Hybridization REF	p	difference	q	subclass
Composite Element REF	p	difference	q	subclass
MYH11|MYH11	0.000435408146851733	0.621079800687013	0.00109602740414402	1
BRD4|BRD4	2.34964162465549e-06	0.566145859279221	1.00896375646971e-05	1
SYK|SYK	5.05530079818521e-06	0.554835479085281	1.97698370500457e-05	1
BCL2L1|BCL-XL	6.21366440044122e-11	0.486824468649784	9.07195002464418e-10	1
BAX|BAX	3.24416500494901e-08	0.439894850399567	2.73258513878397e-07	1
MAPK1|ERK2	5.62952705866679e-11	0.43326904988961	8.89458125357621e-10	1
BCL2A1|BCL2A1	5.20940898744347e-08	0.428109149933766	3.93400195948317e-07	1
PEA15|PEA15	1.45368240148107e-08	0.420842104740693	1.38415846054067e-07	1
CAV1|CAVEOLIN-1	0.000124898333981308	0.418393631093939	0.000346237153695018	1
YWHAZ|14-3-3_ZETA	1.28020353506961e-05	0.398033697024675	4.59614056033188e-05	1
XRCC5|KU80	9.35927150465306e-07	0.387476226308658	4.76669874306749e-06	1
HSPA1A|HSP70	7.63074962181764e-05	0.377712501026407	0.00022499748092597	1
SERPINE1|PAI-1	0.0298593785368438	0.364804074288745	0.0474648698179539	1
MAPK14|P38_MAPK	2.34784784997656e-07	0.359047236139827	1.4690819404139e-06	1
COL6A1|COLLAGEN_VI	8.70328590126557e-06	0.356751088805628	3.2862407109951e-05	1
CHEK1|CHK1_PS296	1.26785163850296e-09	0.347853524235065	1.6332912284244e-08	1
PDCD4|PDCD4	1.44358401042663e-06	0.34782409708355	6.75451105294986e-06	1
BRAF|B-RAF_PS445	1.52873016145312e-06	0.347532974606493	6.97483136162986e-06	1
PEA15|PEA15_PS116	0.0116449024445338	0.344061695041125	0.020733606791487	1
TIGAR|TIGAR	0.000261507006045401	0.33783455899697	0.00069000041354148	1
YAP1|YAP_PS127	1.00553984917576e-05	0.337513836204762	3.73242757575409e-05	1
ATM|ATM	0.00124186616130308	0.330721772185714	0.00277519070740178	1
LCK|LCK	6.50660714228451e-07	0.32398133694329	3.39273086704835e-06	1
PRKAA1|AMPK_PT172	0.0122817624539345	0.323335775796104	0.0216911772371908	1
SMAD3|SMAD3	5.04814946328212e-12	0.320411140434199	1.00504066587162e-10	1
FN1|FIBRONECTIN	0.00984001886955442	0.306679280208225	0.0178096209291935	1
PIK3R1 PIK3R2|PI3K-P85	1.55948768779136e-07	0.295703013344156	1.00449354007738e-06	1
CDKN2A|P16_INK4A	0.00800754023954173	0.293785919951082	0.0147365656509213	1
ABL1|C-ABL	7.23198463313757e-13	0.292320655942424	1.75978292739681e-11	1
PRKAA1|AMPK_ALPHA	2.3916212798834e-05	0.288796225466234	8.44782355313653e-05	1
ARAF|A-RAF	1.44959826250522e-06	0.286571045009957	6.75451105294986e-06	1
GSK3A GSK3B|GSK3-ALPHA-BETA	2.18501136673451e-06	0.284669352164935	9.57034978629715e-06	1
EIF4EBP1|4E-BP1_PT37_T46	0.0014977004716032	0.28427901505671	0.00324748914139704	1
BID|BID	3.7954335292795e-07	0.280059641345022	2.1312819049031e-06	1
GAPDH|GAPDH	0.032903579456869	0.275920695911255	0.0503907965108693	1
TSC1|TSC1	1.20643855893185e-06	0.274538912745887	5.871334320135e-06	1
KDR|VEGFR2	0.000268677777229413	0.273100393165801	0.000692240390744017	1
ARID1A|ARID1A	0.00144105099345362	0.264368168898268	0.00315590167566343	1
IRF1|IRF-1	2.79285447888073e-07	0.260203168183983	1.65306792128346e-06	1
MAP2K1|MEK1	0.00290997171026093	0.254477210898268	0.00590077596802911	1
RICTOR|RICTOR_PT1135	6.0699478680896e-08	0.25345694565671	4.43106194370541e-07	1
CCND1|CYCLIN_D1	0.00116443582290291	0.250786681785714	0.00271288771506104	1
EIF4EBP1|4E-BP1_PT70	0.00037563946700135	0.242745130341558	0.000956570270619717	1
RAF1|C-RAF	3.41372288183758e-05	0.242485611951948	0.000111582882257079	1
STK11|LKB1	2.53133724363991e-08	0.238736708192641	2.21745142542856e-07	1
EIF4EBP1|4E-BP1_PS65	1.44340828116435e-07	0.235892929195238	9.57898222954523e-07	1
PXN|PAXILLIN	0.00121998376930254	0.235177473324242	0.00275439634512635	1
CASP7|CASPASE-7_CLEAVEDD198	0.00755643213408888	0.23426985720303	0.0140242257403853	1
YBX1|YB-1	0.0129231586717454	0.229530521740693	0.0222848169221436	1
PDK1|PDK1_PS241	3.13224359104128e-05	0.228740107886147	0.000103933537339097	1
NF2|NF2	4.48153556620791e-05	0.22406769582987	0.000140208041285647	1
RAB11A RAB11B|RAB11	3.26021883309217e-06	0.216068601887879	1.34714702725884e-05	1
GAB2|GAB2	0.00417194214321051	0.206838884001299	0.00823112909336128	1
SRC|SRC	0.000540045303875266	0.205935780592641	0.00129966946756795	1
STAT5A|STAT5-ALPHA	0.0306179845134948	0.202472444665368	0.0482398461039954	1
CLDN7|CLAUDIN-7	0.0326203294370939	0.200888566287013	0.0503907965108693	1
ERCC5|ERCC5	0.0124398458108904	0.193743183783117	0.0216923169504216	1
YAP1|YAP	0.000120274755509147	0.188734357137229	0.000342080148785756	1
COG3|COG3	0.0310382396122654	0.1798036545	0.0485526748220437	1
RPTOR|RAPTOR	0.000177231436617062	0.169333370703463	0.000485171057739207	1
ERBB3|HER3_PY1289	2.60240732385506e-05	0.163411227402165	8.90511256131653e-05	1
ANXA7|ANNEXIN_VII	0.00361779004027954	0.158485873333766	0.00726877081487357	1
RPS6|S6	0.0124805111221604	0.157483435611688	0.0216923169504216	1
TP53BP1|53BP1	0.0163516275659702	0.156318214779654	0.027335926999599	1
SMAD1|SMAD1	0.000124876932957139	0.155943991151948	0.000346237153695018	1
EEF2|EEF2	0.0161267456901772	0.155872316592641	0.0271673638934524	1
EIF4EBP1|4E-BP1	0.00606356988000466	0.154551659384848	0.0116484368747458	1
BCL2L11|BIM	0.0368140076686578	0.148672999034199	0.0559879699960837	1
PDK1|PDK1	2.53204489919566e-05	0.141812095330303	8.80187036387063e-05	1
CASP8|CASPASE-8	0.000224318895267066	0.122775070341558	0.000599095586140091	1
CHEK2|CHK2_PT68	0.00731513761433282	0.111796849755411	0.0136924370729819	1
MAP2K1|MEK1_PS217_S221	0.00943738168562842	0.107588369280087	0.0172232215762719	1
YBX1|YB-1_PS102	0.000494553861065587	0.0921714434099567	0.00121693590531869	1
CDKN1B|P27_PT157	0.00118307892934507	0.090673425291342	0.00272730826870074	1
WWTR1|TAZ	0.019956598193895	0.0838147917354978	0.0331098106398712	1
BAD|BAD_PS112	0.039798429057894	0.0724995013536797	0.0601093514736468	1
BIRC2 |CIAP	0.0492507823853498	0.0659535353424242	0.0738761735780247	1
EGFR|EGFR_PY1173	0.0255719754843487	0.0492171021952381	0.0414834268968323	1
CDK1|CDK1	0.0274341469661797	-0.0728550520220779	0.0441770454823041	1
RB1|RB	0.0149341094464566	-0.083118327304329	0.0253532555718914	1
NRG1|HEREGULIN	0.0326892102749614	-0.0960697968471861	0.0503907965108693	1
MAPK8|JNK_PT183_PY185	0.000578979483568245	-0.101193839009957	0.00137822290110267	1
BAK1|BAK	0.000445247127050736	-0.108939051358874	0.00110805819118308	1
MTOR|MTOR_PS2448	0.0202219171488429	-0.10909847244026	0.0331127026641049	1
CDKN1B|P27	0.00523721853922568	-0.110806486380519	0.0102406326793788	1
