |
0.00052 (0.00256) |
0.0537 (0.115) |
0.0744 (0.148) |
0.155 (0.263) |
0.00273 (0.0107) |
0.0001 (0.000604) |
1e-05 (8.42e-05) |
0.00031 (0.00164) |
0.00496 (0.0175) |
0.532 (0.672) |
0.424 (0.567) |
| xp loss | 45 (9%) | 483 |
0.0261 (0.0657) |
0.0192 (0.0521) |
0.00021 (0.00115) |
0.0228 (0.0589) |
0.551 (0.687) |
0.189 (0.311) |
0.00447 (0.0161) |
0.0214 (0.0564) |
0.129 (0.228) |
0.00101 (0.00453) |
0.0788 (0.155) |
0.243 (0.377) |
| 1p gain | 22 (4%) | 506 |
1 (1.00) |
0.726 (0.85) |
0.00125 (0.00541) |
0.004 (0.0147) |
0.0958 (0.18) |
0.521 (0.66) |
0.0326 (0.0775) |
0.00514 (0.0179) |
5e-05 (0.000343) |
0.0154 (0.0444) |
0.753 (0.878) |
0.315 (0.454) |
| 4p gain | 13 (2%) | 515 |
0.0481 (0.105) |
0.16 (0.27) |
0.038 (0.0863) |
3e-05 (0.000218) |
0.00377 (0.014) |
0.00057 (0.00275) |
0.00552 (0.019) |
0.0979 (0.184) |
||||
| 7p gain | 173 (33%) | 355 |
0.645 (0.772) |
0.858 (0.97) |
1e-05 (8.42e-05) |
0.0643 (0.133) |
1e-05 (8.42e-05) |
1e-05 (8.42e-05) |
0.00029 (0.00155) |
0.00802 (0.0256) |
0.0381 (0.0863) |
0.105 (0.192) |
0.198 (0.323) |
0.846 (0.959) |
| 14q gain | 16 (3%) | 512 |
0.79 (0.906) |
0.573 (0.704) |
0.0861 (0.166) |
0.205 (0.332) |
0.00179 (0.00728) |
0.034 (0.0793) |
0.0392 (0.0884) |
0.00024 (0.00129) |
0.028 (0.0692) |
0.0473 (0.104) |
||
| 19q gain | 57 (11%) | 471 |
0.151 (0.257) |
0.222 (0.352) |
0.0558 (0.119) |
0.00014 (0.000815) |
1e-05 (8.42e-05) |
0.00079 (0.00368) |
0.00091 (0.00414) |
0.00012 (0.000711) |
7e-05 (0.000448) |
0.0782 (0.154) |
0.673 (0.798) |
0.361 (0.503) |
| xp gain | 32 (6%) | 496 |
1 (1.00) |
0.525 (0.664) |
0.0421 (0.0939) |
0.256 (0.39) |
9e-05 (0.000561) |
0.00111 (0.00487) |
0.0355 (0.0817) |
0.00077 (0.00361) |
0.0472 (0.104) |
0.0939 (0.177) |
0.263 (0.396) |
0.916 (1.00) |
| 4q loss | 65 (12%) | 463 |
0.431 (0.571) |
0.782 (0.9) |
0.203 (0.329) |
0.00387 (0.0143) |
0.00033 (0.00174) |
0.0162 (0.0459) |
0.00377 (0.014) |
5e-05 (0.000343) |
0.236 (0.369) |
0.0715 (0.145) |
0.46 (0.598) |
0.0262 (0.0657) |
| 1q gain | 51 (10%) | 477 |
0.468 (0.604) |
0.899 (1.00) |
1e-05 (8.42e-05) |
0.0336 (0.0786) |
0.149 (0.256) |
0.208 (0.335) |
0.00036 (0.00187) |
0.00185 (0.00746) |
2e-05 (0.000155) |
0.15 (0.257) |
0.506 (0.645) |
1 (1.00) |
| 3p gain | 20 (4%) | 508 |
0.0656 (0.135) |
0.434 (0.572) |
0.1 (0.187) |
0.118 (0.212) |
0.107 (0.195) |
0.00012 (0.000711) |
0.00177 (0.00726) |
0.00069 (0.00326) |
0.0001 (0.000604) |
0.00372 (0.0139) |
0.538 (0.676) |
0.655 (0.782) |
| 4q gain | 13 (2%) | 515 |
0.0356 (0.0817) |
0.0846 (0.164) |
0.269 (0.401) |
0.0015 (0.00629) |
0.00372 (0.0139) |
0.00441 (0.0159) |
0.00574 (0.0193) |
0.185 (0.305) |
||||
| 5p gain | 191 (36%) | 337 |
0.78 (0.899) |
0.923 (1.00) |
1e-05 (8.42e-05) |
0.617 (0.75) |
0.0265 (0.0663) |
0.967 (1.00) |
0.0171 (0.0481) |
0.0188 (0.0515) |
0.885 (0.993) |
0.323 (0.464) |
0.0209 (0.0562) |
0.892 (0.998) |
| 10p gain | 16 (3%) | 512 |
0.045 (0.0994) |
0.591 (0.721) |
0.0657 (0.135) |
0.115 (0.209) |
0.00131 (0.00559) |
0.00049 (0.00242) |
0.0342 (0.0794) |
0.0394 (0.0887) |
||||
| 16p gain | 107 (20%) | 421 |
0.341 (0.483) |
0.38 (0.525) |
1e-05 (8.42e-05) |
0.376 (0.521) |
0.0203 (0.0546) |
0.178 (0.294) |
0.00034 (0.00177) |
0.00459 (0.0164) |
0.0509 (0.11) |
0.00905 (0.0287) |
0.257 (0.391) |
0.407 (0.549) |
| 16q gain | 99 (19%) | 429 |
0.346 (0.486) |
0.348 (0.487) |
2e-05 (0.000155) |
0.14 (0.243) |
0.00559 (0.0192) |
0.0918 (0.174) |
0.00067 (0.0032) |
0.0162 (0.0459) |
0.0072 (0.0234) |
0.0804 (0.158) |
0.431 (0.571) |
0.457 (0.596) |
| 17q gain | 33 (6%) | 495 |
0.101 (0.189) |
0.0262 (0.0657) |
0.257 (0.39) |
0.756 (0.88) |
0.117 (0.211) |
0.228 (0.358) |
6e-05 (0.000392) |
0.0015 (0.00629) |
0.0184 (0.0506) |
0.281 (0.417) |
0.00393 (0.0145) |
0.694 (0.816) |
| 5p loss | 8 (2%) | 520 |
0.673 (0.798) |
0.255 (0.39) |
0.00223 (0.00885) |
0.026 (0.0657) |
0.104 (0.192) |
0.0052 (0.0181) |
0.0236 (0.0606) |
0.0274 (0.0681) |
0.482 (0.619) |
0.875 (0.985) |
||
| 10q loss | 89 (17%) | 439 |
0.412 (0.554) |
0.402 (0.548) |
0.0293 (0.072) |
0.0844 (0.164) |
0.816 (0.929) |
0.0213 (0.0564) |
0.269 (0.401) |
0.00193 (0.00769) |
0.00261 (0.0102) |
0.00572 (0.0193) |
0.93 (1.00) |
0.516 (0.656) |
| 11q loss | 23 (4%) | 505 |
0.217 (0.347) |
0.376 (0.521) |
0.0684 (0.139) |
0.143 (0.248) |
0.164 (0.275) |
0.0102 (0.0316) |
0.00624 (0.0208) |
0.00037 (0.00191) |
0.0164 (0.0464) |
0.00976 (0.0306) |
0.381 (0.525) |
0.57 (0.702) |
| 19p loss | 11 (2%) | 517 |
0.674 (0.798) |
0.0642 (0.133) |
0.00022 (0.00119) |
0.00193 (0.00769) |
0.135 (0.236) |
0.0113 (0.0338) |
0.027 (0.0672) |
0.00537 (0.0185) |
0.0573 (0.121) |
0.104 (0.192) |
||
| 13q gain | 22 (4%) | 506 |
0.0108 (0.0327) |
0.0367 (0.0837) |
0.227 (0.357) |
0.431 (0.571) |
0.0488 (0.106) |
0.122 (0.218) |
0.0279 (0.0691) |
0.536 (0.675) |
0.198 (0.323) |
0.343 (0.484) |
||
| 17p gain | 26 (5%) | 502 |
0.023 (0.0595) |
0.00535 (0.0185) |
0.57 (0.702) |
0.888 (0.995) |
0.132 (0.232) |
0.102 (0.189) |
0.00102 (0.00455) |
0.00507 (0.0178) |
0.149 (0.256) |
0.411 (0.554) |
0.063 (0.131) |
0.807 (0.921) |
| 21q gain | 50 (9%) | 478 |
0.286 (0.422) |
0.207 (0.334) |
0.147 (0.255) |
0.00337 (0.0129) |
0.162 (0.272) |
0.0624 (0.131) |
0.00105 (0.00467) |
0.00314 (0.0121) |
0.00802 (0.0256) |
0.119 (0.212) |
0.292 (0.428) |
0.226 (0.356) |
| 4p loss | 72 (14%) | 456 |
0.39 (0.536) |
0.817 (0.929) |
0.397 (0.543) |
0.00457 (0.0164) |
0.0004 (0.00204) |
0.0587 (0.123) |
0.0565 (0.12) |
0.00146 (0.00617) |
0.282 (0.418) |
0.102 (0.189) |
0.0722 (0.145) |
0.044 (0.0978) |
| 5q loss | 7 (1%) | 521 |
0.4 (0.547) |
0.435 (0.573) |
0.0103 (0.0316) |
0.0763 (0.151) |
0.155 (0.263) |
0.00632 (0.021) |
0.049 (0.107) |
0.0317 (0.0761) |
0.484 (0.62) |
0.874 (0.985) |
||
| 8p loss | 137 (26%) | 391 |
0.15 (0.256) |
0.165 (0.276) |
0.0491 (0.107) |
0.477 (0.614) |
0.0724 (0.145) |
0.978 (1.00) |
0.032 (0.0767) |
0.00125 (0.00541) |
0.113 (0.204) |
0.0179 (0.0497) |
0.253 (0.389) |
0.342 (0.483) |
| 10p loss | 68 (13%) | 460 |
0.263 (0.396) |
0.402 (0.548) |
0.183 (0.303) |
0.364 (0.507) |
0.394 (0.541) |
0.0177 (0.0491) |
0.0683 (0.139) |
0.00055 (0.00269) |
0.00739 (0.0238) |
0.0309 (0.0749) |
0.903 (1.00) |
0.418 (0.562) |
| 2p gain | 78 (15%) | 450 |
0.405 (0.548) |
0.267 (0.4) |
0.00046 (0.00229) |
0.449 (0.587) |
0.0724 (0.145) |
0.778 (0.898) |
0.789 (0.906) |
0.0111 (0.0332) |
0.685 (0.809) |
0.0342 (0.0794) |
0.606 (0.738) |
0.366 (0.509) |
| 2q gain | 79 (15%) | 449 |
0.402 (0.548) |
0.268 (0.401) |
0.00122 (0.00532) |
0.623 (0.755) |
0.18 (0.297) |
0.669 (0.798) |
0.798 (0.913) |
0.018 (0.0498) |
0.638 (0.766) |
0.0048 (0.0171) |
0.728 (0.851) |
0.358 (0.5) |
| 5q gain | 210 (40%) | 318 |
0.382 (0.525) |
0.626 (0.757) |
1e-05 (8.42e-05) |
0.689 (0.812) |
0.00742 (0.0238) |
0.329 (0.471) |
0.0885 (0.17) |
0.0523 (0.113) |
0.817 (0.929) |
0.427 (0.569) |
0.0333 (0.0783) |
0.79 (0.906) |
| 10q gain | 12 (2%) | 516 |
0.11 (0.2) |
0.262 (0.396) |
0.0578 (0.122) |
0.0913 (0.174) |
0.00587 (0.0197) |
0.00183 (0.00741) |
0.0135 (0.0397) |
0.172 (0.287) |
||||
| 3q loss | 102 (19%) | 426 |
0.859 (0.97) |
0.22 (0.351) |
0.00021 (0.00115) |
0.353 (0.494) |
0.203 (0.329) |
0.0704 (0.143) |
0.0926 (0.175) |
0.00658 (0.0217) |
0.0138 (0.0403) |
0.938 (1.00) |
0.902 (1.00) |
0.199 (0.324) |
| 9p gain | 14 (3%) | 514 |
0.00189 (0.00759) |
0.235 (0.368) |
0.444 (0.583) |
0.148 (0.255) |
0.566 (0.702) |
0.00982 (0.0307) |
0.449 (0.587) |
0.247 (0.382) |
1 (1.00) |
1 (1.00) |
||
| 9q gain | 13 (2%) | 515 |
0.0215 (0.0565) |
0.687 (0.811) |
0.3 (0.438) |
0.0609 (0.128) |
0.916 (1.00) |
0.0157 (0.045) |
0.286 (0.422) |
0.212 (0.34) |
1 (1.00) |
1 (1.00) |
||
| 15q gain | 26 (5%) | 502 |
1 (1.00) |
0.115 (0.209) |
0.00028 (0.0015) |
0.135 (0.236) |
0.0918 (0.174) |
0.00355 (0.0135) |
0.454 (0.592) |
0.105 (0.192) |
0.636 (0.765) |
0.315 (0.454) |
0.678 (0.802) |
0.285 (0.422) |
| 22q gain | 40 (8%) | 488 |
0.42 (0.564) |
0.22 (0.351) |
0.0853 (0.165) |
0.258 (0.391) |
0.538 (0.676) |
0.293 (0.429) |
0.0826 (0.162) |
0.0159 (0.0456) |
0.0196 (0.0529) |
0.795 (0.911) |
0.914 (1.00) |
0.568 (0.702) |
| xq gain | 31 (6%) | 497 |
0.251 (0.387) |
0.7 (0.822) |
0.0111 (0.0332) |
0.628 (0.757) |
0.0225 (0.0585) |
0.0685 (0.139) |
0.224 (0.354) |
0.1 (0.187) |
0.549 (0.686) |
0.545 (0.682) |
0.43 (0.571) |
0.956 (1.00) |
| 8q loss | 65 (12%) | 463 |
0.131 (0.23) |
0.125 (0.222) |
0.468 (0.604) |
0.00723 (0.0234) |
0.0214 (0.0564) |
0.435 (0.572) |
0.988 (1.00) |
0.199 (0.324) |
0.302 (0.441) |
0.545 (0.682) |
0.739 (0.863) |
0.331 (0.471) |
| 11p loss | 18 (3%) | 510 |
0.571 (0.702) |
0.249 (0.385) |
0.437 (0.574) |
0.104 (0.192) |
0.0659 (0.135) |
0.0276 (0.0684) |
0.171 (0.285) |
0.0344 (0.0797) |
0.382 (0.525) |
0.569 (0.702) |
||
| 16p loss | 10 (2%) | 518 |
0.483 (0.619) |
0.67 (0.798) |
0.126 (0.223) |
0.0493 (0.107) |
0.243 (0.377) |
0.0626 (0.131) |
0.258 (0.391) |
0.0425 (0.0947) |
0.152 (0.259) |
0.314 (0.454) |
||
| 16q loss | 16 (3%) | 512 |
0.019 (0.0517) |
0.417 (0.56) |
0.295 (0.431) |
0.429 (0.571) |
0.0836 (0.163) |
0.0878 (0.169) |
0.189 (0.311) |
0.0317 (0.0761) |
0.15 (0.256) |
0.278 (0.413) |
||
| 6p gain | 11 (2%) | 517 |
0.304 (0.443) |
0.643 (0.77) |
0.217 (0.347) |
0.952 (1.00) |
0.925 (1.00) |
0.983 (1.00) |
0.638 (0.766) |
0.0159 (0.0456) |
0.628 (0.757) |
0.576 (0.706) |
||
| 11p gain | 31 (6%) | 497 |
0.255 (0.39) |
0.672 (0.798) |
0.134 (0.235) |
0.475 (0.612) |
0.0729 (0.146) |
0.509 (0.648) |
0.0345 (0.0797) |
0.237 (0.37) |
0.141 (0.244) |
0.564 (0.7) |
0.541 (0.679) |
0.927 (1.00) |
| 18p gain | 25 (5%) | 503 |
0.403 (0.548) |
0.0768 (0.152) |
0.532 (0.672) |
0.0226 (0.0586) |
0.903 (1.00) |
0.523 (0.663) |
0.221 (0.351) |
0.421 (0.564) |
0.278 (0.413) |
0.345 (0.485) |
0.331 (0.471) |
0.0784 (0.155) |
| 18q gain | 25 (5%) | 503 |
0.405 (0.548) |
0.0751 (0.149) |
0.763 (0.884) |
0.0298 (0.0728) |
0.763 (0.884) |
0.549 (0.686) |
0.47 (0.607) |
0.421 (0.564) |
0.552 (0.687) |
0.342 (0.483) |
0.328 (0.47) |
0.0806 (0.158) |
| 12p loss | 4 (1%) | 524 |
0.00899 (0.0286) |
0.603 (0.736) |
0.467 (0.604) |
0.403 (0.548) |
0.0908 (0.174) |
|||||||
| 20p loss | 8 (2%) | 520 |
0.235 (0.367) |
1 (1.00) |
0.254 (0.39) |
0.495 (0.632) |
0.117 (0.21) |
0.233 (0.365) |
0.0237 (0.0606) |
0.204 (0.33) |
||||
| 6q gain | 9 (2%) | 519 |
0.0548 (0.118) |
0.671 (0.798) |
0.107 (0.196) |
0.809 (0.923) |
0.983 (1.00) |
0.913 (1.00) |
0.806 (0.921) |
0.0562 (0.12) |
0.628 (0.757) |
0.576 (0.706) |
||
| 11q gain | 29 (5%) | 499 |
0.486 (0.621) |
0.906 (1.00) |
0.0853 (0.165) |
0.31 (0.45) |
0.139 (0.242) |
0.829 (0.941) |
0.118 (0.212) |
0.571 (0.702) |
0.563 (0.7) |
0.887 (0.994) |
0.754 (0.879) |
0.759 (0.882) |
| 12q loss | 4 (1%) | 524 |
0.123 (0.219) |
0.214 (0.343) |
0.88 (0.989) |
0.317 (0.455) |
1 (1.00) |
0.568 (0.702) |
0.465 (0.603) |
|||||
| 19q loss | 4 (1%) | 524 |
0.578 (0.706) |
0.263 (0.396) |
0.253 (0.389) |
0.635 (0.765) |
0.511 (0.65) |
0.317 (0.455) |
0.175 (0.29) |
|||||
| 20q loss | 3 (1%) | 525 |
0.464 (0.603) |
0.307 (0.446) |
0.155 (0.263) |
0.175 (0.29) |
0.119 (0.212) |
P value = 0.00125 (Fisher's exact test), Q value = 0.0054
Table S1. Gene #1: '1p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 1P GAIN MUTATED | 1 | 2 | 15 | 4 | 0 | 0 |
| 1P GAIN WILD-TYPE | 60 | 78 | 141 | 78 | 80 | 69 |
Figure S1. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.004 (Fisher's exact test), Q value = 0.015
Table S2. Gene #1: '1p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 1P GAIN MUTATED | 0 | 6 | 5 | 0 |
| 1P GAIN WILD-TYPE | 67 | 64 | 91 | 81 |
Figure S2. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0326 (Fisher's exact test), Q value = 0.078
Table S3. Gene #1: '1p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 1P GAIN MUTATED | 2 | 2 | 4 | 12 | 1 |
| 1P GAIN WILD-TYPE | 79 | 168 | 77 | 141 | 39 |
Figure S3. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00514 (Fisher's exact test), Q value = 0.018
Table S4. Gene #1: '1p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 1P GAIN MUTATED | 1 | 1 | 4 | 11 | 4 | 0 |
| 1P GAIN WILD-TYPE | 116 | 32 | 179 | 121 | 31 | 25 |
Figure S4. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 5e-05 (Fisher's exact test), Q value = 0.00034
Table S5. Gene #1: '1p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 1P GAIN MUTATED | 0 | 2 | 3 | 15 | 2 |
| 1P GAIN WILD-TYPE | 91 | 55 | 183 | 104 | 55 |
Figure S5. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0154 (Fisher's exact test), Q value = 0.044
Table S6. Gene #1: '1p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 1P GAIN MUTATED | 10 | 3 | 9 |
| 1P GAIN WILD-TYPE | 163 | 206 | 119 |
Figure S6. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S7. Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 1Q GAIN MUTATED | 4 | 3 | 36 | 8 | 0 | 0 |
| 1Q GAIN WILD-TYPE | 57 | 77 | 120 | 74 | 80 | 69 |
Figure S7. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0336 (Fisher's exact test), Q value = 0.079
Table S8. Gene #2: '1q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 1Q GAIN MUTATED | 3 | 9 | 11 | 2 |
| 1Q GAIN WILD-TYPE | 64 | 61 | 85 | 79 |
Figure S8. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00036 (Fisher's exact test), Q value = 0.0019
Table S9. Gene #2: '1q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 1Q GAIN MUTATED | 2 | 12 | 6 | 28 | 1 |
| 1Q GAIN WILD-TYPE | 79 | 158 | 75 | 125 | 39 |
Figure S9. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00185 (Fisher's exact test), Q value = 0.0075
Table S10. Gene #2: '1q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 1Q GAIN MUTATED | 4 | 2 | 15 | 22 | 6 | 0 |
| 1Q GAIN WILD-TYPE | 113 | 31 | 168 | 110 | 29 | 25 |
Figure S10. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00015
Table S11. Gene #2: '1q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 1Q GAIN MUTATED | 2 | 8 | 12 | 24 | 3 |
| 1Q GAIN WILD-TYPE | 89 | 49 | 174 | 95 | 54 |
Figure S11. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00046 (Fisher's exact test), Q value = 0.0023
Table S12. Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 2P GAIN MUTATED | 19 | 9 | 30 | 5 | 9 | 6 |
| 2P GAIN WILD-TYPE | 42 | 71 | 126 | 77 | 71 | 63 |
Figure S12. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0111 (Fisher's exact test), Q value = 0.033
Table S13. Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 2P GAIN MUTATED | 13 | 2 | 30 | 29 | 3 | 0 |
| 2P GAIN WILD-TYPE | 104 | 31 | 153 | 103 | 32 | 25 |
Figure S13. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0342 (Fisher's exact test), Q value = 0.079
Table S14. Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 2P GAIN MUTATED | 28 | 39 | 11 |
| 2P GAIN WILD-TYPE | 145 | 170 | 117 |
Figure S14. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00122 (Fisher's exact test), Q value = 0.0053
Table S15. Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 2Q GAIN MUTATED | 19 | 9 | 29 | 6 | 10 | 6 |
| 2Q GAIN WILD-TYPE | 42 | 71 | 127 | 76 | 70 | 63 |
Figure S15. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.018 (Fisher's exact test), Q value = 0.05
Table S16. Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 2Q GAIN MUTATED | 13 | 2 | 32 | 28 | 4 | 0 |
| 2Q GAIN WILD-TYPE | 104 | 31 | 151 | 104 | 31 | 25 |
Figure S16. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0048 (Fisher's exact test), Q value = 0.017
Table S17. Gene #4: '2q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 2Q GAIN MUTATED | 28 | 41 | 9 |
| 2Q GAIN WILD-TYPE | 145 | 168 | 119 |
Figure S17. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00012 (Fisher's exact test), Q value = 0.00071
Table S18. Gene #5: '3p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 3P GAIN MUTATED | 1 | 3 | 11 | 3 |
| 3P GAIN WILD-TYPE | 134 | 109 | 74 | 136 |
Figure S18. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00177 (Fisher's exact test), Q value = 0.0073
Table S19. Gene #5: '3p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 3P GAIN MUTATED | 9 | 2 | 1 | 8 | 0 |
| 3P GAIN WILD-TYPE | 72 | 168 | 80 | 145 | 40 |
Figure S19. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00069 (Fisher's exact test), Q value = 0.0033
Table S20. Gene #5: '3p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 3P GAIN MUTATED | 1 | 2 | 2 | 9 | 2 | 4 |
| 3P GAIN WILD-TYPE | 116 | 31 | 181 | 123 | 33 | 21 |
