Clinical Features	Time to Death		YEARS_TO_BIRTH		PATHOLOGIC_STAGE		PATHOLOGY_T_STAGE		PATHOLOGY_N_STAGE		PATHOLOGY_M_STAGE		GENDER		RADIATION_THERAPY		KARNOFSKY_PERFORMANCE_SCORE		HISTOLOGICAL_TYPE		NUMBER_PACK_YEARS_SMOKED		RESIDUAL_TUMOR		NUMBER_OF_LYMPH_NODES		RACE		ETHNICITY	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
TP53	153 (83%)	32	0.92977	1	0.00018472	0.0409	0.27632	1	0.42353	1	0.44317	1	1	1	0.094641	0.947	0.15873	1	0.12572	0.992	0.0035013	0.242	0.97486	1	0.36543	1	0.36802	1	0.00014	0.0409	1	1
SMAD4	13 (7%)	172	0.38929	1	0.94644	1	0.15866	1	0.60532	1	0.03875	0.74	1	1	0.6958	1	0.73054	1	NA	NA	0.042632	0.74	0.71607	1	0.14862	1	0.12418	0.989	0.4198	1	1	1
CDKN2A	19 (10%)	166	0.34197	1	0.5594	1	0.22532	1	1	1	0.065049	0.826	0.60045	1	0.48865	1	0.031986	0.669	0.83633	1	0.027375	0.669	0.51784	1	0.62447	1	0.28319	1	0.3652	1	0.37979	1
NFE2L2	16 (9%)	169	0.98304	1	0.045892	0.774	0.18938	1	0.059039	0.826	0.49776	1	1	1	1	1	0.74232	1	0.58143	1	0.00034981	0.0525	0.13692	1	0.32743	1	0.24487	1	4e-05	0.036	0.58665	1
MLL2	32 (17%)	153	0.69177	1	0.73828	1	0.2704	1	0.51538	1	0.58526	1	0.68498	1	0.094641	0.947	0.0645	0.826	0.11496	0.967	0.11906	0.974	0.23443	1	0.46819	1	0.81785	1	0.01825	0.602	1	1
ZNF750	10 (5%)	175	0.84892	1	0.72686	1	0.54577	1	0.35025	1	0.30558	1	1	1	1	1	0.23777	1	0.086935	0.938	0.019081	0.602	0.58236	1	0.57017	1	0.90469	1	0.01731	0.599	1	1
TGFBR2	15 (8%)	170	0.57011	1	0.18316	1	0.18778	1	0.88714	1	0.081009	0.9	0.51871	1	0.2414	1	1	1	0.3557	1	0.59588	1	0.12801	1	0.84716	1	0.42794	1	0.84169	1	1	1
FBXW7	13 (7%)	172	0.25324	1	0.3034	1	0.62198	1	0.56672	1	0.089009	0.942	0.44779	1	0.1015	0.947	0.51825	1	0.060963	0.826	0.15201	1	0.55698	1	0.78024	1	0.28385	1	0.42371	1	0.062129	0.826
PKD2	7 (4%)	178	0.3886	1	0.16578	1	0.98176	1	0.60154	1	0.7791	1	1	1	0.59601	1	0.038768	0.74	0.073184	0.834	0.4465	1	0.98352	1	1	1	0.93292	1	0.28225	1	1	1
ARID1A	15 (8%)	170	0.87365	1	0.061193	0.826	0.57534	1	0.54962	1	0.21112	1	1	1	0.048151	0.774	0.022492	0.642	NA	NA	0.01362	0.599	0.70905	1	0.37061	1	0.28434	1	0.17504	1	0.18134	1
ERBB2	11 (6%)	174	0.22204	1	0.28254	1	0.68525	1	1	1	0.39069	1	1	1	0.6644	1	0.11349	0.964	NA	NA	0.00022721	0.0409	0.79579	1	1	1	0.52548	1	0.10652	0.947	0.2863	1
PTCH1	12 (6%)	173	0.39289	1	0.63942	1	0.66	1	0.79168	1	0.3352	1	0.44779	1	1	1	0.47641	1	0.28807	1	0.13629	1	0.58861	1	0.49646	1	0.84312	1	0.065169	0.826	0.23532	1