ITGA2|CD49B	0.020260740442877	-0.114366131485281	0.0331127026641049	1
CDK1|CDK1_PY15	0.00634828542705701	-0.115915423178788	0.0119851250734956	1
FOXO3|FOXO3A_PS318_S321	4.22277463832561e-05	-0.12514176324632	0.000135998183204898	1
CTNNA1|ALPHA-CATENIN	7.70539318239623e-05	-0.129307649048918	0.00022499748092597	1
BECN1|BECLIN	0.00387932614944152	-0.138419610198701	0.00772338569752448	1
ACVRL1|ACVRL1	0.00185655427066255	-0.138837662286147	0.00390947485841441	1
NRAS|N-RAS	2.58127938590099e-06	-0.149745218948485	1.08711574136984e-05	1
PREX1|PREX1	0.0147639634988571	-0.150560855145022	0.0252602187988258	1
BRCA2|BRCA2	7.19953187321098e-05	-0.150691671066234	0.000215985956196329	1
JUN|C-JUN_PS73	0.00176065827432583	-0.15190271960303	0.00374353555414909	1
SMAD4|SMAD4	6.33739481948271e-05	-0.154819090997836	0.000192762425759266	1
CHEK1|CHK1_PS345	8.67214880721367e-05	-0.154851235082684	0.000249894814313131	1
PRKCD|PKC-DELTA_PS664	3.83909294172281e-06	-0.156888120871429	1.55696547080981e-05	1
YWHAE|14-3-3_EPSILON	2.69928271532192e-07	-0.161761441500866	1.64206365182083e-06	1
RPS6KA1|P90RSK_PT359_S363	0.00212695163633572	-0.167583277443723	0.00435329353605161	1
XBP1|XBP1	0.0299093700222723	-0.172640117845455	0.0474648698179539	1
ERCC1|ERCC1	0.000268180208186567	-0.178517661248052	0.000692240390744017	1
EEF2K|EEF2K	0.00616669164770915	-0.190479561728571	0.0117435258334635	1
PGR|PR	4.45204160806464e-09	-0.199294862531169	5.41665062314531e-08	1
RAD51|RAD51	0.0116075004263576	-0.220179315004762	0.020733606791487	1
ANXA1|ANNEXIN-1	0.00169034477203334	-0.226586191852381	0.00362926965760099	1
BCL2|BCL-2	1.60759525895594e-06	-0.235698779261905	7.18496656553777e-06	1
SHC1|SHC_PY317	4.30958930569083e-05	-0.241027203045455	0.000136782617093665	1
ARAF|A-RAF_PS299	1.62386579825098e-11	-0.243901622288745	2.96355508180804e-10	1
GSK3A GSK3B|GSK3_PS9	0.00537255624118318	-0.244523937351082	0.010412299263886	1
RPS6KB1|P70S6K_PT389	1.14537864000172e-05	-0.253790405241991	4.18063203600628e-05	1
GUSP4|DUSP4	5.84560067482109e-06	-0.257260566671429	2.24594131190495e-05	1
NKX2-1|TTF1	9.65382119617041e-10	-0.263389288670563	1.32136677622582e-08	1
FOXM1|FOXM1	1.39134561151881e-07	-0.274572634996104	9.52202152883186e-07	1
PECAM1|CD31	3.3336598420192e-07	-0.28840627168961	1.92124080369001e-06	1
AR|AR	5.03079460095596e-07	-0.295911191768398	2.68718053075452e-06	1
TSC2|TUBERIN_PT1462	1.05728120644227e-06	-0.299783545825541	5.26237691388312e-06	1
PRDX1|PRDX1	0.000632379055850422	-0.309455015874026	0.00148915067990583	1
PARP1|PARP_CLEAVED	5.68603367808525e-11	-0.311661987505195	8.89458125357621e-10	1
INPP4B|INPP4B	5.16121770283028e-09	-0.31454587778658	5.94898251010438e-08	1
IGFBP2|IGFBP2	0.00199416739375428	-0.317734282957143	0.00415926342125893	1
PTPN11|SHP-2_PY542	4.41470531252085e-08	-0.333306100698268	3.45293022657881e-07	1
SNAI1|SNAIL	1.30056001045467e-13	-0.337399795859307	7.12056605723932e-12	1
BAP1|BAP1-C-4	4.74515521000868e-05	-0.337788582614286	0.000146364646618578	1
SRSF1|SF2	7.65438586554656e-08	-0.346140384132035	5.40745324049902e-07	1
RPS6|S6_PS235_S236	0.00133795011510352	-0.353964880225541	0.00295970783038051	1
CHEK1|CHK1	2.42559819867176e-08	-0.377878259925974	2.21335835628798e-07	1
SCD|SCD	6.02040195423837e-13	-0.392171699155411	1.75503255177877e-11	1
ACACA ACACB|ACC_PS79	0.000194392773438021	-0.40809244514329	0.000525580461517612	1
SRC|SRC_PY416	1.13838301545318e-08	-0.424646325637662	1.22441825493364e-07	1
EGFR|EGFR_PY1068	1.23000920586941e-08	-0.438705178287013	1.22441825493364e-07	1
ESR1|ER-ALPHA	1.18020825359135e-08	-0.449639344480087	1.22441825493364e-07	1
RB1|RB_PS807_S811	4.368465809173e-07	-0.452189980260173	2.39173503052222e-06	1
RPS6|S6_PS240_S244	0.00206586150661048	-0.456477937147619	0.00426814782969524	1
MET|C-MET	6.41107781471696e-13	-0.460991317117316	1.75503255177877e-11	1
AKT1 AKT2 AKT3|AKT_PS473	5.04006333027917e-06	-0.468695284946753	1.97698370500457e-05	1
EPPK1|EPPK1	0.00120073563580227	-0.474515841556277	0.00273917816917393	1
MSH2|MSH2	1.17076928490038e-13	-0.518379410118182	7.12056605723932e-12	1
FOXO3|FOXO3A	2.38855095776864e-13	-0.518973462904329	1.04618531950266e-11	1
SQSTM1|P62-LCK-LIGAND	0.000502920621863119	-0.523462728623809	0.00122377351320026	1
TP53|P53	3.81446995734028e-13	-0.561693299390909	1.3922815344292e-11	1
DIRAS3|DIRAS3	5.09358996702361e-15	-0.57254536705671	1.11549620277817e-12	1
COPS5|JAB1	3.46296856305494e-14	-0.57949559071645	3.79195057654516e-12	1
SETD2|SETD2	8.51602494312e-13	-0.60403041211039	1.86500946254328e-11	1
RAB25|RAB25	4.40347782261843e-08	-0.66409452061342	3.45293022657881e-07	1
FASN|FASN	2.69958240258062e-05	-0.763271455120779	9.09551609484855e-05	1
DIRAS3|DIRAS3	7.12773745835347e-27	0.53195846255974	7.80487251689705e-25	2
COPS5|JAB1	3.90312090791338e-26	0.527139013383117	1.42463913138838e-24	2
RAB25|RAB25	1.25786444534559e-05	0.525676762783117	2.18628820262448e-05	2
ESR1|ER-ALPHA	7.66662171293345e-17	0.518109962696537	3.64997859811397e-16	2
FOXO3|FOXO3A	3.10515790073284e-26	0.491592744795238	1.36005916052098e-24	2
TP53|P53	1.45639690318406e-24	0.479240399577922	2.92139695106281e-23	2
AKT1 AKT2 AKT3|AKT_PS473	5.41031043453261e-17	0.46426005311645	2.75548368642475e-16	2
MSH2|MSH2	1.46736833158406e-24	0.455020933893074	2.92139695106281e-23	2
SRC|SRC_PY416	4.19674240869223e-23	0.444729610049784	5.96095977319789e-22	2
SETD2|SETD2	4.48507086852824e-08	0.436592343625541	1.00227604102825e-07	2
EGFR|EGFR_PY1068	5.71487595982064e-20	0.418321311284416	5.00623134080288e-19	2
INPP4B|INPP4B	2.66466595739505e-26	0.380809535069697	1.36005916052098e-24	2
MET|C-MET	5.98923160553697e-22	0.378763874334632	7.71553953889763e-21	2
ANXA1|ANNEXIN-1	4.05079605086359e-20	0.3760466493	3.85706232669185e-19	2
MAPK1 MAPK3|MAPK_PT202_Y204	9.6814835793682e-13	0.352785334477489	3.31288266231506e-12	2
GUSP4|DUSP4	1.16581994575689e-26	0.352107563814286	8.5104856040253e-25	2
RAD51|RAD51	2.97194289251757e-17	0.350341442502597	1.54965593681273e-16	2
PTPN11|SHP-2_PY542	3.75163329064286e-24	0.348075630893939	6.84673075542322e-23	2
SNAI1|SNAIL	1.21354889460124e-27	0.340008903864502	2.65767207917672e-25	2
SRC|SRC_PY527	2.05628286875521e-08	0.324900515915584	4.79070157720629e-08	2
CHEK1|CHK1	2.26593304859002e-19	0.311370608961472	1.90861283708159e-18	2
PECAM1|CD31	5.60782269365574e-21	0.307055575417749	6.4637535258453e-20	2
BCL2|BCL-2	4.35503910370622e-23	0.306073825016017	5.96095977319789e-22	2
RB1|RB_PS807_S811	1.9972482068056e-10	0.301837972357143	5.9917446204168e-10	2
