Correlation between gene mutation status and molecular subtypes

Adrenocortical Carcinoma (Primary solid tumor)

28 January 2016 | analyses__2016_01_28

Maintainer Information

Citation Information

Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)

Cite as Broad Institute TCGA Genome Data Analysis Center (2016): Correlation between gene mutation status and molecular subtypes. Broad Institute of MIT and Harvard. doi:10.7908/C1K64HDH

Overview

Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 116 genes and 10 molecular subtypes across 62 patients, no significant finding detected with P value < 0.05 and Q value < 0.25.

No gene mutations related to molecuar subtypes.

Results

Overview of the results

Table 1. Get Full Table Overview of the association between mutation status of 116 genes and 10 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, no significant finding detected.


		Clinical Features	CN CNMF	METHLYATION CNMF	RPPA CNMF	RPPA CHIERARCHICAL	MRNASEQ CNMF	MRNASEQ CHIERARCHICAL	MIRSEQ CNMF	MIRSEQ CHIERARCHICAL	MIRSEQ MATURE CNMF	MIRSEQ MATURE CHIERARCHICAL
	nMutated (%)	nWild-Type	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test
ZFPM1	24 (39%)	38	0.433 (1.00)	0.0988 (1.00)	0.375 (1.00)	0.872 (1.00)	0.24 (1.00)	0.747 (1.00)	0.61 (1.00)	0.921 (1.00)	0.742 (1.00)	0.535 (1.00)
LACTB	19 (31%)	43	0.0741 (1.00)	0.375 (1.00)	0.893 (1.00)	0.57 (1.00)	1 (1.00)	0.315 (1.00)	0.934 (1.00)	0.75 (1.00)	0.64 (1.00)	0.34 (1.00)
CCDC102A	17 (27%)	45	0.66 (1.00)	0.59 (1.00)	1 (1.00)	0.505 (1.00)	0.976 (1.00)	0.825 (1.00)	0.498 (1.00)	0.469 (1.00)	0.261 (1.00)	0.439 (1.00)
ZNF517	13 (21%)	49	0.945 (1.00)	0.734 (1.00)			0.823 (1.00)	0.952 (1.00)	0.275 (1.00)	0.694 (1.00)	0.861 (1.00)	0.461 (1.00)
MAL2	11 (18%)	51	0.915 (1.00)	0.0795 (1.00)	0.285 (1.00)	1 (1.00)	0.314 (1.00)	0.511 (1.00)	0.707 (1.00)	0.267 (1.00)	0.812 (1.00)	0.506 (1.00)
TOR3A	12 (19%)	50	0.19 (1.00)	0.307 (1.00)	0.112 (1.00)	0.313 (1.00)	0.556 (1.00)	0.00508 (1)	1 (1.00)	0.842 (1.00)	0.626 (1.00)	0.666 (1.00)
TP53	13 (21%)	49	0.141 (1.00)	0.346 (1.00)	0.275 (1.00)	0.601 (1.00)	0.0299 (1.00)	0.322 (1.00)	0.0243 (1.00)	0.596 (1.00)	0.0332 (1.00)	0.0834 (1.00)
CLDN23	10 (16%)	52	0.225 (1.00)	0.403 (1.00)	1 (1.00)	0.348 (1.00)	0.0353 (1.00)	0.212 (1.00)	0.345 (1.00)	0.181 (1.00)	0.507 (1.00)	0.307 (1.00)
GDF1	5 (8%)	57	0.0265 (1.00)	0.14 (1.00)			0.442 (1.00)	0.354 (1.00)	0.238 (1.00)	0.511 (1.00)	0.473 (1.00)	0.605 (1.00)
LZTR1	6 (10%)	56	0.021 (1.00)	0.943 (1.00)			0.132 (1.00)	0.117 (1.00)	0.183 (1.00)	0.0147 (1.00)	0.387 (1.00)	0.0661 (1.00)
ANKRD43	19 (31%)	43	0.377 (1.00)	0.174 (1.00)	0.481 (1.00)	0.599 (1.00)	0.268 (1.00)	0.226 (1.00)	0.565 (1.00)	0.103 (1.00)	0.521 (1.00)	0.596 (1.00)
KCNK17	9 (15%)	53	0.156 (1.00)	0.0103 (1)	0.376 (1.00)	0.44 (1.00)	0.074 (1.00)	0.00953 (1)	0.797 (1.00)	0.546 (1.00)	0.405 (1.00)	0.567 (1.00)
RINL	8 (13%)	54	0.326 (1.00)	0.962 (1.00)	0.0749 (1.00)	0.579 (1.00)	0.476 (1.00)	0.275 (1.00)	0.268 (1.00)	0.169 (1.00)	0.098 (1.00)	0.362 (1.00)
ZAR1	11 (18%)	51	0.209 (1.00)	0.298 (1.00)	0.229 (1.00)	0.793 (1.00)	0.507 (1.00)	0.87 (1.00)	0.428 (1.00)	0.97 (1.00)	0.3 (1.00)	0.701 (1.00)
CTNNB1	8 (13%)	54	0.641 (1.00)	0.32 (1.00)	0.112 (1.00)	0.313 (1.00)	0.00852 (1)	0.00605 (1)	0.00525 (1)	0.167 (1.00)	0.0429 (1.00)	0.403 (1.00)
APOE	7 (11%)	55	0.111 (1.00)	0.707 (1.00)	0.467 (1.00)	0.383 (1.00)	0.0376 (1.00)	0.4 (1.00)	0.652 (1.00)	0.79 (1.00)	0.171 (1.00)	0.921 (1.00)
GPRIN2	8 (13%)	54	0.526 (1.00)	0.178 (1.00)	0.227 (1.00)	0.692 (1.00)	0.745 (1.00)	0.4 (1.00)	0.88 (1.00)	0.753 (1.00)	0.627 (1.00)	0.502 (1.00)
ASPDH	8 (13%)	54	0.282 (1.00)	0.299 (1.00)	0.713 (1.00)	0.314 (1.00)	0.00903 (1)	0.398 (1.00)	0.314 (1.00)	0.0324 (1.00)	0.0702 (1.00)	0.0148 (1.00)
ERCC2	10 (16%)	52	0.214 (1.00)	0.117 (1.00)	0.0954 (1.00)	0.233 (1.00)	0.509 (1.00)	0.172 (1.00)	0.381 (1.00)	0.268 (1.00)	0.38 (1.00)	0.489 (1.00)
IDUA	8 (13%)	54	0.0199 (1.00)	0.526 (1.00)	0.818 (1.00)	0.791 (1.00)	0.571 (1.00)	0.546 (1.00)	0.687 (1.00)	0.432 (1.00)	0.819 (1.00)	0.476 (1.00)
C1ORF106	9 (15%)	53	0.406 (1.00)	0.497 (1.00)	0.265 (1.00)	0.0481 (1.00)	0.412 (1.00)	0.762 (1.00)	0.627 (1.00)	0.691 (1.00)	0.599 (1.00)	0.988 (1.00)
C10ORF95	6 (10%)	56	0.237 (1.00)	0.691 (1.00)			0.606 (1.00)	1 (1.00)	0.61 (1.00)	0.359 (1.00)	0.772 (1.00)	0.783 (1.00)
RGS9BP	8 (13%)	54	0.202 (1.00)	0.578 (1.00)	0.879 (1.00)	0.128 (1.00)	1 (1.00)	0.935 (1.00)	0.236 (1.00)	0.963 (1.00)	0.561 (1.00)	0.254 (1.00)
THEM4	5 (8%)	57	0.124 (1.00)	0.214 (1.00)			0.441 (1.00)	0.876 (1.00)	0.539 (1.00)	0.107 (1.00)	0.513 (1.00)	0.304 (1.00)
TSC22D2	8 (13%)	54	0.66 (1.00)	0.265 (1.00)	0.674 (1.00)	0.955 (1.00)	0.683 (1.00)	0.817 (1.00)	0.878 (1.00)	0.43 (1.00)	0.625 (1.00)	0.671 (1.00)
SYT8	8 (13%)	54	0.174 (1.00)	0.305 (1.00)	0.468 (1.00)	1 (1.00)	0.0644 (1.00)	0.175 (1.00)	1 (1.00)	0.184 (1.00)	0.633 (1.00)	0.705 (1.00)
PLIN5	5 (8%)	57	0.896 (1.00)	0.753 (1.00)	0.309 (1.00)	0.382 (1.00)	0.797 (1.00)	0.667 (1.00)	0.721 (1.00)	0.266 (1.00)	0.857 (1.00)	0.312 (1.00)
LRIG1	16 (26%)	46	0.448 (1.00)	0.649 (1.00)	0.283 (1.00)	1 (1.00)	0.871 (1.00)	0.611 (1.00)	0.586 (1.00)	0.432 (1.00)	0.694 (1.00)	0.985 (1.00)
HHIPL1	6 (10%)	56	0.151 (1.00)	0.576 (1.00)			0.566 (1.00)	0.512 (1.00)	0.36 (1.00)	0.425 (1.00)	0.0508 (1.00)	0.298 (1.00)
CCDC105	6 (10%)	56	0.837 (1.00)	0.0763 (1.00)	0.466 (1.00)	0.673 (1.00)	0.933 (1.00)	0.793 (1.00)	0.865 (1.00)	0.0546 (1.00)	0.333 (1.00)	0.153 (1.00)
C19ORF10	7 (11%)	55	0.76 (1.00)	0.231 (1.00)	0.819 (1.00)	0.392 (1.00)	0.29 (1.00)	0.125 (1.00)	0.656 (1.00)	0.865 (1.00)	0.348 (1.00)	0.862 (1.00)
OPRD1	12 (19%)	50	0.907 (1.00)	0.582 (1.00)	0.229 (1.00)	0.481 (1.00)	0.826 (1.00)	0.96 (1.00)	0.494 (1.00)	0.615 (1.00)	0.505 (1.00)	0.525 (1.00)
ATXN1	10 (16%)	52	0.45 (1.00)	0.0295 (1.00)	0.148 (1.00)	0.916 (1.00)	0.14 (1.00)	0.656 (1.00)	0.429 (1.00)	0.87 (1.00)	0.0468 (1.00)	0.594 (1.00)
AATK	6 (10%)	56	0.0984 (1.00)	0.316 (1.00)			0.225 (1.00)	0.355 (1.00)	1 (1.00)	0.545 (1.00)	0.771 (1.00)	0.741 (1.00)
ZNF628	7 (11%)	55	0.779 (1.00)	0.85 (1.00)	1 (1.00)	0.675 (1.00)	0.281 (1.00)	0.113 (1.00)	0.499 (1.00)	0.503 (1.00)	0.15 (1.00)	0.67 (1.00)
KRTAP4-5	5 (8%)	57	0.77 (1.00)	0.824 (1.00)			0.905 (1.00)	0.876 (1.00)	1 (1.00)	0.842 (1.00)	1 (1.00)	0.965 (1.00)
NOXA1	5 (8%)	57	0.155 (1.00)	0.741 (1.00)			0.24 (1.00)	0.442 (1.00)	0.103 (1.00)	0.35 (1.00)	0.193 (1.00)	0.154 (1.00)
TRIOBP	10 (16%)	52	0.905 (1.00)	0.419 (1.00)	0.464 (1.00)	0.129 (1.00)	1 (1.00)	0.111 (1.00)	0.533 (1.00)	0.869 (1.00)	0.457 (1.00)	0.891 (1.00)
ZNF598	12 (19%)	50	0.649 (1.00)	0.773 (1.00)	0.586 (1.00)	0.748 (1.00)	0.823 (1.00)	0.952 (1.00)	0.901 (1.00)	0.227 (1.00)	0.177 (1.00)	0.25 (1.00)
IRX3	5 (8%)	57	0.317 (1.00)	0.436 (1.00)			0.532 (1.00)	0.118 (1.00)	0.54 (1.00)	0.781 (1.00)	0.17 (1.00)	0.0829 (1.00)
WDR34	5 (8%)	57	0.194 (1.00)	0.898 (1.00)			0.858 (1.00)	0.816 (1.00)	0.606 (1.00)	0.551 (1.00)	0.223 (1.00)	0.0972 (1.00)
BHLHE22	5 (8%)	57	0.943 (1.00)	0.294 (1.00)	0.816 (1.00)	0.916 (1.00)	0.0459 (1.00)	0.812 (1.00)	1 (1.00)	0.835 (1.00)	0.593 (1.00)	0.817 (1.00)
PANK2	5 (8%)	57	0.768 (1.00)	0.795 (1.00)	0.586 (1.00)	0.348 (1.00)	0.0793 (1.00)	0.05 (1.00)	0.767 (1.00)	0.351 (1.00)	0.0176 (1.00)	0.305 (1.00)
FPGS	5 (8%)	57	0.573 (1.00)	0.0904 (1.00)	0.468 (1.00)	0.349 (1.00)	0.686 (1.00)	0.598 (1.00)	0.238 (1.00)	0.625 (1.00)	0.659 (1.00)	0.88 (1.00)
GLTPD2	6 (10%)	56	0.0989 (1.00)	0.826 (1.00)			0.83 (1.00)	0.399 (1.00)	0.866 (1.00)	0.533 (1.00)	0.334 (1.00)	0.228 (1.00)
TNIP2	5 (8%)	57	0.845 (1.00)	0.425 (1.00)			0.746 (1.00)	0.875 (1.00)	0.823 (1.00)	0.413 (1.00)	0.608 (1.00)	0.265 (1.00)
AKAP2	6 (10%)	56	0.0709 (1.00)	0.824 (1.00)	0.917 (1.00)	0.755 (1.00)	0.829 (1.00)	0.593 (1.00)	0.656 (1.00)	0.281 (1.00)	0.94 (1.00)	0.707 (1.00)
RREB1	5 (8%)	57	0.278 (1.00)	0.86 (1.00)			0.619 (1.00)	1 (1.00)	0.236 (1.00)	0.546 (1.00)	0.286 (1.00)	0.489 (1.00)
TPO	12 (19%)	50	0.283 (1.00)	0.527 (1.00)	0.886 (1.00)	0.693 (1.00)	0.221 (1.00)	0.125 (1.00)	0.221 (1.00)	0.342 (1.00)	0.477 (1.00)	0.195 (1.00)
OBSCN	18 (29%)	44	0.963 (1.00)	0.34 (1.00)	0.891 (1.00)	0.545 (1.00)	0.568 (1.00)	0.808 (1.00)	0.219 (1.00)	0.497 (1.00)	0.956 (1.00)	0.563 (1.00)
SNED1	5 (8%)	57	0.316 (1.00)	0.899 (1.00)			0.439 (1.00)	0.668 (1.00)	0.0327 (1.00)	0.662 (1.00)	0.298 (1.00)	0.88 (1.00)
MEN1	5 (8%)	57	0.285 (1.00)	0.0178 (1.00)			0.0189 (1.00)	0.00659 (1)	0.174 (1.00)	0.0428 (1.00)	0.0241 (1.00)	0.0755 (1.00)
BTBD11	6 (10%)	56	1 (1.00)	0.884 (1.00)			0.798 (1.00)	1 (1.00)	0.174 (1.00)	0.184 (1.00)	0.343 (1.00)	0.237 (1.00)
RNF149	4 (6%)	58	0.215 (1.00)	0.0608 (1.00)	0.675 (1.00)	0.954 (1.00)	0.439 (1.00)	0.601 (1.00)	0.822 (1.00)	0.26 (1.00)	0.606 (1.00)	0.553 (1.00)
KIAA1984	4 (6%)	58	0.149 (1.00)	0.117 (1.00)	1 (1.00)	0.506 (1.00)	0.103 (1.00)	0.0496 (1.00)	0.18 (1.00)	0.584 (1.00)	0.389 (1.00)	0.967 (1.00)
CCDC150	4 (6%)	58	0.537 (1.00)	0.581 (1.00)	1 (1.00)	0.602 (1.00)	0.178 (1.00)	0.117 (1.00)	0.535 (1.00)	0.21 (1.00)	0.169 (1.00)	0.299 (1.00)
FAM18B2	4 (6%)	58	0.23 (1.00)	0.966 (1.00)			0.223 (1.00)	0.481 (1.00)	0.0973 (1.00)	0.51 (1.00)	0.0286 (1.00)	0.603 (1.00)
MUC5B	22 (35%)	40	0.997 (1.00)	0.133 (1.00)	0.538 (1.00)	0.812 (1.00)	0.77 (1.00)	0.67 (1.00)	0.936 (1.00)	0.617 (1.00)	0.874 (1.00)	0.967 (1.00)
PTPLA	4 (6%)	58	0.231 (1.00)	0.444 (1.00)			0.617 (1.00)	0.441 (1.00)	1 (1.00)	1 (1.00)	0.193 (1.00)	0.497 (1.00)
SRPX	3 (5%)	59	0.661 (1.00)	0.444 (1.00)			0.617 (1.00)	1 (1.00)	1 (1.00)	0.718 (1.00)	1 (1.00)	0.849 (1.00)
GARS	19 (31%)	43	0.431 (1.00)	0.228 (1.00)	0.517 (1.00)	0.335 (1.00)	0.308 (1.00)	0.102 (1.00)	0.0744 (1.00)	0.403 (1.00)	0.174 (1.00)	0.484 (1.00)
PRSS27	3 (5%)	59	0.0865 (1.00)	0.74 (1.00)			0.127 (1.00)	0.0502 (1.00)	0.499 (1.00)	1 (1.00)	0.69 (1.00)	0.493 (1.00)
SEMA5B	8 (13%)	54	0.128 (1.00)	0.534 (1.00)	0.588 (1.00)	0.175 (1.00)	0.461 (1.00)	0.214 (1.00)	0.486 (1.00)	0.298 (1.00)	0.444 (1.00)	0.603 (1.00)
CD320	4 (6%)	58	0.968 (1.00)	1 (1.00)			1 (1.00)	0.654 (1.00)	0.367 (1.00)	0.225 (1.00)	0.111 (1.00)	0.227 (1.00)
TAF5	4 (6%)	58	0.967 (1.00)	1 (1.00)	0.31 (1.00)	0.954 (1.00)	1 (1.00)	0.876 (1.00)	0.0995 (1.00)	0.115 (1.00)	0.469 (1.00)	0.167 (1.00)
NEFH	6 (10%)	56	0.64 (1.00)	0.366 (1.00)			0.0792 (1.00)	0.051 (1.00)	0.535 (1.00)	0.211 (1.00)	0.00318 (1)	0.182 (1.00)
DMKN	3 (5%)	59	0.0997 (1.00)	0.441 (1.00)			0.617 (1.00)	0.443 (1.00)	0.0512 (1.00)	0.571 (1.00)	0.12 (1.00)	0.893 (1.00)
NPTX1	3 (5%)	59	0.256 (1.00)	0.55 (1.00)			1 (1.00)	0.812 (1.00)	0.277 (1.00)	0.796 (1.00)	0.485 (1.00)	0.762 (1.00)
NOTCH2	5 (8%)	57	0.0315 (1.00)	0.823 (1.00)			0.528 (1.00)	0.119 (1.00)	0.014 (1.00)	0.319 (1.00)	0.0287 (1.00)	0.554 (1.00)
RNF39	5 (8%)	57	0.788 (1.00)	0.411 (1.00)	0.0744 (1.00)	0.794 (1.00)	0.146 (1.00)	0.263 (1.00)	0.359 (1.00)	0.703 (1.00)	0.385 (1.00)	0.509 (1.00)
KBTBD13	9 (15%)	53	0.768 (1.00)	0.403 (1.00)	0.489 (1.00)	0.793 (1.00)	0.709 (1.00)	0.118 (1.00)	0.534 (1.00)	0.331 (1.00)	0.661 (1.00)	0.905 (1.00)
IER5	3 (5%)	59	0.259 (1.00)
SCRT1	3 (5%)	59	0.942 (1.00)	0.593 (1.00)			0.468 (1.00)	0.618 (1.00)	0.768 (1.00)	0.795 (1.00)	0.369 (1.00)	1 (1.00)
KNDC1	9 (15%)	53	0.669 (1.00)	0.0158 (1.00)	0.586 (1.00)	0.555 (1.00)	0.041 (1.00)	0.327 (1.00)	0.516 (1.00)	0.365 (1.00)	0.362 (1.00)	0.549 (1.00)
MAP1S	5 (8%)	57	0.516 (1.00)	0.364 (1.00)	0.285 (1.00)	0.417 (1.00)	0.444 (1.00)	1 (1.00)	1 (1.00)	0.836 (1.00)	1 (1.00)	0.816 (1.00)
RGMB	6 (10%)	56	0.367 (1.00)
LRP11	6 (10%)	56	0.321 (1.00)	0.388 (1.00)			0.798 (1.00)	0.666 (1.00)	1 (1.00)	0.936 (1.00)	0.924 (1.00)	0.595 (1.00)
AR	4 (6%)	58	0.308 (1.00)	0.282 (1.00)	1 (1.00)	0.954 (1.00)	0.467 (1.00)	0.444 (1.00)	0.771 (1.00)	1 (1.00)	0.192 (1.00)	1 (1.00)
VARS	6 (10%)	56	0.544 (1.00)	0.359 (1.00)	0.311 (1.00)	0.381 (1.00)	0.483 (1.00)	0.0677 (1.00)	1 (1.00)	0.861 (1.00)	0.836 (1.00)	1 (1.00)
SEZ6L2	8 (13%)	54	0.656 (1.00)	0.143 (1.00)	0.88 (1.00)	0.788 (1.00)	0.831 (1.00)	1 (1.00)	0.866 (1.00)	0.628 (1.00)	1 (1.00)	0.576 (1.00)
PABPC1	4 (6%)	58	0.331 (1.00)
FANK1	3 (5%)	59	1 (1.00)	0.0518 (1.00)			0.866 (1.00)	0.288 (1.00)	0.279 (1.00)	0.232 (1.00)	0.28 (1.00)	0.0367 (1.00)
NMU	5 (8%)	57	0.332 (1.00)	0.841 (1.00)			0.125 (1.00)	0.617 (1.00)	0.823 (1.00)	0.545 (1.00)	1 (1.00)	0.16 (1.00)
ADAD2	4 (6%)	58	0.191 (1.00)	0.48 (1.00)			0.746 (1.00)	0.173 (1.00)	0.0979 (1.00)	0.51 (1.00)	0.469 (1.00)	0.879 (1.00)
CLIC6	5 (8%)	57	0.228 (1.00)	0.434 (1.00)			0.685 (1.00)	0.118 (1.00)	0.185 (1.00)	0.584 (1.00)	0.0487 (1.00)	0.967 (1.00)
PCDHB13	5 (8%)	57	0.529 (1.00)	0.0281 (1.00)			0.441 (1.00)	0.356 (1.00)	0.37 (1.00)	0.0596 (1.00)	0.129 (1.00)	0.0957 (1.00)
PLEC	13 (21%)	49	0.688 (1.00)	0.202 (1.00)	0.111 (1.00)	0.0472 (1.00)	0.141 (1.00)	0.72 (1.00)	0.625 (1.00)	0.632 (1.00)	0.35 (1.00)	0.0626 (1.00)
AMDHD1	10 (16%)	52	0.284 (1.00)	0.67 (1.00)	1 (1.00)	0.35 (1.00)	0.591 (1.00)	0.136 (1.00)	0.73 (1.00)	0.853 (1.00)	0.541 (1.00)	0.88 (1.00)
DSPP	9 (15%)	53	0.12 (1.00)	0.159 (1.00)	0.23 (1.00)	0.692 (1.00)	1 (1.00)	0.483 (1.00)	0.729 (1.00)	0.54 (1.00)	0.427 (1.00)	0.355 (1.00)
TMEM189	3 (5%)	59	0.783 (1.00)
CRIPAK	10 (16%)	52	0.13 (1.00)	0.53 (1.00)	0.819 (1.00)	0.934 (1.00)	0.423 (1.00)	0.69 (1.00)	0.35 (1.00)	0.328 (1.00)	0.493 (1.00)	0.446 (1.00)
PDCD6	3 (5%)	59	0.606 (1.00)	0.643 (1.00)					1 (1.00)	0.639 (1.00)	1 (1.00)	0.686 (1.00)
MAP7	3 (5%)	59	0.857 (1.00)	0.826 (1.00)			1 (1.00)	0.813 (1.00)	0.498 (1.00)	0.793 (1.00)	0.481 (1.00)	0.765 (1.00)
NOM1	6 (10%)	56	0.639 (1.00)	0.885 (1.00)			0.647 (1.00)	1 (1.00)	1 (1.00)	0.788 (1.00)	1 (1.00)	0.16 (1.00)
SHOX2	3 (5%)	59	0.0435 (1.00)
HSD17B1	4 (6%)	58	0.456 (1.00)	0.479 (1.00)	0.878 (1.00)	0.507 (1.00)	0.905 (1.00)	0.00782 (1)	0.824 (1.00)	0.84 (1.00)	1 (1.00)	0.312 (1.00)
PRKAR1A	6 (10%)	56	0.838 (1.00)	0.471 (1.00)	0.82 (1.00)	0.792 (1.00)	0.228 (1.00)	0.398 (1.00)	0.169 (1.00)	0.587 (1.00)	0.0883 (1.00)	0.18 (1.00)
KRTAP5-5	3 (5%)	59	0.0636 (1.00)
DLEU7	3 (5%)	59	0.715 (1.00)
FEZ2	3 (5%)	59	0.855 (1.00)	0.0402 (1.00)			0.24 (1.00)	0.815 (1.00)	0.279 (1.00)	0.791 (1.00)	0.485 (1.00)	0.497 (1.00)
RASIP1	6 (10%)	56	0.0634 (1.00)	0.181 (1.00)			0.0028 (1)	0.189 (1.00)	0.117 (1.00)	0.698 (1.00)	0.0434 (1.00)	0.739 (1.00)
JMJD4	3 (5%)	59	0.498 (1.00)
COQ2	5 (8%)	57	0.133 (1.00)	0.085 (1.00)			0.442 (1.00)	0.603 (1.00)	1 (1.00)	0.669 (1.00)	0.77 (1.00)	0.491 (1.00)
UQCRFS1	5 (8%)	57	0.623 (1.00)	0.452 (1.00)			1 (1.00)	0.877 (1.00)	0.609 (1.00)	0.203 (1.00)	0.593 (1.00)	0.118 (1.00)
C9ORF66	5 (8%)	57	0.407 (1.00)	1 (1.00)			0.368 (1.00)	0.514 (1.00)	1 (1.00)	0.936 (1.00)	0.923 (1.00)	0.882 (1.00)
POLRMT	4 (6%)	58	0.517 (1.00)	0.084 (1.00)	0.108 (1.00)	0.349 (1.00)	0.369 (1.00)	0.0581 (1.00)	0.183 (1.00)	0.262 (1.00)	0.234 (1.00)	0.55 (1.00)
ADAMTS7	4 (6%)	58	0.0101 (1)	0.722 (1.00)	0.0276 (1.00)	0.351 (1.00)	0.131 (1.00)	0.438 (1.00)	0.101 (1.00)	0.263 (1.00)	0.209 (1.00)	0.349 (1.00)
BTNL9	4 (6%)	58	0.0566 (1.00)	0.18 (1.00)			0.153 (1.00)	0.0965 (1.00)	0.494 (1.00)	1 (1.00)	0.69 (1.00)	1 (1.00)
NF1	7 (11%)	55	0.336 (1.00)	0.828 (1.00)	0.819 (1.00)	0.392 (1.00)	0.314 (1.00)	0.19 (1.00)	0.877 (1.00)	0.883 (1.00)	0.0495 (1.00)	0.417 (1.00)
ZNF814	3 (5%)	59	0.943 (1.00)
RNF135	3 (5%)	59	0.717 (1.00)
CSGALNACT2	3 (5%)	59	0.856 (1.00)	0.221 (1.00)			0.772 (1.00)	0.816 (1.00)	0.279 (1.00)	0.874 (1.00)	0.482 (1.00)	0.942 (1.00)
SPIRE2	3 (5%)	59	0.942 (1.00)	0.131 (1.00)			1 (1.00)	0.812 (1.00)	0.768 (1.00)	0.793 (1.00)	0.544 (1.00)	1 (1.00)
CYP4A22	4 (6%)	58	0.152 (1.00)	0.824 (1.00)			0.224 (1.00)	0.485 (1.00)	0.182 (1.00)	0.199 (1.00)	0.0481 (1.00)	0.879 (1.00)
HLA-A	3 (5%)	59	0.718 (1.00)	0.95 (1.00)			0.866 (1.00)	0.196 (1.00)	0.768 (1.00)	0.51 (1.00)	1 (1.00)	0.347 (1.00)
GLI3	5 (8%)	57	0.126 (1.00)	0.623 (1.00)			0.907 (1.00)	0.876 (1.00)	0.37 (1.00)	0.414 (1.00)	0.512 (1.00)	0.138 (1.00)

