Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.234 0.279 0.526 82.0 -9999.0 0.0 82.0 KIRREL -0.07 0.198 -9999.0 0.0 -0.694 16.0 16.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.235 0.279 -9999.0 0.0 -0.528 82.0 82.0 PLCG1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.051 -9999.0 0.0 -0.67 1.0 1.0 WASL 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.186 0.228 -9999.0 0.0 -0.397 90.0 90.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.147 0.193 -9999.0 0.0 -0.582 9.0 9.0 FYN -0.181 0.216 -9999.0 0.0 -0.38 90.0 90.0 mol:Ca2+ -0.201 0.21 -9999.0 0.0 -0.692 9.0 9.0 mol:DAG -0.186 0.225 -9999.0 0.0 -0.697 9.0 9.0 NPHS2 -0.067 0.169 -9999.0 0.0 -0.684 12.0 12.0 mol:IP3 -0.186 0.225 -9999.0 0.0 -0.697 9.0 9.0 regulation of endocytosis -0.164 0.209 -9999.0 0.0 -0.653 10.0 10.0 Nephrin/NEPH1/podocin/Cholesterol -0.196 0.227 -9999.0 0.0 -0.406 91.0 91.0 establishment of cell polarity -0.234 0.279 -9999.0 0.0 -0.526 82.0 82.0 Nephrin/NEPH1/podocin/NCK1-2 -0.162 0.212 -9999.0 0.0 -0.65 9.0 9.0 Nephrin/NEPH1/beta Arrestin2 -0.165 0.212 -9999.0 0.0 -0.664 10.0 10.0 NPHS1 -0.267 0.335 -9999.0 0.0 -0.677 71.0 71.0 Nephrin/NEPH1/podocin -0.182 0.218 -9999.0 0.0 -0.383 90.0 90.0 TJP1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.186 0.228 -9999.0 0.0 -0.702 9.0 9.0 CD2AP 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.186 0.228 -9999.0 0.0 -0.397 89.0 89.0 GRB2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.179 0.224 -9999.0 0.0 -0.697 12.0 12.0 cytoskeleton organization -0.184 0.241 -9999.0 0.0 -0.426 71.0 71.0 Nephrin/NEPH1 -0.17 0.209 -9999.0 0.0 -0.386 82.0 82.0 Nephrin/NEPH1/ZO-1 -0.181 0.232 -9999.0 0.0 -0.422 82.0 82.0