NKX2-1|TTF1	1.19512822945811e-24	0.29921220318658	2.90814535834807e-23	2
RPS6KB1|P70S6K_PT389	1.14885643945074e-20	0.294813615385714	1.19809314399863e-19	2
PARP1|PARP_CLEAVED	5.78331705467059e-24	0.294155048641126	9.74266488440661e-23	2
TSC2|TUBERIN_PT1462	5.89509359115821e-18	0.292016037487879	3.79713381312838e-17	2
SRSF1|SF2	1.53778140925583e-18	0.286467846121645	1.12258042875676e-17	2
ARAF|A-RAF_PS299	1.09954705153043e-23	0.271533789003896	1.72000574489403e-22	2
FOXM1|FOXM1	3.46664011522441e-20	0.261747183087879	3.45088266015521e-19	2
PREX1|PREX1	4.90562355750881e-14	0.255867939957143	1.8847922089376e-13	2
GSK3A GSK3B|GSK3_PS9	2.02385489718281e-09	0.251374202041991	5.09453129290845e-09	2
XBP1|XBP1	3.1112991744767e-09	0.226023138508658	7.65589347427413e-09	2
BECN1|BECLIN	3.95931238456764e-15	0.22408682775368	1.73417882444063e-14	2
RPS6KA1|P90RSK_PT359_S363	4.12493965072299e-18	0.220534479069697	2.79650973891045e-17	2
EPPK1|EPPK1	0.00603288924956326	0.213939099989177	0.00810553831689788	2
SCD|SCD	6.42343346762434e-11	0.200625942971861	2.0096170420139e-10	2
STAT3|STAT3_PY705	2.02010813662858e-09	0.198483874513853	5.09453129290845e-09	2
JUN|C-JUN_PS73	5.06829816558802e-14	0.198354216015152	1.91371947976513e-13	2
NDRG1|NDRG1_PT346	5.17496380094736e-05	0.194718371467965	8.45759009259307e-05	2
RPS6|S6_PS235_S236	0.000138643747961455	0.191893692651515	0.000213823808475765	2
PTEN|PTEN	5.76856122876327e-06	0.187340889047186	1.0527624242493e-05	2
BAP1|BAP1-C-4	3.50427587468876e-08	0.184599981140693	7.91171563460658e-08	2
PGR|PR	1.40498972264382e-18	0.179824664479221	1.06100948020344e-17	2
SHC1|SHC_PY317	2.74047149660375e-08	0.177546906541558	6.31750797638128e-08	2
SMAD4|SMAD4	1.42143172477061e-17	0.172252391896537	7.9818858390965e-17	2
AR|AR	0.000968090216345146	0.170832041287013	0.0014325118741864	2
BRCA2|BRCA2	4.21391878465958e-18	0.168830161952814	2.79650973891045e-17	2
YWHAE|14-3-3_EPSILON	7.87982526834973e-18	0.162873191871429	4.76345243126863e-17	2
PRKCD|PKC-DELTA_PS664	5.39216782472732e-15	0.15872606834329	2.27093221849093e-14	2
ACVRL1|ACVRL1	4.35976676159862e-10	0.157083902036797	1.20859357062038e-09	2
FOXO3|FOXO3A_PS318_S321	1.25291259916011e-14	0.156800499528571	5.17712941917102e-14	2
ITGA2|CD49B	1.67472422560964e-09	0.152586914676623	4.31487771068837e-09	2
CDK1|CDK1_PY15	2.19666650876552e-09	0.150960217528571	5.46670415249601e-09	2
BAK1|BAK	1.12439980404625e-15	0.138965198177922	5.2392246188538e-15	2
ERBB2|HER2_PY1248	5.91581656979655e-06	0.138261306163203	1.07071390808714e-05	2
PARP1|PARP1	7.87640258318607e-06	0.136197949349351	1.3864274113415e-05	2
CTNNA1|ALPHA-CATENIN	3.99030988502255e-12	0.132027239724242	1.3240573709393e-11	2
NRAS|N-RAS	2.41476513122229e-10	0.130678637512987	7.05111418316909e-10	2
NOTCH1|NOTCH1	2.62287147894625e-10	0.124978045921645	7.39668846787902e-10	2
MAPK8|JNK_PT183_PY185	1.60121500135794e-11	0.121135158634199	5.15685419554984e-11	2
MTOR|MTOR_PS2448	1.61990398096699e-06	0.118913538968398	3.11192080554185e-06	2
MAPK14|P38_PT180_Y182	0.00681945557600253	0.116523004912987	0.00905127740087609	2
ERCC1|ERCC1	3.17597238961121e-08	0.115527932190043	7.24518701380057e-08	2
PRDX1|PRDX1	0.00540105276257966	0.113205023998701	0.00734677363357109	2
YWHAB|14-3-3_BETA	2.08737373133259e-14	0.112210863632468	8.46546013262661e-14	2
RB1|RB	4.99498429432074e-11	0.111084042147619	1.58536458037137e-10	2
CDK1|CDK1	3.49770496658201e-09	0.109693793843723	8.51108208534956e-09	2
CCNE1|CYCLIN_E1	0.0138051387275664	0.108276534112121	0.0176802653879359	2
NRG1|HEREGULIN	1.47626449254616e-07	0.103419859600433	3.05001814969442e-07	2
CHEK1|CHK1_PS345	9.97722892139796e-07	0.0920480709735931	1.95090458373764e-06	2
CDKN1B|P27	6.9636724928788e-06	0.0900608998177489	1.25003629175447e-05	2
G6PD|G6PD	0.0367377413157293	0.0878321829848485	0.0446975852674706	2
AKT1 AKT2 AKT3|AKT_PT308	0.0180037008471746	0.0833729515536797	0.0227908120550939	2
AKT1 AKT2 AKT3|AKT	0.0356882294432963	0.082832045878355	0.0436632527825804	2
MYC|C-MYC	0.00112113636146678	0.071526175465368	0.0016368590877415	2
PIK3CA |PI3K-P110-ALPHA	0.0025581835081483	0.046901205482684	0.00356842158142979	2
AKT1S1|PRAS40_PT246	0.00709415476845292	0.0419497477008658	0.0093031131394682	2
RAF1|C-RAF_PS338	0.00698708479048191	0.038186739934632	0.0092179010187683	2
MET|C-MET_PY1235	0.0018781520631983	0.0376820997978355	0.0026708785833794	2
CDH2|N-CADHERIN	0.0356114511373499	-0.038885537951948	0.0436632527825804	2
CASP3|CASPASE-3	0.0109129122677449	-0.0437283420922078	0.0140583987449184	2
CASP8|CASPASE-8	0.0107632196811289	-0.0460953575069264	0.013947604202173	2
BIRC2 |CIAP	0.00576038054062646	-0.0472612294099567	0.00778718110121725	2
BAD|BAD_PS112	0.0251281116169896	-0.0478423738021645	0.0312673661597768	2
ESR1|ER-ALPHA_PS118	0.000233768123725845	-0.0631939203103896	0.000358008525146574	2
PCNA|PCNA	0.00353902946240578	-0.0632530648974026	0.00487451227840796	2
MAPK9|JNK2	0.00194310669095887	-0.0640009670835498	0.0027390199424776	2
ADAR|ADAR1	3.97781369249049e-05	-0.0686170646748918	6.71969668183634e-05	2
TP53BP1|53BP1	0.0293034416126254	-0.068878629287013	0.0362568006393501	2
CCNE2|CYCLIN_E2	0.000357788028938379	-0.0693008430194805	0.000540383298879345	2
YAP1|YAP	0.00153644423030852	-0.071784682764935	0.00219922409436318	2
EGFR|EGFR_PY1173	1.52800202905861e-09	-0.0840245515268398	3.98371957575995e-09	2
IRS1|IRS1	0.00149684658041688	-0.0849224836238095	0.00215664079678485	2
CHEK2|CHK2_PT68	4.72771587263222e-05	-0.0849715392896104	7.78473515869516e-05	2
CDKN1B|P27_PT157	1.42065885817609e-07	-0.0895643573952381	2.99157971096696e-07	2
SRC|SRC	0.00142596777339469	-0.0913343402012987	0.0020681254461817	2
PDK1|PDK1	3.74134481095865e-07	-0.0958262396177489	7.51701388623802e-07	2
YBX1|YB-1_PS102	1.06968249037311e-08	-0.0989770029683982	2.54630940643164e-08	2
EIF4G1|EIF4G	0.0164168511921456	-0.10243133945671	0.0209028512272086	2
RAB11A RAB11B|RAB11	6.52682778236469e-05	-0.103380200416017	0.000105101123848373	2
MS4A1|CD20	3.07338706162183e-07	-0.104840533965801	6.27298712453216e-07	2
TUBA1B|ACETYL-A-TUBULIN-LYS40	0.0210785460832425	-0.10780748831645	0.026529894208219	2
EGFR|EGFR	0.000888100586219009	-0.110788458892208	0.00133215087932851	2
ERRFI1|MIG-6	0.000100602717867952	-0.111791771782251	0.000158503562684039	2
JAK2|JAK2	4.44325318240774e-06	-0.114071836845455	8.17707938611172e-06	2
ANXA7|ANNEXIN_VII	0.000121768642232624	-0.114916289749351	0.000190480947492462	2
