		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	24 (43%)	32	0.26311	0.818	0.59801	0.961	0.98212	1	0.79877	1	0.84611	1	0.90312	1	0.73793	0.998	0.36735	0.86	0.94713	1	0.67009	0.979
1q gain	31 (55%)	25	0.94132	1	0.24717	0.81	0.87211	1	0.63638	0.97	0.56283	0.946	0.61899	0.97	0.73726	0.998	0.52591	0.93	0.76391	1	0.91632	1
2p gain	23 (41%)	33	0.34882	0.86	0.10553	0.72	0.25296	0.81	0.03513	0.697	0.02637	0.688	0.057229	0.707	0.30422	0.836	0.072209	0.72	0.31143	0.836	0.13397	0.72
2q gain	21 (38%)	35	0.36136	0.86	0.10017	0.72	0.2111	0.809	0.31827	0.844	0.00107	0.45	0.11198	0.72	0.24488	0.81	0.04877	0.707	0.36443	0.86	0.11032	0.72
3p gain	10 (18%)	46	0.4102	0.864	0.79011	1	0.36284	0.86	0.29658	0.836	0.7928	1	0.24846	0.81	1	1	0.46742	0.886	0.71455	0.997	0.40818	0.863
3q gain	22 (39%)	34	0.10147	0.72	0.13186	0.72	0.38228	0.86	0.81189	1	0.45592	0.877	0.22824	0.81	0.21979	0.81	0.40867	0.863	0.81332	1	0.27035	0.825
4p gain	10 (18%)	46	0.21205	0.809	0.59561	0.961	0.01327	0.594	0.10082	0.72	0.6373	0.97	0.88349	1	0.40722	0.863	0.351	0.86	1	1	0.22975	0.81
4q gain	3 (5%)	53	0.17399	0.786	0.39171	0.86	NA	NA	NA	NA	0.388	0.86	0.79273	1	0.45713	0.877	0.56786	0.952	0.6925	0.991	0.69938	0.992
5p gain	23 (41%)	33	0.47925	0.897	0.21165	0.809	0.082129	0.72	0.19911	0.809	0.16482	0.786	0.24268	0.81	0.38842	0.86	0.02753	0.688	0.58315	0.957	0.14841	0.744
5q gain	8 (14%)	48	0.55207	0.944	0.51139	0.925	0.66829	0.978	0.20842	0.809	0.63295	0.97	0.24757	0.81	0.19724	0.809	0.1525	0.758	0.45448	0.877	0.19283	0.809
6p gain	31 (55%)	25	0.23123	0.81	0.34143	0.86	0.49727	0.918	0.39366	0.86	0.9328	1	0.32039	0.844	0.58087	0.957	0.17248	0.786	0.52278	0.93	0.066019	0.707
6q gain	27 (48%)	29	0.36096	0.86	0.23976	0.81	0.74147	0.998	0.62277	0.97	0.64896	0.97	0.1658	0.786	0.83514	1	0.18946	0.809	0.25424	0.81	0.13651	0.72
7p gain	21 (38%)	35	0.7793	1	0.39406	0.86	0.56077	0.946	0.29107	0.836	0.22313	0.81	0.27823	0.836	0.38267	0.86	0.12997	0.72	0.34221	0.86	0.12052	0.72
7q gain	18 (32%)	38	0.44263	0.877	0.80631	1	0.7313	0.998	0.60708	0.965	0.30675	0.836	0.65962	0.977	0.58296	0.957	0.1108	0.72	0.50828	0.925	0.063139	0.707
8p gain	18 (32%)	38	0.088209	0.72	0.31389	0.838	0.04107	0.698	0.17326	0.786	0.29565	0.836	0.77413	1	0.75498	1	0.3846	0.86	0.54966	0.944	0.23034	0.81
8q gain	30 (54%)	26	0.062039	0.707	0.1317	0.72	0.37957	0.86	0.59662	0.961	0.01016	0.573	0.50771	0.925	0.33324	0.859	0.32451	0.846	0.25717	0.81	0.12232	0.72
9p gain	6 (11%)	50	1	1	0.77879	1	0.50609	0.925	0.12118	0.72	0.93471	1	0.66485	0.977	0.8672	1	0.80351	1	0.78397	1	1	1
10p gain	20 (36%)	36	0.93909	1	0.58006	0.957	0.66397	0.977	0.54412	0.944	0.02623	0.688	0.25635	0.81	0.62636	0.97	0.30115	0.836	0.31929	0.844	0.43743	0.877
10q gain	17 (30%)	39	0.80896	1	0.88543	1	0.6282	0.97	0.46203	0.88	0.39275	0.86	0.04861	0.707	0.22121	0.81	0.18309	0.804	0.18972	0.809	0.073029	0.72
11p gain	5 (9%)	51	1	1	0.75753	1	0.7322	0.998	0.92502	1	0.28954	0.836	0.85381	1	1	1	0.11927	0.72	0.38158	0.86	0.092179	0.72
11q gain	7 (12%)	49	0.27198	0.826	0.95041	1	0.19346	0.809	0.71698	0.997	0.16035	0.786	0.37976	0.86	0.44746	0.877	0.03556	0.697	0.6793	0.985	0.03037	0.697
12p gain	22 (39%)	34	0.39458	0.86	0.01904	0.645	0.38214	0.86	0.59301	0.961	0.18287	0.804	0.04277	0.704	0.88255	1	0.97676	1	0.81257	1	0.62665	0.97
12q gain	11 (20%)	45	0.4386	0.877	0.53595	0.935	0.96566	1	0.85533	1	0.6274	0.97	0.52264	0.93	0.6865	0.988	0.29736	0.836	0.64225	0.97	0.26963	0.825
13q gain	15 (27%)	41	1	1	0.30624	0.836	0.094749	0.72	0.54496	0.944	0.03705	0.697	0.02447	0.688	0.0348	0.697	0.04606	0.707	0.059099	0.707	0.14081	0.72
14q gain	7 (12%)	49	0.45019	0.877	0.10627	0.72	0.43674	0.877	0.04988	0.707	0.20942	0.809	0.25932	0.811	0.25699	0.81	0.73527	0.998	0.11833	0.72	0.47274	0.889
15q gain	4 (7%)	52	0.34652	0.86	0.35248	0.86	0.22896	0.81	0.58114	0.957	0.40317	0.863	0.3293	0.856	0.053749	0.707	0.34614	0.86	0.57402	0.957	0.35592	0.86
16p gain	10 (18%)	46	0.0068199	0.45	0.7014	0.993	0.53385	0.935	0.82784	1	0.21736	0.81	0.27934	0.836	0.73948	0.998	0.48313	0.9	0.59141	0.961	0.40641	0.863
16q gain	6 (11%)	50	0.055459	0.707	0.48305	0.9	0.91937	1	0.92607	1	0.5134	0.926	0.96876	1	1	1	0.92488	1	1	1	0.86707	1
17p gain	9 (16%)	47	0.65103	0.97	0.62954	0.97	0.88587	1	0.82632	1	0.64638	0.97	0.56169	0.946	0.30115	0.836	0.061539	0.707	0.7633	1	0.17179	0.786
17q gain	18 (32%)	38	0.76691	1	0.74259	0.998	0.72418	0.998	0.80431	1	0.64825	0.97	0.51131	0.925	0.66554	0.977	0.30723	0.836	0.71084	0.997	0.42882	0.877
18p gain	18 (32%)	38	0.81917	1	0.34711	0.86	0.68549	0.988	0.7864	1	0.056839	0.707	0.34309	0.86	0.1188	0.72	0.19979	0.809	0.40485	0.863	0.43283	0.877
