Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.074 0.165 0.358 71.0 -9999.0 0.0 71.0 KIRREL -0.002 0.048 -9999.0 0.0 -0.439 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.074 0.166 -9999.0 0.0 -0.359 71.0 71.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.047 0.13 -9999.0 0.0 -0.368 31.0 31.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.024 0.101 -9999.0 0.0 -0.302 26.0 26.0 FYN -0.05 0.125 -9999.0 0.0 -0.35 34.0 34.0 mol:Ca2+ -0.05 0.127 -9999.0 0.0 -0.365 31.0 31.0 mol:DAG -0.047 0.129 -9999.0 0.0 -0.366 31.0 31.0 NPHS2 -0.016 0.068 -9999.0 0.0 -0.435 7.0 7.0 mol:IP3 -0.047 0.129 -9999.0 0.0 -0.366 31.0 31.0 regulation of endocytosis -0.04 0.118 -9999.0 0.0 -0.324 34.0 34.0 Nephrin/NEPH1/podocin/Cholesterol -0.055 0.129 -9999.0 0.0 -0.371 32.0 32.0 establishment of cell polarity -0.074 0.165 -9999.0 0.0 -0.358 71.0 71.0 Nephrin/NEPH1/podocin/NCK1-2 -0.035 0.119 -9999.0 0.0 -0.331 31.0 31.0 Nephrin/NEPH1/beta Arrestin2 -0.04 0.12 -9999.0 0.0 -0.328 34.0 34.0 NPHS1 -0.108 0.22 -9999.0 0.0 -0.495 70.0 70.0 Nephrin/NEPH1/podocin -0.05 0.126 -9999.0 0.0 -0.352 34.0 34.0 TJP1 0.011 0.024 -9999.0 0.0 -0.408 1.0 1.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.047 0.13 -9999.0 0.0 -0.368 31.0 31.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.047 0.13 -9999.0 0.0 -0.368 31.0 31.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.057 0.136 -9999.0 0.0 -0.359 39.0 39.0 cytoskeleton organization -0.03 0.126 -9999.0 0.0 -0.377 27.0 27.0 Nephrin/NEPH1 -0.05 0.118 -9999.0 0.0 -0.332 32.0 32.0 Nephrin/NEPH1/ZO-1 -0.05 0.134 -9999.0 0.0 -0.389 27.0 27.0