GAB2|GAB2	0.000134780191396065	-0.117262397412554	0.000209339446210909	2
EIF4EBP1|4E-BP1	3.27121772638319e-06	-0.120246142901732	6.17583346618895e-06	2
ACACA ACACB|ACC_PS79	0.0480292138665129	-0.131926286830736	0.0581126952307532	2
PXN|PAXILLIN	0.00657679260976571	-0.133806009841991	0.00878242427767494	2
MSH6|MSH6	4.23664212489466e-06	-0.139934394969264	7.86292055382992e-06	2
YAP1|YAP_PS127	0.00195108269875117	-0.145038022097403	0.0027390199424776	2
PDCD4|PDCD4	0.000320833990399726	-0.146914235746753	0.00048793502706625	2
STAT5A|STAT5-ALPHA	0.00274339578016258	-0.147914379898268	0.00380255491047851	2
CDKN2A|P16_INK4A	0.00403250088417587	-0.148135505248052	0.00551948558521572	2
MAPK14|P38_MAPK	6.41277991502495e-05	-0.157505807282684	0.000104029540843738	2
COL6A1|COLLAGEN_VI	6.62665029112254e-05	-0.158800028537229	0.000105929665237652	2
HSPA1A|HSP70	0.000942011639338978	-0.16264300084632	0.00140340509534174	2
TSC2|TUBERIN	0.00106496509175213	-0.169054971366667	0.00156528426237394	2
RBM15|RBM15	1.72259493358075e-05	-0.178976909158874	2.97045897995421e-05	2
PDK1|PDK1_PS241	6.5487154767608e-08	-0.181055472618615	1.42843589365494e-07	2
MAP2K1|MEK1	2.11429879489055e-06	-0.184163448898268	4.02636031374809e-06	2
CTNNB1|BETA-CATENIN	0.021750163961075	-0.184728304492208	0.0272187766141453	2
PRKCA |PKC-ALPHA	3.98886104401244e-05	-0.188953142288745	6.71969668183634e-05	2
LCK|LCK	3.69284488275656e-06	-0.193432520210822	6.91224811387766e-06	2
SMAD1|SMAD1	4.00325082265475e-14	-0.199922567241991	1.59402169120253e-13	2
NF2|NF2	9.73747799202006e-10	-0.203223012661039	2.60061912225902e-09	2
YWHAZ|14-3-3_ZETA	7.89105071741222e-06	-0.207844894529437	1.3864274113415e-05	2
TIGAR|TIGAR	4.0380838844705e-05	-0.215647702925974	6.72712845275358e-05	2
ERBB3|HER3_PY1289	6.53959700004019e-18	-0.222788252404762	4.09191926573943e-17	2
TFRC|TFRC	3.70370325339206e-05	-0.223700182785714	6.33680478510048e-05	2
EEF2|EEF2	9.71679630074267e-09	-0.228188727799567	2.33843779105785e-08	2
MTOR|MTOR	2.18158128472255e-10	-0.228494792338961	6.45630136965187e-10	2
ARAF|A-RAF	6.18506055562208e-08	-0.231213698435065	1.36821036533458e-07	2
EIF4EBP1|4E-BP1_PS65	1.94789892496138e-17	-0.233696002059307	1.06647466141636e-16	2
BCL2L11|BIM	7.85666373217715e-10	-0.234691863714719	2.12420908314419e-09	2
BRAF|B-RAF_PS445	4.14580714790792e-07	-0.235441746791775	8.25392513992577e-07	2
TGM2|TRANSGLUTAMINASE	8.71113838252557e-05	-0.23603191697013	0.00013824197867921	2
BAX|BAX	1.57685693599676e-10	-0.238929469772727	4.79627318032348e-10	2
STK11|LKB1	3.17645541593268e-13	-0.239611322899134	1.12200602595041e-12	2
RICTOR|RICTOR_PT1135	5.64427765037574e-20	-0.245605921769264	5.00623134080288e-19	2
BID|BID	1.82723852359902e-15	-0.248563027604762	8.33677576392053e-15	2
EIF4EBP1|4E-BP1_PT70	2.01969553744855e-13	-0.252967635065368	7.37188871168721e-13	2
DIABLO|SMAC	8.05377813433849e-08	-0.255502223860173	1.72919354060797e-07	2
IRF1|IRF-1	8.04784200716618e-18	-0.257057945870563	4.76345243126863e-17	2
GSK3A GSK3B|GSK3-ALPHA-BETA	6.16339028798257e-13	-0.258797953764935	2.14251186201299e-12	2
CCND1|CYCLIN_D1	2.63443698855965e-10	-0.268610737863636	7.39668846787902e-10	2
ATM|ATM	1.23948671582197e-06	-0.287128418138961	2.40219106871692e-06	2
PIK3R1 PIK3R2|PI3K-P85	7.74461540990338e-14	-0.296590986093939	2.87469622842176e-13	2
COG3|COG3	6.58776371046342e-08	-0.303541320468831	1.42843589365494e-07	2
RPTOR|RAPTOR	1.78819211714037e-18	-0.307397918022944	1.26327120533465e-17	2
ERCC5|ERCC5	1.42660962895414e-09	-0.307676989248052	3.76418685230068e-09	2
TSC1|TSC1	7.50919954595083e-12	-0.307904259893939	2.45449955307945e-11	2
CAV1|CAVEOLIN-1	4.0547075605638e-05	-0.313637409790043	6.72712845275358e-05	2
FASN|FASN	0.0102974644024793	-0.314177464349351	0.0134234803818034	2
SYK|SYK	7.91339846656109e-06	-0.315498365341558	1.3864274113415e-05	2
RPS6|S6	2.56875996338658e-10	-0.317344184375325	7.39668846787902e-10	2
ABL1|C-ABL	1.09269799267373e-25	-0.325567026134632	3.01342591528207e-24	2
EIF4EBP1|4E-BP1_PT37_T46	5.86760092089266e-10	-0.340991761131169	1.60625575209437e-09	2
BRAF|B-RAF	7.66769143952477e-11	-0.34122676597013	2.36510482430412e-10	2
BCL2A1|BCL2A1	4.56989296848402e-14	-0.347396315114719	1.78715457160357e-13	2
CHEK1|CHK1_PS296	8.35317151327479e-21	-0.354531120901732	9.14672280703589e-20	2
DPP4|CD26	7.78638436892118e-07	-0.357022896399567	1.53623259170607e-06	2
ARID1A|ARID1A	2.80863697751952e-13	-0.382606328245455	1.00834671815865e-12	2
SMAD3|SMAD3	1.10079485489756e-25	-0.39261335205671	3.01342591528207e-24	2
PEA15|PEA15	2.07623310889298e-17	-0.393639476254113	1.1090123191404e-16	2
GAPDH|GAPDH	1.11835471035862e-07	-0.394008294129437	2.37786098610231e-07	2
MAPK1|ERK2	2.39938827438078e-19	-0.399842702798701	1.94617048921997e-18	2
KDR|VEGFR2	5.22899089750958e-15	-0.400302144414286	2.24539020893058e-14	2
BCL2L1|BCL-XL	4.05306088061243e-19	-0.413907965595238	3.17007261733615e-18	2
RAF1|C-RAF	1.46861120162779e-21	-0.421836868497403	1.78681029531381e-20	2
PRKAA1|AMPK_ALPHA	6.39976515568121e-17	-0.433336378141558	3.18533765703224e-16	2
YBX1|YB-1	2.39902147497009e-15	-0.462314755335498	1.07221572044582e-14	2
XRCC5|KU80	9.19382345808153e-18	-0.471705191967532	5.29854562452594e-17	2
FN1|FIBRONECTIN	3.09352789702956e-07	-0.525159176867965	6.27298712453216e-07	2
SERPINE1|PAI-1	1.94253183697096e-08	-0.553318911861039	4.57434916448e-08	2
ACACA|ACC1	1.43774079891496e-07	-0.573873147901732	2.9987165234512e-07	2
PEA15|PEA15_PS116	3.16608438194407e-12	-0.630499209016883	1.06672689176269e-11	2
BRD4|BRD4	7.63669734656351e-17	-0.638217045047186	3.64997859811397e-16	2
SQSTM1|P62-LCK-LIGAND	4.99173242530135e-05	1.06618870702642	0.000227747791904374	3
SERPINE1|PAI-1	2.5035090334418e-06	0.954956716782822	2.68199613208622e-05	3
FASN|FASN	3.01544100851174e-07	0.83602350209633	6.1634712601403e-06	3
ACACA|ACC1	1.08934363431987e-05	0.675368933450016	6.27805936621188e-05	3
FN1|FIBRONECTIN	1.93745516967231e-06	0.648573611168459	2.49589813034256e-05	3
GAPDH|GAPDH	0.000127914581649953	0.515040418163398	0.00048298781691965	3
TFRC|TFRC	0.000105000891961131	0.409830391390225	0.000410628488205137	3
PEA15|PEA15_PS116	0.00162350979964574	0.409697699862543	0.00423272197764782	3
RAF1|C-RAF	3.09580748226225e-07	0.341775870737583	6.1634712601403e-06	3
RPS6|S6	2.58154601888186e-07	0.335492224948592	6.1634712601403e-06	3
YBX1|YB-1	6.71216618101545e-06	0.332998737417748	4.65178296332105e-05	3
DPP4|CD26	4.96543351633666e-05	0.298677363325688	0.000227747791904374	3
