Clinical feature	Statistical test	Significant variables	Associated with	               	Associated with	
DAYS_TO_DEATH_OR_LAST_FUP	Cox regression test	N=2	 	N=NA	 	N=NA
AGE	Spearman correlation test	N=2	older	N=2	younger	N=0
AGE_mutation rate	Linear Regression Analysis	N=1	 	 	 	 
PATHOLOGIC_STAGE	Kruskal-Wallis test	N=2	 	 	 	 
PATHOLOGY_T_STAGE	Spearman correlation test	N=2	higher stage	N=2	lower stage	N=0
PATHOLOGY_N_STAGE	Spearman correlation test	N=2	higher stage	N=2	lower stage	N=0
PATHOLOGY_M_STAGE	Wilcoxon test	N=0	 	 	 	 
GENDER	Wilcoxon test	N=0	 	 	 	 
KARNOFSKY_PERFORMANCE_SCORE	Wilcoxon test	N=0	 	 	 	 
NUMBER_PACK_YEARS_SMOKED	Spearman correlation test	N=0	 	 	 	 
YEAR_OF_TOBACCO_SMOKING_ONSET	Spearman correlation test	N=0	 	 	 	 
RACE	Kruskal-Wallis test	N=0	 	 	 	 
ETHNICITY	Wilcoxon test	N=0