Clinical Features Time to Death YEARS_TO_BIRTH PATHOLOGIC_STAGE PATHOLOGY_T_STAGE PATHOLOGY_N_STAGE PATHOLOGY_M_STAGE GENDER RADIATION_THERAPY KARNOFSKY_PERFORMANCE_SCORE NUMBER_PACK_YEARS_SMOKED NUMBER_OF_LYMPH_NODES RACE ETHNICITY nMutated (%) nWild-Type logrank test_P logrank test_Q Wilcoxon-test_P Wilcoxon-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Wilcoxon-test_P Wilcoxon-test_Q Wilcoxon-test_P Wilcoxon-test_Q Wilcoxon-test_P Wilcoxon-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q TP53 196 (50%) 199 0.92653 1 0.50506 1 0.11037 0.937 0.5783 1 0.01639 0.797 0.53082 1 1 1 0.25223 1 0.29824 1 0.68031 1 0.10175 0.936 0.0015 0.614 1 1 RB1 70 (18%) 325 0.16539 1 0.089164 0.917 0.81138 1 0.44322 1 0.064939 0.9 0.63885 1 0.45156 1 0.54806 1 0.076678 0.907 0.074384 0.9 0.2901 1 0.45342 1 1 1 ELF3 46 (12%) 349 0.48553 1 0.0039871 0.797 0.95357 1 0.41465 1 0.98716 1 1 1 0.28345 1 1 1 0.71767 1 0.82146 1 0.92456 1 1 1 0.6029 1 TSC1 33 (8%) 362 0.4644 1 0.2812 1 0.64967 1 0.3214 1 0.67414 1 0.25892 1 1 1 0.39012 1 0.54211 1 0.2593 1 0.48686 1 0.80142 1 0.50199 1 PIK3CA 86 (22%) 309 0.52361 1 0.62893 1 0.64553 1 0.20598 1 0.24313 1 0.4625 1 1 1 0.26857 1 0.49498 1 0.18321 1 0.017677 0.797 0.19597 1 0.67901 1 RHOB 26 (7%) 369 0.83797 1 0.0611 0.9 0.70979 1 1 1 0.25719 1 0.55946 1 1 1 1 1 0.321 1 0.45134 1 0.77212 1 0.28855 1 1 1 KDM6A 103 (26%) 292 0.50847 1 0.71014 1 0.45908 1 0.70695 1 0.24818 1 0.74406 1 0.8967 1 0.30218 1 0.35324 1 0.1481 1 0.025053 0.797 0.97101 1 0.68568 1 CDKN2A 26 (7%) 369 0.71474 1 0.73482 1 0.37399 1 0.71294 1 1 1 0.50284 1 0.64273 1 1 1 0.86084 1 0.14324 1 0.54546 1 0.91284 1 1 1 ARID1A 97 (25%) 298 0.43543 1 0.38842 1 0.59474 1 0.56306 1 0.17207 1 0.73274 1 0.22903 1 0.42632 1 0.33395 1 0.35107 1 0.7001 1 0.00175 0.614 0.43171 1 STAG2 56 (14%) 339 0.2016 1 0.37597 1 0.10354 0.936 0.39068 1 0.30337 1 0.02292 0.797 0.51047 1 0.50291 1 0.20908 1 0.22541 1 0.16713 1 0.04817 0.852 0.60793 1 ZFP36L1 25 (6%) 370 0.29633 1 0.17764 1 0.1339 1 0.47992 1 0.24828 1 0.039285 0.797 1 1 0.35751 1 0.19421 1 0.81498 1 0.0088562 0.797 1 1 1 1 CDKN1A 35 (9%) 360 0.55358 1 0.95162 1 0.75102 1 0.19295 1 0.56693 1 1 1 0.31101 1 0.68756 1 0.0094132 0.797 0.68881 1 0.47728 1 0.02469 0.797 0.52567 1 EP300 61 (15%) 334 0.073116 0.9 0.2506 1 0.87692 1 0.4444 1 0.25905 1 0.69399 1 0.87473 1 0.22124 1 0.86627 1 0.28809 