BRAF|B-RAF	8.24820652481579e-05	0.295606711454128	0.000334510597950863	3
EEF2|EEF2	0.000488290425213305	0.277767001160234	0.00152765147316734	3
BCL2A1|BCL2A1	1.54487763393745e-05	0.270271295127017	8.67508209826414e-05	3
ACACA ACACB|ACC_PS79	0.0243878326887571	0.265707109871718	0.0441399616432876	3
MAPK1|ERK2	0.000281489808447006	0.25825610328298	0.000948404123844528	3
ABL1|C-ABL	1.13845875762615e-08	0.254965821757197	1.24661233960063e-06	3
EIF4G1|EIF4G	5.94812119522906e-05	0.253581129484815	0.000250507411875993	3
TGM2|TRANSGLUTAMINASE	0.0115189476731145	0.252065365874565	0.0227265724361448	3
CHEK1|CHK1_PS296	5.81247358453487e-07	0.251136334449383	1.06077642917761e-05	3
COG3|COG3	0.00116065079352962	0.250200770744227	0.00321750030105047	3
PEA15|PEA15	3.56973287814816e-05	0.242060394121006	0.000173727000069877	3
SMAD3|SMAD3	6.2030143639482e-08	0.241424343097279	2.26410024284109e-06	3
TUBA1B|ACETYL-A-TUBULIN-LYS40	0.00141943280936744	0.234543057350997	0.00388569731564337	3
RPTOR|RAPTOR	1.01335410262872e-05	0.22966441402515	6.08052234384197e-05	3
KDR|VEGFR2	0.000851829371503234	0.2270586007882	0.00252095449134065	3
BCL2L11|BIM	0.000177782003542702	0.225333673994147	0.000638266537309045	3
PRDX1|PRDX1	0.00463411140191506	0.218693501876779	0.0102152968028125	3
TIGAR|TIGAR	0.0165563532281263	0.218501798541126	0.0315290552779101	3
GSK3A GSK3B|GSK3-ALPHA-BETA	0.000331203543970491	0.213089299319677	0.00109899357772027	3
DIABLO|SMAC	0.00524172735896947	0.212163722208004	0.011282954040296	3
EIF4EBP1|4E-BP1_PT70	0.000676028709941735	0.206506876372509	0.00205625399273944	3
XRCC5|KU80	0.0250085100719724	0.191412058338342	0.0448923254570652	3
MTOR|MTOR	0.00111906792463388	0.190113657243436	0.00314199840377974	3
CDH3|P-CADHERIN	0.0039672475886587	0.188917366100127	0.00895698166923974	3
ARID1A|ARID1A	0.016361198173916	0.188536376424707	0.031430722807786	3
PRKAA1|AMPK_ALPHA	0.00108265759812166	0.186885865226352	0.00311976334195584	3
STK11|LKB1	5.27545982032445e-06	0.184642694407941	4.27898407648539e-05	3
BCL2L1|BCL-XL	0.00466451908804223	0.184032780550933	0.0102152968028125	3
ERBB3|HER3_PY1289	2.59970575820776e-05	0.182452368940367	0.00013555608596369	3
CCND1|CYCLIN_D1	0.00461591690219743	0.177978461728409	0.0102152968028125	3
ERRFI1|MIG-6	0.00188532999849569	0.177739406220025	0.00474583068586846	3
YWHAZ|14-3-3_ZETA	0.0354443562778701	0.175052062143151	0.0616056668639171	3
BID|BID	8.49498924126084e-06	0.168774444805599	5.31543612524607e-05	3
RICTOR|RICTOR_PT1135	4.24208909000482e-05	0.165987461211167	0.000201960328415447	3
EGFR|EGFR	0.00252463043011705	0.155806232573711	0.00600971808908298	3
TSC1|TSC1	0.0091777778491263	0.150588171168143	0.0189616353675345	3
IRF1|IRF-1	0.000239341063334005	0.150267405984024	0.000818995201096048	3
SMAD1|SMAD1	1.97421600122508e-08	0.141918297925815	1.38680435597798e-06	3
PIK3R1 PIK3R2|PI3K-P85	0.00317319100416104	0.13754571452689	0.00739285989267306	3
LCK|LCK	0.025756398915819	0.135734493804018	0.0458589541671899	3
EIF4EBP1|4E-BP1_PS65	0.000564567589623341	0.134666238337077	0.00174141270602129	3
ESR1|ER-ALPHA_PS118	2.57177711295939e-06	0.131480067395603	2.68199613208622e-05	3
MS4A1|CD20	5.30405834688624e-05	0.127335202682537	0.000228779693869316	3
ANXA7|ANNEXIN_VII	0.0223420972027008	0.124512909779658	0.0418195805244624	3
YBX1|YB-1_PS102	0.00045176077116819	0.119846532356691	0.00143384940414252	3
PARK7|DJ-1	0.0243644595604489	0.114677630424707	0.0441399616432876	3
EGFR|EGFR_PY1173	3.87040965062351e-06	0.109848117203575	3.54980643151289e-05	3
PCNA|PCNA	0.00358943752523447	0.0981403011545397	0.00818840435444113	3
ADAR|ADAR1	0.0011183563493555	0.0973931431668776	0.00314199840377974	3
CCNE2|CYCLIN_E2	0.00205305275924708	0.0971016843899083	0.00499576171416789	3
BIRC2 |CIAP	0.0216872078819149	0.080752396078298	0.0409439528115462	3
EIF4E|EIF4E	0.0274952063046117	0.0726653762042075	0.0485600821024997	3
CDKN1B|P27_PT157	0.00213261898709978	0.0692435670194559	0.00513234679313024	3
CHEK2|CHK2_PT68	0.0225329246661487	0.0681207148049668	0.0418195805244624	3
STMN1|STATHMIN	0.047817054785372	0.0678466137546663	0.0818119921718474	3
PDK1|PDK1	0.0110721319066953	0.0596422941573869	0.0220436080687843	3
MAPK8|JNK_PT183_PY185	0.0461704278376552	-0.0520993202503955	0.0796167220192637	3
RB1|RB	0.00961445339122695	-0.0601378034436887	0.0194959749322102	3
ACVRL1|ACVRL1	0.0322914085944395	-0.0744317967597279	0.056574547857458	3
BRCA2|BRCA2	0.0109900450243134	-0.0797073913218918	0.0220436080687843	3
BAK1|BAK	0.00525507448452142	-0.0812357177755457	0.011282954040296	3
CDK1|CDK1	0.00329292694483704	-0.0819574252674786	0.0075910631675717	3
PGR|PR	0.00205046040776233	-0.0883930339236001	0.00499576171416789	3
CTNNA1|ALPHA-CATENIN	0.000359925630976118	-0.0992278950890541	0.0011591722527025	3
CDKN1B|P27	0.00621288463237177	-0.10144907681509	0.0132099197523244	3
NOTCH1|NOTCH1	0.000190589515059997	-0.103216276842297	0.000662525457113323	3
YWHAB|14-3-3_BETA	5.31470520066126e-05	-0.10798861201914	0.000228779693869316	3
SMAD4|SMAD4	0.000348731078865129	-0.12099156606944	0.00113988218315617	3
CDK1|CDK1_PY15	0.00147245531282093	-0.122678835719234	0.00398108288281214	3
FOXO3|FOXO3A_PS318_S321	6.40772517576399e-07	-0.125757015072604	1.07945524114793e-05	3
PRKCD|PKC-DELTA_PS664	5.3277462955868e-05	-0.129159287248181	0.000228779693869316	3
XRCC1|XRCC1	0.00153288785532295	-0.130319972185543	0.00409393219897227	3
SRSF1|SF2	0.00103008605286429	-0.154934707953654	0.00300785127436373	3
AR|AR	0.00951090050651481	-0.164230620674312	0.0194662356161378	3
CHEK1|CHK1	0.00161702456815939	-0.165930529901772	0.00423272197764782	3
RPS6KA1|P90RSK_PT359_S363	8.64342132253693e-05	-0.167148091800221	0.000344165321751925	3
FOXM1|FOXM1	0.0001531501549106	-0.168325998372509	0.000568472608905447	3
MTOR|MTOR_PS2448	0.00193844702913233	-0.16847032917099	0.00482408976568159	3
JUN|C-JUN_PS73	7.93833617087052e-06	-0.172692942215913	5.11322241594307e-05	3
MET|C-MET	0.00871055173432093	-0.178212948836919	0.0181677221887265	3
ERBB2|HER2_PY1248	5.63064103453869e-06	-0.180513484314299	4.4039656662999e-05	3
STAT3|STAT3_PY705	0.000190533768107695	-0.183104020878994	0.000662525457113323	3
BECN1|BECLIN	0.000120287527186371	-0.184119512256406	0.000462157341295004	3
ARAF|A-RAF_PS299	2.53297599265384e-08	-0.184574383406675	1.38680435597798e-06	3
PARP1|PARP_CLEAVED	2.48309952471308e-05	-0.184934498379469	0.000132633852661504	3
XBP1|XBP1	0.00185764874024262	-0.197750752870136	0.00473052411759458	3
