Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.02 0.154 -9999.0 0.0 -0.527 17.0 17.0 MAP3K8 0.017 0.028 -9999.0 0.0 -0.533 1.0 1.0 FOS -0.014 0.12 -9999.0 0.0 -0.475 16.0 16.0 PRKCA 0.015 0.038 -9999.0 0.0 -0.537 2.0 2.0 PTPN7 0.016 0.035 0.378 1.0 -0.533 1.0 2.0 HRAS 0.022 0.004 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.011 0.121 -9999.0 0.0 -0.534 25.0 25.0 NRAS 0.021 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.03 0.026 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.001 0.094 -9999.0 0.0 -0.596 8.0 8.0 MAP2K1 -0.016 0.117 -9999.0 0.0 -0.437 29.0 29.0 ELK1 0.015 0.02 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.012 0.099 -9999.0 0.0 -0.42 25.0 25.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 60.0 60.0 MAPK1 0.001 0.091 -9999.0 0.0 -0.502 9.0 9.0 RAF1 -0.015 0.111 -9999.0 0.0 -0.466 25.0 25.0 KRAS 0.021 0.006 -9999.0 0.0 -9999.0 0.0 0.0