Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.045 0.202 0.67 33.0 -9999.0 0.0 33.0 KIRREL -0.074 0.247 0.323 2.0 -0.862 33.0 35.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.045 0.203 -9999.0 0.0 -0.672 33.0 33.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.032 0.16 -9999.0 0.0 -0.517 33.0 33.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.026 0.123 -9999.0 0.0 -0.406 29.0 29.0 FYN -0.039 0.142 -9999.0 0.0 -0.488 33.0 33.0 mol:Ca2+ -0.032 0.158 -9999.0 0.0 -0.512 33.0 33.0 mol:DAG -0.032 0.159 -9999.0 0.0 -0.515 33.0 33.0 NPHS2 -0.0 0.043 0.314 5.0 -9999.0 0.0 5.0 mol:IP3 -0.032 0.159 -9999.0 0.0 -0.515 33.0 33.0 regulation of endocytosis -0.028 0.141 -9999.0 0.0 -0.457 33.0 33.0 Nephrin/NEPH1/podocin/Cholesterol -0.033 0.161 -9999.0 0.0 -0.524 33.0 33.0 establishment of cell polarity -0.045 0.202 -9999.0 0.0 -0.67 33.0 33.0 Nephrin/NEPH1/podocin/NCK1-2 -0.029 0.154 -9999.0 0.0 -0.489 33.0 33.0 Nephrin/NEPH1/beta Arrestin2 -0.028 0.143 -9999.0 0.0 -0.463 33.0 33.0 NPHS1 0.017 0.083 0.318 25.0 -9999.0 0.0 25.0 Nephrin/NEPH1/podocin -0.03 0.152 -9999.0 0.0 -0.491 33.0 33.0 TJP1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 -0.001 0.048 0.316 1.0 -0.86 1.0 2.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.032 0.16 -9999.0 0.0 -0.517 33.0 33.0 CD2AP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.032 0.16 -9999.0 0.0 -0.517 33.0 33.0 GRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.018 0.156 -9999.0 0.0 -0.476 33.0 33.0 cytoskeleton organization -0.035 0.15 -9999.0 0.0 -0.504 30.0 30.0 Nephrin/NEPH1 -0.033 0.155 -9999.0 0.0 -0.508 33.0 33.0 Nephrin/NEPH1/ZO-1 -0.037 0.169 -9999.0 0.0 -0.555 33.0 33.0