Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.395 0.231 0.524 392.0 -9999.0 0.0 392.0 KIRREL -0.06 0.087 -9999.0 0.0 -0.626 9.0 9.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.396 0.232 -9999.0 0.0 -0.525 392.0 392.0 PLCG1 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.028 0.032 -9999.0 0.0 -0.707 1.0 1.0 WASL 0.027 0.009 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.415 0.279 -9999.0 0.0 -0.536 413.0 413.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.34 0.235 -9999.0 0.0 -0.463 369.0 369.0 FYN -0.398 0.254 0.265 1.0 -0.504 417.0 418.0 mol:Ca2+ -0.406 0.276 -9999.0 0.0 -0.531 406.0 406.0 mol:DAG -0.409 0.278 -9999.0 0.0 -0.534 406.0 406.0 NPHS2 -0.337 0.326 -9999.0 0.0 -0.688 241.0 241.0 mol:IP3 -0.409 0.278 -9999.0 0.0 -0.534 406.0 406.0 regulation of endocytosis -0.371 0.249 -9999.0 0.0 -0.486 394.0 394.0 Nephrin/NEPH1/podocin/Cholesterol -0.421 0.276 -9999.0 0.0 -0.537 417.0 417.0 establishment of cell polarity -0.395 0.231 -9999.0 0.0 -0.524 392.0 392.0 Nephrin/NEPH1/podocin/NCK1-2 -0.378 0.268 -9999.0 0.0 -0.646 216.0 216.0 Nephrin/NEPH1/beta Arrestin2 -0.376 0.253 -9999.0 0.0 -0.494 394.0 394.0 NPHS1 -0.513 0.283 -9999.0 0.0 -0.666 404.0 404.0 Nephrin/NEPH1/podocin -0.397 0.263 -9999.0 0.0 -0.507 417.0 417.0 TJP1 0.03 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.03 -9999.0 0.0 -0.635 1.0 1.0 NCK2 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.411 0.28 -9999.0 0.0 -0.537 406.0 406.0 CD2AP 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.413 0.28 -9999.0 0.0 -0.536 411.0 411.0 GRB2 0.029 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.39 0.255 0.276 1.0 -0.5 408.0 409.0 cytoskeleton organization -0.43 0.284 -9999.0 0.0 -0.58 369.0 369.0 Nephrin/NEPH1 -0.288 0.173 -9999.0 0.0 -0.384 392.0 392.0 Nephrin/NEPH1/ZO-1 -0.316 0.199 -9999.0 0.0 -0.428 390.0 390.0