18q gain	13 (23%)	43	0.72943	0.998	0.94461	1	0.68321	0.988	0.60111	0.961	0.18106	0.804	0.29146	0.836	0.23608	0.81	0.17327	0.786	0.2512	0.81	0.28488	0.836
19p gain	24 (43%)	32	0.10698	0.72	0.52235	0.93	0.48556	0.903	0.77985	1	0.11756	0.72	0.18515	0.804	0.11497	0.72	0.03914	0.698	0.22048	0.81	0.13857	0.72
19q gain	29 (52%)	27	0.12092	0.72	0.68915	0.988	0.65786	0.977	0.87281	1	0.81012	1	0.43454	0.877	0.83424	1	0.77255	1	0.71632	0.997	0.97754	1
20p gain	36 (64%)	20	0.46022	0.878	0.73394	0.998	0.066129	0.707	0.47055	0.889	0.77854	1	0.72718	0.998	0.55427	0.944	0.35025	0.86	0.18593	0.804	0.20994	0.809
20q gain	43 (77%)	13	0.16841	0.786	0.74209	0.998	0.20687	0.809	0.71287	0.997	0.82897	1	0.95046	1	0.43957	0.877	0.2399	0.81	0.21366	0.809	0.39055	0.86
21q gain	18 (32%)	38	0.01503	0.594	0.11251	0.72	0.21409	0.809	0.78763	1	0.92252	1	0.89147	1	0.35258	0.86	0.57055	0.953	1	1	0.94705	1
22q gain	8 (14%)	48	0.48972	0.908	0.91505	1	0.52778	0.931	0.30451	0.836	0.76976	1	0.9267	1	0.89234	1	0.94315	1	0.94926	1	1	1
xp gain	18 (32%)	38	0.66661	0.977	0.03834	0.698	0.60222	0.961	0.34108	0.86	0.064369	0.707	0.4562	0.877	1	1	0.56004	0.946	0.27055	0.825	0.43432	0.877
xq gain	15 (27%)	41	0.86256	1	0.41672	0.872	0.88732	1	0.24595	0.81	0.52511	0.93	0.54166	0.943	0.17263	0.786	0.29185	0.836	0.086119	0.72	0.20271	0.809
1p loss	10 (18%)	46	0.40797	0.863	0.79082	1	0.94492	1	0.45603	0.877	0.84032	1	0.10086	0.72	0.03659	0.697	0.01392	0.594	0.51689	0.93	0.01458	0.594
1q loss	10 (18%)	46	0.24201	0.81	0.70394	0.995	0.64909	0.97	0.19733	0.809	0.69935	0.992	0.098309	0.72	0.13691	0.72	0.070339	0.72	0.41484	0.872	0.089389	0.72
3p loss	22 (39%)	34	0.44851	0.877	0.45233	0.877	0.43763	0.877	0.58282	0.957	0.01959	0.645	0.16739	0.786	0.72902	0.998	0.95326	1	0.67811	0.985	0.66349	0.977
3q loss	15 (27%)	41	0.20447	0.809	0.34737	0.86	0.50888	0.925	0.86229	1	0.065519	0.707	0.40699	0.863	0.16776	0.786	0.91134	1	0.97424	1	0.97007	1
4p loss	30 (54%)	26	0.12881	0.72	0.0091699	0.557	0.00427	0.45	0.075099	0.72	0.51812	0.93	0.44234	0.877	0.4221	0.873	0.63408	0.97	0.099019	0.72	0.45975	0.878
4q loss	34 (61%)	22	0.20471	0.809	0.00383	0.45	0.12045	0.72	0.20029	0.809	0.02478	0.688	0.056959	0.707	0.00361	0.45	0.20754	0.809	0.0050599	0.45	0.077429	0.72
5p loss	9 (16%)	47	1	1	0.25341	0.81	0.03484	0.697	0.062269	0.707	0.79597	1	0.1332	0.72	1	1	0.29805	0.836	1	1	0.4192	0.872