Figure S20. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-04 (Fisher's exact test), Q value = 6e-04
Table S21. Gene #5: '3p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 3P GAIN MUTATED | 3 | 1 | 1 | 14 | 1 |
| 3P GAIN WILD-TYPE | 88 | 56 | 185 | 105 | 56 |
Figure S21. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00372 (Fisher's exact test), Q value = 0.014
Table S22. Gene #5: '3p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 3P GAIN MUTATED | 8 | 2 | 10 |
| 3P GAIN WILD-TYPE | 165 | 207 | 118 |
Figure S22. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0214 (Fisher's exact test), Q value = 0.056
Table S23. Gene #6: '3q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 3Q GAIN MUTATED | 1 | 7 | 2 |
| 3Q GAIN WILD-TYPE | 30 | 18 | 12 |
Figure S23. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0305 (Fisher's exact test), Q value = 0.074
Table S24. Gene #6: '3q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 3Q GAIN MUTATED | 0 | 2 | 0 | 5 | 0 | 1 | 2 |
| 3Q GAIN WILD-TYPE | 11 | 10 | 4 | 6 | 13 | 8 | 8 |
Figure S24. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0103 (Fisher's exact test), Q value = 0.032
Table S25. Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 3Q GAIN MUTATED | 6 | 7 | 26 | 4 | 14 | 3 |
| 3Q GAIN WILD-TYPE | 55 | 73 | 130 | 78 | 66 | 66 |
Figure S25. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00028
Table S26. Gene #6: '3q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 3Q GAIN MUTATED | 6 | 9 | 19 | 0 |
| 3Q GAIN WILD-TYPE | 61 | 61 | 77 | 81 |
Figure S26. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S27. Gene #6: '3q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 3Q GAIN MUTATED | 16 | 4 | 24 | 4 | 7 | 0 |
| 3Q GAIN WILD-TYPE | 72 | 82 | 66 | 78 | 85 | 33 |
Figure S27. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00015
Table S28. Gene #6: '3q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 3Q GAIN MUTATED | 9 | 12 | 25 | 9 |
| 3Q GAIN WILD-TYPE | 126 | 100 | 60 | 130 |
Figure S28. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00028
Table S29. Gene #6: '3q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 3Q GAIN MUTATED | 15 | 8 | 7 | 29 | 1 |
| 3Q GAIN WILD-TYPE | 66 | 162 | 74 | 124 | 39 |
Figure S29. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00015
Table S30. Gene #6: '3q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 3Q GAIN MUTATED | 8 | 4 | 8 | 29 | 7 | 4 |
| 3Q GAIN WILD-TYPE | 109 | 29 | 175 | 103 | 28 | 21 |
Figure S30. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S31. Gene #6: '3q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 3Q GAIN MUTATED | 7 | 9 | 8 | 31 | 4 |
| 3Q GAIN WILD-TYPE | 84 | 48 | 178 | 88 | 53 |
Figure S31. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S32. Gene #6: '3q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 3Q GAIN MUTATED | 28 | 8 | 23 |
| 3Q GAIN WILD-TYPE | 145 | 201 | 105 |
Figure S32. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00019 (Fisher's exact test), Q value = 0.0011
Table S33. Gene #6: '3q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 3Q GAIN MUTATED | 1 | 0 | 2 | 11 |
| 3Q GAIN WILD-TYPE | 38 | 21 | 42 | 27 |
Figure S33. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0481 (Fisher's exact test), Q value = 0.11
Table S34. Gene #7: '4p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 4P GAIN MUTATED | 2 | 2 | 4 | 0 | 0 | 5 |
| 4P GAIN WILD-TYPE | 59 | 78 | 152 | 82 | 80 | 64 |
Figure S34. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.038 (Fisher's exact test), Q value = 0.086
Table S35. Gene #7: '4p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 4P GAIN MUTATED | 3 | 1 | 5 | 0 | 0 | 0 |
| 4P GAIN WILD-TYPE | 85 | 85 | 85 | 82 | 92 | 33 |
Figure S35. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00022
Table S36. Gene #7: '4p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 4P GAIN MUTATED | 0 | 2 | 7 | 0 |
| 4P GAIN WILD-TYPE | 135 | 110 | 78 | 139 |
Figure S36. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00377 (Fisher's exact test), Q value = 0.014
Table S37. Gene #7: '4p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 4P GAIN MUTATED | 5 | 0 | 3 | 2 | 2 |
| 4P GAIN WILD-TYPE | 76 | 170 | 78 | 151 | 38 |
Figure S37. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00057 (Fisher's exact test), Q value = 0.0027
Table S38. Gene #7: '4p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 4P GAIN MUTATED | 3 | 0 | 0 | 5 | 0 | 4 |
| 4P GAIN WILD-TYPE | 114 | 33 | 183 | 127 | 35 | 21 |
Figure S38. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00552 (Fisher's exact test), Q value = 0.019
Table S39. Gene #7: '4p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 4P GAIN MUTATED | 2 | 2 | 0 | 7 | 2 |
| 4P GAIN WILD-TYPE | 89 | 55 | 186 | 112 | 55 |
Figure S39. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0356 (Fisher's exact test), Q value = 0.082
Table S40. Gene #8: '4q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 4Q GAIN MUTATED | 2 | 1 | 5 | 0 | 0 | 5 |
| 4Q GAIN WILD-TYPE | 59 | 79 | 151 | 82 | 80 | 64 |
Figure S40. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0015 (Fisher's exact test), Q value = 0.0063
Table S41. Gene #8: '4q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 4Q GAIN MUTATED | 1 | 2 | 6 | 0 |
| 4Q GAIN WILD-TYPE | 134 | 110 | 79 | 139 |
Figure S41. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00372 (Fisher's exact test), Q value = 0.014
Table S42. Gene #8: '4q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 4Q GAIN MUTATED | 5 | 0 | 3 | 2 | 2 |
| 4Q GAIN WILD-TYPE | 76 | 170 | 78 | 151 | 38 |
Figure S42. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00441 (Fisher's exact test), Q value = 0.016
Table S43. Gene #8: '4q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 4Q GAIN MUTATED | 3 | 0 | 1 | 4 | 0 | 4 |
| 4Q GAIN WILD-TYPE | 114 | 33 | 182 | 128 | 35 | 21 |
Figure S43. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00574 (Fisher's exact test), Q value = 0.019
Table S44. Gene #8: '4q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 4Q GAIN MUTATED | 2 | 2 | 0 | 7 | 2 |
| 4Q GAIN WILD-TYPE | 89 | 55 | 186 | 112 | 55 |
Figure S44. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S45. Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 5P GAIN MUTATED | 44 | 35 | 52 | 21 | 26 | 13 |
| 5P GAIN WILD-TYPE | 17 | 45 | 104 | 61 | 54 | 56 |
Figure S45. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0265 (Fisher's exact test), Q value = 0.066
Table S46. Gene #9: '5p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 5P GAIN MUTATED | 32 | 19 | 39 | 36 | 36 | 10 |
| 5P GAIN WILD-TYPE | 56 | 67 | 51 | 46 | 56 | 23 |
Figure S46. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0171 (Fisher's exact test), Q value = 0.048
Table S47. Gene #9: '5p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 5P GAIN MUTATED | 21 | 57 | 25 | 71 | 15 |
| 5P GAIN WILD-TYPE | 60 | 113 | 56 | 82 | 25 |
Figure S47. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0188 (Fisher's exact test), Q value = 0.052
Table S48. Gene #9: '5p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 5P GAIN MUTATED | 43 | 7 | 61 | 60 | 14 | 4 |
| 5P GAIN WILD-TYPE | 74 | 26 | 122 | 72 | 21 | 21 |
Figure S48. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0209 (Fisher's exact test), Q value = 0.056
Table S49. Gene #9: '5p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 5P GAIN MUTATED | 13 | 4 | 16 | 22 |
| 5P GAIN WILD-TYPE | 26 | 17 | 28 | 16 |
Figure S49. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S50. Gene #10: '5q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 5Q GAIN MUTATED | 47 | 35 | 55 | 30 | 29 | 14 |
| 5Q GAIN WILD-TYPE | 14 | 45 | 101 | 52 | 51 | 55 |
Figure S50. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00742 (Fisher's exact test), Q value = 0.024
Table S51. Gene #10: '5q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 5Q GAIN MUTATED | 36 | 20 | 37 | 42 | 41 | 14 |
| 5Q GAIN WILD-TYPE | 52 | 66 | 53 | 40 | 51 | 19 |
Figure S51. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0333 (Fisher's exact test), Q value = 0.078
Table S52. Gene #10: '5q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 5Q GAIN MUTATED | 12 | 4 | 17 | 21 |
| 5Q GAIN WILD-TYPE | 27 | 17 | 27 | 17 |
Figure S52. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0159 (Fisher's exact test), Q value = 0.046
Table S53. Gene #11: '6p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 6P GAIN MUTATED | 2 | 9 | 0 |
| 6P GAIN WILD-TYPE | 171 | 200 | 128 |
Figure S53. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S54. Gene #13: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 7P GAIN MUTATED | 37 | 34 | 54 | 11 | 23 | 14 |
| 7P GAIN WILD-TYPE | 24 | 46 | 102 | 71 | 57 | 55 |
Figure S54. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S55. Gene #13: '7p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 7P GAIN MUTATED | 32 | 22 | 51 | 23 | 22 | 5 |
| 7P GAIN WILD-TYPE | 56 | 64 | 39 | 59 | 70 | 28 |
Figure S55. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S56. Gene #13: '7p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 7P GAIN MUTATED | 34 | 49 | 41 | 31 |
| 7P GAIN WILD-TYPE | 101 | 63 | 44 | 108 |
Figure S56. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00029 (Fisher's exact test), Q value = 0.0015
Table S57. Gene #13: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 7P GAIN MUTATED | 23 | 38 | 27 | 71 | 12 |
| 7P GAIN WILD-TYPE | 58 | 132 | 54 | 82 | 28 |
Figure S57. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00802 (Fisher's exact test), Q value = 0.026
Table S58. Gene #13: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 7P GAIN MUTATED | 38 | 9 | 46 | 60 | 12 | 6 |
| 7P GAIN WILD-TYPE | 79 | 24 | 137 | 72 | 23 | 19 |
Figure S58. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0381 (Fisher's exact test), Q value = 0.086
Table S59. Gene #13: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 7P GAIN MUTATED | 26 | 26 | 56 | 48 | 14 |
| 7P GAIN WILD-TYPE | 65 | 31 | 130 | 71 | 43 |
Figure S59. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S60. Gene #14: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 7Q GAIN MUTATED | 39 | 34 | 54 | 11 | 22 | 13 |
| 7Q GAIN WILD-TYPE | 22 | 46 | 102 | 71 | 58 | 56 |
Figure S60. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0468 (Fisher's exact test), Q value = 0.1
Table S61. Gene #14: '7q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 7Q GAIN MUTATED | 12 | 23 | 35 | 20 |
| 7Q GAIN WILD-TYPE | 55 | 47 | 61 | 61 |
Figure S61. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S62. Gene #14: '7q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 7Q GAIN MUTATED | 32 | 21 | 51 | 24 | 23 | 4 |
| 7Q GAIN WILD-TYPE | 56 | 65 | 39 | 58 | 69 | 29 |
Figure S62. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S63. Gene #14: '7q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 7Q GAIN MUTATED | 35 | 50 | 41 | 29 |
| 7Q GAIN WILD-TYPE | 100 | 62 | 44 | 110 |
Figure S63. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 2e-04 (Fisher's exact test), Q value = 0.0011
Table S64. Gene #14: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 7Q GAIN MUTATED | 25 | 37 | 27 | 70 | 12 |
| 7Q GAIN WILD-TYPE | 56 | 133 | 54 | 83 | 28 |
Figure S64. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00439 (Fisher's exact test), Q value = 0.016
Table S65. Gene #14: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 7Q GAIN MUTATED | 37 | 11 | 44 | 60 | 13 | 6 |
| 7Q GAIN WILD-TYPE | 80 | 22 | 139 | 72 | 22 | 19 |
Figure S65. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0165 (Fisher's exact test), Q value = 0.047
Table S66. Gene #14: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 7Q GAIN MUTATED | 26 | 26 | 54 | 50 | 14 |
| 7Q GAIN WILD-TYPE | 65 | 31 | 132 | 69 | 43 |
Figure S66. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.026 (Fisher's exact test), Q value = 0.066
Table S67. Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 7Q GAIN MUTATED | 60 | 57 | 53 |
| 7Q GAIN WILD-TYPE | 113 | 152 | 75 |
Figure S67. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00109 (Fisher's exact test), Q value = 0.0048
Table S68. Gene #15: '8p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 8P GAIN MUTATED | 2 | 4 | 15 | 1 |
| 8P GAIN WILD-TYPE | 65 | 66 | 81 | 80 |
Figure S68. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00044 (Fisher's exact test), Q value = 0.0022
Table S69. Gene #15: '8p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 8P GAIN MUTATED | 3 | 2 | 16 | 4 | 4 | 0 |
| 8P GAIN WILD-TYPE | 85 | 84 | 74 | 78 | 88 | 33 |
Figure S69. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S70. Gene #15: '8p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 8P GAIN MUTATED | 1 | 18 | 7 | 3 |
| 8P GAIN WILD-TYPE | 134 | 94 | 78 | 136 |
Figure S70. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-04 (Fisher's exact test), Q value = 6e-04
Table S71. Gene #15: '8p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 8P GAIN MUTATED | 4 | 1 | 5 | 19 | 2 |
| 8P GAIN WILD-TYPE | 77 | 169 | 76 | 134 | 38 |
Figure S71. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00022
Table S72. Gene #15: '8p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 8P GAIN MUTATED | 6 | 2 | 1 | 19 | 2 | 1 |
| 8P GAIN WILD-TYPE | 111 | 31 | 182 | 113 | 33 | 24 |
Figure S72. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00028
Table S73. Gene #15: '8p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 8P GAIN MUTATED | 4 | 4 | 2 | 18 | 3 |
| 8P GAIN WILD-TYPE | 87 | 53 | 184 | 101 | 54 |
Figure S73. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00179 (Fisher's exact test), Q value = 0.0073
Table S74. Gene #15: '8p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 8P GAIN MUTATED | 15 | 4 | 12 |
| 8P GAIN WILD-TYPE | 158 | 205 | 116 |
Figure S74. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0172 (Fisher's exact test), Q value = 0.048
Table S75. Gene #15: '8p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 8P GAIN MUTATED | 1 | 0 | 0 | 5 |
| 8P GAIN WILD-TYPE | 38 | 21 | 44 | 33 |
Figure S75. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S76. Gene #16: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 8Q GAIN MUTATED | 5 | 8 | 37 | 2 | 8 | 1 |
| 8Q GAIN WILD-TYPE | 56 | 72 | 119 | 80 | 72 | 68 |
Figure S76. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S77. Gene #16: '8q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 8Q GAIN MUTATED | 2 | 13 | 23 | 2 |
| 8Q GAIN WILD-TYPE | 65 | 57 | 73 | 79 |
Figure S77. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S78. Gene #16: '8q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 8Q GAIN MUTATED | 9 | 4 | 29 | 6 | 8 | 1 |
| 8Q GAIN WILD-TYPE | 79 | 82 | 61 | 76 | 84 | 32 |
Figure S78. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S79. Gene #16: '8q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 8Q GAIN MUTATED | 5 | 29 | 16 | 7 |
| 8Q GAIN WILD-TYPE | 130 | 83 | 69 | 132 |
Figure S79. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S80. Gene #16: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 8Q GAIN MUTATED | 4 | 4 | 7 | 42 | 3 |
| 8Q GAIN WILD-TYPE | 77 | 166 | 74 | 111 | 37 |
Figure S80. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S81. Gene #16: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 8Q GAIN MUTATED | 8 | 2 | 4 | 41 | 4 | 1 |
| 8Q GAIN WILD-TYPE | 109 | 31 | 179 | 91 | 31 | 24 |
Figure S81. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S82. Gene #16: '8q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 8Q GAIN MUTATED | 7 | 10 | 7 | 30 | 5 |
| 8Q GAIN WILD-TYPE | 84 | 47 | 179 | 89 | 52 |
Figure S82. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00039
Table S83. Gene #16: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 8Q GAIN MUTATED | 29 | 9 | 21 |
| 8Q GAIN WILD-TYPE | 144 | 200 | 107 |
Figure S83. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00015
Table S84. Gene #16: '8q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 8Q GAIN MUTATED | 3 | 0 | 0 | 11 |
| 8Q GAIN WILD-TYPE | 36 | 21 | 44 | 27 |
Figure S84. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00189 (Fisher's exact test), Q value = 0.0076
Table S85. Gene #17: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 9P GAIN MUTATED | 1 | 2 | 1 | 0 | 3 | 7 |