KIAA2018	13 (7%)	172	0.013558	0.599	0.0019643	0.168	0.49731	1	0.79499	1	0.22297	1	0.44779	1	1	1	0.73284	1	0.3229	1	0.15201	1	0.0020577	0.168	0.44983	1	0.94287	1	0.65689	1	0.33441	1
FAM108A1	4 (2%)	181	0.069308	0.832	0.74812	1	0.87664	1	0.57956	1	1	1	1	1	0.10231	0.947	1	1	NA	NA	1	1	NA	NA	1	1	0.5455	1	1	1	1	1
PAXIP1	10 (5%)	175	0.55198	1	0.19152	1	0.29599	1	0.1365	1	0.74651	1	0.098352	0.947	0.64167	1	0.69598	1	0.85296	1	0.74888	1	0.25137	1	1	1	0.5113	1	0.78535	1	1	1
MGC29506	4 (2%)	181	0.24439	1	0.67083	1	0.28119	1	0.68571	1	0.40028	1	0.22825	1	0.47094	1	0.57336	1	NA	NA	1	1	NA	NA	1	1	0.28717	1	0.26787	1	NA	NA
C10ORF76	6 (3%)	179	0.39704	1	0.51982	1	0.25715	1	0.26171	1	0.16553	1	1	1	0.04127	0.74	1	1	NA	NA	0.68371	1	0.47183	1	0.59234	1	0.75612	1	0.73202	1	1	1
IPP	6 (3%)	179	0.48959	1	0.0090704	0.544	0.7771	1	0.29002	1	0.30199	1	1	1	1	1	0.34019	1	NA	NA	0.43014	1	0.48885	1	1	1	0.60308	1	0.62851	1	1	1
DNAH10	19 (10%)	166	0.24115	1	0.29069	1	0.00162	0.168	0.39546	1	0.56667	1	0.59805	1	1	1	1	1	NA	NA	0.22588	1	0.22615	1	0.88679	1	0.10074	0.947	0.19145	1	1	1
RIC3	4 (2%)	181	0.35908	1	0.0028845	0.216	0.21321	1	0.83611	1	0.32854	1	1	1	0.47094	1	1	1	NA	NA	0.3528	1	0.031658	0.669	0.2368	1	0.5946	1	0.62761	1	NA	NA
HMMR	4 (2%)	181	0.65087	1	0.42757	1	0.5358	1	0.68907	1	1	1	1	1	1	1	1	1	NA	NA	1	1	NA	NA	0.4537	1	0.40856	1	1	1	1	1
PIAS1	5 (3%)	180	0.66544	1	0.87881	1	0.2919	1	0.20903	1	0.36482	1	1	1	1	1	1	1	NA	NA	0.67281	1	0.36368	1	1	1	0.82045	1	0.62945	1	1	1
ITGA6	7 (4%)	178	0.52947	1	0.040891	0.74	0.85203	1	0.54814	1	1	1	1	1	1	1	0.038768	0.74	0.03848	0.74	1	1	0.39578	1	0.28753	1	0.3997	1	0.46509	1	1	1
ASTE1	5 (3%)	180	0.29887	1	0.016709	0.599	0.20882	1	0.41552	1	0.14797	1	1	1	0.15527	1	0.57336	1	NA	NA	0.024273	0.643	0.51147	1	0.29882	1	0.25645	1	0.62802	1	1	1
KPNA1	6 (3%)	179	0.40006	1	0.89819	1	0.59093	1	0.49928	1	0.39089	1	1	1	0.59488	1	0.6481	1	NA	NA	0.43014	1	0.84439	1	0.59797	1	0.85666	1	1	1	1	1
LIMA1	8 (4%)	177	0.63913	1	0.10651	0.947	0.087549	0.938	0.04679	0.774	1	1	0.40897	1	0.094078	0.947	0.68138	1	NA	NA	0.15675	1	0.84315	1	1	1	0.36789	1	0.56756	1	1	1
FAM65B	8 (4%)	177	0.51333	1	0.32579	1	0.66793	1	0.59614	1	0.90333	1	0.36773	1	1	1	0.19229	1	NA	NA	0.72212	1	0.6104	1	1	1	0.63278	1	1	1	1	1
CORO7	7 (4%)	178	0.071412	0.834	0.38172	1	0.62254	1	0.35787	1	0.56249	1	1	1	0.27111	1	0.32928	1	NA	NA	0.26404	1	0.31632	1	0.02963	0.669	0.76795	1	0.32149	1	1	1
