Clinical Features Time to Death YEARS_TO_BIRTH PATHOLOGIC_STAGE PATHOLOGY_T_STAGE PATHOLOGY_N_STAGE PATHOLOGY_M_STAGE GENDER KARNOFSKY_PERFORMANCE_SCORE NUMBER_PACK_YEARS_SMOKED YEAR_OF_TOBACCO_SMOKING_ONSET RACE ETHNICITY nCNV (%) nWild-Type logrank test_P logrank test_Q Wilcoxon-test_P Wilcoxon-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Wilcoxon-test_P Wilcoxon-test_Q Wilcoxon-test_P Wilcoxon-test_Q Wilcoxon-test_P Wilcoxon-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 22 (4%) 506 0.00037823 0.0117 0.075335 0.406 0.12853 0.541 0.20603 0.684 0.19079 0.668 0.35213 0.86 1 1 0.16792 0.627 NA NA NA NA 0.40292 0.885 0.61214 1 1q gain 51 (10%) 477 0.048902 0.315 0.029676 0.23 0.055239 0.344 0.079979 0.42 0.40605 0.885 0.68153 1 0.54127 1 0.40106 0.885 NA NA NA NA 0.63672 1 0.72705 1 2p gain 78 (15%) 450 0.65605 1 0.17696 0.648 0.26088 0.745 0.34877 0.854 0.74559 1 0.39263 0.885 1 1 0.7098 1 0.54307 1 NA NA 0.35857 0.87 0.76363 1 2q gain 79 (15%) 449 0.53862 1 0.21717 0.697 0.44788 0.935 0.54744 1 1 1 0.39249 0.885 0.52523 1 0.89912 1 0.54307 1 NA NA 0.33788 0.838 0.37411 0.884 3p gain 20 (4%) 508 0.041769 0.288 0.48197 0.96 0.085169 0.436 0.12899 0.541 0.038914 0.274 0.10741 0.498 0.47614 0.952 0.46856 0.945 NA NA NA NA 0.79011 1 1 1 3q gain 60 (11%) 468 0.1347 0.548 0.78833 1 0.00046 0.0138 0.00016 0.00768 0.0046908 0.0634 0.0060954 0.076 0.56769 1 0.9176 1 NA NA NA NA 0.4671 0.944 1 1 4p gain 13 (2%) 515 0.1398 0.56 0.77421 1 0.38458 0.884 0.1693 0.63 0.47369 0.951 1 1 0.39571 0.885 NA NA NA NA NA NA 1 1 1 1 4q gain 13 (2%) 515 0.37202 0.884 0.77421 1 0.45901 0.937 0.6775 1 0.4341 0.918 0.70242 1 0.77889 1 NA NA NA NA NA NA 1 1 1 1 5p gain 191 (36%) 337 0.075192 0.406 0.00024142 0.00998 0.098899 0.47 0.21477 0.697 0.79766 1 0.89868 1 0.023253 0.196 0.59568 1 NA NA NA NA 0.04027 0.28 0.8317 1 5q gain 210 (40%) 318 0.061584 0.368 0.00063975 0.0175 0.42014 0.899 0.39816 0.885 0.62088 1 1 1 0.01594 0.152 0.52297 1 0.58829 1 0.40373 0.885 0.04857 0.315 0.83641 1 6p gain 11 (2%) 517 0.93099 1 0.79315 1 0.3131 0.808 0.23135 0.709 1 1 0.68643 1 0.34245 0.845 NA NA NA NA NA NA 1 1 1 1 6q gain 9 (2%) 519 0.72795 1 0.35877 0.87 0.2036 0.681 0.28141 0.774 1 1 1 1 0.16751 0.627 NA NA NA NA NA NA 1 1 1 1 7p gain 173 (33%) 355 0.99306 1 0.24743 0.729 0.03913 0.274 0.064059 0.368 0.43235 0.918 0.025878 0.212 0.00379 0.0543 0.54134 1 0.097856 0.468 0.063525 0.368 0.085129 0.436 0.51168 0.993 7q gain 173 (33%) 355 0.51729 0.997 0.26871 0.76 0.0087399 0.102 0.03734 0.268 0.30073 0.803 0.002551 0.0422 