5q loss	18 (32%)	38	0.76509	1	0.11385	0.72	0.79421	1	0.079059	0.72	0.35536	0.86	0.23409	0.81	1	1	0.94788	1	0.5487	0.944	0.94782	1
6p loss	5 (9%)	51	0.22537	0.81	0.91778	1	0.13748	0.72	0.7515	1	0.80081	1	0.95684	1	1	1	0.91224	1	0.92307	1	1	1
6q loss	7 (12%)	49	0.082139	0.72	1	1	0.22583	0.81	0.13018	0.72	0.44868	0.877	0.92124	1	1	1	0.9363	1	0.62569	0.97	0.93448	1
7p loss	13 (23%)	43	0.51152	0.925	0.70769	0.997	0.26558	0.823	0.28859	0.836	0.6779	0.985	0.49836	0.918	0.8497	1	0.45535	0.877	0.47573	0.893	0.59844	0.961
7q loss	12 (21%)	44	0.13411	0.72	0.97042	1	0.5857	0.957	0.61812	0.97	0.96873	1	0.94358	1	0.65011	0.97	0.30849	0.836	0.46321	0.88	0.55393	0.944
8p loss	24 (43%)	32	0.04154	0.698	0.94757	1	0.41957	0.872	0.13833	0.72	0.91539	1	0.61903	0.97	1	1	0.36707	0.86	0.94694	1	0.34843	0.86
8q loss	9 (16%)	47	0.37118	0.86	0.67421	0.983	0.81216	1	0.68809	0.988	0.03993	0.698	0.71226	0.997	0.89684	1	0.75666	1	1	1	0.66569	0.977
9p loss	35 (62%)	21	0.11167	0.72	0.27006	0.825	0.0068299	0.45	0.00217	0.45	0.64443	0.97	0.21276	0.809	0.58722	0.957	0.38243	0.86	0.31873	0.844	0.091939	0.72
9q loss	40 (71%)	16	0.066189	0.707	0.30943	0.836	0.080129	0.72	0.065759	0.707	0.87418	1	0.058789	0.707	0.68816	0.988	0.22305	0.81	0.73034	0.998	0.25246	0.81
10p loss	24 (43%)	32	0.61851	0.97	0.03663	0.697	0.71703	0.997	0.8057	1	0.0178	0.645	0.22427	0.81	1	1	1	1	0.88641	1	0.97601	1
10q loss	20 (36%)	36	0.93744	1	0.44666	0.877	0.42753	0.877	0.78284	1	0.38572	0.86	0.25739	0.81	0.63	0.97	0.58759	0.957	0.35419	0.86	0.82393	1
11p loss	28 (50%)	28	0.78553	1	0.02534	0.688	0.60512	0.964	0.88966	1	0.7325	0.998	0.31225	0.836	0.33412	0.859	0.39052	0.86	0.32289	0.845	0.23116	0.81
11q loss	26 (46%)	30	0.13723	0.72	0.43551	0.877	0.11511	0.72	0.91015	1	0.84511	1	0.5353	0.935	0.37731	0.86	0.52609	0.93	0.24903	0.81	0.13714	0.72
12p loss	13 (23%)	43	0.37548	0.86	0.64831	0.97	0.2841	0.836	0.74269	0.998	0.72092	0.998	0.73403	0.998	0.78337	1	0.57768	0.957	0.77481	1	0.2171	0.81
12q loss	14 (25%)	42	0.30709	0.836	0.97267	1	0.41865	0.872	0.12506	0.72	0.88291	1	0.91614	1	1	1	0.90744	1	0.3952	0.86	0.60204	0.961
13q loss	26 (46%)	30	0.51958	0.93	0.070189	0.72	0.3042	0.836	0.14883	0.744	0.097889	0.72	0.02785	0.688	0.4004	0.863	0.11782	0.72	0.13043	0.72	0.19859	0.809