'ZFPM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.433 (Fisher's exact test), Q value = 1

Table S1. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
ZFPM1 MUTATED	5	6	1	6	5	1	0
ZFPM1 WILD-TYPE	5	8	6	8	3	3	3

'ZFPM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0988 (Fisher's exact test), Q value = 1

Table S2. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
ZFPM1 MUTATED	5	4	5	2	2	3	0
ZFPM1 WILD-TYPE	7	7	0	8	4	6	2

'ZFPM1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.375 (Fisher's exact test), Q value = 1

Table S3. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
ZFPM1 MUTATED	3	5	2	2
ZFPM1 WILD-TYPE	4	2	4	6

'ZFPM1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.872 (Fisher's exact test), Q value = 1

Table S4. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ZFPM1 MUTATED	2	4	1	1	1	1	1	1
ZFPM1 WILD-TYPE	3	2	4	2	2	0	2	1

'ZFPM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.24 (Fisher's exact test), Q value = 1

Table S5. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
ZFPM1 MUTATED	7	1	7	6
ZFPM1 WILD-TYPE	9	8	6	10

'ZFPM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.747 (Fisher's exact test), Q value = 1

Table S6. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZFPM1 MUTATED	8	6	1	6
ZFPM1 WILD-TYPE	8	10	3	12

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S7. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
ZFPM1 MUTATED	8	8	5
ZFPM1 WILD-TYPE	13	9	12

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.921 (Fisher's exact test), Q value = 1

Table S8. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZFPM1 MUTATED	5	8	2	5	1
ZFPM1 WILD-TYPE	8	10	6	9	1

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.742 (Fisher's exact test), Q value = 1

Table S9. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
ZFPM1 MUTATED	4	5	7	5
ZFPM1 WILD-TYPE	8	7	7	11

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.535 (Fisher's exact test), Q value = 1

Table S10. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
ZFPM1 MUTATED	1	7	5	5	2	1
ZFPM1 WILD-TYPE	5	9	4	5	5	5

'LACTB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0741 (Fisher's exact test), Q value = 1

Table S11. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
LACTB MUTATED	5	3	2	1	5	2	1
LACTB WILD-TYPE	5	11	5	13	3	2	2

'LACTB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.375 (Fisher's exact test), Q value = 1

Table S12. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
LACTB MUTATED	2	5	1	5	2	1	1
LACTB WILD-TYPE	10	6	4	5	4	8	1

'LACTB MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.893 (Fisher's exact test), Q value = 1

Table S13. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
LACTB MUTATED	3	2	1	2
LACTB WILD-TYPE	4	5	5	6

'LACTB MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.57 (Fisher's exact test), Q value = 1

Table S14. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
LACTB MUTATED	2	1	2	0	2	0	0	1
LACTB WILD-TYPE	3	5	3	3	1	1	3	1

'LACTB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S15. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
LACTB MUTATED	5	3	4	5
LACTB WILD-TYPE	11	6	9	11

'LACTB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S16. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
LACTB MUTATED	4	5	3	5
LACTB WILD-TYPE	12	11	1	13

'LACTB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.934 (Fisher's exact test), Q value = 1

Table S17. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
LACTB MUTATED	6	5	6
LACTB WILD-TYPE	15	12	11

'LACTB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.75 (Fisher's exact test), Q value = 1

Table S18. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
LACTB MUTATED	4	5	4	4	0
LACTB WILD-TYPE	9	13	4	10	2

'LACTB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S19. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
LACTB MUTATED	2	5	5	5
LACTB WILD-TYPE	10	7	9	11

'LACTB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S20. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
LACTB MUTATED	2	4	3	1	4	3
LACTB WILD-TYPE	4	12	6	9	3	3

'CCDC102A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.66 (Fisher's exact test), Q value = 1

Table S21. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
CCDC102A MUTATED	2	4	3	2	3	2	1
CCDC102A WILD-TYPE	8	10	4	12	5	2	2

'CCDC102A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.59 (Fisher's exact test), Q value = 1

Table S22. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
CCDC102A MUTATED	2	2	1	3	3	4	1
CCDC102A WILD-TYPE	10	9	4	7	3	5	1

'CCDC102A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S23. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
CCDC102A MUTATED	2	2	1	2
CCDC102A WILD-TYPE	5	5	5	6

'CCDC102A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S24. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CCDC102A MUTATED	1	1	0	1	1	1	1	1
CCDC102A WILD-TYPE	4	5	5	2	2	0	2	1

'CCDC102A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.976 (Fisher's exact test), Q value = 1

Table S25. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
CCDC102A MUTATED	4	3	4	5
CCDC102A WILD-TYPE	12	6	9	11

'CCDC102A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S26. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CCDC102A MUTATED	4	4	1	7
CCDC102A WILD-TYPE	12	12	3	11

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.498 (Fisher's exact test), Q value = 1

Table S27. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
CCDC102A MUTATED	5	4	7
CCDC102A WILD-TYPE	16	13	10

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.469 (Fisher's exact test), Q value = 1

Table S28. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CCDC102A MUTATED	2	6	4	4	0
CCDC102A WILD-TYPE	11	12	4	10	2

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 1

Table S29. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
CCDC102A MUTATED	1	5	4	6
CCDC102A WILD-TYPE	11	7	10	10

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S30. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
CCDC102A MUTATED	0	6	3	3	1	3
CCDC102A WILD-TYPE	6	10	6	7	6	3

'ZNF517 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.945 (Fisher's exact test), Q value = 1

Table S31. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
ZNF517 MUTATED	3	3	2	2	2	1	0
ZNF517 WILD-TYPE	7	11	5	12	6	3	3

'ZNF517 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S32. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
ZNF517 MUTATED	3	1	0	1	2	2	0
ZNF517 WILD-TYPE	9	10	5	9	4	7	2

'ZNF517 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S33. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
ZNF517 MUTATED	4	1	2	2
ZNF517 WILD-TYPE	12	8	11	14

'ZNF517 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.952 (Fisher's exact test), Q value = 1

Table S34. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZNF517 MUTATED	3	2	1	3
ZNF517 WILD-TYPE	13	14	3	15

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.275 (Fisher's exact test), Q value = 1

Table S35. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
ZNF517 MUTATED	2	5	2
ZNF517 WILD-TYPE	19	12	15

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S36. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZNF517 MUTATED	1	3	1	4	0
ZNF517 WILD-TYPE	12	15	7	10	2

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S37. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
ZNF517 MUTATED	3	2	2	2
ZNF517 WILD-TYPE	9	10	12	14

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.461 (Fisher's exact test), Q value = 1

Table S38. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
ZNF517 MUTATED	0	2	1	4	1	1
ZNF517 WILD-TYPE	6	14	8	6	6	5

'MAL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.915 (Fisher's exact test), Q value = 1

Table S39. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
MAL2 MUTATED	1	3	2	3	2	0	0
MAL2 WILD-TYPE	9	11	5	11	6	4	3

'MAL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0795 (Fisher's exact test), Q value = 1

Table S40. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
MAL2 MUTATED	3	0	0	0	2	2	1
MAL2 WILD-TYPE	9	11	5	10	4	7	1

'MAL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 1

Table S41. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
MAL2 MUTATED	2	0	0	2
MAL2 WILD-TYPE	5	7	6	6

'MAL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S42. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
MAL2 MUTATED	1	1	1	1	0	0	0	0
MAL2 WILD-TYPE	4	5	4	2	3	1	3	2

'MAL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S43. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
MAL2 MUTATED	3	2	0	3
MAL2 WILD-TYPE	13	7	13	13

'MAL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S44. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MAL2 MUTATED	4	1	0	3
MAL2 WILD-TYPE	12	15	4	15

'MAL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.707 (Fisher's exact test), Q value = 1

Table S45. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
MAL2 MUTATED	2	3	3
MAL2 WILD-TYPE	19	14	14

'MAL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.267 (Fisher's exact test), Q value = 1

Table S46. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MAL2 MUTATED	0	3	1	4	0
MAL2 WILD-TYPE	13	15	7	10	2

'MAL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S47. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
MAL2 MUTATED	2	2	1	3
MAL2 WILD-TYPE	10	10	13	13

'MAL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.506 (Fisher's exact test), Q value = 1

Table S48. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
MAL2 MUTATED	0	3	0	3	1	1
MAL2 WILD-TYPE	6	13	9	7	6	5

'TOR3A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.19 (Fisher's exact test), Q value = 1

Table S49. Gene #6: 'TOR3A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
TOR3A MUTATED	4	3	0	1	3	0	0
TOR3A WILD-TYPE	6	11	7	13	5	4	3

'TOR3A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.307 (Fisher's exact test), Q value = 1

Table S50. Gene #6: 'TOR3A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
TOR3A MUTATED	0	4	1	2	1	3	0
TOR3A WILD-TYPE	12	7	4	8	5	6	2

'TOR3A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.112 (Fisher's exact test), Q value = 1

Table S51. Gene #6: 'TOR3A MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
TOR3A MUTATED	1	1	3	0
TOR3A WILD-TYPE	6	6	3	8

'TOR3A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.313 (Fisher's exact test), Q value = 1

Table S52. Gene #6: 'TOR3A MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TOR3A MUTATED	0	1	2	0	0	1	1	0
TOR3A WILD-TYPE	5	5	3	3	3	0	2	2

'TOR3A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.556 (Fisher's exact test), Q value = 1

Table S53. Gene #6: 'TOR3A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
TOR3A MUTATED	2	1	4	4
TOR3A WILD-TYPE	14	8	9	12

'TOR3A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00508 (Fisher's exact test), Q value = 1

Table S54. Gene #6: 'TOR3A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TOR3A MUTATED	0	3	3	5
TOR3A WILD-TYPE	16	13	1	13

Figure S1. Get High-res Image Gene #6: 'TOR3A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'TOR3A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S55. Gene #6: 'TOR3A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
TOR3A MUTATED	4	3	4
TOR3A WILD-TYPE	17	14	13

'TOR3A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S56. Gene #6: 'TOR3A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TOR3A MUTATED	2	5	2	2	0
TOR3A WILD-TYPE	11	13	6	12	2

'TOR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S57. Gene #6: 'TOR3A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
TOR3A MUTATED	1	2	4	4
TOR3A WILD-TYPE	11	10	10	12

'TOR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.666 (Fisher's exact test), Q value = 1

Table S58. Gene #6: 'TOR3A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
TOR3A MUTATED	1	4	3	1	2	0
TOR3A WILD-TYPE	5	12	6	9	5	6

'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S59. Gene #7: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
TP53 MUTATED	4	1	2	2	4	0	0
TP53 WILD-TYPE	6	13	5	12	4	4	3

'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.346 (Fisher's exact test), Q value = 1

Table S60. Gene #7: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
TP53 MUTATED	2	3	1	2	1	1	2
TP53 WILD-TYPE	10	8	4	8	5	8	0

'TP53 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.275 (Fisher's exact test), Q value = 1

Table S61. Gene #7: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
TP53 MUTATED	2	2	0	4
TP53 WILD-TYPE	5	5	6	4

'TP53 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S62. Gene #7: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TP53 MUTATED	3	2	0	1	1	0	1	0
TP53 WILD-TYPE	2	4	5	2	2	1	2	2

'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0299 (Fisher's exact test), Q value = 1

Table S63. Gene #7: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
TP53 MUTATED	4	3	5	0
TP53 WILD-TYPE	12	6	8	16

Figure S2. Get High-res Image Gene #7: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.322 (Fisher's exact test), Q value = 1

Table S64. Gene #7: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TP53 MUTATED	4	4	2	2
TP53 WILD-TYPE	12	12	2	16

'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0243 (Fisher's exact test), Q value = 1

Table S65. Gene #7: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
TP53 MUTATED	7	5	0
TP53 WILD-TYPE	14	12	17

Figure S3. Get High-res Image Gene #7: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.596 (Fisher's exact test), Q value = 1

Table S66. Gene #7: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TP53 MUTATED	4	2	2	4	0
TP53 WILD-TYPE	9	16	6	10	2

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0332 (Fisher's exact test), Q value = 1

Table S67. Gene #7: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
TP53 MUTATED	4	3	5	0
TP53 WILD-TYPE	8	9	9	16

Figure S4. Get High-res Image Gene #7: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0834 (Fisher's exact test), Q value = 1

Table S68. Gene #7: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
TP53 MUTATED	2	1	4	2	3	0
TP53 WILD-TYPE	4	15	5	8	4	6

'CLDN23 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.225 (Fisher's exact test), Q value = 1

Table S69. Gene #8: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
CLDN23 MUTATED	1	4	0	3	0	2	0
CLDN23 WILD-TYPE	9	10	7	11	8	2	3

'CLDN23 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S70. Gene #8: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
CLDN23 MUTATED	1	1	1	1	2	3	1
CLDN23 WILD-TYPE	11	10	4	9	4	6	1

'CLDN23 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S71. Gene #8: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
CLDN23 MUTATED	1	1	0	1
CLDN23 WILD-TYPE	6	6	6	7

'CLDN23 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S72. Gene #8: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CLDN23 MUTATED	1	0	0	0	1	0	0	1
CLDN23 WILD-TYPE	4	6	5	3	2	1	3	1

'CLDN23 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0353 (Fisher's exact test), Q value = 1

Table S73. Gene #8: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
CLDN23 MUTATED	1	1	1	7
CLDN23 WILD-TYPE	15	8	12	9

Figure S5. Get High-res Image Gene #8: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'CLDN23 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.212 (Fisher's exact test), Q value = 1

Table S74. Gene #8: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CLDN23 MUTATED	3	1	0	6
CLDN23 WILD-TYPE	13	15	4	12

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.345 (Fisher's exact test), Q value = 1

Table S75. Gene #8: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
CLDN23 MUTATED	2	3	5
CLDN23 WILD-TYPE	19	14	12

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S76. Gene #8: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CLDN23 MUTATED	1	4	3	1	1
CLDN23 WILD-TYPE	12	14	5	13	1

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S77. Gene #8: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
CLDN23 MUTATED	1	2	2	5
CLDN23 WILD-TYPE	11	10	12	11

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.307 (Fisher's exact test), Q value = 1

Table S78. Gene #8: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
CLDN23 MUTATED	0	4	2	0	2	2
CLDN23 WILD-TYPE	6	12	7	10	5	4

'GDF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0265 (Fisher's exact test), Q value = 1

Table S79. Gene #9: 'GDF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
GDF1 MUTATED	0	1	0	0	3	0	1
GDF1 WILD-TYPE	10	13	7	14	5	4	2

Figure S6. Get High-res Image Gene #9: 'GDF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'GDF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.14 (Fisher's exact test), Q value = 1

Table S80. Gene #9: 'GDF1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
GDF1 MUTATED	0	0	0	3	0	1	0
GDF1 WILD-TYPE	12	11	5	7	6	8	2

'GDF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S81. Gene #9: 'GDF1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
GDF1 MUTATED	0	1	2	1
GDF1 WILD-TYPE	16	8	11	15

'GDF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.354 (Fisher's exact test), Q value = 1

Table S82. Gene #9: 'GDF1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
GDF1 MUTATED	0	3	0	1
GDF1 WILD-TYPE	16	13	4	17

'GDF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.238 (Fisher's exact test), Q value = 1

Table S83. Gene #9: 'GDF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
GDF1 MUTATED	0	2	2
GDF1 WILD-TYPE	21	15	15

'GDF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S84. Gene #9: 'GDF1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
GDF1 MUTATED	0	3	0	1	0
GDF1 WILD-TYPE	13	15	8	13	2

'GDF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 1

Table S85. Gene #9: 'GDF1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
GDF1 MUTATED	1	2	0	1
GDF1 WILD-TYPE	11	10	14	15

'GDF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S86. Gene #9: 'GDF1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
GDF1 MUTATED	0	3	0	1	0	0
GDF1 WILD-TYPE	6	13	9	9	7	6

'LZTR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.021 (Fisher's exact test), Q value = 1

Table S87. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
LZTR1 MUTATED	3	0	0	0	2	0	1
LZTR1 WILD-TYPE	7	14	7	14	6	4	2

Figure S7. Get High-res Image Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'LZTR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.943 (Fisher's exact test), Q value = 1

Table S88. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
LZTR1 MUTATED	2	1	0	1	0	0	0
LZTR1 WILD-TYPE	10	10	5	9	6	9	2

'LZTR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 1

Table S89. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
LZTR1 MUTATED	3	1	0	0
LZTR1 WILD-TYPE	13	8	13	16

'LZTR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.117 (Fisher's exact test), Q value = 1

Table S90. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
LZTR1 MUTATED	2	1	1	0
LZTR1 WILD-TYPE	14	15	3	18

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.183 (Fisher's exact test), Q value = 1

Table S91. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
LZTR1 MUTATED	1	3	0
LZTR1 WILD-TYPE	20	14	17

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0147 (Fisher's exact test), Q value = 1

Table S92. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
LZTR1 MUTATED	0	0	0	3	1
LZTR1 WILD-TYPE	13	18	8	11	1

Figure S8. Get High-res Image Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.387 (Fisher's exact test), Q value = 1

Table S93. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
LZTR1 MUTATED	2	1	1	0
LZTR1 WILD-TYPE	10	11	13	16

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0661 (Fisher's exact test), Q value = 1

Table S94. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
LZTR1 MUTATED	0	0	0	2	2	0
LZTR1 WILD-TYPE	6	16	9	8	5	6

'ANKRD43 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S95. Gene #11: 'ANKRD43 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
ANKRD43 MUTATED	1	4	3	4	5	1	1
ANKRD43 WILD-TYPE	9	10	4	10	3	3	2

'ANKRD43 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S96. Gene #11: 'ANKRD43 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
ANKRD43 MUTATED	5	0	2	4	2	2	1
ANKRD43 WILD-TYPE	7	11	3	6	4	7	1

'ANKRD43 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S97. Gene #11: 'ANKRD43 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
ANKRD43 MUTATED	1	2	1	4
ANKRD43 WILD-TYPE	6	5	5	4

'ANKRD43 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.599 (Fisher's exact test), Q value = 1

Table S98. Gene #11: 'ANKRD43 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ANKRD43 MUTATED	2	2	0	1	1	1	1	0
ANKRD43 WILD-TYPE	3	4	5	2	2	0	2	2

'ANKRD43 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.268 (Fisher's exact test), Q value = 1

Table S99. Gene #11: 'ANKRD43 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
ANKRD43 MUTATED	4	4	5	2
ANKRD43 WILD-TYPE	12	5	8	14

'ANKRD43 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.226 (Fisher's exact test), Q value = 1

Table S100. Gene #11: 'ANKRD43 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ANKRD43 MUTATED	5	7	0	3
ANKRD43 WILD-TYPE	11	9	4	15

'ANKRD43 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.565 (Fisher's exact test), Q value = 1

Table S101. Gene #11: 'ANKRD43 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
ANKRD43 MUTATED	7	6	3
ANKRD43 WILD-TYPE	14	11	14

'ANKRD43 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.103 (Fisher's exact test), Q value = 1

Table S102. Gene #11: 'ANKRD43 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ANKRD43 MUTATED	6	4	0	6	0
ANKRD43 WILD-TYPE	7	14	8	8	2

'ANKRD43 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.521 (Fisher's exact test), Q value = 1

Table S103. Gene #11: 'ANKRD43 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
ANKRD43 MUTATED	4	3	6	3
ANKRD43 WILD-TYPE	8	9	8	13

'ANKRD43 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.596 (Fisher's exact test), Q value = 1

Table S104. Gene #11: 'ANKRD43 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
ANKRD43 MUTATED	2	3	3	5	1	2
ANKRD43 WILD-TYPE	4	13	6	5	6	4

'KCNK17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.156 (Fisher's exact test), Q value = 1

Table S105. Gene #12: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
KCNK17 MUTATED	1	1	1	1	4	1	0
KCNK17 WILD-TYPE	9	13	6	13	4	3	3

'KCNK17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0103 (Fisher's exact test), Q value = 1

Table S106. Gene #12: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
KCNK17 MUTATED	0	1	2	4	0	0	1
KCNK17 WILD-TYPE	12	10	3	6	6	9	1

Figure S9. Get High-res Image Gene #12: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'KCNK17 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.376 (Fisher's exact test), Q value = 1

Table S107. Gene #12: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
KCNK17 MUTATED	1	3	0	2
KCNK17 WILD-TYPE	6	4	6	6

'KCNK17 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S108. Gene #12: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
KCNK17 MUTATED	1	3	0	0	1	0	0	1
KCNK17 WILD-TYPE	4	3	5	3	2	1	3	1

'KCNK17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.074 (Fisher's exact test), Q value = 1

Table S109. Gene #12: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
KCNK17 MUTATED	1	1	5	1
KCNK17 WILD-TYPE	15	8	8	15

'KCNK17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00953 (Fisher's exact test), Q value = 1

Table S110. Gene #12: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KCNK17 MUTATED	0	6	1	1
KCNK17 WILD-TYPE	16	10	3	17

Figure S10. Get High-res Image Gene #12: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.797 (Fisher's exact test), Q value = 1

Table S111. Gene #12: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
KCNK17 MUTATED	4	2	2
KCNK17 WILD-TYPE	17	15	15

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S112. Gene #12: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KCNK17 MUTATED	3	1	2	2	0
KCNK17 WILD-TYPE	10	17	6	12	2

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.405 (Fisher's exact test), Q value = 1

Table S113. Gene #12: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
KCNK17 MUTATED	2	1	4	1
KCNK17 WILD-TYPE	10	11	10	15

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.567 (Fisher's exact test), Q value = 1

Table S114. Gene #12: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
KCNK17 MUTATED	1	1	3	1	1	1
KCNK17 WILD-TYPE	5	15	6	9	6	5

'RINL MUTATION STATUS' versus 'CN_CNMF'

P value = 0.326 (Fisher's exact test), Q value = 1

Table S115. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
RINL MUTATED	4	1	0	2	1	0	0
RINL WILD-TYPE	6	13	7	12	7	4	3

'RINL MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S116. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
RINL MUTATED	2	2	1	1	0	1	0
RINL WILD-TYPE	10	9	4	9	6	8	2

'RINL MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0749 (Fisher's exact test), Q value = 1

Table S117. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
RINL MUTATED	3	1	0	0
RINL WILD-TYPE	4	6	6	8

'RINL MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.579 (Fisher's exact test), Q value = 1

Table S118. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
RINL MUTATED	1	0	1	0	1	0	0	1
RINL WILD-TYPE	4	6	4	3	2	1	3	1

'RINL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S119. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
RINL MUTATED	4	1	1	1
RINL WILD-TYPE	12	8	12	15

'RINL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.275 (Fisher's exact test), Q value = 1

Table S120. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RINL MUTATED	4	1	1	1
RINL WILD-TYPE	12	15	3	17

'RINL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.268 (Fisher's exact test), Q value = 1

Table S121. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
RINL MUTATED	1	4	2
RINL WILD-TYPE	20	13	15

'RINL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.169 (Fisher's exact test), Q value = 1

Table S122. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RINL MUTATED	0	3	0	4	0
RINL WILD-TYPE	13	15	8	10	2

'RINL MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.098 (Fisher's exact test), Q value = 1

Table S123. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
RINL MUTATED	3	3	0	1
RINL WILD-TYPE	9	9	14	15

'RINL MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.362 (Fisher's exact test), Q value = 1

Table S124. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
RINL MUTATED	0	3	0	3	1	0
RINL WILD-TYPE	6	13	9	7	6	6

'ZAR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 1

Table S125. Gene #14: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
ZAR1 MUTATED	0	3	0	3	2	2	1
ZAR1 WILD-TYPE	10	11	7	11	6	2	2

'ZAR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.298 (Fisher's exact test), Q value = 1

Table S126. Gene #14: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
ZAR1 MUTATED	3	1	2	0	2	1	0
ZAR1 WILD-TYPE	9	10	3	10	4	8	2

'ZAR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S127. Gene #14: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
ZAR1 MUTATED	2	2	0	0
ZAR1 WILD-TYPE	5	5	6	8

'ZAR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S128. Gene #14: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ZAR1 MUTATED	0	2	1	0	1	0	0	0
ZAR1 WILD-TYPE	5	4	4	3	2	1	3	2

'ZAR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S129. Gene #14: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
ZAR1 MUTATED	3	0	2	4
ZAR1 WILD-TYPE	13	9	11	12

'ZAR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.87 (Fisher's exact test), Q value = 1

Table S130. Gene #14: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZAR1 MUTATED	3	2	0	4
ZAR1 WILD-TYPE	13	14	4	14

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S131. Gene #14: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
ZAR1 MUTATED	4	1	4
ZAR1 WILD-TYPE	17	16	13

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.97 (Fisher's exact test), Q value = 1

Table S132. Gene #14: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZAR1 MUTATED	2	4	1	2	0
ZAR1 WILD-TYPE	11	14	7	12	2

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S133. Gene #14: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
ZAR1 MUTATED	2	0	3	4
ZAR1 WILD-TYPE	10	12	11	12

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.701 (Fisher's exact test), Q value = 1