ANAPC1	5 (3%)	180	0.20321	1	0.22576	1	0.43781	1	1	1	0.3657	1	1	1	0.022884	0.642	0.32928	1	NA	NA	0.67281	1	NA	NA	1	1	0.55832	1	1	1	1	1
IVL	15 (8%)	170	0.13773	1	0.0017467	0.168	0.060089	0.826	0.69585	1	0.1858	1	0.40897	1	0.46312	1	0.11874	0.974	NA	NA	0.00020758	0.0409	0.015294	0.599	0.56887	1	0.57406	1	0.04277	0.74	0.031406	0.669
PIK3CA	19 (10%)	166	0.67202	1	0.020513	0.615	0.95327	1	0.071829	0.834	0.82241	1	1	1	0.74402	1	0.77117	1	0.41546	1	0.15071	1	0.15207	1	0.87484	1	0.49837	1	0.59278	1	0.56994	1
RB1	7 (4%)	178	0.066865	0.83	0.69479	1	0.515	1	0.36997	1	0.33432	1	1	1	0.27111	1	0.19229	1	0.45846	1	1	1	0.28857	1	1	1	0.91089	1	1	1	1	1
EIF4EBP2	3 (2%)	182	0.67749	1	0.1186	0.974	NA	NA	NA	NA	NA	NA	1	1	1	1	0.56986	1	NA	NA	0.10938	0.947	NA	NA	NA	NA	NA	NA	0.59564	1	1	1
SCD	3 (2%)	182	0.99316	1	0.10513	0.947	0.15261	1	0.47365	1	0.02911	0.669	1	1	0.37879	1	1	1	NA	NA	0.6091	1	NA	NA	1	1	0.015933	0.599	NA	NA	1	1
MKL2	6 (3%)	179	0.67466	1	0.014579	0.599	0.30461	1	1	1	0.36472	1	1	1	1	1	0.32928	1	NA	NA	0.10707	0.947	0.030055	0.669	0.30169	1	0.55832	1	0.32536	1	1	1
NOTCH1	18 (10%)	167	0.92419	1	0.31117	1	0.46456	1	0.34974	1	0.62748	1	0.60045	1	1	1	0.3654	1	0.89314	1	0.025186	0.648	0.36706	1	0.53669	1	0.2439	1	0.075849	0.853	0.56994	1
KLF3	3 (2%)	182	0.65979	1	0.012755	0.599	0.4219	1	1	1	0.064889	0.826	1	1	0.37879	1	0.56986	1	NA	NA	0.10938	0.947	NA	NA	1	1	0.54042	1	0.59777	1	NA	NA
IL10RA	3 (2%)	182	0.95206	1	0.84905	1	0.46585	1	0.62894	1	0.72657	1	1	1	1	1	0.16306	1	NA	NA	0.6091	1	NA	NA	1	1	0.71911	1	0.59633	1	1	1
RAD17	4 (2%)	181	0.18579	1	0.96234	1	0.55239	1	1	1	0.61096	1	1	1	1	1	1	1	0.92616	1	0.62199	1	0.8606	1	0.23987	1	0.62432	1	1	1	1	1
KPNB1	6 (3%)	179	0.54053	1	0.083764	0.919	0.94459	1	0.6945	1	0.63894	1	1	1	0.59488	1	0.6481	1	0.1645	1	0.21311	1	0.80814	1	0.59628	1	0.39993	1	0.11066	0.949	1	1
ZBED4	5 (3%)	180	0.69985	1	0.90895	1	1	1	0.75385	1	0.67163	1	1	1	1	1	0.27322	1	0.1645	1	0.36998	1	0.93549	1	0.30164	1	NA	NA	0.26908	1	1	1
NAA16	6 (3%)	179	0.77652	1	0.94127	1	0.28687	1	0.04817	0.774	0.056559	0.826	1	1	0.59488	1	0.6481	1	NA	NA	0.43014	1	0.73277	1	0.23037	1	0.26888	1	1	1	1	1
CNNM2	7 (4%)	178	0.26017	1	0.064798	0.826	0.63448	1	0.34064	1	0.36859	1	0.32396	1	1	1	0.6787	1	NA	NA	0.26404	1	0.023545	0.642	1	1	0.25038	1	0.73562	1	1	1
HLA-B	7 (4%)	178	0.23249	1	0.87132	1	0.18829	1	1	1	0.64073	1	1	1	0.27111	1	0.32928	1	NA	NA	1	1	0.26475	1	1	1	0.86096	1	0.35166	1	1	1
