Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.001 0.106 0.315 49.0 -9999.0 0.0 49.0 KIRREL 0.002 0.102 -9999.0 0.0 -0.458 23.0 23.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.001 0.107 -9999.0 0.0 -0.316 49.0 49.0 PLCG1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.024 0.097 -9999.0 0.0 -0.301 24.0 24.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.002 0.062 -9999.0 0.0 -0.264 16.0 16.0 FYN -0.016 0.084 0.271 9.0 -0.281 24.0 33.0 mol:Ca2+ 0.022 0.094 -9999.0 0.0 -0.299 22.0 22.0 mol:DAG 0.023 0.095 -9999.0 0.0 -0.3 22.0 22.0 NPHS2 -0.013 0.068 -9999.0 0.0 -0.398 13.0 13.0 mol:IP3 0.023 0.095 -9999.0 0.0 -0.3 22.0 22.0 regulation of endocytosis 0.021 0.084 -9999.0 0.0 -0.272 21.0 21.0 Nephrin/NEPH1/podocin/Cholesterol 0.011 0.092 -9999.0 0.0 -0.243 54.0 54.0 establishment of cell polarity 0.001 0.106 -9999.0 0.0 -0.315 49.0 49.0 Nephrin/NEPH1/podocin/NCK1-2 0.032 0.09 -9999.0 0.0 -0.315 12.0 12.0 Nephrin/NEPH1/beta Arrestin2 0.023 0.085 -9999.0 0.0 -0.275 21.0 21.0 NPHS1 -0.02 0.098 -9999.0 0.0 -0.398 30.0 30.0 Nephrin/NEPH1/podocin 0.015 0.085 -9999.0 0.0 -0.282 24.0 24.0 TJP1 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.023 0.011 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.024 0.096 -9999.0 0.0 -0.301 22.0 22.0 CD2AP 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.025 0.098 -9999.0 0.0 -0.302 24.0 24.0 GRB2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.026 0.092 0.28 7.0 -0.265 36.0 43.0 cytoskeleton organization -0.01 0.071 0.231 3.0 -0.297 18.0 21.0 Nephrin/NEPH1 0.006 0.076 -9999.0 0.0 -0.218 48.0 48.0 Nephrin/NEPH1/ZO-1 0.02 0.091 -9999.0 0.0 -0.293 23.0 23.0