| 9P GAIN WILD-TYPE | 60 | 78 | 155 | 82 | 77 | 62 |
Figure S85. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00982 (Fisher's exact test), Q value = 0.031
Table S86. Gene #17: '9p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 9P GAIN MUTATED | 0 | 0 | 7 | 2 | 2 | 3 |
| 9P GAIN WILD-TYPE | 117 | 33 | 176 | 130 | 33 | 22 |
Figure S86. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0215 (Fisher's exact test), Q value = 0.056
Table S87. Gene #18: '9q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 9Q GAIN MUTATED | 1 | 3 | 1 | 0 | 3 | 5 |
| 9Q GAIN WILD-TYPE | 60 | 77 | 155 | 82 | 77 | 64 |
Figure S87. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0157 (Fisher's exact test), Q value = 0.045
Table S88. Gene #18: '9q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 9Q GAIN MUTATED | 0 | 0 | 4 | 4 | 2 | 3 |
| 9Q GAIN WILD-TYPE | 117 | 33 | 179 | 128 | 33 | 22 |
Figure S88. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.045 (Fisher's exact test), Q value = 0.099
Table S89. Gene #19: '10p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 10P GAIN MUTATED | 3 | 1 | 9 | 0 | 3 | 0 |
| 10P GAIN WILD-TYPE | 58 | 79 | 147 | 82 | 77 | 69 |
Figure S89. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00131 (Fisher's exact test), Q value = 0.0056
Table S90. Gene #19: '10p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 10P GAIN MUTATED | 3 | 0 | 2 | 11 | 0 |
| 10P GAIN WILD-TYPE | 78 | 170 | 79 | 142 | 40 |
Figure S90. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00049 (Fisher's exact test), Q value = 0.0024
Table S91. Gene #19: '10p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 10P GAIN MUTATED | 2 | 1 | 0 | 11 | 2 | 0 |
| 10P GAIN WILD-TYPE | 115 | 32 | 183 | 121 | 33 | 25 |
Figure S91. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0342 (Fisher's exact test), Q value = 0.079
Table S92. Gene #19: '10p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 10P GAIN MUTATED | 3 | 1 | 2 | 9 | 1 |
| 10P GAIN WILD-TYPE | 88 | 56 | 184 | 110 | 56 |
Figure S92. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0394 (Fisher's exact test), Q value = 0.089
Table S93. Gene #19: '10p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 10P GAIN MUTATED | 7 | 2 | 7 |
| 10P GAIN WILD-TYPE | 166 | 207 | 121 |
Figure S93. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00587 (Fisher's exact test), Q value = 0.02
Table S94. Gene #20: '10q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 10Q GAIN MUTATED | 2 | 0 | 1 | 9 | 0 |
| 10Q GAIN WILD-TYPE | 79 | 170 | 80 | 144 | 40 |
Figure S94. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00183 (Fisher's exact test), Q value = 0.0074
Table S95. Gene #20: '10q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 10Q GAIN MUTATED | 1 | 1 | 0 | 9 | 1 | 0 |
| 10Q GAIN WILD-TYPE | 116 | 32 | 183 | 123 | 34 | 25 |
Figure S95. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0135 (Fisher's exact test), Q value = 0.04
Table S96. Gene #20: '10q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 10Q GAIN MUTATED | 1 | 1 | 1 | 8 | 1 |
| 10Q GAIN WILD-TYPE | 90 | 56 | 185 | 111 | 56 |
Figure S96. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0345 (Fisher's exact test), Q value = 0.08
Table S97. Gene #21: '11p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 11P GAIN MUTATED | 7 | 3 | 7 | 12 | 2 |
| 11P GAIN WILD-TYPE | 74 | 167 | 74 | 141 | 38 |
Figure S97. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0219 (Fisher's exact test), Q value = 0.057
Table S98. Gene #23: '12p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 12P GAIN MUTATED | 3 | 10 | 2 |
| 12P GAIN WILD-TYPE | 28 | 15 | 12 |
Figure S98. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0328 (Fisher's exact test), Q value = 0.078
Table S99. Gene #23: '12p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 12P GAIN MUTATED | 0 | 4 | 0 | 6 | 1 | 2 | 2 |
| 12P GAIN WILD-TYPE | 11 | 8 | 4 | 5 | 12 | 7 | 8 |
Figure S99. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00028
Table S100. Gene #23: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 12P GAIN MUTATED | 20 | 25 | 40 | 7 | 23 | 6 |
| 12P GAIN WILD-TYPE | 41 | 55 | 116 | 75 | 57 | 63 |
Figure S100. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.00092
Table S101. Gene #23: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 12P GAIN MUTATED | 12 | 21 | 35 | 8 |
| 12P GAIN WILD-TYPE | 55 | 49 | 61 | 73 |
Figure S101. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S102. Gene #23: '12p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 12P GAIN MUTATED | 16 | 3 | 47 | 20 | 19 | 2 |
| 12P GAIN WILD-TYPE | 72 | 83 | 43 | 62 | 73 | 31 |
Figure S102. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00022
Table S103. Gene #23: '12p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 12P GAIN MUTATED | 21 | 37 | 31 | 18 |
| 12P GAIN WILD-TYPE | 114 | 75 | 54 | 121 |
Figure S103. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S104. Gene #23: '12p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 12P GAIN MUTATED | 18 | 14 | 15 | 67 | 6 |
| 12P GAIN WILD-TYPE | 63 | 156 | 66 | 86 | 34 |
Figure S104. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S105. Gene #23: '12p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 12P GAIN MUTATED | 22 | 5 | 19 | 58 | 11 | 5 |
| 12P GAIN WILD-TYPE | 95 | 28 | 164 | 74 | 24 | 20 |
Figure S105. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S106. Gene #23: '12p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 12P GAIN MUTATED | 16 | 18 | 22 | 49 | 14 |
| 12P GAIN WILD-TYPE | 75 | 39 | 164 | 70 | 43 |
Figure S106. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S107. Gene #23: '12p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 12P GAIN MUTATED | 47 | 26 | 46 |
| 12P GAIN WILD-TYPE | 126 | 183 | 82 |
Figure S107. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00176 (Fisher's exact test), Q value = 0.0073
Table S108. Gene #23: '12p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 12P GAIN MUTATED | 5 | 3 | 4 | 16 |
| 12P GAIN WILD-TYPE | 34 | 18 | 40 | 22 |
Figure S108. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0211 (Fisher's exact test), Q value = 0.056
Table S109. Gene #24: '12q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 12Q GAIN MUTATED | 3 | 10 | 2 |
| 12Q GAIN WILD-TYPE | 28 | 15 | 12 |
Figure S109. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0329 (Fisher's exact test), Q value = 0.078
Table S110. Gene #24: '12q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 12Q GAIN MUTATED | 0 | 4 | 0 | 6 | 1 | 2 | 2 |
| 12Q GAIN WILD-TYPE | 11 | 8 | 4 | 5 | 12 | 7 | 8 |
Figure S110. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00022
Table S111. Gene #24: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 12Q GAIN MUTATED | 20 | 24 | 41 | 7 | 23 | 7 |
| 12Q GAIN WILD-TYPE | 41 | 56 | 115 | 75 | 57 | 62 |
Figure S111. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00081
Table S112. Gene #24: '12q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 12Q GAIN MUTATED | 12 | 20 | 36 | 8 |
| 12Q GAIN WILD-TYPE | 55 | 50 | 60 | 73 |
Figure S112. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S113. Gene #24: '12q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 12Q GAIN MUTATED | 16 | 3 | 49 | 20 | 18 | 2 |
| 12Q GAIN WILD-TYPE | 72 | 83 | 41 | 62 | 74 | 31 |
Figure S113. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S114. Gene #24: '12q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 12Q GAIN MUTATED | 21 | 38 | 31 | 18 |
| 12Q GAIN WILD-TYPE | 114 | 74 | 54 | 121 |
Figure S114. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S115. Gene #24: '12q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 12Q GAIN MUTATED | 19 | 14 | 14 | 68 | 6 |
| 12Q GAIN WILD-TYPE | 62 | 156 | 67 | 85 | 34 |
Figure S115. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S116. Gene #24: '12q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 12Q GAIN MUTATED | 22 | 5 | 19 | 59 | 11 | 5 |
| 12Q GAIN WILD-TYPE | 95 | 28 | 164 | 73 | 24 | 20 |
Figure S116. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S117. Gene #24: '12q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 12Q GAIN MUTATED | 15 | 19 | 22 | 49 | 15 |
| 12Q GAIN WILD-TYPE | 76 | 38 | 164 | 70 | 42 |
Figure S117. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S118. Gene #24: '12q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 12Q GAIN MUTATED | 47 | 26 | 47 |
| 12Q GAIN WILD-TYPE | 126 | 183 | 81 |
Figure S118. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00236 (Fisher's exact test), Q value = 0.0093
Table S119. Gene #24: '12q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 12Q GAIN MUTATED | 6 | 3 | 4 | 16 |
| 12Q GAIN WILD-TYPE | 33 | 18 | 40 | 22 |
Figure S119. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0108 (Fisher's exact test), Q value = 0.033
Table S120. Gene #25: '13q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 13Q GAIN MUTATED | 4 | 8 | 1 | 4 | 3 | 2 |
| 13Q GAIN WILD-TYPE | 57 | 72 | 155 | 78 | 77 | 67 |
Figure S120. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0367 (Fisher's exact test), Q value = 0.084
Table S121. Gene #25: '13q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 13Q GAIN MUTATED | 2 | 1 | 11 | 4 |
| 13Q GAIN WILD-TYPE | 65 | 69 | 85 | 77 |
Figure S121. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0488 (Fisher's exact test), Q value = 0.11
Table S122. Gene #25: '13q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 13Q GAIN MUTATED | 4 | 3 | 8 | 5 | 2 |
| 13Q GAIN WILD-TYPE | 77 | 167 | 73 | 148 | 38 |
Figure S122. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0279 (Fisher's exact test), Q value = 0.069
Table S123. Gene #25: '13q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 13Q GAIN MUTATED | 4 | 0 | 6 | 4 | 7 |
| 13Q GAIN WILD-TYPE | 87 | 57 | 180 | 115 | 50 |
Figure S123. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00179 (Fisher's exact test), Q value = 0.0073
Table S124. Gene #26: '14q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 14Q GAIN MUTATED | 5 | 0 | 7 | 1 | 0 | 0 |
| 14Q GAIN WILD-TYPE | 83 | 86 | 83 | 81 | 92 | 33 |
Figure S124. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.034 (Fisher's exact test), Q value = 0.079
Table S125. Gene #26: '14q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 14Q GAIN MUTATED | 1 | 4 | 6 | 2 |
| 14Q GAIN WILD-TYPE | 134 | 108 | 79 | 137 |
Figure S125. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0392 (Fisher's exact test), Q value = 0.088
Table S126. Gene #26: '14q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 14Q GAIN MUTATED | 6 | 1 | 3 | 5 | 1 |
| 14Q GAIN WILD-TYPE | 75 | 169 | 78 | 148 | 39 |
Figure S126. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00024 (Fisher's exact test), Q value = 0.0013
Table S127. Gene #26: '14q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 14Q GAIN MUTATED | 3 | 0 | 1 | 7 | 0 | 5 |
| 14Q GAIN WILD-TYPE | 114 | 33 | 182 | 125 | 35 | 20 |
Figure S127. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.028 (Fisher's exact test), Q value = 0.069
Table S128. Gene #26: '14q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 14Q GAIN MUTATED | 2 | 3 | 1 | 7 | 2 |
| 14Q GAIN WILD-TYPE | 89 | 54 | 185 | 112 | 55 |
Figure S128. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0473 (Fisher's exact test), Q value = 0.1
Table S129. Gene #26: '14q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 14Q GAIN MUTATED | 6 | 2 | 7 |
| 14Q GAIN WILD-TYPE | 167 | 207 | 121 |
Figure S129. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00028 (Fisher's exact test), Q value = 0.0015
Table S130. Gene #27: '15q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 15Q GAIN MUTATED | 7 | 4 | 3 | 0 | 10 | 2 |
| 15Q GAIN WILD-TYPE | 54 | 76 | 153 | 82 | 70 | 67 |
Figure S130. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00355 (Fisher's exact test), Q value = 0.013
Table S131. Gene #27: '15q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 15Q GAIN MUTATED | 0 | 7 | 6 | 9 |
| 15Q GAIN WILD-TYPE | 135 | 105 | 79 | 130 |
Figure S131. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S132. Gene #28: '16p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 16P GAIN MUTATED | 25 | 21 | 30 | 6 | 19 | 6 |
| 16P GAIN WILD-TYPE | 36 | 59 | 126 | 76 | 61 | 63 |
Figure S132. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0203 (Fisher's exact test), Q value = 0.055
Table S133. Gene #28: '16p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 16P GAIN MUTATED | 23 | 10 | 23 | 22 | 13 | 4 |
| 16P GAIN WILD-TYPE | 65 | 76 | 67 | 60 | 79 | 29 |
Figure S133. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0018
Table S134. Gene #28: '16p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 16P GAIN MUTATED | 22 | 18 | 16 | 44 | 7 |
| 16P GAIN WILD-TYPE | 59 | 152 | 65 | 109 | 33 |
Figure S134. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00459 (Fisher's exact test), Q value = 0.016
Table S135. Gene #28: '16p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 16P GAIN MUTATED | 26 | 13 | 23 | 34 | 6 | 5 |
| 16P GAIN WILD-TYPE | 91 | 20 | 160 | 98 | 29 | 20 |
Figure S135. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00905 (Fisher's exact test), Q value = 0.029
Table S136. Gene #28: '16p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 16P GAIN MUTATED | 32 | 35 | 39 |
| 16P GAIN WILD-TYPE | 141 | 174 | 89 |
Figure S136. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00015
Table S137. Gene #29: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 16Q GAIN MUTATED | 22 | 21 | 26 | 5 | 19 | 6 |
| 16Q GAIN WILD-TYPE | 39 | 59 | 130 | 77 | 61 | 63 |
Figure S137. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00559 (Fisher's exact test), Q value = 0.019
Table S138. Gene #29: '16q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 16Q GAIN MUTATED | 23 | 7 | 23 | 18 | 12 | 4 |
| 16Q GAIN WILD-TYPE | 65 | 79 | 67 | 64 | 80 | 29 |
Figure S138. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00067 (Fisher's exact test), Q value = 0.0032
Table S139. Gene #29: '16q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 16Q GAIN MUTATED | 19 | 16 | 15 | 42 | 7 |
| 16Q GAIN WILD-TYPE | 62 | 154 | 66 | 111 | 33 |
Figure S139. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0162 (Fisher's exact test), Q value = 0.046
Table S140. Gene #29: '16q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 16Q GAIN MUTATED | 23 | 11 | 22 | 33 | 6 | 4 |
| 16Q GAIN WILD-TYPE | 94 | 22 | 161 | 99 | 29 | 21 |
Figure S140. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0072 (Fisher's exact test), Q value = 0.023
Table S141. Gene #29: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 16Q GAIN MUTATED | 18 | 17 | 22 | 30 | 11 |
| 16Q GAIN WILD-TYPE | 73 | 40 | 164 | 89 | 46 |
Figure S141. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.023 (Fisher's exact test), Q value = 0.059
Table S142. Gene #30: '17p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 17P GAIN MUTATED | 1 | 0 | 3 |
| 17P GAIN WILD-TYPE | 30 | 25 | 11 |
Figure S142. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00535 (Fisher's exact test), Q value = 0.019
Table S143. Gene #30: '17p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 17P GAIN MUTATED | 0 | 0 | 2 | 0 | 0 | 1 | 1 |
| 17P GAIN WILD-TYPE | 11 | 12 | 2 | 11 | 13 | 8 | 9 |
Figure S143. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00102 (Fisher's exact test), Q value = 0.0046
Table S144. Gene #30: '17p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 17P GAIN MUTATED | 11 | 4 | 1 | 10 | 0 |
| 17P GAIN WILD-TYPE | 70 | 166 | 80 | 143 | 40 |
Figure S144. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00507 (Fisher's exact test), Q value = 0.018
Table S145. Gene #30: '17p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 17P GAIN MUTATED | 2 | 6 | 5 | 10 | 2 | 1 |
| 17P GAIN WILD-TYPE | 115 | 27 | 178 | 122 | 33 | 24 |
Figure S145. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0262 (Fisher's exact test), Q value = 0.066
Table S146. Gene #31: '17q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 17Q GAIN MUTATED | 0 | 0 | 2 | 1 | 0 | 1 | 1 |
| 17Q GAIN WILD-TYPE | 11 | 12 | 2 | 10 | 13 | 8 | 9 |