PLXNB2	12 (6%)	173	0.6891	1	0.64141	1	0.49111	1	0.53139	1	0.31901	1	1	1	1	1	0.47641	1	0.29928	1	1	1	0.65832	1	1	1	0.55832	1	0.50525	1	0.46285	1
PTEN	7 (4%)	178	0.37107	1	0.39159	1	0.76548	1	0.24263	1	0.70525	1	1	1	0.27111	1	0.6787	1	0.53519	1	0.4465	1	0.98352	1	1	1	0.89074	1	0.52763	1	1	1
CPT1B	5 (3%)	180	0.41281	1	0.97297	1	0.74835	1	0.3604	1	0.14479	1	1	1	0.54986	1	1	1	NA	NA	1	1	0.59567	1	1	1	0.13103	1	0.16577	1	0.12423	0.989
CAMTA1	9 (5%)	176	0.81605	1	0.15263	1	0.34538	1	0.86051	1	0.14144	1	1	1	0.62161	1	1	1	NA	NA	0.31642	1	0.37803	1	0.39637	1	0.66375	1	0.73779	1	1	1
OTUD7B	7 (4%)	178	0.39175	1	0.32575	1	0.61731	1	0.2895	1	0.49424	1	1	1	0.065152	0.826	0.6481	1	NA	NA	0.71243	1	0.31379	1	0.59893	1	0.80545	1	0.068249	0.83	1	1
ARRB1	5 (3%)	180	0.75863	1	0.97635	1	0.64234	1	0.57798	1	1	1	1	1	1	1	1	1	NA	NA	0.67281	1	0.33669	1	0.45165	1	0.78295	1	1	1	1	1
KIAA1704	3 (2%)	182	0.23054	1	0.14653	1	0.19039	1	1	1	0.02863	0.669	1	1	0.37879	1	0.56986	1	NA	NA	0.6091	1	NA	NA	1	1	0.18811	1	1	1	NA	NA
RNF169	6 (3%)	179	0.72437	1	0.75348	1	0.67897	1	0.56057	1	1	1	0.27751	1	0.59488	1	0.10832	0.947	0.073184	0.834	0.43014	1	0.67908	1	1	1	0.51875	1	1	1	1	1
RBPJL	6 (3%)	179	0.16471	1	0.16045	1	1	1	0.44816	1	0.85513	1	1	1	0.21226	1	0.10832	0.947	NA	NA	0.68371	1	0.36879	1	0.35874	1	0.56276	1	1	1	1	1
MGAT5B	8 (4%)	177	0.053286	0.826	0.46784	1	0.18919	1	0.34142	1	0.01601	0.599	0.27751	1	1	1	1	1	0.36214	1	1	1	0.60474	1	0.41437	1	0.33631	1	0.73854	1	0.019411	0.602
LRRC32	9 (5%)	176	0.094581	0.947	0.14632	1	0.93539	1	0.37185	1	0.81699	1	1	1	0.36099	1	0.68138	1	NA	NA	0.74002	1	0.2377	1	0.00073999	0.0951	0.13608	1	0.73881	1	1	1
TCHH	14 (8%)	171	0.23953	1	0.95444	1	0.95175	1	0.12416	0.989	0.86627	1	1	1	1	1	0.050111	0.791	0.60183	1	0.78447	1	0.81963	1	1	1	0.52104	1	0.067459	0.83	1	1
SLC22A2	4 (2%)	181	0.84956	1	0.098368	0.947	0.36298	1	0.25971	1	0.47687	1	0.22825	1	0.47094	1	0.16306	1	NA	NA	0.3528	1	NA	NA	1	1	0.30158	1	0.40456	1	1	1
PCDH15	21 (11%)	164	0.7692	1	0.50901	1	0.098519	0.947	0.57157	1	0.01432	0.599	1	1	0.32096	1	1	1	0.59142	1	0.24622	1	0.22121	1	0.48385	1	0.01222	0.599	0.32391	1	0.53643	1
KIAA1549	8 (4%)	177	0.73312	1	0.1683	1	0.74937	1	0.060719	0.826	0.40856	1	1	1	0.33012	1	0.6787	1	NA	NA	1	1	0.18742	1	1	1	0.83441	1	0.56527	1	0.18134	1
SETBP1	14 (8%)	171	0.29978	1	0.0057246	0.368	0.61546	1	0.2906	1	0.86821	1	0.58142	1	1	1	1	1	0.55725	1	0.094949	0.947	0.21105	1	0.42949	1	0.53636	1	0.04148	0.74	0.33441	1