1 0.65858 1 0.18856 1 1 1 MLL2 114 (29%) 281 0.39032 1 0.089357 0.917 0.51087 1 0.92372 1 0.16502 1 0.30647 1 0.79996 1 1 1 0.755 1 0.58378 1 0.068621 0.9 0.34873 1 1 1 FGFR3 56 (14%) 339 0.16043 1 0.10124 0.936 0.01966 0.797 0.00287 0.756 0.096549 0.927 0.24776 1 0.032874 0.797 0.19639 1 0.051377 0.852 0.1228 0.958 0.54074 1 0.02454 0.797 0.60664 1 ERCC2 38 (10%) 357 0.088358 0.917 0.020092 0.797 0.50626 1 0.94558 1 1 1 1 1 0.56234 1 0.23748 1 0.019203 0.797 0.22501 1 0.3924 1 0.72563 1 0.17495 1 CREBBP 48 (12%) 347 0.47746 1 0.89129 1 0.95559 1 0.38505 1 1 1 0.66307 1 0.15861 1 0.49052 1 0.97366 1 0.83043 1 0.47873 1 1 1 0.60395 1 HRAS 17 (4%) 378 0.35158 1 0.32377 1 0.38635 1 0.10802 0.936 0.67625 1 0.43968 1 0.15819 1 0.57268 1 0.3523 1 0.42332 1 0.87257 1 0.0444 0.85 1 1 FOXA1 14 (4%) 381 0.61658 1 0.839 1 0.12385 0.959 0.36844 1 0.090949 0.917 0.080231 0.915 0.76237 1 0.54724 1 0.071535 0.9 0.030495 0.797 0.02052 0.797 0.69761 1 1 1 KRAS 13 (3%) 382 0.00083268 0.614 0.48937 1 0.41715 1 0.34472 1 0.01232 0.797 1 1 0.19787 1 0.49199 1 0.54623 1 0.11772 0.947 0.31992 1 0.29398 1 1 1 RHOA 18 (5%) 377 0.50243 1 0.45687 1 0.1386 1 0.47864 1 0.43737 1 0.064348 0.9 0.42212 1 0.6127 1 NA NA 0.0056228 0.797 0.8055 1 0.88653 1 0.28892 1 KIAA1267 24 (6%) 371 0.17606 1 0.12963 0.989 0.67124 1 0.47931 1 0.90803 1 0.55946 1 0.34559 1 0.35751 1 0.96599 1 0.33635 1 0.82019 1 0.33268 1 0.39662 1 MLL 44 (11%) 351 0.87932 1 0.013183 0.797 0.54531 1 0.5037 1 0.83032 1 0.6038 1 0.46711 1 0.71128 1 0.23217 1 0.66897 1 0.27706 1 0.83831 1 0.60589 1 FAT1 50 (13%) 345 0.52697 1 0.020582 0.797 0.1933 1 0.65372 1 0.20211 1 0.32443 1 0.039393 0.797 0.73313 1 0.11521 0.941 0.047811 0.852 0.024298 0.797 0.75955 1 0.29496 1 KLF5 23 (6%) 372 0.51051 1 0.6063 1 0.93311 1 0.1677 1 0.69026 1 1 1 0.32906 1 0.31594 1 0.093342 0.919 0.33889 1 0.77067 1 0.17359 1 1 1 PTEN 14 (4%) 381 0.58665 1 0.67654 1 0.89864 1 0.2015 1 0.55492 1 1 1 0.53376 1 1 1 0.90993 1 0.34524 1 0.60451 1 1 1 1 1 C3ORF70 17 (4%) 378 0.075683 0.906 0.07767 0.909 0.40232 1 0.2277 1 0.31607 1 0.43968 1 1 1 1 1 0.321 1 0.5525 1 0.014733 0.797 0.37076 1 1 1 PSIP1 20 (5%) 375 0.63168 1 0.12223 0.958 0.26962 1 0.11517 0.941 0.26251 1 0.53193 1 0.30702 1 0.25308 1 0.60343 1 0.22168 1 0.19268 1 0.19796 1 1 1 MLL3 74 (19%) 321 0.53917 1 0.86725 1 0.46359 1 0.33686 1 0.94983 1 0.25499 1 0.039205 