Figure S146. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00039
Table S147. Gene #31: '17q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 17Q GAIN MUTATED | 13 | 5 | 1 | 14 | 0 |
| 17Q GAIN WILD-TYPE | 68 | 165 | 80 | 139 | 40 |
Figure S147. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0015 (Fisher's exact test), Q value = 0.0063
Table S148. Gene #31: '17q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 17Q GAIN MUTATED | 3 | 7 | 6 | 13 | 3 | 1 |
| 17Q GAIN WILD-TYPE | 114 | 26 | 177 | 119 | 32 | 24 |
Figure S148. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0184 (Fisher's exact test), Q value = 0.051
Table S149. Gene #31: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 17Q GAIN MUTATED | 7 | 2 | 6 | 15 | 2 |
| 17Q GAIN WILD-TYPE | 84 | 55 | 180 | 104 | 55 |
Figure S149. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00393 (Fisher's exact test), Q value = 0.015
Table S150. Gene #31: '17q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 17Q GAIN MUTATED | 1 | 0 | 0 | 6 |
| 17Q GAIN WILD-TYPE | 38 | 21 | 44 | 32 |
Figure S150. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0226 (Fisher's exact test), Q value = 0.059
Table S151. Gene #32: '18p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 18P GAIN MUTATED | 7 | 0 | 3 | 4 |
| 18P GAIN WILD-TYPE | 60 | 70 | 93 | 77 |
Figure S151. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0298 (Fisher's exact test), Q value = 0.073
Table S152. Gene #33: '18q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 18Q GAIN MUTATED | 7 | 0 | 4 | 4 |
| 18Q GAIN WILD-TYPE | 60 | 70 | 92 | 77 |
Figure S152. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00439 (Fisher's exact test), Q value = 0.016
Table S153. Gene #34: '19p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 19P GAIN MUTATED | 9 | 9 | 17 | 0 | 10 | 6 |
| 19P GAIN WILD-TYPE | 52 | 71 | 139 | 82 | 70 | 63 |
Figure S153. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00094 (Fisher's exact test), Q value = 0.0042
Table S154. Gene #34: '19p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 19P GAIN MUTATED | 9 | 3 | 19 | 3 |
| 19P GAIN WILD-TYPE | 58 | 67 | 77 | 78 |
Figure S154. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0013 (Fisher's exact test), Q value = 0.0056
Table S155. Gene #34: '19p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 19P GAIN MUTATED | 13 | 3 | 17 | 7 | 6 | 0 |
| 19P GAIN WILD-TYPE | 75 | 83 | 73 | 75 | 86 | 33 |
Figure S155. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0124 (Fisher's exact test), Q value = 0.037
Table S156. Gene #34: '19p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 19P GAIN MUTATED | 6 | 17 | 12 | 11 |
| 19P GAIN WILD-TYPE | 129 | 95 | 73 | 128 |
Figure S156. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00572 (Fisher's exact test), Q value = 0.019
Table S157. Gene #34: '19p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 19P GAIN MUTATED | 11 | 6 | 9 | 22 | 3 |
| 19P GAIN WILD-TYPE | 70 | 164 | 72 | 131 | 37 |
Figure S157. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00073 (Fisher's exact test), Q value = 0.0034
Table S158. Gene #34: '19p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 19P GAIN MUTATED | 10 | 2 | 8 | 24 | 2 | 5 |
| 19P GAIN WILD-TYPE | 107 | 31 | 175 | 108 | 33 | 20 |
Figure S158. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00145 (Fisher's exact test), Q value = 0.0062
Table S159. Gene #34: '19p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 19P GAIN MUTATED | 8 | 7 | 7 | 19 | 9 |
| 19P GAIN WILD-TYPE | 83 | 50 | 179 | 100 | 48 |
Figure S159. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00081
Table S160. Gene #35: '19q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 19Q GAIN MUTATED | 9 | 3 | 22 | 3 |
| 19Q GAIN WILD-TYPE | 58 | 67 | 74 | 78 |
Figure S160. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S161. Gene #35: '19q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 19Q GAIN MUTATED | 13 | 3 | 23 | 7 | 6 | 0 |
| 19Q GAIN WILD-TYPE | 75 | 83 | 67 | 75 | 86 | 33 |
Figure S161. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00079 (Fisher's exact test), Q value = 0.0037
Table S162. Gene #35: '19q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 19Q GAIN MUTATED | 6 | 20 | 15 | 11 |
| 19Q GAIN WILD-TYPE | 129 | 92 | 70 | 128 |
Figure S162. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00091 (Fisher's exact test), Q value = 0.0041
Table S163. Gene #35: '19q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 19Q GAIN MUTATED | 11 | 6 | 9 | 26 | 4 |
| 19Q GAIN WILD-TYPE | 70 | 164 | 72 | 127 | 36 |
Figure S163. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00012 (Fisher's exact test), Q value = 0.00071
Table S164. Gene #35: '19q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 19Q GAIN MUTATED | 11 | 2 | 8 | 28 | 2 | 5 |
| 19Q GAIN WILD-TYPE | 106 | 31 | 175 | 104 | 33 | 20 |
Figure S164. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 7e-05 (Fisher's exact test), Q value = 0.00045
Table S165. Gene #35: '19q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 19Q GAIN MUTATED | 8 | 7 | 7 | 24 | 9 |
| 19Q GAIN WILD-TYPE | 83 | 50 | 179 | 95 | 48 |
Figure S165. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S166. Gene #36: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 20P GAIN MUTATED | 16 | 27 | 41 | 3 | 19 | 6 |
| 20P GAIN WILD-TYPE | 45 | 53 | 115 | 79 | 61 | 63 |
Figure S166. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00051
Table S167. Gene #36: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 20P GAIN MUTATED | 10 | 16 | 33 | 6 |
| 20P GAIN WILD-TYPE | 57 | 54 | 63 | 75 |
Figure S167. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S168. Gene #36: '20p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 20P GAIN MUTATED | 19 | 5 | 45 | 11 | 19 | 2 |
| 20P GAIN WILD-TYPE | 69 | 81 | 45 | 71 | 73 | 31 |
Figure S168. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S169. Gene #36: '20p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 20P GAIN MUTATED | 18 | 35 | 34 | 14 |
| 20P GAIN WILD-TYPE | 117 | 77 | 51 | 125 |
Figure S169. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S170. Gene #36: '20p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 20P GAIN MUTATED | 18 | 9 | 20 | 60 | 5 |
| 20P GAIN WILD-TYPE | 63 | 161 | 61 | 93 | 35 |
Figure S170. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S171. Gene #36: '20p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 20P GAIN MUTATED | 20 | 4 | 13 | 66 | 3 | 6 |
| 20P GAIN WILD-TYPE | 97 | 29 | 170 | 66 | 32 | 19 |
Figure S171. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S172. Gene #36: '20p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 20P GAIN MUTATED | 18 | 13 | 16 | 48 | 16 |
| 20P GAIN WILD-TYPE | 73 | 44 | 170 | 71 | 41 |
Figure S172. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S173. Gene #36: '20p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 20P GAIN MUTATED | 55 | 23 | 33 |
| 20P GAIN WILD-TYPE | 118 | 186 | 95 |
Figure S173. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00028
Table S174. Gene #36: '20p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 20P GAIN MUTATED | 7 | 2 | 3 | 18 |
| 20P GAIN WILD-TYPE | 32 | 19 | 41 | 20 |
Figure S174. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0361 (Fisher's exact test), Q value = 0.083
Table S175. Gene #36: '20p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 40 | 52 | 28 | 22 |
| 20P GAIN MUTATED | 8 | 17 | 4 | 1 |
| 20P GAIN WILD-TYPE | 32 | 35 | 24 | 21 |
Figure S175. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S176. Gene #37: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 20Q GAIN MUTATED | 16 | 26 | 44 | 4 | 19 | 6 |
| 20Q GAIN WILD-TYPE | 45 | 54 | 112 | 78 | 61 | 63 |
Figure S176. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00039
Table S177. Gene #37: '20q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 20Q GAIN MUTATED | 10 | 16 | 33 | 6 |
| 20Q GAIN WILD-TYPE | 57 | 54 | 63 | 75 |
Figure S177. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S178. Gene #37: '20q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 20Q GAIN MUTATED | 19 | 5 | 47 | 12 | 19 | 2 |
| 20Q GAIN WILD-TYPE | 69 | 81 | 43 | 70 | 73 | 31 |
Figure S178. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S179. Gene #37: '20q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 20Q GAIN MUTATED | 18 | 38 | 34 | 14 |
| 20Q GAIN WILD-TYPE | 117 | 74 | 51 | 125 |
Figure S179. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S180. Gene #37: '20q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 20Q GAIN MUTATED | 18 | 9 | 19 | 64 | 5 |
| 20Q GAIN WILD-TYPE | 63 | 161 | 62 | 89 | 35 |
Figure S180. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S181. Gene #37: '20q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 20Q GAIN MUTATED | 20 | 4 | 13 | 69 | 3 | 6 |
| 20Q GAIN WILD-TYPE | 97 | 29 | 170 | 63 | 32 | 19 |
Figure S181. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S182. Gene #37: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 20Q GAIN MUTATED | 18 | 13 | 16 | 51 | 16 |
| 20Q GAIN WILD-TYPE | 73 | 44 | 170 | 68 | 41 |
Figure S182. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S183. Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 20Q GAIN MUTATED | 57 | 23 | 34 |
| 20Q GAIN WILD-TYPE | 116 | 186 | 94 |
Figure S183. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00022
Table S184. Gene #37: '20q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 20Q GAIN MUTATED | 7 | 2 | 3 | 19 |
| 20Q GAIN WILD-TYPE | 32 | 19 | 41 | 19 |
Figure S184. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0209 (Fisher's exact test), Q value = 0.056
Table S185. Gene #37: '20q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 40 | 52 | 28 | 22 |
| 20Q GAIN MUTATED | 8 | 18 | 4 | 1 |
| 20Q GAIN WILD-TYPE | 32 | 34 | 24 | 21 |
Figure S185. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00337 (Fisher's exact test), Q value = 0.013
Table S186. Gene #38: '21q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 21Q GAIN MUTATED | 3 | 6 | 18 | 3 |
| 21Q GAIN WILD-TYPE | 64 | 64 | 78 | 78 |
Figure S186. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00105 (Fisher's exact test), Q value = 0.0047
Table S187. Gene #38: '21q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 21Q GAIN MUTATED | 6 | 8 | 6 | 28 | 2 |
| 21Q GAIN WILD-TYPE | 75 | 162 | 75 | 125 | 38 |
Figure S187. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00314 (Fisher's exact test), Q value = 0.012
Table S188. Gene #38: '21q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 21Q GAIN MUTATED | 10 | 2 | 9 | 25 | 3 | 1 |
| 21Q GAIN WILD-TYPE | 107 | 31 | 174 | 107 | 32 | 24 |
Figure S188. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00802 (Fisher's exact test), Q value = 0.026
Table S189. Gene #38: '21q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 21Q GAIN MUTATED | 5 | 5 | 11 | 20 | 9 |
| 21Q GAIN WILD-TYPE | 86 | 52 | 175 | 99 | 48 |
Figure S189. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0159 (Fisher's exact test), Q value = 0.046
Table S190. Gene #39: '22q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 22Q GAIN MUTATED | 5 | 1 | 10 | 17 | 2 | 5 |
| 22Q GAIN WILD-TYPE | 112 | 32 | 173 | 115 | 33 | 20 |
Figure S190. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0196 (Fisher's exact test), Q value = 0.053
Table S191. Gene #39: '22q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 22Q GAIN MUTATED | 8 | 3 | 7 | 17 | 4 |
| 22Q GAIN WILD-TYPE | 83 | 54 | 179 | 102 | 53 |
Figure S191. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0421 (Fisher's exact test), Q value = 0.094
Table S192. Gene #40: 'xp gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| XP GAIN MUTATED | 9 | 5 | 10 | 1 | 3 | 4 |
| XP GAIN WILD-TYPE | 52 | 75 | 146 | 81 | 77 | 65 |
Figure S192. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00056
Table S193. Gene #40: 'xp gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| XP GAIN MUTATED | 12 | 0 | 10 | 2 | 3 | 0 |
| XP GAIN WILD-TYPE | 76 | 86 | 80 | 80 | 89 | 33 |
Figure S193. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00111 (Fisher's exact test), Q value = 0.0049
Table S194. Gene #40: 'xp gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| XP GAIN MUTATED | 5 | 6 | 13 | 3 |
| XP GAIN WILD-TYPE | 130 | 106 | 72 | 136 |
Figure S194. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0355 (Fisher's exact test), Q value = 0.082
Table S195. Gene #40: 'xp gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| XP GAIN MUTATED | 7 | 5 | 3 | 16 | 1 |
| XP GAIN WILD-TYPE | 74 | 165 | 78 | 137 | 39 |
Figure S195. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00077 (Fisher's exact test), Q value = 0.0036
Table S196. Gene #40: 'xp gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| XP GAIN MUTATED | 3 | 4 | 6 | 18 | 1 | 0 |
| XP GAIN WILD-TYPE | 114 | 29 | 177 | 114 | 34 | 25 |
Figure S196. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0472 (Fisher's exact test), Q value = 0.1
Table S197. Gene #40: 'xp gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| XP GAIN MUTATED | 6 | 4 | 6 | 14 | 2 |
| XP GAIN WILD-TYPE | 85 | 53 | 180 | 105 | 55 |
Figure S197. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0111 (Fisher's exact test), Q value = 0.033
Table S198. Gene #41: 'xq gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| XQ GAIN MUTATED | 9 | 4 | 6 | 1 | 4 | 7 |
| XQ GAIN WILD-TYPE | 52 | 76 | 150 | 81 | 76 | 62 |
Figure S198. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0225 (Fisher's exact test), Q value = 0.059
Table S199. Gene #41: 'xq gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| XQ GAIN MUTATED | 9 | 1 | 9 | 4 | 3 | 0 |
| XQ GAIN WILD-TYPE | 79 | 85 | 81 | 78 | 89 | 33 |
Figure S199. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00363 (Fisher's exact test), Q value = 0.014
Table S200. Gene #42: '1p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 1P LOSS MUTATED | 2 | 4 | 7 |
| 1P LOSS WILD-TYPE | 29 | 21 | 7 |
Figure S200. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00568 (Fisher's exact test), Q value = 0.019
Table S201. Gene #42: '1p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 1P LOSS MUTATED | 0 | 2 | 2 | 1 | 1 | 1 | 6 |
| 1P LOSS WILD-TYPE | 11 | 10 | 2 | 10 | 12 | 8 | 4 |
Figure S201. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00569 (Fisher's exact test), Q value = 0.019
Table S202. Gene #42: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 1P LOSS MUTATED | 2 | 7 | 21 | 4 | 11 | 15 |
| 1P LOSS WILD-TYPE | 59 | 73 | 135 | 78 | 69 | 54 |
Figure S202. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0135 (Fisher's exact test), Q value = 0.04
Table S203. Gene #42: '1p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 1P LOSS MUTATED | 19 | 7 | 9 | 9 | 4 | 4 |
| 1P LOSS WILD-TYPE | 69 | 79 | 81 | 73 | 88 | 29 |
Figure S203. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0108 (Fisher's exact test), Q value = 0.033
Table S204. Gene #42: '1p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 1P LOSS MUTATED | 6 | 14 | 15 | 17 |
| 1P LOSS WILD-TYPE | 129 | 98 | 70 | 122 |
Figure S204. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00022
Table S205. Gene #42: '1p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 1P LOSS MUTATED | 22 | 16 | 2 | 18 | 2 |
| 1P LOSS WILD-TYPE | 59 | 154 | 79 | 135 | 38 |
Figure S205. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00039
Table S206. Gene #42: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 1P LOSS MUTATED | 9 | 5 | 15 | 17 | 2 | 12 |
| 1P LOSS WILD-TYPE | 108 | 28 | 168 | 115 | 33 | 13 |
Figure S206. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00315 (Fisher's exact test), Q value = 0.012
Table S207. Gene #42: '1p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 1P LOSS MUTATED | 10 | 5 | 17 | 26 | 2 |
| 1P LOSS WILD-TYPE | 81 | 52 | 169 | 93 | 55 |
Figure S207. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0249 (Fisher's exact test), Q value = 0.063
Table S208. Gene #42: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 1P LOSS MUTATED | 16 | 20 | 24 |
| 1P LOSS WILD-TYPE | 157 | 189 | 104 |
Figure S208. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0381 (Fisher's exact test), Q value = 0.086