PECAM1|CD31	2.43126740747638e-05	-0.205932614273489	0.000132633852661504	3
TSC2|TUBERIN_PT1462	0.000801871168205976	-0.211813090922335	0.00240561350461793	3
GSK3A GSK3B|GSK3_PS9	0.012613688069354	-0.215609899103923	0.0244459972317569	3
NKX2-1|TTF1	2.27915875715711e-06	-0.216190681107086	2.68199613208622e-05	3
MAPK14|P38_PT180_Y182	0.0237039195690119	-0.217715411139987	0.0436231797110387	3
SNAI1|SNAIL	1.17804777642495e-06	-0.21952988220832	1.61245289398165e-05	3
ERBB2|HER2	0.00731529265604055	-0.237528087593641	0.0154043181891623	3
BCL2|BCL-2	3.335737030786e-06	-0.250098458565169	3.32057458973697e-05	3
RPS6KB1|P70S6K_PT389	5.24926369224008e-06	-0.252180588077665	4.27898407648539e-05	3
PTPN11|SHP-2_PY542	7.47333270561013e-07	-0.256585465400032	1.16904275894901e-05	3
EGFR|EGFR_PY1068	3.21726435853472e-05	-0.27371691435068	0.000160132021481614	3
GUSP4|DUSP4	1.37142912728841e-07	-0.276966759406675	3.75428723595202e-06	3
AKT1 AKT2 AKT3|AKT	0.000166124332858072	-0.280003165719867	0.000606353814931963	3
RAD51|RAD51	6.13687977952378e-06	-0.292964785985289	4.57841211295154e-05	3
PREX1|PREX1	7.28484469056274e-06	-0.302152255644891	4.83448784010073e-05	3
INPP4B|INPP4B	1.00496926854045e-07	-0.30463321816403	3.14411814014798e-06	3
TP53|P53	3.89019882905522e-06	-0.31105849735068	3.54980643151289e-05	3
MSH2|MSH2	6.79712579115404e-06	-0.312748834671781	4.65178296332105e-05	3
COPS5|JAB1	1.02730286174499e-05	-0.327075569214964	6.08052234384197e-05	3
FOXO3|FOXO3A	2.35544572908763e-06	-0.339863652250395	2.68199613208622e-05	3
DIRAS3|DIRAS3	6.27179741500211e-06	-0.34031626897485	4.57841211295154e-05	3
AKT1 AKT2 AKT3|AKT_PS473	0.0025910007865094	-0.343631450226669	0.00610138894887697	3
PTEN|PTEN	7.02708081537501e-05	-0.344106810785985	0.000290364282748515	3
SRC|SRC_PY416	5.25998122826667e-06	-0.355751406808763	4.27898407648539e-05	3
MYH11|MYH11	0.0123854191002522	-0.36348601169361	0.0242179177049574	3
ANXA1|ANNEXIN-1	1.11195738232057e-06	-0.380143349033375	1.61245289398165e-05	3
ESR1|ER-ALPHA	3.52866505988454e-08	-0.394975745317779	1.54555529622943e-06	3
MAPK1 MAPK3|MAPK_PT202_Y204	4.07988692562694e-10	-0.448160476751819	8.934952367123e-08	3
SRC|SRC_PY527	2.76426706080409e-05	-0.473104135000791	0.000140784764259557	3
PRKAA1|AMPK_PT172	0.0018041636388945	-0.512126819002373	0.00464837455197524	3
BRD4|BRD4	1.21783732363893e-05	0.407977325629032	0.000666765934692314	4
PRKAA1|AMPK_PT172	0.0165102970370814	0.355559633582949	0.0728700987742338	4
ACACA ACACB|ACC_PS79	0.0113591868242449	0.296851645611751	0.0557765544231393	4
EPPK1|EPPK1	0.0460796070151372	0.268026759309908	0.142132872342465	4
PRKCA |PKC-ALPHA_PS657	0.000505997471717195	0.243149660819124	0.00693086821700498	4
PRKCA |PKC-ALPHA	0.00898775399520711	0.202235140504608	0.0492918224259541	4
MSH6|MSH6	0.0172665867983438	0.186786487852535	0.074144755075241	4
ERBB2|HER2	0.0292662121940168	0.186455978025346	0.106821674508161	4
RB1|RB_PS807_S811	0.0222327911066956	0.182947922945853	0.086946093792256	4
XRCC5|KU80	0.0163603725378671	0.174585661345622	0.0728700987742338	4
MSH2|MSH2	0.000148043735889683	0.171010104656682	0.00324215781598406	4
RBM15|RBM15	0.00655828562525048	0.168271804259217	0.0422430750567604	4
CDH1|E-CADHERIN	0.0391828267853204	0.164622651035714	0.126358990524706	4
TP53|P53	0.00164828322297934	0.157930291528802	0.0164079102651125	4
RPS6KB1|P70S6K	0.000686805456890618	0.157498367513825	0.0088476702975909	4
ERBB3|HER3	0.0357567071759	0.155936071144009	0.124297124944795	4
EEF2K|EEF2K	0.00815035588793243	0.153578148846774	0.0469717878804527	4
BAP1|BAP1-C-4	5.64779808244779e-05	0.153312222123272	0.00161663712253185	4
EGFR|EGFR_PY1068	0.0351539246917268	0.147090950957373	0.124172733991745	4
PRKCB|PKC-PAN_BETAII_PS660	0.0292067012203695	0.144348992616359	0.106821674508161	4
COPS5|JAB1	0.00774255449101708	0.141909339415899	0.0458275522576416	4
DIRAS3|DIRAS3	0.0166370088525648	0.136523665180875	0.0728700987742338	4
FOXO3|FOXO3A	0.0105886099221118	0.131100600447005	0.0557765544231393	4
CHEK1|CHK1	0.000506364801242373	0.127596495336405	0.00693086821700498	4
SRC|SRC_PY416	0.0202081529893409	0.11152907206682	0.080465190993921	4
SHC1|SHC_PY317	0.00900307258921537	0.099576998046083	0.0492918224259541	4
PRKCD|PKC-DELTA_PS664	0.000220079954382788	0.0940688116912442	0.00438159181907551	4
TSC2|TUBERIN_PT1462	0.0434196594361542	0.0924122206417051	0.137810223427794	4
EIF4G1|EIF4G	0.0443653013161623	0.092264069718894	0.138800014117708	4
MTOR|MTOR_PS2448	0.0471123684976448	0.0872477257269585	0.143300120847003	4
FOXM1|FOXM1	0.000806706689900954	0.0860880022534562	0.00981493139379494	4
SRSF1|SF2	0.0314168716680897	0.0722573958732719	0.112791719595273	4
CHEK1|CHK1_PS345	0.0135211712307187	0.0696820113824885	0.0630029042452637	4
XRCC1|XRCC1	0.0113366710334475	0.0684223895541475	0.0557765544231393	4
CCNE2|CYCLIN_E2	0.0385840625933819	0.0428018380184332	0.126358990524706	4
RAF1|C-RAF_PS338	0.00561638460970335	-0.043930807625576	0.0384371321726573	4
CHEK2|CHK2_PT68	0.0391190416977527	-0.0547441367315668	0.126358990524706	4
YBX1|YB-1_PS102	0.0481110319256182	-0.0574363931624424	0.144333095776855	4
BIRC2 |CIAP	0.0023801842910782	-0.06380422625	0.0208973261256541	4
CASP8|CASPASE-8	0.00155804879187044	-0.0658036528145161	0.0162482231152203	4
MRE11A|MRE11	5.90552373527618e-05	-0.0660165241831797	0.00161663712253185	4
DVL3|DVL3	0.0108571642419461	-0.0730371880702765	0.0557765544231393	4
MYC|C-MYC	0.00038322159059301	-0.0758436285069125	0.00645580987229763	4
WWTR1|TAZ	0.00326951853434422	-0.0771709186163594	0.0273385835952596	4
YAP1|YAP	0.00495383473292935	-0.0788822944193548	0.0349964453713396	4
IGFR1|IGF1R_PY1135_Y1136	0.00130053254776644	-0.083403583609447	0.0142408313980425	4
MYH9|MYOSIN-IIA_PS1943	0.0124264521210164	-0.0839452082327189	0.0591607177065781	4
STK11|LKB1	0.0045100888860252	-0.0854849696359447	0.032923648867984	4
GSK3A GSK3B|GSK3-ALPHA-BETA	0.0392347550487671	-0.0876646424861751	0.126358990524706	4
MAP2K1|MEK1_PS217_S221	7.53027343845952e-06	-0.0879845571912442	0.000549709961007545	4
ERRFI1|MIG-6	0.00736760453949439	-0.0890971354274194	0.0448195942819242	4
RICTOR|RICTOR_PT1135	0.0176974823512059	-0.0908722364389401	0.0745336275945018	4
ABL1|C-ABL	0.0193892554043474	-0.0915054227396313	0.0786342024731867	4
STMN1|STATHMIN	0.00034271038924302	-0.10191945918318	0.00625446460368512	4
EIF4EBP1|4E-BP1_PT70	0.00636448527730325	-0.101932213723502	0.042237038658467	4
ANXA7|ANNEXIN_VII	0.0193712917526034	-0.102420623640553	0.0786342024731867	4