0.0089018 0.102 0.3095 0.807 0.15437 0.6 0.063525 0.368 0.04449 0.303 0.27035 0.76 8p gain 31 (6%) 497 0.54985 1 0.17625 0.648 0.00087999 0.0203 0.00078999 0.019 1 1 0.19399 0.674 0.56281 1 0.22478 0.699 NA NA NA NA 0.52799 1 0.38167 0.884 8q gain 61 (12%) 467 0.14571 0.573 0.011701 0.125 0.0079999 0.096 0.00361 0.0534 0.41565 0.893 0.17659 0.648 0.20162 0.677 0.52308 1 0.79995 1 NA NA 0.85914 1 0.4942 0.974 9p gain 14 (3%) 514 0.11771 0.511 0.49272 0.973 0.89006 1 0.058749 0.355 1 1 0.14116 0.56 0.0084168 0.0998 NA NA NA NA NA NA 0.72401 1 0.58238 1 9q gain 13 (2%) 515 0.46058 0.937 0.22478 0.699 0.27547 0.771 0.00313 0.0493 1 1 1 1 0.075104 0.406 NA NA NA NA NA NA 1 1 0.58238 1 10p gain 16 (3%) 512 0.94857 1 0.18349 0.662 0.36572 0.881 0.18628 0.667 0.074233 0.406 0.72639 1 0.79638 1 0.87359 1 NA NA NA NA 0.40564 0.885 1 1 10q gain 12 (2%) 516 0.83982 1 0.015156 0.147 0.8476 1 0.87964 1 0.24594 0.726 1 1 0.36371 0.88 0.59922 1 NA NA NA NA 0.48583 0.964 1 1 11p gain 31 (6%) 497 0.53096 1 0.98642 1 0.02855 0.225 0.01281 0.131 1 1 0.11563 0.509 0.84717 1 0.3052 0.803 NA NA NA NA 0.73244 1 1 1 11q gain 29 (5%) 499 0.19888 0.676 0.94647 1 0.16163 0.615 0.083989 0.436 1 1 0.42041 0.899 1 1 NA NA NA NA NA NA 0.85102 1 1 1 12p gain 121 (23%) 407 0.0070312 0.0865 0.18548 0.667 0.00021 0.00916 0.00142 0.0273 0.047938 0.315 0.019331 0.17 0.38829 0.885 0.014828 0.145 0.31076 0.807 NA NA 0.10953 0.503 0.22463 0.699 12q gain 122 (23%) 406 0.010578 0.115 0.33433 0.834 2e-04 0.00914 0.00072999 0.0185 0.047938 0.315 0.019907 0.174 0.33408 0.834 0.014828 0.145 0.31076 0.807 NA NA 0.11062 0.503 0.22496 0.699 13q gain 22 (4%) 506 0.13379 0.548 0.25386 0.736 0.13057 0.543 0.20479 0.683 1 1 0.367 0.881 0.25703 0.741 NA NA NA NA NA NA 0.095739 0.464 0.089971 0.451 14q gain 16 (3%) 512 0.12357 0.525 0.47276 0.951 0.22675 0.7 0.0056599 0.0734 1 1 0.29538 0.798 0.79638 1 NA NA NA NA NA NA 1 1 1 1 15q gain 26 (5%) 502 0.50253 0.985 0.45056 0.937 0.45577 0.937 0.36835 0.882 0.19079 0.668 0.58245 1 0.67795 1 0.049928 0.32 NA NA NA NA 0.56074 1 1 1 16p gain 107 (20%) 421 0.37898 0.884 0.24507 0.726 0.19526 0.674 0.070549 0.398 0.21028 0.691 0.6482 1 0.65226 1 0.74218 1 0.064066 0.368 NA NA 0.2379 0.718 1 1 16q gain 99 (19%) 429 0.25213 0.734 0.33756 0.838 0.28601 0.781 0.04849 0.315 0.20761 0.687 1 1 1 1 0.64924 1 0.064066 0.368 NA NA 0.4226 0.902 0.78651 1 17p gain 26 (5%) 502 0.8342 1 0.55653 1 0.30298 0.803 0.8251 1 0.19079 0.668 0.021348 0.185 1 1 0.64578 1 NA NA NA NA 0.02693 0.217 0.61214 1 17q gain 33 (6%) 495 0.49151 0.973 0.3408 0.843 0.68726 1 0.66062 1 0.29603 0.798 0.20173 0.677 0.70872 1 0.52308 1 0.38892 0.885 NA NA 0.062359 0.368 0.38296 0.884 18p gain 25 (5%) 503 0.062397 0.368 0.80437 1 0.92693 1 0.87008 1 0.60745 1 0.40054 0.885 0.090714 0.451 NA NA NA NA NA NA 0.66516 1 0.33159 0.832 18q gain 25 (5%) 503 0.13836 0.56 0.617 1 0.82027 1 0.76836 1 0.57739 1 0.40054 0.885 0.090714 0.451 NA NA NA NA NA NA 0.66814 1 0.33159 0.832 19p gain 51 (10%) 477 0.76144 1 0.67585 1 0.00338 0.0523 0.01323 0.134 0.23227 0.709 0.0078085 0.0949 0.22043 0.699 0.45604 0.937 NA NA NA NA 0.071039 0.399 0.72705 1 19q gain 57 (11%) 471 0.82633 1 0.39151 0.885 0.00074999 0.0185 0.00468 0.0634 0.41565 0.893 0.0035373 0.0534 0.24205 0.722 0.45604 0.937 NA NA NA NA 0.0319 0.241 1 1 20p gain 112 (21%) 416 0.16198 0.615 0.23315 0.709 2e-05 0.0016 9.9999e-06 0.0016 0.37526 0.884 0.016733 0.154 0.00035011 0.0112 0.99136 1 0.49811 0.978 NA NA 0.32946 0.832 0.44155 0.928 20q gain 115 (22%) 413 0.1202 0.513 0.078741 0.42 5.9999e-05 0.00384 2e-05 0.0016 0.22464 0.699 0.018794 0.169 0.0019901 0.036 0.99136 1 0.49811 0.978 NA NA 0.31559 0.812 0.31927 0.819 21q gain 50 (9%) 478 0.71288 1 0.11614 0.509 0.22095 0.699 0.11064 0.503 1 1 0.53333 1 0.43919 0.925 0.12602 0.533 0.47799 0.954 NA NA 0.22025 0.699 0.71881 1 22q gain 40 (8%) 488 0.38254 0.884 0.56285 1 0.70011 1 0.087349 0.444 1 1 0.82026 1 0.30498 0.803 0.40727 0.885 NA NA NA NA 0.21331 0.694 1 1 xp gain 32 (6%) 496 0.57783 1 0.55751 1 0.02526 0.209 0.092789 0.454 1 1 0.036873 0.266 0.85052 1 0.58708 1 NA NA NA NA 0.10782 0.498 0.38296 0.884 xq gain 31 (6%) 497 0.92776 1 0.78062 1 0.053819 0.34 0.11678 0.51 1 1 0.027381 0.219 0.7045 1 0.33089 0.832 NA NA NA NA 0.5319 1 0.38296 0.884 1p loss 60 (11%) 468 0.529 1 0.30313 0.803 0.30478 0.803 0.01635 0.152 1 1 0.56429 1 0.25236 0.734 0.76437 1 NA NA NA NA 0.61493 1 0.11171 0.506 1q loss 37 (7%) 491 0.65075 1 0.53678 1 0.83412 1 0.073179 0.404 1 1 0.2428 0.722 0.72477 1 0.79087 1 NA NA NA NA 0.58437 1 0.46261 0.939 2p loss 14 (3%) 514 0.82815 1 0.83855 1 0.44456 0.93 0.13876 0.56 1 1 0.70745 1 0.77894 1 NA NA NA NA NA NA 0.055229 0.344 1 1 2q loss 14 (3%) 514 0.81657 1 0.81429 1 0.53892 1 0.22265 0.699 1 1 0.70745 1 0.77894 1 NA NA NA NA NA NA 0.17467 0.647 1 1 3p loss 379 (72%) 149 0.55903 1 0.79249 1 0.04333 0.297 0.0288 0.225 0.59293 1 0.10253 0.48 0.011802 0.125 0.32039 0.819 0.52246 1 0.45797 0.937 0.21922 0.699 0.65474 1 3q loss 102 (19%) 426 0.9895 1 0.012484 0.129 0.75692 1 0.37043 0.884 0.32158 0.819 1 1 0.00033345 0.0112 0.17969 0.652 NA NA NA NA 0.62983 1 0.78855 1 4p loss 72 (14%) 456 7.8031e-05 0.00468 0.74282 1 0.00026 0.00998 0.00013 0.00657 0.71839 1 0.021626 0.185 0.89524 1 0.92901 1 NA NA NA NA 0.0458 0.307 0.39895 0.885 4q loss 65 (12%) 463 6.83e-06 0.0016 0.82834 1 2e-05 0.0016 2e-05 0.0016 0.43751 0.923 0.0029309 0.0469 0.27043 0.76 0.87687 1 NA NA NA NA 0.02182 0.185 0.55006 1 5p loss 8 (2%) 520 0.010865 0.117 0.41337 0.893 0.01216 0.127 0.00102 0.0218 1 1 0.11609 0.509 0.46542 0.943 0.57143 1 NA NA NA NA 1 1 1 1 5q loss 7 (1%) 521 0.031358 0.239 0.28809 0.783 0.02757 0.219 0.00231 0.0397 1 1 0.30359 0.803 0.70496 1 0.57143 1 NA NA NA NA 1 1 1 1 6p loss 100 (19%) 428 0.42619 0.907 0.27068 0.76 0.03478 0.259 0.01838 0.168 0.015588 0.15 0.27926 0.773 0.0011779 0.0241 0.099757 0.471 0.50999 0.993 0.64274 1 0.03528 0.261 1 1 6q loss 128 (24%) 400 0.38493 0.884 0.66581 1 0.2788 0.773 0.17876 0.652 0.0036258 0.0534 0.66875 1 0.071656 0.4 0.44364 0.93 0.033704 0.253 0.64274 1 0.070049 0.398 0.47605 0.952 8p loss 137 (26%) 391 0.1891 0.668 0.67413 1 0.32949 0.832 0.1896 0.668 1 1 0.26684 0.758 0.038857 0.274 0.78018 1 0.96398 1 0.45797 0.937 0.13031 0.543 0.055893 0.345 8q loss 65 (12%) 463 0.50541 0.986 0.45868 0.937 0.56963 1 0.15881 0.61 1 1 1 1 0.0053613 0.0705 0.98825 1 NA NA NA NA 0.1994 0.676 0.056009 0.345 9p loss 149 (28%) 379 1.6778e-05 0.0016 0.057341 0.348 9.9999e-06 0.0016 5.9999e-05 0.00384 0.085377 0.436 0.0016012 0.0301 0.00088656 0.0203 0.61251 1 1 1 0.87234 1 0.13321 0.548 0.65544 1 9q loss 151 (29%) 377 0.0003454 0.0112 0.056487 0.345 9.9999e-06 0.0016 9.9999e-06 0.0016 0.09412 0.459 0.0042452 0.0598 0.001283 0.0251 0.39213 0.885 1 1 0.87234 1 0.12028 0.513 0.8227 1 10p loss 68 (13%) 460 0.29927 0.803 0.26521 0.756 0.079919 0.42 0.01037 0.114 0.14166 0.56 0.58584 1 0.279 0.773 0.16317 0.617 NA NA NA NA 0.551 1 0.20927 0.69 10q loss 89 (17%) 439 0.55512 1 0.5363 1 0.098049 0.468 0.00233 0.0397 0.4848 0.964 0.62659 1 0.11478 0.509 0.2123 0.694 NA NA NA NA 0.28461 0.781 0.27762 0.773 11p loss 18 (3%) 510 0.0036741 0.0534 0.0538 0.34 0.28626 0.781 0.40377 0.885 0.14093 0.56 0.50451 0.986 1 1 0.76175 1 NA NA NA NA 1 1 1 1 11q loss 23 (4%) 505 0.0023586 0.0397 0.0059043 0.0751 0.4567 0.937 0.51197 0.993 0.21667 0.697 0.38498 0.884 0.37983 0.884 0.35795 0.87 NA NA NA NA 0.64332 1 1 1 12p loss 4 (1%) 524 0.26058 0.745 0.68993 1 0.77308 1 1 1 1 1 1 1 0.62009 1 NA NA NA NA NA NA 0.40848 0.885 1 1 12q loss 4 (1%) 524 0.83628 1 0.31222 0.808 0.15991 0.612 0.40669 0.885 1 1 1 1 1 1 NA NA NA NA NA NA 1 1 1 1 13q loss 70 (13%) 458 0.00096671 0.0216 0.81206 1 0.00012 0.00657 2e-05 0.0016 0.2894 0.785 0.030864 0.237 0.34873 0.854 0.92901 1 NA NA NA NA 0.24103 0.722 0.22639 0.7 14q loss 216 (41%) 312 0.00073822 0.0185 0.25666 0.741 9.9999e-06 0.0016 0.00013 0.00657 0.00072406 0.0185 0.0011057 0.0231 0.026646 0.217 0.036249 0.266 0.20118 0.677 0.073025 0.404 0.01899 0.169 0.68602 1 15q loss 35 (7%) 493 0.0017229 0.0318 0.989 1 0.00053999 0.0157 0.00033 0.0112 1 1 0.014226 0.142 0.045788 0.307 0.94906 1 NA NA NA NA 0.03682 0.266 0.38229 0.884 16p loss 10 (2%) 518 0.088147 0.445 0.65204 1 0.39472 0.885 0.01636 0.152 0.34636 0.853 1 1 1 1 NA NA NA NA NA NA 0.40282 0.885 1 1 16q loss 16 (3%) 512 0.13455 0.548 0.33213 0.832 0.41411 0.893 0.0050799 0.0677 0.4341 0.918 1 1 0.79638 1 NA NA NA NA NA NA 0.16637 0.626 1 1 17p loss 46 (9%) 482 0.40046 0.885 0.30014 0.803 0.14093 0.56 0.13206 0.546 0.37479 0.884 0.047395 0.315 0.19735 0.674 0.32099 0.819 NA NA NA NA 1 1 0.71264 1 17q loss 28 (5%) 500 0.45871 0.937 0.7868 1 0.30821 0.807 0.26062 0.745 1 1 0.17989 0.652 0.31088 0.807 NA NA NA NA NA NA 0.84257 1 1 1 18p loss 93 (18%) 435 0.001009 0.0218 0.092677 0.454 0.00031 0.0112 0.00025 0.00998 1 1 0.079678 0.42 0.23412 0.709 0.86863 1 NA NA NA NA 0.23372 0.709 0.097785 0.468 18q loss 95 (18%) 433 0.0059483 0.0751 0.11334 0.508 0.0088899 0.102 0.0043 0.0598 1 1 0.11279 0.508 0.1934 0.674 0.81453 1 NA NA NA NA 0.21256 0.694 0.28021 0.773 19p loss 11 (2%) 517 2.7795e-05 0.00205 0.09268 0.454 0.02454 0.205 0.00059999 0.0169 1 1 0.39125 0.885 0.75375 1 NA NA NA NA NA NA 0.12022 0.513 1 1 19q loss 4 (1%) 524 0.0023462 0.0397 0.84447 1 0.19438 0.674 0.00273 0.0444 1 1 0.11838 0.512 1 1 NA NA NA NA NA NA 1 1 1 1 20p loss 8 (2%) 520 0.72387 1 0.70111 1 0.78975 1 0.61418 1 1 1 0.36609 0.881 1 1 NA NA NA NA NA NA 0.1565 0.604 0.2501 0.732 20q loss 3 (1%) 525 0.87846 1 0.11489 0.509 0.22952 0.706 0.10676 0.498 NA NA 0.40215 0.885 1 1 NA NA NA NA NA NA 1 1 0.069149 0.395 21q loss 55 (10%) 473 0.69707 1 0.72314 1 0.076419 0.41 0.00126 0.0251 0.084408 0.436 1 1 0.46085 0.937 0.80443 1 NA NA NA NA 0.58154 1 1 1 22q loss 39 (7%) 489 0.0090044 0.102 0.24236 0.722 0.01897 0.169 0.15662 0.604 1 1 0.10007 0.471 0.86262 1 0.91098 1 NA NA NA NA 1 1 0.0095931 0.107 xp loss 45 (9%) 483 0.25021 0.732 0.89815 1 0.95055 1 0.51498 0.995 0.21667 0.697 0.82269 1 0.19736 0.674 0.37674 0.884 NA NA NA NA 0.80912 1 0.14923 0.585 xq loss 45 (9%) 483 0.18754 0.668 0.67311 1 0.95039 1 0.51473 0.995 0.24294 0.722 1 1 0.19736 0.674 0.71599 1 NA NA NA NA 0.58493 1 0.15002 0.585