Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.029 0.174 -9999.0 0.0 -0.882 1.0 1.0 MAP3K8 0.016 0.115 -9999.0 0.0 -0.621 1.0 1.0 FOS 0.027 0.109 -9999.0 0.0 -0.523 1.0 1.0 PRKCA 0.007 0.123 -9999.0 0.0 -0.422 2.0 2.0 PTPN7 0.033 0.015 -9999.0 0.0 -9999.0 0.0 0.0 HRAS 0.035 0.009 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.0 0.004 -9999.0 0.0 -0.009 5.0 5.0 NRAS 0.021 0.059 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.043 0.054 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.038 0.056 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K1 0.006 0.12 -9999.0 0.0 -0.59 1.0 1.0 ELK1 0.034 0.014 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.002 0.098 -9999.0 0.0 -0.529 1.0 1.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.003 5.0 5.0 MAPK1 0.026 0.082 -9999.0 0.0 -9999.0 0.0 0.0 RAF1 0.001 0.097 -9999.0 0.0 -0.529 1.0 1.0 KRAS 0.018 0.06 -9999.0 0.0 -0.209 2.0 2.0