Table S209. Gene #43: '1q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 1Q LOSS MUTATED | 2 | 2 | 5 |
| 1Q LOSS WILD-TYPE | 29 | 23 | 9 |
Figure S209. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0115 (Fisher's exact test), Q value = 0.034
Table S210. Gene #43: '1q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 1Q LOSS MUTATED | 0 | 1 | 1 | 0 | 1 | 1 | 5 |
| 1Q LOSS WILD-TYPE | 11 | 11 | 3 | 11 | 12 | 8 | 5 |
Figure S210. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00011 (Fisher's exact test), Q value = 0.00066
Table S211. Gene #43: '1q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 1Q LOSS MUTATED | 1 | 6 | 4 | 3 | 11 | 12 |
| 1Q LOSS WILD-TYPE | 60 | 74 | 152 | 79 | 69 | 57 |
Figure S211. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0108 (Fisher's exact test), Q value = 0.033
Table S212. Gene #43: '1q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 1Q LOSS MUTATED | 9 | 1 | 8 | 2 |
| 1Q LOSS WILD-TYPE | 58 | 69 | 88 | 79 |
Figure S212. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0184 (Fisher's exact test), Q value = 0.051
Table S213. Gene #43: '1q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 1Q LOSS MUTATED | 13 | 4 | 8 | 3 | 2 | 2 |
| 1Q LOSS WILD-TYPE | 75 | 82 | 82 | 79 | 90 | 31 |
Figure S213. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00419 (Fisher's exact test), Q value = 0.015
Table S214. Gene #43: '1q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 1Q LOSS MUTATED | 3 | 10 | 12 | 7 |
| 1Q LOSS WILD-TYPE | 132 | 102 | 73 | 132 |
Figure S214. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S215. Gene #43: '1q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 1Q LOSS MUTATED | 17 | 8 | 0 | 11 | 1 |
| 1Q LOSS WILD-TYPE | 64 | 162 | 81 | 142 | 39 |
Figure S215. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S216. Gene #43: '1q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 1Q LOSS MUTATED | 5 | 2 | 7 | 10 | 2 | 11 |
| 1Q LOSS WILD-TYPE | 112 | 31 | 176 | 122 | 33 | 14 |
Figure S216. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0322 (Fisher's exact test), Q value = 0.077
Table S217. Gene #43: '1q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 1Q LOSS MUTATED | 6 | 3 | 8 | 17 | 3 |
| 1Q LOSS WILD-TYPE | 85 | 54 | 178 | 102 | 54 |
Figure S217. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0102 (Fisher's exact test), Q value = 0.032
Table S218. Gene #43: '1q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 1Q LOSS MUTATED | 11 | 9 | 17 |
| 1Q LOSS WILD-TYPE | 162 | 200 | 111 |
Figure S218. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 8e-05 (Fisher's exact test), Q value = 0.00051
Table S219. Gene #44: '2p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 2P LOSS MUTATED | 0 | 1 | 6 |
| 2P LOSS WILD-TYPE | 31 | 24 | 8 |
Figure S219. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00045 (Fisher's exact test), Q value = 0.0023
Table S220. Gene #44: '2p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 2P LOSS MUTATED | 0 | 1 | 1 | 0 | 0 | 0 | 5 |
| 2P LOSS WILD-TYPE | 11 | 11 | 3 | 11 | 13 | 9 | 5 |
Figure S220. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0336 (Fisher's exact test), Q value = 0.079
Table S221. Gene #44: '2p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 2P LOSS MUTATED | 0 | 3 | 2 | 1 | 2 | 6 |
| 2P LOSS WILD-TYPE | 61 | 77 | 154 | 81 | 78 | 63 |
Figure S221. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0221 (Fisher's exact test), Q value = 0.058
Table S222. Gene #44: '2p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 2P LOSS MUTATED | 4 | 0 | 2 | 0 |
| 2P LOSS WILD-TYPE | 63 | 70 | 94 | 81 |
Figure S222. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00062 (Fisher's exact test), Q value = 0.003
Table S223. Gene #44: '2p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 2P LOSS MUTATED | 7 | 0 | 2 | 0 | 0 | 0 |
| 2P LOSS WILD-TYPE | 81 | 86 | 88 | 82 | 92 | 33 |
Figure S223. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 2e-04 (Fisher's exact test), Q value = 0.0011
Table S224. Gene #44: '2p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 2P LOSS MUTATED | 0 | 1 | 7 | 1 |
| 2P LOSS WILD-TYPE | 135 | 111 | 78 | 138 |
Figure S224. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S225. Gene #44: '2p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 2P LOSS MUTATED | 12 | 0 | 0 | 2 | 0 |
| 2P LOSS WILD-TYPE | 69 | 170 | 81 | 151 | 40 |
Figure S225. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S226. Gene #44: '2p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 2P LOSS MUTATED | 0 | 2 | 1 | 2 | 0 | 9 |
| 2P LOSS WILD-TYPE | 117 | 31 | 182 | 130 | 35 | 16 |
Figure S226. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 7e-05 (Fisher's exact test), Q value = 0.00045
Table S227. Gene #44: '2p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 2P LOSS MUTATED | 2 | 1 | 0 | 11 | 0 |
| 2P LOSS WILD-TYPE | 89 | 56 | 186 | 108 | 57 |
Figure S227. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S228. Gene #44: '2p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 2P LOSS MUTATED | 1 | 1 | 12 |
| 2P LOSS WILD-TYPE | 172 | 208 | 116 |
Figure S228. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 4e-04 (Fisher's exact test), Q value = 0.002
Table S229. Gene #45: '2q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 2Q LOSS MUTATED | 0 | 1 | 5 |
| 2Q LOSS WILD-TYPE | 31 | 24 | 9 |
Figure S229. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00083 (Fisher's exact test), Q value = 0.0038
Table S230. Gene #45: '2q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 2Q LOSS MUTATED | 0 | 1 | 0 | 0 | 0 | 0 | 5 |
| 2Q LOSS WILD-TYPE | 11 | 11 | 4 | 11 | 13 | 9 | 5 |
Figure S230. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0102 (Fisher's exact test), Q value = 0.032
Table S231. Gene #45: '2q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 2Q LOSS MUTATED | 0 | 2 | 2 | 1 | 2 | 7 |
| 2Q LOSS WILD-TYPE | 61 | 78 | 154 | 81 | 78 | 62 |
Figure S231. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0294 (Fisher's exact test), Q value = 0.072
Table S232. Gene #45: '2q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 2Q LOSS MUTATED | 4 | 0 | 3 | 0 |
| 2Q LOSS WILD-TYPE | 63 | 70 | 93 | 81 |
Figure S232. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00344 (Fisher's exact test), Q value = 0.013
Table S233. Gene #45: '2q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 2Q LOSS MUTATED | 6 | 0 | 3 | 0 | 0 | 0 |
| 2Q LOSS WILD-TYPE | 82 | 86 | 87 | 82 | 92 | 33 |
Figure S233. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.00097
Table S234. Gene #45: '2q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 2Q LOSS MUTATED | 0 | 1 | 7 | 1 |
| 2Q LOSS WILD-TYPE | 135 | 111 | 78 | 138 |
Figure S234. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S235. Gene #45: '2q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 2Q LOSS MUTATED | 12 | 0 | 0 | 2 | 0 |
| 2Q LOSS WILD-TYPE | 69 | 170 | 81 | 151 | 40 |
Figure S235. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S236. Gene #45: '2q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 2Q LOSS MUTATED | 0 | 1 | 1 | 3 | 0 | 9 |
| 2Q LOSS WILD-TYPE | 117 | 32 | 182 | 129 | 35 | 16 |
Figure S236. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-04 (Fisher's exact test), Q value = 6e-04
Table S237. Gene #45: '2q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 2Q LOSS MUTATED | 1 | 1 | 0 | 11 | 1 |
| 2Q LOSS WILD-TYPE | 90 | 56 | 186 | 108 | 56 |
Figure S237. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S238. Gene #45: '2q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 2Q LOSS MUTATED | 1 | 0 | 13 |
| 2Q LOSS WILD-TYPE | 172 | 209 | 115 |
Figure S238. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00612 (Fisher's exact test), Q value = 0.02
Table S239. Gene #46: '3p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 3P LOSS MUTATED | 20 | 20 | 4 |
| 3P LOSS WILD-TYPE | 11 | 5 | 10 |
Figure S239. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0103 (Fisher's exact test), Q value = 0.032
Table S240. Gene #46: '3p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 3P LOSS MUTATED | 8 | 9 | 1 | 10 | 7 | 7 | 2 |
| 3P LOSS WILD-TYPE | 3 | 3 | 3 | 1 | 6 | 2 | 8 |
Figure S240. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S241. Gene #46: '3p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 3P LOSS MUTATED | 50 | 33 | 137 | 69 | 38 | 52 |
| 3P LOSS WILD-TYPE | 11 | 47 | 19 | 13 | 42 | 17 |
Figure S241. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00942 (Fisher's exact test), Q value = 0.03
Table S242. Gene #46: '3p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 3P LOSS MUTATED | 41 | 50 | 72 | 69 |
| 3P LOSS WILD-TYPE | 26 | 20 | 24 | 12 |
Figure S242. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0113 (Fisher's exact test), Q value = 0.034
Table S243. Gene #46: '3p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 3P LOSS MUTATED | 52 | 70 | 63 | 65 | 62 | 26 |
| 3P LOSS WILD-TYPE | 36 | 16 | 27 | 17 | 30 | 7 |
Figure S243. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.00092
Table S244. Gene #46: '3p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 3P LOSS MUTATED | 95 | 90 | 45 | 108 |
| 3P LOSS WILD-TYPE | 40 | 22 | 40 | 31 |
Figure S244. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S245. Gene #46: '3p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 3P LOSS MUTATED | 31 | 141 | 61 | 115 | 29 |
| 3P LOSS WILD-TYPE | 50 | 29 | 20 | 38 | 11 |
Figure S245. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S246. Gene #46: '3p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 3P LOSS MUTATED | 92 | 14 | 148 | 96 | 25 | 2 |
| 3P LOSS WILD-TYPE | 25 | 19 | 35 | 36 | 10 | 23 |
Figure S246. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0149 (Fisher's exact test), Q value = 0.043
Table S247. Gene #46: '3p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 3P LOSS MUTATED | 58 | 42 | 146 | 75 | 44 |
| 3P LOSS WILD-TYPE | 33 | 15 | 40 | 44 | 13 |
Figure S247. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00419 (Fisher's exact test), Q value = 0.015
Table S248. Gene #46: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 3P LOSS MUTATED | 114 | 166 | 85 |
| 3P LOSS WILD-TYPE | 59 | 43 | 43 |
Figure S248. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0236 (Fisher's exact test), Q value = 0.061
Table S249. Gene #46: '3p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 3P LOSS MUTATED | 26 | 10 | 36 | 22 |
| 3P LOSS WILD-TYPE | 13 | 11 | 8 | 16 |
Figure S249. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00021 (Fisher's exact test), Q value = 0.0011
Table S250. Gene #47: '3q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 3Q LOSS MUTATED | 16 | 14 | 34 | 24 | 3 | 11 |
| 3Q LOSS WILD-TYPE | 45 | 66 | 122 | 58 | 77 | 58 |
Figure S250. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00658 (Fisher's exact test), Q value = 0.022
Table S251. Gene #47: '3q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 3Q LOSS MUTATED | 35 | 5 | 28 | 29 | 4 | 1 |
| 3Q LOSS WILD-TYPE | 82 | 28 | 155 | 103 | 31 | 24 |
Figure S251. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0138 (Fisher's exact test), Q value = 0.04
Table S252. Gene #47: '3q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 3Q LOSS MUTATED | 14 | 9 | 30 | 25 | 21 |
| 3Q LOSS WILD-TYPE | 77 | 48 | 156 | 94 | 36 |
Figure S252. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00457 (Fisher's exact test), Q value = 0.016
Table S253. Gene #48: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 4P LOSS MUTATED | 4 | 11 | 25 | 10 |
| 4P LOSS WILD-TYPE | 63 | 59 | 71 | 71 |
Figure S253. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 4e-04 (Fisher's exact test), Q value = 0.002
Table S254. Gene #48: '4p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 4P LOSS MUTATED | 6 | 11 | 26 | 10 | 15 | 1 |
| 4P LOSS WILD-TYPE | 82 | 75 | 64 | 72 | 77 | 32 |
Figure S254. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00146 (Fisher's exact test), Q value = 0.0062
Table S255. Gene #48: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 4P LOSS MUTATED | 16 | 1 | 19 | 31 | 4 | 0 |
| 4P LOSS WILD-TYPE | 101 | 32 | 164 | 101 | 31 | 25 |
Figure S255. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.044 (Fisher's exact test), Q value = 0.098
Table S256. Gene #48: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 40 | 52 | 28 | 22 |
| 4P LOSS MUTATED | 2 | 12 | 3 | 1 |
| 4P LOSS WILD-TYPE | 38 | 40 | 25 | 21 |
Figure S256. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00387 (Fisher's exact test), Q value = 0.014
Table S257. Gene #49: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 4Q LOSS MUTATED | 4 | 9 | 24 | 8 |
| 4Q LOSS WILD-TYPE | 63 | 61 | 72 | 73 |
Figure S257. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00033 (Fisher's exact test), Q value = 0.0017
Table S258. Gene #49: '4q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 4Q LOSS MUTATED | 7 | 8 | 26 | 9 | 12 | 1 |
| 4Q LOSS WILD-TYPE | 81 | 78 | 64 | 73 | 80 | 32 |
Figure S258. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0162 (Fisher's exact test), Q value = 0.046
Table S259. Gene #49: '4q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 4Q LOSS MUTATED | 12 | 21 | 17 | 13 |
| 4Q LOSS WILD-TYPE | 123 | 91 | 68 | 126 |
Figure S259. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00377 (Fisher's exact test), Q value = 0.014
Table S260. Gene #49: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 4Q LOSS MUTATED | 4 | 13 | 13 | 28 | 7 |
| 4Q LOSS WILD-TYPE | 77 | 157 | 68 | 125 | 33 |
Figure S260. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00034
Table S261. Gene #49: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 4Q LOSS MUTATED | 15 | 0 | 14 | 32 | 4 | 0 |
| 4Q LOSS WILD-TYPE | 102 | 33 | 169 | 100 | 31 | 25 |
Figure S261. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0262 (Fisher's exact test), Q value = 0.066
Table S262. Gene #49: '4q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 40 | 52 | 28 | 22 |
| 4Q LOSS MUTATED | 2 | 11 | 3 | 0 |
| 4Q LOSS WILD-TYPE | 38 | 41 | 25 | 22 |
Figure S262. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00223 (Fisher's exact test), Q value = 0.0088
Table S263. Gene #50: '5p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 5P LOSS MUTATED | 0 | 0 | 6 | 0 | 1 | 0 |
| 5P LOSS WILD-TYPE | 88 | 86 | 84 | 82 | 91 | 33 |
Figure S263. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.026 (Fisher's exact test), Q value = 0.066
Table S264. Gene #50: '5p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 5P LOSS MUTATED | 1 | 2 | 4 | 0 |
| 5P LOSS WILD-TYPE | 134 | 110 | 81 | 139 |
Figure S264. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0052 (Fisher's exact test), Q value = 0.018
Table S265. Gene #50: '5p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 5P LOSS MUTATED | 0 | 0 | 0 | 6 | 1 | 1 |
| 5P LOSS WILD-TYPE | 117 | 33 | 183 | 126 | 34 | 24 |
Figure S265. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0236 (Fisher's exact test), Q value = 0.061
Table S266. Gene #50: '5p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 5P LOSS MUTATED | 2 | 1 | 0 | 5 | 0 |
| 5P LOSS WILD-TYPE | 89 | 56 | 186 | 114 | 57 |
Figure S266. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0274 (Fisher's exact test), Q value = 0.068
Table S267. Gene #50: '5p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 5P LOSS MUTATED | 5 | 0 | 3 |
| 5P LOSS WILD-TYPE | 168 | 209 | 125 |
Figure S267. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0103 (Fisher's exact test), Q value = 0.032
Table S268. Gene #51: '5q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 5Q LOSS MUTATED | 0 | 0 | 5 | 0 | 1 | 0 |
| 5Q LOSS WILD-TYPE | 88 | 86 | 85 | 82 | 91 | 33 |
Figure S268. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00632 (Fisher's exact test), Q value = 0.021
Table S269. Gene #51: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 5Q LOSS MUTATED | 0 | 0 | 0 | 6 | 0 | 1 |
| 5Q LOSS WILD-TYPE | 117 | 33 | 183 | 126 | 35 | 24 |
Figure S269. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.049 (Fisher's exact test), Q value = 0.11
Table S270. Gene #51: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 5Q LOSS MUTATED | 2 | 1 | 0 | 4 | 0 |
| 5Q LOSS WILD-TYPE | 89 | 56 | 186 | 115 | 57 |
Figure S270. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0317 (Fisher's exact test), Q value = 0.076
Table S271. Gene #51: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 5Q LOSS MUTATED | 5 | 0 | 2 |
| 5Q LOSS WILD-TYPE | 168 | 209 | 126 |
Figure S271. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0313 (Fisher's exact test), Q value = 0.076
Table S272. Gene #52: '6p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 6P LOSS MUTATED | 4 | 10 | 6 |
| 6P LOSS WILD-TYPE | 27 | 15 | 8 |
Figure S272. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0142 (Fisher's exact test), Q value = 0.041
Table S273. Gene #52: '6p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 6P LOSS MUTATED | 2 | 7 | 0 | 3 | 1 | 1 | 6 |
| 6P LOSS WILD-TYPE | 9 | 5 | 4 | 8 | 12 | 8 | 4 |
Figure S273. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S274. Gene #52: '6p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 6P LOSS MUTATED | 7 | 10 | 61 | 0 | 14 | 8 |
| 6P LOSS WILD-TYPE | 54 | 70 | 95 | 82 | 66 | 61 |
Figure S274. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00315 (Fisher's exact test), Q value = 0.012
Table S275. Gene #52: '6p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 6P LOSS MUTATED | 9 | 13 | 25 | 5 |
| 6P LOSS WILD-TYPE | 58 | 57 | 71 | 76 |
Figure S275. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S276. Gene #52: '6p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 6P LOSS MUTATED | 16 | 9 | 37 | 17 | 7 | 4 |
| 6P LOSS WILD-TYPE | 72 | 77 | 53 | 65 | 85 | 29 |
Figure S276. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S277. Gene #52: '6p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 6P LOSS MUTATED | 10 | 40 | 27 | 13 |
| 6P LOSS WILD-TYPE | 125 | 72 | 58 | 126 |
Figure S277. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S278. Gene #52: '6p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 6P LOSS MUTATED | 16 | 15 | 9 | 53 | 5 |
| 6P LOSS WILD-TYPE | 65 | 155 | 72 | 100 | 35 |
Figure S278. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S279. Gene #52: '6p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 6P LOSS MUTATED | 19 | 1 | 12 | 51 | 6 | 9 |
| 6P LOSS WILD-TYPE | 98 | 32 | 171 | 81 | 29 | 16 |
Figure S279. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S280. Gene #52: '6p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 6P LOSS MUTATED | 15 | 15 | 15 | 40 | 11 |
| 6P LOSS WILD-TYPE | 76 | 42 | 171 | 79 | 46 |
Figure S280. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S281. Gene #52: '6p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 6P LOSS MUTATED | 44 | 14 | 38 |
| 6P LOSS WILD-TYPE | 129 | 195 | 90 |
Figure S281. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0304 (Fisher's exact test), Q value = 0.074
Table S282. Gene #52: '6p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 40 | 52 | 28 | 22 |
| 6P LOSS MUTATED | 5 | 13 | 3 | 0 |
| 6P LOSS WILD-TYPE | 35 | 39 | 25 | 22 |
Figure S282. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S283. Gene #53: '6q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 6Q LOSS MUTATED | 7 | 10 | 85 | 0 | 16 | 10 |
| 6Q LOSS WILD-TYPE | 54 | 70 | 71 | 82 | 64 | 59 |
Figure S283. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S284. Gene #53: '6q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 6Q LOSS MUTATED | 18 | 21 | 39 | 25 | 7 | 5 |
| 6Q LOSS WILD-TYPE | 70 | 65 | 51 | 57 | 85 | 28 |
Figure S284. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S285. Gene #53: '6q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 6Q LOSS MUTATED | 13 | 45 | 29 | 28 |
| 6Q LOSS WILD-TYPE | 122 | 67 | 56 | 111 |
Figure S285. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00039
Table S286. Gene #53: '6q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 6Q LOSS MUTATED | 19 | 33 | 11 | 58 | 5 |
| 6Q LOSS WILD-TYPE | 62 | 137 | 70 | 95 | 35 |
Figure S286. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S287. Gene #53: '6q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 6Q LOSS MUTATED | 22 | 5 | 29 | 53 | 8 | 9 |
| 6Q LOSS WILD-TYPE | 95 | 28 | 154 | 79 | 27 | 16 |
Figure S287. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00172 (Fisher's exact test), Q value = 0.0071
Table S288. Gene #53: '6q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 6Q LOSS MUTATED | 20 | 17 | 31 | 44 | 12 |
| 6Q LOSS WILD-TYPE | 71 | 40 | 155 | 75 | 45 |
Figure S288. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 6e-04
Table S289. Gene #53: '6q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 6Q LOSS MUTATED | 50 | 31 | 43 |
| 6Q LOSS WILD-TYPE | 123 | 178 | 85 |
Figure S289. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.031 (Fisher's exact test), Q value = 0.075
Table S290. Gene #53: '6q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 40 | 52 | 28 | 22 |
| 6Q LOSS MUTATED | 6 | 17 | 5 | 1 |
| 6Q LOSS WILD-TYPE | 34 | 35 | 23 | 21 |
Figure S290. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0491 (Fisher's exact test), Q value = 0.11
Table S291. Gene #54: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 8P LOSS MUTATED | 14 | 22 | 53 | 14 | 15 | 19 |
| 8P LOSS WILD-TYPE | 47 | 58 | 103 | 68 | 65 | 50 |
Figure S291. Get High-res Image Gene #54: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.032 (Fisher's exact test), Q value = 0.077
Table S292. Gene #54: '8p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 8P LOSS MUTATED | 15 | 40 | 16 | 53 | 12 |
| 8P LOSS WILD-TYPE | 66 | 130 | 65 | 100 | 28 |
Figure S292. Get High-res Image Gene #54: '8p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00125 (Fisher's exact test), Q value = 0.0054
Table S293. Gene #54: '8p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 8P LOSS MUTATED | 28 | 3 | 47 | 50 | 4 | 4 |
| 8P LOSS WILD-TYPE | 89 | 30 | 136 | 82 | 31 | 21 |
Figure S293. Get High-res Image Gene #54: '8p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0179 (Fisher's exact test), Q value = 0.05
Table S294. Gene #54: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 8P LOSS MUTATED | 59 | 46 | 29 |
| 8P LOSS WILD-TYPE | 114 | 163 | 99 |
Figure S294. Get High-res Image Gene #54: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00723 (Fisher's exact test), Q value = 0.023
Table S295. Gene #55: '8q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 8Q LOSS MUTATED | 11 | 1 | 14 | 10 |
| 8Q LOSS WILD-TYPE | 56 | 69 | 82 | 71 |
Figure S295. Get High-res Image Gene #55: '8q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0214 (Fisher's exact test), Q value = 0.056
Table S296. Gene #55: '8q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 8Q LOSS MUTATED | 13 | 3 | 13 | 16 | 9 | 5 |
| 8Q LOSS WILD-TYPE | 75 | 83 | 77 | 66 | 83 | 28 |
Figure S296. Get High-res Image Gene #55: '8q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00706 (Fisher's exact test), Q value = 0.023
Table S297. Gene #56: '9p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 9P LOSS MUTATED | 5 | 12 | 1 |
| 9P LOSS WILD-TYPE | 26 | 13 | 13 |
Figure S297. Get High-res Image Gene #56: '9p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0362 (Fisher's exact test), Q value = 0.083
Table S298. Gene #56: '9p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 9P LOSS MUTATED | 2 | 7 | 0 | 5 | 1 | 2 | 1 |
| 9P LOSS WILD-TYPE | 9 | 5 | 4 | 6 | 12 | 7 | 9 |
Figure S298. Get High-res Image Gene #56: '9p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S299. Gene #56: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 9P LOSS MUTATED | 6 | 21 | 85 | 17 | 20 | 0 |
| 9P LOSS WILD-TYPE | 55 | 59 | 71 | 65 | 60 | 69 |
Figure S299. Get High-res Image Gene #56: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S300. Gene #56: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 9P LOSS MUTATED | 9 | 24 | 56 | 4 |
| 9P LOSS WILD-TYPE | 58 | 46 | 40 | 77 |
Figure S300. Get High-res Image Gene #56: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S301. Gene #56: '9p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 9P LOSS MUTATED | 16 | 15 | 54 | 22 | 25 | 6 |
| 9P LOSS WILD-TYPE | 72 | 71 | 36 | 60 | 67 | 27 |
Figure S301. Get High-res Image Gene #56: '9p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S302. Gene #56: '9p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 9P LOSS MUTATED | 25 | 52 | 36 | 25 |
| 9P LOSS WILD-TYPE | 110 | 60 | 49 | 114 |
Figure S302. Get High-res Image Gene #56: '9p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S303. Gene #56: '9p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 9P LOSS MUTATED | 14 | 16 | 23 | 88 | 7 |
| 9P LOSS WILD-TYPE | 67 | 154 | 58 | 65 | 33 |
Figure S303. Get High-res Image Gene #56: '9p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S304. Gene #56: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 9P LOSS MUTATED | 31 | 2 | 16 | 82 | 13 | 4 |
| 9P LOSS WILD-TYPE | 86 | 31 | 167 | 50 | 22 | 21 |
Figure S304. Get High-res Image Gene #56: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S305. Gene #56: '9p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 9P LOSS MUTATED | 21 | 23 | 27 | 60 | 13 |
| 9P LOSS WILD-TYPE | 70 | 34 | 159 | 59 | 44 |
Figure S305. Get High-res Image Gene #56: '9p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S306. Gene #56: '9p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 9P LOSS MUTATED | 70 | 25 | 49 |
| 9P LOSS WILD-TYPE | 103 | 184 | 79 |
Figure S306. Get High-res Image Gene #56: '9p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0109 (Fisher's exact test), Q value = 0.033
Table S307. Gene #56: '9p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 9P LOSS MUTATED | 8 | 4 | 4 | 15 |
| 9P LOSS WILD-TYPE | 31 | 17 | 40 | 23 |
Figure S307. Get High-res Image Gene #56: '9p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0191 (Fisher's exact test), Q value = 0.052
Table S308. Gene #57: '9q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 9Q LOSS MUTATED | 5 | 12 | 2 |
| 9Q LOSS WILD-TYPE | 26 | 13 | 12 |
Figure S308. Get High-res Image Gene #57: '9q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S309. Gene #57: '9q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 9Q LOSS MUTATED | 6 | 20 | 86 | 18 | 21 | 0 |
| 9Q LOSS WILD-TYPE | 55 | 60 | 70 | 64 | 59 | 69 |
Figure S309. Get High-res Image Gene #57: '9q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S310. Gene #57: '9q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 9Q LOSS MUTATED | 9 | 25 | 54 | 3 |
| 9Q LOSS WILD-TYPE | 58 | 45 | 42 | 78 |
Figure S310. Get High-res Image Gene #57: '9q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S311. Gene #57: '9q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 9Q LOSS MUTATED | 18 | 14 | 52 | 24 | 26 | 6 |
| 9Q LOSS WILD-TYPE | 70 | 72 | 38 | 58 | 66 | 27 |
Figure S311. Get High-res Image Gene #57: '9q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S312. Gene #57: '9q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 9Q LOSS MUTATED | 26 | 52 | 36 | 26 |
| 9Q LOSS WILD-TYPE | 109 | 60 | 49 | 113 |
Figure S312. Get High-res Image Gene #57: '9q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S313. Gene #57: '9q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 9Q LOSS MUTATED | 15 | 17 | 23 | 88 | 7 |
| 9Q LOSS WILD-TYPE | 66 | 153 | 58 | 65 | 33 |
Figure S313. Get High-res Image Gene #57: '9q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S314. Gene #57: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 9Q LOSS MUTATED | 32 | 3 | 16 | 82 | 13 | 4 |
| 9Q LOSS WILD-TYPE | 85 | 30 | 167 | 50 | 22 | 21 |
Figure S314. Get High-res Image Gene #57: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S315. Gene #57: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 9Q LOSS MUTATED | 20 | 23 | 26 | 62 | 14 |
| 9Q LOSS WILD-TYPE | 71 | 34 | 160 | 57 | 43 |
Figure S315. Get High-res Image Gene #57: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S316. Gene #57: '9q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 9Q LOSS MUTATED | 69 | 25 | 51 |
| 9Q LOSS WILD-TYPE | 104 | 184 | 77 |
Figure S316. Get High-res Image Gene #57: '9q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00256 (Fisher's exact test), Q value = 0.01
Table S317. Gene #57: '9q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 9Q LOSS MUTATED | 6 | 4 | 5 | 17 |
| 9Q LOSS WILD-TYPE | 33 | 17 | 39 | 21 |
Figure S317. Get High-res Image Gene #57: '9q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0177 (Fisher's exact test), Q value = 0.049
Table S318. Gene #58: '10p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 10P LOSS MUTATED | 9 | 18 | 17 | 16 |
| 10P LOSS WILD-TYPE | 126 | 94 | 68 | 123 |
Figure S318. Get High-res Image Gene #58: '10p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00055 (Fisher's exact test), Q value = 0.0027
Table S319. Gene #58: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 10P LOSS MUTATED | 16 | 3 | 13 | 25 | 2 | 9 |
| 10P LOSS WILD-TYPE | 101 | 30 | 170 | 107 | 33 | 16 |
Figure S319. Get High-res Image Gene #58: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00739 (Fisher's exact test), Q value = 0.024
Table S320. Gene #58: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 10P LOSS MUTATED | 11 | 4 | 16 | 27 | 8 |
| 10P LOSS WILD-TYPE | 80 | 53 | 170 | 92 | 49 |
Figure S320. Get High-res Image Gene #58: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0309 (Fisher's exact test), Q value = 0.075
Table S321. Gene #58: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 10P LOSS MUTATED | 25 | 18 | 23 |
| 10P LOSS WILD-TYPE | 148 | 191 | 105 |
Figure S321. Get High-res Image Gene #58: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0293 (Fisher's exact test), Q value = 0.072
Table S322. Gene #59: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 10Q LOSS MUTATED | 6 | 11 | 35 | 7 | 14 | 16 |
| 10Q LOSS WILD-TYPE | 55 | 69 | 121 | 75 | 66 | 53 |
Figure S322. Get High-res Image Gene #59: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0213 (Fisher's exact test), Q value = 0.056
Table S323. Gene #59: '10q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 10Q LOSS MUTATED | 14 | 24 | 21 | 22 |
| 10Q LOSS WILD-TYPE | 121 | 88 | 64 | 117 |
Figure S323. Get High-res Image Gene #59: '10q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00193 (Fisher's exact test), Q value = 0.0077
Table S324. Gene #59: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 10Q LOSS MUTATED | 22 | 3 | 20 | 32 | 3 | 9 |
| 10Q LOSS WILD-TYPE | 95 | 30 | 163 | 100 | 32 | 16 |
Figure S324. Get High-res Image Gene #59: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00261 (Fisher's exact test), Q value = 0.01
Table S325. Gene #59: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 10Q LOSS MUTATED | 14 | 4 | 24 | 33 | 12 |
| 10Q LOSS WILD-TYPE | 77 | 53 | 162 | 86 | 45 |
Figure S325. Get High-res Image Gene #59: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00572 (Fisher's exact test), Q value = 0.019
Table S326. Gene #59: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 10Q LOSS MUTATED | 34 | 23 | 30 |
| 10Q LOSS WILD-TYPE | 139 | 186 | 98 |
Figure S326. Get High-res Image Gene #59: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0276 (Fisher's exact test), Q value = 0.068
Table S327. Gene #60: '11p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 11P LOSS MUTATED | 3 | 1 | 2 | 11 | 1 | 0 |
| 11P LOSS WILD-TYPE | 114 | 32 | 181 | 121 | 34 | 25 |
Figure S327. Get High-res Image Gene #60: '11p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0344 (Fisher's exact test), Q value = 0.08
Table S328. Gene #60: '11p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 11P LOSS MUTATED | 11 | 3 | 4 |
| 11P LOSS WILD-TYPE | 162 | 206 | 124 |
Figure S328. Get High-res Image Gene #60: '11p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0102 (Fisher's exact test), Q value = 0.032
Table S329. Gene #61: '11q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 11Q LOSS MUTATED | 2 | 10 | 6 | 3 |
| 11Q LOSS WILD-TYPE | 133 | 102 | 79 | 136 |
Figure S329. Get High-res Image Gene #61: '11q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00624 (Fisher's exact test), Q value = 0.021
Table S330. Gene #61: '11q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 11Q LOSS MUTATED | 6 | 3 | 1 | 13 | 0 |
| 11Q LOSS WILD-TYPE | 75 | 167 | 80 | 140 | 40 |