CHEK1|CHK1_PS296	0.00219621662878587	-0.108331746105991	0.0208973261256541	4
BID|BID	0.00337051030626488	-0.110382168367512	0.0273385835952596	4
SRC|SRC	0.0247603108152006	-0.127164742932028	0.0951317205005076	4
HSPA1A|HSP70	0.0271898133058169	-0.145792242556452	0.102664984723688	4
CLDN7|CLAUDIN-7	4.18000282586281e-05	-0.16773750066129	0.00161663712253185	4
BCL2A1|BCL2A1	0.00102679765739397	-0.170997503715438	0.0118351940510147	4
BCL2L1|BCL-XL	0.00732653091776254	-0.177855484869816	0.0448195942819242	4
COL6A1|COLLAGEN_VI	0.000122369604089256	-0.195725311504608	0.0029776603661719	4
SETD2|SETD2	0.000445224221519318	-0.212410757646313	0.00693086821700498	4
YWHAZ|14-3-3_ZETA	4.86536278106479e-05	-0.21485899515553	0.00161663712253185	4
TIGAR|TIGAR	0.00238553951206097	-0.2214151769447	0.0208973261256541	4
CDKN2A|P16_INK4A	0.0114609358403711	-0.223123850403226	0.0557765544231393	4
SYK|SYK	0.0373120991610639	-0.227127289656682	0.126358990524706	4
SQSTM1|P62-LCK-LIGAND	0.0036301089692657	-0.368646873102535	0.0283926380096139	4
RAB25|RAB25	4.39257051060895e-07	-0.4663219415553	4.8098647091168e-05	4
SERPINE1|PAI-1	0.00411179626278302	-0.482284005646313	0.0310511510879132	4
MYH11|MYH11	4.52752098553528e-08	-0.695529706200461	9.91527095832226e-06	4
RAB25|RAB25	0.00420686133457585	0.424023667931509	0.00837547847520101	5
SETD2|SETD2	0.000256901209649647	0.347709089711642	0.00067784777003943	5
RPS6|S6_PS240_S244	0.000643341333185258	0.346240166767004	0.00154826101063265	5
FASN|FASN	0.0385493373305147	0.31565595733423	0.0565703213180604	5
TP53|P53	1.12645167157108e-11	0.314706808568016	2.46692916074067e-09	5
DIRAS3|DIRAS3	8.86747050546746e-11	0.309828619916957	4.85494010174343e-09	5
COPS5|JAB1	4.25989550103665e-10	0.306531730946694	1.33273873532432e-08	5
FOXO3|FOXO3A	5.25853788750144e-11	0.297878060941316	3.83873265787605e-09	5
AKT1 AKT2 AKT3|AKT_PS473	1.3633764191892e-07	0.289933086219076	1.29817146001059e-06	5
MSH2|MSH2	2.54309550713556e-11	0.288283025888485	2.78468958031344e-09	5
ESR1|ER-ALPHA	2.05530486024494e-07	0.281740307341189	1.66708060886534e-06	5
SRC|SRC_PY416	7.50173801033134e-10	0.272485652428504	1.82542291584729e-08	5
AR|AR	3.00940192178131e-06	0.243066637534166	1.64764755217527e-05	5
MET|C-MET	5.98517987836253e-09	0.22128369543926	1.008272610278e-07	5
EGFR|EGFR_PY1068	4.76978599704499e-07	0.215279776831541	3.36962301081565e-06	5
ANXA1|ANNEXIN-1	1.76247744096999e-07	0.210855570827112	1.60826066488512e-06	5
EPPK1|EPPK1	0.00967262437956917	0.2103168595851	0.0175066507365756	5
ERBB2|HER2	0.00196675926754056	0.204896670235843	0.00434728819731083	5
INPP4B|INPP4B	4.80630672957541e-09	0.202682763813508	8.77150978147512e-08	5
SNAI1|SNAIL	6.57324543510166e-10	0.194262558173521	1.79942593785908e-08	5
MAPK1 MAPK3|MAPK_PT202_Y204	4.01077430357122e-05	0.19365355776479	0.000139422154362238	5
PTPN11|SHP-2_PY542	1.1857511904159e-08	0.192716022555995	1.73119673800721e-07	5
RB1|RB_PS807_S811	8.04907958592119e-05	0.182851068711009	0.000241472387577636	5
SRSF1|SF2	7.93145988462538e-09	0.180662801901772	1.24070693909497e-07	5
PARP1|PARP_CLEAVED	2.58511907547576e-10	0.179057544445903	9.43568462548652e-09	5
RPS6KB1|P70S6K_PT389	8.59982054491277e-08	0.170663702675577	9.41680349667948e-07	5
TSC2|TUBERIN_PT1462	1.86266206062436e-07	0.169575445036855	1.63169196510694e-06	5
XBP1|XBP1	7.9731876678488e-05	0.16886612067969	0.000241472387577636	5
CHEK1|CHK1	2.23698947912571e-07	0.16875922167273	1.68931274458114e-06	5
BCL2|BCL-2	1.27207493255432e-07	0.165460999302278	1.26629277376998e-06	5
PECAM1|CD31	5.7751302988768e-08	0.165012849264315	7.02640853030011e-07	5
GSK3A GSK3B|GSK3_PS9	7.57864093433078e-05	0.164912346330117	0.000237103194945492	5
SRC|SRC_PY527	0.00698158362908654	0.163971607741063	0.012957345887881	5
ACACA ACACB|ACC_PS79	0.0320375417097724	0.163217423348149	0.0487237613502789	5
RPS6|S6_PS235_S236	0.0079722299208331	0.159976399005853	0.0146715827954828	5
GUSP4|DUSP4	5.15753007517376e-06	0.154578746375989	2.56704337832512e-05	5
NKX2-1|TTF1	6.55889424743531e-08	0.151013722313034	7.55998863257017e-07	5
SCD|SCD	1.28170665314381e-05	0.148193976980544	5.29610862336782e-05	5
PREX1|PREX1	8.65046550454791e-06	0.144528416378203	3.78890389099198e-05	5
BAP1|BAP1-C-4	4.50697589055536e-05	0.13863588396789	0.000149549654550246	5
FOXM1|FOXM1	6.45495434717606e-07	0.135105947423442	4.41760938134862e-06	5
ARAF|A-RAF_PS299	2.0151175473336e-07	0.134881275049193	1.66708060886534e-06	5
RAD51|RAD51	0.00134710416972196	0.126428862747074	0.00307308138717822	5
PTEN|PTEN	0.00585913635651439	0.12603790121876	0.0113553173635102	5
BECN1|BECLIN	0.00011098808276701	0.115970770175419	0.0003198209227102	5
MTOR|MTOR_PS2448	1.09797344375427e-05	0.109795461286776	4.71482714082716e-05	5
RPS6KA1|P90RSK_PT359_S363	5.41376791624418e-05	0.098786008092534	0.000174355172596688	5
JUN|C-JUN_PS73	0.000141713103293083	0.0986241698223663	0.000397886790015195	5
PGR|PR	3.32240503814511e-06	0.0973240366790573	1.77465049598483e-05	5
CTNNA1|ALPHA-CATENIN	2.21556477994785e-07	0.0939115272111673	1.68931274458114e-06	5
AKT1 AKT2 AKT3|AKT_PT308	0.0388100326197581	0.0907236992950016	0.0565703213180604	5
EEF2K|EEF2K	0.0174549648106414	0.0871223376562796	0.0294049022579267	5
ERBB2|HER2_PY1248	0.0146867152366744	0.0868394414702626	0.0251280518502476	5
FOXO3|FOXO3A_PS318_S321	5.33730018849316e-06	0.0845500848359696	2.59748609173334e-05	5
NRAS|N-RAS	1.55285517174008e-05	0.0840258623544764	5.96623302826452e-05	5
ERCC1|ERCC1	7.80638300959686e-05	0.0813124295389117	0.000240788433676297	5
RICTOR|RICTOR	0.0364547571906216	0.0811009158571654	0.0546821357859324	5
CDKN1B|P27	2.95859106899889e-05	0.0810250429454287	0.000104505071630767	5
SMAD4|SMAD4	0.000231974985368535	0.0765530033886428	0.000619542948728161	5
PRKCD|PKC-DELTA_PS664	4.24024669045412e-05	0.0754826200270484	0.00014286369618607	5
ACVRL1|ACVRL1	0.00263836584938895	0.0687664600820943	0.00545096340581302	5
YWHAE|14-3-3_EPSILON	0.00101194096634832	0.0628455881051882	0.0023829577594654	5
BRCA2|BRCA2	0.00224910237432123	0.0625884538767795	0.00478207203860533	5
ITGA2|CD49B	0.0235921264865224	0.0620205898160392	0.0374396789894812	5
CHEK1|CHK1_PS345	0.00161893084814562	0.0593968519966782	0.00365511191488547	5
BAK1|BAK	0.000503225510492451	0.0593701745771908	0.00123827400896457	5
STAT3|STAT3_PY705	0.0473006584586424	0.0571141787378994	0.068150290805544	5
CDK1|CDK1_PY15	0.0119323590201478	0.0553996968214172	0.0207395763921617	5