Table S134. Gene #14: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
ZAR1 MUTATED	0	4	2	2	0	1
ZAR1 WILD-TYPE	6	12	7	8	7	5

'CTNNB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.641 (Fisher's exact test), Q value = 1

Table S135. Gene #15: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
CTNNB1 MUTATED	2	1	0	3	1	0	1
CTNNB1 WILD-TYPE	8	13	7	11	7	4	2

'CTNNB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.32 (Fisher's exact test), Q value = 1

Table S136. Gene #15: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
CTNNB1 MUTATED	3	2	0	1	0	0	1
CTNNB1 WILD-TYPE	9	9	5	9	6	9	1

'CTNNB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.112 (Fisher's exact test), Q value = 1

Table S137. Gene #15: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
CTNNB1 MUTATED	3	0	0	2
CTNNB1 WILD-TYPE	4	7	6	6

'CTNNB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.313 (Fisher's exact test), Q value = 1

Table S138. Gene #15: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CTNNB1 MUTATED	2	1	0	0	2	0	0	0
CTNNB1 WILD-TYPE	3	5	5	3	1	1	3	2

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00852 (Fisher's exact test), Q value = 1

Table S139. Gene #15: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
CTNNB1 MUTATED	4	3	0	0
CTNNB1 WILD-TYPE	12	6	13	16

Figure S11. Get High-res Image Gene #15: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00605 (Fisher's exact test), Q value = 1

Table S140. Gene #15: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CTNNB1 MUTATED	6	1	0	0
CTNNB1 WILD-TYPE	10	15	4	18

Figure S12. Get High-res Image Gene #15: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00525 (Fisher's exact test), Q value = 1

Table S141. Gene #15: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
CTNNB1 MUTATED	1	6	0
CTNNB1 WILD-TYPE	20	11	17

Figure S13. Get High-res Image Gene #15: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.167 (Fisher's exact test), Q value = 1

Table S142. Gene #15: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CTNNB1 MUTATED	0	3	0	4	0
CTNNB1 WILD-TYPE	13	15	8	10	2

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0429 (Fisher's exact test), Q value = 1

Table S143. Gene #15: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
CTNNB1 MUTATED	2	4	1	0
CTNNB1 WILD-TYPE	10	8	13	16

Figure S14. Get High-res Image Gene #15: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S144. Gene #15: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
CTNNB1 MUTATED	0	3	0	2	2	0
CTNNB1 WILD-TYPE	6	13	9	8	5	6

'APOE MUTATION STATUS' versus 'CN_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 1

Table S145. Gene #16: 'APOE MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
APOE MUTATED	1	1	2	0	3	0	0
APOE WILD-TYPE	9	13	5	14	5	4	3

'APOE MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.707 (Fisher's exact test), Q value = 1

Table S146. Gene #16: 'APOE MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
APOE MUTATED	1	1	0	3	0	1	0
APOE WILD-TYPE	11	10	5	7	6	8	2

'APOE MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S147. Gene #16: 'APOE MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
APOE MUTATED	0	2	0	1
APOE WILD-TYPE	7	5	6	7

'APOE MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.383 (Fisher's exact test), Q value = 1

Table S148. Gene #16: 'APOE MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
APOE MUTATED	0	1	0	0	0	0	1	1
APOE WILD-TYPE	5	5	5	3	3	1	2	1

'APOE MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0376 (Fisher's exact test), Q value = 1

Table S149. Gene #16: 'APOE MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
APOE MUTATED	2	0	4	0
APOE WILD-TYPE	14	9	9	16

Figure S15. Get High-res Image Gene #16: 'APOE MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'APOE MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S150. Gene #16: 'APOE MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
APOE MUTATED	1	3	1	1
APOE WILD-TYPE	15	13	3	17

'APOE MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S151. Gene #16: 'APOE MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
APOE MUTATED	2	3	1
APOE WILD-TYPE	19	14	16

'APOE MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S152. Gene #16: 'APOE MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
APOE MUTATED	1	3	0	2	0
APOE WILD-TYPE	12	15	8	12	2

'APOE MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.171 (Fisher's exact test), Q value = 1

Table S153. Gene #16: 'APOE MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
APOE MUTATED	1	3	2	0
APOE WILD-TYPE	11	9	12	16

'APOE MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.921 (Fisher's exact test), Q value = 1

Table S154. Gene #16: 'APOE MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
APOE MUTATED	0	2	1	2	1	0
APOE WILD-TYPE	6	14	8	8	6	6

'GPRIN2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S155. Gene #17: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
GPRIN2 MUTATED	0	2	2	2	1	0	1
GPRIN2 WILD-TYPE	10	12	5	12	7	4	2

'GPRIN2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.178 (Fisher's exact test), Q value = 1

Table S156. Gene #17: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
GPRIN2 MUTATED	1	0	0	4	1	1	0
GPRIN2 WILD-TYPE	11	11	5	6	5	8	2

'GPRIN2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.227 (Fisher's exact test), Q value = 1

Table S157. Gene #17: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
GPRIN2 MUTATED	2	2	0	0
GPRIN2 WILD-TYPE	5	5	6	8

'GPRIN2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.692 (Fisher's exact test), Q value = 1

Table S158. Gene #17: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
GPRIN2 MUTATED	0	1	1	0	1	0	0	1
GPRIN2 WILD-TYPE	5	5	4	3	2	1	3	1

'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.745 (Fisher's exact test), Q value = 1

Table S159. Gene #17: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
GPRIN2 MUTATED	1	2	2	2
GPRIN2 WILD-TYPE	15	7	11	14

'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S160. Gene #17: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
GPRIN2 MUTATED	1	4	0	2
GPRIN2 WILD-TYPE	15	12	4	16

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S161. Gene #17: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
GPRIN2 MUTATED	2	2	3
GPRIN2 WILD-TYPE	19	15	14

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.753 (Fisher's exact test), Q value = 1

Table S162. Gene #17: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
GPRIN2 MUTATED	1	4	1	1	0
GPRIN2 WILD-TYPE	12	14	7	13	2

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.627 (Fisher's exact test), Q value = 1

Table S163. Gene #17: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
GPRIN2 MUTATED	1	3	1	2
GPRIN2 WILD-TYPE	11	9	13	14

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.502 (Fisher's exact test), Q value = 1

Table S164. Gene #17: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
GPRIN2 MUTATED	1	4	0	1	0	1
GPRIN2 WILD-TYPE	5	12	9	9	7	5

'ASPDH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.282 (Fisher's exact test), Q value = 1

Table S165. Gene #18: 'ASPDH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
ASPDH MUTATED	0	2	0	3	3	0	0
ASPDH WILD-TYPE	10	12	7	11	5	4	3

'ASPDH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 1

Table S166. Gene #18: 'ASPDH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
ASPDH MUTATED	3	0	2	2	0	1	0
ASPDH WILD-TYPE	9	11	3	8	6	8	2

'ASPDH MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S167. Gene #18: 'ASPDH MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
ASPDH MUTATED	1	2	0	2
ASPDH WILD-TYPE	6	5	6	6

'ASPDH MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S168. Gene #18: 'ASPDH MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ASPDH MUTATED	0	3	0	1	0	0	1	0
ASPDH WILD-TYPE	5	3	5	2	3	1	2	2

'ASPDH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00903 (Fisher's exact test), Q value = 1

Table S169. Gene #18: 'ASPDH MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
ASPDH MUTATED	3	0	5	0
ASPDH WILD-TYPE	13	9	8	16

Figure S16. Get High-res Image Gene #18: 'ASPDH MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'ASPDH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.398 (Fisher's exact test), Q value = 1

Table S170. Gene #18: 'ASPDH MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ASPDH MUTATED	3	4	0	1
ASPDH WILD-TYPE	13	12	4	17

'ASPDH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S171. Gene #18: 'ASPDH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
ASPDH MUTATED	5	2	1
ASPDH WILD-TYPE	16	15	16

'ASPDH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0324 (Fisher's exact test), Q value = 1

Table S172. Gene #18: 'ASPDH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ASPDH MUTATED	4	0	0	4	0
ASPDH WILD-TYPE	9	18	8	10	2

Figure S17. Get High-res Image Gene #18: 'ASPDH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'ASPDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0702 (Fisher's exact test), Q value = 1

Table S173. Gene #18: 'ASPDH MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
ASPDH MUTATED	4	0	3	1
ASPDH WILD-TYPE	8	12	11	15

'ASPDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0148 (Fisher's exact test), Q value = 1

Table S174. Gene #18: 'ASPDH MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
ASPDH MUTATED	0	0	3	4	0	1
ASPDH WILD-TYPE	6	16	6	6	7	5

Figure S18. Get High-res Image Gene #18: 'ASPDH MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ERCC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.214 (Fisher's exact test), Q value = 1

Table S175. Gene #19: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
ERCC2 MUTATED	0	3	0	5	2	0	0
ERCC2 WILD-TYPE	10	11	7	9	6	4	3

'ERCC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.117 (Fisher's exact test), Q value = 1

Table S176. Gene #19: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
ERCC2 MUTATED	4	0	2	2	0	1	1
ERCC2 WILD-TYPE	8	11	3	8	6	8	1

'ERCC2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0954 (Fisher's exact test), Q value = 1

Table S177. Gene #19: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
ERCC2 MUTATED	0	4	1	3
ERCC2 WILD-TYPE	7	3	5	5

'ERCC2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.233 (Fisher's exact test), Q value = 1

Table S178. Gene #19: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ERCC2 MUTATED	2	3	0	1	0	1	0	1
ERCC2 WILD-TYPE	3	3	5	2	3	0	3	1

'ERCC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S179. Gene #19: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
ERCC2 MUTATED	4	2	3	1
ERCC2 WILD-TYPE	12	7	10	15

'ERCC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S180. Gene #19: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ERCC2 MUTATED	5	4	0	1
ERCC2 WILD-TYPE	11	12	4	17

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S181. Gene #19: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
ERCC2 MUTATED	6	2	2
ERCC2 WILD-TYPE	15	15	15

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.268 (Fisher's exact test), Q value = 1

Table S182. Gene #19: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ERCC2 MUTATED	3	2	0	5	0
ERCC2 WILD-TYPE	10	16	8	9	2

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S183. Gene #19: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
ERCC2 MUTATED	3	2	4	1
ERCC2 WILD-TYPE	9	10	10	15

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S184. Gene #19: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
ERCC2 MUTATED	1	2	2	4	1	0
ERCC2 WILD-TYPE	5	14	7	6	6	6

'IDUA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0199 (Fisher's exact test), Q value = 1

Table S185. Gene #20: 'IDUA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
IDUA MUTATED	1	0	0	2	3	0	2
IDUA WILD-TYPE	9	14	7	12	5	4	1

Figure S19. Get High-res Image Gene #20: 'IDUA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'IDUA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S186. Gene #20: 'IDUA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
IDUA MUTATED	2	2	0	3	0	0	0
IDUA WILD-TYPE	10	9	5	7	6	9	2

'IDUA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.818 (Fisher's exact test), Q value = 1

Table S187. Gene #20: 'IDUA MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
IDUA MUTATED	2	1	0	1
IDUA WILD-TYPE	5	6	6	7

'IDUA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S188. Gene #20: 'IDUA MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
IDUA MUTATED	1	0	1	1	1	0	0	0
IDUA WILD-TYPE	4	6	4	2	2	1	3	2

'IDUA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.571 (Fisher's exact test), Q value = 1

Table S189. Gene #20: 'IDUA MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
IDUA MUTATED	3	2	1	1
IDUA WILD-TYPE	13	7	12	15

'IDUA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S190. Gene #20: 'IDUA MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
IDUA MUTATED	3	3	0	1
IDUA WILD-TYPE	13	13	4	17

'IDUA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S191. Gene #20: 'IDUA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
IDUA MUTATED	3	3	1
IDUA WILD-TYPE	18	14	16

'IDUA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S192. Gene #20: 'IDUA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
IDUA MUTATED	1	2	0	4	0
IDUA WILD-TYPE	12	16	8	10	2

'IDUA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S193. Gene #20: 'IDUA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
IDUA MUTATED	2	2	2	1
IDUA WILD-TYPE	10	10	12	15

'IDUA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S194. Gene #20: 'IDUA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
IDUA MUTATED	1	2	0	3	1	0
IDUA WILD-TYPE	5	14	9	7	6	6

'C1ORF106 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.406 (Fisher's exact test), Q value = 1

Table S195. Gene #21: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
C1ORF106 MUTATED	1	1	0	4	2	0	1
C1ORF106 WILD-TYPE	9	13	7	10	6	4	2

'C1ORF106 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.497 (Fisher's exact test), Q value = 1

Table S196. Gene #21: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
C1ORF106 MUTATED	3	1	0	2	2	0	0
C1ORF106 WILD-TYPE	9	10	5	8	4	9	2

'C1ORF106 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.265 (Fisher's exact test), Q value = 1

Table S197. Gene #21: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
C1ORF106 MUTATED	3	1	0	1
C1ORF106 WILD-TYPE	4	6	6	7

'C1ORF106 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0481 (Fisher's exact test), Q value = 1

Table S198. Gene #21: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
C1ORF106 MUTATED	1	0	0	2	2	0	0	0
C1ORF106 WILD-TYPE	4	6	5	1	1	1	3	2

Figure S20. Get High-res Image Gene #21: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

'C1ORF106 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.412 (Fisher's exact test), Q value = 1

Table S199. Gene #21: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
C1ORF106 MUTATED	4	2	1	1
C1ORF106 WILD-TYPE	12	7	12	15

'C1ORF106 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S200. Gene #21: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
C1ORF106 MUTATED	3	2	1	2
C1ORF106 WILD-TYPE	13	14	3	16

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.627 (Fisher's exact test), Q value = 1

Table S201. Gene #21: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
C1ORF106 MUTATED	4	3	1
C1ORF106 WILD-TYPE	17	14	16

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.691 (Fisher's exact test), Q value = 1

Table S202. Gene #21: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
C1ORF106 MUTATED	1	2	2	3	0
C1ORF106 WILD-TYPE	12	16	6	11	2

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.599 (Fisher's exact test), Q value = 1

Table S203. Gene #21: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
C1ORF106 MUTATED	3	2	2	1
C1ORF106 WILD-TYPE	9	10	12	15

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.988 (Fisher's exact test), Q value = 1

Table S204. Gene #21: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
C1ORF106 MUTATED	1	2	1	2	1	1
C1ORF106 WILD-TYPE	5	14	8	8	6	5

'C10ORF95 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.237 (Fisher's exact test), Q value = 1

Table S205. Gene #22: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
C10ORF95 MUTATED	1	0	0	1	1	1	1
C10ORF95 WILD-TYPE	9	14	7	13	7	3	2

'C10ORF95 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.691 (Fisher's exact test), Q value = 1

Table S206. Gene #22: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
C10ORF95 MUTATED	1	0	0	2	1	1	0
C10ORF95 WILD-TYPE	11	11	5	8	5	8	2

'C10ORF95 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S207. Gene #22: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
C10ORF95 MUTATED	1	2	1	1
C10ORF95 WILD-TYPE	15	7	12	15

'C10ORF95 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S208. Gene #22: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
C10ORF95 MUTATED	1	2	0	2
C10ORF95 WILD-TYPE	15	14	4	16

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S209. Gene #22: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
C10ORF95 MUTATED	3	1	1
C10ORF95 WILD-TYPE	18	16	16

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.359 (Fisher's exact test), Q value = 1

Table S210. Gene #22: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
C10ORF95 MUTATED	1	1	1	1	1
C10ORF95 WILD-TYPE	12	17	7	13	1

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S211. Gene #22: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
C10ORF95 MUTATED	0	1	2	1
C10ORF95 WILD-TYPE	12	11	12	15

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.783 (Fisher's exact test), Q value = 1

Table S212. Gene #22: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
C10ORF95 MUTATED	1	1	0	1	1	0
C10ORF95 WILD-TYPE	5	15	9	9	6	6

'RGS9BP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.202 (Fisher's exact test), Q value = 1

Table S213. Gene #23: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
RGS9BP MUTATED	0	2	3	1	2	0	0
RGS9BP WILD-TYPE	10	12	4	13	6	4	3

'RGS9BP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.578 (Fisher's exact test), Q value = 1

Table S214. Gene #23: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
RGS9BP MUTATED	3	0	0	2	1	2	0
RGS9BP WILD-TYPE	9	11	5	8	5	7	2

'RGS9BP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S215. Gene #23: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
RGS9BP MUTATED	0	1	1	1
RGS9BP WILD-TYPE	7	6	5	7

'RGS9BP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S216. Gene #23: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
RGS9BP MUTATED	0	2	0	0	0	1	0	0
RGS9BP WILD-TYPE	5	4	5	3	3	0	3	2

'RGS9BP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S217. Gene #23: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
RGS9BP MUTATED	2	1	2	2
RGS9BP WILD-TYPE	14	8	11	14

'RGS9BP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S218. Gene #23: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RGS9BP MUTATED	2	3	0	2
RGS9BP WILD-TYPE	14	13	4	16

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 1

Table S219. Gene #23: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
RGS9BP MUTATED	1	4	3
RGS9BP WILD-TYPE	20	13	14

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.963 (Fisher's exact test), Q value = 1

Table S220. Gene #23: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RGS9BP MUTATED	2	2	1	3	0
RGS9BP WILD-TYPE	11	16	7	11	2

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.561 (Fisher's exact test), Q value = 1

Table S221. Gene #23: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
RGS9BP MUTATED	3	1	1	3
RGS9BP WILD-TYPE	9	11	13	13

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.254 (Fisher's exact test), Q value = 1

Table S222. Gene #23: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
RGS9BP MUTATED	1	2	0	3	0	2
RGS9BP WILD-TYPE	5	14	9	7	7	4

'THEM4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 1

Table S223. Gene #24: 'THEM4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
THEM4 MUTATED	1	0	0	1	3	0	0
THEM4 WILD-TYPE	9	14	7	13	5	4	3

'THEM4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.214 (Fisher's exact test), Q value = 1

Table S224. Gene #24: 'THEM4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
THEM4 MUTATED	1	0	0	1	1	0	1
THEM4 WILD-TYPE	11	11	5	9	5	9	1

'THEM4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S225. Gene #24: 'THEM4 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
THEM4 MUTATED	1	1	2	0
THEM4 WILD-TYPE	15	8	11	16

'THEM4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S226. Gene #24: 'THEM4 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
THEM4 MUTATED	2	1	0	1
THEM4 WILD-TYPE	14	15	4	17

'THEM4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.539 (Fisher's exact test), Q value = 1

Table S227. Gene #24: 'THEM4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
THEM4 MUTATED	2	2	0
THEM4 WILD-TYPE	19	15	17

'THEM4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.107 (Fisher's exact test), Q value = 1

Table S228. Gene #24: 'THEM4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
THEM4 MUTATED	0	0	1	3	0
THEM4 WILD-TYPE	13	18	7	11	2

'THEM4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.513 (Fisher's exact test), Q value = 1

Table S229. Gene #24: 'THEM4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
THEM4 MUTATED	1	1	2	0
THEM4 WILD-TYPE	11	11	12	16

'THEM4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.304 (Fisher's exact test), Q value = 1

Table S230. Gene #24: 'THEM4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
THEM4 MUTATED	0	0	1	2	1	0
THEM4 WILD-TYPE	6	16	8	8	6	6

'TSC22D2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.66 (Fisher's exact test), Q value = 1

Table S231. Gene #25: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
TSC22D2 MUTATED	1	1	0	3	2	1	0
TSC22D2 WILD-TYPE	9	13	7	11	6	3	3

'TSC22D2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.265 (Fisher's exact test), Q value = 1

Table S232. Gene #25: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
TSC22D2 MUTATED	1	1	2	1	2	0	0
TSC22D2 WILD-TYPE	11	10	3	9	4	9	2

'TSC22D2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.674 (Fisher's exact test), Q value = 1

Table S233. Gene #25: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
TSC22D2 MUTATED	1	1	1	0
TSC22D2 WILD-TYPE	6	6	5	8

'TSC22D2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.955 (Fisher's exact test), Q value = 1

Table S234. Gene #25: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TSC22D2 MUTATED	0	1	1	0	1	0	0	0
TSC22D2 WILD-TYPE	5	5	4	3	2	1	3	2

'TSC22D2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S235. Gene #25: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
TSC22D2 MUTATED	3	0	2	2
TSC22D2 WILD-TYPE	13	9	11	14

'TSC22D2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S236. Gene #25: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TSC22D2 MUTATED	2	2	1	2
TSC22D2 WILD-TYPE	14	14	3	16

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S237. Gene #25: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
TSC22D2 MUTATED	2	3	2
TSC22D2 WILD-TYPE	19	14	15

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S238. Gene #25: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TSC22D2 MUTATED	1	2	0	4	0
TSC22D2 WILD-TYPE	12	16	8	10	2

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S239. Gene #25: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
TSC22D2 MUTATED	3	1	1	2
TSC22D2 WILD-TYPE	9	11	13	14

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S240. Gene #25: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
TSC22D2 MUTATED	0	2	1	3	1	0
TSC22D2 WILD-TYPE	6	14	8	7	6	6

'SYT8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S241. Gene #26: 'SYT8 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
SYT8 MUTATED	0	2	3	1	1	0	1
SYT8 WILD-TYPE	10	12	4	13	7	4	2

'SYT8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 1

Table S242. Gene #26: 'SYT8 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
SYT8 MUTATED	0	1	0	2	1	1	1
SYT8 WILD-TYPE	12	10	5	8	5	8	1

'SYT8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S243. Gene #26: 'SYT8 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
SYT8 MUTATED	0	0	1	2
SYT8 WILD-TYPE	7	7	5	6

'SYT8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S244. Gene #26: 'SYT8 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
SYT8 MUTATED	1	1	1	0	0	0	0	0
SYT8 WILD-TYPE	4	5	4	3	3	1	3	2

'SYT8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0644 (Fisher's exact test), Q value = 1

Table S245. Gene #26: 'SYT8 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
SYT8 MUTATED	0	3	1	2
SYT8 WILD-TYPE	16	6	12	14

'SYT8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.175 (Fisher's exact test), Q value = 1

Table S246. Gene #26: 'SYT8 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SYT8 MUTATED	0	4	0	2
SYT8 WILD-TYPE	16	12	4	16

'SYT8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S247. Gene #26: 'SYT8 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
SYT8 MUTATED	2	2	2
SYT8 WILD-TYPE	19	15	15

'SYT8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.184 (Fisher's exact test), Q value = 1

Table S248. Gene #26: 'SYT8 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SYT8 MUTATED	1	3	1	0	1
SYT8 WILD-TYPE	12	15	7	14	1

'SYT8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.633 (Fisher's exact test), Q value = 1

Table S249. Gene #26: 'SYT8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
SYT8 MUTATED	0	2	2	2
SYT8 WILD-TYPE	12	10	12	14

'SYT8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.705 (Fisher's exact test), Q value = 1

Table S250. Gene #26: 'SYT8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
SYT8 MUTATED	1	3	1	0	1	0
SYT8 WILD-TYPE	5	13	8	10	6	6

'PLIN5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.896 (Fisher's exact test), Q value = 1

Table S251. Gene #27: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
PLIN5 MUTATED	0	2	1	1	1	0	0
PLIN5 WILD-TYPE	10	12	6	13	7	4	3

'PLIN5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.753 (Fisher's exact test), Q value = 1

Table S252. Gene #27: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
PLIN5 MUTATED	1	0	1	1	1	1	0
PLIN5 WILD-TYPE	11	11	4	9	5	8	2

'PLIN5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.309 (Fisher's exact test), Q value = 1

Table S253. Gene #27: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
PLIN5 MUTATED	1	2	0	0
PLIN5 WILD-TYPE	6	5	6	8

'PLIN5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.382 (Fisher's exact test), Q value = 1

Table S254. Gene #27: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
PLIN5 MUTATED	0	1	0	0	1	0	0	1
PLIN5 WILD-TYPE	5	5	5	3	2	1	3	1

'PLIN5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.797 (Fisher's exact test), Q value = 1

Table S255. Gene #27: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
PLIN5 MUTATED	1	1	2	1
PLIN5 WILD-TYPE	15	8	11	15

'PLIN5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S256. Gene #27: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PLIN5 MUTATED	1	3	0	1
PLIN5 WILD-TYPE	15	13	4	17

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.721 (Fisher's exact test), Q value = 1

Table S257. Gene #27: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
PLIN5 MUTATED	1	2	2
PLIN5 WILD-TYPE	20	15	15

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.266 (Fisher's exact test), Q value = 1

Table S258. Gene #27: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PLIN5 MUTATED	1	4	0	0	0
PLIN5 WILD-TYPE	12	14	8	14	2

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.857 (Fisher's exact test), Q value = 1

Table S259. Gene #27: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
PLIN5 MUTATED	1	2	1	1
PLIN5 WILD-TYPE	11	10	13	15

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.312 (Fisher's exact test), Q value = 1

Table S260. Gene #27: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
PLIN5 MUTATED	0	4	1	0	0	0
PLIN5 WILD-TYPE	6	12	8	10	7	6

'LRIG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S261. Gene #28: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
LRIG1 MUTATED	1	2	3	5	2	2	1
LRIG1 WILD-TYPE	9	12	4	9	6	2	2

'LRIG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.649 (Fisher's exact test), Q value = 1

Table S262. Gene #28: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
LRIG1 MUTATED	3	1	0	2	2	2	1
LRIG1 WILD-TYPE	9	10	5	8	4	7	1

'LRIG1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.283 (Fisher's exact test), Q value = 1

Table S263. Gene #28: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
LRIG1 MUTATED	2	0	0	2
LRIG1 WILD-TYPE	5	7	6	6

'LRIG1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S264. Gene #28: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
LRIG1 MUTATED	1	1	1	1	0	0	0	0
LRIG1 WILD-TYPE	4	5	4	2	3	1	3	2

'LRIG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.871 (Fisher's exact test), Q value = 1

Table S265. Gene #28: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
LRIG1 MUTATED	2	2	3	3
LRIG1 WILD-TYPE	14	7	10	13

'LRIG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.611 (Fisher's exact test), Q value = 1

Table S266. Gene #28: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
LRIG1 MUTATED	3	2	0	5
LRIG1 WILD-TYPE	13	14	4	13

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S267. Gene #28: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
LRIG1 MUTATED	3	5	3
LRIG1 WILD-TYPE	18	12	14

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S268. Gene #28: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
LRIG1 MUTATED	1	3	3	4	0
LRIG1 WILD-TYPE	12	15	5	10	2

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S269. Gene #28: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
LRIG1 MUTATED	4	2	2	3
LRIG1 WILD-TYPE	8	10	12	13

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.985 (Fisher's exact test), Q value = 1

Table S270. Gene #28: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
LRIG1 MUTATED	1	3	2	3	1	1
LRIG1 WILD-TYPE	5	13	7	7	6	5

'HHIPL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.151 (Fisher's exact test), Q value = 1

Table S271. Gene #29: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
HHIPL1 MUTATED	3	0	0	1	2	0	0
HHIPL1 WILD-TYPE	7	14	7	13	6	4	3