Figure S330. Get High-res Image Gene #61: '11q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00037 (Fisher's exact test), Q value = 0.0019
Table S331. Gene #61: '11q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 11Q LOSS MUTATED | 3 | 1 | 2 | 16 | 1 | 0 |
| 11Q LOSS WILD-TYPE | 114 | 32 | 181 | 116 | 34 | 25 |
Figure S331. Get High-res Image Gene #61: '11q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0164 (Fisher's exact test), Q value = 0.046
Table S332. Gene #61: '11q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 11Q LOSS MUTATED | 7 | 0 | 4 | 10 | 2 |
| 11Q LOSS WILD-TYPE | 84 | 57 | 182 | 109 | 55 |
Figure S332. Get High-res Image Gene #61: '11q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00976 (Fisher's exact test), Q value = 0.031
Table S333. Gene #61: '11q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 11Q LOSS MUTATED | 13 | 3 | 7 |
| 11Q LOSS WILD-TYPE | 160 | 206 | 121 |
Figure S333. Get High-res Image Gene #61: '11q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00899 (Fisher's exact test), Q value = 0.029
Table S334. Gene #62: '12p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 12P LOSS MUTATED | 0 | 0 | 0 | 0 | 1 | 3 |
| 12P LOSS WILD-TYPE | 61 | 80 | 156 | 82 | 79 | 66 |
Figure S334. Get High-res Image Gene #62: '12p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00662 (Fisher's exact test), Q value = 0.022
Table S335. Gene #64: '13q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 13Q LOSS MUTATED | 0 | 6 | 3 |
| 13Q LOSS WILD-TYPE | 31 | 19 | 11 |
Figure S335. Get High-res Image Gene #64: '13q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0462 (Fisher's exact test), Q value = 0.1
Table S336. Gene #64: '13q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 13Q LOSS MUTATED | 0 | 3 | 0 | 3 | 0 | 0 | 3 |
| 13Q LOSS WILD-TYPE | 11 | 9 | 4 | 8 | 13 | 9 | 7 |
Figure S336. Get High-res Image Gene #64: '13q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.024 (Fisher's exact test), Q value = 0.061
Table S337. Gene #64: '13q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 13Q LOSS MUTATED | 3 | 10 | 29 | 6 | 15 | 7 |
| 13Q LOSS WILD-TYPE | 58 | 70 | 127 | 76 | 65 | 62 |
Figure S337. Get High-res Image Gene #64: '13q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00094 (Fisher's exact test), Q value = 0.0042
Table S338. Gene #64: '13q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 13Q LOSS MUTATED | 7 | 16 | 19 | 3 |
| 13Q LOSS WILD-TYPE | 60 | 54 | 77 | 78 |
Figure S338. Get High-res Image Gene #64: '13q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S339. Gene #64: '13q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 13Q LOSS MUTATED | 11 | 2 | 30 | 9 | 9 | 1 |
| 13Q LOSS WILD-TYPE | 77 | 84 | 60 | 73 | 83 | 32 |
Figure S339. Get High-res Image Gene #64: '13q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00015
Table S340. Gene #64: '13q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 13Q LOSS MUTATED | 8 | 22 | 22 | 10 |
| 13Q LOSS WILD-TYPE | 127 | 90 | 63 | 129 |
Figure S340. Get High-res Image Gene #64: '13q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S341. Gene #64: '13q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 13Q LOSS MUTATED | 13 | 11 | 6 | 40 | 0 |
| 13Q LOSS WILD-TYPE | 68 | 159 | 75 | 113 | 40 |
Figure S341. Get High-res Image Gene #64: '13q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S342. Gene #64: '13q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 13Q LOSS MUTATED | 6 | 2 | 9 | 40 | 6 | 7 |
| 13Q LOSS WILD-TYPE | 111 | 31 | 174 | 92 | 29 | 18 |
Figure S342. Get High-res Image Gene #64: '13q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S343. Gene #64: '13q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 13Q LOSS MUTATED | 9 | 9 | 10 | 35 | 5 |
| 13Q LOSS WILD-TYPE | 82 | 48 | 176 | 84 | 52 |
Figure S343. Get High-res Image Gene #64: '13q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S344. Gene #64: '13q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 13Q LOSS MUTATED | 30 | 9 | 29 |
| 13Q LOSS WILD-TYPE | 143 | 200 | 99 |
Figure S344. Get High-res Image Gene #64: '13q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S345. Gene #65: '14q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 14Q LOSS MUTATED | 8 | 20 | 2 |
| 14Q LOSS WILD-TYPE | 23 | 5 | 12 |
Figure S345. Get High-res Image Gene #65: '14q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00039
Table S346. Gene #65: '14q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 14Q LOSS MUTATED | 4 | 7 | 1 | 11 | 5 | 0 | 2 |
| 14Q LOSS WILD-TYPE | 7 | 5 | 3 | 0 | 8 | 9 | 8 |
Figure S346. Get High-res Image Gene #65: '14q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S347. Gene #65: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 14Q LOSS MUTATED | 22 | 32 | 98 | 25 | 34 | 5 |
| 14Q LOSS WILD-TYPE | 39 | 48 | 58 | 57 | 46 | 64 |
Figure S347. Get High-res Image Gene #65: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S348. Gene #65: '14q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 14Q LOSS MUTATED | 16 | 34 | 59 | 14 |
| 14Q LOSS WILD-TYPE | 51 | 36 | 37 | 67 |
Figure S348. Get High-res Image Gene #65: '14q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S349. Gene #65: '14q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 14Q LOSS MUTATED | 29 | 22 | 57 | 53 | 31 | 6 |
| 14Q LOSS WILD-TYPE | 59 | 64 | 33 | 29 | 61 | 27 |
Figure S349. Get High-res Image Gene #65: '14q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0131 (Fisher's exact test), Q value = 0.039
Table S350. Gene #65: '14q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 14Q LOSS MUTATED | 45 | 54 | 45 | 54 |
| 14Q LOSS WILD-TYPE | 90 | 58 | 40 | 85 |
Figure S350. Get High-res Image Gene #65: '14q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S351. Gene #65: '14q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 14Q LOSS MUTATED | 19 | 54 | 22 | 109 | 9 |
| 14Q LOSS WILD-TYPE | 62 | 116 | 59 | 44 | 31 |
Figure S351. Get High-res Image Gene #65: '14q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S352. Gene #65: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 14Q LOSS MUTATED | 41 | 7 | 52 | 79 | 32 | 2 |
| 14Q LOSS WILD-TYPE | 76 | 26 | 131 | 53 | 3 | 23 |
Figure S352. Get High-res Image Gene #65: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S353. Gene #65: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 14Q LOSS MUTATED | 27 | 34 | 61 | 76 | 12 |
| 14Q LOSS WILD-TYPE | 64 | 23 | 125 | 43 | 45 |
Figure S353. Get High-res Image Gene #65: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S354. Gene #65: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 14Q LOSS MUTATED | 72 | 64 | 74 |
| 14Q LOSS WILD-TYPE | 101 | 145 | 54 |
Figure S354. Get High-res Image Gene #65: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0441 (Fisher's exact test), Q value = 0.098
Table S355. Gene #65: '14q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 40 | 52 | 28 | 22 |
| 14Q LOSS MUTATED | 12 | 20 | 14 | 3 |
| 14Q LOSS WILD-TYPE | 28 | 32 | 14 | 19 |
Figure S355. Get High-res Image Gene #65: '14q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.005 (Fisher's exact test), Q value = 0.018
Table S356. Gene #66: '15q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 15Q LOSS MUTATED | 2 | 2 | 21 | 4 | 5 | 1 |
| 15Q LOSS WILD-TYPE | 59 | 78 | 135 | 78 | 75 | 68 |
Figure S356. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0292 (Fisher's exact test), Q value = 0.072
Table S357. Gene #66: '15q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 15Q LOSS MUTATED | 7 | 2 | 14 | 4 | 5 | 2 |
| 15Q LOSS WILD-TYPE | 81 | 84 | 76 | 78 | 87 | 31 |
Figure S357. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.016 (Fisher's exact test), Q value = 0.046
Table S358. Gene #66: '15q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 15Q LOSS MUTATED | 5 | 14 | 9 | 6 |
| 15Q LOSS WILD-TYPE | 130 | 98 | 76 | 133 |
Figure S358. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 7e-05 (Fisher's exact test), Q value = 0.00045
Table S359. Gene #66: '15q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 15Q LOSS MUTATED | 2 | 4 | 6 | 23 | 0 |
| 15Q LOSS WILD-TYPE | 79 | 166 | 75 | 130 | 40 |
Figure S359. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S360. Gene #66: '15q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 15Q LOSS MUTATED | 5 | 0 | 4 | 24 | 2 | 0 |
| 15Q LOSS WILD-TYPE | 112 | 33 | 179 | 108 | 33 | 25 |
Figure S360. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00701 (Fisher's exact test), Q value = 0.023
Table S361. Gene #66: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 15Q LOSS MUTATED | 5 | 6 | 6 | 16 | 2 |
| 15Q LOSS WILD-TYPE | 86 | 51 | 180 | 103 | 55 |
Figure S361. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00654 (Fisher's exact test), Q value = 0.022
Table S362. Gene #66: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 15Q LOSS MUTATED | 18 | 6 | 11 |
| 15Q LOSS WILD-TYPE | 155 | 203 | 117 |
Figure S362. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0493 (Fisher's exact test), Q value = 0.11
Table S363. Gene #67: '16p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 16P LOSS MUTATED | 0 | 3 | 4 | 2 |
| 16P LOSS WILD-TYPE | 135 | 109 | 81 | 137 |
Figure S363. Get High-res Image Gene #67: '16p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0425 (Fisher's exact test), Q value = 0.095
Table S364. Gene #67: '16p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 16P LOSS MUTATED | 7 | 1 | 2 |
| 16P LOSS WILD-TYPE | 166 | 208 | 126 |
Figure S364. Get High-res Image Gene #67: '16p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.019 (Fisher's exact test), Q value = 0.052
Table S365. Gene #68: '16q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 16Q LOSS MUTATED | 0 | 3 | 10 | 3 | 0 | 0 |
| 16Q LOSS WILD-TYPE | 61 | 77 | 146 | 79 | 80 | 69 |
Figure S365. Get High-res Image Gene #68: '16q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0317 (Fisher's exact test), Q value = 0.076
Table S366. Gene #68: '16q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 16Q LOSS MUTATED | 10 | 3 | 2 |
| 16Q LOSS WILD-TYPE | 163 | 206 | 126 |
Figure S366. Get High-res Image Gene #68: '16q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00021 (Fisher's exact test), Q value = 0.0011
Table S367. Gene #69: '17p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 17P LOSS MUTATED | 0 | 5 | 6 |
| 17P LOSS WILD-TYPE | 31 | 20 | 8 |
Figure S367. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.00097
Table S368. Gene #69: '17p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 17P LOSS MUTATED | 0 | 5 | 1 | 0 | 0 | 0 | 5 |
| 17P LOSS WILD-TYPE | 11 | 7 | 3 | 11 | 13 | 9 | 5 |
Figure S368. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0243 (Fisher's exact test), Q value = 0.062
Table S369. Gene #69: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 17P LOSS MUTATED | 3 | 6 | 20 | 1 | 9 | 7 |
| 17P LOSS WILD-TYPE | 58 | 74 | 136 | 81 | 71 | 62 |
Figure S369. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00056 (Fisher's exact test), Q value = 0.0027
Table S370. Gene #69: '17p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 17P LOSS MUTATED | 13 | 2 | 16 | 3 | 5 | 1 |
| 17P LOSS WILD-TYPE | 75 | 84 | 74 | 79 | 87 | 32 |
Figure S370. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00022
Table S371. Gene #69: '17p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 17P LOSS MUTATED | 6 | 11 | 19 | 4 |
| 17P LOSS WILD-TYPE | 129 | 101 | 66 | 135 |
Figure S371. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00015
Table S372. Gene #69: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 17P LOSS MUTATED | 14 | 2 | 7 | 21 | 2 |
| 17P LOSS WILD-TYPE | 67 | 168 | 74 | 132 | 38 |
Figure S372. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S373. Gene #69: '17p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 17P LOSS MUTATED | 6 | 3 | 3 | 23 | 2 | 9 |
| 17P LOSS WILD-TYPE | 111 | 30 | 180 | 109 | 33 | 16 |
Figure S373. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00015
Table S374. Gene #69: '17p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 17P LOSS MUTATED | 6 | 5 | 4 | 24 | 7 |
| 17P LOSS WILD-TYPE | 85 | 52 | 182 | 95 | 50 |
Figure S374. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00056
Table S375. Gene #69: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 17P LOSS MUTATED | 21 | 6 | 19 |
| 17P LOSS WILD-TYPE | 152 | 203 | 109 |
Figure S375. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00151 (Fisher's exact test), Q value = 0.0063
Table S376. Gene #70: '17q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 17Q LOSS MUTATED | 0 | 4 | 5 |
| 17Q LOSS WILD-TYPE | 31 | 21 | 9 |
Figure S376. Get High-res Image Gene #70: '17q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00052 (Fisher's exact test), Q value = 0.0026
Table S377. Gene #70: '17q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 17Q LOSS MUTATED | 0 | 4 | 0 | 0 | 0 | 0 | 5 |
| 17Q LOSS WILD-TYPE | 11 | 8 | 4 | 11 | 13 | 9 | 5 |
Figure S377. Get High-res Image Gene #70: '17q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00273 (Fisher's exact test), Q value = 0.011
Table S378. Gene #70: '17q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 17Q LOSS MUTATED | 3 | 5 | 11 | 3 |
| 17Q LOSS WILD-TYPE | 132 | 107 | 74 | 136 |
Figure S378. Get High-res Image Gene #70: '17q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-04 (Fisher's exact test), Q value = 6e-04
Table S379. Gene #70: '17q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 17Q LOSS MUTATED | 11 | 1 | 3 | 12 | 1 |
| 17Q LOSS WILD-TYPE | 70 | 169 | 78 | 141 | 39 |
Figure S379. Get High-res Image Gene #70: '17q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S380. Gene #70: '17q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 17Q LOSS MUTATED | 4 | 1 | 2 | 11 | 1 | 9 |
| 17Q LOSS WILD-TYPE | 113 | 32 | 181 | 121 | 34 | 16 |
Figure S380. Get High-res Image Gene #70: '17q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00031 (Fisher's exact test), Q value = 0.0016
Table S381. Gene #70: '17q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 17Q LOSS MUTATED | 4 | 2 | 2 | 14 | 6 |
| 17Q LOSS WILD-TYPE | 87 | 55 | 184 | 105 | 51 |
Figure S381. Get High-res Image Gene #70: '17q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00496 (Fisher's exact test), Q value = 0.018
Table S382. Gene #70: '17q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 17Q LOSS MUTATED | 9 | 5 | 14 |
| 17Q LOSS WILD-TYPE | 164 | 204 | 114 |
Figure S382. Get High-res Image Gene #70: '17q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00056 (Fisher's exact test), Q value = 0.0027
Table S383. Gene #71: '18p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 18P LOSS MUTATED | 9 | 16 | 43 | 5 | 13 | 7 |
| 18P LOSS WILD-TYPE | 52 | 64 | 113 | 77 | 67 | 62 |
Figure S383. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S384. Gene #71: '18p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 18P LOSS MUTATED | 8 | 20 | 27 | 2 |
| 18P LOSS WILD-TYPE | 59 | 50 | 69 | 79 |
Figure S384. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S385. Gene #71: '18p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 18P LOSS MUTATED | 13 | 4 | 37 | 15 | 11 | 3 |
| 18P LOSS WILD-TYPE | 75 | 82 | 53 | 67 | 81 | 30 |
Figure S385. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S386. Gene #71: '18p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 18P LOSS MUTATED | 10 | 33 | 25 | 15 |
| 18P LOSS WILD-TYPE | 125 | 79 | 60 | 124 |
Figure S386. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S387. Gene #71: '18p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 18P LOSS MUTATED | 11 | 7 | 12 | 60 | 2 |
| 18P LOSS WILD-TYPE | 70 | 163 | 69 | 93 | 38 |
Figure S387. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S388. Gene #71: '18p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 18P LOSS MUTATED | 10 | 5 | 9 | 55 | 10 | 3 |
| 18P LOSS WILD-TYPE | 107 | 28 | 174 | 77 | 25 | 22 |
Figure S388. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S389. Gene #71: '18p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 18P LOSS MUTATED | 18 | 17 | 9 | 43 | 6 |
| 18P LOSS WILD-TYPE | 73 | 40 | 177 | 76 | 51 |
