Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		MIR_CNMF		MIR_CHIERARCHICAL		CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
TP53	80 (28%)	203	0.00074999	0.015	9.9999e-06	0.000514	0.00079999	0.0152	0.20208	0.769	0.00033	0.00792	5e-05	0.0018	0.0069799	0.0838	0.04751	0.356	0.00124	0.0213	0.00064999	0.0138
PIK3R1	32 (11%)	251	0.41545	0.951	0.19111	0.762	0.061809	0.412	0.5313	1	0.074479	0.452	0.41734	0.951	0.21464	0.777	0.057089	0.4	0.46897	0.993	0.2198	0.777
RB1	24 (8%)	259	0.084059	0.477	0.01768	0.177	0.10472	0.524	0.92184	1	0.18988	0.762	0.01948	0.182	0.81589	1	0.54019	1	0.078149	0.461	0.57696	1
NF1	29 (10%)	254	0.10176	0.523	0.00039	0.00877	0.0332	0.266	0.93124	1	0.0076199	0.0885	0.059329	0.403	0.052919	0.381	0.01207	0.132	0.48157	0.993	0.45025	0.982
PTEN	87 (31%)	196	0.15067	0.687	0.075329	0.452	0.04468	0.342	0.64441	1	0.10034	0.523	0.02731	0.234	0.24712	0.78	0.38172	0.922	0.42086	0.953	0.64571	1
IDH1	14 (5%)	269	0.00022	0.00609	9.9999e-06	0.000514	7.9999e-05	0.0024	0.00289	0.0452	9.9999e-06	0.000514	3e-05	0.00135	0.26759	0.813	0.0068099	0.0838	0.00098999	0.0178	9.9999e-06	0.000514
PIK3CA	27 (10%)	256	0.92097	1	0.28823	0.837	0.27418	0.813	0.86086	1	0.74444	1	0.38093	0.922	0.81101	1	0.40469	0.946	0.48547	0.993	0.23229	0.777
STAG2	12 (4%)	271	0.49209	0.995	0.69969	1	0.52678	1	0.59339	1	0.48813	0.993	0.15527	0.691	0.27748	0.813	0.33536	0.875	0.42711	0.961	0.10445	0.524
SLC26A3	7 (2%)	276	0.84693	1	0.76736	1	0.5797	1	0.36522	0.908	0.7026	1	0.23501	0.777	0.48471	0.993	0.30955	0.854	0.11243	0.547	0.16413	0.721
SEMG1	8 (3%)	275	0.9574	1	0.17633	0.738	0.95775	1	1	1	0.3403	0.875	0.27123	0.813	NA	NA	NA	NA	1	1	0.33651	0.875
KDR	8 (3%)	275	0.21936	0.777	0.65508	1	0.24461	0.779	0.51187	1	0.37475	0.918	0.34014	0.875	0.15548	0.691	0.73652	1	NA	NA	NA	NA
RPL5	7 (2%)	276	0.39914	0.939	0.51003	1	0.9073	1	0.46914	0.993	0.79721	1	NA	NA	0.55207	1	0.68965	1	0.46155	0.993	1	1
ATRX	16 (6%)	267	0.00358	0.0516	9.9999e-06	0.000514	0.01622	0.167	0.01845	0.18	9.9999e-06	0.000514	5.9999e-05	0.00196	0.55403	1	0.01355	0.143	0.00255	0.0417	0.00024	0.00617
MAP3K1	6 (2%)	277	0.92957	1	0.73034	1	0.75976	1	0.64619	1	0.65405	1	NA	NA	NA	NA	NA	NA	0.5639	1	1	1
BRAF	6 (2%)	277	0.59788	1	0.71161	1	0.3166	0.857	0.02855	0.234	0.096699	0.512	NA	NA	1	1	0.77994	1	0.79367	1	1	1
EGFR	74 (26%)	209	0.086139	0.477	0.057769	0.4	0.27766	0.813	0.13949	0.654	4e-05	0.0016	0.00355	0.0516	0.25641	0.798	9.9999e-06	0.000514	0.02391	0.215	0.0060599	0.0808