RB1|RB	0.00233895404189518	0.0539623451747865	0.0049252974536062	5
CDK1|CDK1	0.0116954305875604	0.0489584755072762	0.0204903943894058	5
YWHAB|14-3-3_BETA	0.00673702220580654	0.0426689915218285	0.0126103236159969	5
PIK3CA |PI3K-P110-ALPHA	0.0127907118808064	0.0422316126085099	0.0220564244243827	5
MAPK8|JNK_PT183_PY185	0.0489299698977048	0.0350576648856374	0.0700370157359304	5
NOTCH1|NOTCH1	0.0373503792376763	0.0336643665866814	0.0554585121855583	5
CDKN1B|P27_PT198	0.0173774321682642	-0.0348076452516609	0.0294049022579267	5
IGFR1|IGF1R_PY1135_Y1136	0.0203017837185979	-0.0369020125775071	0.0329340046990588	5
CASP8|CASPASE-8	0.0306062484443267	-0.0383327385661183	0.0472025944317433	5
CDKN1B|P27_PT157	0.0019850631037949	-0.0498933104012971	0.00434728819731083	5
CDH2|N-CADHERIN	0.0197860947990046	-0.0499423482706422	0.0323369758282239	5
BAD|BAD_PS112	0.0390051073928179	-0.0501873749188548	0.0565703213180604	5
ESR1|ER-ALPHA_PS118	0.00951842041988997	-0.0522573606388801	0.0173711172662992	5
BIRC2 |CIAP	0.000101087728019689	-0.0662015271399874	0.000295176165817492	5
MAP2K1|MEK1_PS217_S221	0.000154742898430508	-0.0663091112216071	0.000423608684453516	5
ERRFI1|MIG-6	0.0191804692261384	-0.0673148460131288	0.0316150065832444	5
CHEK2|CHK2_PT68	0.00217277378646201	-0.0674607589043024	0.00466507312975667	5
EGFR|EGFR_PY1173	2.18946776764105e-05	-0.0679743701981968	8.12700747649813e-05	5
PCNA|PCNA	0.0113625023877568	-0.0709275507673205	0.0200676453461189	5
TP53BP1|53BP1	0.0284735369951724	-0.0710398571323948	0.0442248553329273	5
EIF4E|EIF4E	0.00212887067256217	-0.0716201842965834	0.00461606611179322	5
RPTOR|RAPTOR	0.0268994897643808	-0.0731118701086682	0.0420784875599957	5
STMN1|STATHMIN	4.09719101464316e-05	-0.0799973681203733	0.000140200755032321	5
YBX1|YB-1_PS102	7.39370926538852e-06	-0.0808427859473268	3.37337985233351e-05	5
EGFR|EGFR	0.0227711729586441	-0.0845154325540968	0.0364006341455698	5
EIF4EBP1|4E-BP1	0.0053489812755342	-0.0884344334351471	0.0104591687441249	5
CCNB1|CYCLIN_B1	0.0319679747558284	-0.0902321639602974	0.0487237613502789	5
PDK1|PDK1	1.91952670117606e-05	-0.0909970589818096	7.24786806133719e-05	5
SMAD1|SMAD1	4.60292089801305e-05	-0.0966964576879153	0.000150453683084307	5
ERBB3|HER3_PY1289	0.00046664191802688	-0.0967144478780449	0.00118830907032426	5
GAB2|GAB2	0.00667573677384888	-0.0983107307859854	0.0126033306333871	5
NF2|NF2	0.00343144162994474	-0.0988763101842771	0.00689436437576053	5
MAP2K1|MEK1	0.0187402170564817	-0.0993246568954445	0.0313290651554923	5
YAP1|YAP	3.59743233981932e-06	-0.10094286426906	1.87580400576293e-05	5
PDK1|PDK1_PS241	0.00119364345693437	-0.102801794268744	0.00275166228493292	5
DIABLO|SMAC	0.0374788118879572	-0.103359474932458	0.0554585121855583	5
CASP7|CASPASE-7_CLEAVEDD198	0.000553031593444864	-0.107128415527523	0.00134571021071584	5
YAP1|YAP_PS127	0.0191999811669932	-0.107233003804967	0.0316150065832444	5
KDR|VEGFR2	0.0102303118180611	-0.11126359233075	0.0182149454321576	5
PIK3R1 PIK3R2|PI3K-P85	0.00428479617250125	-0.113761054847042	0.00845378704304301	5
ARAF|A-RAF	0.0333114366206471	-0.114830652430718	0.0503117559994601	5
ANXA7|ANNEXIN_VII	8.81170050645063e-05	-0.116023952006802	0.00026077870417739	5
CCND1|CYCLIN_D1	0.0027731867736553	-0.120489252371243	0.00567596171430384	5
RAB11A RAB11B|RAB11	2.89534414912107e-05	-0.121759929298165	0.000103947601419265	5
RICTOR|RICTOR_PT1135	1.65286867459215e-06	-0.12468711173695	1.04567076775548e-05	5
EIF4EBP1|4E-BP1_PS65	1.18080511865598e-05	-0.124961199213382	4.97300617280115e-05	5
SRC|SRC	7.41573177776928e-05	-0.125575495198197	0.000235368878163982	5
COG3|COG3	0.0261600289901595	-0.126937707791996	0.0412161607830571	5
BRAF|B-RAF	0.0216268796858919	-0.130010152841031	0.0348256371412524	5
IRF1|IRF-1	1.58127151500919e-06	-0.131838836111832	1.04567076775548e-05	5
STK11|LKB1	2.30672504473758e-06	-0.136736194171939	1.32940206525666e-05	5
EIF4EBP1|4E-BP1_PT70	0.000474925354880166	-0.139320763784087	0.00119272816938872	5
CLDN7|CLAUDIN-7	0.000271178755186547	-0.140868138019139	0.000707001754593498	5
BID|BID	8.28415650075407e-06	-0.142679007388327	3.70251076258192e-05	5
CDKN2A|P16_INK4A	0.00613890237431615	-0.14525158137757	0.0117730772175218	5
ARID1A|ARID1A	0.0098845787116023	-0.148536007928662	0.0177436289986959	5
MAPK14|P38_MAPK	2.71503940454701e-05	-0.152111921599652	9.90989382659659e-05	5
SMAD3|SMAD3	6.4793224018081e-06	-0.15225752929342	3.08472088259994e-05	5
RPS6|S6	0.00238209697824214	-0.1543011317205	0.00496837369747646	5
PDCD4|PDCD4	0.00187038554059492	-0.155808875853369	0.00417973911622742	5
BCL2L11|BIM	0.000141521702882461	-0.157732966413002	0.000397886790015195	5
BRAF|B-RAF_PS445	0.00115648013323183	-0.164822771559475	0.00269435265082735	5
BCL2L1|BCL-XL	0.00325350201334622	-0.166284777181746	0.00659737908261872	5
RAF1|C-RAF	0.000479269766695012	-0.168053510915375	0.00119272816938872	5
ABL1|C-ABL	5.32493516889755e-08	-0.168267913945745	6.85976942346214e-07	5
HSPA1A|HSP70	0.000198618206647014	-0.169737266780291	0.000537004780934519	5
EEF2|EEF2	2.87659465542721e-06	-0.176022408370611	1.61531853727836e-05	5
CHEK1|CHK1_PS296	3.51876582130023e-07	-0.18432147089671	2.56869904954917e-06	5
GSK3A GSK3B|GSK3-ALPHA-BETA	1.03853193159577e-07	-0.193303970657861	1.08304044294987e-06	5
COL6A1|COLLAGEN_VI	1.6711633274631e-06	-0.194065062103606	1.04567076775548e-05	5
XRCC5|KU80	0.000151541997554189	-0.194963890697722	0.000420097436257815	5
PEA15|PEA15	1.53645402463363e-05	-0.199425869845777	5.96623302826452e-05	5
LCK|LCK	4.35750202106532e-06	-0.225380203836286	2.2192859130542e-05	5
TIGAR|TIGAR	6.8981241493825e-06	-0.2308398906354	3.2142323164144e-05	5
BAX|BAX	3.29912930570165e-09	-0.245693280419646	6.56826652680601e-08	5
BCL2A1|BCL2A1	1.63339018224613e-09	-0.264835770355742	3.57712449911902e-08	5
YWHAZ|14-3-3_ZETA	4.09607660747356e-08	-0.265532601547137	5.60650485647944e-07	5
BRD4|BRD4	0.000452998739631391	-0.272773161037172	0.00116713792916794	5
TFRC|TFRC	1.94045610594995e-06	-0.279613220572129	1.14854023568389e-05	5
MAPK1|ERK2	1.56437540723862e-10	-0.291196503136191	6.85196428370516e-09	5
GAPDH|GAPDH	0.000921013826298175	-0.298673297798956	0.0021924133473837	5
SQSTM1|P62-LCK-LIGAND	0.00618220949778542	-0.324026517681272	0.0117730772175218	5
SYK|SYK	1.34737263859718e-05	-0.335195132063429	5.36499287005059e-05	5
FN1|FIBRONECTIN	1.34625170276796e-05	-0.385248286214964	5.36499287005059e-05	5
SERPINE1|PAI-1	1.80167908395762e-06	-0.483444870534799	1.09602144274089e-05	5