'HHIPL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.576 (Fisher's exact test), Q value = 1

Table S272. Gene #29: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
HHIPL1 MUTATED	2	2	0	0	1	0	0
HHIPL1 WILD-TYPE	10	9	5	10	5	9	2

'HHIPL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.566 (Fisher's exact test), Q value = 1

Table S273. Gene #29: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
HHIPL1 MUTATED	3	0	1	1
HHIPL1 WILD-TYPE	13	9	12	15

'HHIPL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S274. Gene #29: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
HHIPL1 MUTATED	2	1	1	1
HHIPL1 WILD-TYPE	14	15	3	17

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 1

Table S275. Gene #29: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
HHIPL1 MUTATED	3	2	0
HHIPL1 WILD-TYPE	18	15	17

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.425 (Fisher's exact test), Q value = 1

Table S276. Gene #29: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
HHIPL1 MUTATED	2	0	1	2	0
HHIPL1 WILD-TYPE	11	18	7	12	2

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0508 (Fisher's exact test), Q value = 1

Table S277. Gene #29: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
HHIPL1 MUTATED	3	0	2	0
HHIPL1 WILD-TYPE	9	12	12	16

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.298 (Fisher's exact test), Q value = 1

Table S278. Gene #29: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
HHIPL1 MUTATED	1	0	2	1	1	0
HHIPL1 WILD-TYPE	5	16	7	9	6	6

'CCDC105 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S279. Gene #30: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
CCDC105 MUTATED	1	2	0	1	2	0	0
CCDC105 WILD-TYPE	9	12	7	13	6	4	3

'CCDC105 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0763 (Fisher's exact test), Q value = 1

Table S280. Gene #30: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
CCDC105 MUTATED	1	1	2	0	1	0	1
CCDC105 WILD-TYPE	11	10	3	10	5	9	1

'CCDC105 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S281. Gene #30: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
CCDC105 MUTATED	0	2	0	1
CCDC105 WILD-TYPE	7	5	6	7

'CCDC105 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S282. Gene #30: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CCDC105 MUTATED	1	1	0	0	0	0	0	1
CCDC105 WILD-TYPE	4	5	5	3	3	1	3	1

'CCDC105 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.933 (Fisher's exact test), Q value = 1

Table S283. Gene #30: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
CCDC105 MUTATED	1	1	2	2
CCDC105 WILD-TYPE	15	8	11	14

'CCDC105 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S284. Gene #30: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CCDC105 MUTATED	3	1	0	2
CCDC105 WILD-TYPE	13	15	4	16

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S285. Gene #30: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
CCDC105 MUTATED	3	2	1
CCDC105 WILD-TYPE	18	15	16

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0546 (Fisher's exact test), Q value = 1

Table S286. Gene #30: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CCDC105 MUTATED	1	0	2	2	1
CCDC105 WILD-TYPE	12	18	6	12	1

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.333 (Fisher's exact test), Q value = 1

Table S287. Gene #30: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
CCDC105 MUTATED	0	2	3	1
CCDC105 WILD-TYPE	12	10	11	15

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.153 (Fisher's exact test), Q value = 1

Table S288. Gene #30: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
CCDC105 MUTATED	0	0	2	1	2	1
CCDC105 WILD-TYPE	6	16	7	9	5	5

'C19ORF10 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.76 (Fisher's exact test), Q value = 1

Table S289. Gene #31: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
C19ORF10 MUTATED	1	1	0	2	1	0	1
C19ORF10 WILD-TYPE	9	13	7	12	7	4	2

'C19ORF10 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.231 (Fisher's exact test), Q value = 1

Table S290. Gene #31: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
C19ORF10 MUTATED	2	0	1	3	0	0	0
C19ORF10 WILD-TYPE	10	11	4	7	6	9	2

'C19ORF10 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S291. Gene #31: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
C19ORF10 MUTATED	1	2	0	1
C19ORF10 WILD-TYPE	6	5	6	7

'C19ORF10 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.392 (Fisher's exact test), Q value = 1

Table S292. Gene #31: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
C19ORF10 MUTATED	0	2	0	0	1	0	0	1
C19ORF10 WILD-TYPE	5	4	5	3	2	1	3	1

'C19ORF10 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.29 (Fisher's exact test), Q value = 1

Table S293. Gene #31: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
C19ORF10 MUTATED	2	2	2	0
C19ORF10 WILD-TYPE	14	7	11	16

'C19ORF10 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S294. Gene #31: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
C19ORF10 MUTATED	2	4	0	0
C19ORF10 WILD-TYPE	14	12	4	18

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.656 (Fisher's exact test), Q value = 1

Table S295. Gene #31: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
C19ORF10 MUTATED	2	3	1
C19ORF10 WILD-TYPE	19	14	16

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S296. Gene #31: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
C19ORF10 MUTATED	2	2	0	2	0
C19ORF10 WILD-TYPE	11	16	8	12	2

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S297. Gene #31: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
C19ORF10 MUTATED	2	2	2	0
C19ORF10 WILD-TYPE	10	10	12	16

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S298. Gene #31: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
C19ORF10 MUTATED	1	2	1	2	0	0
C19ORF10 WILD-TYPE	5	14	8	8	7	6

'OPRD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.907 (Fisher's exact test), Q value = 1

Table S299. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
OPRD1 MUTATED	2	2	2	3	2	0	1
OPRD1 WILD-TYPE	8	12	5	11	6	4	2

'OPRD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.582 (Fisher's exact test), Q value = 1

Table S300. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
OPRD1 MUTATED	3	1	1	2	3	1	0
OPRD1 WILD-TYPE	9	10	4	8	3	8	2

'OPRD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S301. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
OPRD1 MUTATED	2	3	1	0
OPRD1 WILD-TYPE	5	4	5	8

'OPRD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S302. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
OPRD1 MUTATED	0	2	1	1	2	0	0	0
OPRD1 WILD-TYPE	5	4	4	2	1	1	3	2

'OPRD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.826 (Fisher's exact test), Q value = 1

Table S303. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
OPRD1 MUTATED	4	2	3	2
OPRD1 WILD-TYPE	12	7	10	14

'OPRD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S304. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
OPRD1 MUTATED	3	4	1	3
OPRD1 WILD-TYPE	13	12	3	15

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.494 (Fisher's exact test), Q value = 1

Table S305. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
OPRD1 MUTATED	4	5	2
OPRD1 WILD-TYPE	17	12	15

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.615 (Fisher's exact test), Q value = 1

Table S306. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
OPRD1 MUTATED	1	5	1	4	0
OPRD1 WILD-TYPE	12	13	7	10	2

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S307. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
OPRD1 MUTATED	4	3	2	2
OPRD1 WILD-TYPE	8	9	12	14

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.525 (Fisher's exact test), Q value = 1

Table S308. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
OPRD1 MUTATED	0	5	2	3	1	0
OPRD1 WILD-TYPE	6	11	7	7	6	6

'ATXN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.45 (Fisher's exact test), Q value = 1

Table S309. Gene #33: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
ATXN1 MUTATED	2	2	3	3	0	0	0
ATXN1 WILD-TYPE	8	12	4	11	8	4	3

'ATXN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0295 (Fisher's exact test), Q value = 1

Table S310. Gene #33: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
ATXN1 MUTATED	0	1	1	2	2	1	2
ATXN1 WILD-TYPE	12	10	4	8	4	8	0

Figure S21. Get High-res Image Gene #33: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'ATXN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.148 (Fisher's exact test), Q value = 1

Table S311. Gene #33: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
ATXN1 MUTATED	0	0	1	3
ATXN1 WILD-TYPE	7	7	5	5

'ATXN1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.916 (Fisher's exact test), Q value = 1

Table S312. Gene #33: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ATXN1 MUTATED	2	1	1	0	0	0	0	0
ATXN1 WILD-TYPE	3	5	4	3	3	1	3	2

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.14 (Fisher's exact test), Q value = 1

Table S313. Gene #33: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
ATXN1 MUTATED	2	4	2	1
ATXN1 WILD-TYPE	14	5	11	15

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.656 (Fisher's exact test), Q value = 1

Table S314. Gene #33: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ATXN1 MUTATED	3	4	0	2
ATXN1 WILD-TYPE	13	12	4	16

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S315. Gene #33: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
ATXN1 MUTATED	4	4	1
ATXN1 WILD-TYPE	17	13	16

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.87 (Fisher's exact test), Q value = 1

Table S316. Gene #33: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ATXN1 MUTATED	2	2	2	3	0
ATXN1 WILD-TYPE	11	16	6	11	2

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0468 (Fisher's exact test), Q value = 1

Table S317. Gene #33: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
ATXN1 MUTATED	0	4	4	1
ATXN1 WILD-TYPE	12	8	10	15

Figure S22. Get High-res Image Gene #33: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S318. Gene #33: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
ATXN1 MUTATED	2	2	2	1	2	0
ATXN1 WILD-TYPE	4	14	7	9	5	6

'AATK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0984 (Fisher's exact test), Q value = 1

Table S319. Gene #34: 'AATK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
AATK MUTATED	0	3	1	0	0	1	1
AATK WILD-TYPE	10	11	6	14	8	3	2

'AATK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S320. Gene #34: 'AATK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
AATK MUTATED	0	0	1	2	0	1	0
AATK WILD-TYPE	12	11	4	8	6	8	2

'AATK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.225 (Fisher's exact test), Q value = 1

Table S321. Gene #34: 'AATK MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
AATK MUTATED	0	2	1	1
AATK WILD-TYPE	16	7	12	15

'AATK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S322. Gene #34: 'AATK MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
AATK MUTATED	0	3	0	1
AATK WILD-TYPE	16	13	4	17

'AATK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S323. Gene #34: 'AATK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
AATK MUTATED	2	1	1
AATK WILD-TYPE	19	16	16

'AATK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S324. Gene #34: 'AATK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
AATK MUTATED	2	2	0	0	0
AATK WILD-TYPE	11	16	8	14	2

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S325. Gene #34: 'AATK MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
AATK MUTATED	0	1	2	1
AATK WILD-TYPE	12	11	12	15

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.741 (Fisher's exact test), Q value = 1

Table S326. Gene #34: 'AATK MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
AATK MUTATED	1	2	1	0	0	0
AATK WILD-TYPE	5	14	8	10	7	6

'ZNF628 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S327. Gene #35: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
ZNF628 MUTATED	2	1	0	2	2	0	0
ZNF628 WILD-TYPE	8	13	7	12	6	4	3

'ZNF628 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.85 (Fisher's exact test), Q value = 1

Table S328. Gene #35: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
ZNF628 MUTATED	2	2	0	1	0	0	0
ZNF628 WILD-TYPE	10	9	5	9	6	9	2

'ZNF628 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S329. Gene #35: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
ZNF628 MUTATED	1	1	0	1
ZNF628 WILD-TYPE	6	6	6	7

'ZNF628 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S330. Gene #35: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ZNF628 MUTATED	1	1	0	0	0	0	0	1
ZNF628 WILD-TYPE	4	5	5	3	3	1	3	1

'ZNF628 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.281 (Fisher's exact test), Q value = 1

Table S331. Gene #35: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
ZNF628 MUTATED	3	1	1	0
ZNF628 WILD-TYPE	13	8	12	16

'ZNF628 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.113 (Fisher's exact test), Q value = 1

Table S332. Gene #35: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZNF628 MUTATED	3	1	1	0
ZNF628 WILD-TYPE	13	15	3	18

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S333. Gene #35: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
ZNF628 MUTATED	1	3	1
ZNF628 WILD-TYPE	20	14	16

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.503 (Fisher's exact test), Q value = 1

Table S334. Gene #35: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZNF628 MUTATED	0	3	0	2	0
ZNF628 WILD-TYPE	13	15	8	12	2

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 1

Table S335. Gene #35: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
ZNF628 MUTATED	1	3	1	0
ZNF628 WILD-TYPE	11	9	13	16

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.67 (Fisher's exact test), Q value = 1

Table S336. Gene #35: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
ZNF628 MUTATED	0	2	0	2	1	0
ZNF628 WILD-TYPE	6	14	9	8	6	6

'KRTAP4-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S337. Gene #36: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
KRTAP4-5 MUTATED	1	3	0	1	0	0	0
KRTAP4-5 WILD-TYPE	9	11	7	13	8	4	3

'KRTAP4-5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S338. Gene #36: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
KRTAP4-5 MUTATED	1	1	1	0	0	1	0
KRTAP4-5 WILD-TYPE	11	10	4	10	6	8	2

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.905 (Fisher's exact test), Q value = 1

Table S339. Gene #36: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
KRTAP4-5 MUTATED	2	0	1	1
KRTAP4-5 WILD-TYPE	14	9	12	15

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S340. Gene #36: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KRTAP4-5 MUTATED	2	1	0	1
KRTAP4-5 WILD-TYPE	14	15	4	17

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S341. Gene #36: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
KRTAP4-5 MUTATED	2	1	1
KRTAP4-5 WILD-TYPE	19	16	16

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S342. Gene #36: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KRTAP4-5 MUTATED	1	1	0	2	0
KRTAP4-5 WILD-TYPE	12	17	8	12	2

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S343. Gene #36: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
KRTAP4-5 MUTATED	1	1	1	1
KRTAP4-5 WILD-TYPE	11	11	13	15

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.965 (Fisher's exact test), Q value = 1

Table S344. Gene #36: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
KRTAP4-5 MUTATED	0	1	1	1	1	0
KRTAP4-5 WILD-TYPE	6	15	8	9	6	6

'NOXA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.155 (Fisher's exact test), Q value = 1

Table S345. Gene #37: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
NOXA1 MUTATED	1	0	0	4	0	0	0
NOXA1 WILD-TYPE	9	14	7	10	8	4	3

'NOXA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.741 (Fisher's exact test), Q value = 1

Table S346. Gene #37: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
NOXA1 MUTATED	2	0	0	1	0	0	0
NOXA1 WILD-TYPE	10	11	5	9	6	9	2

'NOXA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.24 (Fisher's exact test), Q value = 1

Table S347. Gene #37: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
NOXA1 MUTATED	2	1	0	0
NOXA1 WILD-TYPE	14	8	13	16

'NOXA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S348. Gene #37: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NOXA1 MUTATED	2	1	0	0
NOXA1 WILD-TYPE	14	15	4	18

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.103 (Fisher's exact test), Q value = 1

Table S349. Gene #37: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
NOXA1 MUTATED	3	0	0
NOXA1 WILD-TYPE	18	17	17

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S350. Gene #37: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NOXA1 MUTATED	1	0	0	2	0
NOXA1 WILD-TYPE	12	18	8	12	2

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.193 (Fisher's exact test), Q value = 1

Table S351. Gene #37: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
NOXA1 MUTATED	2	0	1	0
NOXA1 WILD-TYPE	10	12	13	16

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.154 (Fisher's exact test), Q value = 1

Table S352. Gene #37: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
NOXA1 MUTATED	1	0	0	2	0	0
NOXA1 WILD-TYPE	5	16	9	8	7	6

'TRIOBP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.905 (Fisher's exact test), Q value = 1

Table S353. Gene #38: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
TRIOBP MUTATED	1	4	1	3	1	0	0
TRIOBP WILD-TYPE	9	10	6	11	7	4	3

'TRIOBP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.419 (Fisher's exact test), Q value = 1

Table S354. Gene #38: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
TRIOBP MUTATED	3	2	0	0	1	2	1
TRIOBP WILD-TYPE	9	9	5	10	5	7	1

'TRIOBP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S355. Gene #38: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
TRIOBP MUTATED	0	0	1	2
TRIOBP WILD-TYPE	7	7	5	6

'TRIOBP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.129 (Fisher's exact test), Q value = 1

Table S356. Gene #38: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TRIOBP MUTATED	1	0	0	0	0	0	2	0
TRIOBP WILD-TYPE	4	6	5	3	3	1	1	2

'TRIOBP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S357. Gene #38: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
TRIOBP MUTATED	2	1	2	3
TRIOBP WILD-TYPE	14	8	11	13

'TRIOBP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.111 (Fisher's exact test), Q value = 1

Table S358. Gene #38: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TRIOBP MUTATED	3	0	0	5
TRIOBP WILD-TYPE	13	16	4	13

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.533 (Fisher's exact test), Q value = 1

Table S359. Gene #38: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
TRIOBP MUTATED	2	3	4
TRIOBP WILD-TYPE	19	14	13

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.869 (Fisher's exact test), Q value = 1

Table S360. Gene #38: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TRIOBP MUTATED	2	2	2	3	0
TRIOBP WILD-TYPE	11	16	6	11	2

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S361. Gene #38: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
TRIOBP MUTATED	3	1	1	4
TRIOBP WILD-TYPE	9	11	13	12

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S362. Gene #38: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
TRIOBP MUTATED	1	2	1	2	1	2
TRIOBP WILD-TYPE	5	14	8	8	6	4

'ZNF598 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.649 (Fisher's exact test), Q value = 1

Table S363. Gene #39: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
ZNF598 MUTATED	2	1	2	4	2	0	1
ZNF598 WILD-TYPE	8	13	5	10	6	4	2

'ZNF598 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.773 (Fisher's exact test), Q value = 1

Table S364. Gene #39: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
ZNF598 MUTATED	3	3	0	2	0	1	0
ZNF598 WILD-TYPE	9	8	5	8	6	8	2

'ZNF598 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S365. Gene #39: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
ZNF598 MUTATED	3	1	1	1
ZNF598 WILD-TYPE	4	6	5	7

'ZNF598 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S366. Gene #39: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ZNF598 MUTATED	1	0	2	1	1	0	1	0
ZNF598 WILD-TYPE	4	6	3	2	2	1	2	2

'ZNF598 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S367. Gene #39: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
ZNF598 MUTATED	4	1	2	2
ZNF598 WILD-TYPE	12	8	11	14

'ZNF598 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.952 (Fisher's exact test), Q value = 1

Table S368. Gene #39: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZNF598 MUTATED	3	2	1	3
ZNF598 WILD-TYPE	13	14	3	15

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.901 (Fisher's exact test), Q value = 1

Table S369. Gene #39: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
ZNF598 MUTATED	4	2	3
ZNF598 WILD-TYPE	17	15	14

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.227 (Fisher's exact test), Q value = 1

Table S370. Gene #39: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZNF598 MUTATED	1	3	0	5	0
ZNF598 WILD-TYPE	12	15	8	9	2

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.177 (Fisher's exact test), Q value = 1

Table S371. Gene #39: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
ZNF598 MUTATED	4	0	2	3
ZNF598 WILD-TYPE	8	12	12	13

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.25 (Fisher's exact test), Q value = 1

Table S372. Gene #39: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
ZNF598 MUTATED	1	3	0	4	1	0
ZNF598 WILD-TYPE	5	13	9	6	6	6

'IRX3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.317 (Fisher's exact test), Q value = 1

Table S373. Gene #40: 'IRX3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
IRX3 MUTATED	2	0	0	1	2	0	0
IRX3 WILD-TYPE	8	14	7	13	6	4	3

'IRX3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 1

Table S374. Gene #40: 'IRX3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
IRX3 MUTATED	0	2	1	1	0	0	0
IRX3 WILD-TYPE	12	9	4	9	6	9	2

'IRX3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S375. Gene #40: 'IRX3 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
IRX3 MUTATED	2	1	1	0
IRX3 WILD-TYPE	14	8	12	16

'IRX3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S376. Gene #40: 'IRX3 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
IRX3 MUTATED	1	2	1	0
IRX3 WILD-TYPE	15	14	3	18

'IRX3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S377. Gene #40: 'IRX3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
IRX3 MUTATED	2	2	0
IRX3 WILD-TYPE	19	15	17

'IRX3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S378. Gene #40: 'IRX3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
IRX3 MUTATED	2	1	0	1	0
IRX3 WILD-TYPE	11	17	8	13	2

'IRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.17 (Fisher's exact test), Q value = 1

Table S379. Gene #40: 'IRX3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
IRX3 MUTATED	0	2	2	0
IRX3 WILD-TYPE	12	10	12	16

'IRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0829 (Fisher's exact test), Q value = 1

Table S380. Gene #40: 'IRX3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
IRX3 MUTATED	1	0	1	0	2	0
IRX3 WILD-TYPE	5	16	8	10	5	6

'WDR34 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.194 (Fisher's exact test), Q value = 1

Table S381. Gene #41: 'WDR34 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
WDR34 MUTATED	0	0	0	3	1	1	0
WDR34 WILD-TYPE	10	14	7	11	7	3	3

'WDR34 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.898 (Fisher's exact test), Q value = 1

Table S382. Gene #41: 'WDR34 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
WDR34 MUTATED	2	1	0	1	1	0	0
WDR34 WILD-TYPE	10	10	5	9	5	9	2

'WDR34 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.858 (Fisher's exact test), Q value = 1

Table S383. Gene #41: 'WDR34 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
WDR34 MUTATED	2	0	1	2
WDR34 WILD-TYPE	14	9	12	14

'WDR34 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S384. Gene #41: 'WDR34 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
WDR34 MUTATED	2	2	0	1
WDR34 WILD-TYPE	14	14	4	17

'WDR34 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S385. Gene #41: 'WDR34 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
WDR34 MUTATED	3	1	1
WDR34 WILD-TYPE	18	16	16

'WDR34 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S386. Gene #41: 'WDR34 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
WDR34 MUTATED	1	1	0	3	0
WDR34 WILD-TYPE	12	17	8	11	2

'WDR34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.223 (Fisher's exact test), Q value = 1

Table S387. Gene #41: 'WDR34 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
WDR34 MUTATED	3	0	1	1
WDR34 WILD-TYPE	9	12	13	15

'WDR34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0972 (Fisher's exact test), Q value = 1

Table S388. Gene #41: 'WDR34 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
WDR34 MUTATED	0	0	1	3	0	1
WDR34 WILD-TYPE	6	16	8	7	7	5

'BHLHE22 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.943 (Fisher's exact test), Q value = 1

Table S389. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
BHLHE22 MUTATED	1	2	1	1	0	0	0
BHLHE22 WILD-TYPE	9	12	6	13	8	4	3

'BHLHE22 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.294 (Fisher's exact test), Q value = 1

Table S390. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
BHLHE22 MUTATED	0	1	1	1	0	1	1
BHLHE22 WILD-TYPE	12	10	4	9	6	8	1

'BHLHE22 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S391. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
BHLHE22 MUTATED	2	1	0	1
BHLHE22 WILD-TYPE	5	6	6	7

'BHLHE22 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.916 (Fisher's exact test), Q value = 1

Table S392. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
BHLHE22 MUTATED	2	1	1	0	0	0	0	0
BHLHE22 WILD-TYPE	3	5	4	3	3	1	3	2

'BHLHE22 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0459 (Fisher's exact test), Q value = 1

Table S393. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
BHLHE22 MUTATED	0	3	1	1
BHLHE22 WILD-TYPE	16	6	12	15

Figure S23. Get High-res Image Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'BHLHE22 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S394. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
BHLHE22 MUTATED	2	2	0	1
BHLHE22 WILD-TYPE	14	14	4	17

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S395. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
BHLHE22 MUTATED	2	2	1
BHLHE22 WILD-TYPE	19	15	16

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.835 (Fisher's exact test), Q value = 1

Table S396. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
BHLHE22 MUTATED	2	2	0	1	0
BHLHE22 WILD-TYPE	11	16	8	13	2

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S397. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
BHLHE22 MUTATED	0	2	2	1
BHLHE22 WILD-TYPE	12	10	12	15

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S398. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
BHLHE22 MUTATED	1	2	1	0	1	0
BHLHE22 WILD-TYPE	5	14	8	10	6	6

'PANK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.768 (Fisher's exact test), Q value = 1

Table S399. Gene #43: 'PANK2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
PANK2 MUTATED	1	0	1	2	1	0	0
PANK2 WILD-TYPE	9	14	6	12	7	4	3

'PANK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S400. Gene #43: 'PANK2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
PANK2 MUTATED	2	1	0	0	0	0	0
PANK2 WILD-TYPE	10	10	5	10	6	9	2

'PANK2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S401. Gene #43: 'PANK2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
PANK2 MUTATED	1	0	0	2
PANK2 WILD-TYPE	6	7	6	6

'PANK2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S402. Gene #43: 'PANK2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
PANK2 MUTATED	2	0	0	0	1	0	0	0
PANK2 WILD-TYPE	3	6	5	3	2	1	3	2

'PANK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0793 (Fisher's exact test), Q value = 1

Table S403. Gene #43: 'PANK2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
PANK2 MUTATED	3	0	0	0
PANK2 WILD-TYPE	13	9	13	16

'PANK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.05 (Fisher's exact test), Q value = 1

Table S404. Gene #43: 'PANK2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PANK2 MUTATED	2	0	1	0
PANK2 WILD-TYPE	14	16	3	18

'PANK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S405. Gene #43: 'PANK2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
PANK2 MUTATED	2	1	0
PANK2 WILD-TYPE	19	16	17

'PANK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S406. Gene #43: 'PANK2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PANK2 MUTATED	1	0	0	2	0
PANK2 WILD-TYPE	12	18	8	12	2

'PANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0176 (Fisher's exact test), Q value = 1

Table S407. Gene #43: 'PANK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
PANK2 MUTATED	3	0	0	0
PANK2 WILD-TYPE	9	12	14	16

Figure S24. Get High-res Image Gene #43: 'PANK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'PANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.305 (Fisher's exact test), Q value = 1

Table S408. Gene #43: 'PANK2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
PANK2 MUTATED	1	0	0	1	1	0
PANK2 WILD-TYPE	5	16	9	9	6	6

'FPGS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S409. Gene #44: 'FPGS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
FPGS MUTATED	0	2	0	3	0	0	0
FPGS WILD-TYPE	10	12	7	11	8	4	3

'FPGS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0904 (Fisher's exact test), Q value = 1

Table S410. Gene #44: 'FPGS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
FPGS MUTATED	1	0	0	0	0	2	1
FPGS WILD-TYPE	11	11	5	10	6	7	1

'FPGS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S411. Gene #44: 'FPGS MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
FPGS MUTATED	0	0	1	2
FPGS WILD-TYPE	7	7	5	6

'FPGS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S412. Gene #44: 'FPGS MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
FPGS MUTATED	1	1	0	0	0	1	0	0
FPGS WILD-TYPE	4	5	5	3	3	0	3	2

'FPGS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.686 (Fisher's exact test), Q value = 1

Table S413. Gene #44: 'FPGS MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
FPGS MUTATED	1	1	0	2
FPGS WILD-TYPE	15	8	13	14

'FPGS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S414. Gene #44: 'FPGS MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
FPGS MUTATED	2	0	0	2
FPGS WILD-TYPE	14	16	4	16

'FPGS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.238 (Fisher's exact test), Q value = 1

Table S415. Gene #44: 'FPGS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
FPGS MUTATED	0	2	2
FPGS WILD-TYPE	21	15	15

