Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.484 0.354 0.715 195.0 -9999.0 0.0 195.0 KIRREL -0.121 0.243 -9999.0 0.0 -0.869 27.0 27.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.486 0.355 -9999.0 0.0 -0.717 195.0 195.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.011 0.018 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.523 0.376 -9999.0 0.0 -0.702 216.0 216.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.397 0.309 -9999.0 0.0 -0.542 216.0 216.0 FYN -0.491 0.361 -9999.0 0.0 -0.664 216.0 216.0 mol:Ca2+ -0.515 0.368 -9999.0 0.0 -0.691 216.0 216.0 mol:DAG -0.519 0.371 -9999.0 0.0 -0.697 216.0 216.0 NPHS2 -0.354 0.401 -9999.0 0.0 -0.868 109.0 109.0 mol:IP3 -0.519 0.371 -9999.0 0.0 -0.697 216.0 216.0 regulation of endocytosis -0.459 0.342 -9999.0 0.0 -0.623 216.0 216.0 Nephrin/NEPH1/podocin/Cholesterol -0.528 0.378 -9999.0 0.0 -0.709 216.0 216.0 establishment of cell polarity -0.484 0.354 -9999.0 0.0 -0.715 195.0 195.0 Nephrin/NEPH1/podocin/NCK1-2 -0.486 0.354 -9999.0 0.0 -0.653 216.0 216.0 Nephrin/NEPH1/beta Arrestin2 -0.468 0.351 -9999.0 0.0 -0.636 216.0 216.0 NPHS1 -0.553 0.399 -9999.0 0.0 -0.848 187.0 187.0 Nephrin/NEPH1/podocin -0.496 0.365 -9999.0 0.0 -0.67 216.0 216.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.523 0.376 -9999.0 0.0 -0.702 216.0 216.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.523 0.376 -9999.0 0.0 -0.702 216.0 216.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.601 0.399 -9999.0 0.0 -0.746 235.0 235.0 cytoskeleton organization -0.515 0.389 -9999.0 0.0 -0.703 216.0 216.0 Nephrin/NEPH1 -0.371 0.28 -9999.0 0.0 -0.55 195.0 195.0 Nephrin/NEPH1/ZO-1 -0.406 0.3 -9999.0 0.0 -0.598 195.0 195.0