Figure S389. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S390. Gene #71: '18p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 18P LOSS MUTATED | 43 | 12 | 38 |
| 18P LOSS WILD-TYPE | 130 | 197 | 90 |
Figure S390. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00084 (Fisher's exact test), Q value = 0.0038
Table S391. Gene #71: '18p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 18P LOSS MUTATED | 7 | 4 | 0 | 10 |
| 18P LOSS WILD-TYPE | 32 | 17 | 44 | 28 |
Figure S391. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00667 (Fisher's exact test), Q value = 0.022
Table S392. Gene #71: '18p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 40 | 52 | 28 | 22 |
| 18P LOSS MUTATED | 7 | 13 | 1 | 0 |
| 18P LOSS WILD-TYPE | 33 | 39 | 27 | 22 |
Figure S392. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00034 (Fisher's exact test), Q value = 0.0018
Table S393. Gene #72: '18q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 18Q LOSS MUTATED | 9 | 15 | 44 | 5 | 15 | 7 |
| 18Q LOSS WILD-TYPE | 52 | 65 | 112 | 77 | 65 | 62 |
Figure S393. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00039
Table S394. Gene #72: '18q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 18Q LOSS MUTATED | 8 | 20 | 25 | 4 |
| 18Q LOSS WILD-TYPE | 59 | 50 | 71 | 77 |
Figure S394. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S395. Gene #72: '18q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 18Q LOSS MUTATED | 14 | 6 | 37 | 14 | 12 | 3 |
| 18Q LOSS WILD-TYPE | 74 | 80 | 53 | 68 | 80 | 30 |
Figure S395. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00015
Table S396. Gene #72: '18q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 18Q LOSS MUTATED | 12 | 33 | 25 | 16 |
| 18Q LOSS WILD-TYPE | 123 | 79 | 60 | 123 |
Figure S396. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S397. Gene #72: '18q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 18Q LOSS MUTATED | 13 | 8 | 13 | 59 | 1 |
| 18Q LOSS WILD-TYPE | 68 | 162 | 68 | 94 | 39 |
Figure S397. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S398. Gene #72: '18q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 18Q LOSS MUTATED | 10 | 6 | 10 | 55 | 10 | 3 |
| 18Q LOSS WILD-TYPE | 107 | 27 | 173 | 77 | 25 | 22 |
Figure S398. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S399. Gene #72: '18q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 18Q LOSS MUTATED | 18 | 18 | 10 | 42 | 7 |
| 18Q LOSS WILD-TYPE | 73 | 39 | 176 | 77 | 50 |
Figure S399. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S400. Gene #72: '18q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 18Q LOSS MUTATED | 44 | 13 | 38 |
| 18Q LOSS WILD-TYPE | 129 | 196 | 90 |
Figure S400. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00927 (Fisher's exact test), Q value = 0.029
Table S401. Gene #72: '18q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 18Q LOSS MUTATED | 7 | 3 | 1 | 10 |
| 18Q LOSS WILD-TYPE | 32 | 18 | 43 | 28 |
Figure S401. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0322 (Fisher's exact test), Q value = 0.077
Table S402. Gene #72: '18q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 40 | 52 | 28 | 22 |
| 18Q LOSS MUTATED | 7 | 12 | 2 | 0 |
| 18Q LOSS WILD-TYPE | 33 | 40 | 26 | 22 |
Figure S402. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00022 (Fisher's exact test), Q value = 0.0012
Table S403. Gene #73: '19p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 19P LOSS MUTATED | 0 | 0 | 8 | 2 | 0 | 0 |
| 19P LOSS WILD-TYPE | 88 | 86 | 82 | 80 | 92 | 33 |
Figure S403. Get High-res Image Gene #73: '19p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00193 (Fisher's exact test), Q value = 0.0077
Table S404. Gene #73: '19p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 19P LOSS MUTATED | 0 | 3 | 6 | 1 |
| 19P LOSS WILD-TYPE | 135 | 109 | 79 | 138 |
Figure S404. Get High-res Image Gene #73: '19p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0113 (Fisher's exact test), Q value = 0.034
Table S405. Gene #73: '19p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 19P LOSS MUTATED | 1 | 0 | 1 | 9 | 0 | 0 |
| 19P LOSS WILD-TYPE | 116 | 33 | 182 | 123 | 35 | 25 |
Figure S405. Get High-res Image Gene #73: '19p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.027 (Fisher's exact test), Q value = 0.067
Table S406. Gene #73: '19p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 19P LOSS MUTATED | 2 | 0 | 1 | 7 | 1 |
| 19P LOSS WILD-TYPE | 89 | 57 | 185 | 112 | 56 |
Figure S406. Get High-res Image Gene #73: '19p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00537 (Fisher's exact test), Q value = 0.019
Table S407. Gene #73: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 19P LOSS MUTATED | 7 | 0 | 4 |
| 19P LOSS WILD-TYPE | 166 | 209 | 124 |
Figure S407. Get High-res Image Gene #73: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0237 (Fisher's exact test), Q value = 0.061
Table S408. Gene #75: '20p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 20P LOSS MUTATED | 2 | 1 | 0 | 5 | 0 |
| 20P LOSS WILD-TYPE | 89 | 56 | 186 | 114 | 57 |
Figure S408. Get High-res Image Gene #75: '20p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0328 (Fisher's exact test), Q value = 0.078
Table S409. Gene #77: '21q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 21Q LOSS MUTATED | 1 | 2 | 4 |
| 21Q LOSS WILD-TYPE | 30 | 23 | 10 |
Figure S409. Get High-res Image Gene #77: '21q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00069 (Fisher's exact test), Q value = 0.0033
Table S410. Gene #77: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 21Q LOSS MUTATED | 2 | 15 | 18 | 1 | 9 | 10 |
| 21Q LOSS WILD-TYPE | 59 | 65 | 138 | 81 | 71 | 59 |
Figure S410. Get High-res Image Gene #77: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 8e-04 (Fisher's exact test), Q value = 0.0037
Table S411. Gene #77: '21q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 21Q LOSS MUTATED | 11 | 7 | 19 | 8 | 3 | 0 |
| 21Q LOSS WILD-TYPE | 77 | 79 | 71 | 74 | 89 | 33 |
Figure S411. Get High-res Image Gene #77: '21q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00022
Table S412. Gene #77: '21q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 21Q LOSS MUTATED | 4 | 12 | 21 | 11 |
| 21Q LOSS WILD-TYPE | 131 | 100 | 64 | 128 |
Figure S412. Get High-res Image Gene #77: '21q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00081 (Fisher's exact test), Q value = 0.0037
Table S413. Gene #77: '21q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 21Q LOSS MUTATED | 19 | 10 | 4 | 17 | 3 |
| 21Q LOSS WILD-TYPE | 62 | 160 | 77 | 136 | 37 |
Figure S413. Get High-res Image Gene #77: '21q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00081
Table S414. Gene #77: '21q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 21Q LOSS MUTATED | 10 | 4 | 10 | 17 | 2 | 10 |
| 21Q LOSS WILD-TYPE | 107 | 29 | 173 | 115 | 33 | 15 |
Figure S414. Get High-res Image Gene #77: '21q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00046 (Fisher's exact test), Q value = 0.0023
Table S415. Gene #77: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 21Q LOSS MUTATED | 7 | 7 | 14 | 25 | 1 |
| 21Q LOSS WILD-TYPE | 84 | 50 | 172 | 94 | 56 |
Figure S415. Get High-res Image Gene #77: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0049 (Fisher's exact test), Q value = 0.017
Table S416. Gene #77: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 21Q LOSS MUTATED | 21 | 12 | 21 |
| 21Q LOSS WILD-TYPE | 152 | 197 | 107 |
Figure S416. Get High-res Image Gene #77: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0215 (Fisher's exact test), Q value = 0.056
Table S417. Gene #78: '22q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| 22Q LOSS MUTATED | 0 | 5 | 2 |
| 22Q LOSS WILD-TYPE | 31 | 20 | 12 |
Figure S417. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0013 (Fisher's exact test), Q value = 0.0056
Table S418. Gene #78: '22q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| 22Q LOSS MUTATED | 0 | 0 | 2 | 4 | 0 | 0 | 1 |
| 22Q LOSS WILD-TYPE | 11 | 12 | 2 | 7 | 13 | 9 | 9 |
Figure S418. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0175 (Fisher's exact test), Q value = 0.049
Table S419. Gene #78: '22q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| 22Q LOSS MUTATED | 2 | 9 | 19 | 5 | 3 | 1 |
| 22Q LOSS WILD-TYPE | 59 | 71 | 137 | 77 | 77 | 68 |
Figure S419. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00998 (Fisher's exact test), Q value = 0.031
Table S420. Gene #78: '22q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| 22Q LOSS MUTATED | 2 | 6 | 14 | 2 |
| 22Q LOSS WILD-TYPE | 65 | 64 | 82 | 79 |
Figure S420. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00041 (Fisher's exact test), Q value = 0.0021
Table S421. Gene #78: '22q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 88 | 86 | 90 | 82 | 92 | 33 |
| 22Q LOSS MUTATED | 6 | 4 | 19 | 3 | 4 | 1 |
| 22Q LOSS WILD-TYPE | 82 | 82 | 71 | 79 | 88 | 32 |
Figure S421. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0211 (Fisher's exact test), Q value = 0.056
Table S422. Gene #78: '22q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| 22Q LOSS MUTATED | 5 | 15 | 9 | 8 |
| 22Q LOSS WILD-TYPE | 130 | 97 | 76 | 131 |
Figure S422. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.4e-05
Table S423. Gene #78: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| 22Q LOSS MUTATED | 7 | 2 | 2 | 27 | 1 |
| 22Q LOSS WILD-TYPE | 74 | 168 | 79 | 126 | 39 |
Figure S423. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00015
Table S424. Gene #78: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| 22Q LOSS MUTATED | 6 | 6 | 3 | 21 | 3 | 0 |
| 22Q LOSS WILD-TYPE | 111 | 27 | 180 | 111 | 32 | 25 |
Figure S424. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 5e-05 (Fisher's exact test), Q value = 0.00034
Table S425. Gene #78: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| 22Q LOSS MUTATED | 3 | 7 | 6 | 21 | 2 |
| 22Q LOSS WILD-TYPE | 88 | 50 | 180 | 98 | 55 |
Figure S425. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00108 (Fisher's exact test), Q value = 0.0048
Table S426. Gene #78: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| 22Q LOSS MUTATED | 17 | 6 | 16 |
| 22Q LOSS WILD-TYPE | 156 | 203 | 112 |
Figure S426. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0384 (Fisher's exact test), Q value = 0.087
Table S427. Gene #78: '22q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 39 | 21 | 44 | 38 |
| 22Q LOSS MUTATED | 0 | 0 | 2 | 5 |
| 22Q LOSS WILD-TYPE | 39 | 21 | 42 | 33 |
Figure S427. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0261 (Fisher's exact test), Q value = 0.066
Table S428. Gene #79: 'xp loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| XP LOSS MUTATED | 3 | 1 | 5 |
| XP LOSS WILD-TYPE | 28 | 24 | 9 |
Figure S428. Get High-res Image Gene #79: 'xp loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0192 (Fisher's exact test), Q value = 0.052
Table S429. Gene #79: 'xp loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| XP LOSS MUTATED | 2 | 1 | 0 | 0 | 1 | 0 | 5 |
| XP LOSS WILD-TYPE | 9 | 11 | 4 | 11 | 12 | 9 | 5 |
Figure S429. Get High-res Image Gene #79: 'xp loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00021 (Fisher's exact test), Q value = 0.0011
Table S430. Gene #79: 'xp loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| XP LOSS MUTATED | 0 | 1 | 22 | 6 | 6 | 10 |
| XP LOSS WILD-TYPE | 61 | 79 | 134 | 76 | 74 | 59 |
Figure S430. Get High-res Image Gene #79: 'xp loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0228 (Fisher's exact test), Q value = 0.059
Table S431. Gene #79: 'xp loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| XP LOSS MUTATED | 6 | 3 | 15 | 3 |
| XP LOSS WILD-TYPE | 61 | 67 | 81 | 78 |
Figure S431. Get High-res Image Gene #79: 'xp loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00447 (Fisher's exact test), Q value = 0.016
Table S432. Gene #79: 'xp loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| XP LOSS MUTATED | 15 | 11 | 2 | 12 | 5 |
| XP LOSS WILD-TYPE | 66 | 159 | 79 | 141 | 35 |
Figure S432. Get High-res Image Gene #79: 'xp loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0214 (Fisher's exact test), Q value = 0.056
Table S433. Gene #79: 'xp loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| XP LOSS MUTATED | 9 | 1 | 12 | 11 | 5 | 7 |
| XP LOSS WILD-TYPE | 108 | 32 | 171 | 121 | 30 | 18 |
Figure S433. Get High-res Image Gene #79: 'xp loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00101 (Fisher's exact test), Q value = 0.0045
Table S434. Gene #79: 'xp loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| XP LOSS MUTATED | 10 | 12 | 22 |
| XP LOSS WILD-TYPE | 163 | 197 | 106 |
Figure S434. Get High-res Image Gene #79: 'xp loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0408 (Fisher's exact test), Q value = 0.092
Table S435. Gene #80: 'xq loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 31 | 25 | 14 |
| XQ LOSS MUTATED | 2 | 3 | 5 |
| XQ LOSS WILD-TYPE | 29 | 22 | 9 |
Figure S435. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0187 (Fisher's exact test), Q value = 0.051
Table S436. Gene #80: 'xq loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 11 | 12 | 4 | 11 | 13 | 9 | 10 |
| XQ LOSS MUTATED | 1 | 3 | 0 | 0 | 1 | 0 | 5 |
| XQ LOSS WILD-TYPE | 10 | 9 | 4 | 11 | 12 | 9 | 5 |
Figure S436. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 2e-04 (Fisher's exact test), Q value = 0.0011
Table S437. Gene #80: 'xq loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 61 | 80 | 156 | 82 | 80 | 69 |
| XQ LOSS MUTATED | 0 | 2 | 26 | 6 | 4 | 7 |
| XQ LOSS WILD-TYPE | 61 | 78 | 130 | 76 | 76 | 62 |
Figure S437. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00328 (Fisher's exact test), Q value = 0.013
Table S438. Gene #80: 'xq loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 67 | 70 | 96 | 81 |
| XQ LOSS MUTATED | 4 | 3 | 16 | 2 |
| XQ LOSS WILD-TYPE | 63 | 67 | 80 | 79 |
Figure S438. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.033 (Fisher's exact test), Q value = 0.078
Table S439. Gene #80: 'xq loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 135 | 112 | 85 | 139 |
| XQ LOSS MUTATED | 8 | 12 | 13 | 7 |
| XQ LOSS WILD-TYPE | 127 | 100 | 72 | 132 |
Figure S439. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0141 (Fisher's exact test), Q value = 0.041
Table S440. Gene #80: 'xq loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 81 | 170 | 81 | 153 | 40 |
| XQ LOSS MUTATED | 14 | 9 | 3 | 15 | 4 |
| XQ LOSS WILD-TYPE | 67 | 161 | 78 | 138 | 36 |
Figure S440. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0418 (Fisher's exact test), Q value = 0.094
Table S441. Gene #80: 'xq loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 117 | 33 | 183 | 132 | 35 | 25 |
| XQ LOSS MUTATED | 8 | 2 | 10 | 15 | 4 | 6 |
| XQ LOSS WILD-TYPE | 109 | 31 | 173 | 117 | 31 | 19 |
Figure S441. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0144 (Fisher's exact test), Q value = 0.042
Table S442. Gene #80: 'xq loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 91 | 57 | 186 | 119 | 57 |
| XQ LOSS MUTATED | 6 | 5 | 10 | 20 | 3 |
| XQ LOSS WILD-TYPE | 85 | 52 | 176 | 99 | 54 |
Figure S442. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00163 (Fisher's exact test), Q value = 0.0068
Table S443. Gene #80: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 173 | 209 | 128 |
| XQ LOSS MUTATED | 13 | 10 | 21 |
| XQ LOSS WILD-TYPE | 160 | 199 | 107 |
Figure S443. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
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Copy number data file = broad_values_by_arm.txt from GISTIC pipeline
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Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/KIRC-TP/22531285/transformed.cor.cli.txt
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Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/KIRC-TP/22555002/KIRC-TP.transferedmergedcluster.txt
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Number of patients = 528
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Number of significantly arm-level cnvs = 80
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Number of molecular subtypes = 12
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Exclude genes that fewer than K tumors have mutations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.