'FPGS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S416. Gene #44: 'FPGS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
FPGS MUTATED	0	2	0	2	0
FPGS WILD-TYPE	13	16	8	12	2

'FPGS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.659 (Fisher's exact test), Q value = 1

Table S417. Gene #44: 'FPGS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
FPGS MUTATED	1	1	0	2
FPGS WILD-TYPE	11	11	14	14

'FPGS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S418. Gene #44: 'FPGS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
FPGS MUTATED	0	2	0	1	1	0
FPGS WILD-TYPE	6	14	9	9	6	6

'GLTPD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0989 (Fisher's exact test), Q value = 1

Table S419. Gene #45: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
GLTPD2 MUTATED	1	0	0	1	3	1	0
GLTPD2 WILD-TYPE	9	14	7	13	5	3	3

'GLTPD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.826 (Fisher's exact test), Q value = 1

Table S420. Gene #45: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
GLTPD2 MUTATED	1	2	1	1	1	0	0
GLTPD2 WILD-TYPE	11	9	4	9	5	9	2

'GLTPD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.83 (Fisher's exact test), Q value = 1

Table S421. Gene #45: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
GLTPD2 MUTATED	2	0	2	2
GLTPD2 WILD-TYPE	14	9	11	14

'GLTPD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S422. Gene #45: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
GLTPD2 MUTATED	1	3	1	1
GLTPD2 WILD-TYPE	15	13	3	17

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.866 (Fisher's exact test), Q value = 1

Table S423. Gene #45: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
GLTPD2 MUTATED	3	2	1
GLTPD2 WILD-TYPE	18	15	16

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.533 (Fisher's exact test), Q value = 1

Table S424. Gene #45: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
GLTPD2 MUTATED	2	1	0	3	0
GLTPD2 WILD-TYPE	11	17	8	11	2

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 1

Table S425. Gene #45: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
GLTPD2 MUTATED	2	0	3	1
GLTPD2 WILD-TYPE	10	12	11	15

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.228 (Fisher's exact test), Q value = 1

Table S426. Gene #45: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
GLTPD2 MUTATED	0	0	2	2	1	1
GLTPD2 WILD-TYPE	6	16	7	8	6	5

'TNIP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.845 (Fisher's exact test), Q value = 1

Table S427. Gene #46: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
TNIP2 MUTATED	1	1	0	1	1	1	0
TNIP2 WILD-TYPE	9	13	7	13	7	3	3

'TNIP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 1

Table S428. Gene #46: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
TNIP2 MUTATED	1	0	1	2	0	0	0
TNIP2 WILD-TYPE	11	11	4	8	6	9	2

'TNIP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.746 (Fisher's exact test), Q value = 1

Table S429. Gene #46: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
TNIP2 MUTATED	1	0	2	1
TNIP2 WILD-TYPE	15	9	11	15

'TNIP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S430. Gene #46: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TNIP2 MUTATED	1	2	0	1
TNIP2 WILD-TYPE	15	14	4	17

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S431. Gene #46: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
TNIP2 MUTATED	1	2	1
TNIP2 WILD-TYPE	20	15	16

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.413 (Fisher's exact test), Q value = 1

Table S432. Gene #46: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TNIP2 MUTATED	1	0	1	2	0
TNIP2 WILD-TYPE	12	18	7	12	2

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S433. Gene #46: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
TNIP2 MUTATED	2	0	1	1
TNIP2 WILD-TYPE	10	12	13	15

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.265 (Fisher's exact test), Q value = 1

Table S434. Gene #46: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
TNIP2 MUTATED	0	0	1	2	0	1
TNIP2 WILD-TYPE	6	16	8	8	7	5

'AKAP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0709 (Fisher's exact test), Q value = 1

Table S435. Gene #47: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
AKAP2 MUTATED	1	1	0	0	3	0	1
AKAP2 WILD-TYPE	9	13	7	14	5	4	2

'AKAP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S436. Gene #47: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
AKAP2 MUTATED	1	2	1	1	1	0	0
AKAP2 WILD-TYPE	11	9	4	9	5	9	2

'AKAP2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.917 (Fisher's exact test), Q value = 1

Table S437. Gene #47: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
AKAP2 MUTATED	1	2	1	1
AKAP2 WILD-TYPE	6	5	5	7

'AKAP2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S438. Gene #47: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
AKAP2 MUTATED	1	1	2	0	0	0	0	1
AKAP2 WILD-TYPE	4	5	3	3	3	1	3	1

'AKAP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.829 (Fisher's exact test), Q value = 1

Table S439. Gene #47: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
AKAP2 MUTATED	2	0	2	2
AKAP2 WILD-TYPE	14	9	11	14

'AKAP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S440. Gene #47: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
AKAP2 MUTATED	1	2	1	2
AKAP2 WILD-TYPE	15	14	3	16

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.656 (Fisher's exact test), Q value = 1

Table S441. Gene #47: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
AKAP2 MUTATED	2	1	3
AKAP2 WILD-TYPE	19	16	14

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 1

Table S442. Gene #47: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
AKAP2 MUTATED	2	4	0	0	0
AKAP2 WILD-TYPE	11	14	8	14	2

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.94 (Fisher's exact test), Q value = 1

Table S443. Gene #47: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
AKAP2 MUTATED	1	2	1	2
AKAP2 WILD-TYPE	11	10	13	14

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.707 (Fisher's exact test), Q value = 1

Table S444. Gene #47: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
AKAP2 MUTATED	1	3	1	0	1	0
AKAP2 WILD-TYPE	5	13	8	10	6	6

'RREB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.278 (Fisher's exact test), Q value = 1

Table S445. Gene #48: 'RREB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
RREB1 MUTATED	0	0	2	2	1	0	0
RREB1 WILD-TYPE	10	14	5	12	7	4	3

'RREB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.86 (Fisher's exact test), Q value = 1

Table S446. Gene #48: 'RREB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
RREB1 MUTATED	2	1	0	0	0	1	0
RREB1 WILD-TYPE	10	10	5	10	6	8	2

'RREB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.619 (Fisher's exact test), Q value = 1

Table S447. Gene #48: 'RREB1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
RREB1 MUTATED	1	1	1	0
RREB1 WILD-TYPE	15	8	12	16

'RREB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S448. Gene #48: 'RREB1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RREB1 MUTATED	1	1	0	1
RREB1 WILD-TYPE	15	15	4	17

'RREB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 1

Table S449. Gene #48: 'RREB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
RREB1 MUTATED	0	2	2
RREB1 WILD-TYPE	21	15	15

'RREB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S450. Gene #48: 'RREB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RREB1 MUTATED	2	2	0	0	0
RREB1 WILD-TYPE	11	16	8	14	2

'RREB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.286 (Fisher's exact test), Q value = 1

Table S451. Gene #48: 'RREB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
RREB1 MUTATED	2	0	0	2
RREB1 WILD-TYPE	10	12	14	14

'RREB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S452. Gene #48: 'RREB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
RREB1 MUTATED	1	2	0	0	0	1
RREB1 WILD-TYPE	5	14	9	10	7	5

'TPO MUTATION STATUS' versus 'CN_CNMF'

P value = 0.283 (Fisher's exact test), Q value = 1

Table S453. Gene #49: 'TPO MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
TPO MUTATED	4	1	1	2	2	2	0
TPO WILD-TYPE	6	13	6	12	6	2	3

'TPO MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.527 (Fisher's exact test), Q value = 1

Table S454. Gene #49: 'TPO MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
TPO MUTATED	3	2	1	1	1	0	1
TPO WILD-TYPE	9	9	4	9	5	9	1

'TPO MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.886 (Fisher's exact test), Q value = 1

Table S455. Gene #49: 'TPO MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
TPO MUTATED	1	1	0	2
TPO WILD-TYPE	6	6	6	6

'TPO MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.693 (Fisher's exact test), Q value = 1

Table S456. Gene #49: 'TPO MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TPO MUTATED	2	1	0	0	1	0	0	0
TPO WILD-TYPE	3	5	5	3	2	1	3	2

'TPO MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.221 (Fisher's exact test), Q value = 1

Table S457. Gene #49: 'TPO MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
TPO MUTATED	5	2	1	1
TPO WILD-TYPE	11	7	12	15

'TPO MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S458. Gene #49: 'TPO MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TPO MUTATED	4	2	2	1
TPO WILD-TYPE	12	14	2	17

'TPO MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.221 (Fisher's exact test), Q value = 1

Table S459. Gene #49: 'TPO MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
TPO MUTATED	3	5	1
TPO WILD-TYPE	18	12	16

'TPO MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S460. Gene #49: 'TPO MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TPO MUTATED	1	2	1	5	0
TPO WILD-TYPE	12	16	7	9	2

'TPO MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S461. Gene #49: 'TPO MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
TPO MUTATED	3	3	2	1
TPO WILD-TYPE	9	9	12	15

'TPO MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.195 (Fisher's exact test), Q value = 1

Table S462. Gene #49: 'TPO MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
TPO MUTATED	0	1	1	3	3	1
TPO WILD-TYPE	6	15	8	7	4	5

'OBSCN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.963 (Fisher's exact test), Q value = 1

Table S463. Gene #50: 'OBSCN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
OBSCN MUTATED	4	4	2	5	2	1	0
OBSCN WILD-TYPE	6	10	5	9	6	3	3

'OBSCN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S464. Gene #50: 'OBSCN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
OBSCN MUTATED	3	4	2	2	2	1	2
OBSCN WILD-TYPE	9	7	3	8	4	8	0

'OBSCN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S465. Gene #50: 'OBSCN MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
OBSCN MUTATED	2	1	2	3
OBSCN WILD-TYPE	5	6	4	5

'OBSCN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S466. Gene #50: 'OBSCN MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
OBSCN MUTATED	1	2	1	0	2	0	2	0
OBSCN WILD-TYPE	4	4	4	3	1	1	1	2

'OBSCN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.568 (Fisher's exact test), Q value = 1

Table S467. Gene #50: 'OBSCN MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
OBSCN MUTATED	6	2	5	3
OBSCN WILD-TYPE	10	7	8	13

'OBSCN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.808 (Fisher's exact test), Q value = 1

Table S468. Gene #50: 'OBSCN MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
OBSCN MUTATED	5	4	2	5
OBSCN WILD-TYPE	11	12	2	13

'OBSCN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 1

Table S469. Gene #50: 'OBSCN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
OBSCN MUTATED	4	8	4
OBSCN WILD-TYPE	17	9	13

'OBSCN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.497 (Fisher's exact test), Q value = 1

Table S470. Gene #50: 'OBSCN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
OBSCN MUTATED	2	5	3	6	0
OBSCN WILD-TYPE	11	13	5	8	2

'OBSCN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.956 (Fisher's exact test), Q value = 1

Table S471. Gene #50: 'OBSCN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
OBSCN MUTATED	4	4	4	4
OBSCN WILD-TYPE	8	8	10	12

'OBSCN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S472. Gene #50: 'OBSCN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
OBSCN MUTATED	0	4	3	4	3	2
OBSCN WILD-TYPE	6	12	6	6	4	4

'SNED1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S473. Gene #51: 'SNED1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
SNED1 MUTATED	2	0	1	1	0	1	0
SNED1 WILD-TYPE	8	14	6	13	8	3	3

'SNED1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.899 (Fisher's exact test), Q value = 1

Table S474. Gene #51: 'SNED1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
SNED1 MUTATED	2	1	0	1	1	0	0
SNED1 WILD-TYPE	10	10	5	9	5	9	2

'SNED1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S475. Gene #51: 'SNED1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
SNED1 MUTATED	3	1	0	1
SNED1 WILD-TYPE	13	8	13	15

'SNED1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.668 (Fisher's exact test), Q value = 1

Table S476. Gene #51: 'SNED1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SNED1 MUTATED	3	1	0	1
SNED1 WILD-TYPE	13	15	4	17

'SNED1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0327 (Fisher's exact test), Q value = 1

Table S477. Gene #51: 'SNED1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
SNED1 MUTATED	0	4	1
SNED1 WILD-TYPE	21	13	16

Figure S25. Get High-res Image Gene #51: 'SNED1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'SNED1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S478. Gene #51: 'SNED1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SNED1 MUTATED	0	2	1	2	0
SNED1 WILD-TYPE	13	16	7	12	2

'SNED1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.298 (Fisher's exact test), Q value = 1

Table S479. Gene #51: 'SNED1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
SNED1 MUTATED	2	2	0	1
SNED1 WILD-TYPE	10	10	14	15

'SNED1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S480. Gene #51: 'SNED1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
SNED1 MUTATED	0	2	0	1	1	1
SNED1 WILD-TYPE	6	14	9	9	6	5

'MEN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 1

Table S481. Gene #52: 'MEN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
MEN1 MUTATED	0	1	1	0	2	0	0
MEN1 WILD-TYPE	10	13	6	14	6	4	3

'MEN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0178 (Fisher's exact test), Q value = 1

Table S482. Gene #52: 'MEN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
MEN1 MUTATED	0	0	2	3	0	0	0
MEN1 WILD-TYPE	12	11	3	7	6	9	2

Figure S26. Get High-res Image Gene #52: 'MEN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'MEN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0189 (Fisher's exact test), Q value = 1

Table S483. Gene #52: 'MEN1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
MEN1 MUTATED	0	2	3	0
MEN1 WILD-TYPE	16	7	10	16

Figure S27. Get High-res Image Gene #52: 'MEN1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'MEN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00659 (Fisher's exact test), Q value = 1

Table S484. Gene #52: 'MEN1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MEN1 MUTATED	0	5	0	0
MEN1 WILD-TYPE	16	11	4	18

Figure S28. Get High-res Image Gene #52: 'MEN1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'MEN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S485. Gene #52: 'MEN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
MEN1 MUTATED	4	1	0
MEN1 WILD-TYPE	17	16	17

'MEN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0428 (Fisher's exact test), Q value = 1

Table S486. Gene #52: 'MEN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MEN1 MUTATED	4	0	0	1	0
MEN1 WILD-TYPE	9	18	8	13	2

Figure S29. Get High-res Image Gene #52: 'MEN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'MEN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0241 (Fisher's exact test), Q value = 1

Table S487. Gene #52: 'MEN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
MEN1 MUTATED	1	0	4	0
MEN1 WILD-TYPE	11	12	10	16

Figure S30. Get High-res Image Gene #52: 'MEN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'MEN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0755 (Fisher's exact test), Q value = 1

Table S488. Gene #52: 'MEN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
MEN1 MUTATED	2	0	2	1	0	0
MEN1 WILD-TYPE	4	16	7	9	7	6

'BTBD11 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S489. Gene #53: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
BTBD11 MUTATED	1	2	1	1	1	0	0
BTBD11 WILD-TYPE	9	12	6	13	7	4	3

'BTBD11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.884 (Fisher's exact test), Q value = 1

Table S490. Gene #53: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
BTBD11 MUTATED	1	1	1	1	1	0	0
BTBD11 WILD-TYPE	11	10	4	9	5	9	2

'BTBD11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.798 (Fisher's exact test), Q value = 1

Table S491. Gene #53: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
BTBD11 MUTATED	1	1	2	1
BTBD11 WILD-TYPE	15	8	11	15

'BTBD11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S492. Gene #53: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
BTBD11 MUTATED	1	2	0	2
BTBD11 WILD-TYPE	15	14	4	16

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S493. Gene #53: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
BTBD11 MUTATED	4	0	1
BTBD11 WILD-TYPE	17	17	16

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.184 (Fisher's exact test), Q value = 1

Table S494. Gene #53: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
BTBD11 MUTATED	2	0	2	1	0
BTBD11 WILD-TYPE	11	18	6	13	2

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S495. Gene #53: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
BTBD11 MUTATED	1	0	3	1
BTBD11 WILD-TYPE	11	12	11	15

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.237 (Fisher's exact test), Q value = 1

Table S496. Gene #53: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
BTBD11 MUTATED	1	0	2	1	0	1
BTBD11 WILD-TYPE	5	16	7	9	7	5

'RNF149 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 1

Table S497. Gene #54: 'RNF149 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
RNF149 MUTATED	0	1	1	0	1	0	1
RNF149 WILD-TYPE	10	13	6	14	7	4	2

'RNF149 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0608 (Fisher's exact test), Q value = 1

Table S498. Gene #54: 'RNF149 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
RNF149 MUTATED	0	0	0	2	2	0	0
RNF149 WILD-TYPE	12	11	5	8	4	9	2

'RNF149 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S499. Gene #54: 'RNF149 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
RNF149 MUTATED	1	1	1	0
RNF149 WILD-TYPE	6	6	5	8

'RNF149 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.954 (Fisher's exact test), Q value = 1

Table S500. Gene #54: 'RNF149 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
RNF149 MUTATED	0	1	1	0	1	0	0	0
RNF149 WILD-TYPE	5	5	4	3	2	1	3	2

'RNF149 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S501. Gene #54: 'RNF149 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
RNF149 MUTATED	0	1	2	1
RNF149 WILD-TYPE	16	8	11	15

'RNF149 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S502. Gene #54: 'RNF149 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RNF149 MUTATED	0	2	0	2
RNF149 WILD-TYPE	16	14	4	16

'RNF149 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S503. Gene #54: 'RNF149 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
RNF149 MUTATED	1	2	1
RNF149 WILD-TYPE	20	15	16

'RNF149 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.26 (Fisher's exact test), Q value = 1

Table S504. Gene #54: 'RNF149 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RNF149 MUTATED	0	3	1	0	0
RNF149 WILD-TYPE	13	15	7	14	2

'RNF149 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S505. Gene #54: 'RNF149 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
RNF149 MUTATED	0	2	1	1
RNF149 WILD-TYPE	12	10	13	15

'RNF149 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S506. Gene #54: 'RNF149 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
RNF149 MUTATED	0	3	1	0	0	0
RNF149 WILD-TYPE	6	13	8	10	7	6

'KIAA1984 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.149 (Fisher's exact test), Q value = 1

Table S507. Gene #55: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
KIAA1984 MUTATED	1	0	2	0	1	0	0
KIAA1984 WILD-TYPE	9	14	5	14	7	4	3

'KIAA1984 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.117 (Fisher's exact test), Q value = 1

Table S508. Gene #55: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
KIAA1984 MUTATED	0	1	0	2	0	0	1
KIAA1984 WILD-TYPE	12	10	5	8	6	9	1

'KIAA1984 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S509. Gene #55: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
KIAA1984 MUTATED	1	1	0	1
KIAA1984 WILD-TYPE	6	6	6	7

'KIAA1984 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.506 (Fisher's exact test), Q value = 1

Table S510. Gene #55: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
KIAA1984 MUTATED	0	2	0	0	1	0	0	0
KIAA1984 WILD-TYPE	5	4	5	3	2	1	3	2

'KIAA1984 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.103 (Fisher's exact test), Q value = 1

Table S511. Gene #55: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
KIAA1984 MUTATED	1	0	3	0
KIAA1984 WILD-TYPE	15	9	10	16

'KIAA1984 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0496 (Fisher's exact test), Q value = 1

Table S512. Gene #55: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KIAA1984 MUTATED	0	3	1	0
KIAA1984 WILD-TYPE	16	13	3	18

Figure S31. Get High-res Image Gene #55: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.18 (Fisher's exact test), Q value = 1

Table S513. Gene #55: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
KIAA1984 MUTATED	1	3	0
KIAA1984 WILD-TYPE	20	14	17

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S514. Gene #55: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KIAA1984 MUTATED	0	1	1	2	0
KIAA1984 WILD-TYPE	13	17	7	12	2

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.389 (Fisher's exact test), Q value = 1

Table S515. Gene #55: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
KIAA1984 MUTATED	2	1	1	0
KIAA1984 WILD-TYPE	10	11	13	16

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.967 (Fisher's exact test), Q value = 1

Table S516. Gene #55: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
KIAA1984 MUTATED	0	1	1	1	1	0
KIAA1984 WILD-TYPE	6	15	8	9	6	6

'CCDC150 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S517. Gene #56: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
CCDC150 MUTATED	2	0	0	1	1	0	0
CCDC150 WILD-TYPE	8	14	7	13	7	4	3

'CCDC150 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S518. Gene #56: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
CCDC150 MUTATED	2	1	1	0	0	0	0
CCDC150 WILD-TYPE	10	10	4	10	6	9	2

'CCDC150 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S519. Gene #56: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
CCDC150 MUTATED	1	1	0	1
CCDC150 WILD-TYPE	6	6	6	7

'CCDC150 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.602 (Fisher's exact test), Q value = 1

Table S520. Gene #56: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CCDC150 MUTATED	0	1	0	1	1	0	0	0
CCDC150 WILD-TYPE	5	5	5	2	2	1	3	2

'CCDC150 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.178 (Fisher's exact test), Q value = 1

Table S521. Gene #56: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
CCDC150 MUTATED	3	0	1	0
CCDC150 WILD-TYPE	13	9	12	16

'CCDC150 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.117 (Fisher's exact test), Q value = 1

Table S522. Gene #56: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CCDC150 MUTATED	2	1	1	0
CCDC150 WILD-TYPE	14	15	3	18

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.535 (Fisher's exact test), Q value = 1

Table S523. Gene #56: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
CCDC150 MUTATED	2	2	0
CCDC150 WILD-TYPE	19	15	17

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S524. Gene #56: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CCDC150 MUTATED	1	0	0	3	0
CCDC150 WILD-TYPE	12	18	8	11	2

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.169 (Fisher's exact test), Q value = 1

Table S525. Gene #56: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
CCDC150 MUTATED	2	0	2	0
CCDC150 WILD-TYPE	10	12	12	16

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.299 (Fisher's exact test), Q value = 1

Table S526. Gene #56: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
CCDC150 MUTATED	0	0	1	2	1	0
CCDC150 WILD-TYPE	6	16	8	8	6	6

'FAM18B2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.23 (Fisher's exact test), Q value = 1

Table S527. Gene #57: 'FAM18B2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
FAM18B2 MUTATED	2	0	1	0	1	0	0
FAM18B2 WILD-TYPE	8	14	6	14	7	4	3

'FAM18B2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.966 (Fisher's exact test), Q value = 1

Table S528. Gene #57: 'FAM18B2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
FAM18B2 MUTATED	1	1	0	1	1	0	0
FAM18B2 WILD-TYPE	11	10	5	9	5	9	2

'FAM18B2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.223 (Fisher's exact test), Q value = 1

Table S529. Gene #57: 'FAM18B2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
FAM18B2 MUTATED	1	2	1	0
FAM18B2 WILD-TYPE	15	7	12	16

'FAM18B2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S530. Gene #57: 'FAM18B2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
FAM18B2 MUTATED	2	2	0	0
FAM18B2 WILD-TYPE	14	14	4	18

'FAM18B2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0973 (Fisher's exact test), Q value = 1

Table S531. Gene #57: 'FAM18B2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
FAM18B2 MUTATED	0	3	1
FAM18B2 WILD-TYPE	21	14	16

'FAM18B2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S532. Gene #57: 'FAM18B2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
FAM18B2 MUTATED	0	3	0	1	0
FAM18B2 WILD-TYPE	13	15	8	13	2

'FAM18B2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0286 (Fisher's exact test), Q value = 1

Table S533. Gene #57: 'FAM18B2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
FAM18B2 MUTATED	1	3	0	0
FAM18B2 WILD-TYPE	11	9	14	16

Figure S32. Get High-res Image Gene #57: 'FAM18B2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'FAM18B2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S534. Gene #57: 'FAM18B2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
FAM18B2 MUTATED	0	3	0	1	0	0
FAM18B2 WILD-TYPE	6	13	9	9	7	6

'MUC5B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.997 (Fisher's exact test), Q value = 1

Table S535. Gene #58: 'MUC5B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
MUC5B MUTATED	3	5	2	6	3	1	1
MUC5B WILD-TYPE	7	9	5	8	5	3	2

'MUC5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 1

Table S536. Gene #58: 'MUC5B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
MUC5B MUTATED	2	5	2	5	3	1	2
MUC5B WILD-TYPE	10	6	3	5	3	8	0

'MUC5B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.538 (Fisher's exact test), Q value = 1

Table S537. Gene #58: 'MUC5B MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
MUC5B MUTATED	2	2	4	3
MUC5B WILD-TYPE	5	5	2	5

'MUC5B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S538. Gene #58: 'MUC5B MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
MUC5B MUTATED	2	2	2	0	2	0	2	1
MUC5B WILD-TYPE	3	4	3	3	1	1	1	1

'MUC5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S539. Gene #58: 'MUC5B MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
MUC5B MUTATED	5	4	6	5
MUC5B WILD-TYPE	11	5	7	11

'MUC5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.67 (Fisher's exact test), Q value = 1

Table S540. Gene #58: 'MUC5B MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MUC5B MUTATED	4	7	2	7
MUC5B WILD-TYPE	12	9	2	11

'MUC5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S541. Gene #58: 'MUC5B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
MUC5B MUTATED	7	6	7
MUC5B WILD-TYPE	14	11	10

'MUC5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S542. Gene #58: 'MUC5B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MUC5B MUTATED	3	7	4	6	0
MUC5B WILD-TYPE	10	11	4	8	2

'MUC5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S543. Gene #58: 'MUC5B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
MUC5B MUTATED	3	5	5	6
MUC5B WILD-TYPE	9	7	9	10

'MUC5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.967 (Fisher's exact test), Q value = 1

Table S544. Gene #58: 'MUC5B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
MUC5B MUTATED	2	6	2	4	3	2
MUC5B WILD-TYPE	4	10	7	6	4	4

'PTPLA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.231 (Fisher's exact test), Q value = 1

Table S545. Gene #59: 'PTPLA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
PTPLA MUTATED	2	0	1	0	1	0	0
PTPLA WILD-TYPE	8	14	6	14	7	4	3

'PTPLA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S546. Gene #59: 'PTPLA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
PTPLA MUTATED	0	1	0	2	0	0	0
PTPLA WILD-TYPE	12	10	5	8	6	9	2

'PTPLA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S547. Gene #59: 'PTPLA MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
PTPLA MUTATED	1	1	1	0
PTPLA WILD-TYPE	15	8	12	16

'PTPLA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S548. Gene #59: 'PTPLA MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PTPLA MUTATED	1	2	0	0
PTPLA WILD-TYPE	15	14	4	18

'PTPLA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S549. Gene #59: 'PTPLA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
PTPLA MUTATED	1	1	1
PTPLA WILD-TYPE	20	16	16

'PTPLA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S550. Gene #59: 'PTPLA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PTPLA MUTATED	1	1	0	1	0
PTPLA WILD-TYPE	12	17	8	13	2

'PTPLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.193 (Fisher's exact test), Q value = 1

Table S551. Gene #59: 'PTPLA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
PTPLA MUTATED	0	2	1	0
PTPLA WILD-TYPE	12	10	13	16

'PTPLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.497 (Fisher's exact test), Q value = 1

Table S552. Gene #59: 'PTPLA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
PTPLA MUTATED	1	1	0	0	1	0
PTPLA WILD-TYPE	5	15	9	10	6	6

