Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.093	0.184	0.309	6.0	-0.503	46.0	52.0
IHH	-0.016	0.128	0.274	7.0	-0.375	47.0	54.0
SHH Np/Cholesterol/GAS1	-0.036	0.059	0.114	1.0	-0.184	65.0	66.0
LRPAP1	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.036	0.058	0.183	65.0	-0.113	1.0	66.0
SMO/beta Arrestin2	-0.148	0.184	0.3	2.0	-0.328	203.0	205.0
SMO	-0.152	0.188	0.342	1.0	-0.338	214.0	215.0
AKT1	-0.082	0.142	0.265	1.0	-0.48	35.0	36.0
ARRB2	0.02	0.006	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.02	0.016	-9999.0	0.0	-0.326	1.0	1.0
ADRBK1	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.15	0.185	0.341	1.0	-0.334	214.0	215.0
STIL	-0.089	0.143	0.264	11.0	-0.322	68.0	79.0
DHH N/PTCH2	0.012	0.067	-9999.0	0.0	-0.229	36.0	36.0
DHH N/PTCH1	-0.11	0.154	-9999.0	0.0	-0.365	63.0	63.0
PIK3CA	0.02	0.004	-9999.0	0.0	-9999.0	0.0	0.0
DHH	-0.004	0.089	-9999.0	0.0	-0.326	36.0	36.0
PTHLH	-0.127	0.224	0.381	5.0	-0.572	42.0	47.0
determination of left/right symmetry	-0.15	0.185	0.341	1.0	-0.334	214.0	215.0
PIK3R1	0.02	0.016	-9999.0	0.0	-0.326	1.0	1.0
skeletal system development	-0.126	0.223	0.38	5.0	-0.568	42.0	47.0
IHH N/Hhip	-0.221	0.18	0.208	3.0	-0.319	371.0	374.0
DHH N/Hhip	-0.121	0.142	-9999.0	0.0	-0.245	280.0	280.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.15	0.185	0.341	1.0	-0.334	214.0	215.0
pancreas development	-0.164	0.172	-9999.0	0.0	-0.325	273.0	273.0
HHAT	0.018	0.022	-9999.0	0.0	-0.326	2.0	2.0
PI3K	0.029	0.014	-9999.0	0.0	-0.229	1.0	1.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.012	0.055	-9999.0	0.0	-0.326	13.0	13.0
somite specification	-0.15	0.185	0.341	1.0	-0.334	214.0	215.0
SHH Np/Cholesterol/PTCH1	-0.1	0.14	0.175	1.0	-0.34	71.0	72.0
SHH Np/Cholesterol/PTCH2	-0.034	0.052	0.114	1.0	-0.176	60.0	61.0
SHH Np/Cholesterol/Megalin	-0.07	0.087	0.114	1.0	-0.192	161.0	162.0
SHH	-0.039	0.07	0.155	1.0	-0.23	60.0	61.0
catabolic process	-0.11	0.162	0.232	2.0	-0.406	47.0	49.0
SMO/Vitamin D3	-0.122	0.176	0.37	2.0	-0.408	68.0	70.0
SHH Np/Cholesterol/Hhip	-0.104	0.101	0.114	1.0	-0.199	252.0	253.0
LRP2	-0.073	0.155	0.324	1.0	-0.326	139.0	140.0
receptor-mediated endocytosis	-0.171	0.186	0.303	2.0	-0.414	135.0	137.0
SHH Np/Cholesterol/BOC	-0.033	0.052	0.114	1.0	-0.176	59.0	60.0
SHH Np/Cholesterol/CDO	-0.035	0.056	0.114	1.0	-0.179	64.0	65.0
mesenchymal cell differentiation	0.104	0.101	0.198	252.0	-0.113	1.0	253.0
mol:Vitamin D3	-0.093	0.153	0.387	5.0	-0.345	69.0	74.0
IHH N/PTCH2	-0.097	0.128	0.208	4.0	-0.21	279.0	283.0
CDON	0.013	0.048	-9999.0	0.0	-0.326	10.0	10.0
IHH N/PTCH1	-0.102	0.175	0.27	2.0	-0.388	53.0	55.0
Megalin/LRPAP1	-0.038	0.115	0.234	1.0	-0.229	136.0	137.0
PTCH2	0.02	0.016	-9999.0	0.0	-0.326	1.0	1.0
SHH Np/Cholesterol	-0.029	0.052	-9999.0	0.0	-0.17	60.0	60.0
PTCH1	-0.111	0.163	0.232	2.0	-0.407	47.0	49.0
HHIP	-0.164	0.173	-9999.0	0.0	-0.326	273.0	273.0