0.797 0.77717 1 0.12958 0.989 0.42692 1 0.80074 1 0.46284 1 0.3607 1 ASXL2 36 (9%) 359 0.58724 1 0.5787 1 0.7139 1 0.64233 1 0.31892 1 1 1 1 1 0.39467 1 0.63309 1 0.62999 1 0.43488 1 0.70323 1 1 1 ZBTB7B 11 (3%) 384 0.14913 1 0.37966 1 0.81273 1 0.74632 1 0.81631 1 1 1 0.48481 1 1 1 0.37982 1 0.64038 1 0.135 1 0.0282 0.797 1 1 RXRA 24 (6%) 371 0.95365 1 0.10481 0.936 0.43834 1 0.39986 1 0.75266 1 0.53193 1 0.80985 1 1 1 0.15017 1 0.50061 1 0.5137 1 0.25668 1 0.38217 1 FBXW7 30 (8%) 365 0.32286 1 0.087955 0.917 0.31501 1 0.34791 1 0.24356 1 0.32443 1 0.19161 1 0.65603 1 0.72532 1 0.95188 1 0.27522 1 0.63996 1 1 1 RBM10 22 (6%) 373 0.72189 1 0.52345 1 0.47003 1 0.58258 1 0.10848 0.936 1 1 1 1 0.61422 1 0.93988 1 0.47292 1 0.13754 1 0.88728 1 1 1 NFE2L2 24 (6%) 371 0.3163 1 0.72306 1 0.1493 1 0.062349 0.9 0.82343 1 0.11528 0.941 0.029156 0.797 1 1 0.6858 1 0.67716 1 0.4657 1 0.071279 0.9 1 1 CUL1 19 (5%) 376 0.84392 1 0.57911 1 0.73116 1 0.78183 1 0.3329 1 1 1 0.79102 1 0.6127 1 0.41752 1 0.1697 1 0.47982 1 0.87846 1 0.33698 1 HLA-A 5 (1%) 390 0.4715 1 0.87745 1 0.39828 1 0.03599 0.797 0.68268 1 1 1 1 1 1 1 NA NA NA NA 0.87687 1 1 1 1 1 GNA13 12 (3%) 383 0.69633 1 0.61369 1 0.63892 1 0.63695 1 0.70815 1 1 1 0.31146 1 1 1 0.071535 0.9 0.71688 1 0.19497 1 0.5573 1 0.22012 1 NUDT11 7 (2%) 388 0.80931 1 0.13999 1 1 1 0.51011 1 0.73119 1 1 1 0.19785 1 1 1 NA NA NA NA 0.98546 1 1 1 1 1 MBD1 12 (3%) 383 0.46987 1 0.59929 1 0.16198 1 1 1 0.34066 1 1 1 0.31146 1 0.49199 1 0.040879 0.797 0.43742 1 0.092357 0.917 0.40096 1 1 1 SCARF2 8 (2%) 387 0.27859 1 0.14408 1 0.35706 1 1 1 0.45933 1 1 1 0.43082 1 1 1 0.96954 1 0.6461 1 0.44392 1 0.75768 1 1 1 FOXQ1 14 (4%) 381 0.28842 1 0.38547 1 0.64801 1 1 1 0.32713 1 1 1 0.76237 1 1 1 NA NA 0.070366 0.9 0.63502 1 0.71751 1 1 1 FAM47C 21 (5%) 374 0.083424 0.915 0.77436 1 0.39832 1 0.95042 1 0.03922 0.797 1 1 0.036244 0.797 0.61422 1 0.84553 1 0.98906 1 0.072426 0.9 0.89006 1 0.38217 1 METTL3 17 (4%) 378 0.072724 0.9 0.89171 1 0.37319 1 0.35799 1 0.947 1 1 1 0.57643 1 0.59675 1 0.096389 0.927 0.24806 1 0.14527 1 0.31391 1 1 1 ZNF185 5 (1%) 390 0.96508 1 0.38006 1 0.47903 1 1 1 0.46292 1 1 1 0.33361 1 1 1 NA NA NA NA 0.10727 0.936 1 1 1 1 ERBB2 48 (12%) 347 0.031304 0.797 0.26689 1 0.6256 1 0.93159 1 0.46803 1 0.60658 1 0.72625 1 0.48906 1 0.67961 1 0.91542 1 0.19083 1 0.72401 1 1 1 ATM 53 (13%) 342 