Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.119 0.218 -9999.0 0.0 -0.414 106.0 106.0 MAP3K8 0.021 0.036 -9999.0 0.0 -0.469 2.0 2.0 FOS -0.086 0.17 -9999.0 0.0 -0.396 63.0 63.0 PRKCA 0.011 0.052 -9999.0 0.0 -0.471 4.0 4.0 PTPN7 0.007 0.067 0.214 2.0 -0.471 6.0 8.0 HRAS 0.024 0.008 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.121 0.218 -9999.0 0.0 -0.471 112.0 112.0 NRAS 0.027 0.002 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.037 0.026 0.194 1.0 -9999.0 0.0 1.0 MAPK3 -0.044 0.131 -9999.0 0.0 -0.552 14.0 14.0 MAP2K1 -0.104 0.203 -9999.0 0.0 -0.404 116.0 116.0 ELK1 0.01 0.027 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.101 0.187 -9999.0 0.0 -0.39 113.0 113.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 128.0 128.0 MAPK1 -0.046 0.134 -9999.0 0.0 -0.541 16.0 16.0 RAF1 -0.094 0.182 0.223 1.0 -0.389 105.0 106.0 KRAS 0.026 0.016 0.327 1.0 -9999.0 0.0 1.0