Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.041 0.113 0.354 59.0 -9999.0 0.0 59.0 KIRREL -0.01 0.092 -9999.0 0.0 -0.503 17.0 17.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.041 0.113 -9999.0 0.0 -0.355 59.0 59.0 PLCG1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.028 0.079 -9999.0 0.0 -0.26 4.0 4.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.005 0.058 -9999.0 0.0 -9999.0 0.0 0.0 FYN -0.012 0.076 -9999.0 0.0 -0.245 17.0 17.0 mol:Ca2+ -0.028 0.078 -9999.0 0.0 -9999.0 0.0 0.0 mol:DAG -0.028 0.079 -9999.0 0.0 -9999.0 0.0 0.0 NPHS2 -0.002 0.015 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.028 0.079 -9999.0 0.0 -9999.0 0.0 0.0 regulation of endocytosis -0.023 0.065 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/Cholesterol -0.029 0.081 -9999.0 0.0 -0.254 59.0 59.0 establishment of cell polarity -0.041 0.113 -9999.0 0.0 -0.354 59.0 59.0 Nephrin/NEPH1/podocin/NCK1-2 -0.025 0.07 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/beta Arrestin2 -0.011 0.071 -9999.0 0.0 -9999.0 0.0 0.0 NPHS1 -0.035 0.139 -9999.0 0.0 -0.501 42.0 42.0 Nephrin/NEPH1/podocin -0.026 0.071 -9999.0 0.0 -0.246 17.0 17.0 TJP1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.028 0.079 -9999.0 0.0 -9999.0 0.0 0.0 CD2AP 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.028 0.079 -9999.0 0.0 -9999.0 0.0 0.0 GRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.031 0.108 -9999.0 0.0 -0.298 39.0 39.0 cytoskeleton organization 0.007 0.067 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1 -0.028 0.078 -9999.0 0.0 -0.246 59.0 59.0 Nephrin/NEPH1/ZO-1 -0.031 0.087 -9999.0 0.0 -0.273 59.0 59.0