14q loss	27 (48%)	29	0.94212	1	0.17414	0.786	0.86564	1	0.11731	0.72	0.1066	0.72	0.12446	0.72	0.38208	0.86	0.89837	1	0.28451	0.836	0.93835	1
15q loss	33 (59%)	23	0.01109	0.584	0.34659	0.86	0.90262	1	0.12597	0.72	1	1	0.97967	1	1	1	0.95321	1	0.87826	1	0.90954	1
16p loss	32 (57%)	24	0.42106	0.873	0.82339	1	0.40399	0.863	0.086019	0.72	0.32192	0.845	0.098949	0.72	0.36985	0.86	0.91524	1	0.86888	1	0.89572	1
16q loss	37 (66%)	19	0.36937	0.86	0.37287	0.86	0.25045	0.81	0.12904	0.72	0.64514	0.97	0.090339	0.72	0.14118	0.72	0.92182	1	0.88178	1	0.85854	1
17p loss	34 (61%)	22	0.44497	0.877	0.34515	0.86	0.0196	0.645	0.27403	0.829	0.9267	1	0.75894	1	0.93933	1	0.89106	1	0.44411	0.877	0.88902	1
17q loss	17 (30%)	39	0.65863	0.977	0.55335	0.944	0.13178	0.72	0.62804	0.97	0.69462	0.991	0.38457	0.86	0.25959	0.811	0.21234	0.809	0.73828	0.998	0.27647	0.834
18p loss	18 (32%)	38	0.47282	0.889	0.25209	0.81	0.55888	0.946	0.29141	0.836	0.0469	0.707	0.090019	0.72	0.03206	0.697	0.078889	0.72	0.081569	0.72	0.04642	0.707
18q loss	20 (36%)	36	0.14666	0.743	0.5971	0.961	0.29754	0.836	0.29706	0.836	0.24606	0.81	0.11994	0.72	0.00142	0.45	0.0055299	0.45	0.065389	0.707	0.00255	0.45
19p loss	15 (27%)	41	0.55017	0.944	0.14126	0.72	0.1577	0.779	0.38033	0.86	0.01269	0.594	0.061329	0.707	0.16616	0.786	0.254	0.81	0.090589	0.72	0.18635	0.804
19q loss	12 (21%)	44	0.64995	0.97	0.62884	0.97	0.1054	0.72	0.816	1	0.84243	1	0.50833	0.925	0.40795	0.863	0.96116	1	0.56951	0.953	1	1
20p loss	8 (14%)	48	0.88889	1	0.58728	0.957	0.53205	0.935	0.0062699	0.45	0.1798	0.802	0.28524	0.836	0.55679	0.946	0.335	0.859	0.8383	1	0.39493	0.86
20q loss	5 (9%)	51	0.43372	0.877	0.80618	1	0.78624	1	0.2411	0.81	0.53587	0.935	0.91078	1	0.71047	0.997	0.69371	0.991	1	1	0.62733	0.97
21q loss	17 (30%)	39	0.43124	0.877	0.077609	0.72	0.056659	0.707	0.33046	0.856	0.49142	0.909	0.74747	1	0.80715	1	0.9725	1	1	1	0.94209	1
22q loss	33 (59%)	23	0.94198	1	0.89906	1	0.39422	0.86	0.02172	0.686	0.77947	1	0.90121	1	0.17857	0.802	0.29047	0.836	0.94459	1	0.75884	1
xp loss	15 (27%)	41	0.19121	0.809	0.69808	0.992	0.92414	1	0.16996	0.786	0.95229	1	0.85893	1	0.54723	0.944	0.64662	0.97	0.82875	1	0.76107	1
xq loss	18 (32%)	38	0.76625	1	0.85367	1	0.86828	1	0.03407	0.697	0.42808	0.877	0.6237	0.97	0.31097	0.836	0.64713	0.97	0.13678	0.72	0.75202	1