0.32391 1 0.66343 1 0.74789 1 0.79754 1 0.36213 1 0.3679 1 0.24137 1 1 1 0.083396 0.915 0.21641 1 0.21637 1 0.3487 1 0.31259 1 UNC93B1 7 (2%) 388 0.30455 1 0.53648 1 0.59079 1 0.53653 1 0.32975 1 1 1 0.19785 1 1 1 NA NA NA NA 0.30136 1 1 1 1 1 SF1 10 (3%) 385 0.51099 1 0.087872 0.917 0.1147 0.941 1 1 0.01434 0.797 1 1 0.070084 0.9 1 1 0.70098 1 0.3344 1 0.057465 0.89 0.62024 1 1 1 BCL2L1 4 (1%) 391 0.027541 0.797 0.74555 1 0.34571 1 0.28876 1 1 1 1 1 0.57633 1 1 1 NA NA NA NA 0.9408 1 1 1 1 1 DNAH6 16 (4%) 379 0.95746 1 0.94369 1 0.21337 1 0.159 1 0.63649 1 1 1 0.77089 1 0.54724 1 0.7474 1 0.76161 1 0.072328 0.9 0.87432 1 0.28892 1 HES1 11 (3%) 384 0.37497 1 0.051925 0.852 0.93311 1 1 1 0.64064 1 1 1 0.7358 1 1 1 NA NA 0.16479 1 0.55933 1 0.4023 1 1 1 ERBB3 41 (10%) 354 0.43662 1 0.7405 1 0.52547 1 0.76912 1 0.50604 1 0.60658 1 0.19325 1 0.70726 1 0.074 0.9 0.74199 1 0.53206 1 0.059239 0.895 0.19144 1 TXNIP 17 (4%) 378 0.92555 1 0.2096 1 0.76754 1 0.22962 1 0.82663 1 1 1 1 1 0.6127 1 0.19498 1 0.93343 1 0.67413 1 0.063029 0.9 0.27224 1 THRAP3 14 (4%) 381 0.44227 1 0.091429 0.917 0.20432 1 0.80147 1 0.48667 1 1 1 0.76237 1 0.54724 1 0.6857 1 0.2572 1 0.038421 0.797 0.41685 1 0.033911 0.797 SPTAN1 45 (11%) 350 0.049579 0.852 0.052581 0.852 0.41691 1 0.21914 1 0.59609 1 1 1 0.10545 0.936 1 1 0.96346 1 0.38739 1 0.32294 1 0.5972 1 0.22524 1 ARID1B 23 (6%) 372 0.85208 1 0.3589 1 0.4328 1 0.40856 1 0.27398 1 0.19472 1 1 1 0.62053 1 0.6857 1 0.051769 0.852 0.10493 0.936 0.38372 1 1 1 NRAS 7 (2%) 388 0.20705 1 0.37013 1 0.33351 1 0.45549 1 0.52802 1 1 1 0.19785 1 1 1 NA NA 0.19348 1 0.36172 1 0.081169 0.915 1 1 RPTN 15 (4%) 380 0.94909 1 0.99077 1 0.26521 1 0.8526 1 0.088869 0.917 1 1 0.76845 1 0.57268 1 0.89519 1 0.045984 0.852 0.14497 1 0.51615 1 1 1 RAI1 21 (5%) 374 0.10079 0.936 0.76908 1 0.63006 1 1 1 0.12234 0.958 0.11528 0.941 0.30639 1 0.61693 1 0.66454 1 0.81411 1 0.14089 1 1 1 0.32129 1 TMCO4 12 (3%) 383 0.92991 1 0.8549 1 0.68251 1 0.49631 1 0.70833 1 0.47212 1 0.73855 1 1 1 0.41752 1 0.63577 1 0.72543 1 0.03327 0.797 1 1 CNOT1 21 (5%) 374 0.011776 0.797 0.39194 1 0.19384 1 0.48341 1 0.7549 1 1 1 0.30639 1 0.61693 1 0.026902 0.797 0.017651 0.797 0.21431 1 0.62921 1 0.0067432 0.797 PARD3 22 (6%) 373 0.29442 1 0.70557 1 0.58635 1 0.23671 1 0.27727 1 1 1 0.021132 0.797 0.61693 1 0.0094471 0.797 0.5709 1 0.3492 1 0.28335 1 