Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.243 0.284 0.519 42.0 -9999.0 0.0 42.0 KIRREL -0.086 0.218 -9999.0 0.0 -0.685 10.0 10.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.244 0.285 -9999.0 0.0 -0.52 42.0 42.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.193 0.218 -9999.0 0.0 -0.434 32.0 32.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.133 0.202 -9999.0 0.0 -0.368 28.0 28.0 FYN -0.178 0.223 -9999.0 0.0 -0.417 32.0 32.0 mol:Ca2+ -0.191 0.216 -9999.0 0.0 -0.429 32.0 32.0 mol:DAG -0.192 0.217 -9999.0 0.0 -0.432 32.0 32.0 NPHS2 -0.041 0.094 -9999.0 0.0 -0.613 2.0 2.0 mol:IP3 -0.192 0.217 -9999.0 0.0 -0.432 32.0 32.0 regulation of endocytosis -0.16 0.211 -9999.0 0.0 -0.607 8.0 8.0 Nephrin/NEPH1/podocin/Cholesterol -0.197 0.222 -9999.0 0.0 -0.418 38.0 38.0 establishment of cell polarity -0.243 0.284 -9999.0 0.0 -0.519 42.0 42.0 Nephrin/NEPH1/podocin/NCK1-2 -0.178 0.212 -9999.0 0.0 -0.653 8.0 8.0 Nephrin/NEPH1/beta Arrestin2 -0.162 0.215 -9999.0 0.0 -0.618 8.0 8.0 NPHS1 -0.273 0.319 -9999.0 0.0 -0.633 38.0 38.0 Nephrin/NEPH1/podocin -0.181 0.223 -9999.0 0.0 -0.42 32.0 32.0 TJP1 0.007 0.072 -9999.0 0.0 -0.657 1.0 1.0 NCK1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.007 0.072 -9999.0 0.0 -0.657 1.0 1.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.193 0.218 -9999.0 0.0 -0.434 32.0 32.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.193 0.218 -9999.0 0.0 -0.434 32.0 32.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.203 0.235 -9999.0 0.0 -0.434 34.0 34.0 cytoskeleton organization -0.164 0.239 -9999.0 0.0 -0.449 29.0 29.0 Nephrin/NEPH1 -0.177 0.216 -9999.0 0.0 -0.381 42.0 42.0 Nephrin/NEPH1/ZO-1 -0.206 0.24 -9999.0 0.0 -0.462 32.0 32.0