TMPRSS6	6 (2%)	277	0.73122	1	0.70266	1	0.72554	1	0.26321	0.81	0.58341	1	1	1	0.90525	1	0.46942	0.993	0.57228	1	1	1
PRKCD	3 (1%)	280	0.081669	0.474	0.085129	0.477	0.23452	0.777	1	1	0.61742	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
TP63	6 (2%)	277	0.92962	1	0.72835	1	0.31598	0.857	0.64771	1	0.76272	1	NA	NA	0.03702	0.29	0.38806	0.925	0.23864	0.777	0.10874	0.536
PDGFRA	11 (4%)	272	0.0097699	0.11	0.14794	0.683	1	1	0.13981	0.654	0.4961	0.998	0.21357	0.777	0.29955	0.849	0.73187	1	0.02686	0.234	0.00491	0.068
CHD8	9 (3%)	274	0.77512	1	0.53215	1	0.17214	0.738	0.64611	1	0.23309	0.777	NA	NA	0.3106	0.854	0.91527	1	0.26877	0.813	0.61154	1
IL4R	8 (3%)	275	0.84597	1	0.38751	0.925	0.74429	1	0.80462	1	0.53	1	0.44655	0.982	0.22709	0.777	0.88574	1	0.45015	0.982	0.80035	1
REN	5 (2%)	278	0.30181	0.849	0.41416	0.951	0.069009	0.444	0.51326	1	0.74156	1	NA	NA	0.55317	1	1	1	NA	NA	NA	NA
CD209	5 (2%)	278	0.83179	1	1	1	0.32797	0.875	0.60859	1	0.83835	1	NA	NA	0.90406	1	1	1	NA	NA	NA	NA
FBN3	11 (4%)	272	0.348	0.889	0.30786	0.854	1	1	0.92061	1	0.088049	0.48	1	1	0.01968	0.182	0.66433	1	0.85427	1	1	1
MMP13	5 (2%)	278	0.83153	1	0.22007	0.777	0.76238	1	0.04927	0.362	0.2045	0.769	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
TCF12	4 (1%)	279	1	1	0.48117	0.993	0.58739	1	0.25702	0.798	1	1	NA	NA	0.074789	0.452	1	1	NA	NA	NA	NA
LZTR1	10 (4%)	273	0.80381	1	0.51557	1	0.4669	0.993	0.70203	1	0.37196	0.917	0.33611	0.875	0.2005	0.769	0.56284	1	0.16787	0.728	0.75148	1
ZDHHC4	3 (1%)	280	NA	NA	NA	NA	0.23563	0.777	1	1	0.18256	0.754	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
IL18RAP	7 (2%)	276	0.072029	0.452	0.22613	0.777	0.0065999	0.0838	0.17478	0.738	0.48484	0.993	1	1	0.36591	0.908	0.61373	1	0.68452	1	0.3384	0.875
ODF4	3 (1%)	280	0.87588	1	0.35047	0.889	1	1	0.19531	0.764	0.79415	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
KEL	15 (5%)	268	0.29251	0.842	0.20939	0.777	0.83468	1	0.88558	1	0.11458	0.55	0.18424	0.754	0.67534	1	0.59718	1	0.48491	0.993	0.64866	1
TESK1	3 (1%)	280	0.20513	0.769	0.69764	1	0.39217	0.929	0.60247	1	0.24407	0.779	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
MUC17	22 (8%)	261	0.062949	0.412	0.19271	0.762	0.8017	1	0.70305	1	0.29607	0.846	1	1	0.55327	1	0.090899	0.488	0.92745	1	1	1
FAM126B	4 (1%)	279	0.23956	0.777	0.02796	0.234	0.58742	1	0.44367	0.982	0.55013	1	0.68347	1	1	1	0.63036	1	NA	NA	NA	NA
DDX5	4 (1%)	279	0.41082	0.951	1	1	0.64552	1	0.44664	0.982	0.36139	0.908	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA