Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.483 0.258 0.616 415.0 -9999.0 0.0 415.0 KIRREL -0.056 0.108 -9999.0 0.0 -0.808 10.0 10.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.484 0.258 -9999.0 0.0 -0.617 415.0 415.0 PLCG1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.038 -9999.0 0.0 -0.863 1.0 1.0 WASL 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.525 0.307 -9999.0 0.0 -0.834 230.0 230.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.406 0.259 -9999.0 0.0 -0.661 230.0 230.0 FYN -0.494 0.298 -9999.0 0.0 -0.79 231.0 231.0 mol:Ca2+ -0.518 0.302 -9999.0 0.0 -0.821 230.0 230.0 mol:DAG -0.521 0.304 -9999.0 0.0 -0.827 230.0 230.0 NPHS2 -0.405 0.38 -9999.0 0.0 -0.803 254.0 254.0 mol:IP3 -0.521 0.304 -9999.0 0.0 -0.827 230.0 230.0 regulation of endocytosis -0.465 0.275 -9999.0 0.0 -0.743 230.0 230.0 Nephrin/NEPH1/podocin/Cholesterol -0.534 0.31 -9999.0 0.0 -0.644 442.0 442.0 establishment of cell polarity -0.483 0.258 -9999.0 0.0 -0.616 415.0 415.0 Nephrin/NEPH1/podocin/NCK1-2 -0.484 0.289 -9999.0 0.0 -0.778 230.0 230.0 Nephrin/NEPH1/beta Arrestin2 -0.473 0.282 -9999.0 0.0 -0.759 230.0 230.0 NPHS1 -0.605 0.324 -9999.0 0.0 -0.78 412.0 412.0 Nephrin/NEPH1/podocin -0.502 0.294 -9999.0 0.0 -0.797 231.0 231.0 TJP1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.014 0.033 -9999.0 0.0 -0.742 1.0 1.0 NCK2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.525 0.307 -9999.0 0.0 -0.834 230.0 230.0 CD2AP 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.525 0.307 -9999.0 0.0 -0.832 231.0 231.0 GRB2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.485 0.299 -9999.0 0.0 -0.783 230.0 230.0 cytoskeleton organization -0.524 0.316 -9999.0 0.0 -0.841 230.0 230.0 Nephrin/NEPH1 -0.362 0.197 -9999.0 0.0 -0.461 415.0 415.0 Nephrin/NEPH1/ZO-1 -0.392 0.214 -9999.0 0.0 -0.501 415.0 415.0