'SRPX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.661 (Fisher's exact test), Q value = 1

Table S553. Gene #60: 'SRPX MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
SRPX MUTATED	1	2	0	0	0	0	0
SRPX WILD-TYPE	9	12	7	14	8	4	3

'SRPX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S554. Gene #60: 'SRPX MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
SRPX MUTATED	0	1	1	0	0	1	0
SRPX WILD-TYPE	12	10	4	10	6	8	2

'SRPX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S555. Gene #60: 'SRPX MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
SRPX MUTATED	0	1	1	1
SRPX WILD-TYPE	16	8	12	15

'SRPX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S556. Gene #60: 'SRPX MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SRPX MUTATED	1	1	0	1
SRPX WILD-TYPE	15	15	4	17

'SRPX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S557. Gene #60: 'SRPX MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
SRPX MUTATED	1	1	1
SRPX WILD-TYPE	20	16	16

'SRPX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.718 (Fisher's exact test), Q value = 1

Table S558. Gene #60: 'SRPX MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SRPX MUTATED	1	2	0	0	0
SRPX WILD-TYPE	12	16	8	14	2

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S559. Gene #60: 'SRPX MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
SRPX MUTATED	0	1	1	1
SRPX WILD-TYPE	12	11	13	15

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S560. Gene #60: 'SRPX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
SRPX MUTATED	0	2	1	0	0	0
SRPX WILD-TYPE	6	14	8	10	7	6

'GARS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S561. Gene #61: 'GARS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
GARS MUTATED	2	3	2	4	4	3	1
GARS WILD-TYPE	8	11	5	10	4	1	2

'GARS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.228 (Fisher's exact test), Q value = 1

Table S562. Gene #61: 'GARS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
GARS MUTATED	2	5	0	4	3	1	0
GARS WILD-TYPE	10	6	5	6	3	8	2

'GARS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.517 (Fisher's exact test), Q value = 1

Table S563. Gene #61: 'GARS MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
GARS MUTATED	3	1	3	2
GARS WILD-TYPE	4	6	3	6

'GARS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.335 (Fisher's exact test), Q value = 1

Table S564. Gene #61: 'GARS MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
GARS MUTATED	2	1	4	1	0	0	1	0
GARS WILD-TYPE	3	5	1	2	3	1	2	2

'GARS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.308 (Fisher's exact test), Q value = 1

Table S565. Gene #61: 'GARS MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
GARS MUTATED	3	1	4	7
GARS WILD-TYPE	13	8	9	9

'GARS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.102 (Fisher's exact test), Q value = 1

Table S566. Gene #61: 'GARS MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
GARS MUTATED	2	3	2	8
GARS WILD-TYPE	14	13	2	10

'GARS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0744 (Fisher's exact test), Q value = 1

Table S567. Gene #61: 'GARS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
GARS MUTATED	5	2	8
GARS WILD-TYPE	16	15	9

'GARS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S568. Gene #61: 'GARS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
GARS MUTATED	3	6	4	2	0
GARS WILD-TYPE	10	12	4	12	2

'GARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S569. Gene #61: 'GARS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
GARS MUTATED	2	2	3	8
GARS WILD-TYPE	10	10	11	8

'GARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S570. Gene #61: 'GARS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
GARS MUTATED	2	6	2	1	1	3
GARS WILD-TYPE	4	10	7	9	6	3

'PRSS27 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0865 (Fisher's exact test), Q value = 1

Table S571. Gene #62: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
PRSS27 MUTATED	1	0	2	0	0	0	0
PRSS27 WILD-TYPE	9	14	5	14	8	4	3

'PRSS27 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.74 (Fisher's exact test), Q value = 1

Table S572. Gene #62: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
PRSS27 MUTATED	0	1	0	1	1	0	0
PRSS27 WILD-TYPE	12	10	5	9	5	9	2

'PRSS27 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.127 (Fisher's exact test), Q value = 1

Table S573. Gene #62: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
PRSS27 MUTATED	1	2	0	0
PRSS27 WILD-TYPE	15	7	13	16

'PRSS27 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0502 (Fisher's exact test), Q value = 1

Table S574. Gene #62: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PRSS27 MUTATED	0	2	1	0
PRSS27 WILD-TYPE	16	14	3	18

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S575. Gene #62: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
PRSS27 MUTATED	1	2	0
PRSS27 WILD-TYPE	20	15	17

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S576. Gene #62: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PRSS27 MUTATED	1	1	0	1	0
PRSS27 WILD-TYPE	12	17	8	13	2

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.69 (Fisher's exact test), Q value = 1

Table S577. Gene #62: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
PRSS27 MUTATED	1	1	1	0
PRSS27 WILD-TYPE	11	11	13	16

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.493 (Fisher's exact test), Q value = 1

Table S578. Gene #62: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
PRSS27 MUTATED	1	1	0	0	1	0
PRSS27 WILD-TYPE	5	15	9	10	6	6

'SEMA5B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S579. Gene #63: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
SEMA5B MUTATED	4	2	0	1	0	0	1
SEMA5B WILD-TYPE	6	12	7	13	8	4	2

'SEMA5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.534 (Fisher's exact test), Q value = 1

Table S580. Gene #63: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
SEMA5B MUTATED	2	3	0	0	0	1	0
SEMA5B WILD-TYPE	10	8	5	10	6	8	2

'SEMA5B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S581. Gene #63: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
SEMA5B MUTATED	2	0	1	1
SEMA5B WILD-TYPE	5	7	5	7

'SEMA5B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.175 (Fisher's exact test), Q value = 1

Table S582. Gene #63: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
SEMA5B MUTATED	2	0	1	0	0	1	0	0
SEMA5B WILD-TYPE	3	6	4	3	3	0	3	2

'SEMA5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.461 (Fisher's exact test), Q value = 1

Table S583. Gene #63: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
SEMA5B MUTATED	3	1	0	2
SEMA5B WILD-TYPE	13	8	13	14

'SEMA5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.214 (Fisher's exact test), Q value = 1

Table S584. Gene #63: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SEMA5B MUTATED	3	0	1	2
SEMA5B WILD-TYPE	13	16	3	16

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.486 (Fisher's exact test), Q value = 1

Table S585. Gene #63: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
SEMA5B MUTATED	1	3	2
SEMA5B WILD-TYPE	20	14	15

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.298 (Fisher's exact test), Q value = 1

Table S586. Gene #63: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SEMA5B MUTATED	0	4	0	2	0
SEMA5B WILD-TYPE	13	14	8	12	2

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S587. Gene #63: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
SEMA5B MUTATED	2	2	0	2
SEMA5B WILD-TYPE	10	10	14	14

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S588. Gene #63: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
SEMA5B MUTATED	0	3	0	2	1	0
SEMA5B WILD-TYPE	6	13	9	8	6	6

'CD320 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.968 (Fisher's exact test), Q value = 1

Table S589. Gene #64: 'CD320 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
CD320 MUTATED	1	1	1	1	0	0	0
CD320 WILD-TYPE	9	13	6	13	8	4	3

'CD320 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S590. Gene #64: 'CD320 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
CD320 MUTATED	1	1	0	1	0	1	0
CD320 WILD-TYPE	11	10	5	9	6	8	2

'CD320 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S591. Gene #64: 'CD320 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
CD320 MUTATED	1	1	1	1
CD320 WILD-TYPE	15	8	12	15

'CD320 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.654 (Fisher's exact test), Q value = 1

Table S592. Gene #64: 'CD320 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CD320 MUTATED	1	1	1	1
CD320 WILD-TYPE	15	15	3	17

'CD320 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.367 (Fisher's exact test), Q value = 1

Table S593. Gene #64: 'CD320 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
CD320 MUTATED	3	1	0
CD320 WILD-TYPE	18	16	17

'CD320 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.225 (Fisher's exact test), Q value = 1

Table S594. Gene #64: 'CD320 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CD320 MUTATED	1	0	2	1	0
CD320 WILD-TYPE	12	18	6	13	2

'CD320 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 1

Table S595. Gene #64: 'CD320 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
CD320 MUTATED	1	0	3	0
CD320 WILD-TYPE	11	12	11	16

'CD320 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.227 (Fisher's exact test), Q value = 1

Table S596. Gene #64: 'CD320 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
CD320 MUTATED	1	0	2	1	0	0
CD320 WILD-TYPE	5	16	7	9	7	6

'TAF5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.967 (Fisher's exact test), Q value = 1

Table S597. Gene #65: 'TAF5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
TAF5 MUTATED	1	1	1	1	0	0	0
TAF5 WILD-TYPE	9	13	6	13	8	4	3

'TAF5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S598. Gene #65: 'TAF5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
TAF5 MUTATED	1	1	0	1	0	1	0
TAF5 WILD-TYPE	11	10	5	9	6	8	2

'TAF5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.31 (Fisher's exact test), Q value = 1

Table S599. Gene #65: 'TAF5 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
TAF5 MUTATED	2	1	0	0
TAF5 WILD-TYPE	5	6	6	8

'TAF5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.954 (Fisher's exact test), Q value = 1

Table S600. Gene #65: 'TAF5 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TAF5 MUTATED	1	1	0	0	1	0	0	0
TAF5 WILD-TYPE	4	5	5	3	2	1	3	2

'TAF5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S601. Gene #65: 'TAF5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
TAF5 MUTATED	1	1	1	1
TAF5 WILD-TYPE	15	8	12	15

'TAF5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S602. Gene #65: 'TAF5 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TAF5 MUTATED	2	1	0	1
TAF5 WILD-TYPE	14	15	4	17

'TAF5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0995 (Fisher's exact test), Q value = 1

Table S603. Gene #65: 'TAF5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
TAF5 MUTATED	0	3	1
TAF5 WILD-TYPE	21	14	16

'TAF5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 1

Table S604. Gene #65: 'TAF5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TAF5 MUTATED	0	4	0	0	0
TAF5 WILD-TYPE	13	14	8	14	2

'TAF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.469 (Fisher's exact test), Q value = 1

Table S605. Gene #65: 'TAF5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
TAF5 MUTATED	1	2	0	1
TAF5 WILD-TYPE	11	10	14	15

'TAF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.167 (Fisher's exact test), Q value = 1

Table S606. Gene #65: 'TAF5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
TAF5 MUTATED	0	4	0	0	0	0
TAF5 WILD-TYPE	6	12	9	10	7	6

'NEFH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S607. Gene #66: 'NEFH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
NEFH MUTATED	2	0	1	2	1	0	0
NEFH WILD-TYPE	8	14	6	12	7	4	3

'NEFH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.366 (Fisher's exact test), Q value = 1

Table S608. Gene #66: 'NEFH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
NEFH MUTATED	3	1	0	0	0	0	0
NEFH WILD-TYPE	9	10	5	10	6	9	2

'NEFH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0792 (Fisher's exact test), Q value = 1

Table S609. Gene #66: 'NEFH MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
NEFH MUTATED	3	0	0	0
NEFH WILD-TYPE	13	9	13	16

'NEFH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.051 (Fisher's exact test), Q value = 1

Table S610. Gene #66: 'NEFH MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NEFH MUTATED	2	0	1	0
NEFH WILD-TYPE	14	16	3	18

'NEFH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.535 (Fisher's exact test), Q value = 1

Table S611. Gene #66: 'NEFH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
NEFH MUTATED	2	2	0
NEFH WILD-TYPE	19	15	17

'NEFH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.211 (Fisher's exact test), Q value = 1

Table S612. Gene #66: 'NEFH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NEFH MUTATED	1	0	0	3	0
NEFH WILD-TYPE	12	18	8	11	2

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00318 (Fisher's exact test), Q value = 1

Table S613. Gene #66: 'NEFH MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
NEFH MUTATED	4	0	0	0
NEFH WILD-TYPE	8	12	14	16

Figure S33. Get High-res Image Gene #66: 'NEFH MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S614. Gene #66: 'NEFH MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
NEFH MUTATED	1	0	0	2	1	0
NEFH WILD-TYPE	5	16	9	8	6	6

'DMKN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0997 (Fisher's exact test), Q value = 1

Table S615. Gene #67: 'DMKN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
DMKN MUTATED	1	0	0	0	1	0	1
DMKN WILD-TYPE	9	14	7	14	7	4	2

'DMKN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S616. Gene #67: 'DMKN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
DMKN MUTATED	0	1	0	2	0	0	0
DMKN WILD-TYPE	12	10	5	8	6	9	2

'DMKN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S617. Gene #67: 'DMKN MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
DMKN MUTATED	1	1	1	0
DMKN WILD-TYPE	15	8	12	16

'DMKN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S618. Gene #67: 'DMKN MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
DMKN MUTATED	1	2	0	0
DMKN WILD-TYPE	15	14	4	18

'DMKN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0512 (Fisher's exact test), Q value = 1

Table S619. Gene #67: 'DMKN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
DMKN MUTATED	0	3	0
DMKN WILD-TYPE	21	14	17

'DMKN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.571 (Fisher's exact test), Q value = 1

Table S620. Gene #67: 'DMKN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
DMKN MUTATED	0	1	0	2	0
DMKN WILD-TYPE	13	17	8	12	2

'DMKN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.12 (Fisher's exact test), Q value = 1

Table S621. Gene #67: 'DMKN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
DMKN MUTATED	1	2	0	0
DMKN WILD-TYPE	11	10	14	16

'DMKN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.893 (Fisher's exact test), Q value = 1

Table S622. Gene #67: 'DMKN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
DMKN MUTATED	0	1	0	1	1	0
DMKN WILD-TYPE	6	15	9	9	6	6

'NPTX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.256 (Fisher's exact test), Q value = 1

Table S623. Gene #68: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
NPTX1 MUTATED	0	0	0	2	0	1	0
NPTX1 WILD-TYPE	10	14	7	12	8	3	3

'NPTX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.55 (Fisher's exact test), Q value = 1

Table S624. Gene #68: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
NPTX1 MUTATED	0	1	1	1	0	0	0
NPTX1 WILD-TYPE	12	10	4	9	6	9	2

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S625. Gene #68: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
NPTX1 MUTATED	1	0	1	1
NPTX1 WILD-TYPE	15	9	12	15

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S626. Gene #68: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NPTX1 MUTATED	1	0	0	2
NPTX1 WILD-TYPE	15	16	4	16

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 1

Table S627. Gene #68: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
NPTX1 MUTATED	0	1	2
NPTX1 WILD-TYPE	21	16	15

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S628. Gene #68: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NPTX1 MUTATED	0	1	1	1	0
NPTX1 WILD-TYPE	13	17	7	13	2

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S629. Gene #68: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
NPTX1 MUTATED	0	1	0	2
NPTX1 WILD-TYPE	12	11	14	14

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S630. Gene #68: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
NPTX1 MUTATED	0	1	0	1	0	1
NPTX1 WILD-TYPE	6	15	9	9	7	5

'NOTCH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0315 (Fisher's exact test), Q value = 1

Table S631. Gene #69: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
NOTCH2 MUTATED	3	0	0	0	1	0	1
NOTCH2 WILD-TYPE	7	14	7	14	7	4	2

Figure S34. Get High-res Image Gene #69: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'NOTCH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S632. Gene #69: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
NOTCH2 MUTATED	1	1	0	2	0	0	0
NOTCH2 WILD-TYPE	11	10	5	8	6	9	2

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S633. Gene #69: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
NOTCH2 MUTATED	2	1	1	0
NOTCH2 WILD-TYPE	14	8	12	16

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.119 (Fisher's exact test), Q value = 1

Table S634. Gene #69: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NOTCH2 MUTATED	1	2	1	0
NOTCH2 WILD-TYPE	15	14	3	18

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.014 (Fisher's exact test), Q value = 1

Table S635. Gene #69: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
NOTCH2 MUTATED	0	4	0
NOTCH2 WILD-TYPE	21	13	17

Figure S35. Get High-res Image Gene #69: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.319 (Fisher's exact test), Q value = 1

Table S636. Gene #69: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NOTCH2 MUTATED	0	1	0	3	0
NOTCH2 WILD-TYPE	13	17	8	11	2

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0287 (Fisher's exact test), Q value = 1

Table S637. Gene #69: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
NOTCH2 MUTATED	3	1	0	0
NOTCH2 WILD-TYPE	9	11	14	16

Figure S36. Get High-res Image Gene #69: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S638. Gene #69: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
NOTCH2 MUTATED	0	1	0	2	1	0
NOTCH2 WILD-TYPE	6	15	9	8	6	6

'RNF39 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.788 (Fisher's exact test), Q value = 1

Table S639. Gene #70: 'RNF39 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
RNF39 MUTATED	1	1	0	1	2	0	0
RNF39 WILD-TYPE	9	13	7	13	6	4	3

'RNF39 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.411 (Fisher's exact test), Q value = 1

Table S640. Gene #70: 'RNF39 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
RNF39 MUTATED	1	1	2	1	0	0	0
RNF39 WILD-TYPE	11	10	3	9	6	9	2

'RNF39 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0744 (Fisher's exact test), Q value = 1

Table S641. Gene #70: 'RNF39 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
RNF39 MUTATED	1	3	0	0
RNF39 WILD-TYPE	6	4	6	8

'RNF39 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S642. Gene #70: 'RNF39 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
RNF39 MUTATED	1	2	0	1	0	0	0	0
RNF39 WILD-TYPE	4	4	5	2	3	1	3	2

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 1

Table S643. Gene #70: 'RNF39 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
RNF39 MUTATED	1	1	3	0
RNF39 WILD-TYPE	15	8	10	16

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.263 (Fisher's exact test), Q value = 1

Table S644. Gene #70: 'RNF39 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RNF39 MUTATED	2	3	0	0
RNF39 WILD-TYPE	14	13	4	18

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.359 (Fisher's exact test), Q value = 1

Table S645. Gene #70: 'RNF39 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
RNF39 MUTATED	3	2	0
RNF39 WILD-TYPE	18	15	17

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S646. Gene #70: 'RNF39 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RNF39 MUTATED	2	1	0	2	0
RNF39 WILD-TYPE	11	17	8	12	2

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.385 (Fisher's exact test), Q value = 1

Table S647. Gene #70: 'RNF39 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
RNF39 MUTATED	2	1	2	0
RNF39 WILD-TYPE	10	11	12	16

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S648. Gene #70: 'RNF39 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
RNF39 MUTATED	0	1	2	2	0	0
RNF39 WILD-TYPE	6	15	7	8	7	6

'KBTBD13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.768 (Fisher's exact test), Q value = 1

Table S649. Gene #71: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
KBTBD13 MUTATED	3	3	0	2	1	0	0
KBTBD13 WILD-TYPE	7	11	7	12	7	4	3

'KBTBD13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S650. Gene #71: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
KBTBD13 MUTATED	3	3	0	0	2	1	0
KBTBD13 WILD-TYPE	9	8	5	10	4	8	2

'KBTBD13 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S651. Gene #71: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
KBTBD13 MUTATED	2	1	1	0
KBTBD13 WILD-TYPE	5	6	5	8

'KBTBD13 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S652. Gene #71: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
KBTBD13 MUTATED	1	0	1	1	1	0	0	0
KBTBD13 WILD-TYPE	4	6	4	2	2	1	3	2

'KBTBD13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.709 (Fisher's exact test), Q value = 1

Table S653. Gene #71: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
KBTBD13 MUTATED	4	1	1	3
KBTBD13 WILD-TYPE	12	8	12	13

'KBTBD13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S654. Gene #71: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KBTBD13 MUTATED	4	0	1	4
KBTBD13 WILD-TYPE	12	16	3	14

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.534 (Fisher's exact test), Q value = 1

Table S655. Gene #71: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
KBTBD13 MUTATED	2	4	3
KBTBD13 WILD-TYPE	19	13	14

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S656. Gene #71: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KBTBD13 MUTATED	0	4	2	3	0
KBTBD13 WILD-TYPE	13	14	6	11	2

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.661 (Fisher's exact test), Q value = 1

Table S657. Gene #71: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
KBTBD13 MUTATED	3	2	1	3
KBTBD13 WILD-TYPE	9	10	13	13

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.905 (Fisher's exact test), Q value = 1

Table S658. Gene #71: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
KBTBD13 MUTATED	0	4	1	2	1	1
KBTBD13 WILD-TYPE	6	12	8	8	6	5

'IER5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.259 (Fisher's exact test), Q value = 1

Table S659. Gene #72: 'IER5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
IER5 MUTATED	0	0	0	3	0	0	0
IER5 WILD-TYPE	10	14	7	11	8	4	3

'SCRT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.942 (Fisher's exact test), Q value = 1

Table S660. Gene #73: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
SCRT1 MUTATED	0	1	0	1	1	0	0
SCRT1 WILD-TYPE	10	13	7	13	7	4	3

'SCRT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S661. Gene #73: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
SCRT1 MUTATED	2	0	0	0	0	1	0
SCRT1 WILD-TYPE	10	11	5	10	6	8	2

'SCRT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S662. Gene #73: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
SCRT1 MUTATED	2	0	1	0
SCRT1 WILD-TYPE	14	9	12	16

'SCRT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S663. Gene #73: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SCRT1 MUTATED	2	0	0	1
SCRT1 WILD-TYPE	14	16	4	17

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.768 (Fisher's exact test), Q value = 1

Table S664. Gene #73: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
SCRT1 MUTATED	2	1	0
SCRT1 WILD-TYPE	19	16	17

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S665. Gene #73: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SCRT1 MUTATED	0	1	1	1	0
SCRT1 WILD-TYPE	13	17	7	13	2

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.369 (Fisher's exact test), Q value = 1

Table S666. Gene #73: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
SCRT1 MUTATED	1	0	2	0
SCRT1 WILD-TYPE	11	12	12	16

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S667. Gene #73: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
SCRT1 MUTATED	0	1	1	1	0	0
SCRT1 WILD-TYPE	6	15	8	9	7	6

'KNDC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.669 (Fisher's exact test), Q value = 1

Table S668. Gene #74: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
KNDC1 MUTATED	0	3	1	2	2	1	0
KNDC1 WILD-TYPE	10	11	6	12	6	3	3

'KNDC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0158 (Fisher's exact test), Q value = 1

Table S669. Gene #74: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
KNDC1 MUTATED	0	0	0	2	3	2	1
KNDC1 WILD-TYPE	12	11	5	8	3	7	1

Figure S37. Get High-res Image Gene #74: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'KNDC1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S670. Gene #74: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
KNDC1 MUTATED	1	0	0	2
KNDC1 WILD-TYPE	6	7	6	6

'KNDC1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.555 (Fisher's exact test), Q value = 1

Table S671. Gene #74: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
KNDC1 MUTATED	2	0	1	0	0	0	0	0
KNDC1 WILD-TYPE	3	6	4	3	3	1	3	2

'KNDC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.041 (Fisher's exact test), Q value = 1

Table S672. Gene #74: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
KNDC1 MUTATED	0	3	1	4
KNDC1 WILD-TYPE	16	6	12	12

Figure S38. Get High-res Image Gene #74: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'KNDC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.327 (Fisher's exact test), Q value = 1

Table S673. Gene #74: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KNDC1 MUTATED	1	2	0	5
KNDC1 WILD-TYPE	15	14	4	13

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S674. Gene #74: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
KNDC1 MUTATED	2	2	4
KNDC1 WILD-TYPE	19	15	13

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.365 (Fisher's exact test), Q value = 1

Table S675. Gene #74: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KNDC1 MUTATED	1	3	3	1	0
KNDC1 WILD-TYPE	12	15	5	13	2

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.362 (Fisher's exact test), Q value = 1

Table S676. Gene #74: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
KNDC1 MUTATED	0	2	2	4
KNDC1 WILD-TYPE	12	10	12	12

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S677. Gene #74: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
KNDC1 MUTATED	1	3	1	0	1	2
KNDC1 WILD-TYPE	5	13	8	10	6	4

'MAP1S MUTATION STATUS' versus 'CN_CNMF'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S678. Gene #75: 'MAP1S MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
MAP1S MUTATED	0	1	0	2	1	0	1
MAP1S WILD-TYPE	10	13	7	12	7	4	2

'MAP1S MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.364 (Fisher's exact test), Q value = 1

Table S679. Gene #75: 'MAP1S MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
MAP1S MUTATED	1	2	0	0	0	1	1
MAP1S WILD-TYPE	11	9	5	10	6	8	1

'MAP1S MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 1

Table S680. Gene #75: 'MAP1S MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
MAP1S MUTATED	2	0	0	2
MAP1S WILD-TYPE	5	7	6	6

'MAP1S MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S681. Gene #75: 'MAP1S MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
MAP1S MUTATED	2	0	2	0	0	0	0	0
MAP1S WILD-TYPE	3	6	3	3	3	1	3	2

'MAP1S MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S682. Gene #75: 'MAP1S MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
MAP1S MUTATED	1	1	0	3
MAP1S WILD-TYPE	15	8	13	13

'MAP1S MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S683. Gene #75: 'MAP1S MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MAP1S MUTATED	2	1	0	2
MAP1S WILD-TYPE	14	15	4	16

'MAP1S MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S684. Gene #75: 'MAP1S MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
MAP1S MUTATED	2	1	2
MAP1S WILD-TYPE	19	16	15

'MAP1S MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S685. Gene #75: 'MAP1S MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MAP1S MUTATED	2	2	0	1	0
MAP1S WILD-TYPE	11	16	8	13	2

'MAP1S MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S686. Gene #75: 'MAP1S MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
MAP1S MUTATED	1	1	1	2
MAP1S WILD-TYPE	11	11	13	14

'MAP1S MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S687. Gene #75: 'MAP1S MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
MAP1S MUTATED	1	2	1	0	1	0
MAP1S WILD-TYPE	5	14	8	10	6	6

'RGMB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.367 (Fisher's exact test), Q value = 1

Table S688. Gene #76: 'RGMB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
RGMB MUTATED	0	1	2	3	0	0	0
RGMB WILD-TYPE	10	13	5	11	8	4	3

'LRP11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.321 (Fisher's exact test), Q value = 1

Table S689. Gene #77: 'LRP11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
LRP11 MUTATED	0	2	1	0	2	0	0
LRP11 WILD-TYPE	10	12	6	14	6	4	3

'LRP11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.388 (Fisher's exact test), Q value = 1

Table S690. Gene #77: 'LRP11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
LRP11 MUTATED	1	0	0	3	0	1	0
LRP11 WILD-TYPE	11	11	5	7	6	8	2

'LRP11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.798 (Fisher's exact test), Q value = 1

Table S691. Gene #77: 'LRP11 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
LRP11 MUTATED	1	1	2	1
LRP11 WILD-TYPE	15	8	11	15

'LRP11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.666 (Fisher's exact test), Q value = 1

Table S692. Gene #77: 'LRP11 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
LRP11 MUTATED	1	3	0	1
LRP11 WILD-TYPE	15	13	4	17

'LRP11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S693. Gene #77: 'LRP11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
LRP11 MUTATED	2	2	1
LRP11 WILD-TYPE	19	15	16