0.078674 0.91 EZR 12 (3%) 383 0.015488 0.797 0.43213 1 0.34494 1 0.33968 1 0.51252 1 0.29098 1 0.5158 1 0.49199 1 0.321 1 0.15379 1 0.135 1 0.20498 1 1 1 MOAP1 7 (2%) 388 0.040804 0.797 0.10743 0.936 0.8086 1 0.86083 1 1 1 1 1 1 1 0.28521 1 0.24635 1 0.6058 1 1 1 0.71246 1 1 1 SF3B1 24 (6%) 371 0.52135 1 0.034974 0.797 0.18582 1 0.5191 1 0.72035 1 1 1 0.15209 1 0.62494 1 0.0096827 0.797 0.94146 1 0.83857 1 0.39537 1 1 1 RUNX1 13 (3%) 382 0.55392 1 0.72867 1 0.44526 1 0.23932 1 0.7073 1 1 1 0.52834 1 0.46202 1 0.68687 1 0.9468 1 0.092157 0.917 0.48293 1 1 1 MEGF8 20 (5%) 375 0.31997 1 0.75541 1 0.49774 1 0.62348 1 0.43244 1 1 1 0.11866 0.947 0.61254 1 0.82886 1 0.028453 0.797 0.24211 1 0.53675 1 0.30527 1 CASP8 14 (4%) 381 0.23113 1 0.79072 1 0.30298 1 0.71907 1 0.59047 1 1 1 1 1 1 1 0.89519 1 0.56849 1 0.56278 1 0.83784 1 1 1 DAZAP1 6 (2%) 389 0.35687 1 0.91366 1 0.051839 0.852 0.21479 1 1 1 1 1 1 1 1 1 0.321 1 0.20626 1 0.71169 1 1 1 1 1 USP28 13 (3%) 382 0.47079 1 0.95751 1 1 1 0.92747 1 0.42026 1 0.3693 1 1 1 1 1 0.14096 1 0.53521 1 0.47847 1 0.83735 1 1 1 SETD2 27 (7%) 368 0.61509 1 0.8376 1 0.52913 1 0.80689 1 0.4955 1 1 1 0.82084 1 1 1 0.049898 0.852 0.032102 0.797 0.70005 1 0.76519 1 1 1 EME1 5 (1%) 390 0.65769 1 0.0554 0.871 0.46698 1 0.57492 1 1 1 1 1 1 1 1 1 NA NA NA NA NA NA 0.33215 1 1 1 ADC 5 (1%) 390 0.48108 1 0.2144 1 0.46785 1 0.57732 1 1 1 1 1 1 1 1 1 0.47685 1 NA NA 0.92527 1 0.33129 1 1 1 CNOT3 10 (3%) 385 0.10842 0.936 0.49676 1 0.92882 1 1 1 0.68441 1 0.3693 1 0.46393 1 1 1 NA NA 0.72106 1 0.8829 1 0.24604 1 1 1 SSH3 15 (4%) 380 0.096866 0.927 0.28738 1 0.43032 1 0.15722 1 0.2206 1 1 1 0.76845 1 1 1 NA NA 0.65595 1 0.20034 1 0.59801 1 1 1 AHR 22 (6%) 373 0.31832 1 0.95849 1 0.20516 1 0.3625 1 0.43549 1 0.47212 1 0.61587 1 1 1 0.64861 1 0.88507 1 0.97056 1 1 1 0.36742 1 EIF4A2 11 (3%) 384 0.50071 1 0.93149 1 0.61795 1 0.20188 1 0.52085 1 0.33118 1 0.3019 1 1 1 0.56685 1 0.79227 1 0.66884 1 0.76798 1 1 1 EPHA2 19 (5%) 376 0.57856 1 0.11005 0.937 0.52007 1 0.36064 1 0.01453 0.797 0.3693 1 0.055165 0.871 0.61199 1 0.53264 1 0.19384 1 0.99862 1 0.11813 0.947 1 1 OGDH 19 (5%) 376 0.2298 1 0.34143 1 0.88653 1 0.94092 1 1 1 1 1 0.42378 1 1 1 0.47601 1 0.28978 1 0.54546 1 0.27804 1 0.33698 1 POU3F1 3 (1%) 392 0.33357 1 0.69314 1 0.083209 0.915 0.57633 1 0.059489 0.895 NA NA 1 1 1 1 NA NA NA NA 0.027503 0.797 1 1 1 1