Clinical feature	Statistical test	Significant variables	Associated with	               	Associated with	
DAYS_TO_DEATH_OR_LAST_FUP	Cox regression test	N=0	 	 	 	 
AGE	Spearman correlation test	N=2	older	N=2	younger	N=0
AGE_mutation rate	Linear Regression Analysis	N=2	 	 	 	 
PATHOLOGIC_STAGE	Kruskal-Wallis test	N=0	 	 	 	 
PATHOLOGY_T_STAGE	Spearman correlation test	N=0	 	 	 	 
PATHOLOGY_N_STAGE	Spearman correlation test	N=0	 	 	 	 
PATHOLOGY_M_STAGE	Wilcoxon test	N=0	 	 	 	 
GENDER	Wilcoxon test	N=0	 	 	 	 
RADIATION_THERAPY	Wilcoxon test	N=1	yes	N=1	no	N=0
KARNOFSKY_PERFORMANCE_SCORE	Spearman correlation test	N=0	 	 	 	 
HISTOLOGICAL_TYPE	Wilcoxon test	N=2	esophagus squamous cell carcinoma	N=2	esophagus adenocarcinoma, nos	N=0
NUMBER_PACK_YEARS_SMOKED	Spearman correlation test	N=0	 	 	 	 
RESIDUAL_TUMOR	Kruskal-Wallis test	N=1	 	 	 	 
NUMBER_OF_LYMPH_NODES	Spearman correlation test	N=0	 	 	 	 
RACE	Kruskal-Wallis test	N=2	 	 	 	 
ETHNICITY	Wilcoxon test	N=0