'LRP11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S694. Gene #77: 'LRP11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
LRP11 MUTATED	1	2	0	2	0
LRP11 WILD-TYPE	12	16	8	12	2

'LRP11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.924 (Fisher's exact test), Q value = 1

Table S695. Gene #77: 'LRP11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
LRP11 MUTATED	1	1	2	1
LRP11 WILD-TYPE	11	11	12	15

'LRP11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.595 (Fisher's exact test), Q value = 1

Table S696. Gene #77: 'LRP11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
LRP11 MUTATED	1	2	0	2	0	0
LRP11 WILD-TYPE	5	14	9	8	7	6

'AR MUTATION STATUS' versus 'CN_CNMF'

P value = 0.308 (Fisher's exact test), Q value = 1

Table S697. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
AR MUTATED	0	0	0	2	1	1	0
AR WILD-TYPE	10	14	7	12	7	3	3

'AR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.282 (Fisher's exact test), Q value = 1

Table S698. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
AR MUTATED	2	0	1	0	0	0	0
AR WILD-TYPE	10	11	4	10	6	9	2

'AR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S699. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
AR MUTATED	1	1	0	1
AR WILD-TYPE	6	6	6	7

'AR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.954 (Fisher's exact test), Q value = 1

Table S700. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
AR MUTATED	1	1	0	0	1	0	0	0
AR WILD-TYPE	4	5	5	3	2	1	3	2

'AR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S701. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
AR MUTATED	2	0	1	0
AR WILD-TYPE	14	9	12	16

'AR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S702. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
AR MUTATED	2	1	0	0
AR WILD-TYPE	14	15	4	18

'AR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S703. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
AR MUTATED	2	1	0
AR WILD-TYPE	19	16	17

'AR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S704. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
AR MUTATED	1	1	0	1	0
AR WILD-TYPE	12	17	8	13	2

'AR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.192 (Fisher's exact test), Q value = 1

Table S705. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
AR MUTATED	2	0	1	0
AR WILD-TYPE	10	12	13	16

'AR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S706. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
AR MUTATED	0	1	1	1	0	0
AR WILD-TYPE	6	15	8	9	7	6

'VARS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S707. Gene #79: 'VARS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
VARS MUTATED	1	2	1	0	2	0	0
VARS WILD-TYPE	9	12	6	14	6	4	3

'VARS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.359 (Fisher's exact test), Q value = 1

Table S708. Gene #79: 'VARS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
VARS MUTATED	0	1	1	3	0	1	0
VARS WILD-TYPE	12	10	4	7	6	8	2

'VARS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 1

Table S709. Gene #79: 'VARS MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
VARS MUTATED	1	2	0	0
VARS WILD-TYPE	6	5	6	8

'VARS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S710. Gene #79: 'VARS MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
VARS MUTATED	0	1	0	0	1	0	0	1
VARS WILD-TYPE	5	5	5	3	2	1	3	1

'VARS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S711. Gene #79: 'VARS MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
VARS MUTATED	1	1	3	1
VARS WILD-TYPE	15	8	10	15

'VARS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0677 (Fisher's exact test), Q value = 1

Table S712. Gene #79: 'VARS MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
VARS MUTATED	0	4	1	1
VARS WILD-TYPE	16	12	3	17

'VARS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S713. Gene #79: 'VARS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
VARS MUTATED	2	2	2
VARS WILD-TYPE	19	15	15

'VARS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S714. Gene #79: 'VARS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
VARS MUTATED	2	2	0	2	0
VARS WILD-TYPE	11	16	8	12	2

'VARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S715. Gene #79: 'VARS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
VARS MUTATED	2	1	2	1
VARS WILD-TYPE	10	11	12	15

'VARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S716. Gene #79: 'VARS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
VARS MUTATED	1	2	1	1	1	0
VARS WILD-TYPE	5	14	8	9	6	6

'SEZ6L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.656 (Fisher's exact test), Q value = 1

Table S717. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
SEZ6L2 MUTATED	0	2	2	2	1	1	0
SEZ6L2 WILD-TYPE	10	12	5	12	7	3	3

'SEZ6L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.143 (Fisher's exact test), Q value = 1

Table S718. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
SEZ6L2 MUTATED	1	1	2	1	0	0	1
SEZ6L2 WILD-TYPE	11	10	3	9	6	9	1

'SEZ6L2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S719. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
SEZ6L2 MUTATED	0	1	1	1
SEZ6L2 WILD-TYPE	7	6	5	7

'SEZ6L2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.788 (Fisher's exact test), Q value = 1

Table S720. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
SEZ6L2 MUTATED	0	2	1	0	0	0	0	0
SEZ6L2 WILD-TYPE	5	4	4	3	3	1	3	2

'SEZ6L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.831 (Fisher's exact test), Q value = 1

Table S721. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
SEZ6L2 MUTATED	2	0	2	2
SEZ6L2 WILD-TYPE	14	9	11	14

'SEZ6L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S722. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SEZ6L2 MUTATED	2	2	0	2
SEZ6L2 WILD-TYPE	14	14	4	16

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.866 (Fisher's exact test), Q value = 1

Table S723. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
SEZ6L2 MUTATED	3	1	2
SEZ6L2 WILD-TYPE	18	16	15

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.628 (Fisher's exact test), Q value = 1

Table S724. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SEZ6L2 MUTATED	1	1	2	2	0
SEZ6L2 WILD-TYPE	12	17	6	12	2

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S725. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
SEZ6L2 MUTATED	1	1	2	2
SEZ6L2 WILD-TYPE	11	11	12	14

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.576 (Fisher's exact test), Q value = 1

Table S726. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
SEZ6L2 MUTATED	0	1	2	2	0	1
SEZ6L2 WILD-TYPE	6	15	7	8	7	5

'PABPC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S727. Gene #81: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
PABPC1 MUTATED	1	0	1	1	0	0	1
PABPC1 WILD-TYPE	9	14	6	13	8	4	2

'FANK1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S728. Gene #82: 'FANK1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
FANK1 MUTATED	1	1	0	1	0	0	0
FANK1 WILD-TYPE	9	13	7	13	8	4	3

'FANK1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0518 (Fisher's exact test), Q value = 1

Table S729. Gene #82: 'FANK1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
FANK1 MUTATED	0	2	0	0	0	0	1
FANK1 WILD-TYPE	12	9	5	10	6	9	1

'FANK1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.866 (Fisher's exact test), Q value = 1

Table S730. Gene #82: 'FANK1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
FANK1 MUTATED	1	1	0	1
FANK1 WILD-TYPE	15	8	13	15

'FANK1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 1

Table S731. Gene #82: 'FANK1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
FANK1 MUTATED	1	0	1	1
FANK1 WILD-TYPE	15	16	3	17

'FANK1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 1

Table S732. Gene #82: 'FANK1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
FANK1 MUTATED	0	2	1
FANK1 WILD-TYPE	21	15	16

'FANK1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.232 (Fisher's exact test), Q value = 1

Table S733. Gene #82: 'FANK1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
FANK1 MUTATED	0	0	1	2	0
FANK1 WILD-TYPE	13	18	7	12	2

'FANK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.28 (Fisher's exact test), Q value = 1

Table S734. Gene #82: 'FANK1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
FANK1 MUTATED	0	2	0	1
FANK1 WILD-TYPE	12	10	14	15

'FANK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0367 (Fisher's exact test), Q value = 1

Table S735. Gene #82: 'FANK1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
FANK1 MUTATED	0	0	0	0	2	1
FANK1 WILD-TYPE	6	16	9	10	5	5

Figure S39. Get High-res Image Gene #82: 'FANK1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NMU MUTATION STATUS' versus 'CN_CNMF'

P value = 0.332 (Fisher's exact test), Q value = 1

Table S736. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
NMU MUTATED	1	1	2	0	0	0	0
NMU WILD-TYPE	9	13	5	14	8	4	3

'NMU MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.841 (Fisher's exact test), Q value = 1

Table S737. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
NMU MUTATED	1	0	0	1	1	1	0
NMU WILD-TYPE	11	11	5	9	5	8	2

'NMU MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S738. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
NMU MUTATED	0	2	0	1
NMU WILD-TYPE	16	7	13	15

'NMU MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S739. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NMU MUTATED	0	2	0	1
NMU WILD-TYPE	16	14	4	17

'NMU MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S740. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
NMU MUTATED	1	2	1
NMU WILD-TYPE	20	15	16

'NMU MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S741. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NMU MUTATED	2	2	0	0	0
NMU WILD-TYPE	11	16	8	14	2

'NMU MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S742. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
NMU MUTATED	1	1	1	1
NMU WILD-TYPE	11	11	13	15

'NMU MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.16 (Fisher's exact test), Q value = 1

Table S743. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
NMU MUTATED	2	2	0	0	0	0
NMU WILD-TYPE	4	14	9	10	7	6

'ADAD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 1

Table S744. Gene #84: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
ADAD2 MUTATED	1	0	1	0	1	1	0
ADAD2 WILD-TYPE	9	14	6	14	7	3	3

'ADAD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.48 (Fisher's exact test), Q value = 1

Table S745. Gene #84: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
ADAD2 MUTATED	0	1	0	2	1	0	0
ADAD2 WILD-TYPE	12	10	5	8	5	9	2

'ADAD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.746 (Fisher's exact test), Q value = 1

Table S746. Gene #84: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
ADAD2 MUTATED	1	0	2	1
ADAD2 WILD-TYPE	15	9	11	15

'ADAD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S747. Gene #84: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ADAD2 MUTATED	0	2	1	1
ADAD2 WILD-TYPE	16	14	3	17

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0979 (Fisher's exact test), Q value = 1

Table S748. Gene #84: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
ADAD2 MUTATED	0	3	1
ADAD2 WILD-TYPE	21	14	16

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S749. Gene #84: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ADAD2 MUTATED	0	3	0	1	0
ADAD2 WILD-TYPE	13	15	8	13	2

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.469 (Fisher's exact test), Q value = 1

Table S750. Gene #84: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
ADAD2 MUTATED	1	2	0	1
ADAD2 WILD-TYPE	11	10	14	15

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S751. Gene #84: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
ADAD2 MUTATED	0	2	0	1	1	0
ADAD2 WILD-TYPE	6	14	9	9	6	6

'CLIC6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.228 (Fisher's exact test), Q value = 1

Table S752. Gene #85: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
CLIC6 MUTATED	2	0	1	1	0	0	1
CLIC6 WILD-TYPE	8	14	6	13	8	4	2

'CLIC6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S753. Gene #85: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
CLIC6 MUTATED	0	2	1	1	0	0	0
CLIC6 WILD-TYPE	12	9	4	9	6	9	2

'CLIC6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.685 (Fisher's exact test), Q value = 1

Table S754. Gene #85: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
CLIC6 MUTATED	2	1	0	1
CLIC6 WILD-TYPE	14	8	13	15

'CLIC6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S755. Gene #85: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CLIC6 MUTATED	2	1	1	0
CLIC6 WILD-TYPE	14	15	3	18

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 1

Table S756. Gene #85: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
CLIC6 MUTATED	1	3	0
CLIC6 WILD-TYPE	20	14	17

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S757. Gene #85: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CLIC6 MUTATED	0	1	1	2	0
CLIC6 WILD-TYPE	13	17	7	12	2

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0487 (Fisher's exact test), Q value = 1

Table S758. Gene #85: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
CLIC6 MUTATED	0	3	1	0
CLIC6 WILD-TYPE	12	9	13	16

Figure S40. Get High-res Image Gene #85: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.967 (Fisher's exact test), Q value = 1

Table S759. Gene #85: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
CLIC6 MUTATED	0	1	1	1	1	0
CLIC6 WILD-TYPE	6	15	8	9	6	6

'PCDHB13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.529 (Fisher's exact test), Q value = 1

Table S760. Gene #86: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
PCDHB13 MUTATED	1	1	1	0	1	1	0
PCDHB13 WILD-TYPE	9	13	6	14	7	3	3

'PCDHB13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0281 (Fisher's exact test), Q value = 1

Table S761. Gene #86: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
PCDHB13 MUTATED	0	0	2	2	0	0	0
PCDHB13 WILD-TYPE	12	11	3	8	6	9	2

Figure S41. Get High-res Image Gene #86: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'PCDHB13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S762. Gene #86: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
PCDHB13 MUTATED	0	1	2	1
PCDHB13 WILD-TYPE	16	8	11	15

'PCDHB13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.356 (Fisher's exact test), Q value = 1

Table S763. Gene #86: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PCDHB13 MUTATED	0	3	0	1
PCDHB13 WILD-TYPE	16	13	4	17

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.37 (Fisher's exact test), Q value = 1

Table S764. Gene #86: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
PCDHB13 MUTATED	3	0	1
PCDHB13 WILD-TYPE	18	17	16

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0596 (Fisher's exact test), Q value = 1

Table S765. Gene #86: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PCDHB13 MUTATED	3	0	1	0	0
PCDHB13 WILD-TYPE	10	18	7	14	2

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 1

Table S766. Gene #86: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
PCDHB13 MUTATED	0	0	3	1
PCDHB13 WILD-TYPE	12	12	11	15

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0957 (Fisher's exact test), Q value = 1

Table S767. Gene #86: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
PCDHB13 MUTATED	1	0	2	0	0	1
PCDHB13 WILD-TYPE	5	16	7	10	7	5

'PLEC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 1

Table S768. Gene #87: 'PLEC MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
PLEC MUTATED	1	5	1	4	2	0	0
PLEC WILD-TYPE	9	9	6	10	6	4	3

'PLEC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.202 (Fisher's exact test), Q value = 1

Table S769. Gene #87: 'PLEC MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
PLEC MUTATED	1	1	3	1	2	2	0
PLEC WILD-TYPE	11	10	2	9	4	7	2

'PLEC MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 1

Table S770. Gene #87: 'PLEC MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
PLEC MUTATED	0	3	0	2
PLEC WILD-TYPE	7	4	6	6

'PLEC MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0472 (Fisher's exact test), Q value = 1

Table S771. Gene #87: 'PLEC MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
PLEC MUTATED	0	4	0	0	0	0	1	0
PLEC WILD-TYPE	5	2	5	3	3	1	2	2

Figure S42. Get High-res Image Gene #87: 'PLEC MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

'PLEC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S772. Gene #87: 'PLEC MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
PLEC MUTATED	2	0	5	3
PLEC WILD-TYPE	14	9	8	13

'PLEC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S773. Gene #87: 'PLEC MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PLEC MUTATED	2	4	0	4
PLEC WILD-TYPE	14	12	4	14

'PLEC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S774. Gene #87: 'PLEC MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
PLEC MUTATED	5	3	2
PLEC WILD-TYPE	16	14	15

'PLEC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.632 (Fisher's exact test), Q value = 1

Table S775. Gene #87: 'PLEC MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PLEC MUTATED	4	2	2	2	0
PLEC WILD-TYPE	9	16	6	12	2

'PLEC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S776. Gene #87: 'PLEC MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
PLEC MUTATED	1	2	5	2
PLEC WILD-TYPE	11	10	9	14

'PLEC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0626 (Fisher's exact test), Q value = 1

Table S777. Gene #87: 'PLEC MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
PLEC MUTATED	0	2	5	2	0	1
PLEC WILD-TYPE	6	14	4	8	7	5

'AMDHD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.284 (Fisher's exact test), Q value = 1

Table S778. Gene #88: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
AMDHD1 MUTATED	2	1	1	2	4	0	0
AMDHD1 WILD-TYPE	8	13	6	12	4	4	3

'AMDHD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.67 (Fisher's exact test), Q value = 1

Table S779. Gene #88: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
AMDHD1 MUTATED	1	2	0	3	2	1	0
AMDHD1 WILD-TYPE	11	9	5	7	4	8	2

'AMDHD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S780. Gene #88: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
AMDHD1 MUTATED	1	1	0	1
AMDHD1 WILD-TYPE	6	6	6	7

'AMDHD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S781. Gene #88: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
AMDHD1 MUTATED	1	0	0	0	1	0	0	1
AMDHD1 WILD-TYPE	4	6	5	3	2	1	3	1

'AMDHD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S782. Gene #88: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
AMDHD1 MUTATED	3	2	3	1
AMDHD1 WILD-TYPE	13	7	10	15

'AMDHD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.136 (Fisher's exact test), Q value = 1

Table S783. Gene #88: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
AMDHD1 MUTATED	1	4	2	2
AMDHD1 WILD-TYPE	15	12	2	16

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.73 (Fisher's exact test), Q value = 1

Table S784. Gene #88: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
AMDHD1 MUTATED	3	4	2
AMDHD1 WILD-TYPE	18	13	15

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S785. Gene #88: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
AMDHD1 MUTATED	1	4	1	3	0
AMDHD1 WILD-TYPE	12	14	7	11	2

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.541 (Fisher's exact test), Q value = 1

Table S786. Gene #88: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
AMDHD1 MUTATED	2	3	3	1
AMDHD1 WILD-TYPE	10	9	11	15

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S787. Gene #88: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
AMDHD1 MUTATED	1	3	1	2	2	0
AMDHD1 WILD-TYPE	5	13	8	8	5	6

'DSPP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.12 (Fisher's exact test), Q value = 1

Table S788. Gene #89: 'DSPP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
DSPP MUTATED	4	4	0	1	0	0	0
DSPP WILD-TYPE	6	10	7	13	8	4	3

'DSPP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.159 (Fisher's exact test), Q value = 1

Table S789. Gene #89: 'DSPP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
DSPP MUTATED	1	3	2	0	0	3	0
DSPP WILD-TYPE	11	8	3	10	6	6	2

'DSPP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.23 (Fisher's exact test), Q value = 1

Table S790. Gene #89: 'DSPP MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
DSPP MUTATED	2	2	0	0
DSPP WILD-TYPE	5	5	6	8

'DSPP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.692 (Fisher's exact test), Q value = 1

Table S791. Gene #89: 'DSPP MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
DSPP MUTATED	1	1	0	1	0	0	0	1
DSPP WILD-TYPE	4	5	5	2	3	1	3	1

'DSPP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S792. Gene #89: 'DSPP MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
DSPP MUTATED	3	1	2	3
DSPP WILD-TYPE	13	8	11	13

'DSPP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S793. Gene #89: 'DSPP MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
DSPP MUTATED	4	1	1	3
DSPP WILD-TYPE	12	15	3	15

'DSPP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.729 (Fisher's exact test), Q value = 1

Table S794. Gene #89: 'DSPP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
DSPP MUTATED	3	4	2
DSPP WILD-TYPE	18	13	15

'DSPP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S795. Gene #89: 'DSPP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
DSPP MUTATED	1	4	1	2	1
DSPP WILD-TYPE	12	14	7	12	1

'DSPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.427 (Fisher's exact test), Q value = 1

Table S796. Gene #89: 'DSPP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
DSPP MUTATED	1	4	2	2
DSPP WILD-TYPE	11	8	12	14

'DSPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S797. Gene #89: 'DSPP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
DSPP MUTATED	0	3	2	1	3	0
DSPP WILD-TYPE	6	13	7	9	4	6

'TMEM189 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.783 (Fisher's exact test), Q value = 1

Table S798. Gene #90: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
TMEM189 MUTATED	1	0	0	1	1	0	0
TMEM189 WILD-TYPE	9	14	7	13	7	4	3

'CRIPAK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 1

Table S799. Gene #91: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
CRIPAK MUTATED	1	4	2	0	3	0	0
CRIPAK WILD-TYPE	9	10	5	14	5	4	3

'CRIPAK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.53 (Fisher's exact test), Q value = 1

Table S800. Gene #91: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
CRIPAK MUTATED	2	1	0	1	1	3	1
CRIPAK WILD-TYPE	10	10	5	9	5	6	1

'CRIPAK MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S801. Gene #91: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
CRIPAK MUTATED	0	1	1	2
CRIPAK WILD-TYPE	7	6	5	6

'CRIPAK MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.934 (Fisher's exact test), Q value = 1

Table S802. Gene #91: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CRIPAK MUTATED	1	2	1	0	0	0	0	0
CRIPAK WILD-TYPE	4	4	4	3	3	1	3	2

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S803. Gene #91: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
CRIPAK MUTATED	2	0	3	4
CRIPAK WILD-TYPE	14	9	10	12

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.69 (Fisher's exact test), Q value = 1

Table S804. Gene #91: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CRIPAK MUTATED	2	2	1	4
CRIPAK WILD-TYPE	14	14	3	14

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S805. Gene #91: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
CRIPAK MUTATED	5	1	3
CRIPAK WILD-TYPE	16	16	14

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.328 (Fisher's exact test), Q value = 1

Table S806. Gene #91: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CRIPAK MUTATED	1	4	3	1	0
CRIPAK WILD-TYPE	12	14	5	13	2

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.493 (Fisher's exact test), Q value = 1

Table S807. Gene #91: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
CRIPAK MUTATED	1	1	4	3
CRIPAK WILD-TYPE	11	11	10	13

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S808. Gene #91: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
CRIPAK MUTATED	1	4	3	1	0	0
CRIPAK WILD-TYPE	5	12	6	9	7	6

'PDCD6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S809. Gene #92: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
PDCD6 MUTATED	0	1	1	0	1	0	0
PDCD6 WILD-TYPE	10	13	6	14	7	4	3

'PDCD6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.643 (Fisher's exact test), Q value = 1

Table S810. Gene #92: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
PDCD6 MUTATED	1	0	0	0	1	1	0
PDCD6 WILD-TYPE	11	11	5	10	5	8	2

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S811. Gene #92: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
PDCD6 MUTATED	1	1	1
PDCD6 WILD-TYPE	20	16	16

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.639 (Fisher's exact test), Q value = 1

Table S812. Gene #92: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PDCD6 MUTATED	1	1	1	0	0
PDCD6 WILD-TYPE	12	17	7	14	2

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S813. Gene #92: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
PDCD6 MUTATED	1	0	1	1
PDCD6 WILD-TYPE	11	12	13	15

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.686 (Fisher's exact test), Q value = 1

Table S814. Gene #92: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
PDCD6 MUTATED	1	1	1	0	0	0
PDCD6 WILD-TYPE	5	15	8	10	7	6

'MAP7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.857 (Fisher's exact test), Q value = 1

Table S815. Gene #93: 'MAP7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
MAP7 MUTATED	0	1	0	2	0	0	0
MAP7 WILD-TYPE	10	13	7	12	8	4	3

'MAP7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.826 (Fisher's exact test), Q value = 1

Table S816. Gene #93: 'MAP7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
MAP7 MUTATED	1	1	0	0	1	0	0
MAP7 WILD-TYPE	11	10	5	10	5	9	2

'MAP7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S817. Gene #93: 'MAP7 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
MAP7 MUTATED	1	0	1	1
MAP7 WILD-TYPE	15	9	12	15

'MAP7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.813 (Fisher's exact test), Q value = 1

Table S818. Gene #93: 'MAP7 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MAP7 MUTATED	1	0	0	2
MAP7 WILD-TYPE	15	16	4	16

'MAP7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.498 (Fisher's exact test), Q value = 1

Table S819. Gene #93: 'MAP7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
MAP7 MUTATED	1	0	2
MAP7 WILD-TYPE	20	17	15

'MAP7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S820. Gene #93: 'MAP7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MAP7 MUTATED	0	1	1	1	0
MAP7 WILD-TYPE	13	17	7	13	2

'MAP7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S821. Gene #93: 'MAP7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
MAP7 MUTATED	1	0	0	2
MAP7 WILD-TYPE	11	12	14	14

'MAP7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S822. Gene #93: 'MAP7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
MAP7 MUTATED	0	1	0	1	0	1
MAP7 WILD-TYPE	6	15	9	9	7	5

'NOM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.639 (Fisher's exact test), Q value = 1

Table S823. Gene #94: 'NOM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
NOM1 MUTATED	2	2	1	0	1	0	0
NOM1 WILD-TYPE	8	12	6	14	7	4	3

'NOM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S824. Gene #94: 'NOM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
NOM1 MUTATED	1	2	0	1	1	0	0
NOM1 WILD-TYPE	11	9	5	9	5	9	2

'NOM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.647 (Fisher's exact test), Q value = 1

Table S825. Gene #94: 'NOM1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
NOM1 MUTATED	2	1	0	2
NOM1 WILD-TYPE	14	8	13	14

'NOM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S826. Gene #94: 'NOM1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NOM1 MUTATED	2	1	0	2
NOM1 WILD-TYPE	14	15	4	16

'NOM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S827. Gene #94: 'NOM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
NOM1 MUTATED	2	1	2
NOM1 WILD-TYPE	19	16	15

'NOM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.788 (Fisher's exact test), Q value = 1

Table S828. Gene #94: 'NOM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NOM1 MUTATED	2	1	1	1	0
NOM1 WILD-TYPE	11	17	7	13	2

'NOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S829. Gene #94: 'NOM1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
NOM1 MUTATED	1	1	1	2
NOM1 WILD-TYPE	11	11	13	14

'NOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.16 (Fisher's exact test), Q value = 1

Table S830. Gene #94: 'NOM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
NOM1 MUTATED	2	1	0	0	1	1
NOM1 WILD-TYPE	4	15	9	10	6	5

'SHOX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0435 (Fisher's exact test), Q value = 1

Table S831. Gene #95: 'SHOX2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
SHOX2 MUTATED	2	0	0	0	0	0	1
SHOX2 WILD-TYPE	8	14	7	14	8	4	2

Figure S43. Get High-res Image Gene #95: 'SHOX2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'HSD17B1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S832. Gene #96: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
HSD17B1 MUTATED	2	2	0	0	0	0	0
HSD17B1 WILD-TYPE	8	12	7	14	8	4	3

'HSD17B1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.479 (Fisher's exact test), Q value = 1

Table S833. Gene #96: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
HSD17B1 MUTATED	0	2	0	0	1	1	0
HSD17B1 WILD-TYPE	12	9	5	10	5	8	2

'HSD17B1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S834. Gene #96: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
HSD17B1 MUTATED	1	0	1	1
HSD17B1 WILD-TYPE	6	7	5	7

'HSD17B1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S835. Gene #96: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
HSD17B1 MUTATED	0	0	1	0	1	0	1	0
HSD17B1 WILD-TYPE	5	6	4	3	2	1	2	2

'HSD17B1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.905 (Fisher's exact test), Q value = 1

Table S836. Gene #96: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
HSD17B1 MUTATED	2	0	1	1
HSD17B1 WILD-TYPE	14	9	12	15

'HSD17B1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00782 (Fisher's exact test), Q value = 1

Table S837. Gene #96: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
HSD17B1 MUTATED	0	0	2	2
HSD17B1 WILD-TYPE	16	16	2	16

Figure S44. Get High-res Image Gene #96: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S838. Gene #96: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
HSD17B1 MUTATED	1	2	1
HSD17B1 WILD-TYPE	20	15	16

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S839. Gene #96: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
HSD17B1 MUTATED	1	1	0	2	0
HSD17B1 WILD-TYPE	12	17	8	12	2

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S840. Gene #96: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
HSD17B1 MUTATED	1	1	1	1
HSD17B1 WILD-TYPE	11	11	13	15

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.312 (Fisher's exact test), Q value = 1

Table S841. Gene #96: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
HSD17B1 MUTATED	0	1	1	0	2	0
HSD17B1 WILD-TYPE	6	15	8	10	5	6

'PRKAR1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S842. Gene #97: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
PRKAR1A MUTATED	1	1	0	2	2	0	0
PRKAR1A WILD-TYPE	9	13	7	12	6	4	3

'PRKAR1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.471 (Fisher's exact test), Q value = 1

Table S843. Gene #97: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
PRKAR1A MUTATED	1	1	2	1	1	0	0
PRKAR1A WILD-TYPE	11	10	3	9	5	9	2

'PRKAR1A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S844. Gene #97: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
PRKAR1A MUTATED	1	2	0	1
PRKAR1A WILD-TYPE	6	5	6	7

'PRKAR1A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.792 (Fisher's exact test), Q value = 1

Table S845. Gene #97: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
PRKAR1A MUTATED	1	2	0	0	1	0	0	0
PRKAR1A WILD-TYPE	4	4	5	3	2	1	3	2

'PRKAR1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.228 (Fisher's exact test), Q value = 1

Table S846. Gene #97: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
PRKAR1A MUTATED	2	1	3	0
PRKAR1A WILD-TYPE	14	8	10	16

'PRKAR1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.398 (Fisher's exact test), Q value = 1

Table S847. Gene #97: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PRKAR1A MUTATED	1	3	1	1
PRKAR1A WILD-TYPE	15	13	3	17

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.169 (Fisher's exact test), Q value = 1

Table S848. Gene #97: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
PRKAR1A MUTATED	4	2	0
PRKAR1A WILD-TYPE	17	15	17

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S849. Gene #97: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PRKAR1A MUTATED	3	1	1	1	0
PRKAR1A WILD-TYPE	10	17	7	13	2

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0883 (Fisher's exact test), Q value = 1

Table S850. Gene #97: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
PRKAR1A MUTATED	1	1	4	0
PRKAR1A WILD-TYPE	11	11	10	16

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.18 (Fisher's exact test), Q value = 1

Table S851. Gene #97: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
PRKAR1A MUTATED	1	1	3	0	1	0
PRKAR1A WILD-TYPE	5	15	6	10	6	6

'KRTAP5-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0636 (Fisher's exact test), Q value = 1

Table S852. Gene #98: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
KRTAP5-5 MUTATED	0	0	1	0	1	0	1
KRTAP5-5 WILD-TYPE	10	14	6	14	7	4	2

'DLEU7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S853. Gene #99: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
DLEU7 MUTATED	1	0	1	1	0	0	0
DLEU7 WILD-TYPE	9	14	6	13	8	4	3

'FEZ2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S854. Gene #100: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
FEZ2 MUTATED	0	2	0	1	0	0	0
FEZ2 WILD-TYPE	10	12	7	13	8	4	3

'FEZ2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0402 (Fisher's exact test), Q value = 1

Table S855. Gene #100: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
FEZ2 MUTATED	0	0	0	0	1	1	1
FEZ2 WILD-TYPE	12	11	5	10	5	8	1

Figure S45. Get High-res Image Gene #100: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'FEZ2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.24 (Fisher's exact test), Q value = 1

Table S856. Gene #100: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
FEZ2 MUTATED	0	1	0	2
FEZ2 WILD-TYPE	16	8	13	14

'FEZ2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.815 (Fisher's exact test), Q value = 1

Table S857. Gene #100: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
FEZ2 MUTATED	1	0	0	2
FEZ2 WILD-TYPE	15	16	4	16

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 1

Table S858. Gene #100: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
FEZ2 MUTATED	0	1	2
FEZ2 WILD-TYPE	21	16	15

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S859. Gene #100: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
FEZ2 MUTATED	0	1	1	1	0
FEZ2 WILD-TYPE	13	17	7	13	2

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S860. Gene #100: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
FEZ2 MUTATED	0	1	0	2
FEZ2 WILD-TYPE	12	11	14	14

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.497 (Fisher's exact test), Q value = 1

Table S861. Gene #100: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
FEZ2 MUTATED	0	1	0	0	1	1
FEZ2 WILD-TYPE	6	15	9	10	6	5

'RASIP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0634 (Fisher's exact test), Q value = 1

Table S862. Gene #101: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
RASIP1 MUTATED	0	0	2	3	0	0	1
RASIP1 WILD-TYPE	10	14	5	11	8	4	2

'RASIP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S863. Gene #101: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
RASIP1 MUTATED	1	0	1	2	1	0	1
RASIP1 WILD-TYPE	11	11	4	8	5	9	1

'RASIP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0028 (Fisher's exact test), Q value = 1

Table S864. Gene #101: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
RASIP1 MUTATED	2	4	0	0
RASIP1 WILD-TYPE	14	5	13	16

Figure S46. Get High-res Image Gene #101: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'RASIP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.189 (Fisher's exact test), Q value = 1

Table S865. Gene #101: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RASIP1 MUTATED	3	3	0	0
RASIP1 WILD-TYPE	13	13	4	18

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.117 (Fisher's exact test), Q value = 1

Table S866. Gene #101: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
RASIP1 MUTATED	2	4	0
RASIP1 WILD-TYPE	19	13	17

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S867. Gene #101: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RASIP1 MUTATED	1	2	0	3	0
RASIP1 WILD-TYPE	12	16	8	11	2

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0434 (Fisher's exact test), Q value = 1

Table S868. Gene #101: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
RASIP1 MUTATED	1	4	1	0
RASIP1 WILD-TYPE	11	8	13	16

Figure S47. Get High-res Image Gene #101: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.739 (Fisher's exact test), Q value = 1

Table S869. Gene #101: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
RASIP1 MUTATED	1	2	0	2	1	0
RASIP1 WILD-TYPE	5	14	9	8	6	6

'JMJD4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.498 (Fisher's exact test), Q value = 1

Table S870. Gene #102: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
JMJD4 MUTATED	0	0	1	2	0	0	0
JMJD4 WILD-TYPE	10	14	6	12	8	4	3

'COQ2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 1

Table S871. Gene #103: 'COQ2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
COQ2 MUTATED	0	0	1	1	2	0	1
COQ2 WILD-TYPE	10	14	6	13	6	4	2

'COQ2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.085 (Fisher's exact test), Q value = 1

Table S872. Gene #103: 'COQ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
COQ2 MUTATED	0	1	1	0	2	0	0
COQ2 WILD-TYPE	12	10	4	10	4	9	2

'COQ2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S873. Gene #103: 'COQ2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
COQ2 MUTATED	0	1	2	1
COQ2 WILD-TYPE	16	8	11	15

'COQ2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S874. Gene #103: 'COQ2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
COQ2 MUTATED	0	2	0	2
COQ2 WILD-TYPE	16	14	4	16

'COQ2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S875. Gene #103: 'COQ2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
COQ2 MUTATED	2	1	1
COQ2 WILD-TYPE	19	16	16

'COQ2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.669 (Fisher's exact test), Q value = 1

Table S876. Gene #103: 'COQ2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
COQ2 MUTATED	1	2	1	0	0
COQ2 WILD-TYPE	12	16	7	14	2

'COQ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S877. Gene #103: 'COQ2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
COQ2 MUTATED	0	1	2	1
COQ2 WILD-TYPE	12	11	12	15

'COQ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S878. Gene #103: 'COQ2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
COQ2 MUTATED	0	2	2	0	0	0
COQ2 WILD-TYPE	6	14	7	10	7	6

'UQCRFS1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.623 (Fisher's exact test), Q value = 1

Table S879. Gene #104: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
UQCRFS1 MUTATED	0	1	1	1	0	1	0
UQCRFS1 WILD-TYPE	10	13	6	13	8	3	3

'UQCRFS1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.452 (Fisher's exact test), Q value = 1

Table S880. Gene #104: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
UQCRFS1 MUTATED	2	0	1	2	0	0	0
UQCRFS1 WILD-TYPE	10	11	4	8	6	9	2

'UQCRFS1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S881. Gene #104: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
UQCRFS1 MUTATED	1	1	1	1
UQCRFS1 WILD-TYPE	15	8	12	15

'UQCRFS1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S882. Gene #104: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
UQCRFS1 MUTATED	1	2	0	1
UQCRFS1 WILD-TYPE	15	14	4	17

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S883. Gene #104: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
UQCRFS1 MUTATED	3	1	1
UQCRFS1 WILD-TYPE	18	16	16

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.203 (Fisher's exact test), Q value = 1

Table S884. Gene #104: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
UQCRFS1 MUTATED	3	0	1	1	0
UQCRFS1 WILD-TYPE	10	18	7	13	2

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S885. Gene #104: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
UQCRFS1 MUTATED	2	0	2	1
UQCRFS1 WILD-TYPE	10	12	12	15

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S886. Gene #104: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
UQCRFS1 MUTATED	2	0	1	1	0	1
UQCRFS1 WILD-TYPE	4	16	8	9	7	5

'C9ORF66 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S887. Gene #105: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
C9ORF66 MUTATED	1	1	2	0	1	0	0
C9ORF66 WILD-TYPE	9	13	5	14	7	4	3

'C9ORF66 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S888. Gene #105: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
C9ORF66 MUTATED	1	1	0	1	1	1	0
C9ORF66 WILD-TYPE	11	10	5	9	5	8	2

'C9ORF66 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.368 (Fisher's exact test), Q value = 1

Table S889. Gene #105: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
C9ORF66 MUTATED	2	2	0	1
C9ORF66 WILD-TYPE	14	7	13	15

'C9ORF66 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.514 (Fisher's exact test), Q value = 1

Table S890. Gene #105: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
C9ORF66 MUTATED	1	2	1	1
C9ORF66 WILD-TYPE	15	14	3	17

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S891. Gene #105: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
C9ORF66 MUTATED	2	2	1
C9ORF66 WILD-TYPE	19	15	16

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S892. Gene #105: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
C9ORF66 MUTATED	1	2	0	2	0
C9ORF66 WILD-TYPE	12	16	8	12	2

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S893. Gene #105: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
C9ORF66 MUTATED	1	1	2	1
C9ORF66 WILD-TYPE	11	11	12	15

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S894. Gene #105: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
C9ORF66 MUTATED	1	2	0	1	1	0
C9ORF66 WILD-TYPE	5	14	9	9	6	6

'POLRMT MUTATION STATUS' versus 'CN_CNMF'

P value = 0.517 (Fisher's exact test), Q value = 1

Table S895. Gene #106: 'POLRMT MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
POLRMT MUTATED	0	1	0	1	1	0	1
POLRMT WILD-TYPE	10	13	7	13	7	4	2

'POLRMT MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.084 (Fisher's exact test), Q value = 1

Table S896. Gene #106: 'POLRMT MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
POLRMT MUTATED	0	2	0	0	2	0	0
POLRMT WILD-TYPE	12	9	5	10	4	9	2

'POLRMT MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.108 (Fisher's exact test), Q value = 1

Table S897. Gene #106: 'POLRMT MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
POLRMT MUTATED	1	0	2	0
POLRMT WILD-TYPE	6	7	4	8

'POLRMT MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S898. Gene #106: 'POLRMT MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
POLRMT MUTATED	0	0	2	0	0	0	1	0
POLRMT WILD-TYPE	5	6	3	3	3	1	2	2

'POLRMT MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.369 (Fisher's exact test), Q value = 1

Table S899. Gene #106: 'POLRMT MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
POLRMT MUTATED	0	0	2	2
POLRMT WILD-TYPE	16	9	11	14

'POLRMT MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0581 (Fisher's exact test), Q value = 1

Table S900. Gene #106: 'POLRMT MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
POLRMT MUTATED	0	0	0	4
POLRMT WILD-TYPE	16	16	4	14

'POLRMT MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.183 (Fisher's exact test), Q value = 1

Table S901. Gene #106: 'POLRMT MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
POLRMT MUTATED	1	0	3
POLRMT WILD-TYPE	20	17	14

'POLRMT MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.262 (Fisher's exact test), Q value = 1

Table S902. Gene #106: 'POLRMT MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
POLRMT MUTATED	0	3	1	0	0
POLRMT WILD-TYPE	13	15	7	14	2

'POLRMT MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 1

Table S903. Gene #106: 'POLRMT MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
POLRMT MUTATED	0	0	1	3
POLRMT WILD-TYPE	12	12	13	13

'POLRMT MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.55 (Fisher's exact test), Q value = 1

Table S904. Gene #106: 'POLRMT MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
POLRMT MUTATED	0	3	1	0	0	0
POLRMT WILD-TYPE	6	13	8	10	7	6

'ADAMTS7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0101 (Fisher's exact test), Q value = 1

Table S905. Gene #107: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
ADAMTS7 MUTATED	0	2	0	0	0	0	2
ADAMTS7 WILD-TYPE	10	12	7	14	8	4	1

Figure S48. Get High-res Image Gene #107: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'ADAMTS7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.722 (Fisher's exact test), Q value = 1

Table S906. Gene #107: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
ADAMTS7 MUTATED	0	2	0	1	0	1	0
ADAMTS7 WILD-TYPE	12	9	5	9	6	8	2

'ADAMTS7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0276 (Fisher's exact test), Q value = 1

Table S907. Gene #107: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
ADAMTS7 MUTATED	3	0	0	0
ADAMTS7 WILD-TYPE	4	7	6	8

Figure S49. Get High-res Image Gene #107: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

'ADAMTS7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S908. Gene #107: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ADAMTS7 MUTATED	0	0	2	0	1	0	0	0
ADAMTS7 WILD-TYPE	5	6	3	3	2	1	3	2

'ADAMTS7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.131 (Fisher's exact test), Q value = 1

Table S909. Gene #107: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
ADAMTS7 MUTATED	0	1	0	3
ADAMTS7 WILD-TYPE	16	8	13	13

'ADAMTS7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S910. Gene #107: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ADAMTS7 MUTATED	0	1	0	3
ADAMTS7 WILD-TYPE	16	15	4	15

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.101 (Fisher's exact test), Q value = 1

Table S911. Gene #107: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
ADAMTS7 MUTATED	0	1	3
ADAMTS7 WILD-TYPE	21	16	14

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.263 (Fisher's exact test), Q value = 1

Table S912. Gene #107: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ADAMTS7 MUTATED	0	3	1	0	0
ADAMTS7 WILD-TYPE	13	15	7	14	2

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 1

Table S913. Gene #107: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
ADAMTS7 MUTATED	0	1	0	3
ADAMTS7 WILD-TYPE	12	11	14	13

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S914. Gene #107: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
ADAMTS7 MUTATED	0	3	0	0	0	1
ADAMTS7 WILD-TYPE	6	13	9	10	7	5

'BTNL9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0566 (Fisher's exact test), Q value = 1

Table S915. Gene #108: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
BTNL9 MUTATED	1	0	0	0	2	0	1
BTNL9 WILD-TYPE	9	14	7	14	6	4	2

'BTNL9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.18 (Fisher's exact test), Q value = 1

Table S916. Gene #108: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
BTNL9 MUTATED	0	0	1	2	0	0	0
BTNL9 WILD-TYPE	12	11	4	8	6	9	2

'BTNL9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.153 (Fisher's exact test), Q value = 1

Table S917. Gene #108: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
BTNL9 MUTATED	0	1	2	0
BTNL9 WILD-TYPE	16	8	11	16

'BTNL9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0965 (Fisher's exact test), Q value = 1

Table S918. Gene #108: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
BTNL9 MUTATED	0	3	0	0
BTNL9 WILD-TYPE	16	13	4	18

'BTNL9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.494 (Fisher's exact test), Q value = 1

Table S919. Gene #108: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
BTNL9 MUTATED	1	2	0
BTNL9 WILD-TYPE	20	15	17

'BTNL9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S920. Gene #108: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
BTNL9 MUTATED	1	1	0	1	0
BTNL9 WILD-TYPE	12	17	8	13	2

'BTNL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.69 (Fisher's exact test), Q value = 1

Table S921. Gene #108: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
BTNL9 MUTATED	1	1	1	0
BTNL9 WILD-TYPE	11	11	13	16

'BTNL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S922. Gene #108: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
BTNL9 MUTATED	0	1	1	1	0	0
BTNL9 WILD-TYPE	6	15	8	9	7	6

'NF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.336 (Fisher's exact test), Q value = 1

Table S923. Gene #109: 'NF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
NF1 MUTATED	2	1	0	1	3	0	0
NF1 WILD-TYPE	8	13	7	13	5	4	3

'NF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.828 (Fisher's exact test), Q value = 1

Table S924. Gene #109: 'NF1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
NF1 MUTATED	2	2	0	2	1	0	0
NF1 WILD-TYPE	10	9	5	8	5	9	2

'NF1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S925. Gene #109: 'NF1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	7	7	6	8
NF1 MUTATED	1	2	0	1
NF1 WILD-TYPE	6	5	6	7

'NF1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.392 (Fisher's exact test), Q value = 1

Table S926. Gene #109: 'NF1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
NF1 MUTATED	1	0	0	1	1	0	0	1
NF1 WILD-TYPE	4	6	5	2	2	1	3	1

'NF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S927. Gene #109: 'NF1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
NF1 MUTATED	4	0	2	1
NF1 WILD-TYPE	12	9	11	15

'NF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.19 (Fisher's exact test), Q value = 1

Table S928. Gene #109: 'NF1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NF1 MUTATED	2	2	2	1
NF1 WILD-TYPE	14	14	2	17

'NF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S929. Gene #109: 'NF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
NF1 MUTATED	2	3	2
NF1 WILD-TYPE	19	14	15

'NF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S930. Gene #109: 'NF1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NF1 MUTATED	1	2	1	3	0
NF1 WILD-TYPE	12	16	7	11	2

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0495 (Fisher's exact test), Q value = 1

Table S931. Gene #109: 'NF1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
NF1 MUTATED	4	2	0	1
NF1 WILD-TYPE	8	10	14	15

Figure S50. Get High-res Image Gene #109: 'NF1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S932. Gene #109: 'NF1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
NF1 MUTATED	1	1	0	2	2	1
NF1 WILD-TYPE	5	15	9	8	5	5

'ZNF814 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.943 (Fisher's exact test), Q value = 1

Table S933. Gene #110: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
ZNF814 MUTATED	0	1	0	1	1	0	0
ZNF814 WILD-TYPE	10	13	7	13	7	4	3

'RNF135 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.717 (Fisher's exact test), Q value = 1

Table S934. Gene #111: 'RNF135 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
RNF135 MUTATED	1	1	1	0	0	0	0
RNF135 WILD-TYPE	9	13	6	14	8	4	3

'CSGALNACT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.856 (Fisher's exact test), Q value = 1

Table S935. Gene #112: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
CSGALNACT2 MUTATED	0	2	0	1	0	0	0
CSGALNACT2 WILD-TYPE	10	12	7	13	8	4	3

'CSGALNACT2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.221 (Fisher's exact test), Q value = 1

Table S936. Gene #112: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
CSGALNACT2 MUTATED	0	0	1	0	1	1	0
CSGALNACT2 WILD-TYPE	12	11	4	10	5	8	2

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S937. Gene #112: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
CSGALNACT2 MUTATED	1	0	0	2
CSGALNACT2 WILD-TYPE	15	9	13	14

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S938. Gene #112: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CSGALNACT2 MUTATED	1	0	0	2
CSGALNACT2 WILD-TYPE	15	16	4	16

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 1

Table S939. Gene #112: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
CSGALNACT2 MUTATED	0	1	2
CSGALNACT2 WILD-TYPE	21	16	15

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S940. Gene #112: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CSGALNACT2 MUTATED	0	2	0	1	0
CSGALNACT2 WILD-TYPE	13	16	8	13	2

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.482 (Fisher's exact test), Q value = 1

Table S941. Gene #112: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
CSGALNACT2 MUTATED	0	1	0	2
CSGALNACT2 WILD-TYPE	12	11	14	14

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.942 (Fisher's exact test), Q value = 1

Table S942. Gene #112: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
CSGALNACT2 MUTATED	0	2	0	1	0	0
CSGALNACT2 WILD-TYPE	6	14	9	9	7	6

'SPIRE2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.942 (Fisher's exact test), Q value = 1

Table S943. Gene #113: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
SPIRE2 MUTATED	0	1	0	1	1	0	0
SPIRE2 WILD-TYPE	10	13	7	13	7	4	3

'SPIRE2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.131 (Fisher's exact test), Q value = 1

Table S944. Gene #113: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
SPIRE2 MUTATED	1	0	0	0	2	0	0
SPIRE2 WILD-TYPE	11	11	5	10	4	9	2

'SPIRE2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S945. Gene #113: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
SPIRE2 MUTATED	1	0	1	1
SPIRE2 WILD-TYPE	15	9	12	15

'SPIRE2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S946. Gene #113: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SPIRE2 MUTATED	1	0	0	2
SPIRE2 WILD-TYPE	15	16	4	16

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.768 (Fisher's exact test), Q value = 1

Table S947. Gene #113: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
SPIRE2 MUTATED	2	0	1
SPIRE2 WILD-TYPE	19	17	16

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S948. Gene #113: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SPIRE2 MUTATED	0	1	1	1	0
SPIRE2 WILD-TYPE	13	17	7	13	2

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S949. Gene #113: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
SPIRE2 MUTATED	0	0	2	1
SPIRE2 WILD-TYPE	12	12	12	15

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S950. Gene #113: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
SPIRE2 MUTATED	0	1	1	1	0	0
SPIRE2 WILD-TYPE	6	15	8	9	7	6

'CYP4A22 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.152 (Fisher's exact test), Q value = 1

Table S951. Gene #114: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
CYP4A22 MUTATED	1	0	1	0	1	0	1
CYP4A22 WILD-TYPE	9	14	6	14	7	4	2

'CYP4A22 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S952. Gene #114: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
CYP4A22 MUTATED	1	1	0	2	0	0	0
CYP4A22 WILD-TYPE	11	10	5	8	6	9	2

'CYP4A22 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 1

Table S953. Gene #114: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
CYP4A22 MUTATED	1	2	1	0
CYP4A22 WILD-TYPE	15	7	12	16

'CYP4A22 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S954. Gene #114: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CYP4A22 MUTATED	2	2	0	0
CYP4A22 WILD-TYPE	14	14	4	18

'CYP4A22 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S955. Gene #114: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
CYP4A22 MUTATED	1	3	0
CYP4A22 WILD-TYPE	20	14	17

'CYP4A22 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S956. Gene #114: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CYP4A22 MUTATED	0	2	0	1	1
CYP4A22 WILD-TYPE	13	16	8	13	1

'CYP4A22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0481 (Fisher's exact test), Q value = 1

Table S957. Gene #114: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
CYP4A22 MUTATED	0	3	1	0
CYP4A22 WILD-TYPE	12	9	13	16

Figure S51. Get High-res Image Gene #114: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'CYP4A22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S958. Gene #114: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
CYP4A22 MUTATED	0	2	0	1	1	0
CYP4A22 WILD-TYPE	6	14	9	9	6	6

'HLA-A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.718 (Fisher's exact test), Q value = 1

Table S959. Gene #115: 'HLA-A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
HLA-A MUTATED	1	0	1	1	0	0	0
HLA-A WILD-TYPE	9	14	6	13	8	4	3

'HLA-A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.95 (Fisher's exact test), Q value = 1

Table S960. Gene #115: 'HLA-A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
HLA-A MUTATED	1	1	0	0	0	1	0
HLA-A WILD-TYPE	11	10	5	10	6	8	2

'HLA-A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.866 (Fisher's exact test), Q value = 1

Table S961. Gene #115: 'HLA-A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
HLA-A MUTATED	1	1	0	1
HLA-A WILD-TYPE	15	8	13	15

'HLA-A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.196 (Fisher's exact test), Q value = 1

Table S962. Gene #115: 'HLA-A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
HLA-A MUTATED	1	1	1	0
HLA-A WILD-TYPE	15	15	3	18

'HLA-A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.768 (Fisher's exact test), Q value = 1

Table S963. Gene #115: 'HLA-A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
HLA-A MUTATED	2	0	1
HLA-A WILD-TYPE	19	17	16

'HLA-A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S964. Gene #115: 'HLA-A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
HLA-A MUTATED	1	0	1	1	0
HLA-A WILD-TYPE	12	18	7	13	2

'HLA-A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S965. Gene #115: 'HLA-A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
HLA-A MUTATED	1	0	1	1
HLA-A WILD-TYPE	11	12	13	15

'HLA-A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.347 (Fisher's exact test), Q value = 1

Table S966. Gene #115: 'HLA-A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
HLA-A MUTATED	0	0	1	1	0	1
HLA-A WILD-TYPE	6	16	8	9	7	5

'GLI3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 1

Table S967. Gene #116: 'GLI3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	10	14	7	14	8	4	3
GLI3 MUTATED	0	0	0	4	1	0	0
GLI3 WILD-TYPE	10	14	7	10	7	4	3

'GLI3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.623 (Fisher's exact test), Q value = 1

Table S968. Gene #116: 'GLI3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7
ALL	12	11	5	10	6	9	2
GLI3 MUTATED	1	1	1	0	1	0	0
GLI3 WILD-TYPE	11	10	4	10	5	9	2

'GLI3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.907 (Fisher's exact test), Q value = 1

Table S969. Gene #116: 'GLI3 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	9	13	16
GLI3 MUTATED	2	0	1	1
GLI3 WILD-TYPE	14	9	12	15

'GLI3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S970. Gene #116: 'GLI3 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
GLI3 MUTATED	2	1	0	1
GLI3 WILD-TYPE	14	15	4	17

'GLI3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.37 (Fisher's exact test), Q value = 1

Table S971. Gene #116: 'GLI3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	17	17
GLI3 MUTATED	3	1	0
GLI3 WILD-TYPE	18	16	17

'GLI3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.414 (Fisher's exact test), Q value = 1

Table S972. Gene #116: 'GLI3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
GLI3 MUTATED	1	0	1	2	0
GLI3 WILD-TYPE	12	18	7	12	2

'GLI3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S973. Gene #116: 'GLI3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	12	12	14	16
GLI3 MUTATED	1	1	2	0
GLI3 WILD-TYPE	11	11	12	16

'GLI3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.138 (Fisher's exact test), Q value = 1

Table S974. Gene #116: 'GLI3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	6	16	9	10	7	6
GLI3 MUTATED	0	0	2	2	0	0
GLI3 WILD-TYPE	6	16	7	8	7	6

Methods & Data

Input

Mutation data file = sample_sig_gene_table.txt from Mutsig_2CV pipeline
Processed Mutation data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/ACC-TP/22573896/transformed.cor.cli.txt
Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/ACC-TP/22541000/ACC-TP.transferedmergedcluster.txt
Number of patients = 62
Number of significantly mutated genes = 116
Number of Molecular subtypes = 10
Exclude genes that fewer than K tumors have mutations, K = 3

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

Download Results

In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.

References

[1] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)

[2] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)

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